Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.50e-0827912113GO:0005096
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 RELN TNC CRELD2 TINAGL1 FBN1 FBN2 PXDN LTBP4

2.19e-061881219GO:0005201
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

IPO5 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.44e-0650712114GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

IPO5 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.44e-0650712114GO:0030695
GeneOntologyMolecularFunctionmolecular function activator activity

VEGFC TBC1D3E RELN TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B CRHR2 TG LEFTY1 FBN1 FBN2 EPHA2 MAP3K9 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

4.40e-06123312122GO:0140677
GeneOntologyMolecularFunctioncalcium ion binding

TPO HSPG2 FSTL4 CRELD2 USP6 FAT2 SULF2 FBN1 FBN2 SUSD1 ANKEF1 LTBP3 MMP13 LTBP4 CRB2

4.78e-0574912115GO:0005509
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.75e-0465612113GO:0008047
GeneOntologyMolecularFunctionpeptidase activity

TPP2 RELN PSEN2 ADAM12 TINAGL1 USP6 PRSS50 OTUD4 TPSG1 MMP13 KLK13 ZRANB1

6.23e-0465412112GO:0008233
GeneOntologyMolecularFunctioncytokine receptor binding

VEGFC SMURF1 GRIN2B TFF2 TYK2 LEFTY1 PXDN IL1RAP

8.11e-043241218GO:0005126
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR TBC1D3C TBC1D3B NEDD9 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

3.35e-1510912314GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR TBC1D3C TBC1D3B NEDD9 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.23e-1024412314GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D BCR ALS2CL TBC1D3C TBC1D3B NEDD9 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.52e-0933512315GO:0043087
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D GRIN2B BCR TBC1D3C TBC1D3B NEDD9 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.95e-0749912315GO:0051345
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

VEGFC TBC1D3E RELN TBC1D3 TBC1D3H TBC1D3L PSEN2 TBC1D3D GRIN2B BCR TBC1D3C TBC1D3B NEDD9 FBN1 EPHA2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.07e-05102812319GO:0043085
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D GRIN2B BCR ALS2CL TBC1D3C TBC1D3B NEDD9 EPHA2 TBC1D3I TBC1D3G CRB2 TBC1D3K TBC1D3F

1.82e-0587812317GO:0051336
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

VEGFC HJV ELAPOR2 NPR1 PSEN2 MYO1C FSTL4 SMURF1 BCR TYK2 NEDD9 LEFTY1 SULF2 FBN1 FBN2 EPHA2 LTBP3 LTBP4 CRB2

7.58e-05118612319GO:0007167
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

HJV ELAPOR2 FSTL4 SMURF1 FBN1 CRB2

1.35e-041311236GO:0030510
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

VEGFC HJV ELAPOR2 FSTL4 SMURF1 SULF2 FBN1 FBN2 LTBP4 CRB2

1.83e-0441212310GO:0090287
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

2.10e-0441232GO:0035583
GeneOntologyBiologicalProcessnotochord formation

EPHA2 CRB2

2.10e-0441232GO:0014028
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

HJV ELAPOR2 FSTL4 SMURF1 LEFTY1 FBN1 FBN2 LTBP4 CRB2

2.38e-043471239GO:0090092
GeneOntologyBiologicalProcessresponse to growth factor

VEGFC HJV ELAPOR2 MYO1C TNC FSTL4 SMURF1 LEFTY1 SULF2 FBN1 FBN2 EPHA2 LTBP3 LTBP4 CRB2

2.48e-0488312315GO:0070848
GeneOntologyBiologicalProcesspositive regulation of molecular function

VEGFC TBC1D3E RELN TBC1D3 TBC1D3H TBC1D3L PSEN2 TBC1D3D GRIN2B BCR TBC1D3C TBC1D3B NEDD9 FBN1 EPHA2 TBC1D3I IL1RAP TBC1D3G TBC1D3K TBC1D3F

3.00e-04143012320GO:0044093
GeneOntologyCellularComponentexternal encapsulating structure

HSPG2 RELN ADAMTSL1 TNC LAMC3 PKHD1L1 TINAGL1 FREM2 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4

3.05e-0565812214GO:0030312
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2 LTBP4

5.31e-05131223GO:0001527
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 RELN ADAMTSL1 TNC LAMC3 TINAGL1 FREM2 FBN1 FBN2 PXDN LTBP3 LTBP4

6.45e-0553012212GO:0062023
GeneOntologyCellularComponentbasement membrane

HSPG2 TNC LAMC3 FREM2 FBN1 PXDN

8.13e-051221226GO:0005604
GeneOntologyCellularComponentextracellular matrix

HSPG2 RELN ADAMTSL1 TNC LAMC3 TINAGL1 FREM2 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4

1.21e-0465612213GO:0031012
MousePhenoincreased trabecular bone mass

SMURF1 SIGLEC15 LTBP3 MMP13

1.91e-0525914MP:0010872
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.26e-144912111SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

3.22e-145312111PF00566
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.00e-145512111IPR000195
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.00e-145512111PS50086
DomainEGF-like_CS

TPO HSPG2 RELN TNC CRELD2 LAMC3 ADAM12 FAT2 FBN1 FBN2 SUSD1 EPHA2 LTBP3 LTBP4 MEGF10 CRB2

1.29e-1126112116IPR013032
DomainEGF_2

TPO HSPG2 RELN TNC CRELD2 LAMC3 ADAM12 FAT2 FBN1 FBN2 SUSD1 EPHA2 LTBP3 LTBP4 MEGF10 CRB2

1.62e-1126512116PS01186
DomainEGF-like_dom

TPO HSPG2 RELN TNC CRELD2 LAMC3 ADAM12 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 MEGF10 CRB2

7.53e-1124912115IPR000742
DomainEGF_1

TPO HSPG2 RELN TNC CRELD2 LAMC3 ADAM12 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 MEGF10 CRB2

1.05e-1025512115PS00022
DomainEGF

TPO HSPG2 RELN TNC CRELD2 LAMC3 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 MEGF10 CRB2

3.89e-1023512114SM00181
DomainEGF_3

TPO HSPG2 RELN TNC CRELD2 ADAM12 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 MEGF10 CRB2

3.89e-1023512114PS50026
DomainGrowth_fac_rcpt_

HSPG2 ELAPOR2 TNC CRELD2 LAMC3 FBN1 FBN2 SUSD1 EPHA2 LTBP3 LTBP4

5.62e-0915612111IPR009030
DomainEGF_CA

TPO HSPG2 CRELD2 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

6.69e-0912212110SM00179
DomainEGF-like_Ca-bd_dom

TPO HSPG2 CRELD2 FAT2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

7.84e-0912412110IPR001881
DomainTB

FBN1 FBN2 LTBP3 LTBP4

5.78e-0871214PF00683
Domain-

FBN1 FBN2 LTBP3 LTBP4

1.15e-07812143.90.290.10
DomainTB_dom

FBN1 FBN2 LTBP3 LTBP4

2.06e-0791214IPR017878
DomainTB

FBN1 FBN2 LTBP3 LTBP4

2.06e-0791214PS51364
DomainEGF_Ca-bd_CS

TPO CRELD2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

2.20e-07971218IPR018097
DomainEGF_CA

TPO CRELD2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

2.57e-07991218PS01187
DomainASX_HYDROXYL

TPO CRELD2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

2.78e-071001218PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

TPO CRELD2 FBN1 FBN2 SUSD1 LTBP3 LTBP4 CRB2

4.36e-071061218IPR000152
DomainEGF_CA

TPO CRELD2 FBN1 FBN2 SUSD1 LTBP3 LTBP4

1.42e-06861217PF07645
Domain-

HSPG2 ADAMTSL1 TNC FSTL4 MCAM OBSL1 KIRREL2 PKHD1L1 SIGLEC15 PXDN NFATC2 EPHA2 IL1RAP SDK1 EBF4

2.53e-05663121152.60.40.10
DomainhEGF

FBN2 LTBP3 MEGF10 CRB2

3.04e-05281214PF12661
DomainIg-like_fold

HSPG2 ADAMTSL1 TNC FSTL4 MCAM OBSL1 KIRREL2 PKHD1L1 SIGLEC15 PXDN NFATC2 EPHA2 IL1RAP SDK1 EBF4

5.20e-0570612115IPR013783
DomainLaminin_EGF

HSPG2 CRELD2 LAMC3 MEGF10

1.04e-04381214IPR002049
DomainFBN

FBN1 FBN2

1.24e-0431212IPR011398
DomainIGc2

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 PXDN SDK1

1.48e-042351218SM00408
DomainIg_sub2

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 PXDN SDK1

1.48e-042351218IPR003598
DomainIg_I-set

HSPG2 ADAMTSL1 FSTL4 OBSL1 KIRREL2 PXDN SDK1

2.40e-041901217IPR013098
DomainI-set

HSPG2 ADAMTSL1 FSTL4 OBSL1 KIRREL2 PXDN SDK1

2.40e-041901217PF07679
DomainIG

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 SIGLEC15 PXDN IL1RAP SDK1

4.16e-0442112110SM00409
DomainIg_sub

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 SIGLEC15 PXDN IL1RAP SDK1

4.16e-0442112110IPR003599
DomainEphrin_rec_like

ELAPOR2 TG EPHA2

5.50e-04251213SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

ELAPOR2 TG EPHA2

5.50e-04251213IPR011641
DomainPEROXIDASE_1

TPO PXDN

6.14e-0461212PS00435
DomainEGF_extracell

RELN TNC ADAM12 MEGF10

6.18e-04601214IPR013111
DomainEGF_2

RELN TNC ADAM12 MEGF10

6.18e-04601214PF07974
DomaincEGF

FBN1 FBN2 LTBP3

6.18e-04261213PF12662
DomaincEGF

FBN1 FBN2 LTBP3

6.18e-04261213IPR026823
DomainIPT

PKHD1L1 NFATC2 EBF4

6.93e-04271213SM00429
DomainDM_2

DMRTB1 DMRTA2

8.56e-0471212PS50809
DomainDM

DMRTB1 DMRTA2

8.56e-0471212SM00301
Domain-

DMRTB1 DMRTA2

8.56e-04712124.10.1040.10
DomainDM_DNA-bd

DMRTB1 DMRTA2

8.56e-0471212IPR001275
DomainDM

DMRTB1 DMRTA2

8.56e-0471212PF00751
DomainDM_1

DMRTB1 DMRTA2

8.56e-0471212PS40000
DomainTIG

PKHD1L1 NFATC2 EBF4

1.04e-03311213PF01833
DomainDMRT/dsx/mab-3

DMRTB1 DMRTA2

1.14e-0381212IPR026607
DomainLAMININ_IVA

HSPG2 LAMC3

1.14e-0381212PS51115
DomainLaminin_B

HSPG2 LAMC3

1.14e-0381212PF00052
DomainLamB

HSPG2 LAMC3

1.14e-0381212SM00281
DomainLaminin_IV

HSPG2 LAMC3

1.14e-0381212IPR000034
DomainIPT

PKHD1L1 NFATC2 EBF4

1.15e-03321213IPR002909
DomainIG_LIKE

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 SIGLEC15 PXDN IL1RAP SDK1

1.35e-0349112110PS50835
DomainEGF_Lam

HSPG2 LAMC3 MEGF10

1.49e-03351213SM00180
DomainLaminin_EGF

HSPG2 LAMC3 MEGF10

1.49e-03351213PF00053
DomainIg-like_dom

HSPG2 ADAMTSL1 FSTL4 MCAM OBSL1 KIRREL2 SIGLEC15 PXDN IL1RAP SDK1

1.61e-0350312110IPR007110
DomainAn_peroxidase

TPO PXDN

1.81e-03101212PF03098
DomainHaem_peroxidase_animal

TPO PXDN

1.81e-03101212IPR019791
DomainHaem_peroxidase

TPO PXDN

1.81e-03101212IPR010255
DomainPEROXIDASE_3

TPO PXDN

1.81e-03101212PS50292
Domain-

TPO PXDN

1.81e-031012121.10.640.10
DomainLAM_G_DOMAIN

HSPG2 FAT2 CRB2

1.90e-03381213PS50025
DomainLaminin_G_2

HSPG2 FAT2 CRB2

2.20e-03401213PF02210
DomainLamG

HSPG2 FAT2 CRB2

2.89e-03441213SM00282
DomainOTU

OTUD4 ZRANB1

3.10e-03131212PF02338
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L MRPL45 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K

7.37e-10999110M46448
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP3 LTBP4

1.42e-058913M47850
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

HSPG2 TNC LAMC3 ADAM12 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4

2.30e-053009110M610
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP3 LTBP4

5.09e-0532914MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP3 LTBP4

9.12e-0537914M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP3 LTBP4

1.12e-0439914MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP3 LTBP4

1.81e-0444914M26969
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

SMURF1 FBN1 LTBP3 LTBP4

2.34e-0447914M646
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

TNC ADAM12 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4

2.59e-04258918MM14572
PathwayPID_INTEGRIN_A9B1_PATHWAY

VEGFC TNC ADAM12

5.40e-0425913M118
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

6.84e-28111231116863688
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D USP6 TBC1D3F

1.49e-10412348406013
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E FOXK2 TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F

2.41e-1074123816625196
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 RELN ADAMTSL1 TNC CRELD2 TINAGL1 FBN1 FBN2 PXDN LTBP4

7.38e-101751231028071719
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C USP6

7.43e-105123412604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D USP6 TBC1D3F

7.43e-10512348471161
Pubmed

FOXD1 is required for 3D patterning of the kidney interstitial matrix.

HSPG2 TNC FREM2 FBN2

1.04e-0713123436335435
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HSPG2 ADAMTSL1 TNC TINAGL1 FREM2 FBN1 PXDN LTBP4

1.54e-07167123822159717
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2 LTBP4

1.72e-074123312429738
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

1.72e-074123312359748
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

VEGFC HSPG2 TNC ADAM12 TINAGL1 FBN1 PXDN IL1RAP LTBP4

2.68e-07248123924006456
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

HSPG2 FBN1 FBN2

4.29e-075123323493297
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

HSPG2 TNC MCAM TINAGL1 FBN1 LTBP3 LTBP4

9.40e-07146123727068509
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

TNC FBN1 FBN2

2.39e-068123323055981
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

HSPG2 TNC FBN2

6.98e-0611123338303699
Pubmed

Functional proteomics mapping of a human signaling pathway.

HSPG2 NPR1 SMURF1 MCAM TINAGL1 NEDD9 FBN2 SUSD1 LTBP3 IL1RAP SDK1

8.61e-065911231115231748
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

HSPG2 TNC TINAGL1 FBN1 FBN2 LTBP4

8.96e-06135123628675934
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

IPO5 HSPG2 NAGA ACTL6A LRPPRC FBN2 PXDN SUSD1 LTBP3 LTBP4 FBXO34

1.21e-056131231122268729
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

1.24e-052123212399449
Pubmed

The role of molecular diagnostics in aneurysmal and simple bone cysts - a prospective analysis of 19 lesions.

USP6 NFATC2

1.24e-052123234089379
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

1.24e-052123221851253
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

1.24e-052123230044367
Pubmed

Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.

FBN1 LTBP3

1.24e-052123226494287
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

1.24e-052123221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

1.24e-052123215131124
Pubmed

Control of lung development by latent TGF-β binding proteins.

LTBP3 LTBP4

1.24e-052123220945348
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

1.24e-052123220404337
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

1.24e-05212328791520
Pubmed

Elevated Thyroid Autoantibodies Aggravate Stroke Severity in Euthyroidism with Acute Ischemic Stroke.

TPO TG

1.24e-052123235256895
Pubmed

MMP13 Regulates Aggressiveness of Pediatric Multiple Myeloma Through VEGF-C.

VEGFC MMP13

1.24e-052123225966777
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

1.24e-05212328307578
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

1.24e-05212327744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

1.24e-052123226408953
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

1.24e-052123218006876
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

1.24e-052123224833718
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

1.24e-052123224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

1.24e-052123220529844
Pubmed

Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability.

TPO TG

1.24e-052123227305979
Pubmed

Expression of the Na+/I- symporter gene in human thyroid tumors: a comparison study with other thyroid-specific genes.

TPO TG

1.24e-052123210487692
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

1.24e-052123223133647
Pubmed

Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.

FBN1 LTBP3

1.24e-052123230306291
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

1.24e-05212321852206
Pubmed

Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.

HSPG2 FBN1

1.24e-052123215657057
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

1.24e-052123212429739
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

1.24e-052123212524050
Pubmed

LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.

FBN1 LTBP3

1.24e-052123229625025
Pubmed

Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.

HSPG2 FBN1

1.24e-052123223104139
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

1.24e-05212328120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

1.24e-052123235419902
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

1.24e-052123210504303
Pubmed

The prevalence of iodine deficiency, serum thyroglobulin, anti-thyroglobulin and thyroid peroxidase antibody levels in the urban areas of Kayseri, Central Anatolia.

TPO TG

1.24e-052123219194833
Pubmed

Lack of a role for cross-reacting anti-thyroid antibodies in chronic idiopathic urticaria.

TPO TG

1.24e-052123220182447
Pubmed

Anti-Helicobacter Pylori, anti-thyroid peroxidase, anti-thyroglobulin and anti-gastric parietal cells antibodies in Czech population.

TPO TG

1.24e-052123218271683
Pubmed

The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency.

HSPG2 FBN1

1.24e-052123238545339
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

1.24e-052123225524144
Pubmed

Fibrillin-2 and Tenascin-C bridge the age gap in lung epithelial regeneration.

TNC FBN2

1.24e-052123228662401
Pubmed

Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism.

TPO TG

1.24e-052123231867598
Pubmed

Antibodies to thyroid peroxidase arise spontaneously with age in NOD.H-2h4 mice and appear after thyroglobulin antibodies.

TPO TG

1.24e-052123220573721
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

1.24e-052123216407178
Pubmed

Is HSPG2 a modifier gene for Marfan syndrome?

HSPG2 FBN1

1.24e-052123232514132
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

1.24e-052123210359653
Pubmed

Evidence of a combined cytotoxic thyroglobulin and thyroperoxidase epitope-specific cellular immunity in Hashimoto's thyroiditis.

TPO TG

1.24e-052123222259066
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

HSPG2 ACTL6A TINAGL1 FREM2 LRPPRC FBN1 FBN2

1.36e-05219123731353912
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

HSPG2 TNC FBN1 FBN2 PXDN

1.41e-0586123528327460
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HSPG2 NPR1 NAGA FSTL4 MCAM CRELD2 LAMC3 ADAM12 SULF2 FBN1 FBN2 PXDN EPHA2 LTBP3 IL1RAP

2.33e-0512011231535696571
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

HSPG2 TNC FREM2

2.34e-0516123315878328
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

FSTL4 MCAM OBSL1 KIRREL2 PXDN IL1RAP

2.52e-05162123625826454
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

HSPG2 TNC TINAGL1 FBN1 LTBP4

2.53e-0597123527559042
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

HSPG2 TNC FBN1 FBN2

3.02e-0550123423658023
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

HSPG2 TNC TINAGL1 FBN1 LTBP4

3.08e-05101123520551380
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

TNC LRSAM1 CRELD2 ADAM12 HOXA1 DLGAP3 FBN1 LTBP3 LTBP4 MEGF10

3.19e-055601231021653829
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

FBN1 FBN2

3.71e-053123210825173
Pubmed

Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures.

TPO TG

3.71e-053123215562032
Pubmed

TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.

TPO TG

3.71e-053123234896620
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

FBN1 FBN2

3.71e-053123230201140
Pubmed

Diversity of human copy number variation and multicopy genes.

TBC1D3E TBC1D3G

3.71e-053123221030649
Pubmed

Genotypes and phenotypes of congenital goitre and hypothyroidism caused by mutations in dual oxidase 2 genes.

TPO TG

3.71e-053123224735383
Pubmed

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation.

VEGFC TPO

3.71e-053123215452344
Pubmed

Geleophysic Dysplasia

FBN1 LTBP3

3.71e-053123220301776
Pubmed

Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.

TPO TG

3.71e-053123231585887
Pubmed

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

FBN1 FBN2

3.71e-053123220855508
Pubmed

Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse.

RELN TNC

3.71e-05312327506500
Pubmed

The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest.

ADGRB1 BCR

3.71e-053123231461398
Pubmed

Lack of association between MMP13 (rs3819089), ADAM12 (rs3740199-rs1871054) and ADAMTS14 (rs4747096) genotypes and advanced-stage knee osteoarthritis.

ADAM12 MMP13

3.71e-053123234145804
Pubmed

Relationship of clinical features and laboratory parameters to thyroid echogenicity measured by standardized grey scale ultrasonography in patients with Hashimoto's thyroiditis.

TPO TG

3.71e-053123212709678
Pubmed

Identification of putative genetic variants in major depressive disorder patients in Pakistan.

RELN BCR

3.71e-053123235040003
Pubmed

Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.

TPO TG

3.71e-053123224057177
Pubmed

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.

TPO TG

3.71e-053123227525530
Pubmed

Biological variation of thyroid autoantibodies and thyroglobulin.

TPO TG

3.71e-053123217902201
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

C1QTNF8 ATP13A4 ADAMTSL1 LRSAM1 CRELD2 KIRREL2 ADAM12 TINAGL1 LEFTY1 SULF2 SUSD1 TSPAN13 HSD17B14

4.85e-059851231312975309
Pubmed

Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.

VEGFC TPO TG

5.48e-0521123323707896
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

HSPG2 LRSAM1 FBN1 LTBP3 LTBP4

6.48e-05118123521078624
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

FBN1 FBN2

7.41e-054123225406291
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP3 LTBP4

7.41e-054123215611103
Pubmed

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

FBN1 FBN2

7.41e-054123220729550
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2

7.41e-054123225034023
Pubmed

ADAM12-cleaved ephrin-A1 contributes to lung metastasis.

ADAM12 EPHA2

7.41e-054123223686306
Pubmed

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.

ADGRB1 GRIN2B

7.41e-054123210748157
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP3 LTBP4

7.41e-054123211104663
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2

7.41e-054123216835936
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MRPL45 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

9.19e-1514912312chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

7.44e-0699123517q12
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 ADAMTSL1 FSTL4 OBSL1 KIRREL2 PXDN SDK1

5.09e-06161767593
GeneFamilyImmunoglobulin like domain containing

HSPG2 FSTL4 MCAM OBSL1 KIRREL2 IL1RAP SDK1

1.66e-05193767594
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP3 LTBP4

1.04e-044762628
GeneFamilyOTU domain containing

OTUD4 ZRANB1

2.28e-0317762669
CoexpressionNABA_MATRISOME

VEGFC TPO HSPG2 C1QTNF8 RELN ADAMTSL1 TNC CRELD2 LAMC3 ADAM12 TINAGL1 LEFTY1 FREM2 SULF2 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4 MEGF10

9.40e-09102612121M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN TNC CRELD2 LAMC3 TINAGL1 FBN1 FBN2 PXDN LTBP3 LTBP4

2.09e-0819112110MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN TNC CRELD2 LAMC3 TINAGL1 FBN1 FBN2 PXDN LTBP3 LTBP4

2.68e-0819612110M3008
CoexpressionNABA_MATRISOME

VEGFC TPO HSPG2 RELN ADAMTSL1 TNC CRELD2 LAMC3 ADAM12 TINAGL1 LEFTY1 FREM2 SULF2 FBN1 FBN2 PXDN LTBP3 MMP13 LTBP4 MEGF10

3.70e-08100812120MM17056
CoexpressionNABA_CORE_MATRISOME

HSPG2 RELN TNC CRELD2 LAMC3 TINAGL1 FBN1 FBN2 PXDN LTBP3 LTBP4

5.31e-0827012111MM17057
CoexpressionNABA_CORE_MATRISOME

HSPG2 RELN TNC CRELD2 LAMC3 TINAGL1 FBN1 FBN2 PXDN LTBP3 LTBP4

6.40e-0827512111M5884
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

IPO5 TBC1D3 TBC1D3H TM7SF3 ETFDH CRELD2 PELI2 TBC1D3C OTUD4 TBC1D3F

8.18e-0636712110M41159
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

RELN PSEN2 PELI2 BCR PKHD1L1 SULF2 FBN1 NFATC2 KBTBD11 LTBP4

1.80e-0540212110M45754
CoexpressionHEBERT_MATRISOME_TNBC_BONE_BRAIN_LIVER_LUNG_METASTASTASES

HSPG2 ADAMTSL1 TINAGL1

2.65e-05131213M48004
CoexpressionMARTENS_TRETINOIN_RESPONSE_UP

C1QTNF8 PAXX LAMC3 KIRREL2 SIGLEC15 ZNF835 TFF2 TG PXDN EPHA2 PRSS50 DMRTB1 DMRTA2 TPSG1

4.15e-0585512114M2098
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B FREM2 TBC1D3G TBC1D3K TBC1D3F

9.65e-119012110PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

LRRC75B TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B LEFTY1 HSD17B14 TBC1D3G TBC1D3K TBC1D3F

2.73e-1021312113PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

LRRC75B TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B LEFTY1 HSD17B14 TBC1D3G TBC1D3K TBC1D3F

2.73e-1021312113PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

HSPG2 RELN LRRC75B TBC1D3 TBC1D3H TBC1D3L TBC1D3D SLC5A9 TBC1D3C TBC1D3B TSPAN13 HSD17B14 TBC1D3G TBC1D3K TBC1D3F

4.34e-1032012115PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TYK2 FBN2 MZF1 TBC1D3G MEGF10 TBC1D3K TBC1D3F

7.81e-1028112114PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B TYK2 FBN2 MZF1 TBC1D3G MEGF10 TBC1D3K TBC1D3F

7.81e-1028112114PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

LRRC75B TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC TBC1D3C TBC1D3B LEFTY1 TBC1D3G TBC1D3K TBC1D3F

1.43e-0824212112PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

HSPG2 ELAPOR2 RELN LRRC75B TBC1D3 TBC1D3H TBC1D3L TBC1D3D TNC MCAM SLC5A9 TBC1D3C TBC1D3B LEFTY1 SULF2 FBN2 PXDN EPHA2 TSPAN13 HSD17B14 TBC1D3G FBXO34 TBC1D3K TBC1D3F

2.92e-08115312124PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

STK36 ELAPOR2 TBC1D3 TBC1D3H TBC1D3L MYO1C TBC1D3D TNC MCAM TBC1D3C TBC1D3B ZNF71 NEDD9 SULF2 FBN1 FBN2 PXDN MZF1 EPHA2 HSD17B14 TBC1D3G LTBP4 CRB2 TBC1D3K TBC1D3F

6.45e-07146612125PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 LAMC3 LCT PKHD1L1 CAMKV ATP6V0A4 LTBP4 CRB2

4.44e-081831238ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 ATP13A4 RELN GRIN2B PKHD1L1 FREM2 FBN2 SDK1

4.63e-0818412382cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 ATP13A4 RELN GRIN2B PKHD1L1 FREM2 FBN2 SDK1

4.63e-081841238ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 ATP13A4 RELN GRIN2B PKHD1L1 FREM2 FBN2 SDK1

4.63e-0818412382b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ADAMTSL1 CLIP2 BCR ADAM12 PKHD1L1 EPHA2 KBTBD11

4.83e-081851238bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 MEX3D BCR HOXA1 HOXB8 FBN1 EPHA2 LTBP4

5.04e-081861238c116cc9f41971622264434ebe29d18e719b0ae19
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ADAMTSL1 KIF26A ADGRB1 MCAM LAMC3 CRHR2 EPHX3

5.25e-081871238ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNC PELI2 LAMC3 ADAM12 FBN1 PXDN NFATC2 LTBP4

7.85e-08197123885a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNC PELI2 LAMC3 ADAM12 FBN1 PXDN NFATC2 LTBP4

7.85e-081971238e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 RELN TNC NEDD9 FBN2 IL1RAP CRB2

7.28e-0718112375f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 RELN TNC NEDD9 FBN2 IL1RAP CRB2

7.28e-071811237c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

TPO HSPG2 ADAMTSL1 BCR PKHD1L1 NEDD9 SULF2

9.06e-0718712377876dcb4800c2e54874df3d933efb79307a64a97
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A ALS2CL TINAGL1 EPHA2 SLC28A2 TSPAN13

9.39e-071881237ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A ALS2CL TINAGL1 EPHA2 SLC28A2 TSPAN13

9.39e-071881237e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A ALS2CL TINAGL1 EPHA2 SLC28A2 TSPAN13

9.39e-0718812370fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PELI2 BCR PKHD1L1 NEDD9 SULF2

9.72e-07189123775c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PELI2 BCR PKHD1L1 NEDD9 SULF2

9.72e-071891237c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 RELN ADAMTSL1 TNC PKHD1L1 MZF1 LTBP4

1.01e-061901237f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11 LTBP4

1.01e-061901237a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 RELN ADAMTSL1 TNC PKHD1L1 MZF1 LTBP4

1.01e-061901237a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

BCR TINAGL1 FBN1 NFATC2 SLC28A2 TSPAN13 LTBP4

1.01e-061901237ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11 LTBP4

1.01e-0619012370bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 RELN ADAMTSL1 TNC PKHD1L1 MZF1 LTBP4

1.01e-06190123757c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11 LTBP4

1.01e-06190123726e2237f65cb43723c5da853831b40df2982d6e4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.04e-061911237a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.08e-0619212379093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

HSPG2 NPR1 ADAMTSL1 PELI2 BCR PKHD1L1 SULF2

1.08e-061921237c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.08e-0619212379ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PELI2 BCR PKHD1L1 NEDD9 SULF2

1.12e-06193123701c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PELI2 BCR PKHD1L1 NEDD9 SULF2

1.12e-0619312372531266bc57339d4e2b22a88817008e32b8c1598
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PELI2 BCR PKHD1L1 NEDD9 SULF2

1.16e-061941237b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.24e-061961237a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 ATP13A4 MYO1C SLC5A9 ALS2CL NEDD9 TSPAN13

1.24e-061961237eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.24e-0619612373e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TNC LAMC3 ADAM12 FBN1 PXDN LTBP4

1.28e-0619712376d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 ATP13A4 MYO1C ALS2CL NEDD9 PXDN TSPAN13

1.33e-061981237a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

VEGFC ADAMTSL1 TNC LAMC3 FBN1 LTBP4 SDK1

1.33e-061981237bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

VEGFC TPO HSPG2 MCAM TINAGL1 NEDD9 SULF2

1.37e-061991237d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VEGFC HSPG2 MCAM BCR TINAGL1 SULF2 LTBP4

1.37e-0619912376a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNC ADAM12 FBN1 LTBP3 MMP13 KLK13 MEGF10

1.42e-062001237ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCelldistal-Endothelial-Vein|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VEGFC HSPG2 NPR1 MCAM PKHD1L1 TINAGL1 SULF2

1.42e-0620012376acf7afe122f81a95c4c66f4d0878d997b57127a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TBC1D3L TNC LAMC3 ZNF835 HOXA1

3.02e-061441236cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 TBC1D3L TNC LAMC3 ZNF835 HOXA1

3.02e-06144123641eaeca54b3c39de417597267cbdb1f195dd885a
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

RELN KIF26A GRIN2B PKHD1L1 FBN1 KBTBD11

6.62e-061651236b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN GRIN2B PKHD1L1 SULF2 FBN1 LTBP4

7.85e-0617012366035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC MCAM BCR TINAGL1 PRSS50 LTBP4

7.85e-0617012368e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN GRIN2B PKHD1L1 SULF2 FBN1 LTBP4

7.85e-061701236c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN GRIN2B PKHD1L1 SULF2 FBN1 LTBP4

7.85e-061701236dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC MCAM BCR TINAGL1 PRSS50 LTBP4

7.85e-06170123667d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC ADAMTSL1 TNC LAMC3 FBN1 NFATC2

9.27e-061751236910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ATP13A4 MYO1C KIRREL2 ALS2CL LEFTY1 PXDN

9.27e-061751236bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC ADAMTSL1 TNC LAMC3 FBN1 NFATC2

9.27e-061751236f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ADAMTSL1 BCR DNAJB3 KBTBD11 LTBP4

9.57e-061761236057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ADAMTSL1 BCR DNAJB3 KBTBD11 LTBP4

9.57e-061761236b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC HSPG2 PKHD1L1 ANKEF1 KLK13 LTBP4

9.89e-061771236d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADAMTSL1 KIF26A TNC ADAM12 MMP13 SDK1

1.02e-0517812368f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 TM7SF3 GRIN2B LEFTY1 SULF2 EPHX3

1.05e-0517912367aa4137f672dadb3be92009cde6e0ea60a15372d
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11

1.12e-051811236b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A MEX3D GRIN2B HOXA1 DMRTA2 SDK1

1.12e-0518112367af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11

1.12e-051811236cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR ADAM12 PKHD1L1 KBTBD11

1.12e-051811236ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR DNAJB3 KBTBD11 LTBP4

1.16e-0518212362cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TNC TM7SF3 LAMC3 LEFTY1 FBN2 MEGF10

1.16e-051821236812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR DNAJB3 KBTBD11 LTBP4

1.16e-0518212360cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 PSEN2 MCAM TINAGL1 FBN1 LTBP4

1.16e-051821236c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 PSEN2 MCAM TINAGL1 FBN1 LTBP4

1.16e-051821236d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 BCR DNAJB3 KBTBD11 LTBP4

1.16e-0518212363e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSEN2 TM7SF3 MCAM PKHD1L1 TINAGL1 LTBP4

1.19e-05183123612e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MCAM TINAGL1 HOXB8 SLC28A2 LTBP4

1.19e-051831236c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 ADGRB1 MCAM LAMC3 CRHR2 EPHX3

1.19e-0518312368de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MCAM TINAGL1 HOXB8 SLC28A2 LTBP4

1.19e-051831236c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MCAM TINAGL1 HOXB8 SLC28A2 LTBP4

1.19e-05183123692eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

BCR SULF2 NFATC2 TSPAN13 SDK1 EBF4

1.23e-051841236c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TNC PELI2 ADAM12 TBC1D3C NFATC2 SDK1

1.23e-051841236d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STK36 MCAM TINAGL1 PXDN LTBP4

1.27e-051851236742350093d90f96735dc73e3360cdd749bae63fd
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ADAMTSL1 KIF26A MCAM LAMC3 FBN1

1.27e-051851236f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PELI2 SULF2 FBN1 CAMKV LTBP4 SDK1

1.27e-051851236d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VEGFC HSPG2 NPR1 GRIN2B SULF2 TSPAN13

1.31e-05186123692092f11ecce22c14f244e42c499af0822977e6f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 ATP13A4 ADAMTSL1 ALS2CL FBN2 TSPAN13

1.35e-0518712364ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 CLIP2 LAMC3 ADAM12 TINAGL1 SDK1

1.35e-05187123676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A TINAGL1 HOXB8 SLC28A2 LTBP4

1.35e-051871236a178b1fed80a0bf83aedb6262493ee17374734b5
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A TINAGL1 HOXB8 SLC28A2 LTBP4

1.35e-051871236e60cbccf5842f25123fd34b9475759b7424b32e9
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KIF26A TINAGL1 HOXB8 SLC28A2 LTBP4

1.35e-0518712362b8eda2812be0be68a6f01aa4038925d3d5b1e65
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 ATP13A4 ADAMTSL1 ALS2CL NEDD9 TSPAN13

1.39e-051881236eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

VEGFC HSPG2 ADAMTSL1 MCAM PKHD1L1 SULF2

1.39e-051881236d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC75B TNC NEDD9 SULF2 LTBP3 LTBP4

1.43e-051891236d00410010283dc6191ce9857d6c7952678fed588
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC ADAMTSL1 TNC LAMC3 FBN1 NFATC2

1.48e-0519012361121eb607a984c59fbffe7220837fc178745aa55
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 KIF26A ADAM12 TINAGL1 LTBP4

1.48e-051901236a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC ADAMTSL1 TNC LAMC3 FBN1 NFATC2

1.48e-051901236048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

HSPG2 NPR1 RELN TINAGL1 PXDN HSD17B14

1.48e-051901236bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC NPR1 KIF26A MCAM TINAGL1 LTBP4

1.48e-051901236cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 KIF26A ADAM12 TINAGL1 LTBP4

1.48e-05190123625525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC NPR1 KIF26A MCAM TINAGL1 LTBP4

1.48e-0519012365bf3d0beee69879c95265d07fba023626a7cc808
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

HSPG2 NPR1 RELN TINAGL1 PXDN HSD17B14

1.48e-05190123608437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

VEGFC HSPG2 MCAM TINAGL1 FBN1 PXDN

1.52e-051911236f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ADAMTSL1 BCR PKHD1L1 KBTBD11 LTBP4

1.52e-05191123648823a97c38263f2c6e58348214f5b62773a6368
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 TNC BCR ADAM12 LTBP4

1.52e-05191123651cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

TNC PELI2 LAMC3 ADAM12 FBN1 LTBP4

1.52e-05191123678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

BCR SULF2 NFATC2 TSPAN13 SDK1 EBF4

1.52e-0519112363480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADAMTSL1 TNC BCR ADAM12 LTBP4

1.52e-051911236a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ComputationalAdhesion molecules.

RELN TNC MCAM ADAM12 NEDD9 FBN1 FBN2

2.60e-05141677MODULE_122
Diseasevision disorder

TPO PXDN SDK1

2.72e-05161103MONDO_0021084
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

4.12e-0531102DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

8.22e-0541102DOID:0060249 (is_implicated_in)
DiseaseGeleophysic dysplasia

FBN1 LTBP3

1.37e-0451102C3489726
DiseaseAcromicric Dysplasia

FBN1 LTBP3

1.37e-0451102C0265287
Diseaseresponse to placebo

TPO PXDN

1.37e-0451102EFO_0008344
DiseaseDisproportionate short stature

HSPG2 OBSL1 FBN1 MMP13

2.01e-04771104C0878659
DiseaseThyroid Dyshormonogenesis 1

TPO TG

2.05e-0461102C1848805
Diseaseprimary dental caries

FSTL4 GRIN2B SUSD1

2.77e-04341103EFO_0600095
DiseaseGoiter

TPO TG

2.86e-0471102C0018021
Diseaseinvasive ductal carcinoma (is_marker_for)

VEGFC ADGRB1 MMP13

4.50e-04401103DOID:3008 (is_marker_for)
Diseasenicotine use

ACTR3B DMRTB1

4.87e-0491102EFO_0005430
Diseasepancreatic adenocarcinoma (is_marker_for)

VEGFC ADGRB1

6.08e-04101102DOID:4074 (is_marker_for)
DiseaseCongenital Hypothyroidism

TPO TG

1.05e-03131102C0010308
Diseasecongenital hypothyroidism (implicated_via_orthology)

TPO TG

1.22e-03141102DOID:0050328 (implicated_via_orthology)
Diseasemacrophage inflammatory protein 1b measurement

TBC1D3 MRPL45 TBC1D3B TBC1D3F

1.71e-031361104EFO_0008219
DiseaseFEV/FEC ratio

VEGFC HSPG2 ADAM12 TG FREM2 FBN1 CLCN4 OTUD4 ASPSCR1 LTBP3 LTBP4 CRB2

2.11e-03122811012EFO_0004713
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

2.50e-03201102EFO_0004751
Diseasetemporal lobe epilepsy (is_marker_for)

RELN GRIN2B

2.50e-03201102DOID:3328 (is_marker_for)
DiseaseOsteoarthritis of hip

TNC LTBP3

2.50e-03201102C0029410
Diseasecoronary atherosclerosis measurement, traffic air pollution measurement

SAMSN1 MEGF10

2.76e-03211102EFO_0007908, EFO_0007938
DiseaseCraniofacial Abnormalities

HSPG2 HOXA1 LTBP3 MMP13

2.81e-031561104C0376634
Diseasenicotine dependence

ADAMTSL1 DLGAP3 LTBP4

3.13e-03781103EFO_0003768
Diseaseretinal vasculature measurement

IPO5 TPO HSPG2 CRHR2 PXDN LTBP3 CRB2

3.29e-035171107EFO_0010554
DiseaseOvarian Serous Adenocarcinoma

STK36 CAMKV

3.31e-03231102C1335177
Diseasesmall cell lung carcinoma

ADAMTSL1 FSTL4 NEDD9

3.36e-03801103EFO_0000702
Diseaselow density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram

RELN SULF2

3.60e-03241102EFO_0004611, EFO_0006329, EFO_0007871
Diseasetemperament and character inventory

TG FBN2

3.60e-03241102EFO_0004825

Protein segments in the cluster

PeptideGeneStartEntry
GVYSPFRDFVCAGCP

ALS2CL

601

Q60I27
QGRGTYDFRPFPACS

ADAT3

236

Q96EY9
PGGATPVCVYTRDEV

ASPSCR1

131

Q9BZE9
GVYAIPPSACRDEAG

NEDD9

221

Q14511
VPCSGPGRVRTYQFD

ADGRB1

91

O14514
GTPPGYGCAADRAEE

BCR

431

P11274
PECGRGVSYSNPVFE

ATP13A4

1176

Q4VNC1
EEYGPSICRHNPVFG

ACTR3B

401

Q9P1U1
SYSAPGACEEPTERG

FBXO34

251

Q9NWN3
GYAGEDCPKVDFPTA

ACTL6A

26

O96019
GICFERVNSAGDPYG

ADAM12

546

O43184
CVIPEYAFPRRQDGG

ANKEF1

436

Q9NU02
DGAVGGVRYFECPAL

CLIP2

121

Q9UDT6
DGAVAGTRYFQCPPK

CLIP2

261

Q9UDT6
VRVFAPYACGSGIPE

CLCN4

171

P51793
AVFLGPGCVYAAAPV

NPR1

111

P16066
PGCVYAAAPVGRFTA

NPR1

116

P16066
RPAYEVFGSVCAADG

DMRTA2

151

Q96SC8
FCTGEFRKDGVPIGY

PPIH

46

O43447
YPGFPCNEKGDRAIV

OTUD4

666

Q01804
SGEYVCRAASGPGPE

HSPG2

2986

P98160
GLPAPDPCDYEGRFS

HJV

141

Q6ZVN8
GRPGACYVDIPADFV

HACL1

161

Q9UJ83
EPPRFVCYCEGEESG

PAXX

16

Q9BUH6
DFPCGQPDRPGVYTR

KLK13

236

Q9UKR3
VTGECRCPPGYTGAF

MEGF10

206

Q96KG7
EVPGDCVPSEGDYRF

OBSL1

576

O75147
YAKGRAPCAGPSREE

MMTAG2

51

Q9BU76
YPAVEFLGPCEQGER

NFATC2

346

Q13469
PRSSEAGAGAPAVFY

OR10S1

276

Q8NGN2
PGFLAYECVGTCRQP

LEFTY1

286

O75610
VYPPREVCGAGTAAI

LRSAM1

186

Q6UWE0
FVCVAEATFREGPPA

CRB2

866

Q5IJ48
AQPRPDAGGDFYLRC

FOXK2

101

Q01167
VPAPRYTVELACGFG

IL1RAP

351

Q9NPH3
RFPCDFGPGEVRYSH

FREM2

126

Q5SZK8
RACYAGPCSGEIPEF

ADAMTSL1

576

Q8N6G6
GPSYAVCEVEGAPLA

FAT2

4306

Q9NYQ8
CGVPDVGEYNVFPRT

MMP13

96

P45452
EEARPAAGTACLPFY

TPO

276

P07202
AGALVERPCPEYFNG

CRHR2

56

Q13324
APVGTAAPDDCDFGF

MEX3D

441

Q86XN8
EAGAAAGCGPAPYER

LRRC75B

16

Q2VPJ9
YASVVRCNGFPDPAT

LCT

1831

P09848
CQEPRGPTEAVGYFL

LRPPRC

571

P42704
QSPGVYLREDPVCGA

KIF26A

546

Q9ULI4
EADVSGGYPQCAPAV

HOXA1

116

P49639
GGDNYRPFCTEALPL

IPO5

936

O00410
RPCPAGTEPALGFEY

ELAPOR2

426

A8MWY0
HGNAVTFCEPYGPRE

RELN

236

P78509
CGFAQDLGGRPTVVY

HOXB8

26

P17481
PAFGCRPEYDNGLEE

OTOP1

561

Q7RTM1
SIYDGPEQRFCPAGV

ETFDH

551

Q16134
CGTPEYLAPEVVGRQ

CAMKV

181

Q8NCB2
DADPGPEGRAAACFF

DMRTB1

106

Q96MA1
GCTGGRPFEDPFEYV

DNAJB3

76

Q8WWF6
GCPGRFVYTALNEPT

EBF4

331

Q9BQW3
GFTGPQCERDYRTGP

FBN1

171

P35555
PESGECGPCEASVRY

EPHA2

371

P29317
EACRPSYVPVCGSDG

FSTL4

91

Q6MZW2
PFCLEGPDGSYRDLS

DLGAP3

286

O95886
TSLCPGCGEPVYFAE

CRIP3

121

Q6Q6R5
GPPGAACRRAYAAFS

C1QTNF8

106

P60827
AQGYAPAPDGRSCLD

LTBP3

771

Q9NS15
LRGYGPSDAPRDVDC

EPHX3

131

Q9H6B9
SPGSYRCVRDCDPGY

LTBP4

981

Q8N2S1
DESPYGVRVNCISPG

HSD17B14

171

Q9BPX1
RLPSVGPEDAGDYVC

KIRREL2

361

Q6UWL6
CDPVFDFGTGPRNAA

EIF2A

306

Q9BY44
GFTGPQCERDYRTGP

FBN2

201

P35556
EGSFRCICPPGYEVK

FBN2

2036

P35556
TPGSYVCVCPDGFEE

CRELD2

311

Q6UXH1
DTGPYVCEAALPGSA

SDK1

356

Q7Z5N4
QSYLCIPFPRGEDGD

MAP3K9

696

P80192
EEVATCVGRNGYPIP

MCAM

156

P43121
VVDTETCRRDYPGPG

TPSG1

186

Q9NRR2
HCYPFSGRERDEAGP

TINAGL1

291

Q9GZM7
PYAGPQVFRCAAARG

SIGLEC15

86

Q6ZMC9
TAGIFDAYVPPEGDA

MRPL45

81

Q9BRJ2
DDGPYSGPFCGRARV

SAMSN1

156

Q9NSI8
CEAGFYVDAGPPTHA

PELI2

351

Q9HAT8
LEFSYPAPACGEVDR

SLC5A9

506

Q2M3M2
CPGGAVREDTYPVGT

TBC1D3L

416

B9A6J9
GPDGRARPSDQVFCY

KBTBD11

371

O94819
YVPRGAEADCVSFPN

SLC28A2

586

O43868
TVYEDSGPGRPLSCF

SMURF1

161

Q9HCE7
AEVRLTPPGSCGFYD

STK36

836

Q9NRP7
AGPCPSLGEAYARET

APOBR

711

Q0VD83
CPGGAVREDTYPVGT

TBC1D3B

416

A6NDS4
CPGGAVREDTYPVGT

TBC1D3H

416

P0C7X1
RTEDDPEVGGPCYTL

TULP4

446

Q9NRJ4
EPGFSYSEEVCRCVP

VEGFC

396

P49767
CSPCAPIIGEYAGEV

TSPAN13

151

O95857
CPGGAVREDTYPVGT

TBC1D3F

416

A6NER0
VARYVCQEGFESPGG

SUSD1

261

Q6UWL2
SDRRNCGYPGISPEE

TFF2

86

Q03403
VAEFPHGYGSCDEIP

PXDN

1291

Q92626
GYAGADCSREICPVP

TNC

241

P24821
TEVCGYDIASPNAGP

TPP2

611

P29144
DDECAFYTSRAPPSG

TROAP

731

Q12815
GEEDPDRYVCSGVPG

PSEN2

56

P49810
CPGGAVREDTYPVGT

TBC1D3E

416

A0A087X179
RAGYRIDGEPCPGQF

PKHD1L1

3431

Q86WI1
GFRATVYPCPEPAVE

ATP6V0A4

241

Q9HBG4
TGERPYTCPECGKAF

ZNF835

441

Q9Y2P0
CPGGAVREDTYPVGT

TBC1D3D

416

A0A087WVF3
PYLCPECGAGFTEVA

ZNF629

841

Q9UEG4
FPVSEGKVDPYRSCG

PRSS50

91

Q9UI38
CPGGAVREDTYPVGT

TBC1D3G

416

Q6DHY5
CPGGAVREDTYPVGT

TBC1D3

416

Q8IZP1
VSPGYVPACRAEDGG

TG

1161

P01266
GEKPYVCPECGRAFS

ZNF71

266

Q9NQZ8
VPFYVRGPNVEAGCL

SULF2

341

Q8IWU5
CPGGAVREDTYPVGT

TBC1D3K

416

A0A087X1G2
FSTPCPGGAVREDTY

USP6

411

P35125
GSRPVAFSVDPCEEY

ZRANB1

126

Q9UGI0
CPGGAVREDTYPVGT

TBC1D3I

416

A0A087WXS9
CPGGAVREDTYPVGT

TBC1D3C

416

Q6IPX1
AVYRCGPPGTEASSD

TYK2

121

P29597
AEGEPCYIRDSGVAP

TYK2

286

P29597
YARGVDPPPCDAGTD

TM7SF3

171

Q9NS93
PREGPYVCSDSGKFT

ZNF776

231

Q68DI1
YDGAGRPQRCLPVFE

LAMC3

26

Q9Y6N6
CQEGFYGSALAPRPA

LAMC3

846

Q9Y6N6
DGDDNPVCRLPGYRA

LRRCC1

171

Q9C099
FYAETCPAPERGGAV

MYO1C

156

O00159
DGCFSTPEERAQGYP

NAGA

156

P17050
TGERPYACPECGKAF

MZF1

676

P28698
SPVGYNRCLADGREP

GRIN2B

581

Q13224