Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF4599	SPATA31A7 SPATA31A6 SPATA31C1 SPATA31A3 SPATA31A5	1.50e-07	12	217	5	PF15371
Domain	DUF4599	SPATA31A7 SPATA31A6 SPATA31C1 SPATA31A3 SPATA31A5	1.50e-07	12	217	5	IPR027970
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A7 SPATA31A6 SPATA31C1 SPATA31A3 SPATA31A5	6.33e-11	6	224	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A7 SPATA31A6 SPATA31C1 SPATA31A3 SPATA31A5	6.33e-11	6	224	5	25930072
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	IQGAP2 MYO5A DOCK11 ADGRB3 ZMYM2 EDC4 TENM2 GATAD2B NF1 MDN1 FAM120A FAM120C SHANK1 RGPD2 SYNE1 KCNAB2 DYRK1A CCT4 CIT WDR45 MTOR N4BP2 KIAA1217 PDE4DIP BRD7 CNOT1 TP53BP1	1.77e-10	963	224	27	28671696
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BCL9L SYN3 MAP1B MYO5A VPS45 ADGRB3 EDC4 TENM2 GATAD2B STIM1 NF1 KCNF1 FAM120C SHANK1 RGPD2 USP24 APBA1 KCNAB2 CCT4 LDHA CIT TRAP1 KIAA1217 PDE4DIP TENM1 MRPS9 CNOT1 TP53BP1	1.51e-09	1139	224	28	36417873
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A7 SPATA31A6 SPATA31C1 SPATA31A3 SPATA31A5	4.08e-07	24	224	5	32212159
Pubmed	A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation.	EDC4 RC3H2 CNOT1	1.05e-06	4	224	3	31636267
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 GGA2 CAND2 PIEZO1 ADGRB3 KDM3B NRXN3 SUPT6H CELSR3 SETBP1 AUTS2 SETD7 IGSF1 CNOT1 NIN	2.06e-06	529	224	15	14621295
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SCFD2 USP34 CAND2 MAP1B IQGAP2 VPS45 BCL3 EDC4 ITPR2 NOP9 MDN1 FAM120A POMP COG4 ATF7 PIGS BAG5 CCT4 LDHA TRAP1 POLR3B MTOR TMEM209 MRPS9 TRAPPC14 CNOT1	2.35e-06	1440	224	26	30833792
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	IQGAP2 USP11 ZMYM2 TSPYL1 EDC4 GATAD2B CDC45 SUPT6H PKP2 PIP5K1A CLUH TRAP1 POLR3B SETD7 CNOT1	4.10e-06	560	224	15	35241646
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 MAP1B MYO5A USP11 EDC4 NF1 MDN1 FAM120A SUPT6H CLUH PUF60 USP24 MTOR CNOT1 CPSF3 TP53BP1	6.01e-06	653	224	16	22586326
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SYN3 MAP1B IQGAP2 MYO5A VPS45 EDC4 ITPR2 NF1 FAM120A FAM120C PTPRZ1 HSDL1 SHANK1 SYNE1 KCNAB2 DYRK1A CCT4 LDHA CIT SLC25A12 KIAA1217 PDE4DIP MRPS9 CNOT1 DNPEP	6.59e-06	1431	224	25	37142655
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MYO5A CEP85L NAGLU STIM1 MDN1 IMP4 PKP2 RBMS1 PIGS BAG5 CIT MTOR PDE4DIP MRPS9 CPSF3 DNPEP NIN	9.10e-06	754	224	17	33060197
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 MYO5A CEP85L USP11 VPS45 ADGRB3 ZMYM2 RYR3 JAK1 FAM120A SMPD3 COG4 SHANK1 SYNE1 APBA1 KCNAB2 DYRK1A CIT SPRYD7 POLR3B CELSR3 PDE4DIP MRPS9	1.07e-05	1285	224	23	35914814
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MAP1B IQGAP2 USP11 ZMYM2 GATAD2B NOP9 MDN1 FAM120A ZBTB40 ATF7 UBR2 PUF60 DYRK1A DEPDC1 NFATC2IP SETD7 NHEJ1 TP53BP1	1.28e-05	857	224	18	25609649
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP1B DOCK11 CEP85L KDM3B EDC4 STIM1 ZCCHC14 NF1 MDN1 PKP2 DYRK1A PABIR2 MTOR N4BP2 KIAA1217 TRAPPC14 PLK4 EDRF1	1.37e-05	861	224	18	36931259
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	PSG11 PIEZO1 SDCCAG8 KDM3B TENM2 ZBTB40 MMP12 AFF2 MUC16 SLC39A12 DPH5 PDE4DIP TMEM209 TENM1	1.59e-05	552	224	14	10737800
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 ADGRB3 KDM3B ZCCHC14 ZBTB40 SYNE1 SETBP1 AUTS2 NIN	1.69e-05	225	224	9	12168954
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DOCK11 USP11 ITPR2 NF1 SUPT6H IMP4 SMG9 PKP2 DYRK1A BRD7 TMEM209 TP53BP1	3.21e-05	440	224	12	34244565
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KBTBD3 CDH26 TP53INP1 MAP1B MYO5A VPS45 SDCCAG8 NDUFB8 ZNF440 FAM120A FAM120C SUPT6H TOX3 PIP5K1A ATF7 UBR2 DDR1 ATP10A DNAH1 PARP10 KIAA1217 SETBP1 AUTS2 CNOT1	3.73e-05	1489	224	24	28611215
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	MAP1B TSPYL1 EDC4 NOP9 FAM120A IMP4 PKP2 PIP5K1A RC3H2 PUF60 RBMS1 CCT4 MRPS9 TRAPPC14 CNOT1	3.83e-05	678	224	15	30209976
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAND2 MAP1B IQGAP2 MYO5A USP11 ZMYM2 JAK1 NF1 DYRK1A CPSF3	3.97e-05	313	224	10	38270169
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCFD2 USP11 NDUFB8 ITPR2 CDC45 STIM1 MDN1 FAM120A ADSL IMP4 TOX3 MALSU1 HSDL1 CLUH RBMS1 SYNE1 BAG5 CCT4 TRAP1 SLC25A12 KIAA1217 BRD7 TMEM209 MRPS9	4.02e-05	1496	224	24	32877691
Pubmed	TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.	TASOR CNOT1	4.13e-05	2	224	2	35013187
Pubmed	Structure-function studies on the biosynthesis and bioactivity of the precursor convertase PC2 and the formation of the PC2/7B2 complex.	PCSK2 CD86	4.13e-05	2	224	2	7720862
Pubmed	Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis.	LDHA MTOR	4.13e-05	2	224	2	34293399
Pubmed	MTOR Suppresses Cigarette Smoke-Induced Airway Inflammation and MMP12 Expression in Macrophage in Chronic Obstructive Pulmonary Disease.	MMP12 MTOR	4.13e-05	2	224	2	38288346
Pubmed	Werner syndrome protein positively regulates XRCC4-like factor transcription.	WRN NHEJ1	4.13e-05	2	224	2	24626809
Pubmed	The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells.	LDHA MTOR	4.13e-05	2	224	2	30138330
Pubmed	NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation.	ALKBH1 NSUN3	4.13e-05	2	224	2	27497299
Pubmed	Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.	NF1 MTOR	4.13e-05	2	224	2	21748792
Pubmed	Relationship of plasma apolipoprotein M with proprotein convertase subtilisin-kexin type 9 levels in non-diabetic subjects.	APOM PCSK9	4.13e-05	2	224	2	21122852
Pubmed	Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance.	MYO5A RYR3	4.13e-05	2	224	2	27134178
Pubmed	mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.	BCL3 MTOR	4.13e-05	2	224	2	17110454
Pubmed	A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.	CEP85L ITPR2	4.13e-05	2	224	2	22010048
Pubmed	Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.	NHEJ1 TP53BP1	4.13e-05	2	224	2	22355127
Pubmed	Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.	PCSK2 PCSK9	4.13e-05	2	224	2	16893422
Pubmed	Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing.	GCNT1 CHST4	4.13e-05	2	224	2	14593101
Pubmed	Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair.	NHEJ1 TP53BP1	4.13e-05	2	224	2	22308489
Pubmed	Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels.	PIEZO1 SMPD3	4.13e-05	2	224	2	33027663
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	KMT2B ZMYM2 GATAD2B SUPT6H RGPD2 KIAA1217 CNOT1	4.76e-05	146	224	7	23892456
Pubmed	Control of TurboID-dependent biotinylation intensity in proximity ligation screens.	ATP8A2 ITPR2 STIM1 SLC38A10 POMP CIT	4.81e-05	100	224	6	36966971
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CAND2 IQGAP2 VPS45 SDCCAG8 STIM1 TMEM161A NF1 POMP CLUH NPHP1 RBMS1 PIGS WRN DYRK1A PABIR2 ACTR1B TRAP1 MTOR CNOT1 EDRF1 TP53BP1 DNPEP	4.96e-05	1321	224	22	27173435
Pubmed	Human transcription factor protein interaction networks.	BCL9L KMT2B MYO5A USP11 ZMYM2 EDC4 GATAD2B FAM120A ZBTB40 DNAH10 RBMS1 BAG5 CCT4 CIT MIDN ZZZ3 BRD7 MRPS9 AUTS2 ELF2 CNOT1 RAI2 TP53BP1	5.58e-05	1429	224	23	35140242
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	IL10RB CAND2 MYO5A USP11 EDC4 NDUFB8 ZCCHC14 SLC38A10 NF1 MDN1 LNX2 USP24 PHTF2 LDHA CIT ZZZ3 MTOR DNAH17 BRD7 CPSF3 DNPEP	5.98e-05	1242	224	21	30973865
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	USP34 ADGRB3 ZCCHC14 NRXN3 ATP10A SUSD5	6.32e-05	105	224	6	9628581
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	USP34 ITPR2 JAK1 SUPT6H TASOR UBR2 USP24 SLC25A12	7.51e-05	212	224	8	33853758
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	ZMYM2 ZC3H12B ALKBH1 SUPT6H DNAH10 MANEA CCT4 DEPDC1 PPM1B	8.50e-05	277	224	9	30745168
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH10 DNAH1 DNAH17	9.11e-05	14	224	3	9373155
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	BCL9L KMT2B MYO5A VPS45 PIEZO1 ZMYM2 TSPYL1 EDC4 GATAD2B TMEM161A MDN1 FAM120C SUPT6H IMP4 TASOR RBMS1 SYNE1 WRN DYRK1A CCT4 CIT BRD7 EDRF1	1.11e-04	1497	224	23	31527615
Pubmed	Pleckstrin-2-promoted PPM1B degradation plays an important role in transforming growth factor-β-induced breast cancer cell invasion and metastasis.	PPM1B PLEK2	1.23e-04	3	224	2	36928924
Pubmed	MUC16-mediated activation of mTOR and c-Myc reprograms pancreatic cancer metabolism.	MUC16 MTOR	1.23e-04	3	224	2	26046375
Pubmed	Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway.	JAK1 MTOR	1.23e-04	3	224	2	21861134
Pubmed	Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.	DYRK1A PPM1B	1.23e-04	3	224	2	33380426
Pubmed	PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.	NHEJ1 TP53BP1	1.23e-04	3	224	2	28051062
Pubmed	Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes.	GCNT1 CHST4	1.23e-04	3	224	2	15319280
Pubmed	Elucidating the mechanism of IL-1β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway.	PIEZO1 MTOR	1.23e-04	3	224	2	38134572
Pubmed	De novo mutations in moderate or severe intellectual disability.	GATAD2B SETBP1	1.23e-04	3	224	2	25356899
Pubmed	The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.	USP11 MTOR	1.23e-04	3	224	2	34044068
Pubmed	Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.	PIEZO1 MTOR	1.23e-04	3	224	2	36112948
Pubmed	Phosphorylation of Munc18-1 by Dyrk1A regulates its interaction with Syntaxin 1 and X11α.	APBA1 DYRK1A	1.23e-04	3	224	2	22765017
Pubmed	hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity.	TIPIN WRN RFWD3	1.39e-04	16	224	3	24126761
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	MAP1B ATP8A2 SDCCAG8 NAGLU TUB GJA10 MYRF NPHP1	1.44e-04	233	224	8	32290105
Pubmed	Genome-wide meta-analysis identifies new susceptibility loci for migraine.	EYA1 ADARB2 TBXAS1 ATF7 SUGCT	1.53e-04	78	224	5	23793025
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	BCL9L DOCK11 TSPYL1 NF1 NYNRIN PKP2 LNX2 BAG5 TRAPPC14 CNOT1 NIN	1.65e-04	446	224	11	24255178
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 GGA2 ATP7A IQGAP2 VPS45 KDM3B STIM1 PKP2 TASOR AFF2 WRN MUC16 CCT4 LDHA MRPS9	1.73e-04	777	224	15	35844135
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	CDH26 MAP1B MYO5A GATAD2B KCNAB2 CCT4 LDHA ACTR1B TRAP1 SLC25A12 MTOR SETBP1 ATP1A4	2.16e-04	621	224	13	22794259
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	VPS45 TUB STIM1 TMEM161A NF1 PKP2 PIP5K1A EFNB3 SUSD5 SPRY4 TMEM209	2.45e-04	467	224	11	30194290
Pubmed	Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.	DYRK1A MANEA	2.46e-04	4	224	2	16733250
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM2 TENM1	2.46e-04	4	224	2	10225957
Pubmed	Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3.	BCL3 TNFRSF8	2.46e-04	4	224	2	16108830
Pubmed	Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.	MTOR TP53BP1	2.46e-04	4	224	2	19955088
Pubmed	Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.	KMT2B SETD7	2.46e-04	4	224	2	17166833
Pubmed	MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1.	NF1 MTOR	2.46e-04	4	224	2	24509877
Pubmed	p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.	NF1 MTOR	2.46e-04	4	224	2	29392777
Pubmed	LINC01234 promoted malignant behaviors of breast cancer cells via hsa-miR-30c-2-3p/CCT4/mTOR signaling pathway.	CCT4 MTOR	2.46e-04	4	224	2	38216268
Pubmed	Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination.	BCL3 N4BP2	2.46e-04	4	224	2	12730195
Pubmed	The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34.	FAM120A FAM120C	2.46e-04	4	224	2	14585507
Pubmed	Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: involvement of the Akt-mTOR signaling pathway.	LDHA MTOR	2.46e-04	4	224	2	25524555
Pubmed	PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.	STIM1 MTOR	2.46e-04	4	224	2	22031597
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM2 TENM1	2.46e-04	4	224	2	12000766
Pubmed	Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion.	CDC45 TIPIN	2.46e-04	4	224	2	20124417
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	MAP1B USP11 SUPT6H PKP2 BAG5 KIAA1217 MRPS9 CNOT1	2.52e-04	253	224	8	29911972
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	BCL9L EYA1 GATAD2B FAM120A SUPT6H TASOR RC3H2 N4BP2 BRD7 CNOT1 TP53BP1	2.54e-04	469	224	11	27634302
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SCFD2 ATP7A CAND2 MYO5A USP11 PIEZO1 NDUFB8 ITPR2 STIM1 MDN1 FAM120A SUPT6H PIP5K1A CLUH SYNE1 BAG5 N4BP2 TMEM209 MRPS9 EDRF1 TP53BP1 NIN	2.67e-04	1487	224	22	33957083
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	FBXL13 ATP7A CDC42SE1 GCNT1 ITPR2 NF1 MDN1 ADSL EVA1A COG4 ATF7 WRN PHTF2 NOX4 KMO MTOR PDE4DIP MYOM2 PLK4 TP53BP1	2.90e-04	1293	224	20	15342556
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	KMT2B ATP8A2 KDM3B ADAMTS15 PIP5K1A MMP12 RC3H2 DNAH10 USP24 PPM1B POLR3B DNAH17 PLK4 KLHL17	3.03e-04	730	224	14	34857952
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	VPS45 ADGRB3 TENM2 SHANK1 KCNAB2 CIT PDE4DIP	3.05e-04	197	224	7	36604605
Pubmed	Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.	TENM2 FRMD1 ATP10A TENM1 AUTS2	3.14e-04	91	224	5	22610502
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 KDM3B GATAD2B ITPR2 ZCCHC14 FAM120A SMG9 TASOR CLUH COG4 POLR3B N4BP2 TMEM209 CPSF3	3.16e-04	733	224	14	34672954
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 KMT2B PIEZO1 NAGLU KDM3B EDC4 ITPR2 ZCCHC14 SLC38A10 MDN1 MYRF PUF60 DYRK1A CIT CELSR3 MTOR ANKRD33B KLHL17	3.19e-04	1105	224	18	35748872
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	USP34 KMT2B ZMYM2 ITPR2 MDN1 FAM120A PKP2 LDHA	3.19e-04	262	224	8	36880596
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CEP85L SDCCAG8 ACTR1B PDE4DIP PLK4 NIN	3.82e-04	146	224	6	21399614
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 USP11 NF1 USP24 RFWD3 MTOR	3.97e-04	147	224	6	29576527
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	KDM3B ZMYM2 EDC4 GATAD2B ITPR2 JAK1 FAM120C IMP4 TP53BP1	3.97e-04	341	224	9	32971831
Pubmed	SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.	NHEJ1 TP53BP1	4.08e-04	5	224	2	35764636
Pubmed	NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways.	NOX4 MTOR	4.08e-04	5	224	2	25589557
Pubmed	IL-27 inhibits IFN-γ induced autophagy by concomitant induction of JAK/PI3 K/Akt/mTOR cascade and up-regulation of Mcl-1 in Mycobacterium tuberculosis H37Rv infected macrophages.	JAK1 MTOR	4.08e-04	5	224	2	25194337
Pubmed	Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 Axis.	NOX4 MTOR	4.08e-04	5	224	2	26565025
Pubmed	AROS-29 is involved in adaptive response to oxidative stress.	TMEM161A TRAP1	4.08e-04	5	224	2	16551573
Pubmed	Dyrk1a Mutations Cause Undergrowth of Cortical Pyramidal Neurons via Dysregulated Growth Factor Signaling.	DYRK1A MTOR	4.08e-04	5	224	2	33840455
Cytoband	4q28	ELF2 SETD7 PLK4	9.42e-06	9	224	3	4q28
GeneFamily	Dyneins, axonemal	DNAH10 DNAH1 DNAH17	2.68e-04	17	137	3	536
Coexpression	GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP	ZMYM2 ADSL TIPIN IMP4 CCT4 ZZZ3 NSUN3 STKLD1 NHEJ1 DNPEP	5.35e-06	193	218	10	M7244
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	GGA2 IQGAP2 MYO5A PIEZO1 NF1 TBXAS1 UBR2 SYNE1 AUTS2 CNOT1	6.70e-06	198	218	10	M6511
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	ATP7A MAP1B IQGAP2 DOCK11 ITPR2 FAM13C MUC16 SLC25A12 AUTS2	7.64e-07	199	223	9	8194777d367405a7840787e977854b5c07e3bd6b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 IQGAP2 EYA1 NRXN3 PTPRZ1 TOX3 PKP2 MUC16 KIAA1217	7.96e-07	200	223	9	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1B DOCK11 TENM2 AFF2 OLFML2B SYNE1 SUSD5 SPRY4 ATP1A4	7.96e-07	200	223	9	b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell	ASK428-Epithelial-Secretory\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	BCL3 ALKBH1 PTPRZ1 NYNRIN HSD17B13 SH2D3A CH25H CIT	2.36e-06	170	223	8	9e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A2 GCNT1 NRXN3 PKP2 SMPD3 CIT HMCN1 N4BP2	2.58e-06	172	223	8	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8A2 GCNT1 NRXN3 PKP2 SMPD3 CIT HMCN1 N4BP2	2.58e-06	172	223	8	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	PCSK2 IQGAP2 MYO5A ADGRB3 NRXN3 PTPRZ1 CIT KIAA1217	2.69e-06	173	223	8	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 RYR3 TOX3 PKP2 DDR1 AFF2 KMO TENM1	3.61e-06	180	223	8	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 TOX3 ADAMTS15 AFF2 KIAA1217 TENM1 PLCXD3	3.76e-06	181	223	8	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A PDE4DIP ANKRD33B	4.08e-06	183	223	8	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	MAP1B IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A PDE4DIP	4.08e-06	183	223	8	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A PDE4DIP ANKRD33B	4.08e-06	183	223	8	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A PDE4DIP ANKRD33B	4.25e-06	184	223	8	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 PTPRZ1 TOX3 AFF2 KIAA1217 TENM1 PLCXD3	4.79e-06	187	223	8	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	facs-Lung-24m-Hematologic-myeloid-leukocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCFD2 SYN3 HACE1 NPHP1 KCNAB2 PHTF2 MANEA TUBD1	4.98e-06	188	223	8	61b6047affa18c5e71210fcce449e2bbe7cf141b
ToppCell	facs-Lung-24m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCFD2 SYN3 HACE1 NPHP1 KCNAB2 PHTF2 MANEA TUBD1	4.98e-06	188	223	8	797ce39602f0f78081eb44a21da0d9443f7fd9cf
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYN3 EYA1 ITPR2 PKP2 SMPD3 PABIR2 DNAH1 HMCN1	5.18e-06	189	223	8	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 SLC26A4 TOX3 ADAMTS15 KIAA1217 TENM1 PLCXD3	5.38e-06	190	223	8	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 ADARB2 PTPRZ1 PKP2 CIT GRPR KMO N4BP2	5.81e-06	192	223	8	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	IQGAP2 MYO5A DOCK11 ITPR2 TBXAS1 OLFML2B APBA1 CD86	6.04e-06	193	223	8	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK2 MAP1B ATP8A2 ADGRB3 TENM2 NRXN3 SYNE1 SETBP1	6.76e-06	196	223	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IQGAP2 MYO5A DOCK11 TBXAS1 OLFML2B KCNAB2 KMO CD86	6.76e-06	196	223	8	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 EYA1 ADARB2 TENM2 PTPRZ1 PKP2 KIAA1217 SETBP1	7.01e-06	197	223	8	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 PKP2 MUC16 KIAA1217	7.28e-06	198	223	8	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MAP1B DOCK11 TENM2 AFF2 OLFML2B SUSD5 SPRY4 ATP1A4	7.83e-06	200	223	8	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRB3 EYA1 ADARB2 PTPRZ1 TOX3 PKP2 MUC16 KIAA1217	7.83e-06	200	223	8	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-SERPINF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQGAP2 DOCK11 ADARB2 PTPRZ1 PKP2 NOX4 KMO AUTS2	7.83e-06	200	223	8	c4e08cf539c12bb7c61be6d44b4f074bb460f526
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-SERPINF1-L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQGAP2 DOCK11 ADARB2 PTPRZ1 PKP2 NOX4 KMO AUTS2	7.83e-06	200	223	8	f922f9f223cbfed71b8e3115b16b51dc4d7b66b8
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1B DOCK11 TENM2 OLFML2B SYNE1 PHTF2 SUSD5 ATP1A4	7.83e-06	200	223	8	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQGAP2 DOCK11 ADARB2 PTPRZ1 PKP2 NOX4 KMO AUTS2	7.83e-06	200	223	8	913487e065dd580c9cbcbb3c3fc76a8d446f8856
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IQGAP2 SLC26A4 GATAD2B SUPT6H PKP2 OLFML2B ANKRD33B	8.27e-06	144	223	7	e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	PCSK2 MAP1B IQGAP2 ADGRB3 NRXN3 PTPRZ1 ANKRD33B	1.23e-05	153	223	7	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	MAP1B PKP2 SMPD3 MYRF MUC16 FAM153B ANKRD33B	1.39e-05	156	223	7	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	1.71e-05	161	223	7	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	2.00e-05	165	223	7	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SMPD3 MYRF MUC16 FAM153B EFNB3 CHST4 ANKRD33B	2.25e-05	168	223	7	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SMPD3 MYRF MUC16 FAM153B EFNB3 CHST4 ANKRD33B	2.25e-05	168	223	7	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	LA-16._Neuronal\|World / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	2.25e-05	168	223	7	2fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 FAM153B KIAA1217	2.25e-05	168	223	7	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	2.25e-05	168	223	7	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	2.33e-05	169	223	7	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 FAM153B KIAA1217	2.33e-05	169	223	7	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	Mild-Treg\|World / Disease group and Cell class	GCNT1 PHTF2 IKZF4 HMCN1 TNFRSF8 ATP1A4 FAM124B	2.42e-05	170	223	7	f3f177534badca34e1ae8671b7f583ee6688e14b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNAB2 NOX4 ACSF2 KMO SUGCT SLC17A1 TENM1	2.52e-05	171	223	7	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	2.71e-05	173	223	7	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	Tuft-tuft-4\|World / Class top	ITGA9 ITPR2 MDN1 SLC25A12 SPRY4 FAM124B EDRF1	2.81e-05	174	223	7	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	2.81e-05	174	223	7	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A ANKRD33B	2.92e-05	175	223	7	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCFD2 MAP1B SLC26A4 ZNF594 KCNF1 PTPRZ1 TPST1	2.92e-05	175	223	7	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK11 ADARB2 PTPRZ1 PKP2 AFF2 CIT GRPR	3.03e-05	176	223	7	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B IQGAP2 TENM2 FRMD1 RYR3 ATP10A PDE4DIP	3.14e-05	177	223	7	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TDRD9 ITGA9 TENM2 NYNRIN PIP5K1A CH25H HMCN1	3.14e-05	177	223	7	75cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 TP53INP1 TDRD9 MAP1B DOCK11 NRXN3 CIT	3.14e-05	177	223	7	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B IQGAP2 TENM2 FRMD1 RYR3 ATP10A PDE4DIP	3.25e-05	178	223	7	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	3.37e-05	179	223	7	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KDM3B EYA1 PTPRZ1 TOX3 CLUH CELSR3 NIN	3.49e-05	180	223	7	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EYA1 GCNT1 NRXN3 PTPRZ1 DDR1 SH2D3A CH25H	3.49e-05	180	223	7	255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	3.49e-05	180	223	7	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	PCSK2 IQGAP2 ADGRB3 NRXN3 PTPRZ1 KIAA1217 ANKRD33B	3.62e-05	181	223	7	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 ADARB2 PTPRZ1 PKP2 NOX4 KMO	3.62e-05	181	223	7	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	RV\|World / Chamber and Cluster_Paper	EYA1 ITGA9 CHN2 TENM2 PKP2 PLCXD3 MYOM2	3.62e-05	181	223	7	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 PTPRZ1 TOX3 KIAA1217 TENM1 PLCXD3	3.62e-05	181	223	7	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 ATP8A2 TENM2 FRMD1 RYR3 APBA1 ATP10A	3.62e-05	181	223	7	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B ZCCHC14 EVA1A TOX3 CIT PLEK2 SPRY4	3.62e-05	181	223	7	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 OLFML2B SYNE1 DEPDC1 CIT PLK4 NIN	3.62e-05	181	223	7	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 OLFML2B SYNE1 DEPDC1 CIT PLK4 NIN	3.62e-05	181	223	7	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 ATP8A2 TENM2 FRMD1 RYR3 APBA1 ATP10A	3.62e-05	181	223	7	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	3.75e-05	182	223	7	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNAB2 NOX4 ACSF2 KMO SUGCT SLC17A1 TENM1	3.88e-05	183	223	7	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	CDH26 EYA1 NRXN3 PTPRZ1 TOX3 MUC16 KIAA1217	3.88e-05	183	223	7	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 ATP10A PDE4DIP ANKRD33B	3.88e-05	183	223	7	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	Adult-Epithelial-basal_cell\|Adult / Lineage, Cell type, age group and donor	CDH26 EYA1 ITGA9 PTPRZ1 C2orf78 HMCN1 KIAA1217	3.88e-05	183	223	7	00a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 ATP10A PDE4DIP ANKRD33B	3.88e-05	183	223	7	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EYA1 ITGA9 NRXN3 EVA1A MYRF DDR1 SPRYD7	3.88e-05	183	223	7	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR3 DNAH10 DNAH1 HMCN1 TENM1 MYOM2 ATP1A4	4.02e-05	184	223	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 ADARB2 PTPRZ1 PKP2 GRPR KMO N4BP2	4.02e-05	184	223	7	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR3 DNAH10 DNAH1 HMCN1 TENM1 MYOM2 ATP1A4	4.02e-05	184	223	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR3 DNAH10 DNAH1 HMCN1 TENM1 MYOM2 ATP1A4	4.02e-05	184	223	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EYA1 ITGA9 NRXN3 EVA1A MYRF DDR1 SPRYD7	4.16e-05	185	223	7	3bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IQGAP2 MYO5A GCNT1 ITPR2 TBXAS1 APBA1 CD86	4.16e-05	185	223	7	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CHN2 TENM2 PKP2 FAM13C PDE4DIP PLCXD3 MYOM2	4.16e-05	185	223	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MAP1B ITGA9 NRXN3 OLFML2B IKZF4 HMCN1 RAI2	4.16e-05	185	223	7	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A ATP8A2 RYR3 MDN1 DNAH10 ACSF2 LRRC46	4.16e-05	185	223	7	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 SLC26A4 TOX3 ADAMTS15 KIAA1217 TENM1	4.16e-05	185	223	7	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IQGAP2 TENM2 FRMD1 RYR3 APBA1 ATP10A PDE4DIP	4.16e-05	185	223	7	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 TOX3 AFF2 NOX4 TENM1 PLCXD3	4.30e-05	186	223	7	948815663c212c4311329d503b5991cbbbff9808
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 SLC26A4 AFF2 KIAA1217 TENM1 PLCXD3	4.30e-05	186	223	7	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SCFD2 IQGAP2 ITPR2 EVA1A TOX3 RBMS1 SUGCT	4.45e-05	187	223	7	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B IQGAP2 TENM2 FRMD1 RYR3 ATP10A PDE4DIP	4.45e-05	187	223	7	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 ADARB2 PTPRZ1 PKP2 GRPR KMO N4BP2	4.61e-05	188	223	7	6ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 TOX3 AFF2 KIAA1217 TENM1 PLCXD3	4.61e-05	188	223	7	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 ADARB2 PTPRZ1 PKP2 GRPR KMO N4BP2	4.61e-05	188	223	7	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA9 ADARB2 TUB PTPRZ1 TOX3 KY SUSD5	4.61e-05	188	223	7	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA9 ADARB2 TUB PTPRZ1 TOX3 KY SUSD5	4.61e-05	188	223	7	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PCSK2 SLC26A4 RYR3 KCNF1 SUPT6H RC3H2 ANKRD33B	4.76e-05	189	223	7	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 TOX3 ADAMTS15 KIAA1217 TENM1 PLCXD3	4.76e-05	189	223	7	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 TOX3 AFF2 KIAA1217 TENM1 PLCXD3	4.92e-05	190	223	7	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 TOX3 AFF2 KIAA1217 TENM1 PLCXD3	4.92e-05	190	223	7	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 SLC26A4 PTPRZ1 TOX3 KIAA1217 TENM1 PLCXD3	4.92e-05	190	223	7	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 DOCK11 SLC26A4 TOX3 KIAA1217 TENM1 PLCXD3	4.92e-05	190	223	7	8c9c230a509afaeee50644153974a5642b01a2b8
Disease	Intellectual Disability	MAP1B ATP8A2 SDCCAG8 NAGLU KDM3B ZMYM2 NF1 ADSL ZBTB40 PUF60 SYNE1 POLR3B MTOR SETBP1	5.80e-06	447	215	14	C3714756
Disease	Malignant neoplasm of breast	CEP85L ITGA9 ZCCHC14 TMEM161A NOP9 NF1 TOX3 TBXAS1 SYNE1 PIGS SH2D3A MANEA SLC39A12 TCL1B MTOR N4BP2 SETBP1 TENM1 CPSF3 TP53BP1	1.26e-04	1074	215	20	C0006142
Disease	protein-tyrosine sulfotransferase 1 measurement	ADSL TPST1	3.14e-04	4	215	2	EFO_0801970
Disease	severe acute respiratory syndrome, COVID-19	ATP8A2 ADARB2 TENM2 TOX3 WRN KCNAB2 ACSF2 KIAA1217 PDE4DIP AUTS2 TUBD1	4.73e-04	447	215	11	EFO_0000694, MONDO_0100096
Disease	Tourette syndrome	TENM2 RBMS1 MUC16 POLR3B	4.85e-04	50	215	4	EFO_0004895
Disease	total blood protein measurement	IQGAP2 NYNRIN CH25H PHTF2 DNAH1 NFATC2IP SLC18A1 CD86 SUSD5 TUBD1 ANKRD33B	4.91e-04	449	215	11	EFO_0004536
Disease	alkaline phosphatase measurement	USP34 SLC26A4 NT5DC1 JAK1 NF1 ADSL ATRIP NYNRIN ZBTB40 MYRF CLUH COG4 ATF7 SLC17A1 STKLD1 CNOT1 TP53BP1 KLHL17	4.92e-04	1015	215	18	EFO_0004533
Disease	Profound Mental Retardation	NAGLU ZMYM2 NF1 ZBTB40 POLR3B SETBP1	5.61e-04	139	215	6	C0020796
Disease	Mental Retardation, Psychosocial	NAGLU ZMYM2 NF1 ZBTB40 POLR3B SETBP1	5.61e-04	139	215	6	C0025363
Disease	Mental deficiency	NAGLU ZMYM2 NF1 ZBTB40 POLR3B SETBP1	5.61e-04	139	215	6	C0917816
Disease	crescentic glomerulonephritis (implicated_via_orthology)	MMP12 MTOR	7.78e-04	6	215	2	DOID:13139 (implicated_via_orthology)
Disease	eye disease (implicated_via_orthology)	EYA1 MYRF	7.78e-04	6	215	2	DOID:5614 (implicated_via_orthology)
Disease	unipolar depression, schizophrenia	VPS45 ZCCHC14 BAG5	7.79e-04	25	215	3	EFO_0003761, MONDO_0005090
Disease	Senior-Loken syndrome (is_implicated_in)	SDCCAG8 NPHP1	1.08e-03	7	215	2	DOID:0050576 (is_implicated_in)
Disease	platelet reactivity measurement, thrombus formation measurement	N4BP2 SETBP1	1.08e-03	7	215	2	EFO_0004985, EFO_0007615
Disease	Renal dysplasia and retinal aplasia	SDCCAG8 NPHP1	1.08e-03	7	215	2	cv:C0403553
Disease	cerebral infarction (is_implicated_in)	ITGA9 MYRF TBXAS1	1.21e-03	29	215	3	DOID:3526 (is_implicated_in)
Disease	lung carcinoma, family history of lung cancer	PCSK2 ADARB2 TUB	1.21e-03	29	215	3	EFO_0001071, EFO_0006953
Disease	Epileptic encephalopathy	RYR3 ADSL MTOR	1.34e-03	30	215	3	C0543888
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	BCL3 TASOR MYRF PCSK9 DNAH10 USP24 SLC18A1 TP53BP1	1.39e-03	291	215	8	EFO_0008317, EFO_0020946
Disease	seasonal gut microbiome measurement	PCSK2 DCDC1 ZMYM2 ADARB2 TTLL2	1.40e-03	112	215	5	EFO_0007753
Disease	hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement	MYRF PCSK9	1.44e-03	8	215	2	EFO_0800583
Disease	triacylglycerol 58:6 measurement	TENM2 TOX3	1.44e-03	8	215	2	EFO_0010440
Disease	fear of minor pain measurement	NAGLU TENM1 FAM124B	1.48e-03	31	215	3	EFO_0008340
Disease	QRS duration	USP34 CEP85L MYRF DDR1 OLFML2B HMCN1 SETBP1 MYOM2	1.62e-03	298	215	8	EFO_0005055
Disease	response to aromatase inhibitor	MUC16 TCL1B CNOT1	1.62e-03	32	215	3	GO_0061477
Disease	intelligence, self reported educational attainment	SDCCAG8 BAG5 APBA1 IKZF4 CELSR3	1.70e-03	117	215	5	EFO_0004337, EFO_0004784
Disease	mortality	ITGA9 NRXN3 NYNRIN DEPDC1 AUTS2 NIN	1.74e-03	173	215	6	EFO_0004352
Disease	nephronophthisis (implicated_via_orthology)	SDCCAG8 NPHP1	1.84e-03	9	215	2	DOID:12712 (implicated_via_orthology)
Disease	underweight body mass index status	ADGRB3 NRXN3	1.84e-03	9	215	2	EFO_0005936
Disease	Testicular Germ Cell Tumor	TIPIN RFWD3 SUGCT SPRY4	2.01e-03	73	215	4	EFO_1000566
Disease	response to hydrochlorothiazide, diastolic blood pressure change measurement	PKD1L1 PLCXD3	2.29e-03	10	215	2	EFO_0005202, EFO_0006945
Disease	JT interval	CEP85L PKP2 TASOR CLUH OLFML2B MYOM2 CNOT1	2.37e-03	248	215	7	EFO_0007885
Disease	language impairment	NOP9 SUGCT	2.78e-03	11	215	2	EFO_0005425
Disease	N-acetylphenylalanine measurement	C2orf78 SLC17A1	2.78e-03	11	215	2	EFO_0800019
Disease	serum gamma-glutamyl transferase measurement	TP53INP1 IQGAP2 DOCK11 NAGLU ITGA9 TENM2 NF1 EVA1A HACE1 HSD17B13 DYRK1A CIT ZZZ3 STKLD1 TP53BP1	3.02e-03	914	215	15	EFO_0004532
Disease	energy intake	TENM2 PHTF2 ANKRD33B DNPEP NIN	3.06e-03	134	215	5	EFO_0003939
Disease	Epilepsy, Cryptogenic	KCNAB2 DYRK1A WDR45 AUTS2	3.08e-03	82	215	4	C0086237
Disease	Awakening Epilepsy	KCNAB2 DYRK1A WDR45 AUTS2	3.08e-03	82	215	4	C0751111
Disease	Aura	KCNAB2 DYRK1A WDR45 AUTS2	3.08e-03	82	215	4	C0236018
Disease	alcohol use disorder (implicated_via_orthology)	PCSK2 KDM3B RYR3 BRD7 AUTS2 ATP1A4	3.16e-03	195	215	6	DOID:1574 (implicated_via_orthology)
Disease	sexual dimorphism measurement	KMT2B SYN3 BCL3 EYA1 SPATA31C1 NT5DC1 NRXN3 NF1 NYNRIN TASOR MYRF DNAH10 PARP10 NFATC2IP SLC17A1 SLC18A1 TP53BP1	3.19e-03	1106	215	17	EFO_0021796
Disease	Renal dysplasia and retinal aplasia (disorder)	SDCCAG8 NPHP1	3.32e-03	12	215	2	C0403553
Disease	high grade glioma (is_marker_for)	DDR1 MTOR BRD7	3.55e-03	42	215	3	DOID:3070 (is_marker_for)
Disease	Bardet-Biedl Syndrome	SDCCAG8 NPHP1	3.91e-03	13	215	2	C0752166
Disease	diastolic blood pressure, systolic blood pressure	SCFD2 DCDC1 MAP1B SDCCAG8 ADAMTS15 SMG9 FAM13C SLC39A12 SUGCT N4BP2 SETBP1 CPSF3	3.92e-03	670	215	12	EFO_0006335, EFO_0006336
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	BCL3 MYRF PCSK9 DNAH10 DNAH1 SLC18A1 TP53BP1	4.27e-03	276	215	7	EFO_0004612, EFO_0020943
Disease	total lipids in small LDL	BCL3 NYNRIN PCSK9	4.89e-03	47	215	3	EFO_0022168
Disease	obesity (implicated_via_orthology)	RSC1A1 TUB ITPR2 STIM1 HSDL1 DNAH10	5.07e-03	215	215	6	DOID:9970 (implicated_via_orthology)
Disease	response to paliperidone, schizophrenia symptom severity measurement	IQGAP2 VPS45 TENM2 KIF2B USP24 HMCN1	5.18e-03	216	215	6	EFO_0007925, EFO_0007927
Disease	amyotrophic lateral sclerosis, age at onset	NRXN3 SLC18A1	5.21e-03	15	215	2	EFO_0004847, MONDO_0004976
Disease	Situs ambiguus	BCL9L PKD1L1	5.21e-03	15	215	2	C0266642
Disease	glycerate measurement	RYR3 HMCN1	5.21e-03	15	215	2	EFO_0021029
Disease	Colonic Neoplasms	ATP7A MMP12 NOX4 MTOR TP53BP1	5.22e-03	152	215	5	C0009375
Disease	autism spectrum disorder (implicated_via_orthology)	SYN3 NRXN3 PKP2 SHANK1 DYRK1A	5.22e-03	152	215	5	DOID:0060041 (implicated_via_orthology)
Disease	acute myeloid leukemia (is_marker_for)	NF1 CD86 BRD7	5.49e-03	49	215	3	DOID:9119 (is_marker_for)
Disease	Colorectal Carcinoma	PCSK2 MAP1B ADARB2 NF1 ADAMTS15 SHANK1 SYNE1 WRN ZZZ3 SETBP1 TENM1 EDRF1	5.64e-03	702	215	12	C0009402
Disease	cholesteryl esters to total lipids in IDL percentage	BCL3 PCSK9 TP53BP1	5.81e-03	50	215	3	EFO_0022247
Disease	QRS amplitude, QRS complex	CAND2 CEP85L OLFML2B	5.81e-03	50	215	3	EFO_0005054, EFO_0007742
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	BCL3 MYRF PCSK9 USP24 SLC18A1 TP53BP1	5.91e-03	222	215	6	EFO_0008317, EFO_0020943
Disease	syndromic intellectual disability (implicated_via_orthology)	DYRK1A AUTS2	5.93e-03	16	215	2	DOID:0050888 (implicated_via_orthology)
Disease	amygdala volume change measurement	PKD1L1 SPATA31C1	5.93e-03	16	215	2	EFO_0021490
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	BCL3 NT5DC1 NYNRIN PCSK9	6.02e-03	99	215	4	EFO_0004611, EFO_0007878
Disease	QT interval	CEP85L EYA1 ITPR2 PKP2 TASOR MYRF CLUH OLFML2B KCNAB2 CNOT1	6.06e-03	534	215	10	EFO_0004682
Disease	alpha fetoprotein measurement	USP34 DYRK1A ATP1A4 TP53BP1	6.23e-03	100	215	4	EFO_0010583
Disease	Malignant tumor of colon	ATP7A MMP12 NOX4 MTOR TP53BP1	6.30e-03	159	215	5	C0007102
Disease	creatinine measurement	CAND2 DCDC1 USP11 SDCCAG8 EYA1 ADARB2 TUB ADSL PIP5K1A ATF7 PHTF2 RFWD3 ZZZ3 CELSR3 SETBP1	6.52e-03	995	215	15	EFO_0004518
Disease	calcium measurement	SCFD2 ZMYM2 EYA1 NT5DC1 STIM1 FAM120C NYNRIN PIP5K1A PHTF2 CD86 ATP1A4	6.64e-03	628	215	11	EFO_0004838
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	BCL3 NT5DC1 NYNRIN PCSK9	6.68e-03	102	215	4	EFO_0004329, EFO_0004611
Disease	response to phenylephrine	IQGAP2 ATP10A	6.69e-03	17	215	2	EFO_0010152
Disease	Moyamoya Disease	ATP7A NF1	6.69e-03	17	215	2	C0026654

Protein segments in the cluster

Peptide	Gene	Start	Entry
MPSETHAMLATLARV	SUGCT	1	Q9HAC7
GTTLMRAMLDAHPDI	TPST1	81	O60507
GSAPMQLHLRATIRM	APOM	76	O95445
MDMGNQHPSISRLQE	BAG5	1	Q9UL15
KPRSSLGMHMLESVQ	C2orf78	621	A6NCI8
DRTMIGEPMNFVHLT	CDC42SE1	26	Q9NRR8
HIMSEPEEITTMSGQ	CPSF3	366	Q9UKF6
DLGSPQLAMHSIREM	DNPEP	441	Q9ULA0
GMLDMLRGDSSHVVS	BLOC1S4	101	Q9NUP1
GHSRTLQEMEMSLPE	BRD7	471	Q9NPI1
MMGDHTIKSQRPRSV	ADGRB3	256	O60242
SKMNIGMETLPHERL	ADGRB3	1326	O60242
MIMSGFSRLLNHAVP	ALKBH1	276	Q13686
ESKMVTLHRMGPNLQ	COG4	71	Q9H9E3
MGPLTQHSSMTNLVR	AFF2	1281	P51816
HRTSMVRQAALPIME	GJA10	476	Q969M2
PMLLHVAAQIASGMR	DDR1	741	Q08345
MPHSIMRVDIAGRDV	ACTR1B	176	P42025
MVFTQAPAEIMGHLR	AQP10	1	Q96PS8
ESVGRIMPHTEARIM	ACSF2	431	Q96CM8
RTELSMPIQSHVIMT	ATF7	461	P17544
HLTMRQGADREESPM	DYRK1A	736	Q13627
KPTGMIRIHQMNSEL	CD86	116	P42081
ITKALLPSMMERNHG	HSD17B13	151	Q7Z5P4
LPSMMERNHGHIVTV	HSD17B13	156	Q7Z5P4
MSAIVRSPEHQPSAM	CIT	1316	O14578
PDMRGQATMVLSSAH	ATP8A2	1056	Q9NTI2
STVDMSMPVREHTLL	ATP10A	1371	O60312
ANHMMSPTLIQIDRA	ADAMTS15	386	Q8TE58
DGGVLDHMVRMTTSL	ANKRD33B	301	A6NCL7
QHRVLDQMRSFGMTP	NAGLU	226	P54802
HSMVDESLITGEAMP	ATP7A	866	Q04656
IIRSNSLPPMDVMHS	RC3H2	711	Q9HBD1
GHTVMEKLPSGMEIS	RAI2	371	Q9Y5P3
EHTMSLQPASMISPL	RBMS1	326	P29558
PDKNHTTIRSVLMEM	RFWD3	656	Q6PCD5
ARVMSHRMEGVGQLP	ADARB2	596	Q9NS39
DPITRDHMGSVMAQV	EDC4	1351	Q6P2E9
MRLPLSHSPEHVEMA	EVA1A	1	Q9H8M9
NVVMRHDIPDLGTMS	IMP4	166	Q96G21
MIGPTHGQMTVTRLV	JAK1	1091	P23458
TGQLDTSTLEMMHAP	MMP12	76	P39900
PGLLEAETMRHIFMN	ITPR2	1266	Q14571
TPRTMHTSVMALDRL	KBTBD3	391	Q8NAB2
EMMDLQHGSLFLRTP	LDHA	61	P00338
SLIITGGSIHPMEME	DPH5	251	Q9H2P9
TLTQRFPHSEMTTLM	MUC16	7061	Q8WXI7
FSHSQMSTLMRRGPE	MUC16	7941	Q8WXI7
HSQMTALMSRTPGDV	MUC16	9116	Q8WXI7
MTEIMSSNRIHIPDS	MUC16	9911	Q8WXI7
GSDSPIQTDHMMERL	DCDC1	516	M0R2J8
ISEILNSHGNIMPMD	NSUN3	276	Q9H649
PETGEERDLMVHNIM	NOP9	76	Q86U38
SMDPVHGDISRAMRN	MDN1	2291	Q9NU22
RASHGTKMMTPEVLA	NT5DC1	86	Q5TFE4
MQVTLIPTHDSEVMR	MAP1B	2416	P46821
TFEDIHMLVGSNMPI	EDRF1	311	Q3B7T1
MLSAHPETSMIRTVN	KY	351	Q8NBH2
HDPDLVEINRSMMSP	LRRC53	641	A6NM62
GMSHSALVPMLKEQR	LNX2	661	Q8N448
HVAGIAAMMLSAEPE	PCSK9	391	Q8NBP7
MEMQDLTSPHSRLSG	EYA1	1	Q99502
PMVMADQHRSVSELL	HACE1	36	Q8IYU2
EDVSQDPGLSHLMMS	NRXN3	236	Q9Y4C0
DPGLSHLMMSEQARE	NRXN3	241	Q9Y4C0
IHPMNSISSLDRTRM	AUTS2	1031	Q8WXX7
VDMPKLHDAMGTRSL	DEPDC1	631	Q5TB30
MSGSTPFQMRLVHLD	HEXD	1	Q8WVB3
SVDPRLIHVMLMDNS	KDM3B	241	Q7LBC6
HPEVQVLLLTMMSTA	GGA2	511	Q9UJY4
MVGILMRHSEEGETP	KMT2B	1471	Q9UMN6
TEHLLRMEMQPTLTD	LRRC46	221	Q96FV0
CLLSMPTRNHMDITT	FAM120A	531	Q9NZB2
ATNTTLPHMLMSQRV	GATAD2B	251	Q8WXI9
VMPLGARTASHMTKD	NDUFB8	21	O95169
SQVEPPSSDAMMHAR	PTPRZ1	906	P23471
LTDHLPVAMRLMVSS	SMPD3	636	Q9NY59
TMETDDHMGGIPARN	PIP5K1A	376	Q99755
DPNTPMEETVRAMTH	KCNAB2	161	Q13303
PSVIETHMRQMRSAS	MANEA	166	Q5SRI9
IISVMSHPSDVMEIR	NOX4	311	Q9NPH5
GVMHPRTTFLMVDEE	HMCN1	5561	Q96RW7
TTIMSRHSLEEGLDM	PABIR2	51	Q7Z309
RRMELSMGPIQANHT	GBA	86	P04062
PSQSEVMGEPHLMVE	POMP	121	Q9Y244
EIHRDSTLDPSLMEM	ALPG	296	P10696
LMVPLMHEVDTSITG	ITGA9	761	Q13797
MRPPEDSTLTTLHDM	CHN2	436	P52757
EPTLGMDAMASEHRD	FRMD1	41	Q8N878
VRSNIHMVLCMSPIG	DNAH1	2706	Q9P2D7
LVMAAPLSMEHGTVT	CDC45	491	O75419
DTTMENIMLRVHPDG	GABRR3	156	A8MPY1
MDETQGPLAMTVHLL	FAM124B	1	Q9H5Z6
SIRMPSHNTVELMVV	IGSF1	401	Q8N6C5
APMNIRRSTHDLVAM	KLHL17	561	Q6TDP4
VSQGIPMRARMIHSL	KMO	76	O15229
FQTVVMLEMTPELGH	HLA-DOB	181	P13765
ENIMASLERSMHPEL	DOCK11	301	Q5JSL3
HPRTGTMMLKSSEVL	DNAH17	1431	Q9UFH2
AIVRPMDIQASHALM	GRPR	141	P30550
IPSLLSMSTRNHMDI	FAM120C	581	Q9NX05
SMSTRNHMDITIPPL	FAM120C	586	Q9NX05
EQIGLHGSRPLQDMM	BCL9L	536	Q86UU0
ADTQETMMDHPLRTI	APBA1	531	Q02410
LRTIGPSCLHDSMEM	CEP85L	196	Q5SZL2
GIMHLTINDMPTLTD	FBXL13	351	Q8NEE6
IAHGTPVMRLSMPTQ	ELF2	501	Q15723
PGMQVEVLADSLHMR	IL10RB	116	Q08334
DFGSMVIHLMLPETR	MALSU1	171	Q96EH3
TMHRQLLAPVEGRMA	CDH26	746	Q8IXH8
SGMTVLQRLMISDSH	GP5	71	P40197
ASLMVHVVLPGMVER	HSDL1	181	Q3SXM5
HQFDQVMPGVSMLIR	ATRIP	746	Q8WXE1
TPNIMLSIDRMEHPS	CELSR3	2321	Q9NYQ7
LMGENNLETERMPSH	GCNT1	236	Q02742
PMEHPLSADIAMATR	BCL3	116	P20749
AMEEPTQTGSNLHML	CAND2	416	O75155
ETMLTRHTTMVVGPT	DNAH10	2101	Q8IVF4
VSEMPMERDRGAAHS	EFNB3	181	Q15768
SLPMTHRMQLSETNR	PSG11	186	Q9UQ72
ASLSVTSTRMHEPQM	RSC1A1	131	Q92681
TSTRMHEPQMFLGEK	RSC1A1	136	Q92681
LVEMLPEMTHVQTQR	SLC39A12	646	Q504Y0
LMHFPSNLVTEMLRV	SLC38A10	261	Q9HBR0
SMMRHSLPSIFVAGL	PKD1L1	2641	Q8TDX9
DMMNVTLLGCHPLTT	CH25H	186	O95992
EIRDLEMVPDSMLHS	IKZF4	291	Q9H2S9
EMVPDSMLHSSSERP	IKZF4	296	Q9H2S9
ATGVHMMQVDPATLA	FAM153B	306	P0C7A2
APRMLKSHIGNSEMS	KIF2B	561	Q8N4N8
RMSLQSTDLISHPML	NPHP1	596	O15259
PTSRMMLAVHTEPAA	NYNRIN	571	Q9P2P1
AEQVSSMPMGSLEHE	PARP10	346	Q53GL7
ILMVRSLVVSPHEDM	MTOR	1636	P42345
VISEHSSLLPQDMMS	PIGS	146	Q96S52
RSPLTLALRVGDHMM	MIDN	136	Q504T8
VMDSSMPLIGEHVEE	SYN3	366	O14994
EISGMIMNRVNSHIP	PHTF2	481	Q8N3S3
VMVQPLLDSRMSHSR	SPRY4	16	Q9C004
MTHSSVLPSQMLDVE	SUSD5	431	O60279
PEMLSEQEHMSISGS	PUF60	431	Q9UHX1
VMMTAGRCHTLLSPV	SYNE1	5846	Q8NF91
QMDKLPSRHAISEVM	SYNE1	6906	Q8NF91
QTHRDALTMSEDRPM	TMEM161A	251	Q9NX61
TGSTMLLRETSLMPH	TDRD9	1206	Q8NDG6
QLMEMQHLRSTATPS	NIN	1956	Q8N4C6
HRITPDMSLQNMKGT	RGPD2	1401	P0DJD1
SMPTGNMRASQELHD	SPATA31A6	1056	Q5VVP1
PLRSLEHEETNMPTM	SDCCAG8	101	Q86SQ7
SRAMIDSRTPEEMKH	IQGAP2	1341	Q13576
MTEFHLQSQMPSIRL	OR5AU1	1	Q8NGC0
EGIMQIPRNSHRTTM	OVCH1	991	Q7RTY7
NLTMVVMVNSTDPHG	SLC17A1	41	Q14916
SLARHLMTLVMDPLQ	ADSL	306	P30566
MPTGNMRASQELHDL	SPATA31A7	1061	Q8IWB4
QVMSMARPQLSHTIL	SMG9	476	Q9H0W8
PVGTSAIHMSLLEMR	KIAA1217	636	Q5T5P2
VVPLSGMMVRHAQSS	KIAA1217	876	Q5T5P2
TLMSTEEGRPHFELM	SETD7	171	Q8WTS6
MQVLHPAARMLVELS	CCT4	81	P50991
LLSVTMPSMVRHSLQ	TENM1	1911	Q9UKZ4
LLAVTMPSVARHSMS	TENM2	1961	Q9NT68
VSQHLIRPLMGMSLA	NHEJ1	131	Q9H9Q4
EQVGSMGLVEMLHRS	WDR45	46	Q9Y484
IAESRILPLMTIGMH	WRN	1276	Q14191
GMPDLAHVMRILSAE	PPM1B	331	O75688
PGHTNDVMVNMIALT	SCFD2	301	Q8WU76
LSMSNLHEATMPVLL	FAM13C	501	Q8NE31
DLMSARRSNMGHKEP	SPATA31C1	926	P0DKV0
RMSEPLQSVVDHMAT	NFATC2IP	281	Q8NCF5
AVSPREALMEAMHTV	OLFML2B	436	Q68BL8
RMVMHSAASPTQAPI	PLK4	836	O00444
GHAMPRLAVTNTTMT	STIM1	161	Q13586
IPLGRDMHSLVMRND	SPRYD7	91	Q5W111
QMMSPLQIERSLSVH	STYX	181	Q8WUJ0
SMMVFRIGIPDLHQT	SHANK1	71	Q9Y566
MVTSDHIVPGDMARE	TASOR	1171	Q9UK61
SSQTHVLMMKGAPER	ATP1A4	506	Q13733
MVTIRSHMLTPFVEE	SLC25A12	186	O75746
ISSLSMKAQPERMHV	CHST4	31	Q8NCG5
AVLMSERVMGTEHPN	CLUH	1046	O75153
HPTMSVDEVLEMLQR	CNOT1	861	A5YKK6
LESRTQLVTMCHMGP	SUPT6H	1011	Q7KZ85
MPTGNMRASQELHDL	SPATA31A3	1061	Q5VYP0
MATLPESMHSIPLTN	PLCXD3	16	Q63HM9
MLSVRNIPHMSENSL	TUBD1	271	Q9UJT1
MVLDARHSASPMGVQ	TBXAS1	281	P24557
VVGHTMERSPMHVRN	ZNF440	561	Q8IYI8
MHDSNTGIRSSPNME	PLEK2	136	Q9NYT0
RHLANMMGEDPETFT	MRPS9	86	P82933
LMVGSVVLSMAPDEH	SLC26A4	146	O43511
MPTGNMRASQELHDL	SPATA31A5	1061	Q5VU36
QQPSRSHLMRSGSVM	TRAPPC14	521	Q8WVR3
VHMAAAGIPSMSTRD	SAGE1	136	Q9NXZ1
ADMPAMSTRDQHATI	SAGE1	376	Q9NXZ1
HRQMVPASITDMLLE	STKLD1	311	Q8NE28
HPHIEVMRIDGTMDS	RYR3	1251	Q15413
VMGALLMPQVSRLEH	SH2D3A	416	Q9BRG2
HPQLSAMIRGQDAEM	TSPYL1	286	Q9H0U9
TSPMENLLIEHPSMS	TP53INP1	116	Q96A56
RGLMSQPLMETCHSV	TNFRSF8	461	P28908
SQMSMDHEELLRTPG	NF1	641	P21359
ERHSSNSLPGLMMDL	VPS45	396	Q9NRW7
LALMTHITTDMEDGP	POLR3B	496	Q9NW08
EMSGQDFHLSTREMP	TTLL2	491	Q9BWV7
SIVHMTDAARSGVMP	TOX3	156	O15405
MSESMVETHDPILGS	TP53BP1	956	Q12888
MAVHTRELLSSGQMP	TCL1B	66	O95988
QPGRALVMTRMDSIS	ZC3H12B	691	Q5HYM0
MMQGEAHPSASLIDR	TMEM209	1	Q96SK2
DGRDMNLMITHVTSL	ZMYM2	206	Q9UBW7
QMLSAASHITPIRML	ZCCHC14	496	Q8WYQ9
TGVTQTPRHLVMGMT	TRBV4-3	21	A0A589
LRLDTHPAMVTVLEM	TRAP1	601	Q12931
RHLQQGSESPMMIGE	USP24	2596	Q9UPU5
MRHLPSQESGIREMH	ZNF594	56	Q96JF6
NMMVLVSRAVEHPSV	STARD7	241	Q9NQZ5
MQLTDMEHVSLPGTR	PIEZO1	706	Q92508
MGPVRMISSGHELTT	USP34	1276	Q70CQ2
GMDPITRQVGQHIEM	UBR2	516	Q8IWV8
MATIEAVIHMAREAP	SETBP1	1506	Q9Y6X0
TGVTQTPRHLVMGMT	TRBV4-2	21	A0A539
FSMTERLPPIQSMVH	WDR87	61	Q6ZQQ6
VSAQMMSLSEPQEHR	ZZZ3	361	Q8IYH5
AVSMLEADHMLPSRI	PKP2	356	Q99959
SVIVPGMNMVHERVS	TUB	386	P50607
KHTGISPERMMVADV	USP11	531	P51784
GNDMLMNTPRAHTVE	TIPIN	226	Q9BVW5
MISHMTSLAPGEREV	ZBTB40	486	Q9NUA8
MPIMGHLVDLRHTSV	SLC18A1	411	P54219
TLTHLGARMMELTNV	KCNF1	271	Q9H3M0
LQPMIVSGMLEHETI	MYO5A	1621	Q9Y4I1
MRAVTPENHESMTSI	N4BP2	1206	Q86UW6
ISSSEHMRIGGSEEM	MYOM2	1271	P54296
HLLEEPTSMEVQPMT	PDE4DIP	201	Q5VU43
NVKVMGSLMHPSDLR	MYRF	576	Q9Y2G1
MTDIIEASSISHMPQ	PCSK2	246	P16519