Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.09e-115334GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.16e-107334GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.16e-107334GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.29e-0910334GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.29e-0910334GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.29e-0910334GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.37e-0913334GO:0016713
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.63e-0849335GO:0016712
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.42e-0824334GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.06e-0727334GO:0008391
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT2B15 UGT2B17 CYP4F2 CYP4F12 PLOD1 CYP4F11 AGRN

1.06e-07239337GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

UGT2B15 UGT2B17 CYP4F2 CYP4F12 PLOD1 CYP4F11 AGRN

1.60e-07254337GO:0043177
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11 MMACHC

2.58e-07164336GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11

2.77e-07166336GO:0005506
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.12e-0735334GO:0070330
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.42e-0740334GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11

6.93e-07194336GO:0016705
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11

8.47e-07107335GO:0033293
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.21e-06115335GO:0004497
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F12 CYP4F11

1.85e-0615333GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F12 CYP4F11

2.27e-0616333GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F12 CYP4F11

2.27e-0616333GO:0050543
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.65e-062332GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.65e-062332GO:0097259
GeneOntologyMolecularFunctionheme binding

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

5.10e-06154335GO:0020037
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4F12 CYP4F11

1.31e-0528333GO:0036041
GeneOntologyMolecularFunctionoxidoreductase activity

CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 PLOD1 CYP4F11 MMACHC

2.68e-05766338GO:0016491
GeneOntologyMolecularFunctionfatty acid binding

CYP4F2 CYP4F12 CYP4F11

2.00e-0469333GO:0005504
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4D1 ADORA1 TAAR5 OR2B2 OR4K3 PTGIR MRGPRF

5.06e-04884337GO:0004930
GeneOntologyMolecularFunctionretinoic acid binding

UGT2B15 UGT2B17

9.75e-0428332GO:0001972
GeneOntologyMolecularFunctionlipid binding

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP2R1 CYP4F11 UNC13A

9.80e-04988337GO:0008289
GeneOntologyMolecularFunctionspectrin binding

UNC13A EPB41L2

1.44e-0334332GO:0030507
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT2B15 UGT2B17

1.52e-0335332GO:0015020
GeneOntologyMolecularFunctionvitamin binding

CYP2R1 PLOD1 MMACHC

2.35e-03161333GO:0019842
GeneOntologyMolecularFunctionFAD binding

NQO2 MMACHC

2.40e-0344332GO:0071949
GeneOntologyMolecularFunctiontransition metal ion binding

CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 PLOD1 CYP4F11

2.84e-031189337GO:0046914
GeneOntologyMolecularFunctionretinoid binding

UGT2B15 UGT2B17

2.85e-0348332GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT2B15 UGT2B17

2.97e-0349332GO:0019840
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT2B15 UGT2B17 PLOD1

5.02e-03211333GO:0016758
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR4D1 ADORA1 TAAR5 OR2B2 OR4K3 PTGIR MRGPRF

5.80e-031353337GO:0004888
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

NQO2 MMACHC

1.05e-0294332GO:0050660
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT2B15 UGT2B17 PLOD1

1.18e-02288333GO:0016757
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.12e-116334GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.89e-107334GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.78e-108334GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.78e-0911334GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.66e-0912334GO:0042758
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

3.73e-093333GO:0042361
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

1.49e-084333GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

1.49e-084333GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

1.49e-084333GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

1.49e-084333GO:0042377
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 CYP4F12 NQO2 CYP4F11

3.19e-0821334GO:0042182
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.89e-0822334GO:1901569
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

7.44e-086333GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

7.44e-086333GO:0062232
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.27e-0741334GO:0006691
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

6.10e-0711333GO:0042373
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

8.13e-0712333GO:0042363
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP4F2 CYP4F12 CYP2R1 CYP4F11

1.29e-0651334GO:0006775
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F2 CYP4F12 CYP4F11

1.34e-0614333GO:0097267
GeneOntologyBiologicalProcessvitamin metabolic process

CYP4F2 CYP4F12 CYP2R1 CYP4F11 MMACHC

2.12e-06133335GO:0006766
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP2R1

2.83e-06141335GO:0006805
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

3.00e-0618333GO:0009111
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.11e-0668334GO:0019369
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.47e-0673334GO:1901616
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.70e-0682334GO:1901568
GeneOntologyBiologicalProcessnegative regulation of organic acid transport

ADORA1 SLC43A2 CYP4F2

1.79e-0532333GO:0032891
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP2R1

2.56e-05222335GO:0071466
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.43e-05116334GO:0009062
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

3.71e-056332GO:0042360
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.45e-05124334GO:0001676
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.04e-05128334GO:0033559
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B15 UGT2B17

6.91e-058332GO:0070980
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.54e-05142334GO:0006690
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.18e-05145334GO:0072329
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B15 UGT2B17

1.11e-0410332GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B15 UGT2B17

1.62e-0412332GO:0052697
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.88e-04180334GO:0120254
GeneOntologyBiologicalProcesslipid catabolic process

ADORA1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.29e-04382335GO:0016042
GeneOntologyBiologicalProcessrenal system process involved in regulation of blood volume

ADORA1 CYP4F12

3.74e-0418332GO:0001977
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B15 UGT2B17

5.11e-0421332GO:0052695
GeneOntologyBiologicalProcessnegative regulation of amino acid transport

ADORA1 SLC43A2

5.11e-0421332GO:0051956
GeneOntologyBiologicalProcesssmall molecule catabolic process

CYP4F2 CYP4F3 CYP4F12 NQO2 CYP4F11

5.12e-04421335GO:0044282
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP4F2 CYP4F12

5.62e-0422332GO:0019373
GeneOntologyBiologicalProcessregulation of organic acid transport

ADORA1 SLC43A2 CYP4F2

5.92e-04103333GO:0032890
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B15 UGT2B17

7.88e-0426332GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B15 UGT2B17

7.88e-0426332GO:0006063
GeneOntologyBiologicalProcessorganic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.96e-04272334GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.96e-04272334GO:0046395
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.48e-04731336GO:0032787
GeneOntologyBiologicalProcessketone metabolic process

CYP4F2 CYP4F12 NQO2 CYP4F11

9.84e-04279334GO:0042180
GeneOntologyBiologicalProcessrenal system process involved in regulation of systemic arterial blood pressure

ADORA1 CYP4F12

1.12e-0331332GO:0003071
GeneOntologyBiologicalProcessorganic acid metabolic process

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.25e-031064337GO:0006082
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR4D1 ADORA1 TAAR5 OR2B2 OR4K3 PTGIR AGRN MRGPRF

1.30e-031395338GO:0007186
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP2R1

1.38e-03525335GO:0009410
GeneOntologyBiologicalProcessvery long-chain fatty acid metabolic process

CYP4F2 CYP4F12

1.43e-0335332GO:0000038
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT2B15 UGT2B17

1.60e-0337332GO:0042537
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT2B15 UGT2B17

1.60e-0337332GO:0042178
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B15 UGT2B17

1.68e-0338332GO:0008209
GeneOntologyBiologicalProcessnegative regulation of amine transport

ADORA1 SLC43A2

2.15e-0343332GO:0051953
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4D1 ADORA1 PIEZO2 OR2B2 OR4K3

2.17e-03582335GO:0050906
GeneOntologyBiologicalProcessestrogen metabolic process

UGT2B15 UGT2B17

3.13e-0352332GO:0008210
GeneOntologyBiologicalProcesscellular catabolic process

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 NQO2 CYP4F11

3.18e-031253337GO:0044248
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.29e-03641335GO:1901615
GeneOntologyBiologicalProcessregulation of amino acid transport

ADORA1 SLC43A2

4.15e-0360332GO:0051955
GeneOntologyCellularComponentendoplasmic reticulum membrane

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11 AQP11

1.28e-041293339GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11 AQP11

1.33e-041299339GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11 AQP11

1.56e-041327339GO:0042175
GeneOntologyCellularComponentcalyx of Held

ADORA1 UNC13A

1.47e-0336332GO:0044305
GeneOntologyCellularComponentnuclear outer membrane

UGT2B15 UGT2B17

1.82e-0340332GO:0005640
GeneOntologyCellularComponentnuclear membrane

MRPS23 UGT2B15 UGT2B17 MRGPRF

2.13e-03349334GO:0031965
MousePhenopersistence of hyaloid vascular system

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11

3.28e-05223245MP:0001289
MousePhenoabnormal retina blood vessel morphology

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11

4.13e-05234245MP:0010097
MousePhenodecreased synaptic depression

ADORA1 UNC13A

2.18e-0413242MP:0002917
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.24e-0845325IPR002401
DomainCyt_P450_CS

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.88e-0853325IPR017972
DomainCYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.18e-0857325PS00086
Domain-

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.57e-08583251.10.630.10
Domainp450

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.57e-0858325PF00067
DomainCyt_P450

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

5.44e-0860325IPR001128
DomainUDPGT

UGT2B15 UGT2B17

5.85e-0421322PS00375
DomainUDPGT

UGT2B15 UGT2B17

5.85e-0421322PF00201
DomainUDP_glucos_trans

UGT2B15 UGT2B17

5.85e-0421322IPR002213
DomainGPCR_Rhodpsn_7TM

OR4D1 ADORA1 TAAR5 OR2B2 PTGIR MRGPRF

8.51e-04670326IPR017452
Domain7tm_1

OR4D1 ADORA1 TAAR5 OR2B2 PTGIR MRGPRF

8.98e-04677326PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4D1 ADORA1 TAAR5 OR2B2 PTGIR MRGPRF

9.54e-04685326PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4D1 ADORA1 TAAR5 OR2B2 PTGIR MRGPRF

9.99e-04691326PS50262
DomainGPCR_Rhodpsn

OR4D1 ADORA1 TAAR5 OR2B2 PTGIR MRGPRF

1.01e-03692326IPR000276
DomainMFS

SLC43A2 SLC22A10

7.68e-0377322IPR011701
DomainMFS_1

SLC43A2 SLC22A10

7.68e-0377322PF07690
DomainMFS

SLC43A2 SLC22A10

1.47e-02108322PS50850
Domain7TM_GPCR_Srsx

ADORA1 TAAR5

1.57e-02112322SM01381
DomainMFS_dom

SLC43A2 SLC22A10

2.20e-02134322IPR020846
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F12 CYP4F11 PTGIR

4.84e-0933285MM15918
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.10e-0912284MM14845
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.10e-0912284M27129
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

7.10e-09219288MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

7.36e-09220288M10320
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.23e-0814284MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.67e-0815284M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.74e-0818284MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.74e-0818284MM14841
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

4.60e-08104286M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

4.88e-08105286MM14842
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

5.21e-08183287M39588
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.27e-0762285M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.49e-0764285M5650
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.53e-0725284MM14858
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.74e-0766285MM14839
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.90e-0733284MM15963
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F12 CYP4F11

1.15e-0611283MM14863
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

1.53e-0612283M27128
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.01e-0661284MM14861
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

9.11e-0621283M27137
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F12 PTGIR

3.04e-0531283M39851
PathwayWP_TRYPTOPHAN_METABOLISM

CYP4F2 CYP4F12 CYP4F11

1.14e-0448283MM15902
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

1.36e-049282M39819
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11

2.12e-0459283M27140
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.33e-04170284MM15573
PathwayREACTOME_PREDNISONE_ADME

UGT2B15 UGT2B17

9.38e-0423282MM16639
PathwayREACTOME_GLUCURONIDATION

UGT2B15 UGT2B17

1.02e-0324282MM14599
PathwayWP_GLUCURONIDATION

UGT2B15 UGT2B17

1.11e-0325282MM15820
PathwayREACTOME_GLUCURONIDATION

UGT2B15 UGT2B17

1.11e-0325282M17787
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B15 UGT2B17

1.11e-0325282M605
PathwayWP_GLUCURONIDATION

UGT2B15 UGT2B17

1.20e-0326282M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B15 UGT2B17

1.39e-0328282M19580
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX

CYP4F2 CYP4F12

1.49e-0329282M39858
PathwayREACTOME_PARACETAMOL_ADME

UGT2B15 UGT2B17

2.69e-0339282MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B15 UGT2B17

2.97e-0341282M7399
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

AGRN EPB41L2

3.12e-0342282MM15822
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

AGRN EPB41L2

3.12e-0342282M39703
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F3 CYP2R1

3.27e-0343282MM15873
PathwayREACTOME_ASPIRIN_ADME

UGT2B15 UGT2B17

3.42e-0344282M45014
PathwayREACTOME_ASPIRIN_ADME

UGT2B15 UGT2B17

3.57e-0345282MM15694
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT2B15 UGT2B17

4.57e-0351282M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT2B15 UGT2B17

4.74e-0352282M14171
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11

4.98e-03176283M27854
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT2B15 UGT2B17

5.29e-0355282M14933
PathwayKEGG_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3

5.87e-0358282M5410
PathwayREACTOME_METABOLISM_OF_LIPIDS

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

6.86e-03620285MM15193
PathwayKEGG_RETINOL_METABOLISM

UGT2B15 UGT2B17

7.11e-0364282M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT2B15 UGT2B17

8.45e-0370282M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT2B15 UGT2B17

8.92e-0372282M9257
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.71e-13433418065749
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.01e-1163349068972
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

ADORA1 CYP4F2 CYP4F12 CYP4F11

2.35e-11733422160543
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12 CYP4F11

3.11e-09433311185557
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

3.11e-09433322665481
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

6.49e-097033515128046
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

7.77e-09533322969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12 CYP4F11

7.77e-09533321466787
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

8.73e-0723323105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

8.73e-07233217848572
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

8.73e-07233224267955
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

8.73e-07233224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

8.73e-07233218662666
Pubmed

Cytoskeletal protein 4.1G binds to the third intracellular loop of the A1 adenosine receptor and inhibits receptor action.

ADORA1 EPB41L2

8.73e-07233212974671
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

8.73e-07233222170718
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

8.73e-07233227496708
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

8.73e-0723321909870
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

8.73e-07233228228532
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

8.73e-07233232660355
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

8.73e-07233215364545
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

8.73e-07233217980168
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

8.73e-07233224121496
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

8.73e-07233215666817
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.73e-0723328026587
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

8.73e-0723323117546
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

8.73e-07233217698910
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

UGT2B15 TGM1 CYP4F2 CYP4F3 NQO2

1.05e-0619333519343046
Pubmed

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

UGT2B15 UGT2B17

2.62e-06333220736324
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B15 UGT2B17

2.62e-06333223223495
Pubmed

Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.

UGT2B15 UGT2B17

2.62e-06333226385605
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17

2.62e-06333219572376
Pubmed

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

UGT2B15 UGT2B17

2.62e-06333218302198
Pubmed

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

UGT2B15 UGT2B17

2.62e-06333228882566
Pubmed

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

UGT2B15 UGT2B17

2.62e-06333230689982
Pubmed

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

UGT2B15 UGT2B17

2.62e-06333226163549
Pubmed

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.

UGT2B15 UGT2B17

2.62e-06333217988216
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

2.62e-06333215145985
Pubmed

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

UGT2B15 UGT2B17

5.23e-06433218281521
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B15 UGT2B17

5.23e-06433226176234
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

8.72e-06533218577768
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F2 CYP4F12 CYP4F11

1.00e-054433312745259
Pubmed

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

CYP4F2 CYP4F12 CYP4F11

1.15e-054633325209997
Pubmed

Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.

UGT2B15 UGT2B17

1.31e-05633221365123
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B15 UGT2B17

1.83e-05733226074487
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT2B15 UGT2B17

2.44e-05833222579593
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B15 UGT2B17

2.44e-05833232093886
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B15 UGT2B17

2.44e-05833218719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B15 UGT2B17

2.44e-05833220142249
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

CYP4F2 CYP4F12 CYP4F11

5.22e-057633322323595
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B15 UGT2B17

5.73e-051233220308471
Pubmed

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.

PLOD1 AGRN

2.58e-042533217170699
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

SLC43A2 CYP4F12 AQP11 MRGPRF

7.10e-0443033416303743
Pubmed

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.

UGT2B15 UGT2B17 AQP11

8.62e-0419733321386911
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

ADORA1 TAAR5 PTGIR

9.00e-0420033318240029
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CYP4F2 CYP4F3 CYP4F12 MPV17L2 CYP4F11 UNC13A

1.99e-05797336chr19p13
Cytoband4q13

UGT2B15 UGT2B17

5.23e-05153324q13
Cytoband6q23

TAAR5 EPB41L2

5.97e-05163326q23
Cytoband19p13.1

CYP4F12 CYP4F11

5.54e-044833219p13.1
Cytoband19p13.11

MPV17L2 UNC13A

1.28e-037333219p13.11
CytobandEnsembl 112 genes in cytogenetic band chr17q22

MRPS23 OR4D1

1.85e-0388332chr17q22
CytobandEnsembl 112 genes in cytogenetic band chr6q23

TAAR5 EPB41L2

3.34e-03119332chr6q23
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B15 UGT2B17

5.72e-03157332chr4q13
Cytoband14q11.2

TGM1 OR4K3

7.45e-0318033214q11.2
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.25e-07362741003
GeneFamilyUDP glucuronosyltransferases

UGT2B15 UGT2B17

1.04e-0332272363
GeneFamilyOlfactory receptors, family 4

OR4D1 OR4K3

1.58e-02129272151
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11 SLC22A10

1.04e-07190326MM1311
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F2 CYP4F12 CYP4F11

1.86e-0620323MM1104
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11 SLC22A10

2.62e-06330326MM1120
CoexpressionBOCHKIS_FOXA2_TARGETS

UGT2B15 UGT2B17 CYP4F2 CYP4F12 NQO2 CYP4F11

1.89e-05467326MM1233
CoexpressionCTIP_DN.V1_DN

TGM1 CYP4F3 CYP4F12 PTGIR

2.10e-05134324M2751
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

UGT2B15 UGT2B17 CYP4F2 CYP4F12 CYP4F11 AQP11

4.06e-05535326MM3635
CoexpressionHOFFMAN_CLOCK_TARGETS_UP

UGT2B15 UGT2B17

6.46e-0510322M2063
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

UGT2B15 UGT2B17 AQP11 SLC22A10

1.02e-04201324MM1294
CoexpressionANDERSEN_LIVER_CANCER_KRT19_DN

UGT2B15 UGT2B17 CYP4F2

1.05e-0475323M424
CoexpressionZENG_GU_POST_ICB_METAGENE_39

CYP4F2 CYP4F12 XKR9 CYP4F11

1.08e-04204324MM17090
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

CYP4F2 CYP4F3 CYP4F12

1.18e-0478323M9911
CoexpressionNFE2L2.V2

CYP4F2 CYP4F3 CYP4F12 NQO2 CYP4F11

2.43e-04469325M2870
ToppCellControl-Neutrophil|Control / Disease condition and Cell class

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.25e-06126334450c01d89714feee6529680ec3ce69067a54b37c
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.25e-06126334730fc6dc740613b55e40e85334fa30330aa81c3b
ToppCellControl-Neutrophil-|Control / Disease condition and Cell class

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.25e-0612633465fff5ec2296272e94f44546606587833191dd82
ToppCellControl-Myeloid_G-Neutrophil|Control / Disease group, lineage and cell class

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.33e-06127334d4af23d621b546785a077c367c3a66c59749fc15
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.47e-061293345578a9ef85706ab6a204ff31716e781ec3893b75
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.55e-06130334124f76067a2d4448ce06158a769d0d11b0297110
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.55e-06130334cd6d8d646345b01ff0f04f776330a05b82e63bc9
ToppCellControl-Myeloid_G|Control / Disease group, lineage and cell class

UGT2B15 NIBAN1 CYP4F2 CYP4F3

2.63e-06131334d5a53431f1f1b283fb9338b8561e6381f0227c62
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UGT2B15 NIBAN1 CYP4F3

1.15e-041283339b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UGT2B15 NIBAN1 CYP4F3

1.15e-0412833358639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCellTCGA-Mesothelium|World / Sample_Type by Project: Shred V9

TGM1 PIEZO2 MRGPRF

1.21e-041303333ef1733eb57e2a9a3298ce0d65401f19e2084df1
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NIBAN1 CYP4F2 CYP4F3

1.32e-041343337b237690a3765d974f6f813ef2d01154bc23b9d6
ToppCellCOVID-19_Mild-Myeloid_G-Neutrophil|COVID-19_Mild / Disease group, lineage and cell class

NIBAN1 CYP4F2 CYP4F3

1.35e-04135333e9eb2bebb6d19c439c83f46c12ca0d676db69de8
ToppCellCOVID-19_Mild-Myeloid_G|COVID-19_Mild / Disease group, lineage and cell class

NIBAN1 CYP4F2 CYP4F3

1.57e-04142333c8aeb747ed836197265d269aa131fae172b45aec
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NIBAN1 CYP4F2 CYP4F3

1.60e-04143333974260c25dad599eea83a33e83117f7307b92a42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

1.77e-04148333f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

1.77e-041483334b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

1.77e-0414833355826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

UGT2B17 UNC13A DNAH14

1.84e-04150333b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADORA1 AQP11 DNAH14

2.27e-041613337c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 EPB41L2

2.27e-041613331b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 EPB41L2

2.39e-04164333b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 AGRN MRGPRF

2.48e-04166333dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F3 CYP4F11 UNC13A

2.48e-04166333d96c562e1483adb4cdd817b68133f03356d7279b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 EPB41L2

2.52e-04167333b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 EPB41L2

2.52e-0416733394fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 EPB41L2

2.52e-04167333eff3723fe60755272eca237459165e436e919ece
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

NIBAN1 CYP4F2 CYP4F3

2.57e-0416833304259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

2.66e-0417033399dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

2.66e-041703333a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 EPB41L2

2.66e-04170333876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 EPB41L2

2.66e-041703331f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PIEZO2 UNC13A

2.66e-04170333cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CATSPERB PIEZO2 EPB41L2

2.80e-041733337dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PIEZO2 CYP4F11 AQP11

2.90e-04175333eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PIEZO2 CYP4F11 AQP11

2.90e-04175333ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CATSPERB PTGIR MRGPRF

3.04e-0417833309475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CATSPERB PTGIR MRGPRF

3.04e-0417833335de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CATSPERB PTGIR MRGPRF

3.04e-04178333000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.04e-0417833378a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4F2 CYP4F3 NQO2

3.30e-04183333facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XKR9 CYP2R1 MMACHC

3.30e-0418333391079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|tumor_Lung / Location, Cell class and cell subclass

TGM1 PIEZO2 MRGPRF

3.35e-04184333b0a251030d127858e68cf164be158f209a4d720f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.41e-041853337092436b4db90289516ed130ade596e3021cffaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 PTGIR

3.41e-0418533351dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellCOVID_non-vent-Myeloid-Monocytic-Neutrophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NIBAN1 CYP4F2 CYP4F3

3.41e-041853332c89af7cdf5306b900a5b8ec4fdfb8210e5667ed
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 PTGIR

3.41e-04185333a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.41e-04185333a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGIR AGRN EPB41L2

3.46e-041863336568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NIBAN1 PIEZO2 PTGIR

3.46e-04186333cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellP07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADORA1 NIBAN1 MRGPRF

3.57e-041883336ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ADORA1 SLC43A2 NIBAN1

3.63e-04189333c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell3'-Adult-Distal_Rectal-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 CYP4F11 PTGIR

3.63e-04189333d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 CYP4F11 PTGIR

3.63e-041893332b5f1b4f173a224342ea4f10b193ee33b7662699
ToppCellP03-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADORA1 NIBAN1 MRGPRF

3.63e-04189333b5439ef221106f6d54434f268485e9bb17b39102
ToppCell3'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 CYP4F11 PTGIR

3.63e-0418933343e131458d8a4b120f7a5fb3d0c5650abded15f6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB PIEZO2 EPB41L2

3.68e-04190333876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PTGIR MRGPRF

3.68e-041903338cb950effc449ae59a915132ecc079be54d1acfe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.68e-0419033370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB PIEZO2 EPB41L2

3.68e-04190333be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PTGIR MRGPRF

3.68e-0419033317a73a658fb30a4322b31e38db7b240023738f29
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB PIEZO2 EPB41L2

3.68e-0419033309a8855901c3c9332dbaab3e40166485b696d0f1
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PTGIR MRGPRF

3.68e-041903335dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.74e-04191333a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

NIBAN1 PIEZO2 PTGIR

3.74e-0419133378c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 EPB41L2

3.74e-041913337b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.74e-041913331caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.74e-041913333d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PIEZO2 EPB41L2

3.74e-04191333cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.80e-041923334022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.80e-041923339093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADORA1 NIBAN1 MRGPRF

3.80e-0419233387c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.80e-04192333d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.80e-041923339333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.80e-041923339ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.92e-0419433390efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLOD1 PTGIR MRGPRF

3.92e-041943338f19e553f18c313c2a2ff9453884b9484b255d71
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.92e-04194333df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLOD1 PTGIR MRGPRF

3.92e-04194333f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGIR AGRN EPB41L2

3.92e-041943337a7406c3b021aeafde423d20290c681c3e8ea0a6
ToppCellcontrol-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 CYP4F3 NQO2

3.92e-041943332218e6677dc6781a6e4ef3a315f2298cc2cd9df2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLOD1 PTGIR MRGPRF

3.92e-0419433367fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL12 SLC43A2 AQP11

3.97e-0419533379114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.97e-04195333d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 PTGIR AGRN

3.97e-04195333815ac5dacd382b11abb32011ed1c0635b0ddc779
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 PTGIR MRGPRF

3.97e-041953331236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.97e-04195333803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 CYP4F3 DNAH14

3.97e-04195333d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NIBAN1 CYP4F3 DNAH14

3.97e-0419533319853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 PTGIR MRGPRF

3.97e-04195333b21bf50d689fc3b933182f4bfdde82f375257b72
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

3.97e-041953334f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 PTGIR MRGPRF

3.97e-04195333b5db3c0e3a41f68fca18e0a74e1b7e81df4f94c5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PTGIR MRGPRF

4.03e-041963335146976881d79642ebe5dcbcf89e0252713a9ef2
ToppCellmild-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 CYP4F3 NQO2

4.03e-041963339c351306b6aae68ed47d4cb1911957bf67f9e1ae
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 PTGIR MRGPRF

4.03e-04196333ce6f7ddb8104471dc90347f427486379914d63b4
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIBAN1 PTGIR MRGPRF

4.03e-041963336d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIEZO2 PTGIR AGRN

4.03e-0419633373f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTGIR EPB41L2

4.03e-041963332b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PTGIR MRGPRF

4.03e-04196333ebac1d6af7a5732707d82d01285c086b19d8ae62
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NIBAN1 PTGIR MRGPRF

4.09e-04197333d14e1f2ba94240c61eac435db43508a224d606a8
ComputationalNeighborhood of GSTM1

CYP4F2 CYP4F12 CYP4F11

7.41e-04109183GNF2_GSTM1
ComputationalNeighborhood of LCAT

CYP4F2 CYP4F12 CYP4F11

1.08e-03124183GNF2_LCAT
ComputationalNeighborhood of HPN

CYP4F2 CYP4F12 CYP4F11

1.35e-03134183GNF2_HPN
ComputationalNeighborhood of HPX

CYP4F2 CYP4F12 CYP4F11

1.38e-03135183GNF2_HPX
DrugAC1Q7AUJ

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.39e-10117327CID000003303
Drugdiclofenac

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11 PTGIR

3.84e-10209328CID000003032
Drughexobarbital

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.26e-10127327CID000003608
Drugdioxin

UGT2B15 UGT2B17 TGM1 CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

8.24e-10347329CID000015625
Drugaminopyrine

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.42e-09171327CID000006009
Drugbenzphetamine

UGT2B15 UGT2B17 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.46e-08119326CID000002341
Drug3 -hydroxypregn-5-en-20-one

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.36e-08238327CID000001027
Drugpropoxyphene

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.59e-0867325CID000010100
Drugcarteolol

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

5.17e-0872325CID000002583
Drugtrimipramine

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

8.82e-0880325CID000005584
Drugdiosmetin

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.20e-0785325CID005281612
Drugmephenytoin

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.43e-0788325CID000004060
Drugtienilic acid

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.88e-0793325CID000038409
Druglansoprazole

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.88e-0793325CID000003883
Drugclofibrate

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.08e-07311327CID000002796
Drugalprazolam

CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11

2.59e-07193326CID000002118
DrugAC1L1KIN

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.71e-07100325CID000005516
DrugSparteinum

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.85e-07101325CID000003966
Drugdichloran

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.14e-0741324CID000007430
DrugNADP(H

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2 CYP4F11

5.04e-07527328CID000000930
Drugphenobarbital

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

5.58e-07360327CID000004763
Drug8-MOP

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

6.18e-07118325CID000004114
Drugazo analog I

CYP4F3 CYP4F12 PTGIR

7.14e-0713323CID006438575
Drugchloral hydrate

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

9.62e-07129325CID000002707
DrugNSC9700

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11

1.01e-06578328CID000005408
Drugaminoglutethimide

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.30e-06137325CID000002145
Drugparaoxon

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.14e-06164325CID000009395
Drug2,2,2-trichloroethanol

UGT2B15 UGT2B17 CYP4F12 CYP4F11

3.27e-0673324CID000008259
DrugNSC98537

UGT2B15 UGT2B17 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.43e-06473327CID000005410
Drugfelodipine

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.64e-06169325CID000003333
Drugrifampicin

TGM1 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

3.79e-06306326CID005381226
DrugK-K-K

CYP4F2 CYP4F3 CYP4F12 CYP2R1 NQO2

4.31e-06175325CID000003823
Drugmetyrapone

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.81e-06179325CID000004174
Drugebastine

CYP4F2 CYP4F3 CYP4F12

5.68e-0625323CID000003191
Drugdeferoxamine

TGM1 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

7.29e-06343326CID000002973
Drugtolbutamide

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

7.87e-06198325CID000005505
Drugp-nitroanisole

UGT2B15 UGT2B17 CYP4F2 CYP4F12

8.23e-0692324CID000007485
Drugbeta-naphthoflavone

UGT2B15 UGT2B17 CYP4F12 CYP2R1 NQO2

8.26e-06200325CID000002361
Drug2-naphthol

UGT2B15 UGT2B17 CYP4F12 CYP4F11

8.59e-0693324CID000008663
Drugbenzo(a)pyrene

UGT2B15 UGT2B17 CYP4F12 CYP2R1 NQO2 CYP4F11

9.30e-06358326CID000002336
DrugAC1L1AL2

CYP4F2 CYP4F3 CYP4F12 PTGIR

1.99e-05115324CID000001035
Drugalpha-naphthoflavone

UGT2B15 UGT2B17 CYP4F12 CYP2R1

2.20e-05118324CID000011790
DrugAC1O5PIQ

CYP4F2 CYP4F3 CYP4F12

2.23e-0539323CID006438348
Drug6-trans-leukotriene B4

CYP4F2 CYP4F3 CYP4F12 CYP4F11 PTGIR

2.29e-05247325CID000000169
Druglorcaserin

UGT2B15 UGT2B17

2.86e-056322ctd:C506658
Drugoltipraz

UGT2B15 UGT2B17 TGM1 NQO2

3.96e-05137324CID000047318
Drug3-hydroxystearate

CYP4F2 CYP4F12

4.00e-057322CID005282907
Drugobeticholic acid

UGT2B15 CYP4F3 CYP4F12 CYP2R1 CYP4F11

4.38e-05283325ctd:C464660
Drug2 E1

UGT2B15 UGT2B17 CYP4F12 CYP2R1

4.94e-05145324CID006102788
Drugbisphenol S

PLOD1 PTGIR

5.33e-058322CID000006626
Drugoxygen

CYP4F2 CYP4F3 CYP4F12 CYP2R1 PLOD1 CYP4F11

6.00e-05499326CID000000977
DrugAC1MUNZL

CYP4F3 CYP4F12 PTGIR

6.65e-0556323CID003643892
Drughalothane

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

7.17e-05314325CID000003562
DrugAC1L1HMM

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11 PTGIR

7.23e-05516326CID000004196
Drug17-ODYA

CYP4F2 CYP4F3 CYP4F12

8.17e-0560323CID000001449
Drug18-HETE

CYP4F2 CYP4F12

8.55e-0510322CID006442778
Drugcaffeine

ADORA1 CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

1.16e-04562326CID000002519
Drug5,6-epoxyeicosatrienoic acid

CYP4F12 CYP4F11 PTGIR

1.19e-0468323CID000001778
Drug8(9)-EET

CYP4F12 CYP4F11 PTGIR

1.24e-0469323CID000001901
Drugdelta-tocopherol

TGM1 CYP4F2

1.25e-0412322CID000092094
Drug1-aminobenzotriazole

CYP4F2 CYP4F3 CYP2R1

1.35e-0471323CID000001367
Drug3-hydroxyhexadecanoic acid

CYP4F2 CYP4F12

1.48e-0413322CID000301590
Drug1T-1S

TGM1 NQO2

1.48e-0413322CID000405389
DrugHydrochlorothiazide [58-93-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ADORA1 TAAR5 CYP2R1 AGRN

1.59e-041963241487_UP
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A

ADORA1 NIBAN1 CYP4F12 OR2B2

1.71e-042003243936_UP
Drugveratraldehyde

TGM1 PLOD1

1.72e-0414322CID000008419
Drug7-BFC

CYP4F2 CYP4F12

1.72e-0414322CID000848780
DrugAC1L1F9Q

CYP4F2 CYP4F12 CYP2R1 PTGIR

1.75e-04201324CID000003144
DrugC20H32O4

CYP4F12 CYP4F11 PTGIR

1.79e-0478323CID000001440
Drugketorolac tromethamine

TGM1 PLOD1

1.99e-0415322CID000084003
Drugdiamidine

CYP4F2 CYP4F3

1.99e-0415322CID000008813
Drug7-ethoxycoumarin

UGT2B15 UGT2B17 CYP2R1

2.38e-0486323CID000035703
Drugnifedipine

CYP4F2 CYP4F3 CYP4F12 CYP2R1 CYP4F11

2.64e-04415325CID000004485
DrugAG213

ADORA1 PTGIR AGRN

2.64e-0489323CID005328803
Drug14(15)-EpETrE

CYP4F12 CYP4F11 PTGIR

2.64e-0489323CID000001431
DrugAndrostane-3,17-diol

UGT2B15 UGT2B17

2.89e-0418322ctd:D015113
DrugDK-PGD2

PLOD1 PTGIR

2.89e-0418322CID005283036
Drugpleuromutilin

CYP4F2 CYP4F12

2.89e-0418322CID000031326
DrugC1 11-32

UGT2B15 UGT2B17

2.89e-0418322CID000443077
DrugC11131

UGT2B15 UGT2B17

2.89e-0418322CID000443076
DrugAzamulinum

CYP4F2 CYP4F12

2.89e-0418322CID003086060
Drug3-methylcholanthrene

UGT2B15 UGT2B17 CYP4F12 NQO2

2.97e-04231324CID000001674
DrugAC1L1BEQ

CYP4F12 CYP4F11 PTGIR

3.00e-0493323CID000001407
Druganti-BaPDE

UGT2B15 UGT2B17 CYP4F12 CYP4F11

3.12e-04234324CID000041322
Drugimipramine

UGT2B15 ADORA1 CYP4F11 AGRN

3.17e-04235324CID000003696
DrugDB75

CYP4F2 CYP4F3

3.22e-0419322CID000126437
DrugT4-G

UGT2B15 UGT2B17

3.22e-0419322CID000152424
Drugpropafenone

CYP4F2 CYP4F12 CYP2R1

3.50e-0498323CID000004932
DrugAC1L1OBF

UGT2B15 UGT2B17

3.58e-0420322CID000032736
Drugestriol-16-glucuronide

UGT2B15 UGT2B17

3.95e-0421322CID000122281
DrugAC1L510Y

TGM1 PTGIR

4.34e-0422322CID000196040
Drug20-HETE

CYP4F2 CYP4F3 CYP4F12

4.41e-04106323CID005283157
Drugestradiol-3-glucuronide

UGT2B15 UGT2B17

4.75e-0423322CID000066651
DrugHymecromone

UGT2B15 UGT2B17

5.63e-0425322ctd:D006923
Druglithocholic acid

UGT2B15 UGT2B17 CYP2R1

5.74e-04116323CID000009903
Drug20-hydroxyleukotriene B4

CYP4F2 CYP4F3

6.09e-0426322CID000001589
Druglicochalcone A

UGT2B15 UGT2B17

6.57e-0427322ctd:C070840
DrugC14845

CYP4F12 CYP4F11

6.57e-0427322CID011954064
DrugBP-9,10-oxide

CYP4F12 CYP4F11

6.57e-0427322CID000037456
DrugAC1L1BSF

ADORA1 PTGIR

6.57e-0427322CID000001585
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

3.42e-063322EFO_0800574
DiseaseX-25937 measurement

UGT2B15 UGT2B17

6.83e-064322EFO_0800937
DiseaseX-24574 measurement

UGT2B15 UGT2B17

2.38e-057322EFO_0800897
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

3.18e-058322EFO_0800575
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

4.08e-059322EFO_0800562
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

5.10e-0510322EFO_0022090
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

6.23e-0511322EFO_0801531
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

7.47e-0512322EFO_0800291
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

8.82e-0513322EFO_0800293
DiseaseX-19141 measurement

UGT2B15 UGT2B17

8.82e-0513322EFO_0800799
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

1.03e-0414322EFO_0800283
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

1.72e-0418322EFO_0800288
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

1.93e-0419322EFO_0800362
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

2.14e-0420322EFO_0800317
DiseaseX-24947 measurement

UGT2B15 UGT2B17

2.60e-0422322EFO_0800910
Diseasemetabolite measurement

UGT2B15 UGT2B17 CYP4F2 MPV17L2 NQO2

3.19e-04560325EFO_0004725
Diseaseepiandrosterone sulfate measurement

UGT2B15 UGT2B17

3.37e-0425322EFO_0021120
Diseaseandrosterone sulfate measurement

UGT2B15 UGT2B17

5.89e-0433322EFO_0021117
Diseaseomega-6:omega-3 polyunsaturated fatty acid ratio

UGT2B15 UGT2B17

1.35e-0350322EFO_0010732
Diseaseecosanoids measurement

CYP4F2 SLC22A10

1.63e-0355322EFO_0020044
Diseasehypertension (biomarker_via_orthology)

CYP4F2 CYP4F12 CYP4F11

1.89e-03227323DOID:10763 (biomarker_via_orthology)
DiseaseLiver diseases

MRPS23 TGM1

2.78e-0372322C0023895

Protein segments in the cluster

PeptideGeneStartEntry
DRVPEYPAWFEPFVI

UNC13A

1136

Q9UPW8
FYSQEPFLEWVPCLP

CATSPERB

331

Q9H7T0
VYFNFFVWVLPPLLL

ADORA1

181

P30542
DTRIFFVNPAPPYLW

AGRN

111

O00468
WPAAQFVNFLFVPPQ

MPV17L2

151

Q567V2
VFLNCFFNWPLEPFP

SLC43A2

221

Q8N370
LPWLFTFNVKFYPPD

EPB41L2

286

O43491
FIYVWPFTNFPIDKV

OR4K3

256

Q96R72
DLVIFQFPLYWFSVP

NQO2

96

P16083
LCPFGFEVYPFQVAW

MMACHC

16

Q9Y4U1
PCPDVYWFPIFTEVA

PLOD1

551

Q02809
VFLYNAFPWIGILPF

CYP2R1

226

Q6VVX0
PTVWPDPEVYDPFRF

CYP4F11

431

Q9HBI6
PTVWPDPEVYDPFRF

CYP4F12

431

Q9HCS2
PAVWPDPEVYDPFRF

CYP4F2

431

P78329
PSRYWLPAFFFPQAF

DNAH14

3321

Q0VDD8
PAVWPDPEVYDPFRF

CYP4F3

431

Q08477
FIPCIYIYTWPFTPF

OR4D1

251

Q15615
PWLEIPPFVMFLFSY

OR2B2

21

Q9GZK3
WFDVYDAFPPLREPV

MRPS23

31

Q9Y3D9
ITPPLVFDIFIWFAY

TAAR5

281

O14804
LFWVFQIPAPFPEYV

MRGPRF

261

Q96AM1
VFFTTLPWIIYGIFP

SLC22A10

491

Q63ZE4
AFPQFFIVYWLAPSL

AQP11

231

Q8NBQ7
VVLPKEFPVYLWQPF

NIBAN1

156

Q9BZQ8
YAFNPILDPWVFILF

PTGIR

281

P43119
WLYFPDFIVRPNPVF

PIEZO2

1211

Q9H5I5
IPFSFYYPWELAIVP

PILRB

51

Q9UKJ0
FIPEFEKQYPEFPWT

TTLL12

531

Q14166
PFDPRNEIYILFNPW

TGM1

236

P22735
TYWDFEFPRPFLPNV

UGT2B15

261

P54855
TYWDFEFPRPFLPNV

UGT2B17

261

O75795
WVCPLTIFNPDYFIP

XKR9

306

Q5GH70