| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | protein serine kinase activity | 9.66e-06 | 363 | 42 | 7 | GO:0106310 | |
| GeneOntologyMolecularFunction | protein serine/threonine kinase activity | 3.63e-05 | 446 | 42 | 7 | GO:0004674 | |
| GeneOntologyMolecularFunction | protein kinase activity | 2.31e-04 | 600 | 42 | 7 | GO:0004672 | |
| GeneOntologyMolecularFunction | protein kinase C binding | 3.61e-04 | 66 | 42 | 3 | GO:0005080 | |
| GeneOntologyMolecularFunction | phosphotransferase activity, alcohol group as acceptor | 6.31e-04 | 709 | 42 | 7 | GO:0016773 | |
| GeneOntologyMolecularFunction | transferase activity, transferring phosphorus-containing groups | 6.54e-04 | 938 | 42 | 8 | GO:0016772 | |
| GeneOntologyMolecularFunction | kinase activity | 9.79e-04 | 764 | 42 | 7 | GO:0016301 | |
| GeneOntologyBiologicalProcess | fatty acid transmembrane transport | 1.18e-05 | 22 | 42 | 3 | GO:1902001 | |
| GeneOntologyBiologicalProcess | regulation of fatty acid beta-oxidation | 1.54e-05 | 24 | 42 | 3 | GO:0031998 | |
| GeneOntologyBiologicalProcess | negative regulation of long-chain fatty acid import across plasma membrane | 2.42e-05 | 4 | 42 | 2 | GO:0010748 | |
| GeneOntologyBiologicalProcess | regulation of atrial cardiac muscle cell action potential | 2.42e-05 | 4 | 42 | 2 | GO:0098910 | |
| GeneOntologyBiologicalProcess | negative regulation of long-chain fatty acid import into cell | 2.42e-05 | 4 | 42 | 2 | GO:0140213 | |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | SRF CARM1 CAVIN4 AKT1 EVX1 AKT2 PRDM15 HSPA5 ZNF175 TP53BP1 NFKBIA | 7.66e-05 | 1390 | 42 | 11 | GO:0045944 |
| GeneOntologyBiologicalProcess | regulation of long-chain fatty acid import across plasma membrane | 8.45e-05 | 7 | 42 | 2 | GO:0010746 | |
| GeneOntologyBiologicalProcess | positive regulation of sodium ion transport | 8.53e-05 | 42 | 42 | 3 | GO:0010765 | |
| GeneOntologyBiologicalProcess | regulation of fatty acid oxidation | 1.12e-04 | 46 | 42 | 3 | GO:0046320 | |
| GeneOntologyBiologicalProcess | peripheral nervous system myelin maintenance | 1.44e-04 | 9 | 42 | 2 | GO:0032287 | |
| GeneOntologyBiologicalProcess | regulation of long-chain fatty acid import into cell | 1.44e-04 | 9 | 42 | 2 | GO:0140212 | |
| GeneOntologyBiologicalProcess | replication fork processing | 1.62e-04 | 52 | 42 | 3 | GO:0031297 | |
| GeneOntologyBiologicalProcess | negative regulation of fatty acid transport | 2.20e-04 | 11 | 42 | 2 | GO:2000192 | |
| GeneOntologyBiologicalProcess | DNA-templated DNA replication maintenance of fidelity | 2.48e-04 | 60 | 42 | 3 | GO:0045005 | |
| GeneOntologyBiologicalProcess | long-chain fatty acid import across plasma membrane | 2.64e-04 | 12 | 42 | 2 | GO:0015911 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell signaling | 2.64e-04 | 12 | 42 | 2 | GO:0086027 | |
| GeneOntologyBiologicalProcess | AV node cell action potential | 2.64e-04 | 12 | 42 | 2 | GO:0086016 | |
| GeneOntologyBiologicalProcess | positive regulation of transport | 2.68e-04 | 1081 | 42 | 9 | GO:0051050 | |
| GeneOntologyBiologicalProcess | protein localization to organelle | 2.87e-04 | 1091 | 42 | 9 | GO:0033365 | |
| GeneOntologyBiologicalProcess | positive regulation of fatty acid beta-oxidation | 3.11e-04 | 13 | 42 | 2 | GO:0032000 | |
| GeneOntologyBiologicalProcess | peptidyl-serine phosphorylation | 3.83e-04 | 307 | 42 | 5 | GO:0018105 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell communication | 4.18e-04 | 15 | 42 | 2 | GO:0086067 | |
| GeneOntologyBiologicalProcess | peptidyl-serine modification | 4.56e-04 | 319 | 42 | 5 | GO:0018209 | |
| GeneOntologyBiologicalProcess | long-chain fatty acid transport | 4.60e-04 | 74 | 42 | 3 | GO:0015909 | |
| GeneOntologyBiologicalProcess | response to UV-C | 4.77e-04 | 16 | 42 | 2 | GO:0010225 | |
| GeneOntologyBiologicalProcess | cellular response to ionizing radiation | 4.98e-04 | 76 | 42 | 3 | GO:0071479 | |
| GeneOntologyBiologicalProcess | negative regulation of lipid localization | 5.37e-04 | 78 | 42 | 3 | GO:1905953 | |
| GeneOntologyBiologicalProcess | regulation of lipid catabolic process | 5.37e-04 | 78 | 42 | 3 | GO:0050994 | |
| GeneOntologyBiologicalProcess | positive regulation of fat cell differentiation | 5.57e-04 | 79 | 42 | 3 | GO:0045600 | |
| GeneOntologyBiologicalProcess | plasma membrane organization | 5.71e-04 | 188 | 42 | 4 | GO:0007009 | |
| GeneOntologyBiologicalProcess | fatty acid beta-oxidation | 5.78e-04 | 80 | 42 | 3 | GO:0006635 | |
| GeneOntologyBiologicalProcess | positive regulation of glycogen biosynthetic process | 6.07e-04 | 18 | 42 | 2 | GO:0045725 | |
| GeneOntologyBiologicalProcess | myelin maintenance | 6.07e-04 | 18 | 42 | 2 | GO:0043217 | |
| GeneOntologyBiologicalProcess | cellular response to radiation | 6.42e-04 | 194 | 42 | 4 | GO:0071478 | |
| GeneOntologyBiologicalProcess | mammary gland epithelium development | 6.67e-04 | 84 | 42 | 3 | GO:0061180 | |
| GeneOntologyBiologicalProcess | mammary gland epithelial cell differentiation | 6.77e-04 | 19 | 42 | 2 | GO:0060644 | |
| GeneOntologyBiologicalProcess | atrial cardiac muscle cell to AV node cell communication | 6.77e-04 | 19 | 42 | 2 | GO:0086066 | |
| GeneOntologyBiologicalProcess | atrial cardiac muscle cell to AV node cell signaling | 6.77e-04 | 19 | 42 | 2 | GO:0086026 | |
| GeneOntologyBiologicalProcess | atrial cardiac muscle cell action potential | 6.77e-04 | 19 | 42 | 2 | GO:0086014 | |
| GeneOntologyBiologicalProcess | peptidyl-amino acid modification | 6.87e-04 | 976 | 42 | 8 | GO:0018193 | |
| GeneOntologyBiologicalProcess | long-chain fatty acid import into cell | 7.51e-04 | 20 | 42 | 2 | GO:0044539 | |
| GeneOntologyBiologicalProcess | intrinsic apoptotic signaling pathway | 7.98e-04 | 361 | 42 | 5 | GO:0097193 | |
| GeneOntologyBiologicalProcess | protein localization to endoplasmic reticulum | 8.15e-04 | 90 | 42 | 3 | GO:0070972 | |
| GeneOntologyBiologicalProcess | cardiac myofibril assembly | 8.29e-04 | 21 | 42 | 2 | GO:0055003 | |
| GeneOntologyBiologicalProcess | response to nitrogen compound | 8.78e-04 | 1272 | 42 | 9 | GO:1901698 | |
| GeneOntologyBiologicalProcess | cellular response to abiotic stimulus | 9.02e-04 | 371 | 42 | 5 | GO:0071214 | |
| GeneOntologyBiologicalProcess | cellular response to environmental stimulus | 9.02e-04 | 371 | 42 | 5 | GO:0104004 | |
| GeneOntologyBiologicalProcess | positive regulation of fatty acid oxidation | 9.11e-04 | 22 | 42 | 2 | GO:0046321 | |
| GeneOntologyBiologicalProcess | membrane depolarization during cardiac muscle cell action potential | 9.97e-04 | 23 | 42 | 2 | GO:0086012 | |
| GeneOntologyBiologicalProcess | cell migration involved in sprouting angiogenesis | 1.07e-03 | 99 | 42 | 3 | GO:0002042 | |
| GeneOntologyBiologicalProcess | positive regulation of glycogen metabolic process | 1.09e-03 | 24 | 42 | 2 | GO:0070875 | |
| GeneOntologyBiologicalProcess | regulation of sodium ion transport | 1.14e-03 | 101 | 42 | 3 | GO:0002028 | |
| GeneOntologyBiologicalProcess | lipid import into cell | 1.18e-03 | 25 | 42 | 2 | GO:0140354 | |
| GeneOntologyBiologicalProcess | atrial septum development | 1.18e-03 | 25 | 42 | 2 | GO:0003283 | |
| GeneOntologyBiologicalProcess | maintenance of location | 1.21e-03 | 396 | 42 | 5 | GO:0051235 | |
| GeneOntologyBiologicalProcess | cellular response to organic cyclic compound | 1.33e-03 | 605 | 42 | 6 | GO:0071407 | |
| GeneOntologyBiologicalProcess | maintenance of protein location | 1.53e-03 | 112 | 42 | 3 | GO:0045185 | |
| GeneOntologyBiologicalProcess | regulation of cardiac conduction | 1.59e-03 | 29 | 42 | 2 | GO:1903779 | |
| GeneOntologyBiologicalProcess | fatty acid catabolic process | 1.70e-03 | 116 | 42 | 3 | GO:0009062 | |
| GeneOntologyBiologicalProcess | eosinophil chemotaxis | 1.70e-03 | 30 | 42 | 2 | GO:0048245 | |
| GeneOntologyBiologicalProcess | regulation of cardiac muscle cell action potential | 1.70e-03 | 30 | 42 | 2 | GO:0098901 | |
| GeneOntologyBiologicalProcess | response to X-ray | 1.70e-03 | 30 | 42 | 2 | GO:0010165 | |
| GeneOntologyBiologicalProcess | positive regulation of DNA-binding transcription factor activity | 1.92e-03 | 261 | 42 | 4 | GO:0051091 | |
| GeneOntologyBiologicalProcess | negative regulation of organic acid transport | 1.93e-03 | 32 | 42 | 2 | GO:0032891 | |
| GeneOntologyBiologicalProcess | fatty acid oxidation | 1.96e-03 | 122 | 42 | 3 | GO:0019395 | |
| GeneOntologyBiologicalProcess | positive regulation of lipid catabolic process | 2.05e-03 | 33 | 42 | 2 | GO:0050996 | |
| GeneOntologyBiologicalProcess | peripheral nervous system axon ensheathment | 2.05e-03 | 33 | 42 | 2 | GO:0032292 | |
| GeneOntologyBiologicalProcess | myelination in peripheral nervous system | 2.05e-03 | 33 | 42 | 2 | GO:0022011 | |
| GeneOntologyBiologicalProcess | positive regulation of monoatomic ion transport | 2.06e-03 | 266 | 42 | 4 | GO:0043270 | |
| GeneOntologyBiologicalProcess | regulation of DNA-binding transcription factor activity | 2.09e-03 | 449 | 42 | 5 | GO:0051090 | |
| GeneOntologyBiologicalProcess | positive regulation of endothelial cell proliferation | 2.10e-03 | 125 | 42 | 3 | GO:0001938 | |
| GeneOntologyBiologicalProcess | eosinophil migration | 2.18e-03 | 34 | 42 | 2 | GO:0072677 | |
| GeneOntologyBiologicalProcess | cell-cell signaling involved in cardiac conduction | 2.18e-03 | 34 | 42 | 2 | GO:0086019 | |
| MousePheno | abnormal corpus callosum morphology | 1.19e-05 | 129 | 33 | 5 | MP:0000780 | |
| MousePheno | abnormal dorsal telencephalic commissure morphology | 1.34e-05 | 132 | 33 | 5 | MP:0008219 | |
| MousePheno | abnormal brain commissure morphology | 3.48e-05 | 161 | 33 | 5 | MP:0002199 | |
| MousePheno | abnormal nervous system tract morphology | 7.48e-05 | 189 | 33 | 5 | MP:0000778 | |
| MousePheno | abnormal brain white matter morphology | 1.12e-04 | 206 | 33 | 5 | MP:0008026 | |
| MousePheno | decreased fetal size | 1.84e-04 | 229 | 33 | 5 | MP:0004200 | |
| MousePheno | abnormal fetal size | 2.16e-04 | 237 | 33 | 5 | MP:0004198 | |
| MousePheno | increased mortality induced by ionizing radiation | 2.31e-04 | 51 | 33 | 3 | MP:0003992 | |
| MousePheno | abnormal corpus callosum size | 2.45e-04 | 52 | 33 | 3 | MP:0020573 | |
| MousePheno | increased T cell derived lymphoma incidence | 2.59e-04 | 53 | 33 | 3 | MP:0002024 | |
| MousePheno | increased thymus tumor incidence | 2.74e-04 | 54 | 33 | 3 | MP:0010365 | |
| MousePheno | abnormal mortality induced by ionizing radiation | 2.89e-04 | 55 | 33 | 3 | MP:0020149 | |
| MousePheno | abnormal response to radiation | 3.22e-04 | 57 | 33 | 3 | MP:0012734 | |
| MousePheno | decreased hepatocyte number | 5.57e-04 | 15 | 33 | 2 | MP:0000606 | |
| MousePheno | increased lymphoma incidence | 5.73e-04 | 164 | 33 | 4 | MP:0012431 | |
| MousePheno | abnormal double-strand DNA break repair | 5.89e-04 | 70 | 33 | 3 | MP:0010948 | |
| MousePheno | decreased embryo size | 7.32e-04 | 659 | 33 | 7 | MP:0001698 | |
| MousePheno | abnormal fetal growth/weight/body size | 7.62e-04 | 312 | 33 | 5 | MP:0004197 | |
| Domain | Pkinase_C | 3.17e-08 | 42 | 41 | 5 | PF00433 | |
| Domain | AGC-kinase_C | 1.39e-07 | 56 | 41 | 5 | IPR000961 | |
| Domain | AGC_KINASE_CTER | 1.39e-07 | 56 | 41 | 5 | PS51285 | |
| Domain | S_TK_X | 1.39e-07 | 56 | 41 | 5 | SM00133 | |
| Domain | Ser/Thr_kinase_AS | 1.13e-05 | 357 | 41 | 7 | IPR008271 | |
| Domain | S_TKc | 1.17e-05 | 359 | 41 | 7 | SM00220 | |
| Domain | PROTEIN_KINASE_ST | 1.24e-05 | 362 | 41 | 7 | PS00108 | |
| Domain | Pkinase | 1.72e-05 | 381 | 41 | 7 | PF00069 | |
| Domain | DUF1908 | 2.81e-05 | 4 | 41 | 2 | PF08926 | |
| Domain | MA_Ser/Thr_Kinase_dom | 2.81e-05 | 4 | 41 | 2 | IPR015022 | |
| Domain | MAST_pre-PK_dom | 2.81e-05 | 4 | 41 | 2 | IPR023142 | |
| Domain | - | 2.81e-05 | 4 | 41 | 2 | 1.20.1480.20 | |
| Domain | PROTEIN_KINASE_ATP | 5.64e-05 | 459 | 41 | 7 | PS00107 | |
| Domain | Pkinase_C | 7.24e-05 | 37 | 41 | 3 | IPR017892 | |
| Domain | Prot_kinase_dom | 8.40e-05 | 489 | 41 | 7 | IPR000719 | |
| Domain | PROTEIN_KINASE_DOM | 8.84e-05 | 493 | 41 | 7 | PS50011 | |
| Domain | Kinase-like_dom | 1.59e-04 | 542 | 41 | 7 | IPR011009 | |
| Domain | Protein_kinase_ATP_BS | 1.38e-03 | 379 | 41 | 5 | IPR017441 | |
| Domain | Ankyrin_rpt | 2.55e-03 | 262 | 41 | 4 | IPR002110 | |
| Domain | PDZ | 4.41e-03 | 151 | 41 | 3 | PS50106 | |
| Domain | PDZ | 4.49e-03 | 152 | 41 | 3 | IPR001478 | |
| Pathway | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | 1.07e-08 | 12 | 32 | 4 | MM14777 | |
| Pathway | KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY | 2.15e-08 | 14 | 32 | 4 | M47467 | |
| Pathway | KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY | 2.15e-08 | 14 | 32 | 4 | M47536 | |
| Pathway | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | 2.15e-08 | 14 | 32 | 4 | M3862 | |
| Pathway | KEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY | 1.06e-07 | 5 | 32 | 3 | M48999 | |
| Pathway | KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY | 2.12e-07 | 6 | 32 | 3 | M47523 | |
| Pathway | REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING | 2.25e-07 | 24 | 32 | 4 | M27952 | |
| Pathway | REACTOME_CONSTITUTIVE_SIGNALING_BY_AKT1_E17K_IN_CANCER | 3.16e-07 | 26 | 32 | 4 | M27558 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY | 3.70e-07 | 7 | 32 | 3 | M47407 | |
| Pathway | KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY | 3.70e-07 | 7 | 32 | 3 | M47790 | |
| Pathway | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 3.80e-07 | 67 | 32 | 5 | M10462 | |
| Pathway | KEGG_CHRONIC_MYELOID_LEUKEMIA | 5.85e-07 | 73 | 32 | 5 | M321 | |
| Pathway | KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47399 | |
| Pathway | KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47394 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47395 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47404 | |
| Pathway | KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47405 | |
| Pathway | KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47803 | |
| Pathway | REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION | 5.90e-07 | 8 | 32 | 3 | M27806 | |
| Pathway | KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47482 | |
| Pathway | KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47498 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY | 5.90e-07 | 8 | 32 | 3 | M47715 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 6.59e-07 | 31 | 32 | 4 | M47540 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY | 6.59e-07 | 31 | 32 | 4 | M47541 | |
| Pathway | WP_RESISTIN_AS_A_REGULATOR_OF_INFLAMMATION | 8.54e-07 | 33 | 32 | 4 | M39745 | |
| Pathway | KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47397 | |
| Pathway | KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47392 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47391 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47402 | |
| Pathway | KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47802 | |
| Pathway | KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47490 | |
| Pathway | KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47481 | |
| Pathway | REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING | 8.84e-07 | 9 | 32 | 3 | MM15666 | |
| Pathway | KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 8.84e-07 | 9 | 32 | 3 | M47972 | |
| Pathway | WP_GLIOBLASTOMA_SIGNALING | 1.11e-06 | 83 | 32 | 5 | M39637 | |
| Pathway | REACTOME_REGULATION_OF_TP53_DEGRADATION | 1.22e-06 | 36 | 32 | 4 | MM15339 | |
| Pathway | KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 1.26e-06 | 10 | 32 | 3 | M47400 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY | 1.26e-06 | 10 | 32 | 3 | M47401 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY | 1.26e-06 | 10 | 32 | 3 | M47615 | |
| Pathway | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS | 1.26e-06 | 10 | 32 | 3 | M27095 | |
| Pathway | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS | 1.26e-06 | 10 | 32 | 3 | MM14778 | |
| Pathway | REACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION | 1.37e-06 | 37 | 32 | 4 | M27641 | |
| Pathway | KEGG_PROSTATE_CANCER | 1.58e-06 | 89 | 32 | 5 | M13191 | |
| Pathway | KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47797 | |
| Pathway | KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47403 | |
| Pathway | KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47406 | |
| Pathway | KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47484 | |
| Pathway | KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47499 | |
| Pathway | KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47756 | |
| Pathway | KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339 | 1.73e-06 | 11 | 32 | 3 | M47791 | |
| Pathway | KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY | 1.73e-06 | 11 | 32 | 3 | M47501 | |
| Pathway | KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY | 2.31e-06 | 12 | 32 | 3 | M47393 | |
| Pathway | KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350 | 2.31e-06 | 12 | 32 | 3 | M47798 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 2.31e-06 | 12 | 32 | 3 | M47558 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY | 2.31e-06 | 12 | 32 | 3 | M47559 | |
| Pathway | REACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS | 2.31e-06 | 12 | 32 | 3 | M45022 | |
| Pathway | REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS | 2.31e-06 | 12 | 32 | 3 | MM15657 | |
| Pathway | REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS | 2.31e-06 | 12 | 32 | 3 | M27939 | |
| Pathway | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | 2.31e-06 | 12 | 32 | 3 | MM14550 | |
| Pathway | KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY | 2.99e-06 | 13 | 32 | 3 | M47398 | |
| Pathway | KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY | 2.99e-06 | 13 | 32 | 3 | M47603 | |
| Pathway | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | 2.99e-06 | 13 | 32 | 3 | M549 | |
| Pathway | KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY | 3.80e-06 | 14 | 32 | 3 | M47390 | |
| Pathway | REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS | 3.80e-06 | 14 | 32 | 3 | MM15341 | |
| Pathway | REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS | 3.80e-06 | 14 | 32 | 3 | M27638 | |
| Pathway | KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY | 4.75e-06 | 15 | 32 | 3 | M47389 | |
| Pathway | KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY | 4.75e-06 | 15 | 32 | 3 | M47663 | |
| Pathway | REACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA | 4.75e-06 | 15 | 32 | 3 | M26902 | |
| Pathway | KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY | 4.75e-06 | 15 | 32 | 3 | M47475 | |
| Pathway | WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS | 4.75e-06 | 15 | 32 | 3 | M48306 | |
| Pathway | KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 4.75e-06 | 15 | 32 | 3 | M47971 | |
| Pathway | KEGG_PATHWAYS_IN_CANCER | 6.65e-06 | 325 | 32 | 7 | M12868 | |
| Pathway | WP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM | 6.88e-06 | 55 | 32 | 4 | M39598 | |
| Pathway | WP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES | 7.07e-06 | 17 | 32 | 3 | M48086 | |
| Pathway | SA_PTEN_PATHWAY | 7.07e-06 | 17 | 32 | 3 | M12771 | |
| Pathway | SA_TRKA_RECEPTOR | 7.07e-06 | 17 | 32 | 3 | M18895 | |
| Pathway | WP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION | 1.00e-05 | 19 | 32 | 3 | M39370 | |
| Pathway | KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY | 1.00e-05 | 19 | 32 | 3 | M47525 | |
| Pathway | WP_CANCER_PATHWAYS | 1.30e-05 | 507 | 32 | 8 | M48302 | |
| Pathway | KEGG_GLIOMA | 1.34e-05 | 65 | 32 | 4 | M1835 | |
| Pathway | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | 1.37e-05 | 21 | 32 | 3 | M14966 | |
| Pathway | REACTOME_CTLA4_INHIBITORY_SIGNALING | 1.37e-05 | 21 | 32 | 3 | M5876 | |
| Pathway | REACTOME_CTLA4_INHIBITORY_SIGNALING | 1.37e-05 | 21 | 32 | 3 | MM14996 | |
| Pathway | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | 1.59e-05 | 22 | 32 | 3 | M13897 | |
| Pathway | REACTOME_FOXO_MEDIATED_TRANSCRIPTION | 1.59e-05 | 22 | 32 | 3 | MM15656 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY | 1.59e-05 | 22 | 32 | 3 | M47919 | |
| Pathway | WP_MELANOMA | 1.61e-05 | 68 | 32 | 4 | M39811 | |
| Pathway | REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY | 1.80e-05 | 70 | 32 | 4 | MM15389 | |
| Pathway | KEGG_PANCREATIC_CANCER | 1.80e-05 | 70 | 32 | 4 | M9726 | |
| Pathway | WP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR | 1.82e-05 | 23 | 32 | 3 | MM15952 | |
| Pathway | WP_SILDENAFIL_TREATMENT | 1.82e-05 | 23 | 32 | 3 | M46455 | |
| Pathway | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | 1.82e-05 | 23 | 32 | 3 | MM14993 | |
| Pathway | KEGG_MELANOMA | 1.91e-05 | 71 | 32 | 4 | M15798 | |
| Pathway | KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY | 2.08e-05 | 24 | 32 | 3 | M47460 | |
| Pathway | WP_REGULATION_OF_APOPTOSIS_BY_PARATHYROID_HORMONERELATED_PROTEIN | 2.36e-05 | 25 | 32 | 3 | M39533 | |
| Pathway | WP_RELATIONSHIP_BETWEEN_INFLAMMATION_COX2_AND_EGFR | 2.36e-05 | 25 | 32 | 3 | M39794 | |
| Pathway | WP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION | 2.36e-05 | 25 | 32 | 3 | M39384 | |
| Pathway | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | 2.36e-05 | 25 | 32 | 3 | M14301 | |
| Pathway | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 2.37e-05 | 75 | 32 | 4 | M5436 | |
| Pathway | REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | 2.37e-05 | 75 | 32 | 4 | M27874 | |
| Pubmed | Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival. | 2.75e-11 | 6 | 42 | 4 | 10869418 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 17912369 | ||
| Pubmed | Differential activation of AKT isoforms by growth factors in human myotubes. | 1.64e-09 | 3 | 42 | 3 | 37879895 | |
| Pubmed | Differential prognostic values of the three AKT isoforms in acute myeloid leukemia. | 1.64e-09 | 3 | 42 | 3 | 38528080 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 15987444 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 19825827 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 16540465 | ||
| Pubmed | Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH. | 1.64e-09 | 3 | 42 | 3 | 20102399 | |
| Pubmed | Distinct roles of the three Akt isoforms in lactogenic differentiation and involution. | 1.64e-09 | 3 | 42 | 3 | 18561256 | |
| Pubmed | Differential effects of Akt isoforms on somatic cell reprogramming. | 1.64e-09 | 3 | 42 | 3 | 25037569 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 38396845 | ||
| Pubmed | AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity. | 1.64e-09 | 3 | 42 | 3 | 29173281 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 21590431 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 29235817 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 34296180 | ||
| Pubmed | Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt. | 1.64e-09 | 3 | 42 | 3 | 17982014 | |
| Pubmed | Opposing functions of Akt isoforms in lung tumor initiation and progression. | 1.64e-09 | 3 | 42 | 3 | 24722238 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 24039187 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 16923958 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 17202487 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 26953242 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 23929892 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 19805051 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 25233414 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 21555366 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 32796067 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 25811375 | ||
| Pubmed | Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development. | 1.64e-09 | 3 | 42 | 3 | 20724596 | |
| Pubmed | Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS. | 1.64e-09 | 3 | 42 | 3 | 27098694 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 28931550 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 10579998 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 20398329 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 33325370 | ||
| Pubmed | The Akt isoforms are present at distinct subcellular locations. | 1.64e-09 | 3 | 42 | 3 | 20018949 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 24247267 | ||
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 17895832 | ||
| Pubmed | Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3. | 1.64e-09 | 3 | 42 | 3 | 10491192 | |
| Pubmed | 1.64e-09 | 3 | 42 | 3 | 17210696 | ||
| Pubmed | Role for Akt3/protein kinase Bgamma in attainment of normal brain size. | 1.64e-09 | 3 | 42 | 3 | 15713641 | |
| Pubmed | 4.32e-09 | 17 | 42 | 4 | 23251686 | ||
| Pubmed | 5.55e-09 | 18 | 42 | 4 | 33514739 | ||
| Pubmed | Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos. | 6.54e-09 | 4 | 42 | 3 | 31552693 | |
| Pubmed | Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass. | 6.54e-09 | 4 | 42 | 3 | 19933838 | |
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 21242979 | ||
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 19435822 | ||
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 21507933 | ||
| Pubmed | Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain. | 6.54e-09 | 4 | 42 | 3 | 26227811 | |
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 17942896 | ||
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 30567482 | ||
| Pubmed | 6.54e-09 | 4 | 42 | 3 | 21763505 | ||
| Pubmed | The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt. | 1.63e-08 | 5 | 42 | 3 | 20059950 | |
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 9512493 | ||
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 27938661 | ||
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 26855332 | ||
| Pubmed | Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. | 1.63e-08 | 5 | 42 | 3 | 17442925 | |
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 22814751 | ||
| Pubmed | Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. | 1.63e-08 | 5 | 42 | 3 | 19289493 | |
| Pubmed | Platelet-derived growth factor protects neurons against gp120-mediated toxicity. | 1.63e-08 | 5 | 42 | 3 | 18300076 | |
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 25246356 | ||
| Pubmed | Brown fat organogenesis and maintenance requires AKT1 and AKT2. | 1.63e-08 | 5 | 42 | 3 | 30833219 | |
| Pubmed | 1.63e-08 | 5 | 42 | 3 | 36640312 | ||
| Pubmed | Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms. | 1.63e-08 | 5 | 42 | 3 | 26996309 | |
| Pubmed | Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. | 3.27e-08 | 6 | 42 | 3 | 24642468 | |
| Pubmed | mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. | 3.27e-08 | 6 | 42 | 3 | 31996678 | |
| Pubmed | KCTD20, a relative of BTBD10, is a positive regulator of Akt. | 3.27e-08 | 6 | 42 | 3 | 24156551 | |
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 14749824 | ||
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 23746211 | ||
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 12176997 | ||
| Pubmed | Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis. | 3.27e-08 | 6 | 42 | 3 | 29038421 | |
| Pubmed | Akt Regulates Sox10 Expression to Control Oligodendrocyte Differentiation via Phosphorylating FoxO1. | 3.27e-08 | 6 | 42 | 3 | 34385359 | |
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 15616007 | ||
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 23673657 | ||
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 22107784 | ||
| Pubmed | Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family. | 3.27e-08 | 6 | 42 | 3 | 11707444 | |
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 21606541 | ||
| Pubmed | Protein kinase B alpha/Akt1 regulates placental development and fetal growth. | 3.27e-08 | 6 | 42 | 3 | 12783884 | |
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 18160256 | ||
| Pubmed | AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. | 3.27e-08 | 6 | 42 | 3 | 17439945 | |
| Pubmed | 3.27e-08 | 6 | 42 | 3 | 20186503 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 23968884 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 19261608 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 23604117 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 23811558 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 17634444 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 16287854 | ||
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 21697490 | ||
| Pubmed | The E3 ligase TRAF6 regulates Akt ubiquitination and activation. | 5.71e-08 | 7 | 42 | 3 | 19713527 | |
| Pubmed | 5.71e-08 | 7 | 42 | 3 | 21295499 | ||
| Pubmed | 9.13e-08 | 8 | 42 | 3 | 16841089 | ||
| Pubmed | 9.13e-08 | 8 | 42 | 3 | 18826950 | ||
| Pubmed | Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation. | 9.13e-08 | 8 | 42 | 3 | 20816796 | |
| Pubmed | 9.13e-08 | 8 | 42 | 3 | 11208609 | ||
| Pubmed | 9.13e-08 | 8 | 42 | 3 | 20040596 | ||
| Pubmed | 9.13e-08 | 8 | 42 | 3 | 24469921 | ||
| Pubmed | HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2. | 9.13e-08 | 8 | 42 | 3 | 22904195 | |
| Pubmed | The AKT isoforms 1 and 2 drive B cell fate decisions during the germinal center response. | 1.37e-07 | 9 | 42 | 3 | 31767615 | |
| Pubmed | 1.37e-07 | 9 | 42 | 3 | 16962829 | ||
| Pubmed | DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA. | 1.37e-07 | 9 | 42 | 3 | 15678105 | |
| Pubmed | 1.37e-07 | 9 | 42 | 3 | 21765914 | ||
| Pubmed | Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. | 1.46e-07 | 39 | 42 | 4 | 16510873 | |
| Interaction | RPS6KA1 interactions | 4.09e-10 | 228 | 39 | 9 | int:RPS6KA1 | |
| Interaction | RELA interactions | 3.39e-06 | 485 | 39 | 8 | int:RELA | |
| Interaction | RPS6KA3 interactions | 4.46e-06 | 226 | 39 | 6 | int:RPS6KA3 | |
| Interaction | TCL1A interactions | 5.77e-06 | 61 | 39 | 4 | int:TCL1A | |
| Interaction | KAT2B interactions | 9.10e-06 | 256 | 39 | 6 | int:KAT2B | |
| Interaction | BTBD10 interactions | 1.01e-05 | 22 | 39 | 3 | int:BTBD10 | |
| Interaction | F8 interactions | 1.50e-05 | 25 | 39 | 3 | int:F8 | |
| Interaction | TP73 interactions | 1.79e-05 | 169 | 39 | 5 | int:TP73 | |
| Interaction | AKT3 interactions | 2.17e-05 | 85 | 39 | 4 | int:AKT3 | |
| Interaction | ARRB1 interactions | 2.41e-05 | 304 | 39 | 6 | int:ARRB1 | |
| Interaction | NFKB1 interactions | 2.54e-05 | 307 | 39 | 6 | int:NFKB1 | |
| Interaction | AKT1S1 interactions | 3.20e-05 | 32 | 39 | 3 | int:AKT1S1 | |
| Interaction | EIF4EBP1 interactions | 3.22e-05 | 94 | 39 | 4 | int:EIF4EBP1 | |
| Interaction | CUL1 interactions | 3.47e-05 | 876 | 39 | 9 | int:CUL1 | |
| Interaction | PPP2CA interactions | 3.49e-05 | 484 | 39 | 7 | int:PPP2CA | |
| Interaction | FOXO4 interactions | 4.20e-05 | 35 | 39 | 3 | int:FOXO4 | |
| Interaction | PDPK1 interactions | 4.30e-05 | 203 | 39 | 5 | int:PDPK1 | |
| Interaction | RASSF1 interactions | 4.61e-05 | 103 | 39 | 4 | int:RASSF1 | |
| Interaction | MTCP1 interactions | 5.45e-05 | 6 | 39 | 2 | int:MTCP1 | |
| Interaction | RAB3D interactions | 6.79e-05 | 41 | 39 | 3 | int:RAB3D | |
| Interaction | XAF1 interactions | 7.30e-05 | 42 | 39 | 3 | int:XAF1 | |
| Interaction | TOPBP1 interactions | 7.59e-05 | 117 | 39 | 4 | int:TOPBP1 | |
| Interaction | CDKN1A interactions | 7.74e-05 | 375 | 39 | 6 | int:CDKN1A | |
| Interaction | SGK2 interactions | 7.84e-05 | 43 | 39 | 3 | int:SGK2 | |
| Interaction | FBXO31 interactions | 8.40e-05 | 44 | 39 | 3 | int:FBXO31 | |
| Interaction | RBBP8 interactions | 8.92e-05 | 122 | 39 | 4 | int:RBBP8 | |
| Interaction | CHEK1 interactions | 1.05e-04 | 245 | 39 | 5 | int:CHEK1 | |
| Interaction | UCHL1 interactions | 1.22e-04 | 253 | 39 | 5 | int:UCHL1 | |
| Interaction | UBE2S interactions | 1.44e-04 | 138 | 39 | 4 | int:UBE2S | |
| Interaction | PARP1 interactions | 1.51e-04 | 1316 | 39 | 10 | int:PARP1 | |
| Interaction | CHSY1 interactions | 1.55e-04 | 54 | 39 | 3 | int:CHSY1 | |
| Interaction | AKT1 interactions | 1.60e-04 | 617 | 39 | 7 | int:AKT1 | |
| Interaction | AKT2 interactions | 1.65e-04 | 143 | 39 | 4 | int:AKT2 | |
| Interaction | RPS6KB1 interactions | 1.65e-04 | 143 | 39 | 4 | int:RPS6KB1 | |
| Interaction | EMSY interactions | 1.74e-04 | 145 | 39 | 4 | int:EMSY | |
| Interaction | CLASP2 interactions | 1.83e-04 | 147 | 39 | 4 | int:CLASP2 | |
| Interaction | RPE interactions | 1.92e-04 | 58 | 39 | 3 | int:RPE | |
| Interaction | HSP90B1 interactions | 2.20e-04 | 650 | 39 | 7 | int:HSP90B1 | |
| Interaction | CCDC168 interactions | 2.38e-04 | 12 | 39 | 2 | int:CCDC168 | |
| Interaction | CCNA1 interactions | 2.46e-04 | 63 | 39 | 3 | int:CCNA1 | |
| Interaction | DNAJB1 interactions | 2.57e-04 | 297 | 39 | 5 | int:DNAJB1 | |
| Interaction | POLR1B interactions | 2.66e-04 | 162 | 39 | 4 | int:POLR1B | |
| Interaction | PAEP interactions | 3.21e-04 | 69 | 39 | 3 | int:PAEP | |
| Interaction | SPDL1 interactions | 3.36e-04 | 315 | 39 | 5 | int:SPDL1 | |
| Interaction | PSMD6 interactions | 3.46e-04 | 317 | 39 | 5 | int:PSMD6 | |
| Interaction | RFC2 interactions | 3.49e-04 | 174 | 39 | 4 | int:RFC2 | |
| Interaction | MYOG interactions | 3.64e-04 | 72 | 39 | 3 | int:MYOG | |
| Interaction | EGR1 interactions | 3.64e-04 | 72 | 39 | 3 | int:EGR1 | |
| Interaction | NBN interactions | 4.22e-04 | 183 | 39 | 4 | int:NBN | |
| Interaction | H2BC26 interactions | 4.22e-04 | 183 | 39 | 4 | int:H2BC26 | |
| Interaction | HSP90AB1 interactions | 4.24e-04 | 960 | 39 | 8 | int:HSP90AB1 | |
| Interaction | ZNF175 interactions | 4.30e-04 | 16 | 39 | 2 | int:ZNF175 | |
| Interaction | NDNF interactions | 4.30e-04 | 16 | 39 | 2 | int:NDNF | |
| Interaction | H2BC11 interactions | 4.49e-04 | 186 | 39 | 4 | int:H2BC11 | |
| Interaction | GPC4 interactions | 4.79e-04 | 79 | 39 | 3 | int:GPC4 | |
| Interaction | CLIP3 interactions | 4.87e-04 | 17 | 39 | 2 | int:CLIP3 | |
| Interaction | PMS2 interactions | 4.97e-04 | 80 | 39 | 3 | int:PMS2 | |
| Interaction | NUDT1 interactions | 5.15e-04 | 81 | 39 | 3 | int:NUDT1 | |
| Interaction | POLR1E interactions | 5.44e-04 | 350 | 39 | 5 | int:POLR1E | |
| Interaction | TP53I3 interactions | 5.47e-04 | 18 | 39 | 2 | int:TP53I3 | |
| Interaction | ZSWIM7 interactions | 5.47e-04 | 18 | 39 | 2 | int:ZSWIM7 | |
| Interaction | HSP90AA1 interactions | 5.54e-04 | 1263 | 39 | 9 | int:HSP90AA1 | |
| Interaction | PLEKHO1 interactions | 5.73e-04 | 84 | 39 | 3 | int:PLEKHO1 | |
| Interaction | NEDD4 interactions | 5.76e-04 | 544 | 39 | 6 | int:NEDD4 | |
| Interaction | METTL21C interactions | 6.11e-04 | 19 | 39 | 2 | int:METTL21C | |
| Interaction | ACAP1 interactions | 6.11e-04 | 19 | 39 | 2 | int:ACAP1 | |
| Interaction | BLVRA interactions | 6.14e-04 | 86 | 39 | 3 | int:BLVRA | |
| Interaction | NFKBIB interactions | 6.14e-04 | 86 | 39 | 3 | int:NFKBIB | |
| Interaction | SP1 interactions | 6.58e-04 | 365 | 39 | 5 | int:SP1 | |
| Interaction | CCL14 interactions | 6.78e-04 | 20 | 39 | 2 | int:CCL14 | |
| Interaction | FBXO9 interactions | 6.78e-04 | 20 | 39 | 2 | int:FBXO9 | |
| Interaction | GNL3 interactions | 6.83e-04 | 368 | 39 | 5 | int:GNL3 | |
| Interaction | ING3 interactions | 7.01e-04 | 90 | 39 | 3 | int:ING3 | |
| Interaction | RAD50 interactions | 7.08e-04 | 371 | 39 | 5 | int:RAD50 | |
| Interaction | ADAMTS17 interactions | 7.49e-04 | 21 | 39 | 2 | int:ADAMTS17 | |
| Interaction | ZPBP2 interactions | 7.49e-04 | 21 | 39 | 2 | int:ZPBP2 | |
| Interaction | KCTD20 interactions | 7.49e-04 | 21 | 39 | 2 | int:KCTD20 | |
| Interaction | SIRT3 interactions | 7.71e-04 | 93 | 39 | 3 | int:SIRT3 | |
| Interaction | PIK3CB interactions | 7.71e-04 | 93 | 39 | 3 | int:PIK3CB | |
| Interaction | CASP3 interactions | 7.87e-04 | 216 | 39 | 4 | int:CASP3 | |
| Interaction | BABAM2 interactions | 8.20e-04 | 95 | 39 | 3 | int:BABAM2 | |
| Interaction | CCL8 interactions | 8.23e-04 | 22 | 39 | 2 | int:CCL8 | |
| Interaction | REL interactions | 8.66e-04 | 388 | 39 | 5 | int:REL | |
| Interaction | CDK1 interactions | 8.80e-04 | 590 | 39 | 6 | int:CDK1 | |
| Interaction | C6orf15 interactions | 9.00e-04 | 23 | 39 | 2 | int:C6orf15 | |
| Interaction | POLQ interactions | 9.00e-04 | 23 | 39 | 2 | int:POLQ | |
| Interaction | RHNO1 interactions | 9.00e-04 | 23 | 39 | 2 | int:RHNO1 | |
| Interaction | ERCC6 interactions | 9.01e-04 | 224 | 39 | 4 | int:ERCC6 | |
| Interaction | POLR3H interactions | 9.24e-04 | 99 | 39 | 3 | int:POLR3H | |
| Interaction | MCPH1 interactions | 9.79e-04 | 101 | 39 | 3 | int:MCPH1 | |
| Interaction | TMEM62 interactions | 9.80e-04 | 24 | 39 | 2 | int:TMEM62 | |
| Interaction | ST6GALNAC4 interactions | 9.80e-04 | 24 | 39 | 2 | int:ST6GALNAC4 | |
| Cytoband | 19p13.2 | 1.22e-03 | 229 | 42 | 3 | 19p13.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | 4.49e-03 | 1192 | 42 | 5 | chr19q13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr12q23 | 8.38e-03 | 150 | 42 | 2 | chr12q23 | |
| GeneFamily | Ankyrin repeat domain containing|Death associated protein kinases | 3.63e-05 | 5 | 35 | 2 | 1021 | |
| GeneFamily | PDZ domain containing | 3.13e-03 | 152 | 35 | 3 | 1220 | |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | 7.30e-03 | 206 | 35 | 3 | 682 | |
| Coexpression | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 5.84e-07 | 101 | 42 | 5 | M15356 | |
| Coexpression | MARKEY_RB1_CHRONIC_LOF_UP | 3.34e-05 | 114 | 42 | 4 | M2895 | |
| Coexpression | MARKEY_RB1_CHRONIC_LOF_UP | 3.58e-05 | 116 | 42 | 4 | MM1090 | |
| Coexpression | MARTIN_INTERACT_WITH_HDAC | 3.91e-05 | 41 | 42 | 3 | M15154 | |
| ToppCell | wk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung | 2.01e-05 | 171 | 42 | 4 | b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a | |
| ToppCell | droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.21e-05 | 175 | 42 | 4 | 31f0fb2e47e357dbf9c15436b7df85b3c370ded7 | |
| ToppCell | PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 2.26e-05 | 176 | 42 | 4 | d30241fb8119834d6e7b59efec3f92fc7a3d1247 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 2.80e-05 | 186 | 42 | 4 | b45cce768e4bf91da194fd9660cab7520dfb15ac | |
| ToppCell | droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.23e-05 | 193 | 42 | 4 | fe451b3295d77b2bd1ac25cf29310c85835a45fe | |
| ToppCell | PBMC-Control-cDC_5|Control / Compartment, Disease Groups and Clusters | 3.23e-05 | 193 | 42 | 4 | 53ddee444dcfb9fe568e9e8fb64bc8304c262530 | |
| ToppCell | Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations | 3.57e-05 | 198 | 42 | 4 | 62059185afdf66126a6fbc899ce611c47e7a0feb | |
| ToppCell | Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 3.57e-05 | 198 | 42 | 4 | d6812494874be0c14361ac2ac3e418b335bb8f55 | |
| ToppCell | Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 3.72e-05 | 200 | 42 | 4 | a4ec0e80f5422b91b85264a9bb74568dd577e285 | |
| Drug | Clenbuterol | 1.03e-07 | 24 | 42 | 4 | ctd:D002976 | |
| Drug | Dobutamine | 3.19e-07 | 78 | 42 | 5 | ctd:D004280 | |
| Drug | Homocysteine | 1.48e-06 | 195 | 42 | 6 | ctd:D006710 | |
| Drug | Butyrates | 2.16e-06 | 208 | 42 | 6 | ctd:D002087 | |
| Drug | MolPort-016-580-972 | 2.35e-06 | 51 | 42 | 4 | CID009938589 | |
| Drug | dioscin | 2.74e-06 | 53 | 42 | 4 | ctd:C019357 | |
| Drug | tanespimycin | 3.43e-06 | 56 | 42 | 4 | ctd:C112765 | |
| Drug | NSC302991 | 3.43e-06 | 353 | 42 | 7 | CID000002538 | |
| Drug | Fenretinide | 6.36e-06 | 251 | 42 | 6 | ctd:D017313 | |
| Drug | Nexus | 8.65e-06 | 152 | 42 | 5 | CID000098527 | |
| Drug | wortmannin | 9.05e-06 | 267 | 42 | 6 | ctd:C009687 | |
| Drug | 4'-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol | 9.95e-06 | 3 | 42 | 2 | ctd:C569748 | |
| Drug | Akt inhibitor IV | 1.15e-05 | 24 | 42 | 3 | CID002326992 | |
| Drug | Oxidopamine | 1.21e-05 | 163 | 42 | 5 | ctd:D016627 | |
| Drug | AC1L2Y08 | 1.28e-05 | 432 | 42 | 7 | CID000105082 | |
| Drug | N-vinyl-2-pyrrolidinone | 1.47e-05 | 26 | 42 | 3 | ctd:C042670 | |
| Drug | 1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl)-piperazine | 1.99e-05 | 4 | 42 | 2 | ctd:C505382 | |
| Drug | testosterone-3-carboxymethyloxime-bovine serum albumin conjugate | 2.24e-05 | 185 | 42 | 5 | ctd:C045037 | |
| Drug | Piracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A | 2.61e-05 | 191 | 42 | 5 | 2861_DN | |
| Drug | pifithrin | 2.82e-05 | 95 | 42 | 4 | ctd:C121565 | |
| Drug | Aspirin | 2.86e-05 | 678 | 42 | 8 | ctd:D001241 | |
| Drug | Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A | 3.10e-05 | 198 | 42 | 5 | 3260_UP | |
| Drug | AC1OAGKB | 3.10e-05 | 198 | 42 | 5 | CID006857406 | |
| Drug | pyrazolo(3,4-d)pyrimidine | 3.19e-05 | 98 | 42 | 4 | ctd:C014175 | |
| Drug | cacalol | 3.31e-05 | 5 | 42 | 2 | ctd:C497192 | |
| Drug | PB28 compound | 3.31e-05 | 5 | 42 | 2 | ctd:C513937 | |
| Drug | Glutathione Diethyl Ester | 3.31e-05 | 5 | 42 | 2 | CID000175702 | |
| Drug | Brefeldin A | 3.67e-05 | 35 | 42 | 3 | ctd:D020126 | |
| Drug | demethoxycurcumin | 4.71e-05 | 38 | 42 | 3 | ctd:C050229 | |
| Drug | Hydroxymercuribenzoates | 4.96e-05 | 6 | 42 | 2 | ctd:D006902 | |
| Drug | wuzi yanzong | 4.96e-05 | 6 | 42 | 2 | ctd:C528421 | |
| Drug | dichloromethanediamine | 5.27e-05 | 539 | 42 | 7 | CID005311048 | |
| Drug | NSC693702 | 5.93e-05 | 41 | 42 | 3 | CID000003451 | |
| Drug | withaferin A | 6.37e-05 | 42 | 42 | 3 | ctd:C009684 | |
| Drug | Palmitic Acid | 7.99e-05 | 124 | 42 | 4 | ctd:D019308 | |
| Drug | Metformin | 8.70e-05 | 400 | 42 | 6 | ctd:D008687 | |
| Drug | 1-nitropyrene | 9.19e-05 | 249 | 42 | 5 | ctd:C032668 | |
| Drug | 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole | 9.24e-05 | 8 | 42 | 2 | ctd:C492322 | |
| Drug | 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one | 9.24e-05 | 8 | 42 | 2 | ctd:C532657 | |
| Drug | zerumbone | 9.53e-05 | 48 | 42 | 3 | ctd:C403304 | |
| Drug | pterostilbene | 9.60e-05 | 130 | 42 | 4 | ctd:C107773 | |
| Drug | Asbestos, Amphibole | 9.89e-05 | 131 | 42 | 4 | ctd:D017636 | |
| Drug | methylselenic acid | 1.02e-04 | 412 | 42 | 6 | ctd:C008493 | |
| Drug | Ceruletide | 1.14e-04 | 51 | 42 | 3 | ctd:D002108 | |
| Drug | fumaric acid | 1.19e-04 | 9 | 42 | 2 | ctd:C032005 | |
| Drug | 5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one | 1.19e-04 | 9 | 42 | 2 | ctd:C524883 | |
| Drug | Bortezomib | 1.26e-04 | 838 | 42 | 8 | ctd:D000069286 | |
| Drug | ursolic acid | 1.28e-04 | 53 | 42 | 3 | ctd:C005466 | |
| Drug | Imatinib Mesylate | 1.31e-04 | 141 | 42 | 4 | ctd:D000068877 | |
| Drug | borane | 1.32e-04 | 269 | 42 | 5 | CID000006331 | |
| Drug | gemcitabine | 1.34e-04 | 270 | 42 | 5 | ctd:C056507 | |
| Drug | 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol | 1.36e-04 | 54 | 42 | 3 | ctd:C054649 | |
| Drug | mangiferin | 1.39e-04 | 143 | 42 | 4 | ctd:C013592 | |
| Drug | V0509 | 1.39e-04 | 272 | 42 | 5 | CID000102191 | |
| Drug | triciribine | 1.48e-04 | 10 | 42 | 2 | ctd:C023764 | |
| Drug | malvidin-3-glucoside | 1.48e-04 | 10 | 42 | 2 | ctd:C458419 | |
| Drug | Z-LLnV | 1.51e-04 | 56 | 42 | 3 | CID009868928 | |
| Drug | sorafenib | 1.62e-04 | 149 | 42 | 4 | ctd:C471405 | |
| Drug | prolinedithiocarbamate | 1.77e-04 | 59 | 42 | 3 | ctd:C066229 | |
| Drug | Sirolimus | 1.78e-04 | 456 | 42 | 6 | ctd:D020123 | |
| Drug | MMEA | 1.81e-04 | 11 | 42 | 2 | CID000125823 | |
| Drug | Geraniin | 1.81e-04 | 11 | 42 | 2 | ctd:C024603 | |
| Drug | CCG 1423 | 1.81e-04 | 11 | 42 | 2 | ctd:C523455 | |
| Drug | UCN-01 | 1.84e-04 | 154 | 42 | 4 | CID000072271 | |
| Drug | Saponins | 1.95e-04 | 61 | 42 | 3 | ctd:D012503 | |
| Drug | tauroursodeoxycholic acid | 1.99e-04 | 157 | 42 | 4 | ctd:C031655 | |
| Drug | 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosphate | 2.17e-04 | 12 | 42 | 2 | ctd:C473217 | |
| Drug | N(1),N(11)-diethylnorspermine | 2.17e-04 | 12 | 42 | 2 | ctd:C059685 | |
| Drug | osthol | 2.17e-04 | 12 | 42 | 2 | ctd:C046627 | |
| Drug | Thioctic Acid | 2.29e-04 | 163 | 42 | 4 | ctd:D008063 | |
| Drug | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | 2.35e-04 | 65 | 42 | 3 | ctd:D002259 | |
| Drug | zinc chromate | 2.56e-04 | 13 | 42 | 2 | ctd:C023616 | |
| Drug | diallyl trisulfide | 2.57e-04 | 168 | 42 | 4 | ctd:C042577 | |
| Drug | pyrithione zinc | 2.58e-04 | 67 | 42 | 3 | ctd:C010423 | |
| Drug | AC1L1CV3 | 2.63e-04 | 169 | 42 | 4 | CID000002076 | |
| Drug | phenylmethylpyrazolone | 2.69e-04 | 68 | 42 | 3 | ctd:C005435 | |
| Drug | 3,5-bis(2-fluorobenzylidene)piperidin-4-one | 2.93e-04 | 70 | 42 | 3 | ctd:C524042 | |
| Drug | antimycin | 2.98e-04 | 14 | 42 | 2 | ctd:C032456 | |
| Drug | thiadiazolidinone | 2.98e-04 | 14 | 42 | 2 | CID000443041 | |
| Drug | alvocidib | 3.06e-04 | 71 | 42 | 3 | ctd:C077990 | |
| Drug | aristolochic acid I | 3.21e-04 | 178 | 42 | 4 | ctd:C000228 | |
| Drug | pifithrin-alpha | 3.32e-04 | 73 | 42 | 3 | CID000004817 | |
| Drug | sebacate | 3.42e-04 | 181 | 42 | 4 | CID000005192 | |
| Drug | SNX 2112 | 3.44e-04 | 15 | 42 | 2 | ctd:C534922 | |
| Drug | 2-Benzyloxybenzaldehyde | 3.44e-04 | 15 | 42 | 2 | CID000344784 | |
| Drug | C3H2N2O3S | 3.45e-04 | 74 | 42 | 3 | CID000448652 | |
| Drug | Fungal Polysaccharides | 3.45e-04 | 74 | 42 | 3 | ctd:D062610 | |
| Drug | R A J | 3.45e-04 | 74 | 42 | 3 | CID011497471 | |
| Drug | Rotenone | 3.62e-04 | 978 | 42 | 8 | ctd:D012402 | |
| Drug | Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A | 3.86e-04 | 187 | 42 | 4 | 4589_UP | |
| Drug | EKB 569 | 3.92e-04 | 16 | 42 | 2 | ctd:C413879 | |
| Drug | methyl caffeate | 3.92e-04 | 16 | 42 | 2 | ctd:C042405 | |
| Drug | Clostridium difficile lethal toxin B | 3.92e-04 | 16 | 42 | 2 | ctd:C488583 | |
| Drug | LY294002 | 3.98e-04 | 748 | 42 | 7 | CID000003973 | |
| Drug | methylseleninic acid | 4.03e-04 | 78 | 42 | 3 | CID000161597 | |
| Drug | Amiloride | 4.03e-04 | 78 | 42 | 3 | ctd:D000584 | |
| Drug | Lobelanidine hydrochloride [6112-86-3]; Down 200; 10.6uM; PC3; HT_HG-U133A | 4.10e-04 | 190 | 42 | 4 | 5080_DN | |
| Drug | NSC236997 | 4.35e-04 | 539 | 42 | 6 | CID000005300 | |
| Drug | wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA | 4.35e-04 | 193 | 42 | 4 | 1081_DN | |
| Drug | Adenosine Triphosphate | 4.35e-04 | 193 | 42 | 4 | ctd:D000255 | |
| Disease | Mammary Carcinoma, Human | 4.44e-07 | 525 | 40 | 8 | C4704874 | |
| Disease | Mammary Neoplasms, Human | 4.44e-07 | 525 | 40 | 8 | C1257931 | |
| Disease | Mammary Neoplasms | 4.57e-07 | 527 | 40 | 8 | C1458155 | |
| Disease | prostate cancer (is_implicated_in) | 5.30e-07 | 117 | 40 | 5 | DOID:10283 (is_implicated_in) | |
| Disease | Breast Carcinoma | 5.34e-07 | 538 | 40 | 8 | C0678222 | |
| Disease | Malignant neoplasm of breast | 1.23e-06 | 1074 | 40 | 10 | C0006142 | |
| Disease | prostate adenocarcinoma (is_implicated_in) | 2.59e-06 | 20 | 40 | 3 | DOID:2526 (is_implicated_in) | |
| Disease | malignant astrocytoma (is_marker_for) | 4.01e-06 | 23 | 40 | 3 | DOID:3069 (is_marker_for) | |
| Disease | glioblastoma (is_implicated_in) | 4.58e-06 | 24 | 40 | 3 | DOID:3068 (is_implicated_in) | |
| Disease | Neoplasm of uncertain or unknown behavior of ovary | 8.23e-06 | 29 | 40 | 3 | C0496920 | |
| Disease | Ovarian Carcinoma | 9.13e-06 | 30 | 40 | 3 | C0029925 | |
| Disease | Neoplasm of uncertain or unknown behavior of breast | 2.37e-05 | 41 | 40 | 3 | C0496956 | |
| Disease | Breast adenocarcinoma | 2.37e-05 | 41 | 40 | 3 | C0858252 | |
| Disease | Malignant Neoplasms | 2.74e-05 | 128 | 40 | 4 | C0006826 | |
| Disease | ovarian neoplasm | 3.27e-05 | 134 | 40 | 4 | C0919267 | |
| Disease | Malignant neoplasm of ovary | 3.57e-05 | 137 | 40 | 4 | C1140680 | |
| Disease | white matter hyperintensity measurement | 5.33e-05 | 302 | 40 | 5 | EFO_0005665 | |
| Disease | Non-Small Cell Lung Carcinoma | 5.92e-05 | 156 | 40 | 4 | C0007131 | |
| Disease | lymphangioleiomyomatosis (is_marker_for) | 1.17e-04 | 12 | 40 | 2 | DOID:3319 (is_marker_for) | |
| Disease | Benign tumor of pancreas | 1.38e-04 | 13 | 40 | 2 | C0347284 | |
| Disease | alcoholic hepatitis (biomarker_via_orthology) | 2.70e-04 | 18 | 40 | 2 | DOID:12351 (biomarker_via_orthology) | |
| Disease | Pancreatic carcinoma | 3.02e-04 | 19 | 40 | 2 | C0235974 | |
| Disease | Adenocarcinoma of large intestine | 3.02e-04 | 96 | 40 | 3 | C1319315 | |
| Disease | Adenocarcinoma of prostate | 3.35e-04 | 20 | 40 | 2 | C0007112 | |
| Disease | alpha fetoprotein measurement | 3.41e-04 | 100 | 40 | 3 | EFO_0010583 | |
| Disease | Pancreatic Neoplasm | 3.41e-04 | 100 | 40 | 3 | C0030297 | |
| Disease | melanoma | 3.51e-04 | 248 | 40 | 4 | C0025202 | |
| Disease | Malignant neoplasm of pancreas | 3.61e-04 | 102 | 40 | 3 | C0346647 | |
| Disease | BREAST CANCER | 3.70e-04 | 21 | 40 | 2 | 114480 | |
| Disease | chronic myeloid leukemia (is_implicated_in) | 3.70e-04 | 21 | 40 | 2 | DOID:8552 (is_implicated_in) | |
| Disease | HIV Coinfection | 3.72e-04 | 103 | 40 | 3 | C4505456 | |
| Disease | HIV Infections | 3.72e-04 | 103 | 40 | 3 | C0019693 | |
| Disease | type 2 diabetes mellitus (implicated_via_orthology) | 3.93e-04 | 105 | 40 | 3 | DOID:9352 (implicated_via_orthology) | |
| Disease | Nasopharyngeal carcinoma | 4.07e-04 | 22 | 40 | 2 | C2931822 | |
| Disease | Respiratory Hypersensitivity | 4.07e-04 | 22 | 40 | 2 | C0035228 | |
| Disease | hepatocellular carcinoma (biomarker_via_orthology) | 4.27e-04 | 108 | 40 | 3 | DOID:684 (biomarker_via_orthology) | |
| Disease | Bipolar Disorder | 4.46e-04 | 477 | 40 | 5 | C0005586 | |
| Disease | cancer (implicated_via_orthology) | 4.70e-04 | 268 | 40 | 4 | DOID:162 (implicated_via_orthology) | |
| Disease | Neoplasm of the genitourinary tract | 4.85e-04 | 24 | 40 | 2 | cv:C0042065 | |
| Disease | Brugada Syndrome (disorder) | 4.85e-04 | 24 | 40 | 2 | C1142166 | |
| Disease | Malignant tumor of breast | 6.16e-04 | 27 | 40 | 2 | cv:C0006142 | |
| Disease | Breast neoplasm | 6.16e-04 | 27 | 40 | 2 | cv:C1458155 | |
| Disease | Familial cancer of breast | 6.16e-04 | 27 | 40 | 2 | cv:C0346153 | |
| Disease | melanoma (is_implicated_in) | 9.78e-04 | 34 | 40 | 2 | DOID:1909 (is_implicated_in) | |
| Disease | facial emotion recognition measurement | 1.04e-03 | 35 | 40 | 2 | EFO_0008329 | |
| Disease | endometrial cancer (is_implicated_in) | 1.10e-03 | 36 | 40 | 2 | DOID:1380 (is_implicated_in) | |
| Disease | colon cancer (is_implicated_in) | 1.10e-03 | 36 | 40 | 2 | DOID:219 (is_implicated_in) | |
| Disease | Parkinson's disease (implicated_via_orthology) | 1.26e-03 | 157 | 40 | 3 | DOID:14330 (implicated_via_orthology) | |
| Disease | colorectal cancer (is_marker_for) | 1.26e-03 | 157 | 40 | 3 | DOID:9256 (is_marker_for) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| SETDTRYFDEEFTAQ | 431 | P31749 | |
| TSEVDTRYFDDEFTA | 431 | P31751 | |
| SITSYYSAEDRDETF | 311 | Q6NVV9 | |
| TAEVTFDDTDSYVIT | 776 | Q9H7T0 | |
| EEDFSGDFREYSTVS | 1931 | P13611 | |
| SSSDTESDFYEEIEV | 111 | P49640 | |
| FFVTLDETEEGYRSE | 416 | P50416 | |
| LSSDEEYYVEESRSA | 171 | Q5BKX8 | |
| YDFTSTTTNEEDLFS | 426 | Q96DT6 | |
| VTSETDTRYFDEEFT | 426 | Q9Y243 | |
| DTRYFDEEFTAQTIT | 431 | Q9Y243 | |
| YESSVSEDFLSSVDE | 3321 | Q01484 | |
| FYEETESSDDVEVLT | 41 | Q96K31 | |
| FSFYSRTETFEDEGA | 361 | Q5TGI0 | |
| VFSERTEESSAVQYF | 136 | Q86X55 | |
| FSTEEIEDEYVTDYT | 2136 | Q9Y6V0 | |
| EESYDTESEFTEFTE | 286 | P25963 | |
| LESEDDTSYFDTRSD | 666 | Q9Y2H9 | |
| FSSAVYFAEVDRVDS | 326 | Q96RP8 | |
| YETVVDTSEEDSFSL | 296 | P51587 | |
| DTVETFGTTSYYDDV | 6 | P51677 | |
| AVSYDFDEEFFSQTS | 241 | Q9UIK4 | |
| FLADTERFYTRESTE | 236 | Q13616 | |
| SEDDTSYFDTRSERY | 806 | Q6P0Q8 | |
| SFYEGEDFSETLTRA | 311 | P11021 | |
| EVSYSFFDASEDILT | 276 | Q9Y5E1 | |
| IFTEEDTDETVESYE | 1511 | Q2WGJ9 | |
| RTASYEEEVETYFFE | 36 | O75691 | |
| FASVSETFETKVDDY | 1156 | O95602 | |
| DTFFDECYFEDVTST | 471 | Q7L1I2 | |
| EDATFSEYSEKETEF | 1316 | P57071 | |
| SVEFEVESLDSEDYS | 246 | Q00987 | |
| SRFSAEFDFRTYDSE | 321 | P07225 | |
| KATVFTDEESYSFES | 576 | Q9UQ84 | |
| TDEESYSFESSKFTR | 581 | Q9UQ84 | |
| SYSEEEFDVLSESAV | 281 | Q9UEE5 | |
| FEETDLTYQVSESDS | 241 | P11831 | |
| FSADFTIDYSIFESE | 46 | Q8WWF1 | |
| TVSFDEESYEEFRSS | 116 | Q96LP6 | |
| DTEVTALSEDEYFSA | 1541 | Q12888 | |
| EEIYSEFTASFTSVS | 596 | Q9UK13 | |
| LTVYSSEDGSEEFET | 361 | Q8TD43 | |
| SVSFEDVTVDFSREE | 26 | Q9Y473 | |
| YSVTFEDTAVDFTQE | 11 | Q96MR9 |