Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH6 DNAH11

7.83e-0518943GO:0008569
GeneOntologyMolecularFunctionactin filament binding

GJB6 ACTN4 ACTN1 ACTN2 ACTN3 FMNL2 FMNL3

9.90e-05227947GO:0051015
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

1.31e-044942GO:0005219
GeneOntologyMolecularFunctionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen

MIOX BCO1 TMLHE

2.43e-0426943GO:0016701
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNAH6 DNAH11

3.04e-0428943GO:0051959
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

3.25e-046942GO:0048763
GeneOntologyMolecularFunctionactin binding

KLHL1 GJB6 ACTN4 ACTN1 ACTN2 ACTN3 FMNL2 FMNL3 KLHL5

4.27e-04479949GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein binding

KLHL1 TTLL9 GJB6 ACTN4 PSMD10 ACTN1 ACTN2 ACTN3 FMNL2 FMNL3 KLHL5 NF1 TIAM1 DNAI7

6.08e-0410999414GO:0008092
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNAH6 DNAH11

6.99e-0437943GO:0045505
GeneOntologyMolecularFunctioncalcium ion binding

GNPTAB ACTN4 ACTN1 ACTN2 ACTN3 ADGRE2 RYR1 RYR2 FAT2 P4HTM PLCB4

7.82e-047499411GO:0005509
GeneOntologyMolecularFunctiondioxygenase activity

BCO1 RIOX2 P4HTM TMLHE

1.19e-0398944GO:0051213
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

DCAF1 AKT3 GAK BCKDK ARAF GRK3 TNK2 CDK11B

1.21e-03446948GO:0004674
GeneOntologyMolecularFunctiontransmembrane transporter binding

ACTN4 PSMD10 ACTN1 ACTN2 ACTN3

1.32e-03172945GO:0044325
GeneOntologyMolecularFunctionintegrin binding

ACTN4 ACTN1 ACTN2 ACTN3 ITGAX

1.43e-03175945GO:0005178
GeneOntologyMolecularFunctionprotein serine kinase activity

DCAF1 AKT3 GAK BCKDK ARAF TNK2 CDK11B

1.64e-03363947GO:0106310
GeneOntologyBiologicalProcesscilium movement involved in cell motility

SEPTIN4 TTLL9 BBS2 APOB DZIP1 DNAH14 RABL2B DNAH6 PRDM14 CFAP46 DNAH11

3.88e-092109611GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

SEPTIN4 TTLL9 BBS2 APOB DZIP1 DNAH14 RABL2B DNAH6 PRDM14 CFAP46 DNAH11

4.96e-092159611GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

SEPTIN4 TTLL9 BBS2 APOB DZIP1 DNAH14 RABL2B DNAH6 PRDM14 CFAP46 DNAH11

4.96e-092159611GO:0001539
GeneOntologyBiologicalProcesscilium movement

SEPTIN4 TTLL9 BBS2 APOB DZIP1 DNAH14 RABL2B DNAH6 PRDM14 CFAP46 DNAH11

3.68e-082619611GO:0003341
GeneOntologyBiologicalProcessmicrotubule-based movement

SEPTIN4 TTLL9 BBS2 COPG2 APOB DZIP1 DNAH14 RABL2B DNAI7 DNAH6 PRDM14 CFAP46 DNAH11

4.70e-074939613GO:0007018
GeneOntologyBiologicalProcessflagellated sperm motility

SEPTIN4 TTLL9 BBS2 APOB DZIP1 RABL2B PRDM14 DNAH11

2.53e-06186968GO:0030317
GeneOntologyBiologicalProcesssperm motility

SEPTIN4 TTLL9 BBS2 APOB DZIP1 RABL2B PRDM14 DNAH11

3.34e-06193968GO:0097722
GeneOntologyBiologicalProcesshomeostasis of number of cells within a tissue

AKT3 VPS54 COL14A1 PRDM14 VEGFA

3.90e-0651965GO:0048873
GeneOntologyBiologicalProcessmuscle cell development

ACTN4 ACTN1 ACTN2 ACTN3 TRIP10 RYR1 COL14A1 VEGFA

2.84e-05259968GO:0055001
GeneOntologyBiologicalProcessbrain morphogenesis

AKT3 GAK BBS2 NF1

7.95e-0549964GO:0048854
GeneOntologyBiologicalProcessmicrotubule-based process

SEPTIN4 TTLL9 BBS2 COPG2 APOB DZIP1 DNAH14 RABL2B CDK11B DNAI7 DNAH6 PRDM14 WDR62 CFAP46 DNAH11

1.07e-0410589615GO:0007017
GeneOntologyBiologicalProcesscell-substrate adhesion

ACTN4 ACTN1 ACTN2 ACTN3 ITGAX FAT2 NF1 TIAM1 VEGFA

1.25e-04410969GO:0031589
GeneOntologyBiologicalProcessanatomical structure homeostasis

AKT3 GJB6 BBS2 VPS54 NF1 COL14A1 PRDM14 VEGFA

1.67e-04334968GO:0060249
GeneOntologyBiologicalProcesstissue homeostasis

AKT3 GJB6 BBS2 VPS54 NF1 COL14A1 PRDM14 VEGFA

1.67e-04334968GO:0001894
GeneOntologyBiologicalProcesscell-matrix adhesion

ACTN1 ACTN2 ACTN3 ITGAX NF1 TIAM1 VEGFA

2.69e-04270967GO:0007160
GeneOntologyBiologicalProcessmuscle tissue development

GJB6 VPS54 ACTN2 ACTN3 TRIP10 RYR1 RYR2 NF1 COL14A1 VEGFA

2.72e-045589610GO:0060537
GeneOntologyCellularComponentpseudopodium

ACTN4 ACTN1 ACTN2 ACTN3

1.17e-0618954GO:0031143
GeneOntologyCellularComponentZ disc

ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 GRK3

5.80e-06151957GO:0030018
GeneOntologyCellularComponentI band

ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 GRK3

1.08e-05166957GO:0031674
GeneOntologyCellularComponentmotile cilium

SEPTIN4 TTLL9 BBS2 DNAH14 RABL2B GRK3 CFAP119 DNAH6 DNAH11

3.46e-05355959GO:0031514
GeneOntologyCellularComponentcilium

SEPTIN4 TTLL9 BBS2 CCDC178 DZIP1 DNAH14 RABL2B GRK3 TIAM1 CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

5.28e-058989514GO:0005929
GeneOntologyCellularComponentsmooth endoplasmic reticulum

APOB RYR1 RYR2 PLCB4

5.64e-0546954GO:0005790
GeneOntologyCellularComponentsupramolecular fiber

TTLL9 GJB6 ACTN4 ACTN1 ACTN2 ACTN3 TRIP10 DNAH14 RYR1 RYR2 GRK3 TIAM1 TNK2 DNAI7 DNAH6 DNAH11

7.71e-0511799516GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TTLL9 GJB6 ACTN4 ACTN1 ACTN2 ACTN3 TRIP10 DNAH14 RYR1 RYR2 GRK3 TIAM1 TNK2 DNAI7 DNAH6 DNAH11

8.35e-0511879516GO:0099081
GeneOntologyCellularComponentdynein complex

DNAH14 DNAI7 DNAH6 DNAH11

1.06e-0454954GO:0030286
GeneOntologyCellularComponent9+2 motile cilium

SEPTIN4 DNAH14 RABL2B GRK3 CFAP119 DNAH6 DNAH11

1.07e-04238957GO:0097729
GeneOntologyCellularComponentsarcomere

ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 GRK3

1.42e-04249957GO:0030017
GeneOntologyCellularComponentplatelet alpha granule lumen

ACTN4 ACTN1 ACTN2 VEGFA

2.46e-0467954GO:0031093
GeneOntologyCellularComponentmyofibril

ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 GRK3

2.49e-04273957GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 GRK3

3.59e-04290957GO:0043292
GeneOntologyCellularComponentcortical actin cytoskeleton

ACTN4 ACTN1 ACTN2 ACTN3

8.58e-0493954GO:0030864
GeneOntologyCellularComponentplatelet alpha granule

ACTN4 ACTN1 ACTN2 VEGFA

8.58e-0493954GO:0031091
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

8.98e-0410952GO:0014701
GeneOntologyCellularComponentinner dynein arm

DNAI7 DNAH6

8.98e-0410952GO:0036156
GeneOntologyCellularComponentcell cortex

SEPTIN4 ACTN4 ACTN1 ACTN2 ACTN3 TRIP10 RYR1

1.52e-03371957GO:0005938
GeneOntologyCellularComponentciliary basal body

TTLL9 BBS2 CCDC178 DZIP1 RABL2B

1.97e-03195955GO:0036064
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

TTLL9 GJB6 ACTN1 ACTN2 ACTN3 TRIP10 DNAH14 TIAM1 DNAI7 DNAH6 DNAH11

2.53e-038999511GO:0099513
GeneOntologyCellularComponentcortical cytoskeleton

ACTN4 ACTN1 ACTN2 ACTN3

2.86e-03129954GO:0030863
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

ACTN4 ACTN2

3.32e-0319952GO:0098871
DomainEF-hand_Ca_insen

ACTN4 ACTN1 ACTN2 ACTN3

9.75e-096964IPR014837
DomainEFhand_Ca_insen

ACTN4 ACTN1 ACTN2 ACTN3

9.75e-096964PF08726
DomainEF-hand-dom_pair

GNPTAB EFCAB13 ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 P4HTM PLCB4

2.21e-062879610IPR011992
DomainActinin_actin-bd_CS

ACTN4 ACTN1 ACTN2 ACTN3

5.38e-0623964IPR001589
DomainSpectrin

ACTN4 ACTN1 ACTN2 ACTN3

5.38e-0623964PF00435
DomainACTININ_2

ACTN4 ACTN1 ACTN2 ACTN3

5.38e-0623964PS00020
DomainACTININ_1

ACTN4 ACTN1 ACTN2 ACTN3

5.38e-0623964PS00019
Domain-

EFCAB13 ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 P4HTM PLCB4

7.96e-062619691.10.238.10
DomainARM-type_fold

DCAF1 CLTCL1 COPG2 APOB FMNL2 WDFY4 FMNL3 NF1 TTI1 USP35

9.62e-063399610IPR016024
DomainSpectrin_repeat

ACTN4 ACTN1 ACTN2 ACTN3

1.41e-0529964IPR002017
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3 VAV3

2.09e-0565965SM00033
DomainSpectrin/alpha-actinin

ACTN4 ACTN1 ACTN2 ACTN3

2.11e-0532964IPR018159
DomainSPEC

ACTN4 ACTN1 ACTN2 ACTN3

2.11e-0532964SM00150
DomainEF_HAND_2

GNPTAB EFCAB13 ACTN4 ACTN1 ACTN2 ACTN3 RYR2 P4HTM

2.52e-05231968PS50222
DomainEF_hand_dom

GNPTAB ACTN4 ACTN1 ACTN2 ACTN3 RYR1 RYR2 P4HTM

2.60e-05232968IPR002048
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3 VAV3

3.00e-0570965PF00307
Domain-

ACTN4 ACTN1 ACTN2 ACTN3 VAV3

3.22e-05719651.10.418.10
DomainCH

ACTN4 ACTN1 ACTN2 ACTN3 VAV3

3.68e-0573965PS50021
DomainCH-domain

ACTN4 ACTN1 ACTN2 ACTN3 VAV3

4.19e-0575965IPR001715
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH6 DNAH11

4.60e-0514963IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH6 DNAH11

4.60e-0514963IPR024743
DomainMT

DNAH14 DNAH6 DNAH11

4.60e-0514963PF12777
DomainAAA_8

DNAH14 DNAH6 DNAH11

4.60e-0514963PF12780
DomainDHC_fam

DNAH14 DNAH6 DNAH11

5.73e-0515963IPR026983
DomainDynein_heavy_dom

DNAH14 DNAH6 DNAH11

5.73e-0515963IPR004273
DomainDynein_heavy

DNAH14 DNAH6 DNAH11

5.73e-0515963PF03028
DomainRyanrecept_TM4-6

RYR1 RYR2

7.82e-053962IPR009460
DomainRyR

RYR1 RYR2

7.82e-053962PF02026
DomainRyanodine_rcpt

RYR1 RYR2

7.82e-053962IPR003032
DomainRR_TM4-6

RYR1 RYR2

7.82e-053962PF06459
DomainRyan_recept

RYR1 RYR2

7.82e-053962IPR013333
DomainEF-hand_1

GNPTAB ACTN4 ACTN1 ACTN2 ACTN3 RYR2

1.34e-04152966PF00036
DomainApc4_WD40_dom

WDR3 WDR17 WDR62

1.41e-0420963IPR024977
DomainANAPC4_WD40

WDR3 WDR17 WDR62

1.41e-0420963PF12894
DomainWD40_repeat_dom

DCAF1 BBS2 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

1.47e-04297968IPR017986
Domain-

DCAF1 BBS2 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

3.19e-043339682.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 BBS2 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

3.32e-04335968IPR015943
DomainRIH_assoc

RYR1 RYR2

3.87e-046962PF08454
DomainDUSP

USP20 USP4

3.87e-046962SM00695
DomainRIH_assoc-dom

RYR1 RYR2

3.87e-046962IPR013662
DomainRIH_dom

RYR1 RYR2

3.87e-046962IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2

3.87e-046962IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2

3.87e-046962IPR015925
Domain-

RYR1 RYR2

3.87e-0469621.25.10.30
DomainRYDR_ITPR

RYR1 RYR2

3.87e-046962PF01365
DomainDUSP

USP20 USP4

3.87e-046962PF06337
DomainRBD

ARAF TIAM1

3.87e-046962PF02196
DomainIns145_P3_rec

RYR1 RYR2

3.87e-046962PF08709
DomainRBD

ARAF TIAM1

5.40e-047962SM00455
Domain-

USP20 USP4

5.40e-0479623.30.2230.10
DomainDUSP

USP20 USP4

5.40e-047962PS51283
DomainRBD_dom

ARAF TIAM1

5.40e-047962IPR003116
DomainRBD

ARAF TIAM1

5.40e-047962PS50898
DomainPept_C19_DUSP

USP20 USP4

5.40e-047962IPR006615
DomainWD_REPEATS_1

DCAF1 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

5.79e-04278967PS00678
DomainWD_REPEATS_2

DCAF1 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

5.91e-04279967PS50082
DomainWD_REPEATS_REGION

DCAF1 WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

5.91e-04279967PS50294
DomainDrf_GBD

FMNL2 FMNL3

9.19e-049962PF06371
DomainFH3_dom

FMNL2 FMNL3

9.19e-049962IPR010472
DomainGTPase-bd

FMNL2 FMNL3

9.19e-049962IPR010473
DomainDrf_FH3

FMNL2 FMNL3

9.19e-049962PF06367
DomainDrf_FH3

FMNL2 FMNL3

9.19e-049962SM01139
DomainDrf_GBD

FMNL2 FMNL3

9.19e-049962SM01140
DomainMIR

RYR1 RYR2

1.15e-0310962PS50919
DomainMIR

RYR1 RYR2

1.15e-0310962PF02815
DomainMIR

RYR1 RYR2

1.15e-0310962SM00472
DomainMIR_motif

RYR1 RYR2

1.15e-0310962IPR016093
DomainEFh

ACTN4 ACTN1 ACTN2 ACTN3 RYR2

1.34e-03158965SM00054
DomainGBD/FH3_dom

FMNL2 FMNL3

1.40e-0311962IPR014768
DomainGBD_FH3

FMNL2 FMNL3

1.40e-0311962PS51232
DomainZnF_UBP

USP20 BRAP

1.40e-0311962SM00290
DomainWD40_repeat_CS

WDFY4 DENND3 WDR3 ERCC8 WDR17

1.58e-03164965IPR019775
DomainWD40

WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

2.20e-03259966PF00400
DomainDynein_heavy_dom-2

DNAH6 DNAH11

2.29e-0314962IPR013602
DomainZnf_UBP

USP20 BRAP

2.29e-0314962IPR001607
DomainDHC_N2

DNAH6 DNAH11

2.29e-0314962PF08393
DomainATPase_dyneun-rel_AAA

DNAH6 DNAH11

2.29e-0314962IPR011704
Domainzf-UBP

USP20 BRAP

2.29e-0314962PF02148
DomainZF_UBP

USP20 BRAP

2.29e-0314962PS50271
DomainAAA_5

DNAH6 DNAH11

2.29e-0314962PF07728
Domain-

ZNF136 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.56e-0367996103.30.160.60
DomainZnf_C2H2-like

ZNF136 ZNF622 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.56e-037969611IPR015880
DomainWD40

WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

2.60e-03268966SM00320
DomainFH2

FMNL2 FMNL3

2.63e-0315962PS51444
DomainFH2_Formin

FMNL2 FMNL3

2.63e-0315962IPR015425
DomainFH2

FMNL2 FMNL3

2.63e-0315962PF02181
DomainFH2

FMNL2 FMNL3

2.63e-0315962SM00498
DomainARM-like

DCAF1 COPG2 WDFY4 NF1 TTI1 USP35

2.70e-03270966IPR011989
DomainZnf_C2H2

ZNF136 ZNF622 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.79e-038059611IPR007087
DomainWD40_repeat

WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

2.80e-03272966IPR001680
DomainZnF_C2H2

ZNF136 ZNF622 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.87e-038089611SM00355
Domainzf-C2H2

ZNF136 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.96e-036939610PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF136 ZNF215 DZIP1 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.99e-036949610IPR013087
DomainKelch

KLHL1 KBTBD2 KLHL5

3.31e-0358963SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL1 KBTBD2 KLHL5

3.47e-0359963IPR011043
DomainBACK

KLHL1 KBTBD2 KLHL5

3.64e-0360963SM00875
DomainBACK

KLHL1 KBTBD2 KLHL5

3.82e-0361963PF07707
DomainBACK

KLHL1 KBTBD2 KLHL5

3.82e-0361963IPR011705
DomainEF_HAND_1

GNPTAB EFCAB13 ACTN4 ACTN1 P4HTM

4.05e-03204965PS00018
DomainBTB

KLHL1 KBTBD2 ZBTB45 KLHL5

4.67e-03131964PF00651
PathwayREACTOME_NEPHRIN_FAMILY_INTERACTIONS

ACTN4 ACTN1 ACTN2 ACTN3

6.39e-0623764M913
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

ACTN4 ACTN1 ACTN2 ACTN3 ITGAX ARAF TIAM1 VAV3

1.86e-05213768M18306
PathwayBIOCARTA_CELL2CELL_PATHWAY

ACTN1 ACTN2 ACTN3

3.20e-0512763M12851
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

ACTN4 ACTN1 ACTN2 ACTN3 RYR2

4.80e-0574765M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

ACTN4 ACTN1 ACTN2 ACTN3 RYR2

4.80e-0574765M39462
PathwayBIOCARTA_UCALPAIN_PATHWAY

ACTN1 ACTN2 ACTN3

5.25e-0514763M13143
PathwayKEGG_FOCAL_ADHESION

AKT3 ACTN4 ACTN1 ACTN2 ACTN3 VAV3 VEGFA

9.65e-05199767M7253
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

AKT3 ACTN1 ITGAX ARAF VAV3

2.21e-04102765MM15830
Pubmed

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.

ACTN4 ACTN1 ACTN2 ACTN3

5.68e-1149741629252
Pubmed

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

ACTN4 ACTN1 ACTN2 ACTN3

5.68e-11497416807302
Pubmed

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

ACTN4 ACTN1 ACTN2 ACTN3

2.84e-10597415841212
Pubmed

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.

ACTN4 ACTN1 ACTN2 ACTN3

2.84e-10597412837758
Pubmed

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.

ACTN4 ACTN1 ACTN2 ACTN3

2.84e-10597419943616
Pubmed

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

ACTN4 ACTN1 ACTN2 ACTN3

8.49e-10697418425115
Pubmed

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.

ACTN4 ACTN1 ACTN2 ACTN3

8.49e-10697422693585
Pubmed

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.

ACTN4 ACTN1 ACTN2 ACTN3

3.95e-09897420215401
Pubmed

Mice deficient in alpha-actinin-4 have severe glomerular disease.

ACTN4 ACTN1 ACTN2 ACTN3

3.95e-09897412782671
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

ACTN4 ACTN1 ACTN2 ACTN3

1.18e-081097420368620
Pubmed

The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.

ACTN4 ACTN2 ACTN3

2.10e-08397310656685
Pubmed

α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.

ACTN4 ACTN1 ACTN3

2.10e-08397321784188
Pubmed

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.

ACTN4 ACTN2 ACTN3

2.10e-0839738104223
Pubmed

Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.

ACTN4 ACTN1 ACTN2 ACTN3

2.77e-081297415465019
Pubmed

Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.

ACTN4 ACTN1 ACTN2 ACTN3

7.58e-081597411440986
Pubmed

Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.

ACTN4 ACTN1 ACTN2

7.30e-07797311724819
Pubmed

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.

ACTN4 ACTN1 ACTN2 ACTN3

9.50e-072797436899856
Pubmed

The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.

CLTCL1 ACTN2 ACTN3

1.17e-06897318687124
Pubmed

Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism.

BCO1 NF1 VEGFA

1.75e-06997322911456
Pubmed

Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

ACTN1 ACTN2 ACTN3

1.75e-06997311114196
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

VPS54 TFAM USP20 NF1 USP4 USP35

3.71e-0614797629576527
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

DCAF1 POLH DENND3 BCO1 FAT2 DNAH11

4.49e-0615297634299191
Pubmed

An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.

ACTN4 ACTN1

7.70e-06297223557398
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

7.70e-06297217259277
Pubmed

Critical role of CDK11(p58) in human breast cancer growth and angiogenesis.

CDK11B VEGFA

7.70e-06297226470709
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

7.70e-06297214722100
Pubmed

Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.

ACTN2 ACTN3

7.70e-06297219150855
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

7.70e-06297226009179
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

7.70e-06297232899693
Pubmed

A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.

FMNL2 FMNL3

7.70e-06297231751425
Pubmed

α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms.

ACTN2 ACTN3

7.70e-06297222253474
Pubmed

alpha-actinin-3 and performance.

ACTN2 ACTN3

7.70e-06297219696509
Pubmed

Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.

ACTN4 ACTN1

7.70e-06297220156433
Pubmed

Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.

ACTN1 ACTN2

7.70e-06297223664615
Pubmed

Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.

ACTN2 ACTN3

7.70e-06297232451822
Pubmed

Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11.

ACTN2 ACTN3

7.70e-0629721339456
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

7.70e-06297215033925
Pubmed

Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.

ACTN4 ACTN1

7.70e-06297234010028
Pubmed

Upregulation of VEGF-A without angiogenesis in a mouse model of dilated cardiomyopathy caused by mitochondrial dysfunction.

TFAM VEGFA

7.70e-06297212070272
Pubmed

Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo.

ACTN2 ACTN3

7.70e-0629729675099
Pubmed

ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.

ARAF NF1

7.70e-06297235613620
Pubmed

Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.

ACTN4 ACTN1

7.70e-06297220037648
Pubmed

HAMLET binding to α-actinin facilitates tumor cell detachment.

ACTN4 ACTN1

7.70e-06297221408150
Pubmed

FMNL formins boost lamellipodial force generation.

FMNL2 FMNL3

7.70e-06297228327544
Pubmed

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.

ACTN4 ACTN1

7.70e-06297228797528
Pubmed

α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.

ACTN4 ACTN1

7.70e-06297223454549
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

7.70e-06297230542613
Pubmed

Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.

FMNL2 FMNL3

7.70e-06297222790947
Pubmed

Increased synthesis of vascular endothelial growth factor in allergic airway inflammation in histidine decarboxylase knockout (HDC(-/-)) mice.

HDC VEGFA

7.70e-06297220715981
Pubmed

Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation.

ADGRE2 ITGAX

7.70e-06297226153037
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

7.70e-06297215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

7.70e-06297211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

7.70e-06297211673462
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

7.70e-06297225370123
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

7.70e-06297218618700
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GNPTAB ACTN4 VPS54 ACTN1 DZIP1 FMNL2 HNRNPF MIPOL1 WDR3 P4HTM TIAM1 DNAI7 WDR17 ZMYM5

1.32e-051285971435914814
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAF1 BBS2 ACTN4 ACTN1 FMNL2 DIS3 ARAF MIPOL1 NF1 TIAM1 TTI1 COL14A1 TRAPPC2L WDR62

1.79e-051321971427173435
Pubmed

MiR-20b targets AKT3 and modulates vascular endothelial growth factor-mediated changes in diabetic retinopathy.

AKT3 VEGFA

2.31e-05397227421659
Pubmed

Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes.

ACTN1 ACTN2

2.31e-05397230768638
Pubmed

C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.

APOB NF1

2.31e-05397211727199
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2

2.31e-05397218403125
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2

2.31e-0539727876312
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

2.31e-05397224123915
Pubmed

Increase levels of apo-A1 and apo B are associated in knee osteoarthritis: lack of association with VEGF-460 T/C and +405 C/G polymorphisms.

APOB VEGFA

2.31e-05397218597093
Pubmed

Colocalization of α-actinin and synaptopodin in the pyramidal cell axon initial segment.

ACTN4 ACTN2

2.31e-05397221940706
Pubmed

Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.

RYR1 RYR2

2.31e-05397223278119
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2

2.31e-05397222948152
Pubmed

The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism.

ACTN1 ACTN2

2.31e-05397211101506
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2

2.31e-05397210788707
Pubmed

Interaction of PKN with alpha-actinin.

ACTN1 ACTN2

2.31e-0539729030526
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2

2.31e-0539727621815
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2

2.31e-05397210473538
Pubmed

Direct binding of alpha-actinin enhances TRPP3 channel activity.

ACTN1 ACTN2

2.31e-05397217944866
Pubmed

Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.

ACTN4 ACTN1

2.31e-05397216751418
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2

2.31e-05397218434746
Pubmed

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

FMNL2 FMNL3

2.31e-05397212684686
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2

2.31e-0539729204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2

2.31e-05397221881589
Pubmed

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.

ACTN4 ACTN1

2.31e-05397223890175
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2

2.31e-05397212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2

2.31e-0539729242641
Pubmed

Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.

RYR1 RYR2

2.31e-05397223454728
Pubmed

Detecting Low-Variant Allele Frequency Mosaic Pathogenic Variants of NF1, TSC2, and AKT3 Genes from Blood in Patients with Neurodevelopmental Disorders.

AKT3 NF1

2.31e-05397237088138
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2

2.31e-05397225239916
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2

2.31e-05397218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2

2.31e-05397211159936
Pubmed

Intracellular calcium release channel expression during embryogenesis.

RYR1 RYR2

2.31e-0539729986730
Pubmed

Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.

DNAH14 DNAH6

2.31e-05397229323929
Pubmed

Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.

ACTN4 ACTN1

2.31e-05397216951376
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2

2.31e-0539727959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2

2.31e-0539724600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2

2.31e-0539727635066
Pubmed

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.

FMNL2 FMNL3

2.31e-05397228852060
Pubmed

Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.

RYR1 RYR2

4.60e-05497223992453
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2

4.60e-05497223413940
Pubmed

Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.

ACTN4 ACTN1

4.60e-05497222351778
Pubmed

CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.

ACTN4 ACTN1

4.60e-05497210753915
Pubmed

Titin mutations as the molecular basis for dilated cardiomyopathy.

ACTN1 ACTN2

4.60e-05497211846417
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2

4.60e-0549729607712
Pubmed

Interactions of a hemidesmosome component and actinin family members.

ACTN4 ACTN1

4.60e-05497211739652
InteractionMYOZ2 interactions

ACTN4 ACTN1 ACTN2 ACTN3

3.45e-0622974int:MYOZ2
InteractionADORA2A interactions

ACTN4 ACTN1 ACTN2 ACTN3

8.13e-0627974int:ADORA2A
InteractionSYNPO2L interactions

ACTN1 ACTN2 ACTN3

1.73e-0511973int:SYNPO2L
GeneFamilyActinins

ACTN4 ACTN1 ACTN2 ACTN3

2.45e-1047341112
GeneFamilyDyneins, axonemal

DNAH14 DNAH6 DNAH11

4.12e-0517733536
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

4.81e-053732287
GeneFamilyWD repeat domain containing

WDFY4 DENND3 WDR3 ERCC8 WDR17 WDR62

6.61e-04262736362
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT3 AFAP1L1 GRK3 TIAM1 VAV3

1.47e-03206735682
GeneFamilyUbiquitin specific peptidases

USP20 USP4 USP35

1.50e-0356733366
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL1 KBTBD2 ZBTB45 KLHL5

2.11e-03134734861
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF136 ZNF215 ZNF112 ZBTB45 ZNF20 ZNF32 ZNF432 PRDM14 ZNF548

2.34e-0371873928
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTLL9 RABL2B CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

1.44e-07181977dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

TTLL9 ZNF432 DNAI7 DNAH6 CFAP46 DNAH11

1.67e-06165976731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL9 CFAP119 DNAI7 DNAH6 CFAP46 HDC

1.85e-06168976fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL9 CFAP119 DNAI7 DNAH6 CFAP46 HDC

1.85e-061689767edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 CFAP119 WDR17 DNAH6 CFAP46 DNAH11

1.91e-06169976fba841664939c771881ba97f14ef1df6635c04ff
ToppCellfacs-GAT-Fat-18m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 ITGAX WDFY4 RYR1 GRK3 VAV3

1.91e-061699767a7416fcbffcf57d19b477d9da091e04e3499524
ToppCellfacs-GAT-Fat-18m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 ITGAX WDFY4 RYR1 GRK3 VAV3

1.91e-061699760e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCellfacs-GAT-Fat-18m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 ITGAX WDFY4 RYR1 GRK3 VAV3

1.91e-061699769bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

ADGRE2 ITGAX WDFY4 FMNL3 CHST15 VAV3

3.88e-06191976cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

ITGAX WDFY4 FMNL3 GRK3 TIAM1 VAV3

4.00e-06192976733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX WDFY4 FMNL3 GRK3 TIAM1

4.12e-061939763e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

4.24e-061949764a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF136 AKT3 CCDC178 KLHL5 TIAM1 TMLHE

4.37e-061959766a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

ADGRE2 ITGAX FMNL2 WDFY4 GRK3 VAV3

4.37e-06195976148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

4.37e-0619597679dc031258579ea328181dda33710dd897f1064a
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RABL2B CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

4.37e-061959763486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

ACTN1 ITGAX FMNL2 WDFY4 GRK3 VAV3

4.37e-0619597655e25f702af19146a161861cfd15f40bbda1dc35
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRE2 ITGAX FMNL2 WDFY4 GRK3 VAV3

4.50e-061969767026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RABL2B CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

4.50e-06196976d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX WDFY4 RYR1 GRK3 CHST15

4.63e-061979768af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TTLL9 CFAP119 DNAI7 DNAH6 WDR62 DNAH11

4.63e-06197976861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

ADGRE2 ITGAX FMNL2 WDFY4 GRK3 VAV3

4.63e-061979763896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TTLL9 DNAI7 DNAH6 WDR62 CFAP46 DNAH11

4.77e-06198976f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

ADGRE2 ITGAX WDFY4 GRK3 TIAM1 VAV3

4.77e-061989769bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellfacs-Lung-18m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACTN4 ADGRE2 HNRNPF AFAP1L1 KLHL5 VEGFA

4.91e-06199976c11e0044d3cc37f6bb26df033ad4448b419addfc
ToppCellCOVID-19_Mild-NK|COVID-19_Mild / Disease condition and Cell class

GNPTAB ACTN4 ITGAX DENND3 PYHIN1 VAV3

5.05e-06200976b586b0f1127293c2f8529be16b24229359041da2
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP119 DNAH6 WDR62 CFAP46 DNAH11

2.41e-05157975410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAX WDFY4 RYR1 DNAH6 WDR62

2.81e-051629757f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GNPTAB ADGRE2 POTEC TIAM1 HDC

2.98e-051649752c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

ACTN2 WDFY4 RYR2 GRK3 VAV3

3.53e-051709754232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLR1A ITGAX FMNL2 WDFY4 RYR1

3.74e-05172975a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACTN1 ACTN2 RYR2 COL14A1 PLCB4

3.84e-05173975cb6389536195443633adb06e5f1b7483530773d1
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF112 WDR3 ZBTB45 RABL2B IL17RE

4.17e-051769751510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

4.40e-05178975de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 CFAP119 DNAH6 CFAP46 DNAH11

4.40e-051789753b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACTN2 RYR2 GRK3 TIAM1 COL14A1

4.64e-0518097508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 ITGAX WDFY4 RYR1 FAT2

4.64e-051809756ac62bf1251978c8c12e715f7b73144fca619794
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

4.89e-051829757ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

4.89e-05182975fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.15e-051849755daff849625f2f41d56615569c0ed59cd733b34c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKT3 EXPH5 RYR2 TIAM1 PLCB4

5.28e-05185975cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 WDFY4 RYR2 FAT2 PLCB4

5.28e-05185975c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.28e-0518597530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.28e-051859753e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.28e-0518597518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.42e-05186975f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

5.56e-051879752b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EFCAB13 ADGRE2 RIOX2 TTI1 ZNF548

5.56e-05187975c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.56e-051879759e10ed56090d82589bc457788282f664b70ace4b
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CLTCL1 ACTN4 ACTN1 ACTN2 RYR2

5.70e-051889756d249fe92d51a19da19ec14bb2262d394255d577
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.70e-0518897561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

EXPH5 ZNF112 DENND3 IL17RE VEGFA

5.70e-0518897513f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.70e-0518897534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.70e-051889752b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

GNPTAB ITGAX HNRNPF PYHIN1 FMNL3

5.85e-05189975160963355256f7c0f2138da80c90de478f5a9fe8
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.85e-05189975a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.85e-0518997568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.85e-05189975b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

5.85e-0518997527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

5.85e-051899753e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

WDFY4 RYR1 GRK3 CHST15 VAV3

5.85e-051899752586f4088721c5debec86c2b211b739fd33713eb
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

5.99e-051909759ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

5.99e-05190975833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

6.15e-05191975e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

6.15e-051919759d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

ITGAX FMNL2 WDFY4 GRK3 TIAM1

6.15e-05191975dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX GRK3 TIAM1 CHST15

6.15e-0519197547a2afc4102199b4bc76bd01b2967c8016186462
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

6.15e-051919751c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGAX FMNL2 WDFY4 GRK3 TIAM1

6.30e-05192975bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.30e-05192975be592e661367affced9ebe80849b466e6adb3a34
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 DENND3 AFAP1L1 KLHL5 VEGFA

6.30e-051929754bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRE2 RYR2 TIAM1 COL14A1 VEGFA

6.30e-05192975ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellMonocytes-Inflammatory_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.30e-051929754be5c2c946337cd3e710137726358adca563f146
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

TTLL9 DNAI7 DNAH6 CFAP46 DNAH11

6.30e-05192975354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.30e-051929757bcdbd97fa8c3bfccde426d44979601226913fc3
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GNPTAB ACTN4 ITGAX PYHIN1 VAV3

6.46e-0519397554604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 RABL2B DNAH6 CFAP46 DNAH11

6.46e-05193975ea345d34440b25f65358a53dc72831998d1c3620
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFAP1L1 CHST15 VAV3 PLCB4 FAM135A

6.46e-05193975e1d546165dcc2392f540162206852c4717d7306f
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.46e-05193975ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.46e-051939750b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX WDFY4 RYR1 GRK3

6.46e-05193975f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

ITGAX WDFY4 GRK3 CHST15 VAV3

6.61e-05194975f09675cd472200363c458952f00d2e41990800ee
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.61e-051949751b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.61e-05194975b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.61e-051949757a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACTN1 ADGRE2 ITGAX DENND3 CHST15

6.61e-05194975ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX WDFY4 GRK3 TIAM1

6.61e-05194975badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

PLCB4 DNAI7 DNAH6 CFAP46 DNAH11

6.78e-05195975fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.78e-05195975157f1f9b0521c9eba11806eb4b6802ff116ab912
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

ITGAX FMNL2 WDFY4 GRK3 VAV3

6.78e-05195975c172c5599379c29123340621a36bfb1fc90c2115
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

PLCB4 DNAI7 DNAH6 CFAP46 DNAH11

6.78e-0519597521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAX WDFY4 RYR1 GRK3 CHST15

6.78e-05195975247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell18-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

6.78e-051959753441381759cd00d125752401dc99b78be1c78f88
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

PLCB4 DNAI7 DNAH6 CFAP46 DNAH11

6.78e-05195975eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.78e-05195975e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP119 DNAI7 DNAH6 CFAP46 DNAH11

6.78e-051959756365e3893e38231090ec2dbef010dec71dea3d07
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 ITGAX WDFY4 RYR1 GRK3

6.78e-0519597509df40ff9b493170861b3f6e57a942a834655b5c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.78e-0519597595327f2818bcdca53dbd2971f674a9042a1392c6
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

RABL2B DNAI7 DNAH6 CFAP46 DNAH11

6.94e-05196975de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

ADGRE2 ITGAX FMNL2 GRK3 CHST15

6.94e-05196975256c557fa11414c9d2cbb1fcff33f482ee1c78ac
Drugconen

SEPTIN4 ACTN4 ACTN1 ACTN2

4.08e-0715974CID000093117
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN4 ACTN1 ACTN2 ACTN3

4.22e-105914DOID:0111128 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

2.82e-053912DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

2.82e-053912DOID:8545 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis type 1 (implicated_via_orthology)

VPS54 VEGFA

5.62e-054912DOID:0060193 (implicated_via_orthology)
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

ACTN2 RYR2

4.17e-0410912DOID:0050431 (is_implicated_in)
Diseasefree cholesterol in small LDL measurement

EFCAB13 APOB ZNF112

5.95e-0453913EFO_0022271
DiseaseMalformations of Cortical Development

AKT3 WDR62

8.36e-0414912C1955869
DiseaseCortical Dysplasia

AKT3 WDR62

8.36e-0414912C0431380
Diseaselow density lipoprotein cholesterol measurement, physical activity

N4BP2L1 APOB DNAH11

1.13e-0366913EFO_0003940, EFO_0004611
Diseasealpha-L-iduronidase measurement

GAK GNPTAB

1.24e-0317912EFO_0020139
DiseaseTachycardia

RYR2 VAV3

1.39e-0318912C0039231
DiseaseTachyarrhythmia

RYR2 VAV3

1.39e-0318912C0080203
Diseaselung non-small cell carcinoma (is_marker_for)

AKT3 NF1 PRDM14 VEGFA

1.88e-03169914DOID:3908 (is_marker_for)
Diseasemalignant astrocytoma (is_marker_for)

AKT3 NF1

2.28e-0323912DOID:3069 (is_marker_for)
DiseaseCoronary heart disease

APOB DNAH11

2.48e-0324912C0010068
DiseaseDyslipidemias

APOB DNAH11

2.48e-0324912C0242339
DiseaseDyslipoproteinemias

APOB DNAH11

2.48e-0324912C0598784
Diseaseuric acid measurement

POLR1A EFCAB13 TFAM BRAP MIPOL1 KLHL5 VEGFA

2.82e-03610917EFO_0004761
Diseaseresponse to perphenazine

FMNL3 FRA10AC1

2.91e-0326912GO_0097334

Protein segments in the cluster

PeptideGeneStartEntry
YKHFEETQHTYAMQL

BRAP

346

Q7Z569
YHLSQHGVFSEKEMR

GRK3

281

P35626
FDNKHTNYTMEHIRV

ACTN1

701

P12814
LVFDNKHTNYTMEHI

ACTN2

706

P35609
HLSSFAVLMAHYDVQ

ADGRE2

516

Q9UHX3
DNKHTNYTMEHIRVG

ACTN4

721

O43707
HYNHQRFPSISEEKM

CFAP46

276

Q8IYW2
HYSTLVHMFNTELDV

DNAH11

591

Q96DT5
VSAHHRTMREDYSDK

CDK11B

211

P21127
ESKCVQAYHAHFVSM

DENND3

526

A2RUS2
AHKDLDRVMDYHFTT

BCKDK

321

O14874
DDHYVMQEHRKVPFA

TNK2

281

Q07912
STTHHKRKTMNDFDY

AKT3

136

Q9Y243
DFHKYMRSHKAESSE

P4HTM

256

Q9NXG6
SESEEKESHVAMHRY

ITGAX

941

P20702
YHKAHACIMVFDVQR

RABL2B

91

Q9UNT1
AHVRHGTEMAKYFES

HDC

376

P19113
VSMSRLHFYDSNVIH

OR8H2

161

Q8N162
DMKHSFTEDHYVEFS

DCAF1

1171

Q9Y4B6
SFHKVRHSEDMQFAF

GNPTAB

981

Q3T906
VYCTTEKYNVMEHRH

MIPOL1

76

Q8TD10
VHFTDYSQHTQMVMA

IL17RE

276

Q8NFR9
FKREHAQTVFDHYMQ

CCDC178

701

Q5BJE1
FHLIAMDAYQRHTKF

FRA10AC1

66

Q70Z53
HVNVMFDYFHLSVVS

FAM135A

151

Q9P2D6
TTTKLMDFHDRAHYQ

FAT2

416

Q9NYQ8
DHESTKLYQIDVMAH

FAT2

2756

Q9NYQ8
VEHKFTAVYHQDAFM

KBTBD2

156

Q8IY47
TAVYHQDAFMQLSHD

KBTBD2

161

Q8IY47
TERHKKHYNETSNMS

EXPH5

256

Q8NEV8
AHNYTMEHFMEVIRN

KLHL5

341

Q96PQ7
YMENHSIEGVRHVFS

PRPF39

396

Q86UA1
DVFNFEETVYSHHMS

ERCC8

136

Q13216
KFNTSEEHHADMYRS

THAP12

616

O43422
YLDVHSMHQLEKTTN

CFAP119

81

A1A4V9
HDTQYTVFHSLIRAM

GAK

281

O14976
YHHLHVADTRFDMVQ

ARAF

391

P10398
DHFSLRARYHMKADS

APOB

1381

P04114
EDKHYFHVILTEMAN

DNAH6

2341

Q9C0G6
DEYHSVHQKLSADMA

BBS2

601

Q9BXC9
STHVYNVAEFDLMHT

COL14A1

311

Q05707
VHSVEDMNFRVHLQY

FMNL3

331

Q8IVF7
VAMHVAYYRHETTRK

GJB6

91

O95452
FKYESSENEQRRMFH

PYHIN1

226

Q6K0P9
EFHSTLYHMVKDFAS

DNAI7

671

Q6TDU7
TEYFVRCIKHMFTNH

COPG2

641

Q9UBF2
DLTKREYTMHDHNTL

FMNL2

911

Q96PY5
EFLTMSQLYSVAKHH

DNAH14

781

Q0VDD8
VTKHTYIDSNHMVDI

EFCAB13

261

Q8IY85
YHQHDMSFDLSKVRV

RYR1

1456

P21817
AMESHKHYTQSETEF

RYR2

4051

Q92736
HYAASKNRHEIAVML

PSMD10

111

O75832
TTLHYAVHNEDKLMA

POTEC

241

B2RU33
FTTYKLMHTHQTVDF

MIOX

41

Q9UGB7
ESMGHRYIEVFKSHR

HNRNPF

76

P52597
PTENELKFHYMVHTS

TRAPPC2L

21

Q9UL33
ASNYEVIMKSQHLHE

POLR1A

1041

O95602
HVAEERNIHYNMSSF

PLCB4

581

Q15147
HMQDLKDVTRETHYE

SEPTIN4

391

O43236
SDQETFYSHMKFHED

PRDM14

556

Q9GZV8
LDHRYNEFKLHAIMS

WDR17

66

Q8IZU2
ALTRYDAHKMSHDAF

POLH

386

Q9Y253
IQHAKEDETRYHNEM

TFAM

201

Q00059
HKMAQYAQRASVAFH

DIS3

821

Q9Y2L1
HHASAVRFSKEYEMQ

DZIP1

261

Q86YF9
QTKFYTDAMVVFHHV

BCO1

296

Q9HAY6
TDAMVVFHHVNAYEE

BCO1

301

Q9HAY6
DNKHTVYSMEHIRVG

ACTN3

716

Q08043
YFHKDHMDLRTHVNA

AFAP1L1

446

Q8TED9
AHLRSHMAEESKNEY

TRIP10

176

Q15642
DHLYKDAMQHAAESR

CLTCL1

1531

P53675
LRLEDHASNVKYTMH

CHST15

476

Q7LFX5
DATRYMDGHHVKDIS

TIMM50

221

Q3ZCQ8
VFISFSSIQYHKMTH

ZNF20

291

P17024
ENMVVADVYNHRFHK

USP4

531

Q13107
ADVYNHRFHKIFQMD

USP4

536

Q13107
TFSSRKNYTKHMFIH

ZBTB45

411

Q96K62
AFSYLNSFRTHEMIH

ZNF136

456

P52737
SEEHYHLDVAIKTMN

TIAM1

1211

Q13009
KYMLLTFQHSHEAFH

USP35

331

Q9P2H5
TDDHTMYAAVKVLHS

WDFY4

1386

Q6ZS81
SSKFEEFMTRHQVHE

NF1

1566

P21359
VYIYHSLKNSRETHM

RIOX2

391

Q8IUF8
HEVMYSFKINSHVSF

USP20

591

Q9Y2K6
RTHHVAEKTTLYDMD

WDR62

621

O43379
EMSYRHNIYEKAFSH

ZNF112

356

Q9UJU3
NFDHTYMDEHVRISH

TTLL9

86

Q3SXZ7
KHEESEMHVNNSVKY

ZMYM5

621

Q9UJ78
RMLKSVEQYHEHNAF

ZNF432

96

O94892
DIRHQKSHTTMNSYE

ZNF215

366

Q9UL58
YSANFMKHQTVHTSE

ZNF548

236

Q8NEK5
YSTEAVQAHMNDKSH

ZNF622

316

Q969S3
HKSLFAHDDSVMYLQ

WDR3

626

Q9UNX4
NHHEVVKFMDVYQRS

VEGFA

36

P15692
HEDHFELKYANTVMR

TMLHE

56

Q9NVH6
AFFNVMTEAHHKYDH

ZNF32

21

P17041
DHFMELYHQSVVYRK

TTI1

506

O43156
QYSMLRHFDHITKDY

VPS54

836

Q9P1Q0
SNFHDFKMHTFTRVT

VAV3

511

Q9UKW4
AVHHAEQTFRKMESY

KLHL1

191

Q9NR64
RMKERYEHDVTFHSV

N4BP2L1

171

Q5TBK1