Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS6 PCSK2 HGF

5.12e-0443083GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS6 PCSK2 HGF

1.73e-0365483GO:0008233
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PCSK2 HGF

2.43e-0319082GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK2 HGF

2.87e-0320782GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK2 HGF

3.01e-0321282GO:0017171
MousePhenosternebra fusion

ADAMTS6 KMT2A

1.75e-051952MP:0010082
MousePhenoabnormal sternebra morphology

ADAMTS6 KMT2A

1.35e-045252MP:0004322
MousePhenoliver hypoplasia

KMT2A HGF

1.92e-046252MP:0000600
MousePhenoabnormal liver size

LETMD1 KMT2A HGF

6.08e-0456253MP:0004848
MousePhenoshort snout

ADAMTS6 KMT2A

9.22e-0413652MP:0000445
MousePhenosmall snout

ADAMTS6 KMT2A

1.03e-0314452MP:0030190
MousePhenoabnormal placenta vasculature

ADAMTS6 HGF

1.83e-0319252MP:0003231
MousePhenoincreased malignant tumor incidence

PCSK2 KMT2A

2.77e-0323752MP:0002018
MousePhenoenlarged liver

LETMD1 KMT2A

3.15e-0325352MP:0000599
MousePhenoabnormal sternum morphology

ADAMTS6 KMT2A

3.20e-0325552MP:0000157
MousePhenoabnormal snout morphology

ADAMTS6 KMT2A

3.25e-0325752MP:0000443
MousePhenolethality throughout fetal growth and development, complete penetrance

KMT2A HGF

3.40e-0326352MP:0011099
MousePhenoreduced female fertility

PCSK2 KMT2A

4.28e-0329652MP:0001923
MousePhenoabnormal pectoral girdle bone morphology

ADAMTS6 KMT2A

4.43e-0330152MP:0004508
MousePhenosmall liver

KMT2A HGF

4.84e-0331552MP:0000601
Pubmed

HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.

KMT2A HGF

1.30e-0688223934123
Pubmed

The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.

PCSK2 HGF

4.36e-05448223070814
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Rgs14_(CA2_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

HGF HHIPL2

6.08e-056782771fc7c4917b5dc5ebf1b7be304d62902f0b75cc
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Rgs14_(CA2_Principal_cells)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

HGF HHIPL2

6.08e-056782f56d8787ab2170997d28a2f66d83b4c18362b97d
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Muscle_invasive_urothelial_carcinoma-6|TCGA-Bladder / Sample_Type by Project: Shred V9

HGF HHIPL2

1.28e-049782833f2e02ae10d4b021404bd893c06ef308ca5a7a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCSK2 KMT2A

3.01e-041498254c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCSK2 KMT2A

3.01e-041498214d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.05e-04150828645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

ADAMTS6 DRP2

3.30e-041568245a05c7a45a3ec8551818ab67f18b3b9553934c1
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 HGF

3.34e-04157828a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 HGF

3.34e-0415782f896997490bb2eec598c6581f161220e70f9a991
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 HGF

3.34e-04157822ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 HGF

3.34e-04157828d30d8e6fae93afcada6bd68799439335cd65b69
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC9A7 HGF

3.34e-041578214a8516346a89a89f1119b744625bd9844a74a03
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC9A7 PCSK2

3.43e-0415982807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

LETMD1 SLC9A7

3.51e-04161825f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.56e-0416282f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.56e-0416282c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.56e-04162825d902bb31e691aea9749617cc88303c2448f24b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.64e-041648243630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.64e-041648246208f18325976c89f572f6627aea0582142b92d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.64e-0416482108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SLC9A7 DRP2

3.78e-0416782e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

SLC9A7 ADAMTS6

3.82e-0416882a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC9A7 PCSK2

3.87e-0416982d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.92e-041708299dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.92e-04170823a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

3.92e-04170826af7dee9b8298d4499e05a82cf9cdfe3bd81d384
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 PCSK2

3.92e-0417082cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC9A7 PCSK2

4.05e-041738223e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

4.10e-04174820df738309b7b6e77675ea74e7a87e66601b0073d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

4.20e-0417682e788c7e0b2bfde31fddbf9e04d07140f8b964857
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

4.24e-041778264fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC9A7 PCSK2

4.24e-041778259726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 HHIPL2

4.24e-0417782cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

4.29e-0417882e4e11e4940c911c17806200c25096928153c684d
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

SLC9A7 HGF

4.29e-0417882ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC9A7 HHIPL2

4.29e-041788204bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF HHIPL2

4.29e-0417882a62137d7f5fac16619f8a02844cdb0be7a794bf2
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS6 KMT2A

4.29e-0417882f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 KMT2A

4.39e-0418082423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 KMT2A

4.39e-0418082dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC9A7 PCSK2

4.48e-0418282b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

ADAMTS6 DRP2

4.53e-041838206e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC9A7 PCSK2

4.53e-0418382f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS6 PCSK2

4.63e-041858216e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS6 KMT2A

4.63e-0418582f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS6 DRP2

4.68e-0418682bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS6 KMT2A

4.68e-0418682bbcd9062c0f6f65ca6f3cb101b6fa72ddd1e14fe
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK2 DRP2

4.78e-0418882bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 ADAMTS6

4.94e-0419182b7d17d3ba488378b30f3732f8109f4a7c1673e61
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCSK2 HGF

4.99e-0419282d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 ADAMTS6

4.99e-041928289b8ebdc285ed3c0f807fd1157271130d37dfa41
ToppCellCOVID-19_Mild-Lymphoid_B-B_intermediate|COVID-19_Mild / Disease group, lineage and cell class

SLC9A7 ADAMTS6

5.09e-0419482bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 KMT2A

5.14e-04195827796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 KMT2A

5.14e-04195823e519cffa6144a62b06124642a14c9ff39b76554
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK2 DRP2

5.20e-0419682b6226163d9fc93ecfff2115bb74408303a000490
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HGF DRP2

5.30e-0419882300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate|COVID-19_Mild / Disease, condition lineage and cell class

SLC9A7 ADAMTS6

5.36e-04199821c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCellsevere-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A7 ADAMTS6

5.36e-041998217283d75a2a900369f63ed02996e7ede97f46140
ToppCellSepsis-Int-URO-Lymphocyte-B-B_intermediate|Int-URO / Disease, condition lineage and cell class

SLC9A7 ADAMTS6

5.41e-0420082221dd8d8851c47f2202ba848de3a041b17b1db3f
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A7 ADAMTS6

5.41e-0420082fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellsevere-B_intermediate|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A7 ADAMTS6

5.41e-04200826d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCellmild-B_intermediate|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A7 ADAMTS6

5.41e-04200828e3132a1fe3708f725c5c4077878fb87bbea3678
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

ADAMTS6 PCSK2 KMT2A

3.25e-05193835437_UP
Drugrofecoxib; Up 200; 10uM; MCF7; HG-U133A

KMT2A HGF HHIPL2

3.46e-0519783205_UP
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; PC3; HT_HG-U133A

SLC9A7 PCSK2 HHIPL2

3.46e-05197833672_UP
DrugIndapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

ADAMTS6 HGF DRP2

3.51e-05198833778_UP
DrugLuteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A

SLC9A7 KMT2A HGF

3.57e-05199836658_UP
DrugAC1O745K

KMT2A HGF

1.31e-045082CID006518178
Drugchlorate

PCSK2 HGF

5.58e-0410382CID000019654
DrugReserpine

PCSK2 HGF

7.43e-0411982ctd:D012110
Drugkaempferol

KMT2A HGF

1.16e-0314982ctd:C006552
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

LETMD1 KMT2A

1.71e-03181821077_UP
DrugDicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

1.82e-03187824323_DN
Drugtroglitazone; Up 200; 10uM; PC3; HG-U133A

HHIPL2 DRP2

1.88e-0319082462_UP
DrugTiclopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; MCF7; HT_HG-U133A

KMT2A HHIPL2

1.88e-03190824155_UP
DrugSulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

1.88e-03190824322_DN
DrugProglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A

KMT2A HHIPL2

1.90e-03191823861_UP
DrugSolasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A

SLC9A7 KMT2A

1.90e-03191823830_UP
DrugEthynodiol diacetate [297-76-7]; Up 200; 10.4uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

1.94e-03193826678_UP
Drug15d-PGJ2; Up 200; 10uM; MCF7; HG-U133A

HGF DRP2

1.94e-0319382201_UP
DrugRemoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; HL60; HT_HG-U133A

KMT2A HGF

1.94e-03193823124_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A

KMT2A DRP2

1.94e-03193822209_UP
DrugFluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; PC3; HT_HG-U133A

HHIPL2 DRP2

1.94e-03193826757_UP
DrugAG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A

KMT2A HGF

1.94e-03193826400_DN
DrugMinocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A

SLC9A7 DRP2

1.96e-03194825077_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A

KMT2A HGF

1.96e-03194824441_UP
DrugDubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

KMT2A HGF

1.96e-03194825774_UP
DrugFluspirilen [1841-19-6]; Up 200; 8.4uM; PC3; HT_HG-U133A

SLC9A7 PCSK2

1.98e-03195826662_UP
DrugAmiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; PC3; HT_HG-U133A

HGF DRP2

1.98e-03195824657_UP
DrugProtriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; HL60; HT_HG-U133A

KMT2A HGF

1.98e-03195823119_DN
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

SLC9A7 HGF

1.98e-03195824300_UP
Druggenistein; Down 200; 1uM; MCF7; HG-U133A

KMT2A DRP2

1.98e-0319582268_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HG-U133A

HGF HHIPL2

1.98e-0319582489_DN
Drugcox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A

KMT2A HHIPL2

1.98e-0319582207_UP
DrugPalmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A

SLC9A7 HGF

1.98e-03195822795_UP
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; HL60; HG-U133A

KMT2A HGF

2.00e-03196821445_DN
DrugSulfamethoxazole [723-46-6]; Up 200; 15.8uM; HL60; HT_HG-U133A

KMT2A HGF

2.00e-03196822335_UP
DrugCrotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

PCSK2 DRP2

2.00e-03196825689_UP
DrugMethylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; HL60; HG-U133A

KMT2A HGF

2.00e-03196821567_DN
DrugEstrone [53-16-7]; Up 200; 14.8uM; PC3; HT_HG-U133A

KMT2A HGF

2.00e-03196826647_UP
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

2.00e-03196824291_UP
DrugDomperidone maleate; Down 200; 7.4uM; HL60; HT_HG-U133A

KMT2A HGF

2.00e-03196821301_DN
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

KMT2A HHIPL2

2.00e-03196825793_UP
DrugDibucaine [85-79-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A

HHIPL2 DRP2

2.00e-03196824149_UP
DrugBemegride [64-65-3]; Down 200; 25.8uM; MCF7; HT_HG-U133A

SLC9A7 HGF

2.00e-03196823389_DN
DrugSulindac [38194-50-2]; Down 200; 11.2uM; HL60; HT_HG-U133A

KMT2A HGF

2.00e-03196821857_DN
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; PC3; HT_HG-U133A

KMT2A DRP2

2.00e-03196823994_UP
DrugAmyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

KMT2A DRP2

2.00e-03196824169_UP
DrugIodixanol [92339-11-2]; Up 200; 2.6uM; MCF7; HT_HG-U133A

SLC9A7 HGF

2.02e-03197823362_UP
DrugGuanadrel sulfate [22195-34-2]; Up 200; 7.6uM; PC3; HT_HG-U133A

SLC9A7 HHIPL2

2.02e-03197823698_UP
DrugRiluzole hydrochloride; Up 200; 14.8uM; PC3; HT_HG-U133A

SLC9A7 PCSK2

2.02e-03197823666_UP
DrugCefaclor [70356-03-5]; Up 200; 10.4uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

2.02e-03197826622_UP
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SLC9A7 DRP2

2.02e-03197823978_UP
DrugTriamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A

KMT2A HGF

2.02e-03197822241_UP
DrugDebrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

2.02e-03197826688_UP
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; PC3; HT_HG-U133A

ADAMTS6 PCSK2

2.02e-03197825773_UP
Drug17-AAG; Down 200; 1uM; MCF7; HG-U133A

ADAMTS6 DRP2

2.02e-0319782381_DN
DrugPenbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A

KMT2A DRP2

2.02e-03197827476_UP
DrugCarisoprodol [78-44-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

KMT2A HGF

2.02e-03197821314_DN
DrugBenperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

SLC9A7 KMT2A

2.02e-03197822836_UP
DrugIsometheptene mucate; Up 200; 8.2uM; PC3; HT_HG-U133A

SLC9A7 HGF

2.02e-03197825082_UP
DrugS(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A

ADAMTS6 PCSK2

2.04e-03198825694_UP
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PCSK2 HHIPL2

2.04e-03198821529_UP
DrugICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A

SLC9A7 PCSK2

2.04e-03198824462_UP
DrugThalidomide [50-35-1]; Down 200; 15.4uM; HL60; HG-U133A

KMT2A HGF

2.04e-03198821411_DN
DrugCephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A

KMT2A HGF

2.04e-03198825615_UP
DrugHyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A

HGF HHIPL2

2.04e-03198822108_UP
DrugVitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A

SLC9A7 DRP2

2.04e-03198824413_UP
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

SLC9A7 KMT2A

2.04e-03198823793_DN
DrugNiridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A

KMT2A DRP2

2.04e-03198824621_UP
DrugPropranolol hydrochloride [318-98-9]; Up 200; 13.6uM; MCF7; HT_HG-U133A

SLC9A7 HGF

2.04e-03198823396_UP
Drugsodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A

KMT2A DRP2

2.06e-0319982408_UP
DrugNiacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A

SLC9A7 KMT2A

2.06e-03199823381_DN
DrugProglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A

SLC9A7 HHIPL2

2.06e-03199824337_UP
DrugS(+)-Terguride [37686-84-3]; Down 200; 11.8uM; HL60; HT_HG-U133A

KMT2A HGF

2.06e-03199823082_DN
DrugOfloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A

PCSK2 HGF

2.06e-03199822302_UP
Drugsulindac sulfone; Down 200; 50uM; MCF7; HG-U133A

PCSK2 KMT2A

2.06e-0319982314_DN
Drug3-aminobenzamide; Down 200; 10000uM; MCF7; HG-U133A

HGF DRP2

2.06e-0319982590_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; HL60; HG-U133A

KMT2A HGF

2.06e-03199822024_DN
DrugProparacaine hydrochloride [5875-06-9]; Up 200; 12uM; MCF7; HT_HG-U133A

SLC9A7 HGF

2.06e-03199825433_UP
DrugDorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; PC3; HT_HG-U133A

KMT2A HGF

2.06e-03199825785_UP
Drugretinoic acid; Down 200; 1uM; MCF7; HG-U133A

ADAMTS6 DRP2

2.06e-0319982384_DN
DrugFlunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A

KMT2A HGF

2.08e-03200826023_UP
Diseasemyocardial infarction (is_implicated_in)

PCSK2 HGF

3.08e-049982DOID:5844 (is_implicated_in)
DiseaseAcute Myeloid Leukemia, M1

KMT2A HGF

4.90e-0412582C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

KMT2A HGF

4.90e-0412582C1879321
DiseaseLeukemia, Myelocytic, Acute

KMT2A HGF

9.35e-0417382C0023467
Diseasecentral corneal thickness

ADAMTS6 KMT2A

2.94e-0330982EFO_0005213

Protein segments in the cluster

PeptideGeneStartEntry
FFKLSAYGKHFHLNL

ADAMTS6

86

Q9UKP5
AINGKYHRFLGRHFP

LETMD1

66

Q6P1Q0
HRHKFLPERYPDKGF

HGF

241

P14210
GAKHCRNYKFRFHKP

KMT2A

3736

Q03164
GLAFHPKFRHNRKFY

HHIPL2

276

Q6UWX4
KFRSKHYFSKHPQRG

DRP2

676

Q13474
IIFHAGYSLKKRHFF

SLC9A7

191

Q96T83
LYHFYHNGLAKAKRR

PCSK2

66

P16519