Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidase activity	PAPPA2 ADAMTS19 USP40 OTUD7A ADAMTS16 ADAMTS18 PCSK7 ADAMTS8 ESPL1 PRSS36	3.44e-06	654	49	10	GO:0008233
GeneOntologyMolecularFunction	endopeptidase activity	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 PCSK7 ADAMTS8 ESPL1 PRSS36	9.02e-06	430	49	8	GO:0004175
GeneOntologyMolecularFunction	metalloendopeptidase activity	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	1.11e-05	120	49	5	GO:0004222
GeneOntologyMolecularFunction	metallopeptidase activity	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	1.28e-04	200	49	5	GO:0008237
GeneOntologyMolecularFunction	collagen binding	VWF MRC2 USH2A	1.04e-03	81	49	3	GO:0005518
GeneOntologyCellularComponent	extracellular matrix	ADAMTS19 VWF ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 DMBT1 USH2A SSPOP	2.21e-05	656	50	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS19 VWF ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 DMBT1 USH2A SSPOP	2.27e-05	658	50	9	GO:0030312
GeneOntologyCellularComponent	ciliary transition zone	SPTBN5 RP1L1 USH2A TCTN2	4.21e-05	81	50	4	GO:0035869
GeneOntologyCellularComponent	membrane attack complex	C6 C8B	1.17e-04	7	50	2	GO:0005579
GeneOntologyCellularComponent	photoreceptor connecting cilium	SPTBN5 RP1L1 USH2A	2.06e-04	48	50	3	GO:0032391
GeneOntologyCellularComponent	collagen-containing extracellular matrix	VWF ADAMTSL5 ADAMTS8 DMBT1 USH2A SSPOP	1.59e-03	530	50	6	GO:0062023
GeneOntologyCellularComponent	pore complex	C6 C8B	1.76e-03	26	50	2	GO:0046930
Domain	TSP_1	ADAMTS19 THSD7A ADAMTSL5 ISM1 ADAMTS16 ADAMTS18 ADAMTS8 C6 C8B SSPOP UNC5D	8.64e-18	63	50	11	PF00090
Domain	TSP1	ADAMTS19 THSD7A ADAMTSL5 ISM1 ADAMTS16 ADAMTS18 ADAMTS8 C6 C8B SSPOP UNC5D	1.25e-17	65	50	11	SM00209
Domain	TSP1_rpt	ADAMTS19 THSD7A ADAMTSL5 ISM1 ADAMTS16 ADAMTS18 ADAMTS8 C6 C8B SSPOP UNC5D	1.25e-17	65	50	11	IPR000884
Domain	TSP1	ADAMTS19 THSD7A ADAMTSL5 ISM1 ADAMTS16 ADAMTS18 ADAMTS8 C6 C8B SSPOP UNC5D	1.25e-17	65	50	11	PS50092
Domain	ADAM_spacer1	ADAMTS19 ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8	3.63e-09	23	50	5	IPR010294
Domain	ADAM_spacer1	ADAMTS19 ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8	3.63e-09	23	50	5	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8	4.58e-09	24	50	5	IPR013273
Domain	MetalloPept_cat_dom	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	2.46e-06	81	50	5	IPR024079
Domain	-	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	2.46e-06	81	50	5	3.40.390.10
Domain	Peptidase_M12B_N	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.49e-06	39	50	4	IPR002870
Domain	Pep_M12B_propep	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.49e-06	39	50	4	PF01562
Domain	DISINTEGRIN_1	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.87e-06	40	50	4	PS00427
Domain	Reprolysin	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.87e-06	40	50	4	PF01421
Domain	ADAM_MEPRO	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.87e-06	40	50	4	PS50215
Domain	DISINTEGRIN_2	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.87e-06	40	50	4	PS50214
Domain	Peptidase_M12B	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	3.87e-06	40	50	4	IPR001590
Domain	Disintegrin_dom	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	4.28e-06	41	50	4	IPR001762
Domain	ZINC_PROTEASE	PAPPA2 ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	6.31e-06	98	50	5	PS00142
Domain	PLAC	ADAMTS19 ADAMTS16 ADAMTS18	6.44e-06	14	50	3	PF08686
Domain	PLAC	ADAMTS19 ADAMTS16 ADAMTS18	1.70e-05	19	50	3	PS50900
Domain	PLAC	ADAMTS19 ADAMTS16 ADAMTS18	1.70e-05	19	50	3	IPR010909
Domain	LamGL	PAPPA2 USH2A	4.20e-05	4	50	2	SM00560
Domain	LamG-like	PAPPA2 USH2A	4.20e-05	4	50	2	IPR006558
Domain	MACPF_CS	C6 C8B	1.05e-04	6	50	2	IPR020863
Domain	MACPF_2	C6 C8B	1.46e-04	7	50	2	PS51412
Domain	MACPF_1	C6 C8B	1.46e-04	7	50	2	PS00279
Domain	LDLR_class-A_CS	C6 C8B SSPOP	1.66e-04	40	50	3	IPR023415
Domain	CYSTEINE_SWITCH	ADAMTS19 ADAMTS16 ADAMTS18	1.79e-04	41	50	3	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS19 ADAMTS16 ADAMTS18	2.07e-04	43	50	3	IPR001818
Domain	Ldl_recept_a	C6 C8B SSPOP	2.37e-04	45	50	3	PF00057
Domain	LDLRA_1	C6 C8B SSPOP	2.87e-04	48	50	3	PS01209
Domain	LDLRA_2	C6 C8B SSPOP	3.05e-04	49	50	3	PS50068
Domain	LDrepeatLR_classA_rpt	C6 C8B SSPOP	3.05e-04	49	50	3	IPR002172
Domain	LDLa	C6 C8B SSPOP	3.05e-04	49	50	3	SM00192
Domain	MAC_perforin	C6 C8B	3.12e-04	10	50	2	IPR001862
Domain	MACPF	C6 C8B	3.80e-04	11	50	2	PF01823
Domain	TIL	VWF SSPOP	4.56e-04	12	50	2	PF01826
Domain	MACPF	C6 C8B	4.56e-04	12	50	2	SM00457
Domain	MACPF	C6 C8B	4.56e-04	12	50	2	IPR020864
Domain	C8	VWF SSPOP	4.56e-04	12	50	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF SSPOP	5.38e-04	13	50	2	IPR014853
Domain	C8	VWF SSPOP	5.38e-04	13	50	2	SM00832
Domain	TIL_dom	VWF SSPOP	6.26e-04	14	50	2	IPR002919
Domain	VWD	VWF SSPOP	8.23e-04	16	50	2	SM00216
Domain	VWF_type-D	VWF SSPOP	8.23e-04	16	50	2	IPR001846
Domain	VWFD	VWF SSPOP	8.23e-04	16	50	2	PS51233
Domain	VWD	VWF SSPOP	8.23e-04	16	50	2	PF00094
Domain	CTCK_1	VWF SSPOP	1.05e-03	18	50	2	PS01185
Domain	VWC_out	VWF SSPOP	1.17e-03	19	50	2	SM00215
Domain	SRCR	CD163L1 DMBT1	1.43e-03	21	50	2	PF00530
Domain	SR	CD163L1 DMBT1	2.03e-03	25	50	2	SM00202
Domain	-	CD163L1 DMBT1	2.03e-03	25	50	2	3.10.250.10
Domain	Cys_knot_C	VWF SSPOP	2.03e-03	25	50	2	IPR006207
Domain	CTCK_2	VWF SSPOP	2.03e-03	25	50	2	PS01225
Domain	-	PAPPA2 WDFY3 USH2A	2.10e-03	95	50	3	2.60.120.200
Domain	SRCR_1	CD163L1 DMBT1	2.19e-03	26	50	2	PS00420
Domain	SRCR_2	CD163L1 DMBT1	2.19e-03	26	50	2	PS50287
Domain	SRCR-like_dom	CD163L1 DMBT1	2.19e-03	26	50	2	IPR017448
Domain	ACR	ADAMTS19 ADAMTS8	2.36e-03	27	50	2	SM00608
Domain	ADAM_Cys-rich	ADAMTS19 ADAMTS8	2.36e-03	27	50	2	IPR006586
Domain	SRCR	CD163L1 DMBT1	2.36e-03	27	50	2	IPR001190
Domain	ConA-like_dom	PAPPA2 TRIM25 WDFY3 USH2A	2.78e-03	219	50	4	IPR013320
Domain	VWFC_1	VWF SSPOP	4.18e-03	36	50	2	PS01208
Domain	VWC	VWF SSPOP	4.64e-03	38	50	2	SM00214
Domain	VWFC_2	VWF SSPOP	4.64e-03	38	50	2	PS50184
Domain	EGF_1	C6 C8B USH2A SSPOP	4.78e-03	255	50	4	PS00022
Domain	VWF_dom	VWF SSPOP	5.65e-03	42	50	2	IPR001007
Domain	C-type_lectin_CS	MRC2 CLEC11A	5.91e-03	43	50	2	IPR018378
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	6.81e-12	39	37	7	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	6.81e-12	39	37	7	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	4.06e-10	68	37	7	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	1.16e-08	109	37	7	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	1.31e-08	111	37	7	M27416
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	7.61e-08	143	37	7	M27275
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS19 THSD7A ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8 SSPOP	3.32e-06	250	37	7	M27554
Pathway	KEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION	C6 C8B	1.40e-04	7	37	2	M47873
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C6 C8B	1.86e-04	8	37	2	MM14656
Pathway	REACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT	C6 C8B	1.86e-04	8	37	2	M27006
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION	C6 C8B	2.39e-04	9	37	2	M47881
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	SPTBN5 ADAMTS19 TRIM25 THSD7A ADAMTSL5 OTUD7A ADAMTS16 TMED7 ADAMTS18 FBXW2 ADAMTS8 SSPOP	2.52e-04	1475	37	12	M19806
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	SPTBN5 ADAMTS19 THSD7A ADAMTSL5 OTUD7A ADAMTS16 TMED7 ADAMTS18 FBXW2 ADAMTS8 SSPOP	6.23e-04	1389	37	11	MM15307
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	VWF C6 C8B	7.74e-04	69	37	3	M16894
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C6 C8B	8.89e-04	17	37	2	MM15944
Pathway	WP_COMPLEMENT_ACTIVATION	C6 C8B	1.50e-03	22	37	2	M39502
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS19 THSD7A ADAMTSL5 ISM1 ADAMTS16 ADAMTS18 ADAMTS8 C6 SSPOP	2.52e-15	75	53	9	20637190
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS19 ADAMTS16 ADAMTS18	1.16e-07	7	53	3	11867212
Pubmed	Evaluation of ADAMTS12, ADAMTS16, ADAMTS18 and IL-33 serum levels in pre-eclampsia.	ADAMTS16 ADAMTS18	2.28e-06	2	53	2	26382559
Pubmed	Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.	ADAMTS18 ADAMTS8	6.83e-06	3	53	2	28814085
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS19 ADAMTS16	1.36e-05	4	53	2	28088271
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS16 ADAMTS18	1.36e-05	4	53	2	16507336
Pubmed	The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.	C6 C8B	2.27e-05	5	53	2	10551839
Pubmed	Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.	C6 C8B	3.40e-05	6	53	2	22832194
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	PAPPA2 VWF NKX6-3 TRIM25 MRC2 CLEC11A	4.20e-05	419	53	6	28700943
Pubmed	CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.	C6 C8B	4.76e-05	7	53	2	30552328
Pubmed	Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.	C6 C8B	4.76e-05	7	53	2	19864026
Pubmed	Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.	CYB5D2 ADAMTS16	6.34e-05	8	53	2	24039173
Pubmed	Molecular organization and function of the complement system.	C6 C8B	6.34e-05	8	53	2	3052276
Pubmed	Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells.	C6 C8B	8.15e-05	9	53	2	19162005
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	ADAMTS16 ADAMTS18	2.05e-04	14	53	2	31242448
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	ADAMTS16 ADAMTS18	2.36e-04	15	53	2	7543410
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS16 ADAMTS18	2.70e-04	16	53	2	30579834
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	MRC2 ADAMTS16 ADAMTS8 DMBT1	3.00e-04	210	53	4	16537572
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 ITPRID2 WDFY3	3.24e-04	87	53	3	12465718
Pubmed	LncRNA SLC26A4-AS1 suppresses the MRN complex-mediated DNA repair signaling and thyroid cancer metastasis by destabilizing DDX5.	TRIM25 MRC2	4.70e-04	21	53	2	32939012
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	THSD7A DLGAP4 WDFY3	5.16e-04	102	53	3	10231032
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	USP40 SLC3A2	7.80e-04	27	53	2	34709416
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	MRC2 MAP3K11 WDFY3 SLC3A2	9.43e-04	285	53	4	34369648
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	SPTBN5 USP40 GEMIN4 UNC5D SLC3A2	9.44e-04	496	53	5	31343991
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C6 C8B	1.03e-03	31	53	2	19344414
Pubmed	OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.	USP40 OTUD7A	1.10e-03	32	53	2	33669244
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	C6 C8B	1.10e-03	32	53	2	18842294
Pubmed	MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.	PAPPA2 ADAMTS18	1.31e-03	35	53	2	22407321
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	ADAMTS16 ADAMTS18	1.47e-03	37	53	2	34323105
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	ZSWIM8 USP40 OTUD7A	1.48e-03	147	53	3	29576527
Interaction	ADAMTS19 interactions	ADAMTS19 ADAMTS16 ADAMTS18	1.35e-07	5	49	3	int:ADAMTS19
Cytoband	12p13.3	VWF CD163L1	5.57e-04	30	53	2	12p13.3
Cytoband	17q23.2	TRIM25 MRC2	6.75e-04	33	53	2	17q23.2
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS16 ADAMTS18 ADAMTS8	7.00e-08	19	39	4	50
GeneFamily	Complement system\|Sushi domain containing	C6 C8B	2.73e-03	36	39	2	492
GeneFamily	C-type lectin domain family	MRC2 CLEC11A	4.61e-03	47	39	2	494
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 C6	6.71e-03	57	39	2	1179
GeneFamily	WD repeat domain containing	WDR27 FBXW2 WDFY3	1.87e-02	262	39	3	362
Coexpression	NABA_MATRISOME	PAPPA2 ADAMTS19 VWF ADAMTSL5 TNFSF14 CLEC11A ISM1 ADAMTS16 ADAMTS18 ADAMTS8 DMBT1 USH2A SSPOP	9.22e-08	1026	53	13	M5889
Coexpression	NABA_MATRISOME	PAPPA2 ADAMTS19 VWF ADAMTSL5 TNFSF14 CLEC11A ISM1 ADAMTS16 ADAMTS18 ADAMTS8 DMBT1 SSPOP	6.09e-07	1008	53	12	MM17056
Coexpression	NABA_ECM_REGULATORS	PAPPA2 ADAMTS19 ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8	8.46e-06	238	53	6	M3468
Coexpression	NABA_ECM_REGULATORS	PAPPA2 ADAMTS19 ADAMTSL5 ADAMTS16 ADAMTS18 ADAMTS8	9.30e-06	242	53	6	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	PAPPA2 ADAMTS19 ADAMTSL5 TNFSF14 CLEC11A ISM1 ADAMTS16 ADAMTS18 ADAMTS8	1.55e-05	738	53	9	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	PAPPA2 ADAMTS19 ADAMTSL5 TNFSF14 CLEC11A ISM1 ADAMTS16 ADAMTS18 ADAMTS8	1.78e-05	751	53	9	M5885
Coexpression	DESCARTES_FETAL_CEREBELLUM_VASCULAR_ENDOTHELIAL_CELLS	SH3TC2 ADORA2A-AS1 VWF CLEC11A ISM1 NOSTRIN ERVMER34-1 SLC3A2	4.30e-05	645	53	8	M40158
Coexpression	GSE17721_12H_VS_24H_LPS_BMDC_UP	CNPPD1 ADAMTSL5 PCSK7 MAP3K11 SLC3A2	5.24e-05	200	53	5	M4081
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HENDO	ADORA2A-AS1 VWF ISM1 MAP3K11 ITPRID2 NOSTRIN ERVMER34-1 SLC3A2 CA5A	6.56e-05	888	53	9	M39049
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(Striatum,_dSPNs,_neurofilament_state+)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CD163L1 C6 C8B GPAT2	4.11e-07	51	53	4	1984936e6d7141b4ca6a2017af39aa41f9e7c959
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(Striatum,_dSPNs,_neurofilament_state+)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CD163L1 C6 C8B GPAT2	4.11e-07	51	53	4	e288e3551e75df98b901e0735bb9638fea81f82d
ToppCell	Serous\|World / shred by cell class for turbinate	ADAMTS19 ADAMTS18 DMBT1 NOSTRIN GPAT2	9.72e-07	150	53	5	6a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	VWF ISM1 NOSTRIN RTP4 CA5A	1.55e-06	165	53	5	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3TC2 ADAMTS16 WDFY3 NOSTRIN UNC5D	2.80e-06	186	53	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADORA2A-AS1 VWF NOSTRIN ERVMER34-1 CA5A	3.89e-06	199	53	5	1295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	THSD7A ADAMTSL5 TNFSF14 ADAMTS8	1.23e-05	119	53	4	6425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC2 TNFSF14 RTP4 CA5A	1.80e-05	131	53	4	419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN5 CNPPD1 ADAMTS16 USH2A	2.03e-05	135	53	4	88f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ISM1 NOSTRIN RTP4 CA5A	2.68e-05	145	53	4	37580218f6a6f65a1d827cbcf59465f8827f9a55
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADORA2A-AS1 VWF THSD7A ERVMER34-1	3.66e-05	157	53	4	275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CLEC11A CD163L1 ADAMTS18 NOSTRIN	3.75e-05	158	53	4	32c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	VWF NOSTRIN RTP4 CA5A	3.94e-05	160	53	4	04714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.03e-05	161	53	4	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.13e-05	162	53	4	0bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA5 DMBT1 USH2A UNC5D	4.13e-05	162	53	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.13e-05	162	53	4	5799a602ef8d83925907e8e34532428be7330228
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.34e-05	164	53	4	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.34e-05	164	53	4	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWF TRIM25 NOSTRIN CA5A	4.55e-05	166	53	4	27af6c906cff1d40d134f0386db7708869691121
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF THSD7A ADAMTS18 NOSTRIN	4.99e-05	170	53	4	1a568efcff9c39b3f709b55a05d24710450a2657
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF THSD7A ADAMTS18 NOSTRIN	4.99e-05	170	53	4	66d41d794790e621d72ac37af995510537103c9c
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	TRIM25 ADAMTSL5 OTUD7A PRSS36	5.22e-05	172	53	4	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	facs-Lung-Endomucin-24m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOSTRIN RTP4 SLC3A2	5.46e-05	174	53	4	ea27868d0373843a5137569ac3f9e3f8c92c7dcc
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOSTRIN RTP4 SLC3A2	5.58e-05	175	53	4	1c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	SPTBN5 VWF ITPRID2 NOSTRIN	5.83e-05	177	53	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CD163L1 RP1L1 PRSS36 CA5A	5.96e-05	178	53	4	24e8c62060455159235985f456af0c5023a7f3f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CD163L1 RP1L1 PRSS36 CA5A	5.96e-05	178	53	4	4f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD163L1 GEMIN4 WDR27 PRSS36	6.23e-05	180	53	4	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF NKX6-3 THSD7A ITPRID2	6.36e-05	181	53	4	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH3TC2 ADAMTS16 WDFY3 UNC5D	6.50e-05	182	53	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 ADAMTS18 NOSTRIN C8B	6.50e-05	182	53	4	5b2bad38c723cd64a7fe7f2dcd361708014c8cfe
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 ADAMTS18 NOSTRIN C8B	6.50e-05	182	53	4	de90bf587a73973a8b1458c9cd366c274b72ef9e
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF THSD7A RP1L1 ITPRID2	6.64e-05	183	53	4	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 USH2A SSPOP UNC5D	6.78e-05	184	53	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 USH2A SSPOP UNC5D	6.78e-05	184	53	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 USH2A SSPOP UNC5D	6.78e-05	184	53	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF THSD7A ISM1 NOSTRIN	6.78e-05	184	53	4	842473fa415575441b595073a994b6d621169776
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC2 CLEC11A ISM1 ADAMTS8	6.92e-05	185	53	4	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 ADAMTS18 NOSTRIN C8B	7.07e-05	186	53	4	16092819e9148dfe64f07c737652b6e533e699f7
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA2 THSD7A ABCA5 ADAMTS16	7.37e-05	188	53	4	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 ADAMTS18 NOSTRIN C8B	7.52e-05	189	53	4	ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 ADAMTS18 NOSTRIN C8B	7.68e-05	190	53	4	db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC2 CLEC11A ISM1 ADAMTS8	7.99e-05	192	53	4	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC2 CLEC11A ISM1 ADAMTS8	7.99e-05	192	53	4	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SH3TC2 VWF THSD7A MRC2	7.99e-05	192	53	4	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD163L1 ISM1 ADAMTS18 NOSTRIN	8.15e-05	193	53	4	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF THSD7A ADAMTS18 NOSTRIN	8.65e-05	196	53	4	5609b2d93172a488b35d854298a3a4e504e17e28
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF NOSTRIN ERVMER34-1 CA5A	8.83e-05	197	53	4	62c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell	distal-Endothelial-Bronchial_Vessel_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	0d1afd1ad7489c071db08b3dfff598423097d7e0
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF NOSTRIN ERVMER34-1 CA5A	8.83e-05	197	53	4	16f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCell	distal-Endothelial-Bronchial_Vessel_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	f45a93b5ad80a16b760acbaa6467648ffc05a0d3
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	VWF THSD7A ADAMTS18 NOSTRIN	8.83e-05	197	53	4	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF NOSTRIN ERVMER34-1 SLC3A2	9.00e-05	198	53	4	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	tumor_Lung-Endothelial_cells-Tumor_ECs\|tumor_Lung / Location, Cell class and cell subclass	VWF THSD7A ADAMTS18 NOSTRIN	9.00e-05	198	53	4	5228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCell	distal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VWF THSD7A ADAMTS18 NOSTRIN	9.00e-05	198	53	4	00fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF ISM1 NOSTRIN CA5A	9.18e-05	199	53	4	236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF ISM1 NOSTRIN CA5A	9.18e-05	199	53	4	c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCell	distal-3-mesenchymal-Myofibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 ADAMTS19 CLEC11A ISM1	9.18e-05	199	53	4	1f20addc0d138fec02ed6ca4c518169c568de263
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	VWF ITPRID2 NOSTRIN SLC3A2	9.18e-05	199	53	4	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPTBN5 VWF NOSTRIN CA5A	9.18e-05	199	53	4	d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAMTS19 MRC2 CLEC11A ADAMTS16	9.18e-05	199	53	4	8de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPTBN5 VWF NOSTRIN CA5A	9.18e-05	199	53	4	cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VWF THSD7A ADAMTS18 NOSTRIN	9.18e-05	199	53	4	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	wk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADAMTS19 MRC2 CLEC11A ADAMTS16	9.18e-05	199	53	4	ab0589c068c24aa989bdca083504fbad0c15221d
ToppCell	distal-mesenchymal-Myofibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 ADAMTS19 CLEC11A ISM1	9.36e-05	200	53	4	069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF ISM1 NOSTRIN CA5A	9.36e-05	200	53	4	c239e6f5d23caa9a59b83e9b352b2d6a691dcb28
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Endothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	VWF THSD7A ADAMTS18 NOSTRIN	9.36e-05	200	53	4	b65fb8d378abd91cdabf5faac5f4b90d527f8c44
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	MRC2 CLEC11A ADAMTS18 ADAMTS8	9.36e-05	200	53	4	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VWF THSD7A ADAMTS18 NOSTRIN	9.36e-05	200	53	4	2cb6e35add34b9dc564ebcf5d3cbc761325ca9f4
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF PCSK7 NOSTRIN SLC3A2	9.36e-05	200	53	4	50b8788494b744e0f0ec8c4d67a1c90ae09dca65
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF PCSK7 NOSTRIN SLC3A2	9.36e-05	200	53	4	f5f24273bee3259a4a3be99ba53b88defa1286c0
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF NOSTRIN ERVMER34-1 CA5A	9.36e-05	200	53	4	061ba851f941c616ddb462512e826c412881c3ce
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF THSD7A ADAMTS18 NOSTRIN	9.36e-05	200	53	4	310c75e13be9194312a8b686804edcf13d44caf5
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	VWF THSD7A ADAMTS18 NOSTRIN	9.36e-05	200	53	4	27507c4b41d45c7cc50e4993169c0302be22ee34
ToppCell	distal-mesenchymal-Myofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 ADAMTS19 CLEC11A ISM1	9.36e-05	200	53	4	61854a459385cd9295be37157a8f81a2c227dff3
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADAMTSL5 ADAMTS8 GPAT2	9.43e-05	74	53	3	c652ef04a1b8716b954ce913daa481cc02f4d44e
ToppCell	(05)_Ciliated-(1)_24hpi\|(05)_Ciliated / shred by cell type and Timepoint	CD163L1 DMBT1 NOSTRIN	1.58e-04	88	53	3	76959e7e3f6fae07c9881a29c28ba847be406694
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NKX6-3 ADAMTSL5 ADAMTS8	3.74e-04	118	53	3	d7dcffc0476a6e471debd83904a6569c6f27a594
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC2 RTP4 CA5A	4.43e-04	125	53	3	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	THSD7A ADAMTS18 RTP4	4.54e-04	126	53	3	28fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC2 RTP4 CA5A	4.54e-04	126	53	3	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_2\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	CD163L1 RP1L1 RTP4	4.64e-04	127	53	3	508b188ccbe5aa6ec0128c443aedb5a8ea35a6d0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GEMIN4 DMBT1 CA5A	5.43e-04	134	53	3	45c0cccca133ffc261ba45271d72b21f5402ec3c
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RP1L1 USH2A SSPOP	6.04e-04	139	53	3	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RP1L1 USH2A SSPOP	6.04e-04	139	53	3	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK\|Hippocampus / BrainAtlas - Mouse McCarroll V32	VWF NOSTRIN CA5A	6.04e-04	139	53	3	34398a6f21a1e670497655a7bb7f3cde9e117560
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TNFSF14 HAGHL UNC5D	6.04e-04	139	53	3	ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	VWF NOSTRIN CA5A	6.04e-04	139	53	3	450c4152c9fe4ec503271bb3cf93739918c59509
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 ADAMTS16 USH2A	6.16e-04	140	53	3	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTUD7A ADAMTS16 SSPOP	6.16e-04	140	53	3	7ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTUD7A ADAMTS16 SSPOP	6.16e-04	140	53	3	1a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCell	TCGA-Bile_Duct\|World / Sample_Type by Project: Shred V9	TNFSF14 C6 C8B	6.16e-04	140	53	3	ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PAPPA2 ADAMTSL5 ADAMTS8	6.29e-04	141	53	3	a32947b13e888850c979a54c137512e4b96d2f36
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PAPPA2 ADAMTSL5 ADAMTS8	6.29e-04	141	53	3	2cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTSL5 TCTN2 CA5A	6.42e-04	142	53	3	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	VWF NOSTRIN CA5A	6.56e-04	143	53	3	35d3652680c4dddd293301595d813161c66e5673
Disease	lifestyle measurement, alcohol consumption measurement	VWF RTP4 UNC5D	9.32e-04	115	49	3	EFO_0007878, EFO_0010724
Disease	Complement deficiency disease	C6 C8B	1.38e-03	33	49	2	C0272242
Disease	central corneal thickness	ADAMTS19 ADAMTS18 ADAMTS8 RTP4	1.72e-03	309	49	4	EFO_0005213
Disease	sexual dimorphism measurement	PAPPA2 SPTBN5 HAGHL DLGAP4 PCSK7 MAP3K11 NOSTRIN	2.21e-03	1106	49	7	EFO_0021796

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSCGTLNSTLWWERT	ABCA5	1621	Q8WWZ7
STWSSAGISWRSEAC	CAGE1	266	Q8TC20
WSECSSTCGAGWQRR	ADAMTS8	841	Q9UP79
RIGTGCSHTWDWRFS	ADORA2A-AS1	56	P86434
EWGTVCHDRWSTRNA	CD163L1	496	Q9NR16
RSRSNISGWWSSDDN	DLGAP4	196	Q9Y2H0
SRGSWFASPWSQCTA	ADAMTS16	1126	Q8TE57
NSRLQWVASSWSECS	ADAMTS18	1051	Q8TE60
AGEWSLWSPCSRTCS	ADAMTS19	636	Q8TE59
LWARSASTTPSCGWR	HAGHL	251	Q6PII5
TRQCSWFAGCTNRTW	ERVMER34-1	181	Q9H9K5
DWTFSTVRCWGERAR	PCSK7	571	Q16549
GWAGRAKLRSWCRAS	FAM218A	26	Q96MZ4
TLSWREAWASCEQQG	MRC2	256	Q9UBG0
EQAGRLNWWSTVCTS	OTUD7A	181	Q8TE49
AWAKCRSSWQASETE	ITPRID2	26	P28290
WVSWTRCSSSCGRGV	ADAMTSL5	51	Q6ZMM2
EEVGSCWNDSRWSLL	PRSS36	501	Q5K4E3
GWALCSANSELGWTR	PAPPA2	16	Q9BXP8
GRWCSQRSCAWQTSN	CA5A	31	P35218
SWLESCVAEQQGRWR	CNPPD1	186	Q9BV87
ENSSCTDKREWWTGR	ESPL1	1766	Q14674
NLGLSWRQEAARAWC	C5orf60	316	A6NFR6
WSSWSTCDATYKRSR	C6	571	P13671
SLWSRWGCSHRICSR	GPAT2	361	Q6NUI2
TGNRWCSWSLSQARL	SLC3A2	426	P08195
NTVACWEWSSGARTQ	FBXW2	206	Q9UKT8
SGTESTLWQCRNRGW	DMBT1	1956	Q9UGM3
WWQRSLSLARANSGD	ISM1	161	B1AKI9
WSNWSSCSGRRKTRQ	C8B	551	P07358
SNGERRACWAWGPSS	MAP3K11	556	Q16584
QNTRKSCVSSAWAWA	NOSTRIN	61	Q8IVI9
GWFRCSSCQRSWASA	RTP4	51	Q96DX8
NSAGKAPSSWTWCRT	USH2A	4716	O75445
QSWWDGSSQACRSCS	SSPOP	146	A2VEC9
WSNWSRCSKSCGSGV	THSD7A	1041	Q9UPZ6
ASAWKGSSRTVWCQR	THSD7A	1481	Q9UPZ6
TRTRNCWADTGQDWR	NKX6-3	106	A6NJ46
WHSRPSGCSSERARW	SH3TC2	1266	Q8TF17
NAEWSSARGSRLWCS	CYB5D2	176	Q8WUJ1
SWWRALGSTAAQSLS	SPTBN5	3631	Q9NRC6
SDDGSWWDHDCQRRL	CLEC11A	301	Q9Y240
WTTSQSCAAWQGCRR	CLUHP3	101	Q96NS8
AWCTDSGSDDSRRWS	WDFY3	3321	Q8IZQ1
WALSSGEQWCERASP	VWF	191	P04275
SRASSWGNCWQKDSE	RP1L1	2301	Q8IWN7
PCGRATSSSRVWWDS	TNFSF14	186	O43557
RLGRNSASWCVEWFN	TRIM25	541	Q14258
SAQRWAAVAGRWGCR	TMED7	6	Q9Y3B3
SSWTEWSACNVRCGR	UNC5D	256	Q6UXZ4
ISEAESLCQNWRGWR	ZSWIM8	31	A7E2V4
GAVNAVCWSQDRRWL	WDR27	556	A2RRH5
NCTSSWGRVWRATSS	USP40	956	Q9NVE5
VRWKRGLDWCSSNET	TCTN2	96	Q96GX1
WAFSDEWVACLGSNR	GEMIN4	431	P57678