Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	vasoactive intestinal polypeptide receptor activity	VIPR1 VIPR2 ADCYAP1R1	3.16e-07	3	137	3	GO:0004999
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11	6.74e-07	11	137	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11	2.01e-06	14	137	4	GO:0003964
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25	5.16e-06	37	137	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25	5.91e-06	38	137	5	GO:0070001
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ABCA13 ABCB5 ABCG1 ATP6V0A4 ATP1A4 ABCG5	1.02e-05	109	137	7	GO:0042626
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-11	1.16e-05	21	137	4	GO:0035613
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	2.11e-05	49	137	5	GO:0140359
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-11	1.17e-04	37	137	4	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11	1.31e-04	38	137	4	GO:0034061
GeneOntologyMolecularFunction	JUN kinase activity	MAPK8 MAPK10	1.40e-04	3	137	2	GO:0004705
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA1 ABCA13 ABCB5 ABCG1 ATP6V0A4 ATP1A4 ABCG5	2.31e-04	178	137	7	GO:0015399
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-11	2.77e-04	46	137	4	GO:0016893
GeneOntologyMolecularFunction	ATP-dependent activity	DDX19B ABCA1 MYO5A ABCA13 ABCB5 MFSD2A ABCG1 ATP6V0A4 MYH15 ATP1A4 DNAH5 DNAH8 ABCG5	3.16e-04	614	137	13	GO:0140657
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1D ABCA1 SLC35D2 NOX5 ABCA13 ABCB5 TRPC4 SLC22A15 TTYH2 CHRNG MFSD2A ABCG1 SLC12A3 ATP6V0A4 SLC39A6 ATP1A4 KCNT1 ABCG5 CACNA2D3	4.50e-04	1180	137	19	GO:0022857
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCA1 SLC35D2 ABCA13 ABCB5 MFSD2A ABCG1 SLC12A3 ATP6V0A4 SLC39A6 ATP1A4 ABCG5	4.57e-04	477	137	11	GO:0022804
GeneOntologyMolecularFunction	peptide hormone binding	VIPR1 VIPR2 ADCYAP1R1 SCTR	5.51e-04	55	137	4	GO:0017046
GeneOntologyMolecularFunction	cholesterol transfer activity	ABCA1 ABCG1 ABCG5	5.75e-04	24	137	3	GO:0120020
GeneOntologyMolecularFunction	sterol transfer activity	ABCA1 ABCG1 ABCG5	6.51e-04	25	137	3	GO:0120015
GeneOntologyMolecularFunction	alcohol binding	ABCA1 TRPC4 ABCG1 SCAP SNAP91	6.91e-04	102	137	5	GO:0043178
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DDX19B ABCA1 ABCA13 ABCB5 RHOG ABCG1 GNAO1 GNAT1 ATP1A4 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	8.99e-04	775	137	14	GO:0017111
GeneOntologyMolecularFunction	dynein light intermediate chain binding	CCDC88A DNAH5 DNAH8	9.13e-04	28	137	3	GO:0051959
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA1 MFSD2A ABCG1	9.13e-04	28	137	3	GO:0140326
GeneOntologyMolecularFunction	GPI-linked ephrin receptor activity	EPHA4 EPHA8	9.59e-04	7	137	2	GO:0005004
GeneOntologyMolecularFunction	thiamine pyrophosphate binding	HACL1 DHTKD1	1.27e-03	8	137	2	GO:0030976
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA1 ABCG1	1.27e-03	8	137	2	GO:0090554
GeneOntologyMolecularFunction	transporter activity	CACNA1D ABCA1 SLC35D2 NOX5 ABCA13 ABCB5 TRPC4 SLC22A15 TTYH2 CHRNG MFSD2A ABCG1 SLC12A3 ATP6V0A4 SLC39A6 ATP1A4 KCNT1 ABCG5 CACNA2D3	1.30e-03	1289	137	19	GO:0005215
GeneOntologyMolecularFunction	sterol binding	ABCA1 ABCG1 SCAP OSBPL11	1.44e-03	71	137	4	GO:0032934
GeneOntologyMolecularFunction	pyrophosphatase activity	DDX19B ABCA1 ABCA13 ABCB5 RHOG ABCG1 GNAO1 GNAT1 ATP1A4 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	1.90e-03	839	137	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DDX19B ABCA1 ABCA13 ABCB5 RHOG ABCG1 GNAO1 GNAT1 ATP1A4 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	1.92e-03	840	137	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DDX19B ABCA1 ABCA13 ABCB5 RHOG ABCG1 GNAO1 GNAT1 ATP1A4 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	1.92e-03	840	137	14	GO:0016818
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH5 DNAH8 HTT	2.07e-03	37	137	3	GO:0045505
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11	2.14e-03	79	137	4	GO:0004521
GeneOntologyMolecularFunction	dynactin binding	BBS4 HTT	2.95e-03	12	137	2	GO:0034452
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-11	1.20e-06	13	135	4	GO:0015074
Domain	ABC_tran	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	2.19e-05	48	132	5	PF00005
Domain	ABC_TRANSPORTER_2	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	2.19e-05	48	132	5	PS50893
Domain	ABC_TRANSPORTER_1	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	2.43e-05	49	132	5	PS00211
Domain	ABC_transporter-like	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	2.68e-05	50	132	5	IPR003439
Domain	HormR	VIPR1 VIPR2 ADCYAP1R1 SCTR	2.69e-05	25	132	4	SM00008
Domain	HRM	VIPR1 VIPR2 ADCYAP1R1 SCTR	4.28e-05	28	132	4	PF02793
Domain	Nucleoporin_Nup133/Nup155_C	NUP155 NUP133	4.96e-05	2	132	2	IPR007187
Domain	Nucleoporin_Nup133/Nup155_N	NUP155 NUP133	4.96e-05	2	132	2	IPR014908
Domain	GPCR_2_VIP_rcpt	VIPR1 VIPR2	4.96e-05	2	132	2	IPR001571
Domain	Nucleoporin_N	NUP155 NUP133	4.96e-05	2	132	2	PF08801
Domain	Nucleoporin_C	NUP155 NUP133	4.96e-05	2	132	2	PF03177
Domain	-	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	6.82e-05	248	132	9	1.25.40.20
Domain	AAA	ABCA1 ABCA13 ABCB5 ABCG1 DNAH5 DNAH8 ABCG5	7.39e-05	144	132	7	SM00382
Domain	AAA+_ATPase	ABCA1 ABCA13 ABCB5 ABCG1 DNAH5 DNAH8 ABCG5	7.39e-05	144	132	7	IPR003593
Domain	ANK	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	7.48e-05	251	132	9	SM00248
Domain	ANK_REPEAT	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	7.94e-05	253	132	9	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	8.19e-05	254	132	9	IPR020683
Domain	ANK_REP_REGION	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	8.19e-05	254	132	9	PS50297
Domain	GPCR_2_secretin-like_CS	VIPR1 VIPR2 ADCYAP1R1 SCTR	9.38e-05	34	132	4	IPR017983
Domain	Ankyrin_rpt	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	1.04e-04	262	132	9	IPR002110
Domain	Ank_2	ANKRD66 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	1.47e-04	215	132	8	PF12796
Domain	GPCR_2_VIP_rcpt_1	VIPR1 SCTR	1.48e-04	3	132	2	IPR001771
Domain	GPCR_2_extracellular_dom	VIPR1 VIPR2 ADCYAP1R1 SCTR	1.79e-04	40	132	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	VIPR1 VIPR2 ADCYAP1R1 SCTR	1.79e-04	40	132	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	VIPR1 VIPR2 ADCYAP1R1 SCTR	1.79e-04	40	132	4	PS50227
Domain	Ank	TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	2.19e-04	228	132	8	PF00023
Domain	P-loop_NTPase	DDX19B NLRP12 ABCA1 MYO5A ABCA13 ABCB5 RHOG ABCG1 MYH15 GNAO1 GNAT1 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	3.23e-04	848	132	16	IPR027417
Domain	7tm_2	VIPR1 VIPR2 ADCYAP1R1 SCTR	4.27e-04	50	132	4	PF00002
Domain	G_PROTEIN_RECEP_F2_2	VIPR1 VIPR2 ADCYAP1R1 SCTR	4.27e-04	50	132	4	PS00650
Domain	ABC2_membrane	ABCG1 ABCG5	4.89e-04	5	132	2	PF01061
Domain	ABC_2_trans	ABCG1 ABCG5	4.89e-04	5	132	2	IPR013525
Domain	MAPK_JNK	MAPK8 MAPK10	4.89e-04	5	132	2	IPR008351
Domain	-	DDX19B NLRP12 ABCA1 ABCA13 ABCB5 RHOG ABCG1 GNAO1 GNAT1 DNAH5 DNAH8 ABCG5 AGAP1 AGAP3	8.18e-04	746	132	14	3.40.50.300
Domain	GPCR_2_secretin-like	VIPR1 VIPR2 ADCYAP1R1 SCTR	8.56e-04	60	132	4	IPR000832
Domain	GPCR_2-like	VIPR1 VIPR2 ADCYAP1R1 SCTR	8.56e-04	60	132	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	VIPR1 VIPR2 ADCYAP1R1 SCTR	9.11e-04	61	132	4	PS50261
Domain	Gprotein_alpha_I	GNAO1 GNAT1	1.35e-03	8	132	2	IPR001408
Domain	DHC_N1	DNAH5 DNAH8	1.35e-03	8	132	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH8	1.35e-03	8	132	2	IPR013594
Domain	SET	SETD1B PRDM5 SETD3	3.02e-03	41	132	3	PF00856
Domain	ABC_A	ABCA1 ABCA13	3.12e-03	12	132	2	IPR026082
Domain	MAPK	MAPK8 MAPK10	3.12e-03	12	132	2	PS01351
Domain	MAP_kinase_CS	MAPK8 MAPK10	3.12e-03	12	132	2	IPR003527
Domain	ABC_transporter_CS	ABCA1 ABCB5 ABCG1	3.24e-03	42	132	3	IPR017871
Domain	MIRO-like	AGAP1 AGAP3	3.67e-03	13	132	2	IPR013684
Domain	Roc	AGAP1 AGAP3	3.67e-03	13	132	2	PF08477
Domain	THDP-binding	HACL1 DHTKD1	3.67e-03	13	132	2	IPR029061
Domain	-	HACL1 DHTKD1	3.67e-03	13	132	2	3.40.50.970
Domain	RECEPTOR_TYR_KIN_V_2	EPHA4 EPHA8	4.27e-03	14	132	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA4 EPHA8	4.27e-03	14	132	2	PS00790
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH8	4.27e-03	14	132	2	IPR024317
Domain	Tyr_kinase_rcpt_V_CS	EPHA4 EPHA8	4.27e-03	14	132	2	IPR001426
Domain	Dynein_HC_stalk	DNAH5 DNAH8	4.27e-03	14	132	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH8	4.27e-03	14	132	2	IPR013602
Domain	DHC_N2	DNAH5 DNAH8	4.27e-03	14	132	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH5 DNAH8	4.27e-03	14	132	2	IPR011704
Domain	EphA2_TM	EPHA4 EPHA8	4.27e-03	14	132	2	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHA4 EPHA8	4.27e-03	14	132	2	IPR001090
Domain	Eph_TM	EPHA4 EPHA8	4.27e-03	14	132	2	IPR027936
Domain	EPH_lbd	EPHA4 EPHA8	4.27e-03	14	132	2	SM00615
Domain	Ephrin_lbd	EPHA4 EPHA8	4.27e-03	14	132	2	PF01404
Domain	MT	DNAH5 DNAH8	4.27e-03	14	132	2	PF12777
Domain	AAA_8	DNAH5 DNAH8	4.27e-03	14	132	2	PF12780
Domain	Tyr_kinase_ephrin_rcpt	EPHA4 EPHA8	4.27e-03	14	132	2	IPR016257
Domain	EPH_LBD	EPHA4 EPHA8	4.27e-03	14	132	2	PS51550
Domain	AAA_5	DNAH5 DNAH8	4.27e-03	14	132	2	PF07728
Domain	DHC_fam	DNAH5 DNAH8	4.90e-03	15	132	2	IPR026983
Domain	Dynein_heavy	DNAH5 DNAH8	4.90e-03	15	132	2	PF03028
Domain	Dynein_heavy_dom	DNAH5 DNAH8	4.90e-03	15	132	2	IPR004273
Domain	SET_dom	SETD1B PRDM5 SETD3	5.31e-03	50	132	3	IPR001214
Domain	SET	SETD1B PRDM5 SETD3	5.31e-03	50	132	3	PS50280
Domain	GproteinA_insert	GNAO1 GNAT1	5.58e-03	16	132	2	IPR011025
Domain	-	GNAO1 GNAT1	5.58e-03	16	132	2	1.10.400.10
Domain	G-alpha	GNAO1 GNAT1	5.58e-03	16	132	2	PF00503
Domain	G_alpha	GNAO1 GNAT1	5.58e-03	16	132	2	SM00275
Domain	Gprotein_alpha_su	GNAO1 GNAT1	6.29e-03	17	132	2	IPR001019
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10 HTT	7.68e-06	6	104	3	M47680
Pathway	KEGG_ABC_TRANSPORTERS	ABCA1 ABCA13 ABCB5 ABCG1 ABCG5	1.71e-05	44	104	5	M11911
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	VIPR1 VIPR2 ADCYAP1R1 SCTR	2.65e-05	24	104	4	MM15992
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	VIPR1 VIPR2 ADCYAP1R1 SCTR	2.65e-05	24	104	4	M39643
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	VIPR1 VIPR2 ADCYAP1R1 SCTR	9.70e-05	33	104	4	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	VIPR1 VIPR2 ADCYAP1R1 SCTR	9.70e-05	33	104	4	M10322
Pubmed	PAC1, VPAC1, and VPAC2 Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies.	VIPR1 VIPR2 ADCYAP1R1	6.38e-08	3	140	3	36430275
Pubmed	Vasoactive intestinal peptide (VIP) receptor expression in monocyte-derived macrophages from COPD patients.	VIPR1 VIPR2 ADCYAP1R1	6.38e-08	3	140	3	20026142
Pubmed	Association of selected ABC gene family single nucleotide polymorphisms with postprandial lipoproteins: results from the population-based Hortega study.	ABCA1 ABCG1 ABCG5	2.55e-07	4	140	3	20170916
Pubmed	Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.	ABCA1 ABCG1 ABCG5	2.55e-07	4	140	3	12777468
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	2.55e-07	4	140	3	10469592
Pubmed	IL-6 and PACAP receptor expression and localization after global brain ischemia in mice.	VIPR1 VIPR2 ADCYAP1R1	2.55e-07	4	140	3	22669509
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	6.35e-07	5	140	3	12629516
Pubmed	Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation.	VIPR1 VIPR2 ADCYAP1R1	6.35e-07	5	140	3	12417650
Pubmed	PACAP/VIP and receptor characterization in micturition pathways in mice with overexpression of NGF in urothelium.	VIPR1 VIPR2 ADCYAP1R1	6.35e-07	5	140	3	20449688
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-25 ERVK-11	7.37e-07	18	140	4	18664271
Pubmed	PACAP/PAC1 autocrine system promotes proliferation and astrogenesis in neural progenitor cells.	VIPR1 VIPR2 ADCYAP1R1	1.27e-06	6	140	3	17115416
Pubmed	Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium.	VIPR1 VIPR2 ADCYAP1R1	1.27e-06	6	140	3	22700375
Pubmed	Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.	ABCA1 ABCG1 SCAP	1.27e-06	6	140	3	32514064
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT140 SZT2 VPS50 CCDC88A NUP155 WASHC5 SUPT6H MIB1 MED23 ESPL1 KCNT1 AGAP1	1.70e-06	529	140	12	14621295
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25 ERVK-11	2.33e-06	94	140	6	21542922
Pubmed	Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice.	ABCA1 TNFSF4 ABCG5	5.27e-06	9	140	3	14701919
Pubmed	JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway.	MAPK8 MAPK10 EPHA4	5.27e-06	9	140	3	10523642
Pubmed	Expanding the substantial interactome of NEMO using protein microarrays.	DDX19B FLT3 TTYH2 SRPK1 TSLP EPHA4	5.50e-06	109	140	6	20098747
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DDX19B SZT2 PIGK DHRS7B EXOC5 NUP155 AGL RRP12 NUP133 ANKRD28 TTI1 ANKRD52	6.77e-06	606	140	12	36538041
Pubmed	Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors.	VIPR1 ADCYAP1R1 SCTR	7.50e-06	10	140	3	15670850
Pubmed	Altered expression of vasoactive intestinal peptide receptors in T lymphocytes and aberrant Th1 immunity in multiple sclerosis.	VIPR1 VIPR2	1.61e-05	2	140	2	17077178
Pubmed	Recent advances in the regulation of ABCA1 and ABCG1 by lncRNAs.	ABCA1 ABCG1	1.61e-05	2	140	2	33545111
Pubmed	Selective gene expression and activation-dependent regulation of vasoactive intestinal peptide receptor type 1 and type 2 in human T cells.	VIPR1 VIPR2	1.61e-05	2	140	2	11160313
Pubmed	VIP/PACAP receptor mediation of cutaneous active vasodilation during heat stress in humans.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	20395540
Pubmed	ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease.	ABCA1 ABCG1	1.61e-05	2	140	2	31167810
Pubmed	Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.	ABCA1 ABCG1	1.61e-05	2	140	2	22315310
Pubmed	Tissue specific expression of different human receptor types for pituitary adenylate cyclase activating polypeptide and vasoactive intestinal polypeptide: implications for their role in human physiology.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	8933357
Pubmed	[Regulation of ABCA1 and ABCG1 gene expression in the intraabdominal adipose tissue].	ABCA1 ABCG1	1.61e-05	2	140	2	27420620
Pubmed	ABCA1 and ABCG1 DNA methylation in epicardial adipose tissue of patients with coronary artery disease.	ABCA1 ABCG1	1.61e-05	2	140	2	34837967
Pubmed	Genetic variations in ABCA1/G1 associated with plasma lipid levels and risk of ischemic stroke.	ABCA1 ABCG1	1.61e-05	2	140	2	35219812
Pubmed	Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus.	ABCA1 ABCG1	1.61e-05	2	140	2	18490524
Pubmed	Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid.	ABCA1 ABCG1	1.61e-05	2	140	2	24462739
Pubmed	Distribution of mRNA for VIP and PACAP receptors in human cerebral arteries and cranial ganglia.	VIPR1 ADCYAP1R1	1.61e-05	2	140	2	11930171
Pubmed	Nitric oxide and receptors for VIP and PACAP in cutaneous active vasodilation during heat stress in humans.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	22961270
Pubmed	Impact of Perturbed Pancreatic β-Cell Cholesterol Homeostasis on Adipose Tissue and Skeletal Muscle Metabolism.	ABCA1 ABCG1	1.61e-05	2	140	2	27702832
Pubmed	Alterations of vasoactive intestinal polypeptide receptors in allergic rhinitis.	VIPR1 VIPR2	1.61e-05	2	140	2	21711977
Pubmed	Combined inhibition of Notch and FLT3 produces synergistic cytotoxic effects in FLT3/ITD+ acute myeloid leukemia.	CXCR3 FLT3	1.61e-05	2	140	2	32296014
Pubmed	Expression of pituitary adenylate cyclase-activating polypeptide 1 and 2 receptor mRNA in gallbladder tissue of patients with gallstone or gallbladder polyps.	VIPR1 VIPR2	1.61e-05	2	140	2	16552823
Pubmed	Radical reversal of vasoactive intestinal peptide (VIP) receptors during early lymphopoiesis.	VIPR1 VIPR2	1.61e-05	2	140	2	21878358
Pubmed	Placental ABCA1 and ABCG1 expression in gestational disease: Pre-eclampsia affects ABCA1 levels in syncytiotrophoblasts.	ABCA1 ABCG1	1.61e-05	2	140	2	23880356
Pubmed	Gene expression of vasoactive intestinal peptide receptors in human lung cancer.	VIPR1 VIPR2	1.61e-05	2	140	2	21769421
Pubmed	Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection.	CSF2RB TSLP	1.61e-05	2	140	2	23024277
Pubmed	Uraemic plasma decreases the expression of ABCA1, ABCG1 and cell-cycle genes in human coronary arterial endothelial cells.	ABCA1 ABCG1	1.61e-05	2	140	2	17082211
Pubmed	Identification and characterization of five-transmembrane isoforms of human vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors.	VIPR1 VIPR2	1.61e-05	2	140	2	16934434
Pubmed	Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.	ABCA1 ABCG1	1.61e-05	2	140	2	16730733
Pubmed	Immunohistochemical localization and distribution of VIP/PACAP receptors in human lung.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	10764955
Pubmed	p62/mTOR/LXRα pathway inhibits cholesterol efflux mediated by ABCA1 and ABCG1 during autophagy blockage.	ABCA1 ABCG1	1.61e-05	2	140	2	31101336
Pubmed	Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.	ABCA1 ABCG1	1.61e-05	2	140	2	30864945
Pubmed	Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.	ABCA1 ABCG1	1.61e-05	2	140	2	19839639
Pubmed	Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients.	VIPR1 VIPR2	1.61e-05	2	140	2	31089161
Pubmed	PRDM5 promotes the proliferation and invasion of murine melanoma cells through up-regulating JNK expression.	PRDM5 MAPK8	1.61e-05	2	140	2	27485778
Pubmed	Associations of ATP-binding cassette transporter A1 and G1 with insulin secretion in human insulinomas.	ABCA1 ABCG1	1.61e-05	2	140	2	22466164
Pubmed	Effect of positive charge in VIP 16gamma-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function.	VIPR1 VIPR2	1.61e-05	2	140	2	17883247
Pubmed	The neurotransmitter VIP expands the pool of symmetrically dividing postnatal dentate gyrus precursors via VPAC2 receptors or directs them toward a neuronal fate via VPAC1 receptors.	VIPR1 VIPR2	1.61e-05	2	140	2	19650041
Pubmed	Localization and characterization of pituitary adenylate cyclase-activating polypeptide receptors in the human cerebellum during development.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	16572459
Pubmed	Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation.	ABCA1 ABCG1	1.61e-05	2	140	2	17121837
Pubmed	Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go.	GNAO1 GNAT1	1.61e-05	2	140	2	1697681
Pubmed	Lipid efflux by the ATP-binding cassette transporters ABCA1 and ABCG1.	ABCA1 ABCG1	1.61e-05	2	140	2	16798073
Pubmed	Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway.	ABCA1 ABCG1	1.61e-05	2	140	2	12032171
Pubmed	Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells.	ABCA1 ABCG1	1.61e-05	2	140	2	21111593
Pubmed	In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.	TNFSF4 TSLP	1.61e-05	2	140	2	18060034
Pubmed	Expression of pituitary adenylate cyclase activating polypeptide receptors in the early mouse embryo as assessed by reverse transcription polymerase chain reaction and in situ hybridisation.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	8892388
Pubmed	Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.	ABCA1 ABCG1	1.61e-05	2	140	2	16702602
Pubmed	Imidazoquinoline acts as immune adjuvant for functional alteration of thymic stromal lymphopoietin-mediated allergic T cell response.	TNFSF4 TSLP	1.61e-05	2	140	2	18832690
Pubmed	Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.	ABCA1 ABCG1	1.61e-05	2	140	2	17967783
Pubmed	High glucose, unsaturated and saturated fatty acids differentially regulate expression of ATP-binding cassette transporters ABCA1 and ABCG1 in human macrophages.	ABCA1 ABCG1	1.61e-05	2	140	2	19287193
Pubmed	Differential expression of vasoactive intestinal peptide receptors 1 and 2 (VIP-R1 and VIP-R2) mRNA in murine lymphocytes.	VIPR1 VIPR2	1.61e-05	2	140	2	8784257
Pubmed	ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase.	ABCA1 ABCG1	1.61e-05	2	140	2	20798376
Pubmed	Neuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms.	MAPK8 MAPK10	1.61e-05	2	140	2	28664455
Pubmed	Proteasomal inhibition promotes ATP-binding cassette transporter A1 (ABCA1) and ABCG1 expression and cholesterol efflux from macrophages in vitro and in vivo.	ABCA1 ABCG1	1.61e-05	2	140	2	21817095
Pubmed	Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.	ABCA1 ABCG1	1.61e-05	2	140	2	19168441
Pubmed	Differential regulation of ABCA1 and ABCG1 gene expressions in the remodeling mouse hippocampus after entorhinal cortex lesion and liver-X receptor agonist treatment.	ABCA1 ABCG1	1.61e-05	2	140	2	24661912
Pubmed	c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.	MAPK8 MAPK10	1.61e-05	2	140	2	21824499
Pubmed	The influence of house dust mite sublingual immunotherapy on the TSLP-OX40L signaling pathway in patients with allergic rhinitis.	TNFSF4 TSLP	1.61e-05	2	140	2	27012942
Pubmed	ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.	ABCA1 ABCG1	1.61e-05	2	140	2	23139370
Pubmed	The implication of adipocyte ATP-binding cassette A1 and G1 transporters in metabolic complications of obesity.	ABCA1 ABCG1	1.61e-05	2	140	2	31172973
Pubmed	VIP impairs acquisition of the macrophage proinflammatory polarization profile.	VIPR1 VIPR2	1.61e-05	2	140	2	27381006
Pubmed	Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.	ABCA1 ABCG1	1.61e-05	2	140	2	29946056
Pubmed	Impaired cardiorespiratory responses to hypercapnia in neonatal mice lacking PAC1 but not VPAC2 receptors.	VIPR2 ADCYAP1R1	1.61e-05	2	140	2	33146556
Pubmed	Expression of vasoactive intestinal peptide (VIP) receptors in human uterus.	VIPR1 VIPR2	1.61e-05	2	140	2	11072126
Pubmed	Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages.	ABCA1 ABCG1	1.61e-05	2	140	2	22209005
Pubmed	Effect of insulin insufficiency on ultrastructure and function in skeletal muscle.	ABCA1 ABCG1	1.61e-05	2	140	2	38124345
Pubmed	[Role of the ABC transporters A1 and G1, key reverse cholesterol transport proteins, in atherosclerosis].	ABCA1 ABCG1	1.61e-05	2	140	2	27239842
Pubmed	HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.	ABCA1 ABCG1	1.61e-05	2	140	2	23319699
Pubmed	Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation.	TNFSF4 TSLP	1.61e-05	2	140	2	17666213
Pubmed	VPAC1 and VPAC2 receptor deficiencies negatively influence pregnancy outcome through distinct and overlapping modulations of immune, trophoblast and vascular functions.	VIPR1 VIPR2	1.61e-05	2	140	2	36328148
Pubmed	Expression of ABC transporters during syncytialization in preeclampsia.	ABCA1 ABCG1	1.61e-05	2	140	2	35124425
Pubmed	Angiotensin-(1-7) upregulates expression of adenosine triphosphate-binding cassette transporter A1 and adenosine triphosphate-binding cassette transporter G1 through the Mas receptor through the liver X receptor alpha signalling pathway in THP-1 macrophages treated with angiotensin-II.	ABCA1 ABCG1	1.61e-05	2	140	2	25225013
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.61e-05	2	140	2	11672541
Pubmed	Cellular cholesterol regulates ubiquitination and degradation of the cholesterol export proteins ABCA1 and ABCG1.	ABCA1 ABCG1	1.61e-05	2	140	2	24500716
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	VIPR1 VIPR2 CXCR3 ADCYAP1R1 SCTR GNAO1 GNAT1	1.76e-05	200	140	7	18240029
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	SCAP WASHC5 SUPT6H ESPL1	2.27e-05	41	140	4	8724849
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYO5A SIPA1L3 NAA50 PPP1R13L CCDC88A NUP155 WASHC5 RRP12 MIB1 NUP133 SLC39A6 ANKRD28 TTI1 MAPK8 ANKRD52	2.30e-05	1049	140	15	27880917
Pubmed	High-density lipoprotein-mediated transcellular cholesterol transport in mouse aortic endothelial cells.	ABCA1 ABCG1	4.81e-05	3	140	2	26255968
Pubmed	JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy.	MAPK8 MAPK10	4.81e-05	3	140	2	30685843
Pubmed	Homocysteine accelerates atherosclerosis via inhibiting LXRα-mediated ABCA1/ABCG1-dependent cholesterol efflux from macrophages.	ABCA1 ABCG1	4.81e-05	3	140	2	30393020
Pubmed	JNK1 is required to preserve cardiac function in the early response to pressure overload.	MAPK8 MAPK10	4.81e-05	3	140	2	16579967
Pubmed	Cellular physiology of cholesterol efflux in vascular endothelial cells.	ABCA1 ABCG1	4.81e-05	3	140	2	15492319
Pubmed	Specific pathophysiological functions of JNK isoforms in the brain.	MAPK8 MAPK10	4.81e-05	3	140	2	15673436
Pubmed	HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.	ABCA1 HTT	4.81e-05	3	140	2	16192271
Interaction	GPR182 interactions	DDX19B VPS50 INTS8 DHRS7B CDC45 EXOC5 THADA LPCAT2 WASHC5 SLC39A6 ANKRD28 TTI1 MED23 HTT	2.12e-06	455	134	14	int:GPR182
GeneFamily	Vasoactive intestinal peptide receptor family	VIPR1 VIPR2 ADCYAP1R1	1.41e-07	3	95	3	264
GeneFamily	Ankyrin repeat domain containing	ANKRD66 TRPC4 ANKRD30B PPP1R13L MIB1 ANKRD28 ANKRD52 AGAP1 AGAP3	5.13e-06	242	95	9	403
GeneFamily	Blood group antigens\|CD molecules\|ATP binding cassette subfamily G	ABCG1 ABCG5	2.70e-04	5	95	2	811
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD28 ANKRD52	4.04e-04	6	95	2	699
GeneFamily	Nucleoporins	DDX19B NUP155 NUP133	6.24e-04	32	95	3	1051
GeneFamily	Mitogen-activated protein kinases	MAPK8 MAPK10	2.05e-03	13	95	2	651
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA4 EPHA8	2.39e-03	14	95	2	1095
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA13	2.39e-03	14	95	2	805
GeneFamily	Dyneins, axonemal	DNAH5 DNAH8	3.53e-03	17	95	2	536
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP3	3.53e-03	17	95	2	1291
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VIPR2 FLT3 TTYH2 ANTXR2 SLC12A3 CSF2RB GNAO1	6.16e-07	162	134	7	86a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB ESPL1 FMNL1	7.87e-07	168	134	7	c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCell	Immune-dendritic_cell\|World / Lineage, Cell type, age group and donor	FLT3 TTYH2 CCDC88A ANTXR2 SLC12A3 CSF2RB GNAO1	8.86e-07	171	134	7	6a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell	Children_(3_yrs)-Immune-dendritic_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT3 TTYH2 CCDC88A ANTXR2 SLC12A3 CSF2RB GNAO1	8.86e-07	171	134	7	6a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	OLR1 ABCG1 CCDC88A LPCAT2 RASGEF1B OSBPL11 MOB3B	1.30e-06	181	134	7	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5A NAA50 OLR1 DHRS7B ABCG1 CCDC88A CSF2RB	1.55e-06	186	134	7	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	CXCR3 FLT3 TTYH2 CCDC88A SCAP ANTXR2 CSF2RB	1.61e-06	187	134	7	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.67e-06	188	134	7	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1D SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.67e-06	188	134	7	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.67e-06	188	134	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OLR1 ABCG1 CCDC88A RASGEF1B OSBPL11 MOB3B ANKRD28	1.67e-06	188	134	7	d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.73e-06	189	134	7	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	SFTPB SIPA1L3 SLC22A15 OLR1 MFSD2A DNAH5 CACNA2D3	1.73e-06	189	134	7	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TTYH2 TNFSF4 ANTXR2 SLC12A3 CSF2RB ATP1A4	1.79e-06	190	134	7	2ff4b50b864a35f22c558d7d585cd2b54612b50c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TTYH2 TNFSF4 ANTXR2 SLC12A3 CSF2RB ATP1A4	1.79e-06	190	134	7	5175bf022d55a52988014abe7cece326a8406a38
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TTYH2 TNFSF4 ANTXR2 SLC12A3 CSF2RB ATP1A4	1.79e-06	190	134	7	29e60b9b1c86b44550619c01306b8b1bb2e340dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.79e-06	190	134	7	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	MYO5A OLR1 ABCG1 CCDC88A LPCAT2 RASGEF1B MOB3B	1.85e-06	191	134	7	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FLT3 ABCA1 TRPC4 SLIT2 ANTXR2 ITM2A	2.29e-06	126	134	6	3a14d4eb8803827946c36faeeb7ae2913418d421
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	ABCA1 MYO5A OLR1 ABCG1 CCDC88A RASGEF1B MOB3B	2.35e-06	198	134	7	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO5A SLC22A15 OLR1 ABCG1 CCDC88A MOB3B FMNL1	2.43e-06	199	134	7	22001aa733273e784051b7f750e07d99aaf7a225
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_E\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	TRPC4 SEMA4G AGL MAPK10 ITM2A ABCG5	3.42e-06	135	134	6	35928195cf34f055b353562c96f451aef2344d64
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-tDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CACNA1D CXCR3 FLT3 SZT2 HSPA12B SLC12A3	5.16e-06	145	134	6	a6c291811bf62f1c13f1b4b396d75c2223cf1c7d
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT3 SIPA1L3 SLC12A3 GNAO1 DHTKD1 FMNL1	7.57e-06	155	134	6	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	368C-Myeloid-Dendritic-cDC1\|368C / Donor, Lineage, Cell class and subclass (all cells)	CXCR3 FLT3 TTYH2 PADI6 GNAO1 DHTKD1	8.45e-06	158	134	6	c276a259e20ee704e2d04baf693e8d677f96f654
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAA50 OLR1 ABCG1 CCDC88A CSF2RB RRP12	8.45e-06	158	134	6	f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT3 TTYH2 TNFSF4 ANTXR2 CSF2RB GNAO1	9.41e-06	161	134	6	cd41abb7ae659d3d314281783a0aaad562b26037
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|343B / Donor, Lineage, Cell class and subclass (all cells)	NLRP12 OLR1 ABCG1 CCDC88A RASGEF1B MOB3B	9.75e-06	162	134	6	0acb8f7b51bf422d4f4f8e99bd10360163ae4eb7
ToppCell	COVID-mono3\|COVID / Condition, Cell_class and T cell subcluster	ABCA1 TBC1D30 OLR1 MFSD2A MOB3B MAPK10	1.01e-05	163	134	6	6ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX19B ZKSCAN5 SEMA4G RRP12 FMNL1 TBCE	1.01e-05	163	134	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	COVID-mono3-\|COVID / Condition, Cell_class and T cell subcluster	ABCA1 TBC1D30 OLR1 MFSD2A MOB3B MAPK10	1.01e-05	163	134	6	26661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FLT3 SIPA1L3 SEMA4G FMNL1 CACNA2D3 EPHA8	1.16e-05	167	134	6	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	FLT3 SIPA1L3 SEMA4G FMNL1 CACNA2D3 EPHA8	1.16e-05	167	134	6	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	OLR1 CCDC88A CSF2RB RASGEF1B MOB3B GNAO1	1.42e-05	173	134	6	a112da5b0ab6e1f13d1a7dfa72c67c9a95fa9243
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCR3 FLT3 CSF2RB MYH15 FMNL1 CACNA2D3	1.46e-05	174	134	6	4120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TNFSF4 SLC12A3 CSF2RB GNAO1 FMNL1	1.51e-05	175	134	6	393da565f61ba640410419a0cabaaf5c1056580a
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TNFSF4 SLC12A3 CSF2RB GNAO1 FMNL1	1.51e-05	175	134	6	271b56d4ab940959d28ca4b86ce2750350dfc717
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT3 TNFSF4 SLC12A3 CSF2RB GNAO1 FMNL1	1.51e-05	175	134	6	5168340c6045bbc7d67276afb719b051d1cb65a2
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB SNAP91	1.61e-05	177	134	6	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB SNAP91	1.61e-05	177	134	6	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SZT2 SIPA1L3 BBS4 CCDC88A TTI1 FMNL1	1.66e-05	178	134	6	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXCR3 FLT3 TTYH2 SLC12A3 CSF2RB SLC39A6	1.72e-05	179	134	6	bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	1.77e-05	180	134	6	350ba05cec45a788ab33530cc1346daddb00f884
ToppCell	droplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 OLR1 DHRS7B ABCG1 CSF2RB LONRF3	1.83e-05	181	134	6	8fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC22A15 OLR1 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	1.89e-05	182	134	6	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	1.89e-05	182	134	6	0beffe6b9b36cfd196ec98a18f6ded080c162f90
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 TRPC4 SLIT2 ANTXR2 GNAO1 CNTN1	1.89e-05	182	134	6	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH2 OLR1 DHRS7B ABCG1 CSF2RB LONRF3	1.89e-05	182	134	6	be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VIPR2 TRPC4 SLIT2 ANTXR2 GNAO1 CNTN1	1.89e-05	182	134	6	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	COVID-19-APC-like-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	FLT3 TTYH2 CCDC88A SLC12A3 GNAO1 FMNL1	1.95e-05	183	134	6	703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	FLT3 TTYH2 CCDC88A SLC12A3 GNAO1 FMNL1	1.95e-05	183	134	6	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCell	Control-APC-like\|Control / group, cell type (main and fine annotations)	FLT3 TTYH2 CCDC88A SLC12A3 GNAO1 FMNL1	1.95e-05	183	134	6	c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCell	cellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLT3 TTYH2 TNFSF4 ANTXR2 SLC12A3 ATP1A4	1.95e-05	183	134	6	e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCell	CTRL-Myeloid-cDC\|CTRL / Disease state, Lineage and Cell class	FLT3 TTYH2 TNFSF4 ANTXR2 GNAO1 CACNA2D3	1.95e-05	183	134	6	20c4d16de7e090df3556a4458f783383a26871b6
ToppCell	COVID-19-APC-like\|COVID-19 / group, cell type (main and fine annotations)	FLT3 TTYH2 CCDC88A SLC12A3 GNAO1 FMNL1	1.95e-05	183	134	6	b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ABCA13 MYH15 ATP1A4 DNAH5 CNTN1	2.01e-05	184	134	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5A NAA50 OLR1 DHRS7B ABCG1 CSF2RB	2.01e-05	184	134	6	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ABCA13 MYH15 ATP1A4 DNAH5 CNTN1	2.01e-05	184	134	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ABCA13 MYH15 ATP1A4 DNAH5 CNTN1	2.01e-05	184	134	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	CXCR3 FLT3 CCDC88A SLC12A3 CSF2RB DHTKD1	2.01e-05	184	134	6	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 TTYH2 OLR1 ABCG1 LONRF3 AGAP1	2.07e-05	185	134	6	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC2\|Liver / Manually curated celltypes from each tissue	FLT3 TTYH2 CCDC88A SLC12A3 LPCAT2 CACNA2D3	2.13e-05	186	134	6	92ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	MYO5A OLR1 ABCG1 CCDC88A CSF2RB AGAP1	2.13e-05	186	134	6	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTPB ABCA13 SRPK1 MFSD2A SCTR ANKRD28	2.13e-05	186	134	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	CACNA1D SFTPB ABCA13 MFSD2A SCTR DNAH5	2.26e-05	188	134	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 OLR1 DHRS7B ABCG1 LONRF3 AGAP1	2.33e-05	189	134	6	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	2.33e-05	189	134	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	2.33e-05	189	134	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 OLR1 DHRS7B ABCG1 LONRF3 AGAP1	2.33e-05	189	134	6	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	(3)_DC_activated\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FLT3 TTYH2 TNFSF4 SLC12A3 CSF2RB GNAO1	2.33e-05	189	134	6	e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	2.33e-05	189	134	6	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D SLC22A15 SLC12A3 TMEM72 ATP6V0A4 CACNA2D3	2.40e-05	190	134	6	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VIPR2 NBPF19 SLIT2 ANTXR2 ITM2A EPHA4	2.40e-05	190	134	6	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	2.47e-05	191	134	6	d45b6aa64667d29ac043c3987902e7f7ddbcf940
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	MYO5A SLC22A15 OLR1 ABCG1 CCDC88A MOB3B	2.47e-05	191	134	6	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	Mild-Myeloid-mDC\|Mild / Condition, Lineage, Cell class and cell subclass	FLT3 TTYH2 TNFSF4 ANTXR2 ATP1A4 CACNA2D3	2.55e-05	192	134	6	da3952bd5c96242c15eb76678d0608ae2926a16e
ToppCell	Mild-Myeloid-mDC-\|Mild / Condition, Lineage, Cell class and cell subclass	FLT3 TTYH2 TNFSF4 ANTXR2 ATP1A4 CACNA2D3	2.55e-05	192	134	6	8520b3fdf4508ac66f7918da613abc928ab5832a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	2.55e-05	192	134	6	49a34b55788d7ca955936fff1c0501ed674a9f3c
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 TTYH2 ANTXR2 SLC12A3 GNAO1 ATP1A4	2.62e-05	193	134	6	7426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 TTYH2 ANTXR2 SLC12A3 GNAO1 ATP1A4	2.62e-05	193	134	6	a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	2.62e-05	193	134	6	e1eee31db283aa49568b50f2ddd99f0054c99fbe
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD13 TTYH2 RHOG ABCG1 NKAIN1 GNAO1	2.70e-05	194	134	6	61b59f8e2c68851d827b058cf03904f8125e8047
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB DHTKD1	2.70e-05	194	134	6	bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OLR1 ABCG1 CCDC88A RASGEF1B OSBPL11 MOB3B	2.70e-05	194	134	6	69cf7c989ac355c459db13f9d4267b55adc3c174
ToppCell	cellseq-Immune-Immune_Myeloid-Myeloid_Dendritic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CXCR3 FLT3 SLC12A3 GNAO1 FMNL1 CACNA2D3	2.70e-05	194	134	6	74d588de2f84a4ef112fd642f7e112a542d5ef11
ToppCell	medial-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB DHTKD1	2.70e-05	194	134	6	d58be6454a0795d6771036a1620553a153861615
ToppCell	10x5'-Liver-Myeloid_Dendritic\|Liver / Manually curated celltypes from each tissue	FLT3 TTYH2 CCDC88A SLC12A3 MYH15 CACNA2D3	2.70e-05	194	134	6	e6391bc7073831847c469ef0b0c437118e1f151f
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB DHTKD1	2.70e-05	194	134	6	0117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	FLT3 TTYH2 CCDC88A CSF2RB LPCAT2 CACNA2D3	2.70e-05	194	134	6	e2d9186a7e8d1a4a71d7bd6dba7fc955d55479e6
ToppCell	ASK440-Endothelial-Endothelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	VIPR1 FAT4 HSPA12B F8 ITM2A EPHA4	2.78e-05	195	134	6	304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell	Immune-alveolar_macrophage_(MARCO_positive)\|World / Lineage, Cell type, age group and donor	SLC22A15 OLR1 ABCG1 CCDC88A OSBPL11 MOB3B	2.78e-05	195	134	6	f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	ABCA1 MYO5A OLR1 CCDC88A MOB3B FMNL1	2.78e-05	195	134	6	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	Control-Myeloid\|Control / Disease state, Lineage and Cell class	ABCA1 OLR1 ABCG1 CCDC88A RASGEF1B MOB3B	2.78e-05	195	134	6	46ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VIPR2 NBPF19 SLIT2 ANTXR2 ITM2A EPHA4	2.78e-05	195	134	6	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	distal-Hematologic-Plasmacytoid_Dendritic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VIPR2 CXCR3 FLT3 SLC12A3 CSF2RB MYH15	2.86e-05	196	134	6	170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCell	ILEUM-inflamed-(3)_DC2\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLT3 OLR1 CCDC88A LPCAT2 GNAO1 CACNA2D3	2.86e-05	196	134	6	0a7f77ed4ea3afdd9ad8a2d2c5df83778be5197b
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OLR1 ABCG1 CCDC88A LPCAT2 RASGEF1B MOB3B	2.86e-05	196	134	6	5fe6534af65d43eeacd4b031310242b4f706008b
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	FLT3 MYO5A CCDC88A RASGEF1B MOB3B FMNL1	2.94e-05	197	134	6	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLT3 TTYH2 CHRNG CDC45 MYH15 GNAO1	2.94e-05	197	134	6	81dd7f9318f0ba175352e5156c24772427e0b34f
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	MYO5A OLR1 ABCG1 CCDC88A MOB3B FMNL1	3.03e-05	198	134	6	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
Drug	AC1L4RIC	VIPR1 VIPR2 ADCYAP1R1 SCTR	5.88e-09	5	135	4	CID000162562
Disease	tubulin-specific chaperone E measurement	NLRP12 TBCE	5.67e-05	3	129	2	EFO_0802167
Disease	uric acid measurement	FAT4 ABCA1 PCNX3 SIPA1L3 ZKSCAN5 ADCYAP1R1 ANKRD28 GNAO1 MAPK10 ANKRD52 CACNA2D3	7.93e-05	610	129	11	EFO_0004761
Disease	non-word reading	ADCYAP1R1 SLC12A3 SETD3 EPHA4	2.16e-04	67	129	4	EFO_0005299
Disease	nephrotic syndrome	PHC1 TNFSF4 RRP12 GNAO1	2.70e-04	71	129	4	EFO_0004255
Disease	ETS domain-containing protein Elk-3 measurement	NLRP12 SLC35D2	2.81e-04	6	129	2	EFO_0801588
Disease	WAP four-disulfide core domain protein 3 measurement	NLRP12 SLC35D2	2.81e-04	6	129	2	EFO_0802220
Disease	acid ceramidase measurement	NLRP12 SLC35D2	2.81e-04	6	129	2	EFO_0801339
Disease	lon protease homolog, mitochondrial measurement	NLRP12 SLC35D2	2.81e-04	6	129	2	EFO_0801771
Disease	mitogen-activated protein kinase 8 measurement	NLRP12 MAPK10	2.81e-04	6	129	2	EFO_0020580
Disease	pulmonary alveolar proteinosis (is_implicated_in)	SFTPB CSF2RB	2.81e-04	6	129	2	DOID:12120 (is_implicated_in)
Disease	seasonal allergic rhinitis	GNAO1 DNAH5 TSLP	3.69e-04	32	129	3	EFO_0003956
Disease	cardiovascular measurement, left ventricular function	SLIT2 EPHA4	5.22e-04	8	129	2	EFO_0004295, EFO_0004298
Disease	McCune Albright syndrome (implicated_via_orthology)	GNAO1 GNAT1	5.22e-04	8	129	2	DOID:1858 (implicated_via_orthology)
Disease	Dermatitis, Atopic	CXCR3 MAPK8 TSLP	5.24e-04	36	129	3	C0011615
Disease	Eczema, Infantile	CXCR3 MAPK8 TSLP	5.24e-04	36	129	3	C0086196
Disease	epilepsy (implicated_via_orthology)	RHOG SLC12A3 MIB1 ATP1A4 KCNT1	7.67e-04	163	129	5	DOID:1826 (implicated_via_orthology)
Disease	reading and spelling ability	FLT3 IZUMO3 ADCYAP1R1 TNFSF4 SLC12A3	8.33e-04	166	129	5	EFO_0005301
Disease	secreted and transmembrane protein 1 measurement	NLRP12 GNAO1	8.34e-04	10	129	2	EFO_0021852
Disease	X-18913 measurement	ANKRD28 HACL1	1.02e-03	11	129	2	EFO_0800795
Disease	–	OLR1 TNFSF4	1.43e-03	13	129	2	608446
Disease	Myocardial infarction, susceptibility to	OLR1 TNFSF4	1.43e-03	13	129	2	cv:C1832662
Disease	Hypermetropia, Myopia	VIPR2 ANTXR2 RASGEF1B MAPK8 CACNA2D3	1.48e-03	189	129	5	HP_0000540, HP_0000545
Disease	tetralogy of Fallot (implicated_via_orthology)	PHC1 DNAH5	1.67e-03	14	129	2	DOID:6419 (implicated_via_orthology)
Disease	Kartagener syndrome (implicated_via_orthology)	SLIT2 DNAH5	1.67e-03	14	129	2	DOID:0050144 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	VIPR1 VIPR2 ADCYAP1R1 CHRNG ATP1A4	1.70e-03	195	129	5	DOID:1574 (implicated_via_orthology)
Disease	Churg-Strauss syndrome	GNAO1 TSLP	1.92e-03	15	129	2	EFO_0007208
Disease	Autosomal recessive primary microcephaly	PHC1 MFSD2A	1.92e-03	15	129	2	cv:C3711387
Disease	respiratory syncytial virus infectious disease (is_marker_for)	SFTPB TSLP	2.77e-03	18	129	2	DOID:1273 (is_marker_for)
Disease	Hypercholesterolemia, Familial	ABCA1 ABCG5	2.77e-03	18	129	2	C0020445
Disease	diabetic retinopathy	TNFSF4 GNAO1 KLHDC7A AGAP1	3.05e-03	136	129	4	EFO_0003770
Disease	primary ciliary dyskinesia (implicated_via_orthology)	SLIT2 DNAH5	3.09e-03	19	129	2	DOID:9562 (implicated_via_orthology)
Disease	refractive error	CACNA1D VIPR2 CHRNG ANTXR2 SNAP91 RASGEF1B	3.17e-03	326	129	6	MONDO_0004892
Disease	dehydroepiandrosterone sulphate measurement	ABCA13 ZKSCAN5 THADA	3.33e-03	68	129	3	EFO_0007001
Disease	neoplasm of mature B-cells	CYBC1 GNAO1	3.42e-03	20	129	2	EFO_0000096
Disease	cortical thickness	FBXW10 PRDM5 SLIT2 ABCG1 THADA CCDC88A SNAP91 SETD3 CACNA2D3 AGAP1 EPHA4 AGAP3	3.58e-03	1113	129	12	EFO_0004840
Disease	fetal hemoglobin measurement	PRDM5 ATP6V0A4	3.77e-03	21	129	2	EFO_0004576
Disease	perceived unattractiveness to mosquitos measurement	ANKRD66 CSF2RB GNAO1	3.91e-03	72	129	3	EFO_0008380
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ABCA1 H3C1 GNAO1 ABCG5 HTT	4.08e-03	239	129	5	EFO_0008317, EFO_0020945
Disease	Autosomal Recessive Primary Microcephaly	PHC1 MFSD2A	4.14e-03	22	129	2	C3711387

Protein segments in the cluster

Peptide	Gene	Start	Entry
ARYYLVQGLIEDCQL	KCTD13	121	Q8WZ19
CATYGLNVERVFQDV	AGAP3	231	Q96P47
FNINFYAGALLLACI	CXCR3	131	P49682
ETQGLCEYAIYVQAL	BBS4	61	Q96RK4
CATYGLNVERVFQDV	AGAP1	211	Q9UPQ3
DGYFQELLVAIVLCV	ANXA10	231	Q9UJ72
CANILIDAGADLNYV	ANKRD30B	121	Q9BXX2
FELFDQLYVLSQGQC	ABCG1	281	P45844
NNVDGVFEVALYCNV	CHRNG	116	P07510
VLFNCSIAENIAYGD	ABCB5	1101	Q2M3G0
VLIEERNVFCGTYNV	FBXW10	391	Q5XX13
QTAAILDREQGACLY	FAT4	1691	Q6V0I7
CEYFALFEEQGIGVQ	ABCA1	791	O95477
ACYNGQDVVVNELID	ANKRD28	246	O15084
ASVYCVGVLDFEQAQ	ANTXR2	171	P58335
IAQIYGQKACVAFLE	ANKRD66	116	B4E2M5
QNVTECILEDGFLYV	ABCA13	1351	Q86UQ4
IYCLETFVGDQVLEI	CPA2	16	P48052
KLFACYNDGVINLLE	SNAP91	206	O60641
NCVINRFQEELGYDL	FAM186B	46	Q8IYM0
ACYLGQDAVAIELVN	ANKRD52	246	Q8NB46
EEVLVYLNQIYCGQI	DHTKD1	116	Q96HY7
YLGIAEVRTLQQCLF	MSANTD2	476	Q6P1R3
TLVNDLLGQGYCVFL	PGBD4	316	Q96DM1
DIICVFSQYGEIVNI	RBMX2	51	Q9Y388
ICLRSGNYQEVIQIF	INTS8	331	Q75QN2
AFLKNVCLGLEDLQY	INTS8	441	Q75QN2
CYVDIPADFVNLQVN	HACL1	166	Q9UJ83
LAAIQEGENIFYLAV	PRDM5	96	Q9NQX1
LFQVYDIDVCARQGA	NOX5	101	Q96PH1
DFFNRINLIYGTICE	MOB3B	66	Q86TA1
VALIDCFLDGYVSQL	NUP133	806	Q8WUM0
EVYLCRELQLQGFVD	PADI6	316	Q6TGC4
GIVCAAYDAVLDRNV	MAPK10	76	P53779
ECLEFIAIIYGNTLQ	GNAT1	61	P11488
NVQVRDAGLYTCLAE	HMCN2	3561	Q8NDA2
NVYLAACGETLNIDF	KIAA1109	551	Q2LD37
LQCGIIYADNLVVVD	KCNT1	851	Q5JUK3
IAQCNLVILYEYVGN	DDX58	706	O95786
FYLAFQDVGACIALV	EPHA4	181	P54764
LDEYVALVDGVFLNQ	CCDC88A	36	Q3V6T2
VLNICEKDGTFDNIY	NAA50	96	Q9GZZ1
GDCFVLASDYLNALV	PCNX3	1371	Q9H6A9
AQGIVCAAYDAILER	MAPK8	36	P45983
ITDVDFIYQNEFLGC	DNAH8	1801	Q96JB1
FIYQNEFLGCTDRLV	DNAH8	1806	Q96JB1
GNEAQVCYFIIQLLL	MED23	876	Q9ULK4
DCYTFLQAEVANAGL	HERVK_113	211	P63132
ISNFAQEALGDVVYC	GCSH	71	P23434
INGYVFDSLQLSVCL	F8	636	P00451
ACEAYLVGLFEDTNL	H3C1	96	P68431
YGAVGVDLAFEQLLC	HSPA12B	351	Q96MM6
IQRGAVYAENCILAA	OLR1	246	P78380
IEYFIDVARECFNIG	RASGEF1B	286	Q0VAM2
LLIKDIYFLNEGCAN	RASGEF1B	376	Q0VAM2
DCYTFLQAEVANAGL	ERVK-7	211	P63135
DCYTFLQAEVANAGL	ERVK-6	211	Q9BXR3
YNELLFIIDTCQGAS	PIGK	196	Q92643
LINCYIRDNAAVDGI	NUP155	841	O75694
VAVLYCFLNGEVQAE	ADCYAP1R1	396	P41586
SQFQVGDLVQVCYDL	MIB1	331	Q86YT6
EQERLLCYNGEVLVF	FANCB	11	Q8NB91
IDFREYVIGLAVLCN	LPCAT2	411	Q7L5N7
CALGFFLQIYLLDVA	MFSD2A	61	Q8NA29
DCYTFLQAEVANAGL	ERVK-18	211	Q9QC07
NVLTFEDLLCFAYQV	FLT3	781	P36888
YLRNDIFEDAGILCQ	EXOC5	241	O00471
YFILINCGANVDLLD	CDC45	71	O75419
VVVYDFAQGCQIVDL	ESPL1	406	Q14674
NYCLLDSDQVFIGFV	HTT	1461	P42858
EGLLVLQQVGDYCFL	CSF2RB	811	P32927
CYLIDNNGFILVSED	CACNA2D3	856	Q8IZS8
FYLAFQDIGACLAIL	EPHA8	181	P29322
KIFNIQLEDEGIYEC	CNTN1	296	Q12860
FQALCNLYGAITIAQ	DDX19B	321	Q9UMR2
YVTGCLFVAVQNLED	CYBC1	51	Q9BQA9
CSEILVVNEFYGLNF	ABCG5	571	Q9H222
CDANVFIALYQSILG	CEP95	31	Q96GE4
RDVSNLGIFIYQLCN	ITM2A	206	O43736
GLDVLLEYLAFAQCS	FMNL1	146	O95466
FQCAVVDNLIYCVGR	KLHDC7A	716	Q5VTJ3
SVYDIICNLGFQLRE	ERMARD	16	Q5T6L9
AIVAAAAEILQCFGY	DHRS7B	121	Q6IAN0
AAEILQCFGYVDILV	DHRS7B	126	Q6IAN0
LVAFVLLNECVGTAY	SLC22A15	181	Q8IZD6
DFSCLVQRVYQEEGL	SCAP	911	Q12770
NAICGANYSIVDFLI	PPP1R13L	666	Q8WUF5
LLAGFYDACAQVEID	IFT140	1281	Q96RY7
FICGNYILLNVFLAI	CACNA1D	736	Q01668
IYQNEFLGCTDRLVI	DNAH5	1941	Q8TE73
CYVIGFLNASIQIGD	OR5B17	146	Q8NGF7
VLNNEAGLLEYFVNE	OSBPL11	81	Q9BXB4
GVFIYQGKLLDVCQN	IZUMO3	101	Q5VZ72
CLIQGLLYVDSVGFN	PANK1	366	Q8TE04
VFLQQIYEQLCLFED	SZT2	181	Q5T011
CYNFLREALEVAVAG	UTP6	381	Q9NYH9
AYVQGCERLEQAVLA	RNF207	196	Q6ZRF8
DYIFSLLNFVGLNIC	SLC35D2	291	Q76EJ3
LFILCEGNLDQKSYV	THADA	531	Q6YHU6
QCNQVLDDYFPLVID	SFTPB	111	P07988
SAFYILEQQCVGLAV	NBPF19	631	A0A087WUL8
AFYILEQQCVGLAID	NBPF19	876	A0A087WUL8
RSAFYILEQQCVGLA	NBPF19	1606	A0A087WUL8
SAFYILEQQCVGLAV	NBPF19	1851	A0A087WUL8
AFYILEQQCVGLAVD	NBPF19	2096	A0A087WUL8
RSAFYILEQQCVGLA	NBPF19	2826	A0A087WUL8
SAFYILEQQCVGLAV	NBPF19	3071	A0A087WUL8
AFYILEQQCVGLAVD	NBPF19	3316	A0A087WUL8
AVRYLECSALQQDGV	RHOG	151	P84095
YIRELVDIFVVGQQC	TAF1L	791	Q8IZX4
GFEILEYNSLEQLCI	MYH15	476	Q9Y2K3
AIIFCVALSGYDQVL	GNAO1	221	P09471
ECVALQDFRAGEQIY	SETD3	296	Q86TU7
VAQDYAQGVEIDCIL	SIPA1L3	876	O60292
FLCVTYERLLQQDNG	SETD1B	1696	Q9UPS6
NAFIICFYLEVGQLS	NKAIN1	76	Q4KMZ8
AAEINCNGVIEVINY	SRPK1	351	Q96SB4
FGSNQEEALQCYLVL	RRP12	891	Q5JTH9
EFNYLCPAIINQIDA	SLC39A6	286	Q13433
FYYELGVQIIEVCLA	SNF8	96	Q96H20
NVQYAGLDFEAILLQ	APEH	476	P13798
ILEFCSTFLLNGQEY	ATP1A4	521	Q13733
DCYTFLQAEVANAGL	ERVK-25	211	P63136
NALYCEFINRVNEVG	SUPT6H	956	Q7KZ85
FQVVLGYVELCAGNT	VPS50	286	Q96JG6
LDYECGIVSFVNVAQ	TRIM77	411	I1YAP6
ILYCFLNGEVQAELR	VIPR1	386	P32241
YTEQFLALIGQFICS	WASHC5	1091	Q12768
NSVIINCDGFYLISL	TNFSF4	91	P23510
ICRYDLAEIQAVFAG	SEMA4G	336	Q9NTN9
SLQFYSVENGDCLLV	TBCE	511	Q15813
LVSQVGACYQFNVVL	STOML1	306	Q9UBI4
YQESLLFLGLVAAVC	TTYH2	41	Q9BSA4
GLVVAVLYCFLNGEV	SCTR	381	P47872
VLYCFLNGEVQLEVQ	SCTR	386	P47872
DCYTFLQAEVANAGL	ERVK-10	211	P10266
DCYTFLQAEVANAGL	ERVK-11	211	Q9UQG0
ILIRGNQENVLTFYC	SLC12A3	1006	P55017
VGATVQYICDQGFVL	SEZ6	791	Q53EL9
QLVGLVLTYDFTNCD	TSLP	21	Q969D9
YEFIASLQGCQEIAE	PHC1	946	P78364
GCIRNLYINSELQDF	SLIT2	1306	O94813
GYCQGFNILAALILE	TBC1D30	336	Q9Y2I9
LTFQAYEQILGITCV	ARHGAP8	311	P85298
FQGLVVAVLYCFLNS	VIPR2	366	P41587
FLQVEAAYCCVAELG	ATP6V0A4	16	Q9HBG4
GNIILEYLNDEEQFC	ZFAND1	246	Q8TCF1
EGAYFVAQLLAICFQ	TMEM72	56	A0PK05
FIYCLVLLAFANGLN	TRPC4	521	Q9UBN4
CGEIFFQYVSLIEHQ	ZKSCAN5	666	Q9Y2L8
QICIQLEGIGQFAYA	TTI1	626	O43156
AVNCLLGNVFYERLA	AGL	396	P35573
AEYGCILEIRNVQFF	LONRF3	606	Q496Y0
LQQGSLEFFSCLYEI	NLRP12	606	P59046
LIDFYDNQPCINLIE	MYO5A	486	Q9Y4I1