Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 LRP6 SORL1

7.60e-0616493GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 LRP6 SORL1

1.79e-0521493GO:0030228
DomainLdl_recept_b

LRP2 LRP6 LRP5L SORL1

4.84e-0814514PF00058
DomainLDLRB

LRP2 LRP6 LRP5L SORL1

4.84e-0814514PS51120
DomainLY

LRP2 LRP6 LRP5L SORL1

6.58e-0815514SM00135
DomainLDLR_classB_rpt

LRP2 LRP6 LRP5L SORL1

6.58e-0815514IPR000033
Domain-

LRP2 LRP6 LRP5L SORL1

3.78e-06395142.120.10.30
DomainTMEM183

TMEM183A TMEM183BP

7.31e-062512IPR026509
Domain6-blade_b-propeller_TolB-like

LRP2 LRP6 LRP5L SORL1

7.39e-0646514IPR011042
DomainLDLR_class-A_CS

LRP2 LRP6 SORL1

1.76e-0440513IPR023415
DomainLdl_recept_a

LRP2 LRP6 SORL1

2.51e-0445513PF00057
Domain-

LRP2 LRP6 SORL1

2.68e-04465134.10.400.10
DomainLDLRA_1

LRP2 LRP6 SORL1

3.04e-0448513PS01209
DomainLDrepeatLR_classA_rpt

LRP2 LRP6 SORL1

3.23e-0449513IPR002172
DomainLDLa

LRP2 LRP6 SORL1

3.23e-0449513SM00192
DomainLDLRA_2

LRP2 LRP6 SORL1

3.23e-0449513PS50068
DomainTIL_dom

LRP2 MUC5B

6.51e-0414512IPR002919
DomainEGF_3

TLL1 LRP2 LRP6 SORL1

3.84e-03235514PS50026
DomainEGF

TLL1 LRP2 LRP6 SORL1

3.84e-03235514SM00181
DomainEGF-like_dom

TLL1 LRP2 LRP6 SORL1

4.72e-03249514IPR000742
DomainEGF

TLL1 LRP2 LRP6

4.93e-03126513PF00008
DomainEGF-like_CS

TLL1 LRP2 LRP6 SORL1

5.57e-03261514IPR013032
DomainEGF_2

TLL1 LRP2 LRP6 SORL1

5.87e-03265514PS01186
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

2.11e-06251216644869
Pubmed

Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.

GPR37 LRP6

2.11e-06251228341812
Pubmed

Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.

SLC24A4 SORL1

2.10e-05551225365775
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 SORL1

2.10e-05551219047013
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SIAE FAP PIGK TLL1 EDEM2 LRP6 B3GALT6 CLCC1 SORL1

5.58e-05120151935696571
Pubmed

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.

SLC24A4 HERC2

5.87e-05851218483556
Pubmed

Genetic determinants of hair, eye and skin pigmentation in Europeans.

SLC24A4 HERC2

9.42e-051051217952075
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP6

1.15e-041151224639464
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 LRP6

1.15e-041151223968836
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP2 LRP6

1.90e-041451217389516
Pubmed

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

SLC24A4 HERC2

2.19e-041551223548203
Pubmed

Defining the membrane proteome of NK cells.

EPRS1 NUP107 PIGK HELZ2 B3GALT6 NUP188 HERC2 CLCC1

2.79e-04116851819946888
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP2 LRP6

4.35e-042151221337463
Pubmed

Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.

ADRA2B LRP2

4.35e-04215129616220
Pubmed

Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.

LRP2 MUC5B

4.78e-042251212768436
Pubmed

UPF2 is a critical regulator of liver development, function and regeneration.

TMEM183A TMEM183BP

5.70e-042451220657840
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

PIEZO2 SLC24A4

6.19e-042551235681537
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

NUP107 NUP188

8.93e-043051224315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

NUP107 NUP188

8.93e-043051227016207
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

ASPM SORL1

9.54e-043151227798109
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EPRS1 SIAE TMEM183A POLG LRP2 TMEM183BP NUP188

9.81e-04108451711544199
Pubmed

The layered structure of human mitochondrial DNA nucleoids.

POLG POLDIP2

1.02e-033251218063578
Pubmed

Human transcription factor protein interaction networks.

PCF11 NUP107 KAT8 LRP2 LRP6 POLDIP2 HERC2 SORL1

1.05e-03142951835140242
Pubmed

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.

NUP188 CLCC1

1.08e-033351225582440
Pubmed

Web-based, participant-driven studies yield novel genetic associations for common traits.

SLC24A4 HERC2

1.15e-033451220585627
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 NUP107 ASPM LRP2 NUP188 POLDIP2 SORL1

1.16e-03111651731753913
Pubmed

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

SLC24A4 SORL1

1.36e-033751224162737
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PALD1 NUP107 POLG LRP2 NUP188 POLDIP2 HERC2 CLCC1

1.41e-03149651832877691
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP107 NUP188

1.43e-033851212791264
InteractionSOST interactions

LRP2 LRP6 HERC2 SORL1

1.66e-0635504int:SOST
Cytoband12p13.2

CLEC9A LRP6

1.16e-034551212p13.2
CytobandEnsembl 112 genes in cytogenetic band chr12q15

NUP107 BEST3

1.79e-0356512chr12q15
GeneFamilyLow density lipoprotein receptors

LRP2 LRP6

1.92e-0413292634
GeneFamilyNucleoporins

NUP107 NUP188

1.20e-03322921051
GeneFamilyG protein-coupled receptors, Class A orphans

GPR37 GPR173

6.92e-0378292262
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PALD1 PIEZO2 TLL1 KCNN3 ATP4B

1.40e-06168515dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

PALD1 PIEZO2 TLL1 KCNN3 ATP4B

1.40e-06168515a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP ADRA2B SLC24A4 LYZL4 TLL1

1.76e-06176515e788c7e0b2bfde31fddbf9e04d07140f8b964857
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOPAZ1 CPT1C BSPH1 ASPM

1.69e-05134514e0f3ca643c206929203d80095663a5eac98ac088
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNN3 BEST3 MUC5B CHST1

2.56e-05149514c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNN3 BEST3 MUC5B CHST1

2.56e-05149514a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGMS2 TOPAZ1 GPR37 SORL1

3.72e-051645148e6dbddacd56a07769163813e3ebfad13302bb62
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIAE SGMS2 BEST3 MUC5B

3.90e-0516651460060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIAE SGMS2 BEST3 MUC5B

3.90e-05166514ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIAE SGMS2 BEST3 MUC5B

3.90e-051665144586d6725403f879fc96f67be579022587ce1906
ToppCell356C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A SLC24A4 KIAA1958 LRP6

3.90e-05166514971ee6602a1e751f453f9d823295e63dadce62bf
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM129 GPR37 CPT1C CHST1

4.28e-05170514d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP ADRA2B SLC24A4 CHST1

4.69e-051745140df738309b7b6e77675ea74e7a87e66601b0073d
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM129 GPR37 CPT1C CHST1

4.90e-05176514c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM129 GPR37 CPT1C CHST1

4.90e-05176514cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP SLC24A4 TLL1 CHST1

4.90e-05176514de746cdf2c777eec88cb03863e128e97ad6e8fb0
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAP CPT1C HELZ2 CHST1

5.01e-0517751430f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PALD1 PIEZO2 TLL1 KCNN3

5.12e-05178514c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

CLEC9A SLC24A4 KCNN3 LRP6

5.12e-051785140667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP SLC24A4 LYZL4 CHST1

5.35e-051805147a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP SLC24A4 LYZL4 CHST1

5.58e-051825141647367b75b4b107af06bb934394168230cfd7c2
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLL1 KCNN3 B3GALT6 CHST1

5.95e-05185514bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellControl-Myeloid-cDC1|World / Disease state, Lineage and Cell class

PALD1 ADRA2B CLEC9A SLC24A4

6.07e-051865143de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

PALD1 ADRA2B CLEC9A SLC24A4

6.07e-05186514b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PALD1 ADRA2B CLEC9A SLC24A4

6.33e-05188514d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 PIEZO2 TLL1 KCNN3

6.33e-051885142db80767903703e7e0a1a37c598f7877a909ee94
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 PIEZO2 TLL1 KCNN3

6.33e-05188514c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

PALD1 PIEZO2 TLL1 KCNN3

6.46e-05189514c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 PIEZO2 TLL1 KCNN3

6.59e-051905146e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PALD1 PIEZO2 TLL1 KCNN3

6.87e-05192514cbe57cda44232b183821ac633b60a2668265e616
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPRS1 FAP PIEZO2 KCNN3

7.01e-051935147cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 EDEM2 ASPM KCNN3

7.01e-051935141f50823bd7ef00500d9d81f0f5c2f6c940c4b1a6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 PIGK EDEM2 KCNN3

7.01e-0519351443ffa8ecc72bebcd204279db2bde98ae48d97f90
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 EDEM2 ASPM KCNN3

7.01e-05193514b9c00df1b216eaa4283315713f1c9ef552d3d435
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 PIEZO2 TLL1 KCNN3

7.44e-0519651409a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 PIEZO2 TLL1 KCNN3

7.44e-05196514e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 CLEC9A SLC24A4 TOPAZ1

7.58e-051975147e15ed71881105dee5c7ffc052063ecc8ac0b36e
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 PIEZO2 TLL1 KCNN3

7.73e-05198514b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 PIEZO2 TLL1 KCNN3

7.73e-05198514fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 TLL1 KCNN3 CHST1

7.73e-05198514c77421898cc84ae2e8cc335087198dd05f13bfa5
ToppCellNeuronal-Excitatory-eH(THEMIS)-CRABP1--|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAP ADRA2B SLC24A4 LYZL4

8.04e-0520051473b7e395398fdc9aa5adb3ade675ae0168d7f46c
ToppCellNeuronal-Excitatory-eH(THEMIS)-CRABP1---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAP ADRA2B SLC24A4 LYZL4

8.04e-05200514c9113e7a9624499db3e66c01462159e8e8781cc4
ToppCellNeuronal-Excitatory-eH(THEMIS)-CRABP1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAP ADRA2B SLC24A4 LYZL4

8.04e-05200514473e85930f433e392956a7a10ea5d09fdc2a35b1
ToppCellNeuronal-Excitatory-eH(THEMIS)-CRABP1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAP ADRA2B SLC24A4 LYZL4

8.04e-05200514a737c4f535723e389ba4b957ae1fdc5162d3d951
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1|Striatum / BrainAtlas - Mouse McCarroll V32

PIEZO2 GPR37 SGK2

3.18e-04116513c19974992b315fb873664fe3f5077ff8e907e30c
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-|Striatum / BrainAtlas - Mouse McCarroll V32

TTLL6 TOPAZ1 LRP2

3.26e-0411751326dec09112532f351fb7a2202bae84c365707b40
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)|Striatum / BrainAtlas - Mouse McCarroll V32

TTLL6 TOPAZ1 LRP2

3.26e-04117513db053c874e6739052dff1f91643e51b306236237
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--|Striatum / BrainAtlas - Mouse McCarroll V32

TTLL6 TOPAZ1 LRP2

3.26e-0411751380780223502d18f0d86a29ff3cb74aa8235103c7
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL|Striatum / BrainAtlas - Mouse McCarroll V32

TTLL6 TOPAZ1 LRP2

3.26e-0411751340889f4a387846abbf54469cc4faf616bfe348d0
ToppCellStriatum-Macroglia-CSF_related|Striatum / BrainAtlas - Mouse McCarroll V32

TTLL6 TOPAZ1 LRP2

3.26e-04117513e12e37e393257db85f7f5c13454095c44f59d374
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_dendritic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLEC9A GPR173 KIAA1958

3.86e-0412451368ba24ce0ab837f3baa40884bed2ed104e16d041
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HELZ2 LRP5L TMEM229B

4.85e-041345139e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PALD1 ASPM KCNN3

5.97e-041445130fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SGMS2 CLEC9A SLC24A4

6.10e-04145513f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

ADRA2B SLC24A4 TMEM121B

6.22e-041465137b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellCiliated_cells-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KCNN3 MUC5B ATP4B

6.22e-0414651320f080318e9cbfd9b8b90a5e9f704d6d85b969ee
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMEM121B CHST1 SORL1

6.34e-041475138f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PALD1 TLL1 KCNN3

6.47e-04148513f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SGMS2 CLEC9A SLC24A4

6.73e-04150513f4aed24b79e1be38abc7a1120256821601893d6d
ToppCellnormal_Lung-Myeloid_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

ADRA2B CLEC9A TMEM121B

6.86e-0415151323b6cf9a36ad0e937f69c75921bddd305a9a526c
ToppCell390C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B CLEC9A SORL1

6.99e-04152513ebce79e106bf1d84241f8dd3496ff1771f9666be
ToppCell390C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B CLEC9A SORL1

6.99e-041525134a749d1b6d35fd55a8c42d7bd04b6ff5b11ce781
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP107 TMEM121B B3GALT6

7.26e-0415451375eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 CLEC9A SLC24A4

7.26e-041545135967a0a33456d5930fc492a700ebb015ac050abb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNN3 CLCC1

7.40e-04155513881422c57d230c0e2e5f9098ab888caa94ca61aa
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 CLEC9A SLC24A4

7.40e-04155513fab281db4c275d51240b122be78713c839ba5a95
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

ADRA2B GPR173 SORL1

7.40e-041555134b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PALD1 PIEZO2 GPR173

7.54e-041565139a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

LRP2 LRP5L SORL1

7.54e-0415651325b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CPT1C TLL1 HELZ2

7.68e-041575134183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAP PIEZO2 CPT1C

7.68e-04157513f147e24f2ece82e1c54750868954d09b3c461804
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR37 MUC5B LRP5L

7.68e-04157513c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CPT1C TLL1 HELZ2

7.82e-04158513de65af8d3b8514b17978155f31975e2347b75251
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAP PIEZO2 CPT1C

7.82e-04158513e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLL1 LRP2 MUC5B

8.11e-04160513c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC24A4 TMEM121B CHST1

8.11e-04160513f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLL1 LRP2 MUC5B

8.11e-0416051325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PIEZO2 KCNN3

8.26e-04161513fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAP ASPM B3GALT6

8.26e-04161513a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PIEZO2 KCNN3

8.26e-04161513c53c461fc721a7960cef86662f49e2a495520701
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAP ASPM B3GALT6

8.26e-0416151308920a716f6ec62538e361211455a30ad726d7be
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC24A4 TMEM121B SORL1

8.26e-04161513ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

PALD1 CLEC9A SORL1

8.41e-04162513810881210e015c788814e4fe8d7a24c929cf2621
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM121B MUC5B SORL1

8.41e-04162513dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNN3 CLCC1

8.41e-041625138278dccdb139396ede34b83b02ebce837f2489d6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PIEZO2 KCNN3

8.41e-041625132ac02523348660e514d464f8f2434ee0c312d784
ToppCelldroplet-Lung-LUNG-30m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM121B MUC5B SORL1

8.41e-041625132a4e09545e9874519f0f56e81065104987d81cd6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BSPH1 ASPM ATP4B

8.56e-041635133f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCelllymphoid-B_cell-pro-B|lymphoid / Lineage, cell class and subclass

PIEZO2 GPR173 BEST3

8.86e-041655138126c2f7810fc6e09b18783aadf6434ae12b0514
ToppCellEndothelial-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 GPR37 TLL1

8.86e-0416551310087d8bd2985906ef19547fe77eb178ae5e1638
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

PALD1 CLEC9A SLC24A4

9.02e-041665130590e404f45afce90e20f93f90a3def83949c66b
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B GPR37 BEST3

9.18e-0416751349d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

PALD1 PIEZO2 KCNN3

9.18e-0416751397d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

LYZL4 TLL1 MUC5B

9.18e-041675136efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B GPR37 BEST3

9.18e-041675137ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B GPR37 BEST3

9.18e-041675135e3588eee73693a996bb4846427cf0038ceafbca
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMEM121B CHST1 SORL1

9.34e-041685136db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellfacs-Kidney|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2B LRP2 SGK2

9.34e-04168513d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 TLL1 KCNN3

9.34e-041685134977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLEC9A SLC24A4 TMEM229B

9.50e-041695134de0c60f3c163b7823f739ebda4e0afc68346628
Diseasesuntan

PIEZO2 SLC24A4 EDEM2 HERC2

2.63e-05103494EFO_0004279
Diseasepigmentation disease (is_implicated_in)

SLC24A4 HERC2

1.47e-0411492DOID:10123 (is_implicated_in)
Diseasehair colour measurement, hair morphology measurement

SLC24A4 HERC2

1.76e-0412492EFO_0007821, EFO_0007822
Diseasefamily history of Alzheimer’s disease

SLC24A4 KAT8 SORL1

2.27e-0471493EFO_0009268
Diseasecorneal resistance factor

TTLL6 KAT8 LRP6 CHST1 HERC2

8.95e-04451495EFO_0010067
DiseaseAlzheimer disease, family history of Alzheimer’s disease

SLC24A4 KAT8 SORL1

1.03e-03119493EFO_0009268, MONDO_0004975

Protein segments in the cluster

PeptideGeneStartEntry
RYRSWCSLLFGYDWV

BEST3

216

Q8N1M1
GRWREAAWQLCDYYL

B3GALT6

196

Q96L58
WYSSYGFTRRWNCIL

ARSH

211

Q5FYA8
LWLSCYGSALWRYST

CATSPERE

11

Q5SY80
ANELLGYWYFRRTWC

ADRA2B

71

P18089
GRTLSRWVWISLYYV

ATP4B

31

P51164
IQAWYRCWRAHKEYL

ASPM

2961

Q8IZT6
TVCVREVCRWSSWYN

MUC5B

1331

Q9HC84
VRLTWWAVCRDSVYY

SLC24A4

196

Q8NFF2
VCDTWEDTVWAYFRV

NUP107

441

P57740
SVWQRALWSLERYFY

PALD1

416

Q9ULE6
QNSHVYWWRYCIRLE

POLDIP2

256

Q9Y2S7
YWWRYCIRLENLDSD

POLDIP2

261

Q9Y2S7
TWSRYCQYSDTLARW

LYZL4

126

Q96KX0
WAWFRRYCMASRVAV

HERC2

3871

O95714
YRSYWSWVLLEILRD

KAT8

361

Q9H7Z6
AIRNYTRFDDWYLWV

EDEM2

286

Q9BV94
WIIAAWTVRVCERYH

KCNN3

471

Q9UGI6
YSWCSQRLVEERYSW

POLG

221

P54098
YWTDDEVWAIRRAYL

LRP5L

6

A4QPB2
YQDYIYWTDWSRRSI

LRP6

841

O75581
AIDWAASRLYWVDAY

LRP2

876

P98164
WAVLVCTSRFWFNYR

PIGK

46

Q92643
HRRWYYSLTDWIEFE

PCF11

1381

O94913
YVSDWWEEFVYLRSR

CPT1C

231

Q8TCG5
IYVLALTYDSARLWW

GPR37

431

O15354
VFPFWYRRLIYWECT

BSPH1

91

Q075Z2
LLLWSPYIVACYWRV

GPR173

296

Q9NS66
DWYTWATSPIRRYLD

HELZ2

1666

Q9BYK8
QWIYWTDAYLECIER

SORL1

931

Q92673
CYILRPWAYAIWEAI

EPRS1

1046

P07814
GLFVRYLSDYWCWDL

TMC3

531

Q7Z5M5
YDRAVDWWCLGAVLY

SGK2

211

Q9HBY8
LCWYDYIEVRDGYWR

TLL1

401

O43897
DLYLIAVTDLYWCSW

TMEM121B

216

Q9BXQ6
RCLIYTLWTYLWEFT

TMEM229B

76

Q8NBD8
WTVTCTAAFWTRLYR

TMEM183BP

161

Q1AE95
VALRYAWTTWPCEYK

SIAE

476

Q9HAT2
DVIIAYYITTRLFWW

SGMS2

276

Q8NHU3
TFRDTYRLWRLWYGT

CHST1

246

O43916
RESCYYVSEIWSIWH

CLEC9A

121

Q6UXN8
VVLVATELWTYVRWY

CLCC1

196

Q96S66
TELWTYVRWYTQLRR

CLCC1

201

Q96S66
YYFSWLTWVTDERVC

FAP

291

Q12884
WTVTCTAAFWTRLYR

TMEM183A

161

Q8IXX5
IFERWECTTYWYIFV

TMEM107

101

Q6UX40
LFCVALYQVHYEWWR

PIEZO2

716

Q9H5I5
SILRYWDWLIAYNVF

PIEZO2

1341

Q9H5I5
KWDDDYVRYWFTCTT

ZBED8

6

Q8IZ13
RAYLVRWEYSYSSWT

NUP188

526

Q5SRE5
WTLYWTDYSVSLERV

TTLL6

91

Q8N841
KRTWPYYSCARISAW

TOPAZ1

491

Q8N9V7
CLTYEQITGWWYSVR

ZSWIM8

376

A7E2V4
IACILIYYWSRDRWA

TMEM129

106

A0AVI4
TKATRYALNVWRYWC

KIAA1958

421

Q8N8K9