Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphospholipid binding

MYOF CARMIL2 NISCH SPTBN2 PAFAH2 NUMA1 KIF16B SYT5 TTPAL VPS13B

1.03e-055486510GO:0005543
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF16B KIF5B KIF5C

2.17e-0517653GO:0008574
GeneOntologyMolecularFunctionthreonine-tRNA ligase activity

TARS3 TARS2

3.12e-053652GO:0004829
GeneOntologyMolecularFunctionmicrotubule binding

BCL2L11 NUMA1 KIF16B KIF5B KIF5C PRC1 GOLGA2

6.28e-05308657GO:0008017
GeneOntologyMolecularFunctiontubulin binding

BCL2L11 NISCH NUMA1 KIF16B KIF5B KIF5C PRC1 GOLGA2

7.23e-05428658GO:0015631
GeneOntologyMolecularFunctionATP hydrolysis activity

RECQL4 KIF16B MCM7 ATP13A3 DDX43 KIF5B KIF5C

5.64e-04441657GO:0016887
GeneOntologyMolecularFunctionphosphatidylinositol binding

NISCH NUMA1 KIF16B SYT5 TTPAL VPS13B

5.65e-04316656GO:0035091
GeneOntologyMolecularFunctionlipid binding

MYOF CARMIL2 NISCH SPTBN2 PAFAH2 NUMA1 KIF16B SYT5 TTPAL VPS13B

1.26e-039886510GO:0008289
GeneOntologyMolecularFunctionmetalloexopeptidase activity

CPXM2 XPNPEP2 CPN1

1.54e-0370653GO:0008235
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF16B KIF5B KIF5C

1.54e-0370653GO:0003777
GeneOntologyBiologicalProcessthreonyl-tRNA aminoacylation

TARS3 TARS2

2.75e-053632GO:0006435
GeneOntologyCellularComponentcentriolar satellite

CDC42BPG MYOF ZMYND10 KIF5B CCDC57 IL4R

2.63e-06128646GO:0034451
GeneOntologyCellularComponentspindle

KAT5 HECW2 CEP250 NUMA1 KIF16B PRC1 CCDC57 GOLGA2

9.17e-05471648GO:0005819
GeneOntologyCellularComponentcentrosome

CDC42BPG MYOF ZMYND10 CROCC2 CEP250 NUMA1 KIF5B CCDC57 IL4R AXIN2

1.09e-047706410GO:0005813
GeneOntologyCellularComponentmicrotubule

BCL2L11 NUMA1 KIF16B KIF5B KIF5C PRC1 CCDC57 GOLGA2

2.14e-04533648GO:0005874
GeneOntologyCellularComponentmitotic spindle

KAT5 HECW2 NUMA1 PRC1 GOLGA2

3.76e-04201645GO:0072686
GeneOntologyCellularComponentrecycling endosome membrane

SYT5 ATP13A3 VPS13B STX6

3.87e-04112644GO:0055038
GeneOntologyCellularComponentspindle pole

KAT5 CEP250 NUMA1 PRC1 GOLGA2

4.12e-04205645GO:0000922
GeneOntologyCellularComponentmicrotubule organizing center

CDC42BPG MYOF ZMYND10 CROCC2 CEP250 NUMA1 KIF5B CCDC57 IL4R AXIN2

4.50e-049196410GO:0005815
GeneOntologyCellularComponentkinesin complex

KIF16B KIF5B KIF5C

4.56e-0449643GO:0005871
GeneOntologyCellularComponentMCM complex

TONSL MCM7

4.99e-0411642GO:0042555
GeneOntologyCellularComponentrecycling endosome

NISCH SYT5 ATP13A3 VPS13B STX6

5.92e-04222645GO:0055037
GeneOntologyCellularComponentciliary rootlet

KIF5B KIF5C

1.08e-0316642GO:0035253
GeneOntologyCellularComponentmitotic spindle midzone

NUMA1 PRC1

1.08e-0316642GO:1990023
GeneOntologyCellularComponentspindle pole centrosome

CEP250 NUMA1

1.53e-0319642GO:0031616
GeneOntologyCellularComponentGolgi membrane

TLCD3B SPTBN2 COPB2 USP32 CHSY1 GOLGA2 VPS13B STX6

1.55e-03721648GO:0000139
GeneOntologyCellularComponentendoplasmic reticulum-Golgi intermediate compartment membrane

PIEZO1 GOLGA2 VPS13B

1.97e-0381643GO:0033116
GeneOntologyCellularComponentspindle microtubule

NUMA1 PRC1 CCDC57

2.34e-0386643GO:0005876
DomainCarboxyPept-like_regulatory

TENM4 CPXM2 CPN1

2.29e-0517623IPR008969
DomainThrRS_core

TARS3 TARS2

3.25e-053622IPR033728
DomainThr-tRNA-ligase_IIa

TARS3 TARS2

3.25e-053622IPR002320
DomainTGS

TARS3 TARS2

1.61e-046622IPR004095
DomainTGS

TARS3 TARS2

1.61e-046622PF02824
DomainTGS-like

TARS3 TARS2

2.25e-047622IPR012676
DomaintRNA_SAD

TARS3 TARS2

2.25e-047622SM00863
DomaintRNA_SAD

TARS3 TARS2

2.25e-047622IPR012947
DomaintRNA_SAD

TARS3 TARS2

2.25e-047622PF07973
DomainThr/Ala-tRNA-synth_IIc_edit

TARS3 TARS2

3.00e-048622IPR018163
DomainKinesin_motor_CS

KIF16B KIF5B KIF5C

3.39e-0441623IPR019821
DomainHGTP_anticodon

TARS3 TARS2

3.85e-049622PF03129
DomainKinesin-like_fam

KIF16B KIF5B KIF5C

3.91e-0443623IPR027640
DomainKINESIN_MOTOR_1

KIF16B KIF5B KIF5C

4.19e-0444623PS00411
Domain-

KIF16B KIF5B KIF5C

4.19e-04446233.40.850.10
DomainKinesin_motor_dom

KIF16B KIF5B KIF5C

4.19e-0444623IPR001752
DomainKinesin

KIF16B KIF5B KIF5C

4.19e-0444623PF00225
DomainKINESIN_MOTOR_2

KIF16B KIF5B KIF5C

4.19e-0444623PS50067
DomainKISc

KIF16B KIF5B KIF5C

4.19e-0444623SM00129
Domainaa-tRNA-synt_IIb

TARS3 TARS2

5.85e-0411622IPR002314
DomaintRNA-synt_2b

TARS3 TARS2

5.85e-0411622PF00587
Domain-

TARS3 TARS2

5.85e-04116223.40.50.800
DomainCarboxyPept_regulatory_dom

CPXM2 CPN1

8.26e-0413622IPR014766
Domain-

CPXM2 CPN1

8.26e-04136222.60.40.1120
DomainBeta-grasp_dom

TARS3 TARS2

9.62e-0414622IPR012675
Domain-

TARS3 TARS2

9.62e-04146223.10.20.30
DomainAnticodon-bd

TARS3 TARS2

9.62e-0414622IPR004154
DomainZn_pept

CPXM2 CPN1

1.60e-0318622SM00631
Domainaa-tRNA-synth_II

TARS3 TARS2

1.60e-0318622IPR006195
DomainAA_TRNA_LIGASE_II

TARS3 TARS2

1.60e-0318622PS50862
DomainCARBOXYPEPT_ZN_2

CPXM2 CPN1

1.79e-0319622PS00133
DomainCARBOXYPEPT_ZN_1

CPXM2 CPN1

1.98e-0320622PS00132
DomainPeptidase_M14

CPXM2 CPN1

2.62e-0323622PF00246
DomainPeptidase_M14

CPXM2 CPN1

2.62e-0323622IPR000834
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC42BPG ZNHIT6 ARHGAP23 NISCH RECQL4 TONSL MTR TARS2 ZC3H7B GOLGA2

4.62e-07650671038777146
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

CEP250 NUMA1 NCAPD2 MCM7 AXIN2

1.64e-0610267520508983
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CROCC2 SPTBN2 USP32 NUMA1 NCAPD2 PRPF8 CCDC57 GOLGA2

5.12e-0649767836774506
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

KAT5 WIZ NISCH RECQL4 COPB2 NCAPD2 CHSY1 KIF5B PRC1 PRPF8

5.46e-06857671025609649
Pubmed

Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.

SYT5 GOLGA2 STX6

6.48e-061967314622145
Pubmed

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.

KIF5B KIF5C

1.10e-05367217693257
Pubmed

Endosomal sorting drives the formation of axonal prion protein endoggresomes.

KIF5B KIF5C

1.10e-05367234936461
Pubmed

Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks.

NUMA1 PRC1

1.10e-05367224725408
Pubmed

Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.

KIF5B KIF5C

1.10e-0536727514426
Pubmed

Conductin/axin2 and Wnt signalling regulates centrosome cohesion.

CEP250 AXIN2

1.10e-05367220300119
Pubmed

Tip60 interacts with human interleukin-9 receptor alpha-chain.

KAT5 IL4R

1.10e-05367210486269
Pubmed

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.

KIF5B KIF5C

1.10e-05367230068641
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

CARMIL2 FARP1 SPTBN2 USP32 KIF16B ATP13A3 VPS13B STX6

1.37e-0556967830639242
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF16B KIF5B KIF5C

1.52e-05256739275178
Pubmed

GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.

KIF5B KIF5C

2.19e-05467215644324
Pubmed

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites.

KIF5B KIF5C

2.19e-05467211986669
Pubmed

KIF5C, a novel neuronal kinesin enriched in motor neurons.

KIF5B KIF5C

2.19e-05467210964943
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

HECW2 COPB2 NUMA1 KIF16B MTR MCM7

3.19e-0531367638270169
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

COPB2 NUMA1 NCAPD2 BOP1 MCM7 KIF5C TARS2 PRPF8

3.19e-0564167836057605
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

NAA25 TCHH COPB2 TONSL MTR BOP1 MCM7 KIF5B KIF5C PRPF8 PCBD1

3.21e-051284671117353931
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CEP250 SPTBN2 NUMA1 NCAPD2 MCM7 KIF5B KIF5C PRC1 PRPF8

3.49e-0584767935235311
Pubmed

Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility.

KIF5B KIF5C

3.64e-05567221750526
Pubmed

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.

KIF5B KIF5C

3.64e-0556727528108
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

COPB2 NUMA1 NCAPD2 KIF5B PRC1 PRPF8

4.42e-0533267632786267
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

PIEZO1 NUMA1 NCAPD2 BOP1 PRC1

5.45e-0521067516565220
Pubmed

Chromosomal localization reveals three kinesin heavy chain genes in mouse.

KIF5B KIF5C

5.46e-0566729782088
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HECW2 PIEZO1 KIF16B NCAPD2 CHSY1 BOP1 ZC3H7B

7.16e-0552967714621295
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

URI1 NISCH COPB2 MCM7 TARS2 CCDC57

7.24e-0536367625036637
Pubmed

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule.

KIF5B KIF5C

7.63e-05767215312650
Pubmed

mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1.

KIF5B KIF5C

7.63e-05767220019668
Pubmed

Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.

KIF5B KIF5C

7.63e-05767221335237
Pubmed

Analysis of Kif5b expression during mouse kidney development.

KIF5B KIF5C

7.63e-05767225885434
Pubmed

Defining the membrane proteome of NK cells.

CARMIL2 NISCH RECQL4 NCAPD2 CHSY1 TTPAL MCM7 ATP13A3 KIF5B PRPF8

7.65e-051168671019946888
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

ZNHIT6 SPTBN2 COPB2 NUMA1 BOP1 MCM7 KIF5B PRC1 PRPF8

8.36e-0594967936574265
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TARS3 TENM4 CARMIL2 ARHGAP23 HECW2 FARP1 NISCH SPTBN2 COPB2 KIF5B KIF5C

8.50e-051431671137142655
Pubmed

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.

RECQL4 MCM7

1.02e-04867219805216
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

FAM184B FARP1 PIEZO1 NISCH SPTBN2 KIF16B MTR BOP1 TARS2 PRPF8 VPS13B

1.19e-041487671133957083
Pubmed

Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.

KIF5B KIF5C

1.30e-0496729624122
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

KIF5B KIF5C

1.30e-04967211553612
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

KIF5B KIF5C

1.30e-04967217887960
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CDC42BPG MYOF COPB2 NUMA1 MCM7 KIF5B PRPF8 PCBD1 GOLGA2 AXIN2

1.31e-041247671027684187
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

MYOF ZNF33B CPXM2 KIF5B CPN1 PCBD1

1.50e-0441567616385451
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

NCAPD2 KIF5B KIF5C TARS2 PRC1 PRPF8 GOLGA2 AXIN2

1.61e-0480967832129710
Pubmed

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

TONSL MCM7

1.63e-041067221055985
Pubmed

Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.

KIF5B KIF5C

1.63e-041067221976701
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

MYOF COPB2 NUMA1 MCM7 KIF5B TARS2 PRPF8

1.67e-0460767739147351
Pubmed

MRE11 complex links RECQ5 helicase to sites of DNA damage.

RECQL4 MCM7

1.99e-041167219270065
Pubmed

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

KAT5 WIZ TONSL NUMA1

2.01e-0414967425184681
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

ZMYND10 ATP13A3 FCN3

2.38e-046267316641997
Pubmed

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.

KIF5B KIF5C

2.38e-041267215834408
Pubmed

The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.

KIF5B KIF5C

2.38e-041267216018997
Pubmed

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.

KIF5B KIF5C

2.38e-041267216301330
Pubmed

Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.

NUMA1 NCAPD2 PRC1

2.50e-046367334718347
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ARHGAP23 RECQL4 COPB2 NUMA1 NCAPD2 BOP1 MCM7 DDX43 KIF5B PRPF8

2.53e-041353671029467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SPTBN2 COPB2 NUMA1 NCAPD2 BOP1 KIF5B PRPF8

2.61e-0465367722586326
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYOF WIZ BCL2L11 PIEZO1 NISCH NCAPD2 CHSY1 ZC3H7B IL4R

2.61e-04110567935748872
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

COPB2 MCM7 KIF5B

3.71e-047267336376293
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ARHGAP23 FARP1 NISCH COPB2 NUMA1 MCM7 PRC1 PCBD1

3.71e-0491667832203420
Pubmed

Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply.

TONSL MCM7

3.78e-041567222407294
Pubmed

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication.

RECQL4 MCM7

3.78e-041567219696745
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

COPB2 NUMA1 NCAPD2 MTR BOP1 MCM7 KIF5B TARS2 PRC1 PRPF8

3.82e-041425671030948266
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

COPB2 NUMA1 MCM7 KIF5B KIF5C ZC3H7B PRPF8

4.10e-0470467729955894
Pubmed

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

NUMA1 NCAPD2 KIF5B

4.18e-047567329459360
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

NISCH USP32 KIF16B GOLGA2 VPS13B STX6

4.25e-0450467634432599
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

COPB2 NUMA1 BOP1 MCM7 PRPF8

4.45e-0433067532529326
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NAA25 NISCH COPB2 NCAPD2 MTR CHSY1 KIF5B TARS2

4.47e-0494267831073040
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

MYOF FARP1 NUMA1 MCM7 PRPF8

4.58e-0433267537433992
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYOF WIZ FARP1 COPB2 BOP1 PRC1 PRPF8

4.85e-0472467736232890
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

WIZ FARP1 NISCH SPTBN2 NUMA1 KIF5B KIF5C GOLGA2

5.16e-0496367828671696
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CDC42BPG WIZ HECW2 SPTBN2 RECQL4 COPB2 PRPF8

5.34e-0473667729676528
Pubmed

p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.

GOLGA2 STX6

5.48e-041867215800058
Pubmed

Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.

GOLGA2 STX6

5.48e-041867220230794
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

NUMA1 NCAPD2 MCM7 PRPF8

5.57e-0419567419454010
Pubmed

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

XPNPEP2 CPN1

6.12e-041967221052031
Pubmed

Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.

WIZ AXIN2

6.12e-041967234150743
Pubmed

Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.

GOLGA2 STX6

6.12e-041967217003038
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYOF NUMA1 NCAPD2 PRPF8

6.36e-0420267433005030
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYOF SPTBN2 NUMA1 BOP1 MCM7 KIF5B PRC1 PRPF8 GOLGA2

6.64e-04125767936526897
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

WIZ SPTBN2 NUMA1 NCAPD2 MCM7 KIF5B

6.65e-0454967638280479
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

KAT5 COPB2 NUMA1 NCAPD2 BOP1 MCM7 PRC1 PRPF8

7.24e-04101467832416067
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

COPB2 GOLGA2

7.50e-042167237422473
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

COPB2 NCAPD2 MTR BOP1 MCM7 KIF5B

8.16e-0457167637167062
Pubmed

Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.

NCAPD2 MCM7 PRC1

8.33e-049567321440680
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

WIZ NUMA1 MCM7 PRPF8

8.74e-0422067435785414
Pubmed

Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.

KAT5 BCL2L11

9.01e-042367230655546
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

URI1 ARHGAP23 NUMA1 KIF5B PRPF8

9.44e-0439067517643375
Pubmed

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.

TCHH AXIN2

9.82e-042467219165927
Pubmed

Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.

GOLGA2 AXIN2

9.82e-042467224161848
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

WIZ TONSL NUMA1 BOP1 MCM7

9.88e-0439467527248496
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

TENM4 NISCH SPTBN2

1.02e-0310267321926972
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

MYOF FARP1 NCAPD2 MCM7 KIF5B

1.04e-0339967537536630
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

NCAPD2 KIF5B KIF5C PRPF8

1.05e-0323167436597993
Pubmed

Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor.

CPXM2 AXIN2

1.07e-032567232541007
Pubmed

Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.

MTR PRC1

1.07e-032567211110696
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CEP250 NUMA1 PRPF8 VPS13B

1.10e-0323467436243803
Pubmed

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

MCM7 KIF5B PRPF8 GOLGA2

1.22e-0324167423125841
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

WIZ BOP1 MCM7

1.24e-0310967333554859
Pubmed

Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease.

GOLGA2 STX6

1.24e-032767227256505
Pubmed

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

KAT5 KIF16B NCAPD2 MCM7 GOLGA2

1.30e-0341967527107012
Pubmed

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

NCAPD2 MCM7 PRPF8

1.31e-0311167332683582
InteractionUBXN6 interactions

CDC42BPG ZNHIT6 USP32 TONSL NCAPD2 MTR ZC3H7B GOLGA2 VPS13B

1.24e-06325679int:UBXN6
InteractionEEF1AKMT3 interactions

CDC42BPG ZNHIT6 USP32 TONSL NCAPD2 MTR ZC3H7B GOLGA2 VPS13B

3.15e-06364679int:EEF1AKMT3
InteractionCCDC150 interactions

CCDC150 PRC1 GOLGA2

9.81e-0613673int:CCDC150
InteractionNSMCE1 interactions

TCHH ZNHIT6 RECQL4 NCAPD2

1.14e-0542674int:NSMCE1
InteractionDNAJC5 interactions

FARP1 PIEZO1 NISCH SPTBN2 KIF16B SYT5 TTPAL STX6

3.53e-05378678int:DNAJC5
InteractionH3-3B interactions

KAT5 WIZ TONSL NUMA1 MCM7

3.87e-05114675int:H3-3B
InteractionMCM7 interactions

CEP250 RECQL4 COPB2 TONSL NUMA1 MCM7 PRC1 GOLGA2

6.70e-05414678int:MCM7
InteractionMCM4 interactions

RECQL4 COPB2 TONSL NUMA1 NCAPD2 MCM7 PRC1

6.93e-05306677int:MCM4
InteractionFBXO22 interactions

CROCC2 SPTBN2 RECQL4 USP32 NUMA1 NCAPD2 PRPF8 CCDC57 GOLGA2

7.15e-05540679int:FBXO22
InteractionTMED5 interactions

RECQL4 COPB2 ATP13A3 PRC1

7.30e-0567674int:TMED5
Cytoband8q24.3

RECQL4 TONSL BOP1 TIGD5

2.37e-051136748q24.3
Cytoband11q13

KAT5 SPTBN2 NUMA1

7.03e-0411867311q13
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF16B KIF5B KIF5C

1.77e-0446433622
GeneFamilyCarboxypeptidases

CPXM2 CPN1

1.13e-03214321321
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

CDC42BPG ARHGAP23 FARP1 SPTBN2

1.43e-03206434682
CoexpressionHALLMARK_MITOTIC_SPINDLE

BCL2L11 FARP1 CEP250 NUMA1 KIF5B PRC1

1.21e-05199676M5893
CoexpressionGSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP

FARP1 NUMA1 KIF16B KIF5C ZC3H7B STX6

1.24e-05200676M6549
CoexpressionGSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP

TCHH BCL2L11 PIEZO1 TTPAL VPS13B STX6

1.24e-05200676M8491
ToppCell10x5'-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

CDC42BPG RECQL4 NCAPD2 CCDC150 SYT5 MCM7

1.32e-0715667663b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLCD3B ZMYND10 CROCC2 RECQL4 CCDC150 SYT5

5.54e-0719967692778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TLCD3B TCHH ZMYND10 RECQL4 SYT5

3.94e-06157675410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7|TCGA-Kidney / Sample_Type by Project: Shred V9

CDC42BPG ZMYND10 CCDC57 CNTN6 AXIN2

5.17e-06166675b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCHH ZMYND10 RECQL4 SYT5 MSLN

5.80e-06170675f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RECQL4 TONSL NCAPD2 MCM7 PRC1

5.97e-061716751eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell390C-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CARMIL2 USP32 TONSL NCAPD2 FCN3

7.45e-061796753edcd1356e49b1f5514c585861999e079ca5e579
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

CARMIL2 USP32 TONSL NCAPD2 FCN3

7.45e-06179675e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCelldroplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B ARHGAP23 MCM7 PRC1 CCDC57

9.21e-06187675c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TLCD3B TCHH RECQL4 SYT5 MCM7

9.95e-06190675250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCHH ZMYND10 CROCC2 SYT5 MSLN

9.95e-061906750adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCHH ZMYND10 CROCC2 SYT5 MSLN

9.95e-0619067505455775845f4ded5c27e7b83242078d23162aaf
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCHH RECQL4 SYT5 MCM7 PRC1

1.07e-05193675b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

MYOF CHSY1 FCN3 IL4R PDZRN4

1.10e-05194675e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF NCAPD2 MCM7 ATP13A3 PRC1

1.10e-05194675effd38e51062b225ecabc7e1c50154e65495d559
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TONSL NCAPD2 MTR MCM7 PRC1

1.16e-0519667536ed1918f70b6f5760bb088b15ce422998055cc7
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RECQL4 NCAPD2 CCDC150 MCM7 PRC1

1.21e-05198675281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCellBiopsy_Other_PF-Epithelial-Proliferating_Epithelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

RECQL4 TONSL NCAPD2 MCM7 PRC1

1.24e-05199675d73667e2e93026d95184e24ff0bc90afd1fb74a9
ToppCellBiopsy_IPF-Epithelial-Proliferating_Epithelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

RECQL4 TONSL NCAPD2 MCM7 PRC1

1.27e-0520067563c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

ZMYND10 SPTBN2 CCDC150 SYT5

6.77e-05145674ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCellBAL-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

CDC42BPG RECQL4 MCM7 PRC1

8.56e-051546740121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 HECW2 FCN3 IL4R

9.68e-05159674d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 TONSL CCDC150 PRC1

1.09e-0416467425758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 TONSL CCDC150 PRC1

1.09e-041646741642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

NAA25 BCL2L11 TONSL SYT5

1.17e-041676741e2fc1637769405a61f4c7e44945712a1888a299
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN2 CCDC150 MSLN PDZRN4

1.17e-041676741adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN2 CCDC150 MSLN PDZRN4

1.17e-04167674743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WIZ ARHGAP23 PAFAH2 TONSL

1.20e-04168674b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYOF TCHH NCAPD2 PRC1

1.31e-0417267429c8510f26527d487d0fc3543102d067cdb281a6
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

RECQL4 NCAPD2 MCM7 PRC1

1.37e-04174674e4c8da80eca07e4396f57dad212f76c2eca4c1bd
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TLCD3B RECQL4 MCM7 PRC1

1.40e-041756746b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCellNS-critical-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCHH RECQL4 SYT5 MSLN

1.43e-041766747cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SPTBN2 SYT5

1.43e-04176674bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYOF TARS3 MCM7 ATP13A3

1.43e-04176674450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SPTBN2 SYT5

1.43e-041766743c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH SPTBN2 TONSL CPN1

1.46e-04177674b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH SPTBN2 TONSL CPN1

1.46e-04177674e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FAM184B TARS3 BCL2L11 STX6

1.49e-041786748151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTR MCM7 DDX43 PRC1

1.53e-041796749dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B SYT5 DDX43 KIF5C

1.53e-04179674228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 SPTBN2 MTR CHSY1

1.53e-04179674d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

MYOF CHSY1 IL4R PDZRN4

1.53e-04179674e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 XPNPEP2 CNTN6 MSLN

1.56e-0418067447e345359064dc8ceec982b062e47802e728b43f
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 XPNPEP2 CNTN6 MSLN

1.56e-041806743d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B SYT5 KIF5C CNTN6

1.56e-041806747d3d5608647b6e684e8e185993d106a38c53e76a
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCHH NCAPD2 ATP13A3 PRC1

1.56e-0418067443fd5c498a87bb078d101298b472656f3294686a
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B TONSL SYT5 TIGD5

1.59e-04181674709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYOF ATP13A3 PRC1 CCDC57

1.63e-0418267421dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

SPTBN2 PRC1 ZNF682 GOLGA2

1.63e-04182674af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD2 MCM7 DDX43 PRC1

1.66e-04183674769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RECQL4 NCAPD2 MCM7 PRC1

1.66e-041836746c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

CPXM2 CHSY1 IL4R PDZRN4

1.66e-0418367446be9f96755c7b65aeac061d95d15abeb6466034
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD2 MCM7 DDX43 PRC1

1.66e-04183674aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

1.73e-04185674110d5f02759c8235b14aea524ea47199696094ea
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCAPD2 MCM7 DDX43 PRC1

1.73e-0418567489b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCAPD2 MCM7 DDX43 PRC1

1.73e-041856740e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TLCD3B SYT5 KIF5C PDZRN4

1.73e-04185674512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

1.73e-0418567494d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

1.77e-0418667418fd311252299d6d30ddb32002ed069056108206
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B SPTBN2 KIF5B KIF5C

1.77e-04186674a1ab273b01971d6a892912560d387685dd657179
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B SPTBN2 KIF5B KIF5C

1.81e-04187674ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CPXM2 ARHGAP23 FCN3 PDZRN4

1.81e-04187674febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

1.84e-04188674bd091503f580dedab40e0996273101285d24b586
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TONSL NCAPD2 MCM7 PRC1

1.84e-041886740ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell10x5'-Liver-Lymphocytic_NK-Cycling_NK|Liver / Manually curated celltypes from each tissue

RECQL4 NCAPD2 MCM7 PRC1

1.84e-041886745eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CPXM2 HECW2 CHSY1 FCN3

1.84e-041886740824d567356d360fd8e78e840c30529c139f98a1
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RECQL4 NCAPD2 CCDC150 PRC1

1.88e-041896741e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCHH RECQL4 MCM7 MSLN

1.92e-041906747be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

MYOF CHSY1 IL4R PDZRN4

1.92e-041906744e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TLCD3B SYT5 KIF5C PDZRN4

1.92e-04190674b4dfc41f5a630140cab8b1b86de85de0f5b25e4a
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_NE_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SYT5 KIF5C CPN1 PCBD1

1.96e-04191674f0a81f621e63e87ff62224b33cf0c71dfac1d6e2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF CHSY1 ATP13A3 IL4R

2.00e-041926748b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

2.00e-04192674307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RECQL4 NCAPD2 MCM7 PRC1

2.04e-04193674cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

CPXM2 ARHGAP23 HECW2 FCN3

2.08e-041946749591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RECQL4 NCAPD2 MCM7 PRC1

2.08e-04194674f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RECQL4 NCAPD2 MCM7 PRC1

2.08e-04194674a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

RECQL4 NCAPD2 MCM7 PRC1

2.08e-04194674a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RECQL4 TONSL MCM7 PRC1

2.08e-041946744c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RECQL4 NCAPD2 MCM7 PRC1

2.08e-0419467417744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TCHH ZMYND10 SYT5 MSLN

2.08e-041946745dffa578149104dda33774361e9e77b227b5f1ce
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TCHH RECQL4 SYT5 MCM7

2.08e-04194674dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

RECQL4 NCAPD2 MCM7 PRC1

2.08e-041946749bbb124001fba7450f4639f47f9b720a483e7242
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RECQL4 NCAPD2 MCM7 PRC1

2.08e-04194674e14f66f7584909621b776292fbd52808273fd2ee
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

TLCD3B RECQL4 MCM7 PRC1

2.12e-04195674957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYOF NCAPD2 MCM7 PRC1

2.12e-04195674c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZMYND10 CROCC2 RECQL4 SYT5

2.12e-04195674e525b69145059b66417589601f7109af63730f3a
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

2.12e-041956745a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCellHealthy-T/NK_proliferative|Healthy / disease group, cell group and cell class

TLCD3B CCDC150 MCM7 PRC1

2.16e-0419667491e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NCAPD2 CCDC150 MCM7 PRC1

2.16e-041966741d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

RECQL4 NCAPD2 MCM7 PRC1

2.16e-041966747b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

2.16e-0419667436b4f08fc038dfde6343ff0869e1a027d882adb5
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NCAPD2 CCDC150 MCM7 PRC1

2.20e-041976748b616cde333bdbc0c591035ad9e4949155866245
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

TLCD3B RECQL4 MCM7 PRC1

2.20e-04197674189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FARP1 MCM7 KIF5B PRC1

2.20e-04197674196eaecef7003ed83f323c1f157c6a3594650097
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B CARMIL2 SYT5 KIF5C

2.20e-04197674b9478212f14b7888e3abac02995177974ac3bd17
ToppCellMild-Lymphoid-T-Proliferating_T|Mild / Condition, Lineage, Cell class and cell subclass

TLCD3B RECQL4 MCM7 PRC1

2.20e-04197674794517c70089da109f4c6489fe406c0ba6882b76
ToppCellHealthy-T/NK_proliferative|World / disease group, cell group and cell class

TLCD3B NCAPD2 CCDC150 MCM7

2.20e-04197674e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLCD3B ZMYND10 CROCC2 SYT5

2.20e-041976746e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYOF ARHGAP23 MCM7 PRC1

2.20e-041976742430f31d9312338e0ca23bfc6bdb0365340860fd
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; HL60; HT_HG-U133A

MYOF KAT5 WIZ ATP13A3 KIF5B ZC3H7B GOLGA2 STX6

1.24e-071996781295_DN
Drugrosiglitazone; Down 200; 10uM; PC3; HT_HG-U133A

MYOF WIZ FARP1 CEP250 NUMA1 NCAPD2

2.23e-051936761233_DN
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; HL60; HT_HG-U133A

BCL2L11 PIEZO1 NUMA1 TTPAL ATP13A3 ZC3H7B

2.36e-051956762470_DN
DrugIodixanol [92339-11-2]; Down 200; 2.6uM; HL60; HT_HG-U133A

BCL2L11 CEP250 TTPAL DDX43 ZC3H7B VPS13B

2.57e-051986763023_DN
DrugSulmazole [73384-60-8]; Up 200; 14uM; HL60; HT_HG-U133A

MYOF BCL2L11 KIF5C ZC3H7B CCDC57 GOLGA2

2.65e-051996762153_UP
Drugazathioprine, USP; Down 200; 100uM; MCF7; HG-U133A

WIZ ZMYND10 FARP1 PAFAH2 ATP13A3 VPS13B

2.72e-05200676338_DN
Diseaseamino acid metabolic disorder (implicated_via_orthology)

TARS3 TARS2

2.77e-054642DOID:9252 (implicated_via_orthology)
Diseasehereditary spastic paraplegia (implicated_via_orthology)

ATP13A3 KIF5B KIF5C

1.13e-0443643DOID:2476 (implicated_via_orthology)
Diseasespinal muscular atrophy (implicated_via_orthology)

KIF5B KIF5C

1.65e-049642DOID:12377 (implicated_via_orthology)
Diseasemotor neuron disease (implicated_via_orthology)

KIF5B KIF5C

3.01e-0412642DOID:231 (implicated_via_orthology)
Diseasepancreatic ductal carcinoma (is_marker_for)

MCM7 IL4R MSLN

3.20e-0461643DOID:3587 (is_marker_for)
Diseaseneutrophil percentage of granulocytes

LINC01565 TLCD3B BCL2L11 ZC3H7B

1.53e-03228644EFO_0007994
Diseaseretinitis pigmentosa (implicated_via_orthology)

CEP250 PRPF8

1.57e-0327642DOID:10584 (implicated_via_orthology)
Diseaseeosinophil percentage of granulocytes

LINC01565 TLCD3B BCL2L11 ZC3H7B

1.69e-03234644EFO_0007996
Diseasereticulocyte count

LINC01565 KAT5 BCL2L11 PIEZO1 NISCH USP32 PRPF8 PCBD1

1.84e-031045648EFO_0007986
Diseasebasophil count, eosinophil count

LINC01565 BCL2L11 ZC3H7B IL4R

1.88e-03241644EFO_0004842, EFO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
LLSEEERLAWEQQEP

BOP1

321

Q14137
ERLAWEQQEPGERKL

BOP1

326

Q14137
LTLLRDEEREVNPWQ

NKAPP1

106

Q8N9T2
DGLDLWGIQRVENAR

ATP13A3

506

Q9H7F0
DWDNTELIRRIEIQP

COPB2

451

P35606
KRLIQQDRLWAPEED

CARMIL2

1066

Q6F5E8
ERERDDELRQGWLLQ

LINC01565

81

O15544
IWIAQELRRIGDEFN

BCL2L11

146

O43521
LQLPREEGDRSQDVW

AXIN2

606

Q9Y2T1
QLPEEWENNRESLIV

CPXM2

621

Q8N436
IQLLRRGEVQWVEEE

KIF16B

776

Q96L93
PEIQLDEGWLEDERN

PDZRN4

486

Q6ZMN7
EGERERWLQVLGELQ

CDC42BPG

1051

Q6DT37
LENELNRWRNGETVP

KIF5B

361

P33176
TVPDQEELGEVWQRR

HECW2

726

Q9P2P5
NWELRVELEDFNGNR

FCN3

176

O75636
GLWEENAQLQDAVRR

FAM184B

806

Q9ULE4
LRRNQDNEDEWPLAE

KAT5

16

Q92993
EERDQLLPNLRAVGW

PCBD1

11

P61457
PVRDWILRQRQDDLD

MSLN

566

Q13421
AELWGEQAEARRQIL

GOLGA2

511

Q08379
DLLWLIQDRPDRDND

MCM7

516

P33993
EPETWEQILRRNVLQ

IL4R

546

P24394
PEEELQREWLGNREA

CPN1

316

P15169
LQRPSGEDRWQEKDQ

CCDC150

1051

Q8NCX0
WELEQAGGDARQELR

CROCC2

1136

H7BZ55
EIEQRLALWEGRSNA

FARP1

601

Q9Y4F1
QRWENVEEPNLDELL

CEP250

86

Q9BV73
RLAGQWVEQEVEDRP

ZNHIT6

91

Q9NWK9
ERSLERDQVQLGLDW

CCDC57

416

Q2TAC2
WLKNGERLNPEERIQ

CNTN6

351

Q9UQ52
GDRPLIDWDQIREEG

DDX43

166

Q9NXZ2
PEQLDDWNRIAELQQ

NUMA1

1911

Q14980
LQEEWIPFRRVEEGE

PAFAH2

161

Q99487
WRELQAAPREEQEKL

SYT5

226

O00445
WSEVERLRDEQLNAP

TARS3

26

A2RTX5
RDNRRLGEWDLPEAV

TARS2

686

Q9BW92
WARLEELERQEELLG

URI1

211

O94763
ELNRWRNGEAVPEDE

KIF5C

366

O60282
EPGQARLQDWEDQVR

RECQL4

1126

O94761
IQTDEWRNGPVEERL

MTR

661

Q99707
TQIRELWDRLQIPEE

PRC1

241

O43663
LWDRLQIPEEEREAV

PRC1

246

O43663
RNNLRSIEWDLEDLD

STX6

51

O43752
QGRPRFDWLQDEDEQ

WIZ

131

O95785
QPRQREEILEWEFLT

CHSY1

366

Q86X52
DWEEERQPILQLLTQ

NCAPD2

161

Q15021
ELQEKPEWRLRDVQA

TTPAL

46

Q9BTX7
PLVRDINLQDEDWNE

PRPF8

281

Q6P2Q9
EDLEDSWDRGIPRIN

PRPF8

1406

Q6P2Q9
WREGREFLQDQNPDR

ZNF705A

66

Q6ZN79
IFRLEQGEEPWRLEE

ZNF33B

61

Q06732
INARLREVQTGWEDL

SPTBN2

1036

O15020
WQELQLRERADDPLG

TONSL

51

Q96HA7
PGDINLQDERWQDLN

ARHGAP23

961

Q9P227
PDWKAALQREREEQQ

SOGA1

806

O94964
RQLPAWIEAANQREE

NISCH

616

Q9Y2I1
ELISRLEQRQEPWNV

ZNF682

51

O95780
QAWAREQQRLREGEE

TENM4

2701

Q6N022
EQQRLREGEEGLRAW

TENM4

2706

Q6N022
QEEWRRQLPESLGEG

VPS13B

3736

Q7Z7G8
NTLQRLPQLRWEEAD

TLCD3B

21

Q71RH2
LIAQLERGEAPWREE

ZNF875

81

P10072
LEQIPEIWERLEREN

ZMYND10

331

O75800
RELELAELDQWPQER

PIEZO1

351

Q92508
GPELQRRQLLEEFEW

XPNPEP2

626

O43895
ETALRWLENQDPREV

TIGD5

596

Q53EQ6
WQQRDRHFPEEEQLE

TCHH

1286

Q07283
PEEEGQIIRGWLERE

USP32

371

Q8NFA0
HGQEELNEWLDRREV

ZC3H7B

911

Q9UGR2
ELNPVWNEILEFDLR

MYOF

41

Q9NZM1
DIPWEDLRDNRDLNV

NAA25

646

Q14CX7