Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	2.81e-06	2	34	2	GO:0004339
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	2.81e-05	5	34	2	GO:0004558
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM MGAM2	5.88e-05	7	34	2	GO:0090599
GeneOntologyMolecularFunction	glucosidase activity	MGAM MGAM2	2.91e-04	15	34	2	GO:0015926
GeneOntologyMolecularFunction	I-SMAD binding	SMAD2 SMAD9	3.77e-04	17	34	2	GO:0070411
GeneOntologyMolecularFunction	exopeptidase activity	ACE NPEPL1 ATG4D	8.60e-04	110	34	3	GO:0008238
GeneOntologyMolecularFunction	mannosyltransferase activity	POMT1 PIGM	1.03e-03	28	34	2	GO:0000030
GeneOntologyCellularComponent	heteromeric SMAD protein complex	SMAD2 SMAD9	7.15e-05	8	34	2	GO:0071144
GeneOntologyCellularComponent	SMAD protein complex	SMAD2 SMAD9	1.15e-04	10	34	2	GO:0071141
Domain	NtCtMGAM_N	MGAM MGAM2	1.81e-05	4	33	2	PF16863
Domain	Gal_mutarotase_N	MGAM MGAM2	1.81e-05	4	33	2	IPR031727
Domain	Glyco_hydro_31_AS	MGAM MGAM2	4.52e-05	6	33	2	IPR030458
Domain	Glyco_hydro_31	MGAM MGAM2	6.32e-05	7	33	2	PF01055
Domain	Glyco_hydro_31	MGAM MGAM2	6.32e-05	7	33	2	IPR000322
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	6.32e-05	7	33	2	PS00129
Domain	Dwarfin	SMAD2 SMAD9	8.42e-05	8	33	2	IPR013790
Domain	Trefoil	MGAM MGAM2	8.42e-05	8	33	2	PF00088
Domain	DWB	SMAD2 SMAD9	8.42e-05	8	33	2	SM00524
Domain	-	SMAD2 SMAD9	8.42e-05	8	33	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD2 SMAD9	8.42e-05	8	33	2	IPR013019
Domain	MH2	SMAD2 SMAD9	8.42e-05	8	33	2	PS51076
Domain	MH1	SMAD2 SMAD9	8.42e-05	8	33	2	PS51075
Domain	MH2	SMAD2 SMAD9	8.42e-05	8	33	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD2 SMAD9	8.42e-05	8	33	2	IPR001132
Domain	P_TREFOIL_2	MGAM MGAM2	1.08e-04	9	33	2	PS51448
Domain	PD	MGAM MGAM2	1.08e-04	9	33	2	SM00018
Domain	-	MGAM MGAM2	1.65e-04	11	33	2	4.10.110.10
Domain	MAD_homology1_Dwarfin-type	SMAD2 SMAD9	1.98e-04	12	33	2	IPR003619
Domain	DWA	SMAD2 SMAD9	1.98e-04	12	33	2	SM00523
Domain	MH1	SMAD2 SMAD9	1.98e-04	12	33	2	PF03165
Domain	P_trefoil_dom	MGAM MGAM2	1.98e-04	12	33	2	IPR000519
Domain	SMAD_dom-like	SMAD2 SMAD9	3.58e-04	16	33	2	IPR017855
Domain	-	SMAD2 SMAD9	3.58e-04	16	33	2	2.60.200.10
Domain	Gal_mutarotase_SF_dom	MGAM MGAM2	4.05e-04	17	33	2	IPR011013
Domain	SMAD_FHA_domain	SMAD2 SMAD9	3.80e-03	52	33	2	IPR008984
Domain	Glycoside_hydrolase_SF	MGAM MGAM2	3.94e-03	53	33	2	IPR017853
Domain	TyrKc	FRK TIE1	1.05e-02	88	33	2	SM00219
Domain	Tyr_kinase_cat_dom	FRK TIE1	1.05e-02	88	33	2	IPR020635
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION_AMYLASE_	MGAM MGAM2	1.26e-04	9	27	2	M47622
Pubmed	Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study.	SMAD2 STAT6	9.28e-07	2	34	2	19032363
Pubmed	Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.	SMAD2 SMAD9	9.26e-06	5	34	2	25141865
Pubmed	Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.	SMAD2 SMAD9	1.39e-05	6	34	2	9256479
Pubmed	Smad7 is required for the development and function of the heart.	SMAD2 SMAD9	1.39e-05	6	34	2	18952608
Pubmed	Defective pulmonary vascular remodeling in Smad8 mutant mice.	SMAD2 SMAD9	1.39e-05	6	34	2	19419974
Pubmed	Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons.	SMAD2 SMAD9	1.39e-05	6	34	2	21518886
Pubmed	Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.	SMAD2 SMAD9	1.39e-05	6	34	2	11850197
Pubmed	Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.	SMAD2 SMAD9	1.94e-05	7	34	2	15009097
Pubmed	Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction.	SMAD2 SMAD9	1.94e-05	7	34	2	15376321
Pubmed	Negative regulation of BMP/Smad signaling by Tob in osteoblasts.	SMAD2 SMAD9	1.94e-05	7	34	2	11163184
Pubmed	A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension.	SMAD2 SMAD9	2.59e-05	8	34	2	19211612
Pubmed	Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.	SMAD2 SMAD9	2.59e-05	8	34	2	10647776
Pubmed	Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.	SMAD2 SMAD9	2.59e-05	8	34	2	23804438
Pubmed	TGF-beta signaling by Smad proteins.	SMAD2 SMAD9	2.59e-05	8	34	2	10708949
Pubmed	Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.	IL17RC STAT6	2.59e-05	8	34	2	28355561
Pubmed	Holding their own: the noncanonical roles of Smad proteins.	SMAD2 SMAD9	3.33e-05	9	34	2	19018011
Pubmed	GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.	SMAD2 SMAD9	3.33e-05	9	34	2	24932701
Pubmed	TGF-beta signal transduction.	SMAD2 SMAD9	3.33e-05	9	34	2	9759503
Pubmed	Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.	SMAD2 SMAD9	3.33e-05	9	34	2	30134160
Pubmed	Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5.	SMAD2 SMAD9	3.33e-05	9	34	2	15993878
Pubmed	Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.	SMAD2 SMAD9	3.33e-05	9	34	2	24816837
Pubmed	Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway.	SMAD2 SMAD9	3.33e-05	9	34	2	14729481
Pubmed	Prdm16 is required for normal palatogenesis in mice.	SMAD2 SMAD9	3.33e-05	9	34	2	20007998
Pubmed	Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.	SMAD2 SMAD9	3.33e-05	9	34	2	25155999
Pubmed	Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.	SMAD2 SMAD9	3.33e-05	9	34	2	26555259
Pubmed	The Smad pathway.	SMAD2 SMAD9	3.33e-05	9	34	2	10708948
Pubmed	Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.	SMAD2 SMAD9	3.33e-05	9	34	2	9389648
Pubmed	Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis.	SMAD2 SMAD9	4.15e-05	10	34	2	29986157
Pubmed	Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor.	SMAD2 SMAD9	4.15e-05	10	34	2	9436979
Pubmed	TGF-β signaling inhibits canonical BMP signaling pathway during palate development.	SMAD2 SMAD9	4.15e-05	10	34	2	29247325
Pubmed	Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.	SMAD2 SMAD9	4.15e-05	10	34	2	23620745
Pubmed	Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.	SMAD2 SMAD9	5.07e-05	11	34	2	27741240
Pubmed	Downregulation of bone morphogenetic protein receptor axis during HIV-1 and cocaine-mediated pulmonary smooth muscle hyperplasia: implications for HIV-related pulmonary arterial hypertension.	SMAD2 SMAD9	5.07e-05	11	34	2	24008158
Pubmed	Smad7-induced beta-catenin degradation alters epidermal appendage development.	SMAD2 SMAD9	5.07e-05	11	34	2	16950122
Pubmed	BMPR-II is dispensable for formation of the limb skeleton.	SMAD2 SMAD9	6.08e-05	12	34	2	21538804
Pubmed	Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.	SMAD2 SMAD9	6.08e-05	12	34	2	17460146
Pubmed	Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.	SMAD2 SMAD9	6.08e-05	12	34	2	15923624
Pubmed	Impaired Annulus Fibrosus Development and Vertebral Fusion Cause Severe Scoliosis in Mice with Deficiency of c-Jun NH2-Terminal Kinases 1 and 2.	SMAD2 SMAD9	6.08e-05	12	34	2	30664861
Pubmed	Smad expression during kidney development.	SMAD2 SMAD9	6.08e-05	12	34	2	14656760
Pubmed	Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.	SMAD2 SMAD9	7.19e-05	13	34	2	16959237
Pubmed	Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.	SMAD2 SMAD9	7.19e-05	13	34	2	18329379
Pubmed	Endoglin is required for myogenic differentiation potential of neural crest stem cells.	SMAD2 SMAD9	7.19e-05	13	34	2	17628518
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	C15orf39 AZIN2 STAT6 TECPR1	7.77e-05	233	34	4	37704626
Pubmed	Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis.	SMAD2 SMAD9	8.38e-05	14	34	2	23238123
Pubmed	Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development.	SMAD2 SMAD9	8.38e-05	14	34	2	17670744
Pubmed	The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.	SMAD2 SMAD9	8.38e-05	14	34	2	38951500
Pubmed	An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis.	SMAD2 SMAD9	8.38e-05	14	34	2	25274628
Pubmed	Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture.	SMAD2 SMAD9	8.38e-05	14	34	2	33248111
Pubmed	The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord.	SMAD2 SMAD9	8.38e-05	14	34	2	16790475
Pubmed	Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.	SMAD2 SMAD9	8.38e-05	14	34	2	16435884
Pubmed	Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice.	SMAD2 SMAD9	9.66e-05	15	34	2	26116174
Pubmed	Tbx1 genetically interacts with the transforming growth factor-β/bone morphogenetic protein inhibitor Smad7 during great vessel remodeling.	SMAD2 SMAD9	9.66e-05	15	34	2	23011393
Pubmed	Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development.	SMAD2 SMAD9	9.66e-05	15	34	2	23946498
Pubmed	Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.	TIE1 ACE SMAD2	1.08e-04	94	34	3	20346360
Pubmed	Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon.	SMAD2 SMAD9	1.10e-04	16	34	2	21939397
Pubmed	Dynamic signaling network for the specification of embryonic pancreas and liver progenitors.	SMAD2 SMAD9	1.10e-04	16	34	2	19556507
Pubmed	SMAD4 is essential for generating subtypes of neurons during cerebellar development.	SMAD2 SMAD9	1.25e-04	17	34	2	22370000
Pubmed	Smad7 regulates terminal maturation of chondrocytes in the growth plate.	SMAD2 SMAD9	1.25e-04	17	34	2	23994637
Pubmed	p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.	SMAD2 SMAD9	1.41e-04	18	34	2	19717565
Pubmed	TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells.	SMAD2 SMAD9	1.41e-04	18	34	2	23546880
Pubmed	Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors.	SMAD2 SMAD9	1.41e-04	18	34	2	19914233
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	SMAD2 SMAD9	1.41e-04	18	34	2	35503090
Pubmed	Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung.	SMAD2 SMAD9	1.41e-04	18	34	2	27720610
Pubmed	Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.	SMAD2 SMAD9	1.57e-04	19	34	2	21957238
Pubmed	Augmented BMPRIA-mediated BMP signaling in cranial neural crest lineage leads to cleft palate formation and delayed tooth differentiation.	SMAD2 SMAD9	1.57e-04	19	34	2	23776616
Pubmed	Fgf9 signaling regulates small intestinal elongation and mesenchymal development.	SMAD2 SMAD9	1.74e-04	20	34	2	18653563
Pubmed	RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1.	SMAD2 SMAD9	1.74e-04	20	34	2	32662771
Pubmed	Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.	TIE1 SMAD2	1.93e-04	21	34	2	19015235
Pubmed	Myocardial smad4 is essential for cardiogenesis in mouse embryos.	SMAD2 SMAD9	2.12e-04	22	34	2	17585069
Pubmed	Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.	SMAD2 SMAD9	2.32e-04	23	34	2	30779601
Pubmed	Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse.	SMAD2 SMAD9	2.32e-04	23	34	2	30842446
Pubmed	Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.	SMAD2 SMAD9	2.32e-04	23	34	2	21937600
Pubmed	Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.	SMAD2 SMAD9	2.32e-04	23	34	2	29981310
Pubmed	Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling.	SMAD2 SMAD9	2.53e-04	24	34	2	16943282
Pubmed	Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration.	SMAD2 SMAD9	2.53e-04	24	34	2	34129836
Pubmed	Neural crest cell-autonomous roles of fibronectin in cardiovascular development.	SMAD2 SMAD9	2.53e-04	24	34	2	26552887
Pubmed	Fstl1 antagonizes BMP signaling and regulates ureter development.	SMAD2 SMAD9	2.74e-04	25	34	2	22485132
Pubmed	Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.	SMAD2 SMAD9	2.74e-04	25	34	2	20019329
Pubmed	Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.	TIE1 SMAD2	2.74e-04	25	34	2	24835278
Pubmed	The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.	SMAD2 SMAD9	2.97e-04	26	34	2	31311865
Pubmed	Spry1 and Spry2 are necessary for eyelid closure.	SMAD2 SMAD9	2.97e-04	26	34	2	24055172
Pubmed	Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.	SMAD2 SMAD9	3.45e-04	28	34	2	20346939
Pubmed	Single-cell analysis identifies a key role for Hhip in murine coronal suture development.	SMAD2 SMAD9	3.45e-04	28	34	2	34880220
Pubmed	Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.	SMAD2 SMAD9	3.97e-04	30	34	2	21880664
Pubmed	Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.	SMAD2 SMAD9	3.97e-04	30	34	2	23426374
Pubmed	ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.	SMAD2 SMAD9	4.24e-04	31	34	2	36445780
Pubmed	Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.	SMAD2 SMAD9	4.24e-04	31	34	2	25762570
Pubmed	The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development.	SMAD2 SMAD9	4.52e-04	32	34	2	25428587
Pubmed	Murine txk: a protein tyrosine kinase gene regulated by T cell activation.	FRK TIE1	4.52e-04	32	34	2	7542761
Pubmed	Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.	SMAD2 SMAD9	4.81e-04	33	34	2	33436499
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SPTBN4 TRPM4 POMT1 SSPOP NDUFB8 PPFIA2 SIL1	5.06e-04	1489	34	7	28611215
Pubmed	Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.	SMAD2 SMAD9	5.10e-04	34	34	2	19956733
Pubmed	O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.	SMAD2 SMAD9	5.72e-04	36	34	2	35167946
Pubmed	Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head.	SMAD2 SMAD9	6.05e-04	37	34	2	23592779
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ALKBH4 FOCAD C15orf39 TRPM4 SIL1 KIAA0319L	6.37e-04	1105	34	6	35748872
Pubmed	Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.	SMAD2 SMAD9	6.38e-04	38	34	2	22783020
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	TIE1 SMAD9	7.07e-04	40	34	2	27068110
GeneFamily	SMAD family	SMAD2 SMAD9	4.31e-05	8	23	2	750
GeneFamily	Dolichyl D-mannosyl phosphate dependent mannosyltransferases\|Phosphatidylinositol glycan anchor biosynthesis	POMT1 PIGM	5.54e-05	9	23	2	430
GeneFamily	Methyltransferase like	METTL23 METTL26	7.98e-04	33	23	2	963
GeneFamily	SH2 domain containing	FRK STAT6	7.24e-03	101	23	2	741
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 ACE KCNH4 SMAD9	8.16e-06	169	34	4	0d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 ACE KCNH4 SMAD9	9.79e-06	177	34	4	12f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TIE1 ACE KCNH4 SMAD9	9.79e-06	177	34	4	fdf2af00fc971f0cd3915e1416e4a256458d6ea8
Drug	AC1NDOB4	MGAM POMT1 PIGM	4.82e-06	23	33	3	CID004629010
Drug	dihydroxide	MGAM ACE SIL1	7.92e-06	27	33	3	CID003325224
Drug	aceanthrylene	ACE SIL1	1.22e-05	4	33	2	CID000107781
Disease	signal transducer and activator of transcription 6 measurement	NLRP12 STAT6	3.64e-06	3	33	2	EFO_0021916
Disease	renal fibrosis (implicated_via_orthology)	ACE STAT6	1.63e-04	17	33	2	DOID:0050855 (implicated_via_orthology)
Disease	1,5 anhydroglucitol measurement	MGAM MGAM2	4.83e-04	29	33	2	EFO_0008009

Protein segments in the cluster

Peptide	Gene	Start	Entry
IDPHLDDAWLWGERL	ALKBH4	166	Q9NXW9
LFAWEGWHNAAGIPL	ACE	186	P12821
LWLPQLHVGDWLVFD	AZIN2	371	Q96A70
WDVHEQFLWGPGLLI	MGAM2	701	Q2M2H8
DDVPHLLGLGWNWAS	KIAA0319L	146	Q8IZA0
TWDVHQQFLWGPGLL	MGAM	751	O43451
HIGFDWPGVWVHLDI	NPEPL1	451	Q8NDH3
NDPLLWDIGWLHELG	KCNH4	391	Q9UQ05
WGHISWDLLALPPQD	METTL23	81	Q86XA0
GLRLNWGEPMHWHLD	NDUFB8	96	O95169
HDLPQDAWLRWVLAG	POMT1	626	Q9Y6A1
GDKLQVLDTLHEGWW	FRK	66	P42685
HEFSWLIPRGWGLLD	CES3	346	Q6UWW8
LLLGLSASWLPWHQE	FOCAD	1691	Q5VW36
LQLWDDDLGALWACP	IL17RC	516	Q8NAC3
HEWIGNEWLPSLGLP	PPFIA2	1021	O75334
WEHWGGILPQSLDLL	METTL26	91	Q96S19
ASLQLPDLWWELGLE	RXFP3	41	Q9NSD7
LLHGLSLQWLGDWLV	SSPOP	276	A2VEC9
QLAWDLELWLDALLG	SMIM23	116	A6NLE4
QVHLLPGLWEQGWCE	SIL1	366	Q9H173
PGLWEQGWCEITAHL	SIL1	371	Q9H173
CWIEIHLHGPLQWLD	SMAD9	436	O15198
WGQVGHILELVDNWL	NCAPG2	716	Q86XI2
ETAWLNGLALPTWGH	C15orf39	1011	Q6ZRI6
GLLLHFLPRDWTWAE	ATG4D	156	Q86TL0
CWIELHLNGPLQWLD	SMAD2	436	Q15796
LLQPWLEGWHVEGTD	TIE1	546	P35590
LRHLLGDWLESQPWE	STAT6	26	P42226
GPHDLLWATLWEGQA	TECPR1	251	Q7Z6L1
SQLEQGELPWGLDPW	ZNF620	61	Q6ZNG0
DEWLPHLELGWHKLL	SPTBN4	1171	Q9H254
HLELGWHKLLGLWEA	SPTBN4	1176	Q9H254
HWGEWLLNLKVAPAG	PIGM	6	Q9H3S5
DAGLGQAPWSDLLLW	TRPM4	551	Q8TD43
NDLGDWGLWLLAEGL	NLRP12	951	P59046
WGLWLLAEGLQHPAC	NLRP12	956	P59046