Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Cul7	CUL9 CUL7 HERC2	1.83e-07	3	107	3	PF11515
Domain	CPH_domain	CUL9 CUL7 HERC2	1.83e-07	3	107	3	IPR021097
Domain	ARM-type_fold	USP34 DNAJC13 LRRK2 CUL9 HUWE1 CUL7 USP9Y PSME4 NUP188 TAF2 WDFY3	3.93e-06	339	107	11	IPR016024
Domain	APC_su10/DOC_dom	CUL9 CUL7 HERC2	6.29e-06	7	107	3	IPR004939
Domain	DOC	CUL9 CUL7 HERC2	6.29e-06	7	107	3	PS51284
Domain	ANAPC10	CUL9 CUL7 HERC2	6.29e-06	7	107	3	PF03256
Domain	APC10	CUL9 CUL7 HERC2	6.29e-06	7	107	3	SM01337
Domain	Rib_L2_dom2	CUL9 CUL7 HERC2	1.40e-04	18	107	3	IPR014722
Domain	-	CUL9 CUL7 HERC2	1.40e-04	18	107	3	2.30.30.30
Domain	ARM-like	DNAJC13 LRRK2 CUL9 HUWE1 CUL7 USP9Y PSME4 WDFY3	1.63e-04	270	107	8	IPR011989
Domain	LipOase_mml	ALOXE3 ALOX12B	4.80e-04	6	107	2	IPR001885
Domain	LIPOXYGENASE_1	ALOXE3 ALOX12B	4.80e-04	6	107	2	PS00711
Domain	LipOase_C	ALOXE3 ALOX12B	4.80e-04	6	107	2	IPR013819
Domain	LIPOXYGENASE_2	ALOXE3 ALOX12B	4.80e-04	6	107	2	PS00081
Domain	LipOase_Fe_BS	ALOXE3 ALOX12B	4.80e-04	6	107	2	IPR020833
Domain	LipOase_CS	ALOXE3 ALOX12B	4.80e-04	6	107	2	IPR020834
Domain	Lipoxygenase	ALOXE3 ALOX12B	4.80e-04	6	107	2	PF00305
Domain	LIPOXYGENASE_3	ALOXE3 ALOX12B	4.80e-04	6	107	2	PS51393
Domain	LipOase	ALOXE3 ALOX12B	4.80e-04	6	107	2	IPR000907
Domain	HECT	HUWE1 HERC2 HERC6	4.84e-04	27	107	3	PF00632
Domain	HECTc	HUWE1 HERC2 HERC6	4.84e-04	27	107	3	SM00119
Domain	HECT_dom	HUWE1 HERC2 HERC6	4.84e-04	27	107	3	IPR000569
Domain	HECT	HUWE1 HERC2 HERC6	4.84e-04	27	107	3	PS50237
Domain	-	CUL9 CUL7 FURIN HERC2	8.18e-04	73	107	4	2.60.120.260
Domain	Cullin_neddylation_domain	CUL9 CUL7	8.90e-04	8	107	2	IPR019559
Domain	-	MBD1 MBD2	8.90e-04	8	107	2	3.30.890.10
Domain	Cullin_Nedd8	CUL9 CUL7	8.90e-04	8	107	2	PF10557
Domain	Cullin_Nedd8	CUL9 CUL7	8.90e-04	8	107	2	SM00884
Domain	Peptidase_S8_His-AS	TPP2 FURIN	1.14e-03	9	107	2	IPR022398
Domain	Peptidase_S8_Ser-AS	TPP2 FURIN	1.14e-03	9	107	2	IPR023828
Domain	Cullin_homology	CUL9 CUL7	1.14e-03	9	107	2	IPR016158
Domain	Cullin	CUL9 CUL7	1.42e-03	10	107	2	PF00888
Domain	Peptidase_S8_subtilisin-rel	TPP2 FURIN	1.42e-03	10	107	2	IPR015500
Domain	CULLIN_2	CUL9 CUL7	1.42e-03	10	107	2	PS50069
Domain	SUBTILASE_ASP	TPP2 FURIN	1.42e-03	10	107	2	PS00136
Domain	SUBTILASE_HIS	TPP2 FURIN	1.42e-03	10	107	2	PS00137
Domain	SUBTILASE_SER	TPP2 FURIN	1.42e-03	10	107	2	PS00138
Domain	Cullin_N	CUL9 CUL7	1.42e-03	10	107	2	IPR001373
Domain	CULLIN_1	CUL9 CUL7	1.42e-03	10	107	2	PS01256
Domain	-	TPP2 FURIN	1.73e-03	11	107	2	3.40.50.200
Domain	MBD	MBD1 MBD2	1.73e-03	11	107	2	SM00391
Domain	MBD	MBD1 MBD2	1.73e-03	11	107	2	PS50982
Domain	Peptidase_S8/S53_dom	TPP2 FURIN	1.73e-03	11	107	2	IPR000209
Domain	Methyl_CpG_DNA-bd	MBD1 MBD2	1.73e-03	11	107	2	IPR001739
Domain	MBD	MBD1 MBD2	1.73e-03	11	107	2	PF01429
Domain	DNA-bd_dom	MBD1 MBD2	1.73e-03	11	107	2	IPR016177
Domain	Peptidase_S8	TPP2 FURIN	1.73e-03	11	107	2	PF00082
Domain	-	DNAJC13 LRRK2 CUL9 CUL7 PSME4 WDFY3	1.76e-03	222	107	6	1.25.10.10
Domain	Galactose-bd-like	CUL9 CUL7 FURIN HERC2	2.09e-03	94	107	4	IPR008979
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH14	2.83e-03	14	107	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH14	2.83e-03	14	107	2	IPR024743
Domain	MT	DNAH3 DNAH14	2.83e-03	14	107	2	PF12777
Domain	AAA_8	DNAH3 DNAH14	2.83e-03	14	107	2	PF12780
Domain	DHC_fam	DNAH3 DNAH14	3.25e-03	15	107	2	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH14	3.25e-03	15	107	2	PF03028
Domain	Dynein_heavy_dom	DNAH3 DNAH14	3.25e-03	15	107	2	IPR004273
Domain	DUF1605	YTHDC2 DQX1	4.18e-03	17	107	2	IPR011709
Domain	OB_NTP_bind	YTHDC2 DQX1	4.18e-03	17	107	2	PF07717
Domain	LH2	ALOXE3 ALOX12B	4.69e-03	18	107	2	SM00308
Domain	HA2	YTHDC2 DQX1	4.69e-03	18	107	2	SM00847
Domain	HA2	YTHDC2 DQX1	4.69e-03	18	107	2	PF04408
Domain	Helicase-assoc_dom	YTHDC2 DQX1	4.69e-03	18	107	2	IPR007502
Domain	WD40_repeat	LRRK2 WDHD1 WDR11 WDFY3 HERC2 WDR1	4.79e-03	272	107	6	IPR001680
Domain	PUA-like_domain	NSUN6 THYN1	5.22e-03	19	107	2	IPR015947
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 NUP107 MBD1 VPS50 CUL9 QTRT2 YTHDC2 CUL7 CDKAL1 P4HA1 ANAPC1 XYLB NUP188 TAF2 WDFY3 KAT6B MBD2 RSBN1L	1.40e-08	1116	110	18	31753913
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 USP34 AARS1 NUP107 CUL9 YTHDC2 PRPF6 HUWE1 CUL7 ADNP PAICS ANAPC1 NUP188 HERC2	2.07e-08	653	110	14	22586326
Pubmed	Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.	SFRP1 MBD1 MBD2	1.07e-06	7	110	3	24374650
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CFH USP34 AARS1 MBD1 CUL9 HUWE1 USP9Y PAICS CYRIA CELSR3 SLF2 COPS4 ASTN1 WDFY3 HERC2 RSBN1L	2.93e-06	1285	110	16	35914814
Pubmed	Defining the membrane proteome of NK cells.	AARS1 DNAJC13 GPAA1 NUP107 VPS50 AGPAT3 PRPF6 HUWE1 PAICS CDKAL1 WDR11 P4HA1 FURIN NUP188 HERC2	4.25e-06	1168	110	15	19946888
Pubmed	Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.	CUL9 HUWE1 CUL7	4.99e-06	11	110	3	31570706
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	TPP2 USP34 CUL9 CUL7 PSME4 ANAPC1 HERC2	5.30e-06	212	110	7	33853758
Pubmed	Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.	ALOXE3 ALOX12B	9.91e-06	2	110	2	15629692
Pubmed	The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.	ALOXE3 ALOX12B	9.91e-06	2	110	2	24021977
Pubmed	Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.	ALOXE3 ALOX12B	9.91e-06	2	110	2	19131948
Pubmed	Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.	ALOXE3 ALOX12B	9.91e-06	2	110	2	11773004
Pubmed	12R-lipoxygenase deficiency disrupts epidermal barrier function.	ALOXE3 ALOX12B	9.91e-06	2	110	2	17403930
Pubmed	Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.	ALOXE3 ALOX12B	9.91e-06	2	110	2	33435499
Pubmed	Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.	ALOXE3 ALOX12B	9.91e-06	2	110	2	21558561
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	NUP107 YTHDC2 PRPF6 HUWE1 ADNP ANAPC1 HASPIN NUP188 HERC2	1.15e-05	440	110	9	34244565
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 AARS1 VPS50 HUWE1 CDKAL1 CUEDC2 THYN1 WDHD1 P4HA1 ANAPC1 RSBN1L	2.18e-05	733	110	11	34672954
Pubmed	Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation.	ALOXE3 ALOX12B	2.97e-05	3	110	2	22832496
Pubmed	The role of lipoxygenases in epidermis.	ALOXE3 ALOX12B	2.97e-05	3	110	2	23954555
Pubmed	Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression.	MBD1 MBD2	2.97e-05	3	110	2	14610093
Pubmed	Integrative Molecular Analyses of an Individual Transcription Factor-Based Genomic Model for Lung Cancer Prognosis.	SATB2 NPAS2	2.97e-05	3	110	2	34925645
Pubmed	Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.	CUL9 CUL7	2.97e-05	3	110	2	17229476
Pubmed	Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.	CUL9 CUL7	2.97e-05	3	110	2	15964813
Pubmed	Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2.	MBD1 MBD2	2.97e-05	3	110	2	12646234
Pubmed	Silencing of MBD2 and EZH2 inhibits the proliferation of colorectal carcinoma cells by rescuing the expression of SFRP.	SFRP1 MBD2	2.97e-05	3	110	2	34617573
Pubmed	Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13.	ALOXE3 ALOX12B	2.97e-05	3	110	2	17139268
Pubmed	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.	CUL9 CUL7	2.97e-05	3	110	2	17298945
Pubmed	Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients.	ALOXE3 ALOX12B	2.97e-05	3	110	2	19890349
Pubmed	SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation.	MBD1 MBD2	2.97e-05	3	110	2	25798578
Pubmed	Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions.	MBD1 MBD2	2.97e-05	3	110	2	27066839
Pubmed	Common and Distinct Genetic Architecture of Age at Diagnosis of Diabetes in South Indian and European Populations.	CDKAL1 WDR11	2.97e-05	3	110	2	37308106
Pubmed	Genetic association study between methyl-CpG-binding domain genes and schizophrenia among Chinese family trios.	MBD1 MBD2	2.97e-05	3	110	2	24849540
Pubmed	MBD1 Contributes to the Genesis of Acute Pain and Neuropathic Pain by Epigenetic Silencing of Oprm1 and Kcna2 Genes in Primary Sensory Neurons.	MBD1 OPRM1	2.97e-05	3	110	2	30266739
Pubmed	Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity.	MBD1 MBD2	2.97e-05	3	110	2	19781662
Pubmed	cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase.	ALOXE3 ALOX12B	2.97e-05	3	110	2	10366447
Pubmed	A novel p53-binding domain in CUL7.	CUL9 CUL7	2.97e-05	3	110	2	16875676
Pubmed	Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S.	SFRP1 LRRK2	2.97e-05	3	110	2	20130188
Pubmed	Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male.	USP9Y CDY1	2.97e-05	3	110	2	36591797
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	AARS1 VPS50 YTHDC2 PRPF6 USP9Y PAICS P4HA1 COPS4 RSBN1L	3.00e-05	497	110	9	36774506
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	ZNF438 FRMPD2 CUEDC2 WDR11 SLF2 P4HA1 KAT6B VWA2	5.45e-05	415	110	8	16385451
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 SATB2 DNAJC13 NUP107 HUWE1 ADNP SFMBT2 ANAPC1	5.73e-05	418	110	8	34709266
Pubmed	Sex-specific windows for high mRNA expression of DNA methyltransferases 1 and 3A and methyl-CpG-binding domain proteins 2 and 4 in human fetal gonads.	MBD1 MBD2	5.92e-05	4	110	2	16998846
Pubmed	A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression.	ALOXE3 ALOX12B	5.92e-05	4	110	2	11350124
Pubmed	The expression of epidermal lipoxygenases and transglutaminase-1 is perturbed by NIPAL4 mutations: indications of a common metabolic pathway essential for skin barrier homeostasis.	ALOXE3 ALOX12B	5.92e-05	4	110	2	22622417
Pubmed	Proteolytic processing of human zona pellucida proteins.	ZP2 FURIN	5.92e-05	4	110	2	11804956
Pubmed	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	CUL9 CUL7 ANAPC1	5.94e-05	24	110	3	33705438
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HUWE1 HERC2 HERC6	7.59e-05	26	110	3	26949039
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	USP34 TMEM39B ZP2 CDKAL1 MLXIPL CPHXL NLRP5	8.31e-05	326	110	7	17015433
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SATB2 NUP107 MBD1 CUL9 HUWE1 CUL7 ADNP WDHD1 P4HA1 ANAPC1 MBD2	8.87e-05	857	110	11	25609649
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	AARS1 NUP107 PRPF6 HUWE1 WDHD1 P4HA1 ANAPC1	9.31e-05	332	110	7	32786267
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	HUWE1 CUL7 RFX7	9.52e-05	28	110	3	25752541
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	AARS1 DNAJC13 NUP107 PRPF6 HUWE1 ADNP PAICS PSME4 WDR11 TAF2 WDFY3 HERC2 WDR1 ALOX12B	9.58e-05	1353	110	14	29467282
Pubmed	CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.	CUL9 CUL7	9.85e-05	5	110	2	24793696
Pubmed	Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.	MBD1 MBD2	9.85e-05	5	110	2	11371345
Pubmed	PARC and CUL7 form atypical cullin RING ligase complexes.	CUL9 CUL7	9.85e-05	5	110	2	17332328
Pubmed	Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.	ALOXE3 ALOX12B	9.85e-05	5	110	2	17436029
Pubmed	Identification and characterization of a family of mammalian methyl-CpG binding proteins.	MBD1 MBD2	9.85e-05	5	110	2	9774669
Pubmed	Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development.	MBD1 MBD2	9.85e-05	5	110	2	17546630
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 NUP107 VPS50 CUL9 HUWE1 CUL7 BAIAP2L1 SLF2 ANAPC1	1.08e-04	588	110	9	38580884
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NUP107 PRPF6 ADNP WDHD1 NUP188 KAT6B RSBN1L	1.10e-04	341	110	7	32971831
Pubmed	The DNA sequence and comparative analysis of human chromosome 10.	ZNF438 SFMBT2 NSUN6 CUEDC2 WDR11 SLF2 P4HA1	1.18e-04	345	110	7	15164054
Pubmed	The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.	RFX7 COMMD10	1.47e-04	6	110	2	29967452
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DNAJC13 HUWE1 ASTN1 WDFY3	1.72e-04	87	110	4	12465718
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	DNAJC13 CUL9 PRPF6 HUWE1 CUL7 ZNF611 WDR1 RSBN1L	1.86e-04	496	110	8	31343991
Pubmed	HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.	CUL9 HUWE1 CUL7 UBE2E3	1.96e-04	90	110	4	35671810
Pubmed	Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.	MBD1 RFX7	2.06e-04	7	110	2	20062064
Pubmed	Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.	MBD1 MBD2	2.06e-04	7	110	2	17634428
Pubmed	Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.	MBD1 MBD2	2.06e-04	7	110	2	25363021
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DNAJC13 HUWE1 SLF2 HERC2	2.14e-04	92	110	4	15840729
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	CUL9 HUWE1 HERC2 HERC6	2.42e-04	95	110	4	29643511
Pubmed	Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients.	PDE6A OPRM1	2.74e-04	8	110	2	20110084
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	AARS1 DNAJC13 GPAA1 NUP107 FAM210A VPS50 AGPAT3 QTRT2 PRPF6 NPHP4 TMEM120A COPS4 MBD2	2.81e-04	1321	110	13	27173435
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 CUL9 CUL7 ANAPC1 TAF2 MBD2	2.85e-04	282	110	6	23667531
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 SATB2 VPS50 ADNP PSME4 CELSR3 NUP188 KAT6B	2.87e-04	529	110	8	14621295
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	SATB2 SFMBT2 COPS4 HERC2 MBD2	2.99e-04	183	110	5	36129980
Pubmed	Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.	USP34 USP9Y	3.52e-04	9	110	2	37149635
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	TROAP HUWE1 RFX7 ANAPC1	3.67e-04	106	110	4	31024071
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	AARS1 DNAJC13 QTRT2 PRPF6 HUWE1 ADNP PAICS BAIAP2L1 P4HA1 NTM COMMD10 WDR1 UBE2E3	3.90e-04	1367	110	13	32687490
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	USP34 DNAJC13 EFCAB3 NPHP4 MLXIPL TRPM3 HERC2	3.90e-04	420	110	7	28065597
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	NUP107 VPS50 PRPF6 BAIAP2L1 WDR11 ANAPC1 WDR1 MBD2	4.19e-04	560	110	8	35241646
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CFH USP34 B4GALNT1 GPAA1 SLC35A1 PAICS CDKAL1 CELSR3 P4HA1 FURIN COPS4 DNASE2	4.26e-04	1201	110	12	35696571
Pubmed	The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.	LRRK2 HERC2	4.39e-04	10	110	2	26355680
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	USP34 HUWE1	4.39e-04	10	110	2	17478428
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	SATB2 MBD1 HUWE1 RFX7 ADNP WDR11 MBD2	4.55e-04	431	110	7	33660365
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CUL9 HUWE1 CUL7 WDHD1 WDR11 HERC2	4.95e-04	313	110	6	38270169
Pubmed	Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11.	HUWE1 UBE2E3	5.35e-04	11	110	2	11809816
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SATB2 NUP107 MBD1 YTHDC2 PRPF6 HUWE1 ADNP MLXIPL	5.45e-04	583	110	8	29844126
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 TBC1D30 HUWE1 DNAH14 THYN1 TRPM3 P4HA1 DQX1 NUP188	5.63e-04	736	110	9	29676528
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	PRPF6 HUWE1 PSME4 P4HA1 HASPIN	5.72e-04	211	110	5	17314511
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	TPP2 USP34 CUL7 SVEP1 PSME4 COPS4	5.75e-04	322	110	6	26514267
Pubmed	Smad anchor for receptor activation nuclear localization during development identifies Layers V and VI of the neocortex.	SATB2 WDFY3	6.41e-04	12	110	2	32037591
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CUL9 CUL7 ADNP ZP2 CELSR3 APOL5	6.43e-04	329	110	6	17474147
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP34 ARHGAP15 FAM210A SLC35A1 TMEM39B HUWE1 KLHL32 PAICS PSME4 WDHD1 NUP188	6.58e-04	1084	110	11	11544199
Pubmed	The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.	MBD1 MBD2	7.56e-04	13	110	2	12124384
Pubmed	Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes.	MBD1 MBD2	7.56e-04	13	110	2	10441743
Pubmed	Replication of recently described type 2 diabetes gene variants in a South Indian population.	CDKAL1 MLXIPL	7.56e-04	13	110	2	20580033
Pubmed	Autosomal Recessive Congenital Ichthyosis	ALOXE3 ALOX12B	7.56e-04	13	110	2	20301593
Pubmed	Single cell RT-PCR on mouse embryos: a general approach for developmental biology.	MBD1 MBD2	7.56e-04	13	110	2	20300987
Pubmed	BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.	CFH LRRK2 OPRM1	7.95e-04	57	110	3	27433848
Pubmed	Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.	CUL9 CUL7	8.80e-04	14	110	2	22653443
Pubmed	CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.	CUL7 COPS4	8.80e-04	14	110	2	22032989
Interaction	TRIM66 interactions	NUP107 VPS50 CUL9 YTHDC2 CUL7 CDKAL1 P4HA1 NUP188 WDFY3	1.17e-06	205	104	9	int:TRIM66
Interaction	SIRT7 interactions	TPP2 USP34 AARS1 NUP107 CUL9 YTHDC2 PRPF6 HUWE1 CUL7 ADNP PAICS ANAPC1 COPS4 NUP188 HERC2	6.30e-06	744	104	15	int:SIRT7
Cytoband	9q21.12	TMC1 TRPM3	2.48e-04	10	109	2	9q21.12
GeneFamily	Arachidonate lipoxygenases	ALOXE3 ALOX12B	2.07e-04	6	68	2	407
GeneFamily	Cullins	CUL9 CUL7	3.85e-04	8	68	2	1032
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	MBD1 MBD2	7.50e-04	11	68	2	1025
GeneFamily	Dyneins, axonemal	DNAH3 DNAH14	1.83e-03	17	68	2	536
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH BOC SATB2 SFRP1 OVCH1 SVEP1 MLXIPL	2.13e-07	172	108	7	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SATB2 FRMPD2 LRRK2 DNAH14 OPRM1 TRPM3 UBE2E3	2.30e-07	174	108	7	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SATB2 LRRK2 DNAH14 CDKAL1 NTM WDFY3	4.03e-07	189	108	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	TBC1D30 FAM210A USP9Y PAICS P4HA1 ZNF433	2.61e-06	160	108	6	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SATB2 FRMPD2 DNAH14 OPRM1 TRPM3 UBE2E3	4.10e-06	173	108	6	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SATB2 LRRK2 CDKAL1 NTM WDFY3	4.52e-06	176	108	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SATB2 LRRK2 CDKAL1 NTM WDFY3	5.66e-06	183	108	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LRRK2 AGPAT3 CDKAL1 SLF2 GPR137B TAF2	7.01e-06	190	108	6	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	TROAP SFMBT2 DNAH14 MLXIPL XYLB	3.69e-05	154	108	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B4GALNT1 TMC1 NTM FURIN ALOX12B	3.93e-05	156	108	5	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	USP9Y RFX7 MLXIPL WDHD1 MBD2	3.93e-05	156	108	5	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	CV-Mild-4\|CV / Virus stimulation, Condition and Cluster	TBC1D30 FAM210A PAICS P4HA1 ZNF433	4.43e-05	160	108	5	be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH BOC SVEP1 NTM HASPIN	4.70e-05	162	108	5	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH BOC SVEP1 NTM HASPIN	4.70e-05	162	108	5	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TRABD2A ARHGAP15 CENPK DNAH14 HERC6	5.59e-05	168	108	5	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRABD2A SLC22A25 FRMPD2 DNAH14 OPRM1	6.08e-05	171	108	5	9e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BOC METTL4 ADNP NTM GPR137B	6.78e-05	175	108	5	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BOC METTL4 ADNP NTM GPR137B	6.78e-05	175	108	5	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD2 LRRK2 DNAH14 OPRM1 TRPM3	6.96e-05	176	108	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SATB2 ARHGAP15 FRMPD2 DNAH14 UBE2E3	7.54e-05	179	108	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SATB2 LRRK2 NTM WDFY3	8.16e-05	182	108	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRABD2A SATB2 SLC22A25 FRMPD2 NPAS2	8.16e-05	182	108	5	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SATB2 LRRK2 NTM WDFY3	8.37e-05	183	108	5	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	SATB2 LRRK2 MLXIPL TRPM3 XYLB	8.59e-05	184	108	5	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 TMC1 MLXIPL TRPM3 NPAS2	9.04e-05	186	108	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 LRRK2 DNAH14 CDKAL1 NTM	9.50e-05	188	108	5	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH BOC SFMBT2 NTM NUP188	9.99e-05	190	108	5	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARHGAP15 LRRK2 SFMBT2 CYRIA GPR137B	1.02e-04	191	108	5	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH BOC SVEP1 NTM ASTN1	1.05e-04	192	108	5	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TROAP OVCH1 CENPK WDHD1 GPR137B	1.18e-04	197	108	5	d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_T_naive\|Leuk-UTI / Disease, condition lineage and cell class	TRABD2A ARHGAP15 TROAP THYN1 NPAS2	1.24e-04	199	108	5	476daaa0b764f82a0dfb85cc94e5b07a091703bd
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH BOC SFRP1 SVEP1 NTM	1.24e-04	199	108	5	6e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	SATB2 TMEM120A NTM	1.25e-04	40	108	3	a55d9861170f41049748cd093d3d680855553d1d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Neuronal-Neurons\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	SATB2 TMEM120A NTM	1.25e-04	40	108	3	7d7dc8dd5b095b7e3a83cbf840c4ee4f650bbc7c
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH BOC SFRP1 SVEP1 NTM	1.27e-04	200	108	5	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH BOC SFRP1 SVEP1 NTM	1.27e-04	200	108	5	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	medial-mesenchymal-Adventitial_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH BOC SFRP1 SVEP1 ASTN1	1.27e-04	200	108	5	87a5a0c252c08ba10316c21f6a9d5244c4d98c74
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SFRP1 ARHGAP15 CENPK TRPM3 MDH1B	1.27e-04	200	108	5	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	severe-Non-classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AGPAT3 SFMBT2 CYRIA GPR137B MBD2	1.27e-04	200	108	5	804c6e998fb7a29ca1b98f53d5dbcb7ae5a47e7a
ToppCell	medial-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH BOC SFRP1 SVEP1 ASTN1	1.27e-04	200	108	5	6ccf44f10d2cee5f48b8f05bd9a1b94057184d56
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CFH BOC SFRP1 SVEP1 NTM	1.27e-04	200	108	5	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	medial-mesenchymal-Adventitial_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH BOC SFRP1 SVEP1 ASTN1	1.27e-04	200	108	5	5ee1318a74ca28a81bd81c20c611de84c17636b0
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH BOC SFRP1 SVEP1 NTM	1.27e-04	200	108	5	687cfada2d0977e8985e0a73a5804f84f2ca9c52
Disease	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2	ALOXE3 ALOX12B	1.33e-05	2	108	2	242100
Disease	Autosomal recessive congenital ichthyosis 2	ALOXE3 ALOX12B	1.33e-05	2	108	2	cv:C3888093
Disease	ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1	ALOXE3 ALOX12B	1.33e-05	2	108	2	C1855792
Disease	opioid use disorder	ARHGAP15 CDKAL1 OPRM1 TMEM120A FURIN	3.58e-05	101	108	5	EFO_0010702
Disease	brother of CDO measurement	CFH BOC	3.97e-05	3	108	2	EFO_0020194
Disease	Self-Healing Collodion Baby	ALOXE3 ALOX12B	3.97e-05	3	108	2	C1855789
Disease	protein Largen measurement	CFH COPS4	3.97e-05	3	108	2	EFO_0802952
Disease	Ichthyosis Congenita I	ALOXE3 ALOX12B	7.93e-05	4	108	2	C4551630
Disease	Harlequin Fetus	ALOXE3 ALOX12B	7.93e-05	4	108	2	C0239849
Disease	netrin-1 measurement	CFH MBD1	7.93e-05	4	108	2	EFO_0022009
Disease	Ichthyosis Congenita II	ALOXE3 ALOX12B	7.93e-05	4	108	2	C3536797
Disease	Collodion Fetus	ALOXE3 ALOX12B	7.93e-05	4	108	2	C3543867
Disease	Congenital ichthyosis	ALOXE3 ALOX12B	1.32e-04	5	108	2	C0020758
Disease	secreted frizzled-related protein 1 measurement	CFH SFRP1	1.97e-04	6	108	2	EFO_0020718
Disease	Glomerulonephritis, Membranoproliferative	CFH DNASE2	2.75e-04	7	108	2	C0017662
Disease	opioid-binding protein/cell adhesion molecule measurement	CFH NTM	3.66e-04	8	108	2	EFO_0020618
Disease	DNA repair protein RAD51 homolog 4 measurement	CFH TEX14	7.14e-04	11	108	2	EFO_0801531
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	ALOXE3 ALOX12B	7.14e-04	11	108	2	C0079154
Disease	Congenital ichthyosis of skin	ALOXE3 ALOX12B	7.14e-04	11	108	2	cv:C0020758
Disease	benign prostatic hyperplasia	NUP107 MBD2	1.17e-03	14	108	2	EFO_0000284
Disease	C-C motif chemokine 19 measurement	CFH DNAJC13	1.17e-03	14	108	2	EFO_0008047
Disease	corneal resistance factor	SFRP1 ARHGAP15 CENPK TRPM3 ANAPC1 XYLB HERC2	1.38e-03	451	108	7	EFO_0010067
Disease	Spermatogenic Failure, Nonobstructive, Y-Linked	USP9Y CDY1	1.54e-03	16	108	2	C1839071
Disease	Spermatogenic failure, Y-linked, 2	USP9Y CDY1	1.54e-03	16	108	2	cv:C1839071
Disease	SPERMATOGENIC FAILURE, Y-LINKED, 2	USP9Y CDY1	1.54e-03	16	108	2	415000
Disease	sphingomyelin 14:0 measurement	TRPM3 GPR137B	1.74e-03	17	108	2	EFO_0010390
Disease	diffuse plaque measurement	ARHGAP15 C1orf167 CUL7 METTL4 DNAH14 CDKAL1 OPRM1 KAT6B NPAS2	1.89e-03	758	108	9	EFO_0010699

Protein segments in the cluster

Peptide	Gene	Start	Entry
WKICTICNELFPENV	ADNP	446	Q9H2P0
PQKQWLHLSAAQCVA	FAM210A	51	Q96ND0
KAQNITAPESEAICW	C1orf167	496	Q5SNV9
ASILPLCDLVWANEK	CDY1	396	Q9Y6F8
SILWDNCNAPKAVVL	ERVK13-1	66	Q9NX77
RIKEQVVGLLAWNNC	B4GALNT1	66	Q00973
FPTCSVEQAQWVLAK	CUEDC2	156	Q9H467
GVWTQLPQCVAIDKL	CFH	736	P08603
LSSWCNGLLQEPKIS	ASTN1	1236	O14525
LSGNLKQLLPVCDTW	NUP107	431	P57740
FCPELTTNVKALRWQ	KAT6B	251	Q8WYB5
TEICDIQQDWKPSFL	NPAS2	66	Q99743
PVVKCTIDNTLDQWL	ANAPC1	1846	Q9H1A4
DIQLQEKAWNAVCPL	CYRIA	71	Q9H0Q0
AKIINVCNWILSSAI	OPRM1	186	P35372
CTLQGKLQPEDWTSL	GPAA1	266	O43292
KWCLDPRVVLLSNTQ	NTM	81	Q9P121
LNLTQPKLAQDCWLC	ERVS71-1	291	P61550
LSPVEIECAKWLQSS	HERC2	1326	O95714
CNNLLLFWLVSQEPK	ALOXE3	636	Q9BYJ1
KVTAPQLACLLEWGQ	KIAA1109	926	Q2LD37
QRILAPCKLETVGWQ	COMMD10	126	Q9Y6G5
CSGLSWVVALPQVKQ	MBD1	486	Q9UIS9
KPWEVQSQVALLVAA	PDE6A	726	P16499
DQLVCLVLEAWQKGP	CUL7	1586	Q14999
ALPTWDKQIQSLCFQ	COPS4	366	Q9BT78
KCWAFLQESSLNPLI	HERC6	521	Q8IVU3
SVQQVGWSLLCKLIE	LRRK2	76	Q5S007
FACPTSNLQIIGLWK	NLRP5	1146	P59047
PLLKLACGNTELNQW	OR12D2	181	P58182
EEQVAWALTKFPCLQ	NSUN6	381	Q8TEA1
WALTKFPCLQLQPQE	NSUN6	386	Q8TEA1
KLPCAWVVESSGILN	HUWE1	1541	Q7Z6Z7
KSTQIPQWCAEFALA	DQX1	76	Q8TE96
PIDWLLNDIFQVKVC	MGAT4D	316	A6NG13
ARQPWKESTAFQCVL	NPHP4	21	O75161
LSVLKLACADTWVNQ	OR2A2	181	Q6IF42
AACPVLVGNKWVSNK	P4HA1	501	P13674
WLNTSQPLCKAFIVT	MBD2	351	Q9UBB5
AIQKALQPDWFQCLS	QTRT2	131	Q9H974
TSANIDLCPTNWKKI	CCNYL3	106	P0C7X3
QLVIPWGQSAKLTCE	BOC	331	Q9BWV1
ELLNSKLPRWQETCV	BAIAP2L1	216	Q9UHR4
GILPSNCSDIWQVLN	DNASE2	261	O00115
AHQTLLNKWIPTCAQ	DNAH3	396	Q8TD57
ADLWLLNSCTVKNPA	CDKAL1	101	Q5VV42
KPLIWIQRLSCSENE	FRMPD2	671	Q68DX3
ALAQNWTTVAPQRKC	FURIN	436	P09958
CLTAELSQWQKKTPE	CENPK	66	Q9BS16
QSIPQLKWCLLASGQ	DNAJC13	1021	O75165
WKNIQDLSIVAACVP	DNAH14	1966	Q0VDD8
EEEALKTCINPLQVW	MDH1B	121	Q5I0G3
PELQSWVQEIFKECL	ALOX12B	531	O75342
DLTPLQNVCFWTKTR	HASPIN	371	Q8TF76
DQLVCLVLEAWQKGP	CUL9	1891	Q8IWT3
QTANRSKAICVQWDP	CELSR3	2471	Q9NYQ7
SWNVCQELLSPKDLR	EFCAB3	381	Q8N7B9
IVTKWDLVCESQPLN	SLC22A25	131	Q6T423
KLAAPNCLLVTWVTN	METTL4	316	Q8N3J2
LAIKFDCPVNVIDNW	CPHXL	61	A0A1W2PPM1
LVNLTCAVLVKTGNW	GPR137B	171	O60478
PLSQCVQWVDDAKLN	RSBN1L	631	Q6PCB5
LCAGVTLVQWKPAQA	SLC35A1	151	P78382
LCDPANLQWFILTKA	TCAIM	391	Q8N3R3
NWAAPEVILQKAATV	TEX14	421	Q8IWB6
LTLFNLAQDPQCKEW	TMEM120A	291	Q9BXJ8
PQVTLWICGLKLQES	NBPF7P	296	P0C2Y1
AKALQECPNSGILWS	PRPF6	801	O94906
ESPLCNEALVDQLWK	TAF2	941	Q6P1X5
NPVWILTAAHCVQLK	OVCH1	606	Q7RTY7
NSTVPWFVKQCIEAV	ARHGAP15	291	Q53QZ3
LQSCSKLEDLPAEQW	SATB2	156	Q9UPW6
STVLDQQLGCLWQKD	WDR1	276	O75083
NIRDWNTKVPELCLG	SLF2	971	Q8IX21
SWVPLLNKNCHAGTQ	SFRP1	96	Q8N474
LKCLPSQQWNDSFPV	SVEP1	2361	Q4LDE5
QWCKQLFSSVVPVLL	MLXIPL	216	Q9NP71
ACVPWENKIKAIESQ	TMC1	166	Q8TDI8
EFPSLVNLCQSWKIN	APOL5	46	Q9BWW9
AIFEILEKSWLPQNC	PAICS	171	P22234
NETWELCPVKSNFSI	VPS50	466	Q96JG6
ISENCLSDPTLIWKA	TRAM1L1	141	Q8N609
PNVDTRQKQLAAWCS	VPS25	21	Q9BRG1
NCWLKGPQQELNLTA	nan	386	Q6ZTK2
ARPLIEEAALKCWQN	WDFY3	2236	Q8IZQ1
VQLCTLALWPVSKQL	AGPAT3	31	Q9NRZ7
ALATAVIPQWQKDEL	AARS1	801	P49588
ELKNWSNATCLQLAV	TRPM3	751	Q9HCF6
AISWPLLQKCNDVIN	WDHD1	171	O75717
NDVINAKSICRLAWQ	WDHD1	181	O75717
QGVICLDILKDNWSP	UBE2E3	141	Q969T4
ADSLGILPVQWCLKN	SFMBT2	351	Q5VUG0
ILPVQWCLKNGVSLT	SFMBT2	356	Q5VUG0
LLQIQDKVWSQACLG	XYLB	221	O75191
YEDLAPCITLKNWVQ	TPP2	781	P29144
LPLSLAACTKQWDVV	TRPV2	211	Q9Y5S1
LIEWLCGEAKQPVNL	VWA2	701	Q5GFL6
TNPVATLLEWQDALC	TROAP	751	Q12815
NCLTVLAARNPAKVW	NUP188	616	Q5SRE5
CELKPQQSELNSFLW	TRABD2A	31	Q86V40
LFATCLPNQTVLKIW	TBC1D30	436	Q9Y2I9
CRLVCEWAQKVLSQP	RFX7	126	Q2KHR2
PQAKQIWKCLAENAV	USP9Y	676	O00507
KCNLGRAVQLQELWP	PSME4	56	Q14997
SIEDLKAQPKQTTCW	THYN1	76	Q9P016
CNNLWLFLETGQLPK	TMEM141	86	Q96I45
SQLTEKDVNCLEPWL	YTHDC2	451	Q9H6S0
IEFSLAEWKCLNPSQ	ZNF611	31	Q8N823
QCLDWLAVQTPRNKL	USP34	2641	Q70CQ2
RWVDHLCSPQVNQKS	WDR11	1111	Q9BZH6
WALLDPSQKNLCRDV	ZNF433	21	Q8N7K0
CEDPSKLWAILNTVS	ZNF438	801	Q7Z4V0
PNIKLVLDDCWATST	ZP2	536	Q05996
CWQKVDPALCSNVLQ	TMEM39B	356	Q9GZU3
SIWTNEPLACIQVLD	KLHL32	556	Q96NJ5