Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF573 IKZF2 ZBTB17 ZBTB4 ZFP28 ZNF571 IKZF1 ZBTB41 ZNF217 ZNF510 STOX1 ZNF229 ZNF668 ZSCAN5B ZNF776 GRHL1 ZNF676 ZSCAN21 ASCL2 ZNF587 ZNF746 ZNF837 ZNF816 DMRTC2 DMRTA1 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 PURG ZNF513	2.55e-10	1459	132	33	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF573 ZBTB17 ZBTB4 ZFP28 ZNF571 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF668 ZSCAN5B ZNF776 GRHL1 ZNF676 ZSCAN21 ASCL2 ZNF587 ZNF746 ZNF837 ZNF816 DMRTC2 DMRTA1 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 PURG ZNF513	2.08e-09	1412	132	31	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF573 IKZF2 ZBTB17 ZBTB4 ZFP28 ZNF571 IKZF1 ZBTB41 ZNF217 ZNF229 ZNF668 ZSCAN5B ZNF776 GRHL1 ZNF676 ZSCAN21 ASCL2 ZNF587 ZNF746 ZNF837 ZNF816 DMRTC2 DMRTA1 ZNF761 ZNF615 ZNF782 ZFP62 ZNF513	8.65e-09	1244	132	28	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF573 IKZF2 ZBTB17 ZBTB4 ZFP28 ZNF571 IKZF1 ZBTB41 ZNF217 ZNF229 ZNF668 ZSCAN5B ZNF776 GRHL1 ZNF676 ZSCAN21 ASCL2 ZNF587 ZNF746 ZNF837 ZNF816 DMRTC2 DMRTA1 ZNF761 ZNF615 ZNF782 ZFP62 ZNF513	1.38e-08	1271	132	28	GO:0000987
GeneOntologyMolecularFunction	actin filament binding	MYO7B MYO9A MYO9B MYO18A CLASP2 NEB PHPT1 MAP1S MACF1	2.05e-05	227	132	9	GO:0051015
Domain	zf-C2H2	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	8.91e-18	693	131	32	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	2.77e-17	775	131	33	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	2.99e-17	777	131	33	PS00028
Domain	Znf_C2H2-like	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	6.11e-17	796	131	33	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	8.06e-17	694	131	31	IPR013087
Domain	Znf_C2H2	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	8.50e-17	805	131	33	IPR007087
Domain	ZnF_C2H2	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	9.49e-17	808	131	33	SM00355
Domain	-	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF668 ZSCAN5B ZNF776 ZNF676 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	3.72e-16	679	131	30	3.30.160.60
Domain	zf-C2H2_6	ZNF573 ZFP28 ZNF571 ZBTB41 ZNF229 ZNF668 ZSCAN5B ZNF676 ZNF587 ZNF746 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62	7.39e-11	314	131	17	PF13912
Domain	KRAB	ZNF573 ZFP28 ZNF571 ZNF233 ZNF510 ZNF229 ZNF230 ZNF776 ZNF676 ZNF587 ZNF746 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582	5.61e-10	358	131	17	PS50805
Domain	KRAB	ZNF573 ZFP28 ZNF571 ZNF233 ZNF510 ZNF229 ZNF230 ZNF776 ZNF676 ZNF587 ZNF746 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582	8.91e-10	369	131	17	SM00349
Domain	KRAB	ZNF573 ZFP28 ZNF571 ZNF233 ZNF510 ZNF229 ZNF230 ZNF776 ZNF676 ZNF587 ZNF746 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582	9.28e-10	370	131	17	IPR001909
Domain	KRAB	ZNF573 ZFP28 ZNF571 ZNF233 ZNF510 ZNF229 ZNF230 ZNF776 ZNF587 ZNF746 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582	4.46e-09	358	131	16	PF01352
Domain	IQ	MYO7B MYO9A MYO9B MYO18A LRRIQ1 IQUB	4.91e-05	93	131	6	PS50096
Domain	IQ	MYO7B MYO9A MYO9B MYO18A LRRIQ1	1.41e-04	71	131	5	PF00612
Domain	Myosin_head_motor_dom	MYO7B MYO9A MYO9B MYO18A	1.42e-04	38	131	4	IPR001609
Domain	MYOSIN_MOTOR	MYO7B MYO9A MYO9B MYO18A	1.42e-04	38	131	4	PS51456
Domain	Myosin_head	MYO7B MYO9A MYO9B MYO18A	1.42e-04	38	131	4	PF00063
Domain	MYSc	MYO7B MYO9A MYO9B MYO18A	1.42e-04	38	131	4	SM00242
Domain	IQ	MYO7B MYO9A MYO9B MYO18A LRRIQ1	2.63e-04	81	131	5	SM00015
Domain	Ubiquitin-rel_dom	RALGDS MYO7B MYO9A MYO9B RGS12 NUB1 IQUB	3.21e-04	184	131	7	IPR029071
Domain	IQ_motif_EF-hand-BS	MYO7B MYO9A MYO9B MYO18A LRRIQ1	4.29e-04	90	131	5	IPR000048
Domain	Pyr_OxRdtase_I_AS	TXNRD1 DLD	4.82e-04	5	131	2	IPR012999
Domain	Pyr_redox_dim	TXNRD1 DLD	4.82e-04	5	131	2	PF02852
Domain	PYRIDINE_REDOX_1	TXNRD1 DLD	4.82e-04	5	131	2	PS00076
Domain	PQQ_repeat	EMC1 ZNF106	7.19e-04	6	131	2	IPR002372
Domain	DM_2	DMRTC2 DMRTA1	1.00e-03	7	131	2	PS50809
Domain	-	TXNRD1 DLD	1.00e-03	7	131	2	3.30.390.30
Domain	DM	DMRTC2 DMRTA1	1.00e-03	7	131	2	SM00301
Domain	-	DMRTC2 DMRTA1	1.00e-03	7	131	2	4.10.1040.10
Domain	DM_DNA-bd	DMRTC2 DMRTA1	1.00e-03	7	131	2	IPR001275
Domain	DM	DMRTC2 DMRTA1	1.00e-03	7	131	2	PF00751
Domain	DM_1	DMRTC2 DMRTA1	1.00e-03	7	131	2	PS40000
Domain	RA	RALGDS MYO9A MYO9B	1.31e-03	31	131	3	SM00314
Domain	Pyr_nucl-diS_OxRdtase_dimer	TXNRD1 DLD	1.33e-03	8	131	2	IPR004099
Domain	FAD/NAD-linked_Rdtase_dimer	TXNRD1 DLD	1.33e-03	8	131	2	IPR016156
Domain	DMRT/dsx/mab-3	DMRTC2 DMRTA1	1.33e-03	8	131	2	IPR026607
Domain	RA	RALGDS MYO9A MYO9B	2.03e-03	36	131	3	PF00788
Domain	RA	RALGDS MYO9A MYO9B	2.20e-03	37	131	3	PS50200
Pubmed	A human MAP kinase interactome.	RALGDS MYO9A KIAA0232 MYO18A ARHGAP17 CHD8 NEB PNISR PIAS1 LENG8 ZNF106 MACF1 OBI1 HDLBP	7.34e-09	486	135	14	20936779
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYO9B UBR4 ZBTB4 DYRK1A ARHGAP17 CHD8 CLASP2 NDUFA1 HUWE1 ANKHD1 ADGRA2 SH2B2 SYNE4 PLEKHM1 PNPLA6 MAP1S SUGP2 SND1 RRP12	5.95e-08	1105	135	19	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 RALGDS EMC1 GON4L CHD8 ANKHD1 PIAS1 RGS3 PIK3R4 TSR1 ASPH DOCK7 CARD6 ILVBL	2.64e-07	650	135	14	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UBR4 NCBP1 CHD8 HUWE1 ANKHD1 PAICS SUGP2 SND1 TSR1 RRP12 DOCK7 DLD MACF1 HDLBP	2.79e-07	653	135	14	22586326
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF775 ZNF233 STOX1 ZNF230 ZNF469	6.20e-07	42	135	5	34673265
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SMG1 CASC3 RBM12B MYO18A NCBP1 ANKHD1 PNISR NGRN RBM12 SUGP2 SND1 RRP12 MACF1 PURG HDLBP	6.24e-07	807	135	15	22681889
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CASC3 MYO9B CHD8 ZNF217 HUWE1 SHOC1 MACF1 NEURL1B SLC4A5 GOLGA3	7.53e-07	332	135	10	37433992
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	UBR4 CHD8 ZNF217 HUWE1 ANKHD1 ZNF608 DOCK7 OBI1 SLC39A7 GOLGA3 WDR62	7.82e-07	418	135	11	34709266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CASC3 EMC1 MYO9A KIAA0232 DYRK1A ARHGAP17 CLASP2 RGS12 PIK3R4 ZNF106 DOCK7 MACF1 NUB1 OBI1 WDR62	1.39e-06	861	135	15	36931259
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM12B MYO9B MYO18A BARD1 NCBP1 PIK3R4 ZNF668 SUGP2 SND1 TSR1 RRP12 ASPH DLD MACF1	1.65e-06	759	135	14	35915203
Pubmed	Tails of unconventional myosins.	MYO7B MYO9A MYO9B	1.98e-06	7	135	3	11212352
Pubmed	Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.	CASC3 NCBP1 PAICS	3.16e-06	8	135	3	15680326
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	CHGA HUWE1 ANKHD1 PNPLA6 MACF1	3.18e-06	58	135	5	37117185
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYO9B UBR4 MYO18A DYRK1A ANKHD1 PNPLA6 SUGP2 TSR1 ASPH DOCK7 MACF1 HDLBP	4.27e-06	601	135	12	33658012
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CASC3 EMC1 DYRK1A GON4L CHD8 CLASP2 ZNF217 ANKHD1 PNISR PIAS1 LENG8 PNPLA6 SND1 TSR1 RRP12 ASPH MACF1 ILVBL HDLBP	5.56e-06	1497	135	19	31527615
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 RALGDS EMC1 CHD8 ANKHD1 ADGRA2 RBM12 ZNF608 TSR1 SULF1 MAML2	7.46e-06	529	135	11	14621295
Pubmed	Human transcription factor protein interaction networks.	ASNSD1 SMG1 UBR4 MYO18A GON4L CHD8 ZNF217 ANKHD1 PIAS1 LENG8 RBM12 ZNF608 SUGP2 ZSCAN21 ZNF746 RRP12 DLD ILVBL	1.11e-05	1429	135	18	35140242
Pubmed	IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.	UBR4 IKZF1	1.50e-05	2	135	2	38885295
Pubmed	Helios deficiency has minimal impact on T cell development and function.	IKZF2 IKZF1	1.50e-05	2	135	2	19620299
Pubmed	Regulation of human MutYH DNA glycosylase by the E3 ubiquitin ligase mule.	HUWE1 MUTYH	1.50e-05	2	135	2	24443563
Pubmed	Class IX Myosins: Motorized RhoGAP Signaling Molecules.	MYO9A MYO9B	1.50e-05	2	135	2	32451867
Pubmed	Visualizing late states of human 40S ribosomal subunit maturation.	TSR1 RRP12	1.50e-05	2	135	2	29875412
Pubmed	Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.	ZNF510 ZNF782	1.50e-05	2	135	2	19030899
Pubmed	Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.	IKZF2 IKZF1	1.50e-05	2	135	2	17681952
Pubmed	[Expression characteristics of isoforms of Ikaros and Helios in patients with leukemia and their mechanism].	IKZF2 IKZF1	1.50e-05	2	135	2	22931634
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO7B MYO9A MYO9B	2.02e-05	14	135	3	8022818
Pubmed	Functional proteomics mapping of a human signaling pathway.	SMG1 UBR4 ZNF510 HUWE1 PIAS1 RGS3 ZNF106 DKK1 ZNF587 MACF1 HDLBP	2.08e-05	591	135	11	15231748
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	UBR4 DYRK1A PNISR SUGP2 TSR1 RRP12 ASPH ILVBL	2.40e-05	300	135	8	28561026
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 KIAA0232 CHD8 ADGRA2 RBM12 ZNF608 MACF1	2.97e-05	225	135	7	12168954
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EMC1 UBR4 NCBP1 CLASP2 HUWE1 ANKHD1 PAICS SIRT5 TXNRD1 RPS26P11 MAP1S SND1 TSR1 RRP12 ASPH MACF1 HDLBP	3.61e-05	1415	135	17	28515276
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IFT172 UBR4 ZBTB4 DYRK1A NCBP1 HUWE1 PNISR LRP1B PIAS1 PAICS ME3 PIK3R4 MAP1S SULF1 MACF1 GOLGA3	4.08e-05	1285	135	16	35914814
Pubmed	The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.	SMG1 CASC3 NCBP1	4.47e-05	18	135	3	25220460
Pubmed	Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.	IKZF2 IKZF1	4.48e-05	3	135	2	11937265
Pubmed	Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.	IKZF2 IKZF1	4.48e-05	3	135	2	9560339
Pubmed	Analysis of Ikaros family splicing variants in human hematopoietic lineages.	IKZF2 IKZF1	4.48e-05	3	135	2	20432734
Pubmed	Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes.	IKZF2 IKZF1	4.48e-05	3	135	2	27502439
Pubmed	Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions.	DYRK1A CHD8	4.48e-05	3	135	2	38622540
Pubmed	Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma.	IKZF2 IKZF1	4.48e-05	3	135	2	18332232
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MYO18A ZNF217 HUWE1 PNISR ZNF106 PNPLA6 MAP1S SUGP2 RRP12 ASPH WDR62 HDLBP	5.17e-05	774	135	12	15302935
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	GON4L CLASP2 HUWE1 SUGP2 SND1 TSR1 RRP12 ASPH ILVBL HDLBP	5.81e-05	547	135	10	37267103
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF233 ZNF229 ZNF230	6.21e-05	20	135	3	12743021
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	MYO9B GON4L NCBP1 CHD8 PAICS TGFB3 LENG8 PHPT1 ZNF608 SULF1 NUB1 NEURL1B MUTYH ZFP62 CFAP46	7.93e-05	1215	135	15	15146197
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	CASC3 MYO9B NCBP1 XYLT2 LENG8 SUGP2 SND1 ASPH PURG	8.51e-05	462	135	9	31138677
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHD8 ZNF217 LENG8 GRHL1 RBM12 ZNF608 ZSCAN21	8.92e-05	268	135	7	33640491
Pubmed	The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.	ZBTB17 HUWE1	8.93e-05	4	135	2	16269333
Pubmed	Involvement of doublesex and mab-3-related transcription factors in human female germ cell development demonstrated by xenograft and interference RNA strategies.	DMRTC2 DMRTA1	8.93e-05	4	135	2	25082981
Pubmed	BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.	MYO9A MYO9B	8.93e-05	4	135	2	15644318
Pubmed	TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.	UBR4 HUWE1	8.93e-05	4	135	2	37324936
Pubmed	Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice.	PNPLA6 ASCL2	8.93e-05	4	135	2	14749382
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	MYO9B NCBP1 ANKHD1 PNPLA6 SND1 TSR1 RRP12 OBI1	9.31e-05	364	135	8	24778252
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MYO9A MYO9B ARHGAP17 ZNF217 HUWE1 PIAS1 DLD MACF1 OBI1 HDLBP	1.05e-04	588	135	10	38580884
Pubmed	Agrin has a pathological role in the progression of oral cancer.	PNPLA6 MAP1S SND1 ASPH SLC39A7 HDLBP	1.25e-04	197	135	6	29872149
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBR4 HUWE1 NUB1 OBI1	1.30e-04	66	135	4	24811749
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	UBR4 ARHGAP17 HUWE1 ANKHD1 RRP12 DOCK7 HDLBP	1.39e-04	288	135	7	23383273
Pubmed	The functional interactome landscape of the human histone deacetylase family.	IKZF2 RBM12B IKZF1 ZNF217 HUWE1 RRP12 OBI1	1.42e-04	289	135	7	23752268
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	CASC3 DYRK1A NCBP1 ZNF106 DLD HDLBP	1.48e-04	203	135	6	35012549
Pubmed	Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.	LRP1B DKK1	1.48e-04	5	135	2	20383322
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	CLASP2 MACF1	1.48e-04	5	135	2	17113391
Pubmed	Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.	BARD1 NCBP1	1.48e-04	5	135	2	20379136
Pubmed	Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer.	NKD1 DKK1	1.48e-04	5	135	2	27846906
Pubmed	Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.	IKZF2 IKZF1	1.48e-04	5	135	2	10978333
Pubmed	Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation.	ZBTB17 ZBTB4	1.48e-04	5	135	2	18451802
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	SMG1 UBR4 MAP1S SUGP2 RRP12 MACF1 OBI1 ILVBL HDLBP	1.50e-04	498	135	9	36634849
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 UBR4 MYO18A NCBP1 ZBTB41 STOX1 NEB PNISR CAPN11 ZNF608 SND1 DLD MACF1 ITIH6 OBI1 CFAP46	1.56e-04	1442	135	16	35575683
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	UBR4 MYO18A CLASP2 HUWE1 ANKHD1 PAICS LRRIQ1 SND1 TSR1 RRP12 DOCK7 MACF1 OBI1 HDLBP	1.59e-04	1149	135	14	35446349
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MYO9A CLASP2 DOCK7 MACF1 GOLGA3 WDR62	1.73e-04	209	135	6	36779422
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	UBR4 HUWE1 PAICS TSR1 ASPH DOCK7 ILVBL SLC39A7	1.75e-04	399	135	8	37536630
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ASNSD1 ZCWPW1 UBR4 DYRK1A CHD8 CLASP2 ZNF217 PIAS1 XYLT2 LENG8 ZNF106 GJB5 MAML2 OBI1 HDLBP	2.07e-04	1327	135	15	32694731
Pubmed	Affinity proteomic dissection of the human nuclear cap-binding complex interactome.	NCBP1 LENG8	2.22e-04	6	135	2	32960270
Pubmed	Elucidating mechanisms of osteogenesis in human adipose-derived stromal cells via microarray analysis.	TGFB3 DKK1	2.22e-04	6	135	2	20613589
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	DYRK1A NCBP1 CHD8 PIAS1 ZNF106 ZNF668 NKD1 ZNF608 RRP12 ASPH DOCK7 ILVBL SLC39A7 ZFP62	2.54e-04	1203	135	14	29180619
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYO9A MYO9B UBR4 CHD8 HUWE1 ANKHD1 PAICS PIK3R4 PNPLA6 SUGP2 SND1 RRP12 ASPH MACF1 HDLBP	2.55e-04	1353	135	15	29467282
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ASNSD1 CASC3 NCBP1 CLASP2 ANKHD1 CWC25 LENG8 NGRN DKK1 SUGP2 TSR1 ASPH DOCK7 SLC39A7 HDLBP	2.94e-04	1371	135	15	36244648
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DYRK1A BARD1 NCBP1 CLASP2 PIAS1 PAICS ZSCAN21 TSR1 NUB1 ILVBL	3.00e-04	670	135	10	22990118
Pubmed	Sexually dimorphic expression of multiple doublesex-related genes in the embryonic mouse gonad.	DMRTC2 DMRTA1	3.10e-04	7	135	2	12609607
Pubmed	The function of Dmrt genes in vertebrate development: it is not just about sex.	DMRTC2 DMRTA1	3.10e-04	7	135	2	17720152
Pubmed	ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.	CLASP2 MACF1	3.10e-04	7	135	2	20937854
Pubmed	Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA.	DMRTC2 DMRTA1	3.10e-04	7	135	2	17605809
Pubmed	Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.	ZBTB17 HUWE1	3.10e-04	7	135	2	23699408
Pubmed	The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression.	BARD1 HUWE1	3.10e-04	7	135	2	33542213
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	UBR4 ANKHD1 RGS3 PLEKHM1 NUB1 SLC39A7	3.10e-04	233	135	6	37704626
Pubmed	Network organization of the human autophagy system.	PIK3R4 MAP1S SND1 ASPH SMCR8 ILVBL GOLGA3 WDR62	3.22e-04	437	135	8	20562859
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	UBR4 NCBP1 CHD8 HUWE1 PAICS TXNRD1 RPS26P11 SND1 DLD MACF1 HDLBP	3.24e-04	807	135	11	30575818
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	IKZF2 ZNF775 ZBTB17 ZFP28 ZBTB41 PIAS1 ZNF668 ZSCAN5B GRHL1 ZSCAN21 ZNF513	3.28e-04	808	135	11	20412781
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	PIAS1 TXNRD1 SND1	3.42e-04	35	135	3	24515614
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	ANKHD1 TXNRD1 DOCK7 WDR62 HDLBP	3.69e-04	156	135	5	32850835
Pubmed	Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.	UBR4 HUWE1 SUGP2	3.72e-04	36	135	3	35379950
Pubmed	Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.	ZBTB17 PIAS1	4.12e-04	8	135	2	16522640
Pubmed	Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death.	ZBTB17 HUWE1	4.12e-04	8	135	2	26212014
Pubmed	Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination.	DMRTC2 DMRTA1	4.12e-04	8	135	2	11863363
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	RBM12B MAP1S SUGP2 DOCK7 OBI1 WDR62	4.23e-04	247	135	6	32989298
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EMC1 UBR4 NCBP1 CLASP2 HUWE1 ANKHD1 PAICS PIK3R4 RPS26P11 SND1 TSR1 RRP12 DOCK7 DLD HDLBP	4.40e-04	1425	135	15	30948266
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	CASC3 RBM12B HUWE1 LENG8 SUGP2 TSR1 RRP12	4.46e-04	349	135	7	25665578
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYO9A MYO18A DYRK1A CLASP2 PIK3R4 PNPLA6 MAP1S SUGP2 SND1 DOCK7 DLD MACF1 SLC39A7 GOLGA3 HDLBP	4.60e-04	1431	135	15	37142655
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	NCBP1 HUWE1 XYLT2 SUGP2 TSR1 RRP12	4.60e-04	251	135	6	28077445
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	MYO18A CHD8 HUWE1 ANKHD1 SIRT5 PNPLA6 PHPT1 TSR1	4.78e-04	464	135	8	32457219
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	EMC1 UBR4 MYO18A HUWE1 LRP1B PHPT1 MAP1S SUGP2 DOCK7 DLD MACF1 SLC39A7 HDLBP	5.10e-04	1139	135	13	36417873
Pubmed	Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons.	IKZF2 IKZF1	5.29e-04	9	135	2	22142223
Pubmed	Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.	IFT172 RBM12	5.29e-04	9	135	2	22384391
Pubmed	Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.	IKZF2 IKZF1	5.29e-04	9	135	2	22638570
Interaction	ZFP37 interactions	ZBTB17 ZFP28 ZSCAN21 ZNF746 ZFP62 ZNF513	8.17e-07	49	133	6	int:ZFP37
Interaction	ZNF667 interactions	ZBTB17 ZFP28 ZSCAN21 ZNF746 ZFP62 ZNF513	1.31e-06	53	133	6	int:ZNF667
Interaction	ZNF287 interactions	ZBTB17 ZFP28 ZSCAN21 ZNF746 ZFP62 ZNF513	2.76e-06	60	133	6	int:ZNF287
Interaction	ZFP62 interactions	ZBTB17 ZFP28 ZNF668 ZSCAN21 ZFP62 PURG ZNF513	4.18e-06	99	133	7	int:ZFP62
Interaction	NOTCH2 interactions	ZNF775 ZBTB17 DYRK1A ZNF668 RPS26P11 LRRIQ1 ZSCAN21 SULF1 ZNF746 ASPH ZNF761 MAML2 ZNF791	4.66e-06	423	133	13	int:NOTCH2
Interaction	SMG7 interactions	SMG1 PLEKHA4 CHD8 ZNF217 LENG8 ZNF106 RBM12 ZNF608 TSR1 RRP12 OBI1	8.93e-06	319	133	11	int:SMG7
Interaction	AURKB interactions	RBM12B UBR4 PLEKHA4 BARD1 HUWE1 SIRT5 RPS26P11 MAP1S SUGP2 TSR1 RRP12 DOCK7 MACF1 ZNF782 OBI1 ILVBL WDR62	1.11e-05	761	133	17	int:AURKB
Interaction	SEM1 interactions	UBR4 HUWE1 PIAS1 TXNRD1 LENG8 SND1 NUB1 OBI1	1.23e-05	162	133	8	int:SEM1
Interaction	PRDM5 interactions	CASC3 ZBTB17 ZBTB4 ZFP28 NGRN ZFP62	1.49e-05	80	133	6	int:PRDM5
Interaction	ZNF467 interactions	LENG8 ZNF668 RPS26P11 ZSCAN21 RRP12 ZNF761 ZNF791 ZFP62	2.52e-05	179	133	8	int:ZNF467
Interaction	ZNF473 interactions	ZFP28 ZSCAN21 ZNF837 ZFP62 ZNF513	3.38e-05	56	133	5	int:ZNF473
Interaction	ZFP3 interactions	ZFP28 ZSCAN21 ZFP62 ZNF513	4.35e-05	30	133	4	int:ZFP3
Interaction	CTCFL interactions	PLEKHA4 ZFP28 ZSCAN21 ZFP62 ZNF513	5.56e-05	62	133	5	int:CTCFL
Interaction	GZF1 interactions	ZFP28 ZSCAN21 ZFP62 PURG ZNF513 HDLBP	6.25e-05	103	133	6	int:GZF1
Interaction	ZNF382 interactions	ZFP28 ZSCAN21 ZFP62 ZNF513	6.39e-05	33	133	4	int:ZNF382
Interaction	ZNF787 interactions	PLEKHA4 ZFP28 ZSCAN21 ZFP62 ZNF513	6.48e-05	64	133	5	int:ZNF787
Interaction	ZNF513 interactions	ZFP28 ZSCAN21 ZFP62 ZNF513	7.21e-05	34	133	4	int:ZNF513
Interaction	SRPK2 interactions	UBR4 DYRK1A BARD1 NCBP1 CLASP2 PNISR ZNF668 MAP1S RRP12 ADAMTS18 MACF1 OBI1 ZFP62 PURG HDLBP	7.93e-05	717	133	15	int:SRPK2
Interaction	ZNF652 interactions	ZFP28 ZSCAN21 ZFP62 ZNF513	8.10e-05	35	133	4	int:ZNF652
Interaction	ZFP28 interactions	ZFP28 ZSCAN21 ZFP62 ZNF513	1.01e-04	37	133	4	int:ZFP28
Interaction	PURG interactions	CASC3 LENG8 ZNF668 SUGP2 RRP12 ZNF791 ZFP62 PURG	1.19e-04	223	133	8	int:PURG
Interaction	ZNF423 interactions	ZBTB17 ZFP28 ZSCAN21 ZFP62 ZNF513	1.22e-04	73	133	5	int:ZNF423
Interaction	YWHAB interactions	CASC3 EMC1 MYO9A KIAA0232 PLEKHA4 DYRK1A CLASP2 NEB RGS3 PAICS RGS12 PIK3R4 ZNF106 DOCK7 DLD MACF1 NUB1 WDR62	1.22e-04	1014	133	18	int:YWHAB
Interaction	ZBTB17 interactions	ZBTB17 ZBTB4 HUWE1 ZNF746 ZFP62	1.57e-04	77	133	5	int:ZBTB17
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF573 PLEKHA4 ZFP28 ZNF571 ZNF233 ZNF229 ZNF230 SYNE4 LENG8 ZSCAN5B ZNF776 ZNF587 ZNF837 ZNF816 DMRTC2 ZNF761 ZNF615 ZNF582 WDR62	2.46e-09	1192	135	19	chr19q13
Cytoband	19q13.43	ZSCAN5B ZNF776 ZNF587 ZNF837 ZNF582	6.21e-06	87	135	5	19q13.43
Cytoband	19q13.12	ZNF573 ZNF571 SYNE4 WDR62	6.30e-05	72	135	4	19q13.12
Cytoband	19q13.31	ZNF233 ZNF229 ZNF230	8.59e-05	29	135	3	19q13.31
Cytoband	1p36.13	EMC1 ZBTB17 UBR4	6.15e-04	56	135	3	1p36.13
Cytoband	2q21.2	LRP1B ANKRD30BL	7.63e-04	14	135	2	2q21.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF573 IKZF2 ZNF775 ZBTB17 ZBTB4 ZFP28 ZNF571 ZNF233 IKZF1 ZBTB41 ZNF217 ZNF510 ZNF229 ZNF230 ZNF106 ZNF668 ZSCAN5B ZNF776 ZNF469 ZNF676 ZNF608 ZSCAN21 ZNF587 ZNF746 ZNF837 ZNF816 ZNF761 ZNF615 ZNF782 ZNF791 ZNF582 ZFP62 ZNF513	2.13e-23	718	91	33	28
GeneFamily	Myosins, class IX	MYO9A MYO9B	2.51e-05	2	91	2	1103
Coexpression	SANSOM_APC_TARGETS	CLASP2 NEB PAICS RGS12 ZSCAN21 ASCL2 ZNF746 MUTYH WDR62	1.44e-06	209	135	9	M1755
Coexpression	SANSOM_APC_TARGETS	CLASP2 NEB PAICS RGS12 ZSCAN21 ASCL2 ZNF746 MUTYH WDR62	5.29e-06	245	135	9	MM735
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Unfolded_protein_responsible_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	ANKHD1 CWC25 SND1 ASCL2 ZNF791 SLC39A7 GOLGA3	2.64e-06	200	135	7	e68e44ab57d17ac4845d9e3798814d048d79e888
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RALGDS IKZF2 ARHGAP17 NEB PIK3R4 ZNF746	1.21e-05	167	135	6	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO9A CHGA ZNF106 MACF1 MAML2	1.48e-05	173	135	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO9A CHGA ZNF106 MACF1 MAML2	1.48e-05	173	135	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO9A CHGA ZNF106 MACF1 MAML2	1.48e-05	173	135	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MYO9A IKZF1 CHGA MACF1 MAML2	1.58e-05	175	135	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 IKZF2 LENG8 GRHL1 ZNF587 MACF1	1.79e-05	179	135	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 UBR4 CHGA NEB SLC39A7 HDLBP	2.74e-05	193	135	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 UBR4 CHGA NEB SLC39A7 HDLBP	2.74e-05	193	135	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TGFB3 TMEM132C ZNF106 NKD1 MACF1 EPHA3	3.07e-05	197	135	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Brain_organoid-organoid_Tanaka_cellReport\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	PLEKHA4 NEB SLC7A8 ZNF106 SULF1 HDLBP	3.34e-05	200	135	6	b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-BMP_responsible_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	PLEKHA4 TMEM132C SLC7A8 LRRIQ1 SULF1 SLC4A5	3.34e-05	200	135	6	a4b52466b6426a835655b5fe7487e15aea816e14
Disease	keratoconus	LRP1B ZNF106 ZNF469 MAML2	1.86e-04	66	126	4	MONDO_0015486
Disease	asparaginase-induced acute pancreatitis	NEB ADAMTS18	6.39e-04	9	126	2	EFO_1001507
Disease	total blood protein measurement	IKZF1 RGS3 RGS12 SLC7A8 SND1 MACF1 MAML2 HDLBP	7.10e-04	449	126	8	EFO_0004536
Disease	corpus callosum posterior volume measurement	ZBTB4 SND1 EPHA3	1.44e-03	52	126	3	EFO_0010298
Disease	calcium measurement	MYO18A CHD8 LRP1B RGS12 GRHL1 SND1 SHOC1 MACF1 NEURL1B	1.54e-03	628	126	9	EFO_0004838
Disease	polycystic kidney disease (implicated_via_orthology)	IFT172 XYLT2	1.59e-03	14	126	2	DOID:0080322 (implicated_via_orthology)
Disease	basophil measurement	DYRK1A SLC7A8 ZNF469	2.18e-03	60	126	3	EFO_0803539
Disease	glucose homeostasis measurement, acute insulin response measurement	IKZF1 DMRTA1	2.65e-03	18	126	2	EFO_0006831, EFO_0006896
Disease	cortical thickness	STOX1 ADGRA2 PLEKHM1 ZNF106 ZNF469 LRRIQ1 SND1 DOCK7 ADAMTS18 MACF1 DMRTA1 EPHA3	2.95e-03	1113	126	12	EFO_0004840
Disease	response to methotrexate, neurotoxicity	PNPLA6 MACF1	2.95e-03	19	126	2	EFO_0011057, GO_0031427
Disease	cholesterol to total lipids in very small VLDL percentage	ZNF229 RGS12 DOCK7	2.98e-03	67	126	3	EFO_0022245
Disease	Mental Retardation, Psychosocial	RALGDS GON4L CHD8 WDR62	3.03e-03	139	126	4	C0025363
Disease	Profound Mental Retardation	RALGDS GON4L CHD8 WDR62	3.03e-03	139	126	4	C0020796
Disease	Mental deficiency	RALGDS GON4L CHD8 WDR62	3.03e-03	139	126	4	C0917816
Disease	Colorectal Carcinoma	RALGDS ZNF217 NDUFA1 TXNRD1 ADAMTS18 DMRTA1 MUTYH IQUB EPHA3	3.24e-03	702	126	9	C0009402
Disease	breast cancer, COVID-19	GON4L PLEKHM1	3.95e-03	22	126	2	MONDO_0007254, MONDO_0100096
Disease	basophil percentage of leukocytes	IKZF2 DYRK1A IKZF1 SLC7A8 ZNF469	3.96e-03	243	126	5	EFO_0007992
Disease	physical activity measurement	IKZF1 RGS12 ZNF668 DMRTA1 PURG	4.10e-03	245	126	5	EFO_0008002
Disease	intellectual disability (implicated_via_orthology)	UBR4 DYRK1A CAPN11	4.10e-03	75	126	3	DOID:1059 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HAEQAIGQLKRHGKN	BAAT	336	Q14032
GKRNSNRAHQGKHET	CCL28	106	Q9NRJ3
NGKKGHHTETVFNRV	CHD8	2391	Q9HCK8
LENNGKRGHHNRLSS	BARD1	316	Q99728
AEQKRGHGMKNHSRS	CWC25	246	Q9NXE8
RAHKSRAKGHRAGEA	ADGRA2	1181	Q96PE1
KAAGHLRRLGNENDK	CFAP46	561	Q8IYW2
QEKHLGKLHRAASRG	ANKRD26P1	46	Q6NSI1
GARRETKHGGHKNGR	ASPH	31	Q12797
KRRHQQGQGDDSSHK	DYRK1A	116	Q13627
HINNSRLKAKGVGQH	CAPN11	41	Q9UMQ6
IGKNGKRHDHAILLT	ADAMTS18	376	Q8TE60
QALRQHVPHGGASKK	ASCL2	71	Q99929
KHKHRAKESQQGCRG	NKD1	401	Q969G9
AVHLLKDHVGRNNGN	RBM12	331	Q9NTZ6
LKHHDGRNNGDAIVK	RBM12B	186	Q8IXT5
ARKRITHAKVQGAGQ	RGS3	126	P49796
RHRNNTEKKHPGGGE	SLC7A8	6	Q9UHI5
NHQRLVHIKGNCGKE	NUB1	321	Q9Y5A7
HHAKAGTIIARQGDQ	PNPLA6	531	Q8IY17
RAHANGSVRRGHKND	LRP1B	2101	Q9NZR2
IVKGQRSLHHRGDNL	MAP1S	71	Q66K74
HSDENDGGQPHKRRK	NCBP1	6	Q09161
LKKAGLAHSLQHLRG	NGRN	141	Q9NPE2
HGAKHGSADNRKLSA	MDFIC	111	Q9P1T7
NKDNIGFHHLGKRIN	MEPE	41	Q9NQ76
KITDHGHGRLLEAQK	GUCY2D	681	Q02846
REGTNQHHRALGKKA	ASMTL	396	O95671
ELKKQKRAARFQHGH	LENG8	506	Q96PV6
LKHGEKAERNIHTGS	KIAA0232	336	Q92628
SAIFKHQHKGGTLQR	MYO18A	711	Q92614
VQAGGSKKHSNHLRK	OBI1	411	Q5W0B1
QKGNLLRHIKLHSGE	IKZF1	156	Q13422
AAAKVEAGHNRRHFK	GOLGA3	1196	Q08378
QKGNLLRHIKLHSGE	IKZF2	151	Q9UKS7
FQIQRSGGRKHTEKH	HUWE1	3301	Q7Z6Z7
GKGNLEVNRNKSSHH	GPR75	411	O95800
VNREKKNQAHRHSAG	LRRIQ1	1696	Q96JM4
NLGEKIAHRQHKLEG	MACF1	6206	Q9UPN3
RVARTQGGANAHKHV	IFT172	1076	Q9UG01
QHGQGARKAGKHTKA	MAML2	81	Q8IZL2
QLLHKVDKASVRHGG	ILVBL	41	A1L0T0
HGNQLGIDKRGHLTA	GRHL1	126	Q9NZI5
QAKAHHSKAGQKRGG	CARD6	1021	Q9BX69
ERLNKSHRHQGLGGT	CASC3	276	O15234
GRAHGELHEQFKRKT	DOCK7	1951	Q96N67
RNHGVTAHLKGHKRL	DMRTC2	46	Q8IXT2
RNHGVVSALKGHKRF	DMRTA1	101	Q5VZB9
GESIKAAGKGRNNHR	GON4L	1576	Q3T8J9
LAKRGHFNRISHGLQ	DLD	11	P09622
KSKHGADEKRLHFGN	EPHA3	571	P29320
LRKVQLHHGGNKGQR	RALGDS	81	Q12967
SKGLIVKGRSHLNHE	ME3	371	Q16798
HQQGKTAAHVGIRDR	ITIH6	111	Q6UXX5
GVKHHNLEGLRKRIA	IQUB	551	Q8NA54
HRVRFQSHGLEGLNK	ASNSD1	506	Q9NWL6
KGKRSSEHVHSQGRV	EMC1	711	Q8N766
VRKRRRNGSKEGNHH	FAM104B	6	Q5XKR9
QEKRHREAHGENSGR	GJB5	101	O95377
TKHRRKGSHGLEIFQ	DKK1	221	O94907
IHRFTNGGKEKRVAH	NDUFA1	26	O15239
QEHGHSKEQGSRRRQ	PURG	136	Q9UJV8
GLHAKHIRAEAGGKR	PLEKHM1	61	Q9Y4G2
HIRAEAGGKRKKSAH	PLEKHM1	66	Q9Y4G2
RKHRGHSESPEKNGA	SNX29P2	211	Q8IUI4
ASDRRQKGQHHERTG	TMEM132C	821	Q8N3T6
LESGLGHQKRLARHQ	SYNE4	301	Q8N205
GQHGTDAERRHKKLP	ARHGAP17	56	Q68EM7
TRAVNKIHAFGKRGN	PLEKHA4	31	Q9H4M7
TGHNRQLGDVKHLLK	SMG1	3416	Q96Q15
QRAGKSLGQKRHHES	SHOC1	1386	Q5VXU9
AAEARAIKNGKGLHS	SND1	481	Q7KZF4
HRKQAASQEGRQKHA	MUTYH	26	Q9UIF7
AGRNKHGRKHELLTK	PIAS1	26	O75925
GGRISHQSQDKKIHV	PHPT1	76	Q9NRX4
LVKAARRGSQVGHKN	RRP12	1276	Q5JTH9
GLSSDRHKKRAGQNA	SMCR8	696	Q8TEV9
HGDLRKIHKAASRGQ	ANKRD30BL	36	A7E2S9
LIHRGAHIDVRNKKG	ANKHD1	1311	Q8IWZ3
GAKERAHQQKKHSGF	CHGA	86	P10645
KAHHAAGQSVRSGRL	CLASP2	381	O75122
KAFKGRSGLVQHQRA	ZNF837	426	Q96EG3
SNLNEHRKRHGGRAA	ZNF837	516	Q96EG3
VDQAHKSGVRHGDIK	PIK3R4	136	Q99570
AGNAARKNHLEGKAA	PAICS	41	P22234
GKNGDGRRRSAKDHH	TXNRD1	21	Q16881
GKGFTEKSHLNVHRR	ZNF615	546	Q8N8J6
TKSGLNVHQRKHTGE	ZNF615	691	Q8N8J6
GNLANLKRHGRIHSG	ZNF513	426	Q8N8E2
GKAFSDHIGLNQHRR	ZFP28	511	Q8NHY6
KTQGGHEHRQEDRLK	ZCWPW1	216	Q9H0M4
KSNLEGHRRIHTGEK	ZNF761	646	Q86XN6
QQNKAHKGGRHRGRG	TSR1	11	Q2NL82
SNSNRHKIRHTGEKG	ZNF676	126	Q8N7Q3
HKNQGRNLRSHTGER	ZNF791	56	Q3KP31
KCGKAFRRGHQLTVH	ZNF573	306	Q86YE8
KSNLSKHQRVHTGEG	ZSCAN21	456	Q9Y5A6
ALSKLKIHQRGHTGE	ZNF668	151	Q96K58
TGRSQKKREHGDHAD	RGS12	906	O14924
RNNSHAKKGRGHVQP	RPS26P11	6	Q5JNZ5
HGHGRQERSTKEKQS	SLC39A7	261	Q92504
KPQGQGHSRRDRHKA	STOX1	421	Q6ZVD7
KGNLNVHQRTHSGEK	ZSCAN5B	451	A6NJL1
GKSFGQKGNLVHHQR	ZNF587	386	Q96SQ5
GNLKRHIECTHGGKR	ZBTB41	531	Q5SVQ8
QVIGHRKLGHFRSQD	SUGP2	121	Q8IX01
FHAQAKGKNVRLDGH	NEURL1B	41	A8MQ27
ACGRGFSQKQHLLKH	ZNF775	506	Q96BV0
TTLRKLRKHQEAHGG	ZBTB4	736	Q9P1Z0
EKAGVGKLDHTNHRR	SLC4A5	6	Q9BY07
QGKAKHLRLSLNGHG	SH2B2	461	O14492
GSNLRTHQRLHTGEK	ZNF229	696	Q9UJW7
GSRLIQHENIHSGKK	ZNF582	211	Q96NG8
LRGHLQERHAQSKAG	ZNF469	3131	Q96JG9
QHTNDKKRSGHPRQD	WDR62	766	O43379
SGNLKRHLRIHSGEK	ZBTB17	486	Q13105
RKDKHDLLQGHQNGS	ZNF608	211	Q9ULD9
KSGLNLHQRVHTGER	ZNF230	376	Q9UIE0
NRNSGLHQRVHTGEK	ZNF233	436	A6NK53
NAGLKVHRRLHTGEK	ZFP62	461	Q8NB50
KGHLIQHQRTHTGEK	ZNF510	416	Q9Y2H8
LKNHMRTHNGKSGAR	ZNF217	171	O75362
RGNLSGNSHKHKGEA	PNISR	646	Q8TF01
GNSHKHKGEAKEQER	PNISR	651	Q8TF01
KAFGQKSQLRGHHRI	ZNF782	541	Q6ZMW2
KSQLRGHHRIHTGEK	ZNF782	546	Q6ZMW2
LRKHQRNHAAGAKTP	ZNF746	581	Q6NUN9
HHRFVIGKNGEKLQD	HDLBP	161	Q00341
FHRHLIGKSGANINR	HDLBP	446	Q00341
HRKAGTKNLLEIHGS	SIRT5	146	Q9NXA8
HGRRQHLAVSHEKGK	UBR4	1906	Q5T4S7
RNIAKRHDEGHKGPR	SULF1	571	Q8IWU6
GKQLSEHQRIHTGEK	ZNF571	431	Q7Z3V5
KGSKQDAAGHIERHA	ZNF106	1861	Q9H2Y7
RGDLGRLKKQKDHHN	TGFB3	261	P10600
SHGRDNSRFIKKQGL	XYLT2	356	Q9H1B5
RSDHRHAGNKPIKDQ	ZNF816	141	Q0VGE8
GKCFHQKGSLIRHQQ	ZNF776	466	Q68DI1
KLGHGTIRQAKAGNH	MYO7B	601	Q6PIF6
REAGKRNIHRKTGHD	MYO9A	716	B2RTY4
GQQHRHAAGEKRTKE	MYO9B	1461	Q13459
RKQLGHHIGARNIED	NEB	2556	P20929