Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	BCL6B ZNF17 ZNF845 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF853 ZNF467 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	1.81e-06	1412	79	19	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	BCL6B ZNF17 ZNF845 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 PRDM1	2.94e-06	1459	79	19	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	BCL6B ZNF17 ZNF845 ZNF493 ZNF473 ZNF549 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF853 ZNF467 ZNF714 ZKSCAN5 ZNF786 PRDM1	5.77e-06	1244	79	17	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	BCL6B ZNF17 ZNF845 ZNF493 ZNF473 ZNF549 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF853 ZNF467 ZNF714 ZKSCAN5 ZNF786 PRDM1	7.67e-06	1271	79	17	GO:0000987
Domain	-	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	3.21e-14	679	78	22	3.30.160.60
Domain	zf-C2H2	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	4.86e-14	693	78	22	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	5.01e-14	694	78	22	IPR013087
Domain	ZINC_FINGER_C2H2_2	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	4.63e-13	775	78	22	PS50157
Domain	ZINC_FINGER_C2H2_1	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	4.87e-13	777	78	22	PS00028
Domain	Znf_C2H2-like	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	7.89e-13	796	78	22	IPR015880
Domain	Znf_C2H2	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	9.87e-13	805	78	22	IPR007087
Domain	ZnF_C2H2	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	1.06e-12	808	78	22	SM00355
Domain	zf-C2H2_6	ZNF17 ZNF845 ZNF493 ZNF473 ZNF549 ZNF480 ZNF431 ZNF736 ZNF467 ZNF714 ZKSCAN5 PRDM1	6.66e-09	314	78	12	PF13912
Domain	KRAB	ZNF17 ZNF845 ZNF473 ZNF549 ZNF641 ZNF480 ZNF431 ZNF736 ZNF230 ZNF714 ZKSCAN5 ZNF786	2.85e-08	358	78	12	PS50805
Domain	KRAB	ZNF17 ZNF845 ZNF473 ZNF549 ZNF641 ZNF480 ZNF431 ZNF736 ZNF230 ZNF714 ZKSCAN5 ZNF786	3.98e-08	369	78	12	SM00349
Domain	KRAB	ZNF17 ZNF845 ZNF473 ZNF549 ZNF641 ZNF480 ZNF431 ZNF736 ZNF230 ZNF714 ZKSCAN5 ZNF786	4.10e-08	370	78	12	IPR001909
Domain	KRAB	ZNF17 ZNF845 ZNF473 ZNF549 ZNF641 ZNF480 ZNF431 ZNF736 ZNF230 ZKSCAN5 ZNF786	2.72e-07	358	78	11	PF01352
Domain	TROVE_dom	RO60 TEP1	1.72e-05	2	78	2	IPR008858
Domain	TROVE	RO60 TEP1	1.72e-05	2	78	2	PF05731
Domain	TROVE	RO60 TEP1	1.72e-05	2	78	2	PS50988
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	AURKA EFHB MAPKAPK5 PLK3	1.98e-04	69	78	4	IPR020636
Domain	APC_su10/DOC_dom	MYCBP2 ZZEF1	3.57e-04	7	78	2	IPR004939
Domain	DOC	MYCBP2 ZZEF1	3.57e-04	7	78	2	PS51284
Domain	APC10	MYCBP2 ZZEF1	3.57e-04	7	78	2	SM01337
Domain	ANAPC10	MYCBP2 ZZEF1	3.57e-04	7	78	2	PF03256
Domain	LRR_5	LHCGR LINGO1	7.58e-04	10	78	2	PF13306
Domain	LRR_5	LHCGR LINGO1	7.58e-04	10	78	2	IPR026906
Domain	Ser/Thr_kinase_AS	AURKA MINK1 MAPKAPK5 MAP3K6 PLK3 PKN3	3.78e-03	357	78	6	IPR008271
Domain	S_TKc	AURKA MINK1 MAPKAPK5 MAP3K6 PLK3 PKN3	3.89e-03	359	78	6	SM00220
Domain	PROTEIN_KINASE_ST	AURKA MINK1 MAPKAPK5 MAP3K6 PLK3 PKN3	4.05e-03	362	78	6	PS00108
Domain	NACHT	NLRP12 TEP1	4.12e-03	23	78	2	PS50837
Domain	NACHT_NTPase	NLRP12 TEP1	4.12e-03	23	78	2	IPR007111
Domain	Pkinase	AURKA MINK1 MAPKAPK5 MAP3K6 PLK3 PKN3	5.18e-03	381	78	6	PF00069
Domain	Kinase-like_dom	AURKA MINK1 ARHGAP35 MAPKAPK5 MAP3K6 PLK3 PKN3	7.46e-03	542	78	7	IPR011009
Domain	PROTEIN_KINASE_ATP	AURKA MINK1 MAPKAPK5 MAP3K6 PLK3 PKN3	1.24e-02	459	78	6	PS00107
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	AURKA ZNF17 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 NELFB ZNF480 ZNF431 ZNF736 BCL6 ZNF230 MAPKAPK5 ZNF714 ZKSCAN5 PLK3 ZNF786 PRDM1	4.12e-07	1387	54	19	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	AURKA ZNF845 ZNF775 ZNF493 ZNF473 ZNF641 NELFB ZNF736 MAPKAPK5 ZKSCAN5 PLK3 ZNF786	2.59e-05	768	54	12	MM14851
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCBP2 FNTB NINL MUS81 ZER1 ZFYVE26 TBC1D25 SFI1 ARHGAP35 TEP1 ZZEF1 MAPKAPK5 SYNE4 IQGAP3 PLK3 PKN3	3.87e-09	1105	80	16	35748872
Pubmed	[Increased expressions of Blimp-1 and Bcl-6 in the deciduas of patients with unexplained recurrent spontaneous abortion].	BCL6 PRDM1	5.23e-06	2	80	2	27363279
Pubmed	Decreased Bcl-6 and increased Blimp-1 in the peritoneal cavity of patients with endometriosis.	BCL6 PRDM1	5.23e-06	2	80	2	26054109
Pubmed	BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor.	BCL6B BCL6	5.23e-06	2	80	2	9632807
Pubmed	Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas.	BCL6 PRDM1	5.23e-06	2	80	2	20966935
Pubmed	Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits.	BCL6 PRDM1	5.23e-06	2	80	2	32572238
Pubmed	A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers.	BCL6 PRDM1	5.23e-06	2	80	2	28698369
Pubmed	Dependence on Bcl6 and Blimp1 drive distinct differentiation of murine memory and follicular helper CD4+ T cells.	BCL6 PRDM1	5.23e-06	2	80	2	34792530
Pubmed	Bcl6 and Blimp1 reciprocally regulate ST2+ Treg-cell development in the context of allergic airway inflammation.	BCL6 PRDM1	5.23e-06	2	80	2	32179158
Pubmed	Specification of the germ cell lineage in mice: a process orchestrated by the PR-domain proteins, Blimp1 and Prdm14.	PRDM14 PRDM1	5.23e-06	2	80	2	19001867
Pubmed	Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression.	BCL6 PRDM1	5.23e-06	2	80	2	18684923
Pubmed	Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.	BCL6 PRDM1	1.57e-05	3	80	2	18256039
Pubmed	Physical and functional interactions between mitotic kinases during polyploidization and megakaryocytic differentiation.	AURKA PLK3	1.57e-05	3	80	2	15190214
Pubmed	Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism.	BCL6 PRDM1	1.57e-05	3	80	2	24591370
Pubmed	IFNAR1 signaling in NK cells promotes persistent virus infection.	BCL6 PRDM1	1.57e-05	3	80	2	33771858
Pubmed	Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1.	NLRP12 PRDM1	1.57e-05	3	80	2	19234190
Pubmed	AIM2 deficiency in B cells ameliorates systemic lupus erythematosus by regulating Blimp-1-Bcl-6 axis-mediated B-cell differentiation.	BCL6 PRDM1	1.57e-05	3	80	2	34521812
Pubmed	Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification.	BCL6 PRDM1	1.57e-05	3	80	2	24009228
Pubmed	Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice.	BCL6B BCL6	1.57e-05	3	80	2	17526724
Pubmed	Inflammasome-independent role of NLRP12 in suppressing colonic inflammation regulated by Blimp-1.	NLRP12 PRDM1	1.57e-05	3	80	2	27105524
Pubmed	A rapid computational approach identifies SPICE1 as an Aurora kinase substrate.	AURKA SPICE1	1.57e-05	3	80	2	30485161
Pubmed	STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation.	BCL6 PRDM1	1.57e-05	3	80	2	18354204
Pubmed	Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition.	BCL6 PRDM1	1.57e-05	3	80	2	22406270
Pubmed	A tripartite transcription factor network regulates primordial germ cell specification in mice.	PRDM14 PRDM1	1.57e-05	3	80	2	23851488
Pubmed	BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27.	BCL6B BCL6	1.57e-05	3	80	2	32517789
Pubmed	The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.	BCL6 PRDM1	1.57e-05	3	80	2	20368579
Pubmed	Bcl6-dependent transcriptional repression by BAZF.	BCL6B BCL6	3.13e-05	4	80	2	12659862
Pubmed	Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile.	BCL6 PRDM1	3.13e-05	4	80	2	22406686
Pubmed	Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.	MYCBP2 PAM	3.13e-05	4	80	2	14559897
Pubmed	The transcription factor TCF-1 initiates the differentiation of T(FH) cells during acute viral infection.	BCL6 PRDM1	3.13e-05	4	80	2	26214740
Pubmed	T Helper Plasticity Is Orchestrated by STAT3, Bcl6, and Blimp-1 Balancing Pathology and Protection in Malaria.	BCL6 PRDM1	3.13e-05	4	80	2	32634740
Pubmed	Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteins.	BCL6 PRDM1	3.13e-05	4	80	2	11342629
Pubmed	ZER1 Contributes to the Carcinogenic Activity of High-Risk HPV E7 Proteins.	CUL2 ZER1	3.13e-05	4	80	2	36346242
Pubmed	Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice.	BCL6 PRDM1	3.13e-05	4	80	2	28586108
Pubmed	A role for Blimp1 in the transcriptional network controlling natural killer cell maturation.	BCL6 PRDM1	3.13e-05	4	80	2	21131593
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	BCL6B ZNF473 ZNF641 NELFB BCL6 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF292	3.30e-05	877	80	10	20211142
Pubmed	A T follicular helper cell origin for T regulatory type 1 cells.	BCL6 PRDM1	5.20e-05	5	80	2	36973489
Pubmed	Smad4 is required to inhibit osteoclastogenesis and maintain bone mass.	BCL6 PRDM1	5.20e-05	5	80	2	27731422
Pubmed	Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.	BCL6 PRDM1	5.20e-05	5	80	2	19608860
Pubmed	Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation.	BCL6 PRDM1	5.20e-05	5	80	2	14647274
Pubmed	Regulated selection of germinal-center cells into the memory B cell compartment.	BCL6 PRDM1	5.20e-05	5	80	2	27158841
Pubmed	The Caenorhabditis elegans cell-cycle regulator ZYG-11 defines a conserved family of CUL-2 complex components.	CUL2 ZER1	5.20e-05	5	80	2	17304241
Pubmed	PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.	MYCBP2 PAM	5.20e-05	5	80	2	29997255
Pubmed	Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene.	BCL6 PRDM1	5.20e-05	5	80	2	12165517
Pubmed	Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation.	PRDM14 PRDM1	5.20e-05	5	80	2	23670199
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF17 ZNF845 ZNF493 ZNF480 ZNF736	6.33e-05	181	80	5	37372979
Pubmed	Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.	BCL6 PRDM1	7.79e-05	6	80	2	28892471
Pubmed	The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.	BCL6 PRDM1	7.79e-05	6	80	2	25288399
Pubmed	A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.	BCL6 PRDM1	7.79e-05	6	80	2	31422869
Pubmed	Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor.	BCL6 PRDM1	7.79e-05	6	80	2	31722202
Pubmed	A peptide aptamer to antagonize BCL-6 function.	BCL6B BCL6	7.79e-05	6	80	2	16331266
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MLF2 VPS13D MYCBP2 RO60 MCCC2 MAP3K6 IQGAP3 PKN3	7.82e-05	606	80	8	36538041
Pubmed	Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation.	BCL6 PRDM1	1.09e-04	7	80	2	25484301
Pubmed	CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.	BCL6 PRDM1	1.09e-04	7	80	2	27487330
Pubmed	Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung.	BCL6 PRDM1	1.09e-04	7	80	2	32399548
Pubmed	Critical function of Prdm14 for the establishment of the germ cell lineage in mice.	PRDM14 PRDM1	1.45e-04	8	80	2	18622394
Pubmed	Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.	TNS2 PLK3	1.45e-04	8	80	2	12548019
Pubmed	Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus.	BCL6 PRDM1	1.45e-04	8	80	2	27806296
Pubmed	The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.	AURKA TNS2 BCL6 IQGAP3 PRDM1	1.83e-04	227	80	5	26410627
Pubmed	IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells.	BCL6 PRDM1	2.32e-04	10	80	2	32130409
Pubmed	HIV-1 Tat affects the programming and functionality of human CD8⁺ T cells by modulating the expression of T-box transcription factors.	BCL6 PRDM1	2.32e-04	10	80	2	24841128
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	MLF2 LETMD1 MCCC2 PLD2 ZNF467 PRDM14	3.10e-04	396	80	6	26687479
Pubmed	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	GNL2 ZER1 PKN3	3.30e-04	58	80	3	24144296
Pubmed	USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.	MYCBP2 PAM	3.40e-04	12	80	2	29293652
Pubmed	Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint.	AURKA PLK3	3.40e-04	12	80	2	22617334
Pubmed	PRMT7 is involved in regulation of germ cell proliferation during embryonic stage.	PRDM14 PRDM1	4.01e-04	13	80	2	33008598
Pubmed	Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.	PRDM14 PRDM1	5.38e-04	15	80	2	29320730
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TBC1D8 CUL2 MLF2 DCAF13 MYCBP2 MINK1 GNL2 SDF2L1 SMARCAD1 MCCC2 SPICE1	5.87e-04	1487	80	11	33957083
Pubmed	Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas.	BCL6 PRDM1	6.14e-04	16	80	2	24487434
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	LETMD1 CDH22 NINL ZFYVE26 TEP1 MAP3K6 ZNF714 PLK3	6.59e-04	832	80	8	36724073
Pubmed	SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.	MLF2 LINGO1	6.95e-04	17	80	2	31171447
Pubmed	Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.	ZNF473 NELFB SMARCAD1	7.30e-04	76	80	3	10574461
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL2 MINK1 PAM SMARCAD1 ZZEF1 MAP3K6 IQGAP3	7.53e-04	650	80	7	38777146
Pubmed	Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.	CUL2 ZER1	7.81e-04	18	80	2	18187417
Pubmed	IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.	BCL6 PRDM1	7.81e-04	18	80	2	26426795
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	BCL6B BCL6	8.71e-04	19	80	2	30385546
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	BCL6B BCL6	1.17e-03	22	80	2	1946370
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	BCL6B BCL6	1.17e-03	22	80	2	1505991
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	AURKA MYCBP2 SPICE1	1.66e-03	101	80	3	24613305
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	AURKA OCA2 BCL6 ZNF230 TEP1	1.74e-03	374	80	5	19625176
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CUL2 MLF2 FNTB RPS9 NELFB RPUSD2 SDF2L1 RO60 SMARCAD1 ZZEF1	1.83e-03	1455	80	10	22863883
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	AURKA OCA2 BCL6 ZNF230 TEP1	1.89e-03	381	80	5	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	AURKA OCA2 BCL6 ZNF230 TEP1	1.91e-03	382	80	5	19170196
Pubmed	CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.	CUL2 MLF2 SDF2L1	2.01e-03	108	80	3	30166453
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF493 ZNF736	2.04e-03	29	80	2	14563677
Interaction	FTL interactions	AURKA LETMD1 DCAF13 MUS81 SFI1 PLD2 ARHGAP35 TEP1 IQGAP3	7.07e-06	348	77	9	int:FTL
Interaction	LTBP2 interactions	ZNF17 ZNF775 ZNF480 ZNF431 ZNF714	1.84e-05	85	77	5	int:LTBP2
Interaction	TOP3B interactions	CUL2 MYCBP2 FNTB NINL MUS81 ZER1 ZFYVE26 TBC1D25 SFI1 ARHGAP35 TEP1 ZZEF1 MAPKAPK5 SYNE4 IQGAP3 PLK3 PKN3	3.14e-05	1470	77	17	int:TOP3B
Interaction	MDFI interactions	BCL6B CCDC185 ZNF575 MUS81 ZFYVE26 SFI1 BCL6 ZNF230 ZNF786	3.77e-05	430	77	9	int:MDFI
Interaction	PIPSL interactions	LETMD1 DCAF13 MINK1 SFI1 PLD2 TEP1 IQGAP3	5.02e-05	252	77	7	int:PIPSL
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	VN1R4 ZNF17 NLRP12 ZNF845 ZNF473 ZNF549 RPS9 ZNF575 ZNF480 ARHGAP35 ZNF230 RINL SYNE4	1.44e-07	1192	80	13	chr19q13
Cytoband	7q36.1	ZNF775 ZNF467 ZNF786	3.02e-04	74	80	3	7q36.1
Cytoband	19p12	ZNF493 ZNF431 ZNF714	5.37e-04	90	80	3	19p12
Cytoband	19q13.31	ZNF575 ZNF230	1.18e-03	29	80	2	19q13.31
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF493 ZNF431 ZNF714	1.30e-03	122	80	3	chr19p12
Cytoband	19q13.42	VN1R4 NLRP12 ZNF845	1.39e-03	125	80	3	19q13.42
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	ZNF775 ZNF467 ZNF786	2.75e-03	159	80	3	chr7q36
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	BCL6B MINK1 PLD2 ZZEF1	3.20e-03	346	80	4	chr17p13
Cytoband	9q34.11	ZER1 PKN3	3.90e-03	53	80	2	9q34.11
Cytoband	17p13.2	MINK1 ZZEF1	4.19e-03	55	80	2	17p13.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	BCL6B ZNF17 ZNF845 ZNF775 ZNF493 ZNF473 ZNF549 ZNF641 ZNF575 ZNF480 ZNF431 ZNF736 BCL6 ZNF230 ZNF853 ZNF467 PRDM14 ZNF714 ZKSCAN5 ZNF786 ZNF292 PRDM1	4.14e-17	718	55	22	28
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM14 PRDM1	1.20e-03	17	55	2	1197
Coexpression	GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN	LHCGR LETMD1 PAM SFI1 RINL ZNF467 PKN3	2.39e-06	199	79	7	M7485
Drug	Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A	VPS13D INPP4A MINK1 ZNF480 ZER1 TEP1 FRMD1	3.89e-06	194	76	7	5268_DN
Drug	Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; PC3; HT_HG-U133A	INPP4A ZNF480 ZER1 RO60 ARHGAP35 ZNF467 TEP1	4.17e-06	196	76	7	4473_DN
Drug	Etodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A	VPS13D MINK1 TNS2 SFI1 ARHGAP35 MAP3K6 PLK3	4.31e-06	197	76	7	2254_DN
Drug	SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A	VPS13D RPS9 ZER1 BCL6 TEP1 MAP3K6 FRMD1	4.31e-06	197	76	7	7060_DN
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	CUL2 ZNF549 ZER1 PLD2 ARHGAP35 ZKSCAN5 PRDM1	4.31e-06	197	76	7	2667_UP
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	ZNF473 INPP4A ZER1 SFI1 PLD2 ZKSCAN5 FRMD1	4.45e-06	198	76	7	3897_DN
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	RO60 OCA2 SFI1 BCL6 ZNF230 PCDH1 FRMD1	4.45e-06	198	76	7	2216_UP
Drug	LY294002; Up 200; 10uM; PC3; HT_HG-U133A	TBC1D8 INPP4A RO60 SFI1 BCL6 PLK3	4.08e-05	189	76	6	5942_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; PC3; HT_HG-U133A	VPS13D MINK1 ZER1 ARHGAP35 TEP1 PLK3	4.20e-05	190	76	6	4582_DN
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A	SFI1 BCL6 ARHGAP35 TEP1 PCDH1 GASK1B	4.20e-05	190	76	6	2887_UP
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	INPP4A MINK1 RPUSD2 TNS2 PLD2 MAP3K6	4.33e-05	191	76	6	2850_DN
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A	SOBP MINK1 ZNF480 ZER1 RO60 PRDM14	4.58e-05	193	76	6	6400_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	VPS13D ZER1 BCL6 ARHGAP35 ZNF230 ZNF292	4.58e-05	193	76	6	3378_DN
Drug	5194442; Up 200; 20uM; PC3; HT_HG-U133A	ZNF473 NINL ZER1 PLD2 BCL6 ZZEF1	4.72e-05	194	76	6	6553_UP
Drug	Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	VPS13D SFI1 BCL6 TEP1 PCDH1 FRMD1	4.72e-05	194	76	6	2863_UP
Drug	Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZNF480 PLD2 ARHGAP35 TEP1	4.86e-05	195	76	6	3295_DN
Drug	Chlorthalidone [77-36-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	MINK1 ZER1 PLD2 ARHGAP35 ZNF230 PLK3	4.86e-05	195	76	6	7152_DN
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A	VPS13D RO60 SFI1 ARHGAP35 FRMD1 PLK3	4.86e-05	195	76	6	4980_DN
Drug	Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A	ZNF493 MINK1 TNS2 ZER1 SFI1 ARHGAP35	5.00e-05	196	76	6	4974_UP
Drug	0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A	CUL2 INPP4A TNS2 ZER1 SFI1 TEP1	5.00e-05	196	76	6	3633_DN
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	VPS13D ZNF473 RPS9 TNS2 ZFYVE26 RO60	5.00e-05	196	76	6	3416_DN
Drug	Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A	INPP4A TNS2 SFI1 TEP1 ZZEF1 FRMD1	5.00e-05	196	76	6	3360_UP
Drug	Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZER1 ARHGAP35 ZNF467 ZNF292	5.00e-05	196	76	6	2856_DN
Drug	Benzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	INPP4A MINK1 RO60 PLD2 ARHGAP35 PLK3	5.00e-05	196	76	6	6669_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; HL60; HG-U133A	ZNF473 INPP4A RPS9 PAM PLD2 BCL6	5.00e-05	196	76	6	2015_UP
Drug	Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; HL60; HT_HG-U133A	CUL2 VPS13D DCAF13 ZNF473 SFI1 PLK3	5.00e-05	196	76	6	2737_DN
Drug	Dimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A	CUL2 VPS13D ZNF473 TNS2 SFI1 ZKSCAN5	5.00e-05	196	76	6	3029_DN
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; HL60; HG-U133A	VPS13D MINK1 RPUSD2 SDF2L1 SFI1 ZKSCAN5	5.14e-05	197	76	6	1767_UP
Drug	Bisoprolol fumarate; Up 200; 9uM; HL60; HT_HG-U133A	ZNF473 INPP4A MINK1 PLD2 ARHGAP35 FRMD1	5.14e-05	197	76	6	1287_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	VPS13D RO60 SFI1 PLD2 ARHGAP35 GASK1B	5.14e-05	197	76	6	1003_UP
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A	VPS13D RPUSD2 TNS2 ZNF480 SFI1 ARHGAP35	5.14e-05	197	76	6	2212_DN
Drug	Chlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TNS2 ZER1 OCA2 SFI1 PCDH1 PRDM14	5.14e-05	197	76	6	4142_DN
Drug	NU1025; Up 200; 100uM; MCF7; HG-U133A	VPS13D INPP4A OCA2 SFI1 PRDM14 FRMD1	5.14e-05	197	76	6	313_UP
Drug	Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZER1 SFI1 BCL6 PLK3	5.14e-05	197	76	6	2328_UP
Drug	fludrocortisone acetate; Up 200; 1uM; MCF7; HG-U133A	VPS13D MYCBP2 RPUSD2 BCL6 PRDM14 FRMD1	5.14e-05	197	76	6	281_UP
Drug	Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A	VPS13D INPP4A MINK1 TNS2 ZER1 BCL6	5.29e-05	198	76	6	6806_UP
Drug	Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A	INPP4A PAM RO60 ARHGAP35 PRDM14 FRMD1	5.29e-05	198	76	6	4301_UP
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ZNF493 INPP4A SFI1 PCDH1 PRDM14 PRDM1	5.29e-05	198	76	6	5670_UP
Drug	Pyrithyldione [77-04-3]; Down 200; 24uM; MCF7; HT_HG-U133A	VPS13D INPP4A RPS9 ZER1 ZZEF1 GASK1B	5.29e-05	198	76	6	6801_DN
Drug	prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	VPS13D INPP4A MINK1 TNS2 RO60 TEP1	5.29e-05	198	76	6	6552_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DCAF13 MINK1 ZNF480 BCL6 ARHGAP35 TEP1	5.29e-05	198	76	6	4348_DN
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A	MINK1 ZER1 SFI1 ZKSCAN5 PLK3 ZNF292	5.29e-05	198	76	6	3581_DN
Drug	Fursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; PC3; HT_HG-U133A	ZNF549 MINK1 RPS9 ZER1 PLD2 BCL6	5.29e-05	198	76	6	6630_DN
Drug	Adrenosterone [382-45-6]; Up 200; 13.4uM; HL60; HT_HG-U133A	INPP4A ZNF549 ZER1 SFI1 PLD2 ZZEF1	5.29e-05	198	76	6	3107_UP
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A	INPP4A MINK1 RPS9 TNS2 ZNF480 SFI1	5.29e-05	198	76	6	1534_DN
Drug	Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; PC3; HT_HG-U133A	INPP4A ZNF549 MINK1 TEP1 PRDM14 ZKSCAN5	5.44e-05	199	76	6	6640_DN
Drug	Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A	DCAF13 RPS9 RPUSD2 TNS2 PLD2 ARHGAP35	5.44e-05	199	76	6	7337_DN
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A	VPS13D RPS9 RPUSD2 TNS2 ZER1 PLK3	5.44e-05	199	76	6	5601_DN
Drug	Elvis	OCA2 PLK3	3.04e-04	8	76	2	CID003083357
Drug	Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ZER1 OCA2 SFI1 ARHGAP35 ZNF230	3.43e-04	180	76	5	4776_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	INPP4A ZER1 RO60 SFI1 BCL6	3.98e-04	186	76	5	6987_UP
Drug	Pregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A	SFI1 BCL6 ARHGAP35 ZZEF1 ZKSCAN5	4.08e-04	187	76	5	2856_UP
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	MINK1 TNS2 ZNF480 MAP3K6 ZKSCAN5	4.29e-04	189	76	5	5208_DN
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A	MINK1 ZER1 OCA2 ARHGAP35 ZZEF1	4.39e-04	190	76	5	2629_UP
Drug	17-AAG; Down 200; 1uM; HL60; HT_HG-U133A	RPUSD2 RO60 SFI1 TEP1 FRMD1	4.39e-04	190	76	5	6177_DN
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A	INPP4A RPS9 RO60 PLD2 ARHGAP35	4.39e-04	190	76	5	5614_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	INPP4A ZNF480 ARHGAP35 TEP1 ZKSCAN5	4.50e-04	191	76	5	3605_DN
Drug	DNA-PK Inhibitor III; Up 200; 1uM; PC3; HT_HG-U133A	VPS13D INPP4A MINK1 ZER1 BCL6	4.61e-04	192	76	5	7548_UP
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	VPS13D INPP4A RPS9 ZER1 ARHGAP35	4.61e-04	192	76	5	1517_DN
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	CUL2 INPP4A MINK1 ARHGAP35 ZNF467	4.61e-04	192	76	5	3382_DN
Drug	Flurandrenolide [1524-88-5]; Down 200; 9.2uM; PC3; HT_HG-U133A	CUL2 ZNF473 MINK1 RPUSD2 ZNF230	4.61e-04	192	76	5	7378_DN
Drug	Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	MINK1 ZER1 RO60 MAP3K6 FRMD1	4.61e-04	192	76	5	7485_UP
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	MINK1 TNS2 ZER1 RO60 SFI1	4.61e-04	192	76	5	2271_DN
Drug	Acetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A	INPP4A MINK1 PLD2 PCDH1 PLK3	4.61e-04	192	76	5	1829_UP
Drug	Nitrofural [59-87-0]; Down 200; 20.2uM; HL60; HT_HG-U133A	VPS13D INPP4A MINK1 TNS2 RO60	4.72e-04	193	76	5	2459_DN
Drug	LY294002; Up 200; 10uM; SKMEL5; HG-U133A	MYCBP2 MINK1 PAM ZNF467 ZKSCAN5	4.72e-04	193	76	5	501_UP
Drug	Myosmine [532-12-7]; Down 200; 27.4uM; MCF7; HT_HG-U133A	INPP4A SFI1 PLD2 ZKSCAN5 FRMD1	4.72e-04	193	76	5	3634_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	TBC1D8 TNS2 SFI1 BCL6 ZKSCAN5	4.83e-04	194	76	5	7001_UP
Drug	Etanidazole [22668-01-5]; Down 200; 18.6uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZER1 ARHGAP35 PCDH1	4.83e-04	194	76	5	6072_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A	ZER1 BCL6 ZNF467 MAP3K6 PLK3	4.83e-04	194	76	5	4559_DN
Drug	Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HT_HG-U133A	INPP4A SFI1 BCL6 ARHGAP35 ZNF467	4.83e-04	194	76	5	4642_UP
Drug	Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ZNF480 OCA2 SFI1 ZZEF1 PLK3	4.83e-04	194	76	5	6507_UP
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A	TBC1D8 ZNF473 MINK1 ZNF480 MAP3K6	4.83e-04	194	76	5	6008_DN
Drug	Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A	VPS13D INPP4A ZER1 PCDH1 FRMD1	4.83e-04	194	76	5	3284_UP
Drug	Benzethonium chloride [121-54-0]; Down 200; 9uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZNF480 ZER1 PLK3	4.83e-04	194	76	5	6070_DN
Drug	0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A	VPS13D INPP4A ZER1 SFI1 ZNF230	4.83e-04	194	76	5	3855_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; PC3; HT_HG-U133A	VPS13D ZNF480 TEP1 PLK3 ZNF292	4.94e-04	195	76	5	6301_UP
Drug	STOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A	INPP4A MINK1 RPS9 GNL2 ZER1	4.94e-04	195	76	5	6561_UP
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	CUL2 VPS13D INPP4A ZER1 TEP1	4.94e-04	195	76	5	4748_DN
Drug	Drofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A	VPS13D MINK1 ZER1 ARHGAP35 ZZEF1	4.94e-04	195	76	5	3455_UP
Drug	Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A	VPS13D INPP4A ARHGAP35 TEP1 PLK3	4.94e-04	195	76	5	4533_DN
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	VPS13D ZNF480 ZER1 SFI1 PLK3	4.94e-04	195	76	5	4737_DN
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; PC3; HT_HG-U133A	INPP4A ZER1 RO60 ARHGAP35 ZKSCAN5	4.94e-04	195	76	5	4211_UP
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	VPS13D ZNF473 TNS2 SFI1 PLD2	4.94e-04	195	76	5	3173_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A	VPS13D DCAF13 ZER1 SFI1 ARHGAP35	4.94e-04	195	76	5	3862_UP
Drug	Etofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A	VPS13D ZNF473 RPUSD2 ZER1 ZZEF1	4.94e-04	195	76	5	7327_DN
Drug	cox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A	INPP4A RPUSD2 BCL6 ZZEF1 PRDM14	4.94e-04	195	76	5	207_UP
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A	ZNF480 ZER1 RO60 PLD2 ZNF467	5.06e-04	196	76	5	1543_DN
Drug	(+,-)-Synephrine [94-07-5]; Down 200; 24uM; MCF7; HT_HG-U133A	DCAF13 INPP4A ZNF480 SFI1 TEP1	5.06e-04	196	76	5	6798_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A	RPS9 GNL2 RO60 TEP1 FRMD1	5.06e-04	196	76	5	6559_UP
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	VPS13D ZNF473 SFI1 TEP1 ZNF292	5.06e-04	196	76	5	3892_DN
Drug	Pheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TNS2 SFI1 ZNF230 TEP1 PCDH1	5.06e-04	196	76	5	4130_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	VPS13D DCAF13 MINK1 TNS2 TEP1	5.06e-04	196	76	5	4697_DN
Drug	Colistin sulfate [1264-72-8]; Down 200; 3uM; MCF7; HT_HG-U133A	CUL2 RPS9 TNS2 ZKSCAN5 GASK1B	5.06e-04	196	76	5	2851_DN
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	ZNF493 OCA2 SFI1 TEP1 FRMD1	5.06e-04	196	76	5	2847_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	INPP4A ZER1 SFI1 PLD2 TEP1	5.06e-04	196	76	5	3872_DN
Drug	Suramin sodium salt; Down 200; 10uM; MCF7; HT_HG-U133A	VPS13D INPP4A BCL6 ARHGAP35 FRMD1	5.06e-04	196	76	5	7496_DN
Drug	Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A	MINK1 ZER1 ARHGAP35 ZNF230 TEP1	5.06e-04	196	76	5	4958_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A	INPP4A TNS2 ZNF480 ARHGAP35 ZNF230	5.06e-04	196	76	5	5751_DN
Drug	Propylthiouracil [51-52-5]; Up 200; 23.4uM; MCF7; HT_HG-U133A	INPP4A ZER1 SFI1 TEP1 FRMD1	5.06e-04	196	76	5	2837_UP
Disease	diabetes mellitus, family history	MYCBP2 PAM	6.37e-06	2	75	2	EFO_0000400, EFO_0000493
Disease	Insulinogenic index measurement	MYCBP2 PAM	6.34e-05	5	75	2	EFO_0009961
Disease	immature granulocyte measurement	NLRP12 PKN3	1.33e-04	7	75	2	EFO_0803543
Disease	diffuse large B-cell lymphoma (is_marker_for)	BCL6 PRDM1	1.77e-04	8	75	2	DOID:0050745 (is_marker_for)
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	MYCBP2 PAM	3.45e-04	11	75	2	EFO_0801871
Disease	ovary epithelial cancer (is_marker_for)	AURKA PLK3	4.88e-04	13	75	2	DOID:2152 (is_marker_for)
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	LINGO1 ZZEF1	5.69e-04	14	75	2	EFO_0006830, EFO_0006896
Disease	early cardiac repolarization measurement	MYCBP2 PAM	5.69e-04	14	75	2	EFO_0004885
Disease	immature granulocyte count	NLRP12 PKN3	8.46e-04	17	75	2	EFO_0803542

Protein segments in the cluster

Peptide	Gene	Start	Entry
HLRELNHLREKNHHI	CCDC185	531	Q8N715
HRAREHHLRLLLYHL	B4GALT3	131	O60512
HQLRREVEIQSHLRH	AURKA	176	O14965
LHRRLESLKRHHASL	CCDC96	521	Q2M329
AILVRDRIHKFHRLV	PAM	451	P19021
HIKRIARHRHLPKSI	DCAF13	386	Q9NV06
ALEHLLARRLHTFHR	OCA2	581	Q04671
KDLLQDRHHRLHLTL	INPP4A	141	Q96PE3
LHDRIRPHNLKVHIL	GNL2	121	Q13823
AIHLDQKLRLRHAIL	LHCGR	471	P22888
LRHCHLLNIAHRDLK	MAPKAPK5	136	Q8IW41
HHALHLTRKVVRNLN	MCCC2	281	Q9HCC0
LLRHRLKTHTTVIHQ	LETMD1	271	Q6P1Q0
HEEIALHRRLRHKNI	MAP3K6	691	O95382
LEKEIERRHHGLHRL	PCDH1	776	Q08174
RKENVHRHALRLLIH	NELFB	496	Q8WX92
LSHLHGLIVLRLRHL	LINGO1	211	Q96FE5
LAKDIRNQHRHRHRR	IQGAP3	1466	Q86VI3
HLERIRRSHQKHNAI	CFAP53	36	Q96M91
ALAHIIQRKHDPRHL	GASK1B	411	Q6UWH4
LHLLRASHQLHLRVR	FRMD1	321	Q8N878
GLHFRHKSQLRLHLR	BCL6B	446	Q8N143
LALRHLHGRVFQLHV	LACTBL1	426	A8MY62
TKIFLENHVRHLHKR	CUL2	61	Q13617
HFRHKSQLRLHLRQK	BCL6	666	P41182
KDRQRALIAAVRHHL	EFHB	541	Q8N7U6
HLVPRLVLQREKHFH	FNTB	66	P49356
VLLILTLRRHHKSHL	CDH22	641	Q9UJ99
HIRDRAHILQRSRNH	MLF2	156	Q15773
HLEALRRQLHVELKV	PKN3	106	Q6P5Z2
HIKHLLHQRQRRIEE	MINK1	386	Q8N4C8
EHQLKELHPLHRLDR	RPUSD2	261	Q8IZ73
KSIHHARVLIRQRHI	RPS9	121	P46781
THHLQCVRKRLLHRQ	SFI1	796	A8K8P3
FEKRDRLRIHILHVH	PRDM14	441	Q9GZV8
RLRIHILHVHEKHRP	PRDM14	446	Q9GZV8
HFDRLVRKHHLGRVL	TBC1D25	646	Q3MII6
LEVLLKHHQHRYLRL	SMARCAD1	886	Q9H4L7
GHQKRLARHQRHSLL	SYNE4	306	Q8N205
RLLHRHIREQLKDLV	PPM1J	171	Q5JR12
DRFLHLHRRTKTHQR	MYCBP2	4286	O75592
FVHLKLHKRLHTRER	PRDM1	671	O75626
GLALRHHSHLQQIRR	NINL	721	Q9Y2I6
HRLVREHLLTNHLKS	RO60	251	P10155
FLQHIHRLKHEHIER	ARHGAP35	321	Q9NRY4
RRHEIHKSKNRALVH	SPICE1	51	Q8N0Z3
VFNRKAKLARHHRIH	ZNF845	951	Q96IR2
LRSRIHERLAHLHAA	RINL	406	Q6ZS11
IELHRDLQHRHIVRF	PLK3	111	Q9H4B4
LLHLSQHKRIHIREN	ZNF431	216	Q8TF32
LLHHVRRLQRHAEER	TEX13D	86	A0A0J9YY54
LLHLHQHKRIHIREN	ZNF714	156	Q96N38
DDHIRVIVQLHKLRH	ZER1	236	Q7Z7L7
FIHKKRLLEHQRIHT	ZNF549	426	Q6P9A3
RHHELILQRLQHAKS	TEP1	541	Q99973
VLKLLNTHHRVRLHS	SDF2L1	41	Q9HCN8
NVIHRALHAHVKAER	SOBP	666	A7XYQ1
HLRYKHRIRVLQGHE	TBC1D8	781	O95759
RLLLLHQRSHHQVEH	ZNF575	226	Q86XF7
HNDKHKAHLIRPRRL	ZNF292	2281	O60281
RHQVGLRIHQRAHAR	ZNF775	201	Q96BV0
FRQKQHLLKHLRTHL	ZNF775	346	Q96BV0
VLLRRHRHQTKKPIH	SLC4A5	211	Q9BY07
LHRHKQRVQHIDRSD	VN1R4	206	Q7Z5H5
SGHLHVRLKQRLLER	nan	111	Q3C1V9
VFNRIAHLARHRKIH	ZNF480	491	Q8WV37
FRLRRLLQVHQHAHG	ZNF786	406	Q8N393
FRHKVQIRRHERQLH	ZNF853	606	P0CG23
SALRIHQRVHLREKL	ZNF230	181	Q9UIE0
LLHLCQHKRIHIREN	ZNF493	66	Q6ZR52
HQRLKAIHLLLRIVR	ZZEF1	2841	O43149
HRRIAHDLRLLLLQH	PRR30	221	Q53SZ7
HFQELHRDLLRHKVL	PLD2	106	O14939
HQKHLLHLLERRDHD	ZFYVE26	1581	Q68DK2
EQRHRGHLRELAHVL	TNS2	151	Q63HR2
KSHLLQHQRIHTRPR	ZNF17	286	P17021
FRKKTHLIRHQRIHT	ZNF467	281	Q7Z7K2
RHSHLIEHLKRHFRE	ZKSCAN5	441	Q9Y2L8
RIFHLTRHQKIHTRK	ZNF473	331	Q8WTR7
HLIRHKRIHTREKLH	ZNF736	411	B4DX44
HRHTHDLRIHQLQVR	VPS13D	2961	Q5THJ4
FGRRHHLIRHQKTHL	ZNF641	301	Q96N77
ALEKLHRLLEHPRHV	NLRP12	346	P59046
LQRLHVTHTVRKLHV	MUS81	291	Q96NY9