Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mannosidase activity	MAN2B2 MANBA MANEAL	1.27e-05	16	58	3	GO:0015923
Domain	Peptidase_M13	MMEL1 ECEL1 MME	9.35e-07	7	57	3	PF01431
Domain	Peptidase_M13_C	MMEL1 ECEL1 MME	9.35e-07	7	57	3	IPR018497
Domain	Peptidase_M13	MMEL1 ECEL1 MME	9.35e-07	7	57	3	IPR000718
Domain	Peptidase_M13_N	MMEL1 ECEL1 MME	9.35e-07	7	57	3	PF05649
Domain	Peptidase_M13_N	MMEL1 ECEL1 MME	9.35e-07	7	57	3	IPR008753
Domain	Oxysterol-bd	OSBPL3 OSBPL7	5.92e-04	12	57	2	IPR000648
Domain	Oxysterol-bd_CS	OSBPL3 OSBPL7	5.92e-04	12	57	2	IPR018494
Domain	Oxysterol_BP	OSBPL3 OSBPL7	5.92e-04	12	57	2	PF01237
Domain	OSBP	OSBPL3 OSBPL7	5.92e-04	12	57	2	PS01013
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH2	8.13e-04	14	57	2	IPR011704
Domain	AAA_5	MDN1 DNAH2	8.13e-04	14	57	2	PF07728
Domain	-	GLIPR1 CLEC18B	9.37e-04	15	57	2	3.40.33.10
Domain	CAP	GLIPR1 CLEC18B	9.37e-04	15	57	2	PF00188
Domain	CAP_domain	GLIPR1 CLEC18B	9.37e-04	15	57	2	IPR014044
Domain	SCP	GLIPR1 CLEC18B	9.37e-04	15	57	2	SM00198
Domain	Allrgn_V5/Tpx1	GLIPR1 CLEC18B	9.37e-04	15	57	2	IPR001283
Domain	MetalloPept_cat_dom	MMEL1 ECEL1 MME	1.94e-03	81	57	3	IPR024079
Domain	-	MMEL1 ECEL1 MME	1.94e-03	81	57	3	3.40.390.10
Domain	ZINC_PROTEASE	MMEL1 ECEL1 MME	3.34e-03	98	57	3	PS00142
Domain	Cyclin_N	CCNF CNTD1	4.55e-03	33	57	2	IPR006671
Domain	Cyclin_N	CCNF CNTD1	4.55e-03	33	57	2	PF00134
Domain	GPS	ADGRL1 ADGRF5	4.82e-03	34	57	2	SM00303
Domain	GPCR_2_secretin-like_CS	ADGRL1 ADGRF5	4.82e-03	34	57	2	IPR017983
Domain	GPS	ADGRL1 ADGRF5	5.10e-03	35	57	2	PF01825
Domain	GPS	ADGRL1 ADGRF5	5.39e-03	36	57	2	PS50221
Domain	GPS	ADGRL1 ADGRF5	5.69e-03	37	57	2	IPR000203
Domain	G_PROTEIN_RECEP_F2_1	ADGRL1 ADGRF5	6.63e-03	40	57	2	PS00649
Domain	-	CCNF CNTD1	6.63e-03	40	57	2	1.10.472.10
Domain	GPCR_2_extracellular_dom	ADGRL1 ADGRF5	6.63e-03	40	57	2	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	ADGRL1 ADGRF5	6.63e-03	40	57	2	PS50227
Domain	Cyclin-like	CCNF CNTD1	7.63e-03	43	57	2	IPR013763
Domain	ARM-like	ARID2 FRYL HECTD1 CFAP69	9.26e-03	270	57	4	IPR011989
Domain	G_PROTEIN_RECEP_F2_2	ADGRL1 ADGRF5	1.02e-02	50	57	2	PS00650
Domain	7tm_2	ADGRL1 ADGRF5	1.02e-02	50	57	2	PF00002
Pubmed	Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences.	MMEL1 MME	2.83e-06	2	59	2	18539150
Pubmed	Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice.	MMEL1 MME	2.83e-06	2	59	2	29191928
Pubmed	In silico based investigation of dynamic variations in neprilysin (NEP and NEP2) proteins for extracting the point of specificity.	MMEL1 MME	2.83e-06	2	59	2	26846903
Pubmed	Nonhemopoietic cell TLR4 signaling is critical in causing early lipopolysaccharide-induced ileus.	CSF1 TLR4	2.83e-06	2	59	2	19846874
Pubmed	Mouse susceptibility to anthrax lethal toxin is influenced by genetic factors in addition to those controlling macrophage sensitivity.	CSF1 TLR4	8.48e-06	3	59	2	15271901
Pubmed	Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7.	OSBPL3 OSBPL7	8.48e-06	3	59	2	14593528
Pubmed	Neprilysin-2 is an important β-amyloid degrading enzyme.	MMEL1 MME	8.48e-06	3	59	2	21224067
Pubmed	Genetic susceptibility to chronic otitis media with effusion: candidate gene single nucleotide polymorphisms.	TLR4 MUC5B	1.69e-05	4	59	2	23929584
Pubmed	Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.	MAN2B2 MANBA	1.69e-05	4	59	2	29773673
Pubmed	A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide.	CSF1 TLR4	4.23e-05	6	59	2	17114485
Pubmed	Fine-tuning nucleophosmin in macrophage differentiation and activation.	CSF1 TLR4	4.23e-05	6	59	2	21876121
Pubmed	The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands.	CSF1 TLR4	7.87e-05	8	59	2	17114491
Pubmed	The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.	OSBPL3 OSBPL7	7.87e-05	8	59	2	17428193
Pubmed	The OSBP-related protein family in humans.	OSBPL3 OSBPL7	1.54e-04	11	59	2	11483621
Pubmed	A family of 12 human genes containing oxysterol-binding domains.	OSBPL3 OSBPL7	1.85e-04	12	59	2	11735225
Pubmed	An oxysterol-binding protein family identified in the mouse.	OSBPL3 OSBPL7	1.85e-04	12	59	2	12215260
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RIMKLB MAN2B2 OSBPL3 ARID2 ADGRF5 HECTD1	1.88e-04	493	59	6	15368895
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	SLC6A12 FADS1	2.54e-04	14	59	2	23378610
Pubmed	Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface.	MAN2B2 MANBA	2.93e-04	15	59	2	8892864
Pubmed	Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity.	OSBPL3 HECTD1	3.79e-04	17	59	2	29299163
Pubmed	Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.	MAN2B2 MANBA	3.79e-04	17	59	2	2355006
Pubmed	Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.	SPTA1 CAPZA2	5.27e-04	20	59	2	18723693
Pubmed	Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.	MAN2B2 MANBA	5.27e-04	20	59	2	12560567
Pubmed	Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.	MAN2B2 MANBA	6.39e-04	22	59	2	8673525
Pubmed	Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.	MAN2B2 MANBA	6.39e-04	22	59	2	9109416
Pubmed	Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.	MAN2B2 MANBA	6.39e-04	22	59	2	11530211
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ADGRL1 ADGRF5 FRYL	6.67e-04	100	59	3	10048485
Pubmed	Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.	MAN2B2 MANBA	7.00e-04	23	59	2	1736542
Pubmed	Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.	MAN2B2 MANBA	7.00e-04	23	59	2	8093218
Pubmed	Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.	MAN2B2 MANBA	7.00e-04	23	59	2	3099781
Pubmed	Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.	MAN2B2 MANBA	7.00e-04	23	59	2	3264072
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CCPG1 RIMKLB PARP14	7.27e-04	103	59	3	10574462
Pubmed	Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.	FADS1 MAN2B2 FGFBP3 ARID2 ADGRF5	8.17e-04	430	59	5	16303743
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	MAN2B2 MANBA	8.28e-04	25	59	2	2283726
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	MAN2B2 MANBA	8.96e-04	26	59	2	8218172
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GLIPR1 CCPG1 MAN2B2 MANBA MANEAL ECEL1 HECTD1 DMXL1	9.18e-04	1201	59	8	35696571
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRL1 ADGRF5	1.12e-03	29	59	2	15203201
Pubmed	Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.	FADS1 TEX14	1.12e-03	29	59	2	38485951
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	CAPZA2 HECTD1	1.44e-03	33	59	2	26296893
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRL1 ADGRF5	1.44e-03	33	59	2	25713288
Cytoband	Ensembl 112 genes in cytogenetic band chr7q31	TSPAN12 TES CAPZA2	7.96e-04	140	59	3	chr7q31
Cytoband	14q12	GPR33 HECTD1	2.31e-03	55	59	2	14q12
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL3 OSBPL7	3.11e-04	12	40	2	670
GeneFamily	C-type lectin domain family	CLEC18B KLRG2	4.84e-03	47	40	2	494
GeneFamily	LIM domain containing	TES FHL5	7.54e-03	59	40	2	1218
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF671 MDN1 ZBED6 OSBPL7 CCDC102B	1.90e-06	154	59	5	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 TES MMEL1 ZNF280B MME	2.58e-06	164	59	5	4ade97931ae1780af7836d988fe117a10b3e88a1
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	SULT1B1 ATP8A1 ADGRF5 FRYL PARP14	4.91e-06	187	59	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ATP8A1 OSBPL3 ARID2 FRYL PARP14	5.44e-06	191	59	5	9454f642c3621370fa23640b631301346b300950
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC6A12 MDN1 ZNF165 SPTA1	3.02e-05	134	59	4	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CSF1 MANEAL MME TEX14	5.19e-05	154	59	4	6c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMEL1 SPTA1 KLRG2 TEX14	5.73e-05	158	59	4	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMEL1 SPTA1 KLRG2 TEX14	5.73e-05	158	59	4	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 MMEL1 GPR33 KLRG2	5.73e-05	158	59	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	Control-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	ADGRF5 ECEL1 CCDC102B FHL5	5.88e-05	159	59	4	6f50c381cd8a26a5a90bf0ce909713cea96910d7
ToppCell	CV-Mild-6\|CV / Virus stimulation, Condition and Cluster	ZNF131 ZNF671 TES FADS1	7.11e-05	167	59	4	cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 MMEL1 ZNF280B MME	7.27e-05	168	59	4	2fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 CSF1 DENND2C ADGRF5	7.61e-05	170	59	4	a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 CSF1 DENND2C ADGRF5	7.61e-05	170	59	4	b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CSF1 ADGRF5 CCDC102B FHL5	7.61e-05	170	59	4	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TES ADGRF5 CCDC102B FHL5	7.79e-05	171	59	4	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 SLC6A12 TLR4 ADGRF5	8.33e-05	174	59	4	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 SLC6A12 TLR4 ADGRF5	8.33e-05	174	59	4	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	ZNF131 ZNF671 TES ADGRL1	8.52e-05	175	59	4	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	Cerebellum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCNF MMEL1 AP5B1	8.83e-05	65	59	3	16e12e133a8bb2ddc459d057975010b2513f81e9
ToppCell	Cerebellum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Gabra6_(Granule_cells)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCNF MMEL1 AP5B1	8.83e-05	65	59	3	8e8dbbc2596e65a9ef7d408548b2ab9a5b27ee0e
ToppCell	Cerebellum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Gabra6_(Granule_cells)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCNF MMEL1 AP5B1	8.83e-05	65	59	3	e0744fcf39b47c1a9e2f7d2743cb08b942929713
ToppCell	Cerebellum-Neuronal-Excitatory-eN1(Slc17a7)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCNF MMEL1 AP5B1	8.83e-05	65	59	3	d2a3354a4c8a998a634c56895722e5896826a681
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FANCB CLEC18B MANEAL ECEL1	8.90e-05	177	59	4	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBCCD1 SULT1B1 TLR4 RNF41	8.90e-05	177	59	4	68f1139fc378f351e3b9e9f392aacb150025bf03
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC6A12 ADGRF5 CCDC102B FHL5	9.91e-05	182	59	4	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	ATP8A1 OSBPL3 ARID2 FRYL	1.08e-04	186	59	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ATP8A1 ZBED6 ARID2 PARP14	1.12e-04	188	59	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RIMKLB KIAA0232 KLRG2 FRYL	1.12e-04	188	59	4	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	TSPAN12 ADGRF5 CCDC102B FHL5	1.15e-04	189	59	4	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN12 ATP8A1 ADGRF5 TEX14	1.22e-04	192	59	4	53d438e35c14e7656585942b788459e6d843c555
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC6A12 ADGRF5 CCDC102B FHL5	1.22e-04	192	59	4	09cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN12 ATP8A1 ADGRF5 TEX14	1.22e-04	192	59	4	9a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	TSPAN12 ADGRF5 CCDC102B FHL5	1.27e-04	194	59	4	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN12 ATP8A1 ADGRF5 TEX14	1.27e-04	194	59	4	8deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN12 ATP8A1 ADGRF5 TEX14	1.27e-04	194	59	4	b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSPAN12 SLC2A10 MMEL1 MUC5B	1.32e-04	196	59	4	020110cd79453df9546fb20802fe38ecadd9fe74
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OSBPL3 MANEAL DENND2C TEX14	1.34e-04	197	59	4	749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TSPAN12 ADGRF5 ECEL1 CCDC102B	1.37e-04	198	59	4	5e274c5597d8720290d452465f0bd40637cb3f27
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRF5 ECEL1 CCDC102B FHL5	1.37e-04	198	59	4	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	Non-neuronal-Postmitotic\|World / Primary Cells by Cluster	GLIPR1 CSF1 TLR4 ADGRF5	1.40e-04	199	59	4	f6a9119ad32d9f0173c432de353b5315a7cf01ad
ToppCell	tumor_Lung-Endothelial_cells-Tip-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	TSPAN12 CSF1 ADGRF5 PARP14	1.40e-04	199	59	4	80c8641cfd84436eadf2234f1313749e2f73331f
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRF5 ECEL1 CCDC102B FHL5	1.40e-04	199	59	4	9e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCell	COVID-19-COVID-19_Mild-Myeloid-Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	SULT1B1 CSF1 TLR4 MME	1.40e-04	199	59	4	9f6b6731186ef399f952a75879eba66fd8ed3494
ToppCell	Tracheal-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRF5 ECEL1 CCDC102B FHL5	1.40e-04	199	59	4	cefc3b50f65e95da850e4720c7b44bf584073491
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	GLIPR1 TLR4 DNAH2 CCDC102B	1.42e-04	200	59	4	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	GLIPR1 TLR4 DNAH2 CCDC102B	1.42e-04	200	59	4	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRF5 ECEL1 CCDC102B FHL5	1.42e-04	200	59	4	fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Fos_(Deep_layer_pyramidal_cells--layer_5_(IEG))\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FANCB AP5B1 DNAH2	1.46e-04	77	59	3	4879a1a72b950dadb78bc0312be75f1a32b935d5
Drug	RB 38A	TES MMEL1 MME	5.74e-07	7	59	3	CID000129130
Drug	AC1Q5WMQ	MMEL1 MME	6.60e-06	2	59	2	CID000134383
Drug	candoxatrilat	MMEL1 MME	1.98e-05	3	59	2	ctd:C060942
Drug	boroleucine	MMEL1 MME	1.98e-05	3	59	2	CID000127495
Disease	otitis media (is_marker_for)	TLR4 MUC5B	1.63e-04	10	57	2	DOID:10754 (is_marker_for)
Disease	sclerosing cholangitis	MMEL1 MANBA MME	2.87e-04	66	57	3	EFO_0004268
Disease	Diabetic Asymmetric Polyneuropathy	TLR4 MME	3.29e-04	14	57	2	C0393835
Disease	Diabetic Neuralgia	TLR4 MME	3.29e-04	14	57	2	C0751074
Disease	Diabetic Neuropathies	TLR4 MME	3.29e-04	14	57	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	TLR4 MME	3.29e-04	14	57	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	TLR4 MME	3.29e-04	14	57	2	C0271673
Disease	Diabetic Mononeuropathy	TLR4 MME	3.29e-04	14	57	2	C0271678
Disease	Diabetic Autonomic Neuropathy	TLR4 MME	3.29e-04	14	57	2	C0271686
Disease	Diabetic Amyotrophy	TLR4 MME	3.29e-04	14	57	2	C0271685
Disease	Diabetic Polyneuropathies	TLR4 MME	3.29e-04	14	57	2	C0271680
Disease	heel bone mineral density, urate measurement	OSBPL3 SPTA1 CAPZA2 MINDY4	4.29e-04	182	57	4	EFO_0004531, EFO_0009270
Disease	susceptibility to scarlet fever measurement	MANBA FRYL MME	4.87e-04	79	57	3	EFO_0008409
Disease	Renal Insufficiency	TLR4 MME	4.89e-04	17	57	2	C1565489
Disease	sinusitis (is_marker_for)	TLR4 MUC5B	5.50e-04	18	57	2	DOID:0050127 (is_marker_for)
Disease	mean platelet volume	RIMKLB FADS1 KIAA0232 SPTA1 DENND2C CAPZA2 ADGRF5 FRYL	7.30e-04	1020	57	8	EFO_0004584
Disease	Uterine leiomyoma	TSPAN12 SULT1B1 DNAH2	7.36e-04	91	57	3	HP_0000131
Disease	Lung Injury	TLR4 MME	7.52e-04	21	57	2	C0273115
Disease	Chronic Lung Injury	TLR4 MME	7.52e-04	21	57	2	C2350344
Disease	Kidney Failure	TLR4 MME	8.26e-04	22	57	2	C0035078
Disease	insulin sensitivity measurement	SLC6A12 CSF1	9.04e-04	23	57	2	EFO_0004471
Disease	phosphatidylserines measurement	FADS1 CFAP69	9.04e-04	23	57	2	EFO_0020049
Disease	heart conduction disease (implicated_via_orthology)	MMEL1 MME	1.75e-03	32	57	2	DOID:10273 (implicated_via_orthology)
Disease	refractive error, self reported educational attainment	ARID2 ECEL1	1.98e-03	34	57	2	EFO_0004784, MONDO_0004892
Disease	platelet component distribution width	FADS1 KIAA0232 SPTA1 DENND2C CAPZA2 ADGRF5	3.30e-03	755	57	6	EFO_0007984
Disease	end stage renal disease (is_marker_for)	CSF1 TLR4	3.59e-03	46	57	2	DOID:783 (is_marker_for)
Disease	hemolysis	SPTA1 MINDY4	3.75e-03	47	57	2	EFO_0009473

Protein segments in the cluster

Peptide	Gene	Start	Entry
FEKQRNDSWENHTTC	ZNF280B	331	Q86YH2
HLEDKNHFNANCSFW	ADGRL1	791	O94910
DNHWNFGTALCKVFN	GPR33	91	Q49SQ1
EKFACQWLNAHFEVN	ARID2	521	Q68CP9
YLTWQCHNKTANDFV	DMXL1	2831	Q9Y485
QNALDFNTKVFWVHC	ATP8A1	931	Q9Y2Q0
AFANTWKAQAACANA	MUC5B	586	Q9HC84
WKAQAACANARNSFE	MUC5B	591	Q9HC84
CAEKWHSLCNFFVNF	FGFBP3	241	Q8TAT2
QQSCETLFHSWKDFE	MDN1	4406	Q9NU22
QIAKAWASNCQFSHN	GLIPR1	66	P48060
RAFAFCNSFNWAANL	SLC2A10	446	O95528
WTKNSAFEENEHCSN	KIAA0232	691	Q92628
KQFFLNNWHIFLQNC	FRYL	326	O94915
NHKQLFFLNFAQVWC	MME	681	P08473
TLNFLQAAAAHCTNW	AP5B1	556	Q2VPB7
WSNFSTQHFREQSEC	MMEL1	636	Q495T6
THDQLFFIAFAQNWC	ECEL1	706	O95672
NNACAVWKESFQVAA	FANCB	306	Q8NB91
EWQYNDNNTSHCFNK	PARP14	1536	Q460N5
FCHWNELDQFINKFF	CCPG1	671	Q9ULG6
KFICFQDSQWHSECF	FHL5	236	Q5TD97
NCHSNDDKNAWFAID	HECTD1	1126	Q9ULT8
AQAWEASQAFCSAYH	KLRG2	311	A4D1S0
DKDWNIFSKNCNNSF	CSF1	161	P09603
KVFSQCVTHCSFSQW	GNRHR	191	P30968
VDNHASVWACASFQE	CCNF	66	P41002
HFFKNESESNWVCSR	DENND2C	106	Q68D51
QATCNVHKSAFNDWF	FADS1	361	O60427
CHVNFVRKEQCSFSW	MANBA	176	O00462
AQFIFAKNCSQVWAE	FAM166B	101	A8MTA8
SHQNWKAVKNFCDAN	MANEAL	336	Q5VSG8
WGCDKQFFNASVQFA	MAN2B2	286	Q9Y2E5
FCDNPKTAAHVNAWQ	CFAP69	636	A5D8W1
KFSLVQHCNEWQNKF	DNAH2	1021	Q9P225
HAFCNACITQWFSQQ	RNF41	36	Q9H4P4
NFCAHSYNTNKWDIC	CCDC102B	56	Q68D86
AASAFIQNHECWSQV	CNTD1	261	Q8N815
SACHAESRNFVFWQD	OSBPL3	636	Q9H4L5
ISACHAESENFAFWQ	OSBPL7	586	Q9BZF2
FNAADKVNFATWNQA	GTF2F1	31	P35269
AENQNWHLKHFCCFD	TES	316	Q9UGI8
QVKTEFASCWNSQEF	TEX14	1236	Q8IWB6
TCNNFWNTEHCTDFL	SLC6A12	156	P48065
TCAFASNWEKIEQFH	SULT1B1	21	O43704
CYKHNFNASSVSWCS	ADGRF5	621	Q8IZF2
ACIESHQFQAKNFWN	CAPZA2	156	P47755
QASAAFNWNDQRCKT	CLEC18B	421	Q6UXF7
ACGKQFWFSTDFDQH	ZNF671	196	Q8TAW3
CFNEEWKLQSFSFSN	MINDY4	426	Q4G0A6
KLAQFNNWFTWCHNC	MIOS	816	Q9NXC5
NCVNKFWTFQELAGH	RIMKLB	111	Q9ULI2
VEFAHKASALNNWCE	SPTA1	2046	P02549
LTHAWNFFQREFKCC	TSPAN12	146	O95859
CSWQSECIFTKNSHF	ZBED6	911	P86452
TCDQSFKWNSDFINH	ZNF165	296	P49910
VCNSVFNSWDQFKDH	ZNF131	396	P52739
CHNKNWNDYSHQAFV	TBCCD1	161	Q9NVR7
LTEHCNEVWFCKFSN	WDR26	351	Q9H7D7
FACTCEHQSFLQWIK	TLR4	581	O00206
CDECHKAFNWFATLT	ZNF680	296	Q8NEM1