Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponenteukaryotic translation initiation factor 2 complex

EIF2S3 EIF2S3B

1.46e-046662GO:0005850
GeneOntologyCellularComponentintraciliary transport particle A

WDR19 TTC21A

2.72e-048662GO:0030991
HumanPhenoAbnormal lip morphology

WDR19 CACNA1C ORC4 FLNA PPP2R5D NALCN EIF2S3 SYNE1 VPS35L NAGA ABCC9 ENG UNC80 PHF21A

2.23e-0512492014HP:0000159
HumanPhenoIrregularly shaped sperm tail

WDR19 FSIP2 TTC21A

2.29e-0515203HP:0033393
HumanPhenoAbnormal distal phalanx morphology of finger

WDR19 FLNA NALCN VPS35L ABCC9 UNC80

3.79e-05174206HP:0009832
HumanPhenoAbnormal upper lip morphology

WDR19 CACNA1C ORC4 FLNA PPP2R5D NALCN EIF2S3 SYNE1 VPS35L ABCC9 UNC80 PHF21A

6.57e-059802012HP:0000177
HumanPhenoNeonatal hypotonia

WDR19 FLNA PPP2R5D NALCN SYNE1 UNC80

8.78e-05202206HP:0001319
HumanPhenoNonprogressive encephalopathy

MED23 UNC80

1.45e-045202HP:0007030
HumanPhenoAbnormality of the philtrum

WDR19 ORC4 FLNA PPP2R5D NALCN EIF2S3 SYNE1 ABCC9 UNC80 PHF21A

1.55e-047262010HP:0000288
HumanPhenoDepressed nasal tip

FLNA EIF2S3 PHF21A

1.59e-0428203HP:0000437
HumanPhenoAbsent sperm flagella

WDR19 FSIP2 TTC21A

1.59e-0428203HP:0032558
HumanPhenoThin upper lip vermilion

WDR19 CACNA1C PPP2R5D NALCN VPS35L ABCC9 UNC80

1.98e-04339207HP:0000219
HumanPhenoThin lips

WDR19 CACNA1C PPP2R5D NALCN VPS35L ABCC9 UNC80

1.98e-04339207HP:0000213
HumanPhenoEnlarged naris

NALCN UNC80

2.18e-046202HP:0009931
HumanPhenoTapered distal phalanges of finger

NALCN UNC80

2.18e-046202HP:0009884
HumanPhenoOral cavity telangiectasia

NAGA ENG

2.18e-046202HP:0000228
HumanPhenoLip telangiectasia

NAGA ENG

2.18e-046202HP:0000214
HumanPhenoTelangiectasia of the oral mucosa

NAGA ENG

2.18e-046202HP:0007428
HumanPhenoCoiled sperm flagella

WDR19 FSIP2 TTC21A

2.39e-0432203HP:0032560
HumanPhenoShort sperm flagella

WDR19 FSIP2 TTC21A

2.62e-0433203HP:0032559
HumanPhenoFlexion contracture of digit

CACNA1C ORC4 FLNA PPP2R5D NALCN SYNE1 GNRHR

2.98e-04362207HP:0030044
HumanPhenoAbsent sperm axoneme central pair complex

WDR19 FSIP2

3.04e-047202HP:0033525
HumanPhenoConspicuously happy disposition

NALCN UNC80

3.04e-047202HP:0100024
HumanPhenoProminent forehead

FLNA PPP2R5D NALCN VPS35L ABCC9 UNC80

3.60e-04261206HP:0011220
HumanPhenoLimited elbow movement

FLNA NALCN SYNE1 ABCC9 UNC80

3.81e-04168205HP:0002996
HumanPhenoShort hallux

FLNA VPS35L ABCC9

4.00e-0438203HP:0010109
HumanPhenoAbnormal sperm axoneme morphology

WDR19 FSIP2

4.04e-048202HP:0033524
HumanPhenoElbow flexion contracture

FLNA NALCN SYNE1 UNC80

4.74e-0497204HP:0002987
HumanPhenoHyperesthesia

NALCN UNC80

5.19e-049202HP:0100963
HumanPhenoAbnormality of the elbow

ORC4 FLNA NALCN SYNE1 ABCC9 UNC80

5.47e-04282206HP:0009811
HumanPhenoLower-limb joint contracture

ORC4 FLNA PPP2R5D NALCN SYNE1 ABCC9 UNC80

5.76e-04403207HP:0005750
HumanPhenoAbnormal sperm tail morphology

WDR19 FSIP2 TTC21A

5.78e-0443203HP:0012868
HumanPhenoAplasia/Hypoplasia of the hallux

FLNA VPS35L ABCC9

5.78e-0443203HP:0008362
HumanPhenoSmooth philtrum

WDR19 ORC4 FLNA NALCN UNC80

5.95e-04185205HP:0000319
HumanPhenoAbnormal nasal bridge morphology

WDR19 CACNA1C FLNA NALCN SYNE1 VPS35L NAGA ABCC9 GNRHR UNC80 PHF21A

6.00e-0410292011HP:0000422
HumanPhenoAbnormality of mouth shape

CACNA1C PPP2R5D NALCN EIF2S3 UNC80 PHF21A

6.83e-04294206HP:0011338
HumanPhenoElbow contracture

FLNA NALCN SYNE1 UNC80

7.38e-04109204HP:0034391
DomainSecretoglobin_1C1/2

SCGB1C2 SCGB1C1

1.05e-052612IPR028659
DomainSCGB

SCGB1C2 SCGB1C1

3.72e-049612PS51311
DomainUteroglobin

SCGB1C2 SCGB1C1

4.64e-0410612PF01099
DomainABC_TRANSPORTER_2

ABCC3 ABCA6 ABCC9

5.16e-0448613PS50893
DomainABC_tran

ABCC3 ABCA6 ABCC9

5.16e-0448613PF00005
DomainHEAT

IPO5 RANBP6 HEATR1

5.16e-0448613PF02985
DomainABC_TRANSPORTER_1

ABCC3 ABCA6 ABCC9

5.49e-0449613PS00211
DomainSecretoglobin

SCGB1C2 SCGB1C1

5.66e-0411612IPR016126
DomainABC_transporter-like

ABCC3 ABCA6 ABCC9

5.82e-0450613IPR003439
DomainHEAT

IPO5 RANBP6 HEATR1

9.00e-0458613IPR000357
DomainAAA+_ATPase

ORC4 ABCC3 ABCA6 ABCC9

1.26e-03144614IPR003593
DomainAAA

ORC4 ABCC3 ABCA6 ABCC9

1.26e-03144614SM00382
DomainHEAT_REPEAT

IPO5 RANBP6 HEATR1

1.55e-0370613PS50077
DomainActinin_actin-bd_CS

FLNA SYNE1

2.54e-0323612IPR001589
DomainACTININ_2

FLNA SYNE1

2.54e-0323612PS00020
DomainACTININ_1

FLNA SYNE1

2.54e-0323612PS00019
DomainABC_membrane

ABCC3 ABCC9

2.77e-0324612PF00664
DomainABC_TM1F

ABCC3 ABCC9

3.76e-0328612PS50929
DomainABC1_TM_dom

ABCC3 ABCC9

3.76e-0328612IPR011527
DomainG_PROTEIN_RECEP_F2_1

GPR157 GLP2R

7.56e-0340612PS00649
DomainG_PROTEIN_RECEP_F2_3

GPR157 GLP2R

7.56e-0340612PS50227
DomainGPCR_2_extracellular_dom

GPR157 GLP2R

7.56e-0340612IPR001879
DomainABC_transporter_CS

ABCC3 ABCC9

8.31e-0342612IPR017871
DomainG_PROTEIN_RECEP_F2_2

GPR157 GLP2R

1.16e-0250612PS00650
Domain7tm_2

GPR157 GLP2R

1.16e-0250612PF00002
DomainARM-like

IPO5 DOCK10 RANBP6 HEATR1

1.17e-02270614IPR011989
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC3 ABCA6 EIF2S3 ABCC9 EIF2S3B

1.68e-0599465MM14986
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCC3 NALCN ABCA6 EIF2S3 NIPAL2 SLC38A5 ABCC9 EIF2S3B UNC80

3.00e-04681469MM14985
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC3 ABCA6 EIF2S3 ABCC9

3.47e-04103464M758
PathwayREACTOME_RECYCLING_OF_EIF2_GDP

EIF2S3 EIF2S3B

3.70e-049462MM15418
PathwayKEGG_ABC_TRANSPORTERS

ABCC3 ABCA6 ABCC9

3.92e-0444463M11911
PathwayBIOCARTA_EIF2_PATHWAY

EIF2S3 EIF2S3B

4.61e-0410462MM1469
PathwayREACTOME_CELLULAR_RESPONSE_TO_MITOCHONDRIAL_STRESS

EIF2S3 EIF2S3B

4.61e-0410462MM17234
PathwayBIOCARTA_EIF_PATHWAY

EIF2S3 EIF2S3B

4.61e-0410462MM1394
PathwayREACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR

EIF2S3 EIF2S3B

6.73e-0412462MM14981
Pubmed

SCGB1C1 Plays a Critical Role in Suppression of Allergic Airway Inflammation through the Induction of Regulatory T Cell Expansion.

SCGB1C2 SCGB1C1

3.66e-06267238892470
Pubmed

Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80.

NALCN UNC80

3.66e-06267219092807
Pubmed

Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit.

ABCC9 MED23

3.66e-06267211934987
Pubmed

UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN.

NALCN UNC80

3.66e-06267226545877
Pubmed

The sodium leak channel, NALCN, in health and disease.

NALCN UNC80

3.66e-06267224904279
Pubmed

Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.

CACNA1C SYNE1

3.66e-06267227620326
Pubmed

Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain.

EIF2S3 EIF2S3B

3.66e-06267216325480
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

VMP1 ORC4 ACAD11 ZNF277 CNOT10 EIF2S3 SYNE1 CDK11A ICE1 HEATR1 UNC93B1 MED23 LIN9

4.79e-061497671331527615
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

NALCN UNC80

1.10e-05367226708753
Pubmed

UNC80 functions as a scaffold for Src kinases in NALCN channel function.

NALCN UNC80

1.10e-05367219535918
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

NALCN UNC80

1.10e-05367230167850
Pubmed

The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis.

CDK11A COPS6

1.10e-05367212446680
Pubmed

Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.

NALCN UNC80

1.10e-05367221040849
Pubmed

Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

NALCN UNC80

1.10e-05367232620897
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

CASP12 FLNA EIF2S3 SYNE1 EIF2S3B HEATR1 MUC13 MED23 TMEM109

1.40e-0575467935906200
Pubmed

Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.

EIF2S3 EIF2S3B

2.19e-05467231836389
Pubmed

The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.

NALCN UNC80

2.19e-05467232494638
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

IPO5 FLNA PPP2R5D EIF2S3 SYNE1 CYP4X1 EIF2S3B TMEM109 MAP3K2

2.30e-0580367936517590
Pubmed

Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.

SCGB1C2 SCGB1C1

3.64e-05567212406855
Pubmed

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.

EIF2S3 EIF2S3B

7.63e-05767215669143
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IPO5 VMP1 FLNA EIF2S3 VPS35L RANBP6 PNRC1 HEATR1 UNC93B1 MUC13 TMEM109

8.99e-051440671130833792
Pubmed

Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution.

EIF2S3 EIF2S3B

1.30e-0496729736774
Pubmed

The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development.

ABCC3 ABCC9

1.30e-04967233490088
Pubmed

Wnt pathway anomalies in developing amygdalae of Turner syndrome-like mice.

EIF2S3 EIF2S3B

1.30e-04967217873295
Pubmed

A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.

FLNA LIN9

1.63e-041067218548008
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

CACNA1C SYNE1

1.99e-041167220351715
Pubmed

Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.

EIF2S3 EIF2S3B

2.38e-041267223210685
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

IPO5 VMP1 FLNA EIF2S3 RANBP6 HEATR1 TMEM109

2.71e-0465767736180527
Pubmed

Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos.

CASP12 BID

3.78e-041567210377054
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

EIF2S3 EIF2S3B

3.78e-041567214762062
Pubmed

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.

EIF2S3 ICE1

4.31e-041667234270554
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

IGSF10 VMP1 ABCC3 NAGA SLC38A5 RANBP6 UNC93B1 TMEM109 ENG

4.79e-04120167935696571
Pubmed

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.

IPO5 FLNA EIF2S3 ABCC9

5.26e-0419267432176739
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

EIF2S3 EIF2S3B

5.48e-041867212023983
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

CACNA1C SYNE1

6.12e-041967218711365
Pubmed

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.

DENND10 VPS35L

6.12e-041967237172566
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

IPO5 FLNA LRRC31 ICE1

6.36e-0420267433005030
Pubmed

Emergence of young human genes after a burst of retroposition in primates.

EIF2S3 EIF2S3B

6.79e-042067216201836
Pubmed

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics.

EIF2S3 RANBP6 EIF2S3B

7.83e-049367325211037
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCA6

8.24e-04226728894702
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

WDR19 MED23 PHF21A

9.39e-049967334161765
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

WDR19 PPP2R5D CNOT10 TTC21A CDK11A HEATR1 COPS6 PHF21A MAP3K2

9.44e-04132167927173435
Pubmed

Brugada Syndrome

CACNA1C ABCC9

9.82e-042467220301690
Pubmed

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.

CACNA1C SYNE1

1.07e-032567238877142
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCC3 SLC38A5 ABCC9

1.11e-0310567330280653
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

IPO5 FLNA EIF2S3 RANBP6 HEATR1

1.15e-0340867533766124
Pubmed

No death without life: vital functions of apoptotic effectors.

CASP12 BID

1.15e-032667218309324
Pubmed

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.

PPP2R5D COPS6

1.15e-032667211531413
Pubmed

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

VPS26B TBC1D17

1.24e-032767222354992
Pubmed

An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia.

IPO5 NALCN

1.44e-032967211991713
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNA EIF2S3 HEATR1 MUC13

1.53e-0325667433397691
Pubmed

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.

FLNA EIF2S3 EIF2S3B

1.71e-0312267329530978
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

FLNA EIF2S3 EIF2S3B

1.92e-0312767330335684
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC9

3.85e-0413412807
GeneFamilySecretoglobins

SCGB1C2 SCGB1C1

4.49e-0414412734
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

WDR19 TTC21A

1.34e-0324412615
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_DN

IPO5 PPP2R5D SYNE1 DOCK10 MED23 MAP3K2

1.21e-05199676M8259
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1

IGSF10 CACNA1C DOCK10 NIPAL2 SLC38A5 ABCC9 TBC1D17

9.57e-06265607Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#2

IGSF10 CACNA1C DOCK10 NIPAL2 ABCC9 TBC1D17

1.66e-04290606Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

IGSF10 CACNA1C ACAD11 SYNE1 DOCK10 NIPAL2 ABCC9 PHF21A TBC1D17

1.89e-04726609Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4

IGSF10 CACNA1C ACAD11 SYNE1 DOCK10 NIPAL2 ABCC9 PHF21A TBC1D17

1.98e-04731609Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

IGSF10 CACNA1C ACAD11 SYNE1 DOCK10 NIPAL2 ABCC9 PHF21A TBC1D17

2.05e-04734609Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

IGSF10 CACNA1C SYNE1 DOCK10 NIPAL2 SLC38A5 ABCC9 PHF21A TBC1D17

2.26e-04744609Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

IGSF10 CACNA1C SYNE1 DOCK10 NIPAL2 ABCC9 PHF21A TBC1D17

2.46e-04591608Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

ARHGAP42 IGSF10 CASP12 ABCA6 ABCC9 ENG RYK

2.51e-04445607GSM777043_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2

IGSF10 CACNA1C SYNE1 DOCK10 NIPAL2 ABCC9 PHF21A TBC1D17

2.94e-04607608Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#2

IGSF10 CACNA1C DOCK10 NIPAL2 ABCC9 TBC1D17

3.33e-04330606Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 TEDDM1 NIPAL2 SAMD3 ENG

3.89e-061596655ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 TEDDM1 NIPAL2 SAMD3 ENG

5.39e-06170665876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 TEDDM1 NIPAL2 SAMD3 ENG

5.39e-061706651f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 SYNE1 DOCK10 SAMD3 ENG

5.70e-0617266508a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 SYNE1 DOCK10 SAMD3 ENG

5.70e-06172665553701349444eb366df3c11f54bb093434f153c6
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ARHGAP42 CACNA1C NIPAL2 SAMD3 ENG

6.92e-06179665342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 NIPAL2 SAMD3 ENG

8.55e-0618766515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 NIPAL2 SAMD3 ENG

8.55e-06187665f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 NIPAL2 SAMD3 ENG

8.78e-0618866532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157 SYNE1

1.02e-0519466560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 IGSF10 CACNA1C ABCA6 SYNE1

1.02e-051946656e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellremission-Non-classical_Monocyte|remission / disease stage, cell group and cell class

ABCC3 DENND10 NAGA UNC93B1 BID

1.07e-05196665049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 FLNA NALCN ABCA6 ABCC9

1.10e-0519766580e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IGSF10 CACNA1C ABCC3 ABCA6 DOCK10

1.10e-051976650034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellremission-Non-classical_Monocyte|World / disease stage, cell group and cell class

ABCC3 DENND10 NAGA UNC93B1 BID

1.13e-051986651c170655070acca00520b7cf9c510a04c0a90a8f
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 DOCK10 CYP4X1 ABCC9 ENG

1.13e-0519866572aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA NALCN SYNE1 ABCC9

1.18e-05200665593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

CACNA1C CASP12 ABCA6 ABCC9

6.39e-05145664ffbdadea0185e5d3b85f2868d5ec82b50cf2e2a1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLNA DOCK10 ENG MAP3K2

9.35e-051606646ed37d1fd0304932319d6b942502404115ff36a7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DOCK10 SAMD3 ENG

1.03e-04164664f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA1C DCHS2 ACAD11 SYNE1

1.18e-04170664f0b0d2d0402de3ed7322284a599646db43475761
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CACNA1C DCHS2 ACAD11 SYNE1

1.18e-04170664054360a3b05f5e41221c98b122d241b1affad26a
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP42 DCHS2 CYP4X1 ABCC9

1.21e-04171664a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNE1 RANBP6 EIF2S3B SAMD3

1.24e-04172664f3c16a62eba1ed190318beee131c71c5150b266a
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR19 ARHGAP42 MUC13 UNC80

1.29e-04174664a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 SYNE1 NIPAL2 ENG

1.32e-0417566412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SYNE1 SAMD3 UNC80

1.35e-041766646b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.47e-0418066408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.47e-041806649b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VMP1 NIPAL2 UNC93B1 ENG

1.47e-041806646f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.50e-041816649e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 SYNE1 CYP4X1 ENG

1.50e-04181664a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C FLNA NALCN UNC80

1.50e-04181664d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 SYNE1 CYP4X1 ENG

1.50e-04181664526e858a848470b6d2d5248788004d9735ed3add
ToppCell390C-Myeloid-Dendritic-cDC1|390C / Donor, Lineage, Cell class and subclass (all cells)

GPR157 NAGA UNC93B1 BID

1.50e-04181664d1c69171600b2d2aec96fa86fa757b588c265f7c
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

ARHGAP42 CACNA1C ABCC9 ENG

1.54e-041826642075efeae633550fb2eb026d0dfd741c8252482e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.54e-0418266444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.54e-04182664d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellfacs-Lung-EPCAM-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA NAGA DOCK10 UNC93B1

1.57e-04183664f524501dec1dccbf44100a61395116e4525bdc89
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 FLNA NALCN ABCC9

1.57e-04183664667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCelldroplet-Marrow-nan-21m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP12 SAMD3 MUC13 ENG

1.60e-041846647e129862f8d2353387999e633725325c4d8cb42e
ToppCellmegakaryocytic|World / Lineage and Cell class

IGSF10 ABCC3 SCGB1C2 SCGB1C1

1.60e-04184664b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C ABCA6 ABCC9 GLP2R

1.63e-04185664a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 CACNA1C FLNA NALCN

1.67e-041866646add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCelldroplet-Marrow-BM-1m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IPO5 NAGA DOCK10 TMEM109

1.70e-04187664028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 FLNA NALCN ABCC9

1.74e-04188664b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.77e-0418966471397e993a77d70b2eeede240bdfc7660b558987
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C ABCA6 ABCC9 GNRHR

1.77e-04189664a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.77e-041896644eea4759520c312bd17a681034d8074e47093d2b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.77e-04189664a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.77e-04189664e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C ABCA6 ABCC9 GNRHR

1.77e-04189664381058f55908f84375b54601d617389ef43ab855
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 CACNA1C SYNE1 ABCC9

1.77e-041896647ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

EIF2S3 SYNE1 PNRC1 SAMD3

1.77e-041896640e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C ABCA6 ABCC9 GNRHR

1.77e-04189664302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 DCHS2 ABCA6 ABCC9

1.81e-041906642306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 DOCK10 CYP4X1 ABCC9

1.81e-0419066410125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 FLNA NALCN ABCC9

1.81e-041906645681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 DCHS2 ABCA6 ABCC9

1.81e-041906641f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.81e-04190664841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.85e-04191664a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.85e-04191664b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ARHGAP42 CACNA1C FLNA ABCC9

1.85e-04191664fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 NALCN SYNE1 ABCC9

1.85e-0419166408042952431ca1a6fd7dfc13f36eb28643979598
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 CACNA1C SYNE1 ABCC9

1.85e-041916647853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NALCN ABCA6 ABCC9

1.85e-041916648f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 DCHS2 ABCA6 ABCC9

1.88e-041926649093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.88e-041926646f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 FLNA NALCN ABCC9

1.88e-0419266424e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 DCHS2 ABCA6 ABCC9

1.88e-041926649ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.88e-04192664dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 IGSF10 CACNA1C ABCA6

1.88e-041926643d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.88e-04192664deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 NALCN ABCA6 ABCC9

1.92e-04193664f1199518c3626fd29bfce65070dd21a660671213
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGSF10 ABCA6 NAGA GLP2R

1.92e-041936647c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF10 CACNA1C ABCA6 GPR157

1.92e-04193664fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CACNA1C FLNA NALCN SLC38A5

1.92e-041936645896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSIP2 ABCC3 LRRC31 MUC13

1.96e-0419466449cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSIP2 ABCC3 LRRC31 MUC13

1.96e-04194664fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IGSF10 ABCA6 NIPAL2 GLP2R

1.96e-04194664439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NALCN ABCA6 ABCC9 ENG

1.96e-04194664e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNA SYNE1 SAMD3 TMEM109

2.00e-04195664003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NALCN ABCA6 ABCC9

2.00e-04195664edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP42 CACNA1C ABCA6 ABCC9

2.00e-041956643d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 NALCN ABCA6 ABCC9

2.04e-041966642b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NALCN ABCC9 SAMD3

2.04e-04196664fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NALCN ABCC9 SAMD3

2.04e-04196664802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGSF10 VMP1 ABCC3 FLNA

2.04e-04196664b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 CDK11A MED23 C3orf20

2.08e-0419766457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellMacrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

NAGA UNC93B1 ENG BID

2.08e-04197664598fb7a9a8400af49d90807b3155d3cc1c34f505
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 CACNA1C ABCA6 DOCK10

2.08e-0419766473a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGSF10 CACNA1C ABCA6 SLC38A5

2.12e-04198664f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF10 CASP12 ABCA6 SLC38A5

2.16e-041996647f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF10 CASP12 ABCA6 SLC38A5

2.16e-04199664301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF10 CASP12 ABCA6 SLC38A5

2.16e-041996649a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGSF10 CACNA1C ABCA6 SLC38A5

2.16e-0419966466a79732caf2f04c09b4d9832377aa01ca477677
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND10 NAGA UNC93B1 BID

2.16e-04199664df946601b295be5419c09befbfa73f4314eef116
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGSF10 ABCC3 ABCA6 SLC38A5

2.16e-041996646bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C ABCA6 ABCC9 ENG

2.16e-041996649503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGSF10 ABCA6 ABCC9 GLP2R

2.20e-042006640b2614b8513693dd508c9003699049efd9abac52
DiseaseMEHMO syndrome (implicated_via_orthology)

EIF2S3 EIF2S3B

4.34e-062622DOID:0060801 (implicated_via_orthology)
Diseasehypopituitarism (implicated_via_orthology)

EIF2S3 EIF2S3B

6.48e-056622DOID:9406 (implicated_via_orthology)
Diseaseleukodystrophy (implicated_via_orthology)

EIF2S3 EIF2S3B

1.55e-049622DOID:10579 (implicated_via_orthology)
DiseaseShortened QT interval

CACNA1C ABCC9

2.36e-0411622C0151879
DiseaseHypogonadism

EIF2S3 GNRHR

5.11e-0416622C0020619
DiseaseBrugada Syndrome (disorder)

CACNA1C ABCC9

1.16e-0324622C1142166
Diseaseglucose metabolism disease (implicated_via_orthology)

EIF2S3 EIF2S3B

1.59e-0328622DOID:4194 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VILHTALMLKKRIVV

DENND10P1

171

Q6NSW5
KVSDIMLQKLKSLHL

CAGE1

646

Q8TC20
SAIKMLHSRVKLILE

COPS6

226

Q7L5N1
LVALVFLMSVLLKKA

ABCA6

311

Q8N139
MFLIRVLLPLHKVKS

PPP2R5D

321

Q14738
LMIFSKLLKHSVIVA

ABCC9

996

O60706
LVHMVKLLIKTFLDG

CASP12

11

Q6UXS9
DAMTLVLKKELVAHL

ENG

366

P17813
IEKIRLLTLKAAHSM

ACAD11

681

Q709F0
KLNLILVLSLSTMHV

NPS

6

P0C0P6
LSHLSKLKMVLGVLL

ABCC3

66

O15438
LSVLEICLIIAMKHL

ORC4

321

O43929
VTRLSKILMIKKEHI

LIN9

346

Q5TKA1
VIKLINEIMSIISKH

FSIP2

4826

Q5CZC0
NRELMAVHLKTLLKV

PNRC1

311

Q12796
IKTKEIHGAIVRMLL

OR51J1

296

Q9H342
LLSITQQMHLVSKLK

LRRC31

131

Q6UY01
LDRSIHMKSLKILLV

MAP3K2

106

Q9Y2U5
KMSLIHSIATRVIKL

MED23

536

Q9ULK4
MHSSLEKVKQLIRLI

PHF21A

611

Q96BD5
HTKQAGLVVKLLMKL

KRIT1

711

O00522
VKHLHSIMVLKLQEL

IPO5

486

O00410
KALILMNSKHTHLIL

PPP4R3C

541

Q6ZMV5
ILIVMILRHKQKDTI

DCHS2

3011

Q6V1P9
LILMHVSLRLKPAKI

IGSF10

2026

Q6WRI0
LHSILSELKIQKISM

ICE1

1971

Q9Y2F5
ILKLLISKLKAHQMC

GLP2R

361

O95838
IIKAMVPLLHIALLV

CACNA1C

261

Q13936
VRHLALAVLKNLMAK

DOCK10

1171

Q96BY6
MKLLLKHLTLANLLE

GNRHR

76

P30968
KHLTLANLLETLIVM

GNRHR

81

P30968
RLIALLEVLSQKKMH

FLNA

76

P21333
SIHLLTELLRLKMKA

C3orf20

141

Q8ND61
MIELKVTIALILLHF

CYP4X1

461

Q8N118
LLRHSSMADKKLVLI

GPR157

216

Q5UAW9
EVKTLMIQLLRGVKH

CDK11A

526

Q9UQ88
KTMLVLALLLAKKVA

BID

146

P55957
MKKVLLLITAILAVA

FDCSP

1

Q8NFU4
RVLMKLFIKVHLEDV

HEATR1

846

Q9H583
AIEIMKLKHILILQN

EIF2S3B

176

Q2VIR3
VILHTALMLKKRIVV

DENND10

171

Q8TCE6
ILAVLHLHSMKRIEL

RYK

246

P34925
AHVKAMKVLISFIIL

TAS2R10

221

Q9NYW0
HMVGQLKILLKSVLD

SYNE1

7116

Q8NF91
LIIYELLLLMVSHVK

TEDDM1

106

Q5T9Z0
EMLDILIKHLVKVSL

ARHGAP42

506

A6NI28
IVSVLIILPLALMKH

SLC38A5

176

Q8WUX1
LVKKIGHQAVLMDLI

SAMD3

46

Q8N6K7
KHMVILLTLVAILAS

NIPAL2

206

Q9H841
MHKAELVKLLVQVLG

SCGB1C2

76

P0DMR2
LMILHSYILVKIHVK

WDR19

1151

Q8NEZ3
DSMVKNLHSVLVIKL

RANBP6

491

O60518
EKALHLLAVLEKMIS

CNOT10

166

Q9H9A5
LLVRIKIKHMEIDII

VPS26B

196

Q4G0F5
ILKHINELTMKLSVE

TBC1D17

551

Q9HA65
LHMKAKLAVLLVTLV

UNC93B1

491

Q9H1C4
TVMAQILEHLKTLAK

VPS35L

866

Q7Z3J2
HRLALTMLIKIVKSL

UNC80

786

Q8N2C7
MKAIIHLTLLALLSV

MUC13

1

Q9H3R2
MHKAELVKLLVQVLG

SCGB1C1

76

Q8TD33
VLIFLQALLMSRKHK

TTC21A

406

Q8NDW8
GKHVFKAILMVLVAL

TMEM109

11

Q9BVC6
KAILMVLVALILLHS

TMEM109

16

Q9BVC6
LKHMIIEHKIVIADV

ZNF277

76

Q9NRM2
MDLLKISHTKLHLLE

YIPF7

1

Q8N8F6
KAIIKMHIQKIFVII

VMP1

296

Q96GC9
AIEIMKLKHILILQN

EIF2S3

176

P41091
GKHVTLKMLLLTVVV

NALCN

1316

Q8IZF0
MLLKTVLLLGHVAQV

NAGA

1

P17050