Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	IPO7 IQGAP2 STXBP5L RTKN ARHGEF17 ALS2CL RGS12 RAPGEF3 HPS4 HERC1 ELMOD1	1.22e-04	507	111	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	IPO7 IQGAP2 STXBP5L RTKN ARHGEF17 ALS2CL RGS12 RAPGEF3 HPS4 HERC1 ELMOD1	1.22e-04	507	111	11	GO:0030695
GeneOntologyMolecularFunction	ATPase binding	ADCY10 ANK1 TCIRG1 RUVBL1 PIK3R1	3.43e-04	108	111	5	GO:0051117
HumanPheno	Patellar subluxation	COL12A1 USP9X YY1	1.66e-05	7	41	3	HP:0010499
Domain	Runt	RUNX2 RUNX1	1.01e-04	3	109	2	PF00853
Domain	RUNT	RUNX2 RUNX1	1.01e-04	3	109	2	PS51062
Domain	TF_Runt-rel_RUNX	RUNX2 RUNX1	1.01e-04	3	109	2	IPR016554
Domain	RunxI	RUNX2 RUNX1	1.01e-04	3	109	2	PF08504
Domain	Runt_dom	RUNX2 RUNX1	1.01e-04	3	109	2	IPR013524
Domain	RunxI_C_dom	RUNX2 RUNX1	1.01e-04	3	109	2	IPR013711
Domain	MAPK_ERK3/4	MAPK4 MAPK6	1.01e-04	3	109	2	IPR008350
Domain	Runx_central_dom	RUNX2 RUNX1	1.01e-04	3	109	2	IPR027384
Domain	-	RUNX2 RUNX1	1.01e-04	3	109	2	4.10.770.10
Domain	AML1_Runt	RUNX2 RUNX1	1.01e-04	3	109	2	IPR000040
Domain	p53/RUNT-type_TF_DNA-bd	RUNX2 RUNX1	4.99e-04	6	109	2	IPR012346
Domain	MA3	EIF4G1 EIF4G3	4.99e-04	6	109	2	SM00544
Domain	-	RUNX2 RUNX1	4.99e-04	6	109	2	2.60.40.720
Domain	MA3	EIF4G1 EIF4G3	4.99e-04	6	109	2	PF02847
Domain	Initiation_fac_eIF4g_MI	EIF4G1 EIF4G3	4.99e-04	6	109	2	IPR003891
Domain	MI	EIF4G1 EIF4G3	4.99e-04	6	109	2	PS51366
Domain	eIF5C	EIF4G1 EIF4G3	6.95e-04	7	109	2	SM00515
Domain	Syndecan	NRXN1 SDC4	6.95e-04	7	109	2	PF01034
Domain	W2	EIF4G1 EIF4G3	6.95e-04	7	109	2	PF02020
Domain	W2	EIF4G1 EIF4G3	6.95e-04	7	109	2	PS51363
Domain	Syndecan/Neurexin_dom	NRXN1 SDC4	6.95e-04	7	109	2	IPR027789
Domain	W2_domain	EIF4G1 EIF4G3	6.95e-04	7	109	2	IPR003307
Domain	ARM-type_fold	DNAJC13 IPO7 USP9X ECPAS URB1 EIF4G1 STKLD1 EIF4G3	8.41e-04	339	109	8	IPR016024
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO7 FN1 DHX37 USP9X PABPC4 ECPAS PPM1G RPL10A CSDE1 URB1 POP1 EIF4G1 NUP133 MACF1 EIF4G3 ZBTB11 SF3B2 FTSJ3	3.67e-12	653	112	18	22586326
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DNAJC13 IQGAP2 DHX37 PABPC4 RPL10A CSDE1 URB1 RUVBL1 POP1 EIF4G1 NUP133 CKAP2L MACF1 EIF4G3 ZBTB11 FTSJ3	3.08e-09	759	112	16	35915203
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HBS1L DNAJC13 SETX IPO7 FN1 DHX37 RUNX1 RPL10A CSDE1 URB1 RUVBL1 POP1 EIF4G1 NUP133 MACF1 ALDH1B1 SF3B2 SDC4 FTSJ3	6.44e-08	1353	112	19	29467282
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	HBS1L IPO7 USP9X CARMIL1 PABPC4 ECPAS PPM1G RPL10A CSDE1 RUVBL1 EIF4G1 MACF1 EIF4G3 SF3B2	7.07e-08	708	112	14	39231216
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DMXL2 FN1 KDM5A USP9X RUNX1 RXRG CSDE1 OTOF PIK3R1 HPS4 USP32 EIF4G1 MACF1 EIF4G3 ZBTB11 SMURF2 SF3B2 KLHL4	1.55e-07	1285	112	18	35914814
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	HBS1L DHX58 DHX37 PABPC4 PPM1G RPL10A CSDE1 RUVBL1 POP1 EIF4G1 SF3B2	3.69e-07	469	112	11	37314180
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	USP9X YY1 RPL10A URB1 RUVBL1 NUP133 SF3B2 FTSJ3	6.10e-07	220	112	8	34091597
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	IPO7 IQGAP2 RPL10A URB1 RUVBL1 EIF4G1 EIF4G3 SF3B2	6.32e-07	221	112	8	29991511
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ANK1 FN1 DHX37 USP9X CARMIL1 AK9 ECPAS RGS12 USP32 HERC1 HYDIN	6.52e-07	497	112	11	36774506
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	DNAJC13 DHX37 PABPC4 YY1 RPL10A PRR12 URB1 RUVBL1 POP1 EIF4G1 NUP133 SF3B2 FTSJ3	3.58e-06	847	112	13	35850772
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HBS1L IFT22 DHX37 CARMIL1 ECPAS RTKN RGS12 CSDE1 PPP1R7 RUVBL1 RASEF ALDH1B1 FTSJ3	3.86e-06	853	112	13	28718761
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	HBS1L IPO7 USP9X RPS6KA1 PABPC4 ECPAS PPM1G CSDE1 PPP1R7 RUVBL1 POP1 EIF4G1 NT5C2 NUP133 MACF1 ALDH1B1 HERC1	4.19e-06	1455	112	17	22863883
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	HBS1L DMXL2 IPO7 IQGAP2 USP9X ECPAS RPL10A RUVBL1 MACF1 EIF4G3	5.09e-06	498	112	10	36634849
Pubmed	A protein interaction landscape of breast cancer.	USP9X PABPC4 RUNX2 RUNX1 ECPAS PPM1G RPL10A PIK3R1 ABRAXAS1 MACF1 FTSJ3	6.74e-06	634	112	11	34591612
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	HBS1L DMXL2 SETX DHX37 RPS6KA1 CSDE1 PRR12 DDHD1 POP1 ZBTB11 SF3B2	8.51e-06	650	112	11	38777146
Pubmed	The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.	RUNX2 RUNX1	1.03e-05	2	112	2	9233771
Pubmed	The Leukemia Inhibitory Factor Receptor Gene Is a Direct Target of RUNX1.	RUNX1 LIFR	1.03e-05	2	112	2	26060100
Pubmed	Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage.	FN1 ACAN	1.03e-05	2	112	2	21224775
Pubmed	Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.	EIF4G1 EIF4G3	1.03e-05	2	112	2	31999954
Pubmed	eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation.	EIF4G1 EIF4G3	1.03e-05	2	112	2	10872469
Pubmed	The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.	MAPK4 MAPK6	1.03e-05	2	112	2	25002529
Pubmed	The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation.	MAPK4 MAPK6	1.03e-05	2	112	2	32139423
Pubmed	Lnc-PIK3R1, transcriptionally suppressed by YY1, inhibits hepatocellular carcinoma progression via the Lnc-PIK3R1/miR-1286/GSK3β axis.	YY1 PIK3R1	1.03e-05	2	112	2	38744342
Pubmed	YY1 represses the transcriptional activity of Runx2 in C2C12 cells.	RUNX2 YY1	1.03e-05	2	112	2	24325869
Pubmed	Syndecan-4 and fibronectin in osteosarcoma.	FN1 SDC4	1.03e-05	2	112	2	22531343
Pubmed	Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.	RUNX2 RUNX1	1.03e-05	2	112	2	16059634
Pubmed	RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells.	RUNX2 RUNX1	1.03e-05	2	112	2	32180230
Pubmed	Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.	RUNX2 RUNX1	1.03e-05	2	112	2	17290219
Pubmed	Smurf2 regulates the degradation of YY1.	YY1 SMURF2	1.03e-05	2	112	2	24803334
Pubmed	ERK3 is required for metaphase-anaphase transition in mouse oocyte meiosis.	MAPK4 MAPK6	1.03e-05	2	112	2	20927325
Pubmed	Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.	RUNX2 RUNX1	1.03e-05	2	112	2	35551452
Pubmed	Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation.	RUNX2 SMURF2	1.03e-05	2	112	2	24961731
Pubmed	Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.	RUNX2 RUNX1	1.03e-05	2	112	2	23321257
Pubmed	Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice.	RUNX2 ACAN	1.03e-05	2	112	2	28539595
Pubmed	Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.	RUNX2 RUNX1	1.03e-05	2	112	2	17533052
Pubmed	A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.	RUNX2 RUNX1	1.03e-05	2	112	2	27634876
Pubmed	The non-classical MAP kinase ERK3 controls T cell activation.	MAPK4 MAPK6	1.03e-05	2	112	2	24475167
Pubmed	Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3.	MAPK4 MAPK6	1.03e-05	2	112	2	7969157
Pubmed	Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene.	RUNX2 RUNX1	1.03e-05	2	112	2	10903914
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HBS1L SETX FN1 B3GNT5 IQGAP2 URB1 PIK3R1 DDHD1 FECH POP1 PAN2 MACF1 HERC1 NPAT	1.06e-05	1084	112	14	11544199
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ARHGEF17 YY1 OTOF POP1 MACF1 HERC1 SF3B2	1.13e-05	234	112	7	36243803
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	IPO7 IQGAP2 DHX37 USP9X PABPC4 PPM1G RPL10A CSDE1 URB1 RUVBL1 FECH EIF4G1 NUP133 ALDH1B1 SF3B2	1.27e-05	1257	112	15	37317656
Pubmed	Human transcription factor protein interaction networks.	KDM5A DHX37 USP9X PABPC4 GMEB2 YY1 TFE3 PPM1G RPL10A PRR12 EIF4G1 NT5C2 ZFHX3 HERC1 NPAT FTSJ3	1.40e-05	1429	112	16	35140242
Pubmed	Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development.	RUNX2 RUNX1 ACAN	1.44e-05	15	112	3	26890219
Pubmed	Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.	FN1 RUNX2 ACAN	1.44e-05	15	112	3	38018454
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	DNAJC13 IPO7 RUNX1 RPL10A URB1 NUP133 SF3B2 FTSJ3	1.51e-05	340	112	8	29478914
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	DHX37 USP9X PABPC4 PPM1G RPL10A CSDE1 RUVBL1 FECH POP1 EIF4G1 MAPK4 ZBTB11 SF3B2	1.54e-05	971	112	13	33306668
Pubmed	Large-scale concatenation cDNA sequencing.	KDM5A USP9X ETV1 ECPAS METTL6 CSDE1 RAPGEF3 NPTXR NUP133 HERC1	1.59e-05	568	112	10	9110174
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	IQGAP2 DHX37 USP9X PABPC4 ECPAS TFE3 PPP1R7 RUVBL1 PIK3R1 EIF4G1 NUP133 HERC1 EIF4G3 SF3B2 FTSJ3	1.63e-05	1284	112	15	17353931
Pubmed	A "double adaptor" method for improved shotgun library construction.	KDM5A USP9X ETV1 ECPAS METTL6 CSDE1 RAPGEF3 NPTXR NUP133 HERC1	1.74e-05	574	112	10	8619474
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SETX CEBPD KDM5A RUNX1 YY1 TFE3 RPL10A PRR12 URB1 RUVBL1 ABRAXAS1 POP1 NUP133 SF3B2 FTSJ3	1.79e-05	1294	112	15	30804502
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	ZNF787 HBS1L DNAJC13 COL12A1 SETX IPO7 DHX37 PABPC4 ARHGEF17 CSDE1 POP1 NT5C2 MACF1 SDC4 RCN3	1.83e-05	1297	112	15	33545068
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	IPO7 IQGAP2 USP9X PABPC4 ECPAS PPM1G RPL10A PPP1R7 RUVBL1 EIF4G1 MACF1 EIF4G3 SF3B2 FTSJ3	2.02e-05	1149	112	14	35446349
Pubmed	Cbfb regulates bone development by stabilizing Runx family proteins.	RUNX2 RUNX1 ACAN	2.14e-05	17	112	3	25262822
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HBS1L ANK1 KDM5A DHX37 PABPC4 GMEB2 YY1 RPL10A CSDE1 RUVBL1 FECH POP1 EIF4G1 SF3B2 FTSJ3	2.21e-05	1318	112	15	30463901
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DNAJC13 STXBP5L CARMIL1 ETV1 DGKH ECPAS CSDE1 FECH NT5C2 FNIP1 MACF1 RASEF ZFHX3 MAPK6 EIF4G3 SMURF2	2.32e-05	1489	112	16	28611215
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	KDM5A PABPC4 RPL10A PPP1R7 PRR12 RUVBL1 ABRAXAS1 FTSJ3	2.32e-05	361	112	8	30344098
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZNF787 HBS1L SETX KDM5A PABPC4 CSDE1 PRR12 URB1 MICALL2 POP1 EIF4G1 MACF1 ZFHX3 EIF4G3 ZBTB11 SDC4	2.47e-05	1497	112	16	31527615
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	IPO7 USP9X CSDE1 EIF4G1 ZBTB11 SF3B2	2.60e-05	179	112	6	36261009
Pubmed	Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.	RUNX2 ACAN	3.08e-05	3	112	2	31189030
Pubmed	Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors.	RUNX2 RUNX1	3.08e-05	3	112	2	19585539
Pubmed	Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E.	EIF4G1 EIF4G3	3.08e-05	3	112	2	20212144
Pubmed	Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development.	RUNX2 RUNX1	3.08e-05	3	112	2	14516670
Pubmed	Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection.	RUNX2 RUNX1	3.08e-05	3	112	2	12218099
Pubmed	RUNX1 regulates SMAD1 by transcriptionally activating the expression of USP9X, regulating the activation of hepatic stellate cells and liver fibrosis.	USP9X RUNX1	3.08e-05	3	112	2	33933467
Pubmed	Malignant transformation of salivary gland pleomorphic adenoma: proof of principle.	LIFR PIK3R1	3.08e-05	3	112	2	34390320
Pubmed	Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone.	RUNX2 SMURF2	3.08e-05	3	112	2	23969857
Pubmed	Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex.	CEBPD YY1	3.08e-05	3	112	2	18753137
Pubmed	MiR-195 inhibits the ubiquitination and degradation of YY1 by Smurf2, and induces EMT and cell permeability of retinal pigment epithelial cells.	YY1 SMURF2	3.08e-05	3	112	2	34267179
Pubmed	CCAAT/enhancer-binding protein delta activates the Runx2-mediated transcription of mouse osteocalcin II promoter.	CEBPD RUNX2	3.08e-05	3	112	2	16720721
Pubmed	Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.	MAPK4 MAPK6	3.08e-05	3	112	2	16973613
Pubmed	RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region.	RUNX2 RUNX1	3.08e-05	3	112	2	16237704
Pubmed	AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.	RUNX2 RUNX1	3.08e-05	3	112	2	7835892
Pubmed	Structure of Yin Yang 1 oligomers that cooperate with RuvBL1-RuvBL2 ATPases.	YY1 RUVBL1	3.08e-05	3	112	2	24990942
Pubmed	A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation.	EIF4G1 EIF4G3	3.08e-05	3	112	2	9857202
Pubmed	Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor.	RUNX2 RUNX1	3.08e-05	3	112	2	8497254
Pubmed	AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene.	RUNX2 RUNX1	3.08e-05	3	112	2	10521447
Pubmed	Fibronectin induced ITGβ1/FAK-dependent apoptotic pathways determines the fate of degenerative NP cells.	FN1 SDC4	3.08e-05	3	112	2	30370584
Pubmed	Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.	MAPK4 MAPK6	3.08e-05	3	112	2	18720373
Pubmed	C5a-regulated CCAAT/enhancer-binding proteins β and δ are essential in Fcγ receptor-mediated inflammatory cytokine and chemokine production in macrophages.	CEBPD C5	3.08e-05	3	112	2	22147692
Pubmed	Deletion of Runx2 in condylar chondrocytes disrupts TMJ tissue homeostasis.	RUNX2 ACAN	3.08e-05	3	112	2	30387127
Pubmed	Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.	RPS6KA1 ETV1	3.08e-05	3	112	2	12213813
Pubmed	The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).	RUNX2 RUNX1	3.08e-05	3	112	2	8384306
Pubmed	The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.	RUNX2 RUNX1	3.08e-05	3	112	2	12217689
Pubmed	FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.	RUNX2 SMURF2	3.08e-05	3	112	2	38810422
Pubmed	Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.	RUNX2 RUNX1	3.08e-05	3	112	2	15713794
Pubmed	Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.	RUNX2 RUNX1	3.08e-05	3	112	2	22032690
Pubmed	Genetic regulation of the RUNX transcription factor family has antitumor effects.	RUNX2 RUNX1	3.08e-05	3	112	2	28530640
Pubmed	FNDC5/irisin facilitates muscle-adipose-bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2.	RUNX2 RUNX1	3.08e-05	3	112	2	35124008
Pubmed	Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2.	RUNX2 RUNX1	3.08e-05	3	112	2	15051730
Pubmed	Identification and comparative analysis of a second runx3 promoter.	RUNX2 RUNX1	3.08e-05	3	112	2	11483356
Pubmed	PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.	RUNX2 RUNX1	3.08e-05	3	112	2	8035830
Pubmed	RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.	RUNX2 RUNX1	3.08e-05	3	112	2	19020999
Pubmed	Osteopetrosis, osteopetrorickets and hypophosphatemic rickets differentially affect dentin and enamel mineralization.	TCIRG1 PHEX	3.08e-05	3	112	2	23174213
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	DNAJC13 SETX USP9X PABPC4 TCIRG1 RPL10A RUVBL1 EIF4G1 SF3B2 FTSJ3	3.13e-05	615	112	10	31048545
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	IPO7 PABPC4 ECPAS RPL10A CSDE1 RUVBL1 EIF4G1 NUP133 SF3B2	3.30e-05	494	112	9	26831064
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SETX IPO7 FN1 IQGAP2 KDM5A DHX37 PABPC4 CSDE1 RUVBL1 POP1 EIF4G1 CKAP2L C5 SF3B2 FTSJ3	3.48e-05	1371	112	15	36244648
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	PABPC4 RUVBL1 EIF4G1 EIF4G3	4.05e-05	59	112	4	32382008
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DNAJC13 IPO7 USP9X ECPAS RPL10A CSDE1 RUVBL1 EIF4G1 NUP133 SF3B2	4.25e-05	638	112	10	33239621
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZNF787 DMXL2 DNAJC13 SETX KDM5A DHX37 RPL10A RUVBL1 NRXN1 EIF4G1 PAN2 MACF1 SF3B2	4.70e-05	1082	112	13	38697112
Interaction	SIRT7 interactions	IPO7 FN1 DHX37 USP9X PABPC4 ECPAS PPM1G RPL10A CSDE1 URB1 POP1 EIF4G1 NUP133 MACF1 EIF4G3 ZBTB11 SF3B2 FTSJ3	1.26e-07	744	111	18	int:SIRT7
Interaction	HECTD1 interactions	HBS1L DNAJC13 IPO7 IQGAP2 DHX37 USP9X PABPC4 RPL10A CSDE1 URB1 RUVBL1 FECH POP1 EIF4G1 NUP133 CKAP2L MACF1 EIF4G3 ZBTB11 FTSJ3	3.84e-07	984	111	20	int:HECTD1
Interaction	GSPT1 interactions	HBS1L PABPC4 PPM1G RPL10A CSDE1 RUVBL1 PIK3R1 EIF4G1 PAN2 EIF4G3	7.49e-06	306	111	10	int:GSPT1
Interaction	SOX2 interactions	ZNF787 DNAJC13 CEBPD IPO7 FN1 USP9X PABPC4 RUNX2 RUNX1 YY1 TFE3 RPL10A PRR12 RUVBL1 POP1 CKAP2L MACF1 ZFHX3 C5 EIF4G3 FTSJ3	2.85e-05	1422	111	21	int:SOX2
Interaction	RARA interactions	FN1 KDM5A RUNX1 RXRG RUVBL1 PIK3R1 DSG4 MAPK6	3.29e-05	223	111	8	int:RARA
Interaction	MEN1 interactions	DNAJC13 DHX37 PABPC4 RUNX2 RUNX1 ECPAS ARHGEF17 YY1 RPL10A PRR12 URB1 RUVBL1 POP1 EIF4G1 NUP133 SF3B2 FTSJ3	4.66e-05	1029	111	17	int:MEN1
Interaction	FBL interactions	IPO7 FN1 DHX37 PABPC4 TFE3 RPL10A CSDE1 URB1 RUVBL1 POP1 EIF4G1 PAN2 FTSJ3	5.04e-05	639	111	13	int:FBL
Interaction	SMAD1 interactions	IPO7 USP9X HBP1 RUNX2 RUNX1 YY1 SMURF2 SF3B2	6.04e-05	243	111	8	int:SMAD1
GeneFamily	Mitogen-activated protein kinases	MAPK4 MAPK6	1.35e-03	13	77	2	651
GeneFamily	Ubiquitin specific peptidases	USP9X USP32 PAN2	1.75e-03	56	77	3	366
GeneFamily	INO80 complex \|SRCAP complex	YY1 RUVBL1	1.81e-03	15	77	2	595
GeneFamily	DEAH-box helicases	DHX58 DHX37	2.07e-03	16	77	2	500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DMXL2 DNAJC13 SETX IPO7 KDM5A USP9X RUNX1 YY1 NT5C2 NUP133 MACF1 ZFHX3 MAPK6 EIF4G3 ZBTB11 SMURF2 NPAT	1.37e-07	856	112	17	M4500
Coexpression	GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_DN	DHX58 KDM5A HBP1 PPM1G RUVBL1 POP1 EIF4G3 FTSJ3	2.32e-06	199	112	8	M7099
Coexpression	TABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_MYELOID_CELL_AGEING	DNAJC13 CEBPD RUNX1 PPM1G HPS4 EIF4G3 SF3B2 SDC4	9.22e-06	240	112	8	MM3678
Coexpression	GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	CARMIL1 URB1 NPTXR ACAN NUP133 MACF1 ZFHX3	2.27e-05	197	112	7	M8980
Coexpression	GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP	SETX CEBPD IPO7 CARMIL1 RUNX2 ST14 SDC4	2.50e-05	200	112	7	M7147
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	DMXL2 DNAJC13 SETX FAM185A FN1 ETV1 MAGEB16 URB1 RUVBL1 ABRAXAS1 POP1 NUP133 HERC1 ZSWIM7 SDC4 FTSJ3	3.32e-06	810	108	16	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	DMXL2 DNAJC13 SETX FAM185A KDM5A USP9X MAGEB16 URB1 ABRAXAS1 DDHD1 USP32 NUP133 FNIP1 HERC1 ZSWIM7 NPAT	3.89e-06	820	108	16	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 DHX58 FN1 CARMIL1 ACAN SDC4 RCN3	6.81e-07	197	112	7	4b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 DHX58 FN1 CARMIL1 ACAN SDC4 RCN3	6.81e-07	197	112	7	ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR ACAN RCN3	7.29e-07	199	112	7	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR ACAN RCN3	7.29e-07	199	112	7	bf138cc692df727e087d140c014149ee5da00d9d
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 FN1 RUNX1 PIK3R1 ACAN SDC4 RCN3	7.54e-07	200	112	7	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 FN1 RUNX1 PIK3R1 ACAN SDC4 RCN3	7.54e-07	200	112	7	d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 FN1 RUNX1 PIK3R1 ACAN SDC4 RCN3	7.54e-07	200	112	7	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 FN1 RUNX1 PIK3R1 ACAN SDC4 RCN3	7.54e-07	200	112	7	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS6KA1 CARMIL1 AMDHD1 RUNX2 LIFR LEFTY1	4.89e-06	172	112	6	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS6KA1 CARMIL1 AMDHD1 RUNX2 LIFR LEFTY1	4.89e-06	172	112	6	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FN1 RUNX2 PHEX LIFR NPTXR RCN3	5.96e-06	178	112	6	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP9X DGKH DDHD1 MACF1 HERC1 ZBTB11	8.14e-06	188	112	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	FN1 ETV1 PHEX LIFR PIK3R1 MACF1	8.65e-06	190	112	6	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FN1 ETV1 ARHGEF17 METTL6 PIK3R1 MACF1	8.91e-06	191	112	6	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR ACAN	8.91e-06	191	112	6	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR ACAN	8.91e-06	191	112	6	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X CSDE1 LIFR MACF1 ZFHX3 HYDIN	9.18e-06	192	112	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 USP9X HBP1 RUNX1 CSDE1 SDC4	1.06e-05	197	112	6	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR RCN3	1.06e-05	197	112	6	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN RCN3	1.06e-05	197	112	6	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN RCN3	1.06e-05	197	112	6	63b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN RCN3	1.06e-05	197	112	6	fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN RCN3	1.09e-05	198	112	6	1f956e369e00d37835095a001db4b62a79014532
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN RCN3	1.09e-05	198	112	6	dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR NRXN1 ACAN	1.09e-05	198	112	6	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR RCN3	1.09e-05	198	112	6	6a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR NRXN1 ACAN	1.09e-05	198	112	6	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 DHX58 FN1 CARMIL1 ACAN SDC4	1.09e-05	198	112	6	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR RCN3	1.16e-05	200	112	6	16a7c398626b6e82b394eb3ef013bda3a788659d
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR RCN3	1.16e-05	200	112	6	780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR RCN3	1.16e-05	200	112	6	28dd127787a57276253548d1f030814b1af64481
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IQGAP2 ETV1 RUNX2 LEFTY1 NPTXR	1.95e-05	130	112	5	c70fb77324916d220d842a575558a8245c276599
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IQGAP2 RPS6KA1 TCIRG1 RUNX2 LEFTY1	5.93e-05	164	112	5	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IQGAP2 RPS6KA1 TCIRG1 RUNX2 LEFTY1	5.93e-05	164	112	5	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS6KA1 CARMIL1 RUNX2 LEFTY1 SDC4	6.28e-05	166	112	5	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS6KA1 CARMIL1 RUNX2 LEFTY1 SDC4	6.28e-05	166	112	5	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ETV1 LEFTY1 FAM167A RCN3	6.83e-05	169	112	5	7be742160e3e7e6c8f86b037be4e425f4d4cf663
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ETV1 DGKH ST14 ZFHX3	6.83e-05	169	112	5	ccb7b2daa65cb5f4c1e7a48b3bcdf0cb8f7675c3
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ETV1 LEFTY1 FAM167A RCN3	6.83e-05	169	112	5	4ccf5cfa4fe72d3af056d658460a9ccaa07b01be
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 AMDHD1 RUNX2 LIFR LEFTY1	7.03e-05	170	112	5	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	Control-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	FN1 B3GNT5 PIK3R1 ANKDD1A MAPK6	7.03e-05	170	112	5	9e328e1f904c77dcce8aee4df775d7f0ac725775
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 AMDHD1 RUNX2 LIFR LEFTY1	7.03e-05	170	112	5	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	FN1 CARMIL1 DGKH ACAN ZFHX3	7.23e-05	171	112	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	IQCH B3GNT5 DHX37 ECPAS MAPK6	7.43e-05	172	112	5	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 ALS2CL LEFTY1 FAM167A RASEF	8.06e-05	175	112	5	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	RUNX2 RUNX1 LIFR SDC4 RCN3	8.28e-05	176	112	5	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	8.28e-05	176	112	5	d4075796c38b775fe721abb47426e662a0d415e3
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 KDM5A ALS2CL FAM167A MAPK4	8.28e-05	176	112	5	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ETV1 DGKH ST14 RASEF ZFHX3	8.28e-05	176	112	5	ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A B3GNT5 DHX37 ECPAS FAM167A	8.50e-05	177	112	5	c2b8a3a149d70f77612759dea34df9e43953c566
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A B3GNT5 DHX37 ECPAS FAM167A	8.50e-05	177	112	5	384f841aa7b2d05815af7885e481f5affc55d897
ToppCell	facs-Thymus-Epithelium-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM185A B3GNT5 DHX37 ECPAS FAM167A	8.50e-05	177	112	5	0e9e44119653abfd270e602e5e477a15e774638f
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV1 RTKN RXRG NRXN1 MAPK4	8.73e-05	178	112	5	ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	8.96e-05	179	112	5	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	8.96e-05	179	112	5	1757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	8.96e-05	179	112	5	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	9.20e-05	180	112	5	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	9.20e-05	180	112	5	64f01494a4052186773720e10b4e7c724ff94547
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPD FN1 RUNX2 RTP4 RCN3	9.20e-05	180	112	5	12537d8a569faa69f474284d2c201475722b8ca1
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	9.44e-05	181	112	5	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	9.44e-05	181	112	5	e2481291c236105774c53883e6f20da11941df9b
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	9.44e-05	181	112	5	fb64da1dde37fe6ba7de2586cd58848ac1974f24
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADCY10 ANK1 FECH HERC1 TBCEL	9.69e-05	182	112	5	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 IQGAP2 RXRG NRXN1 SLC49A3	9.69e-05	182	112	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	Immune_cells-Dendritic_cells\|Immune_cells / Lineage and Cell class	RPS6KA1 CARMIL1 RUNX2 LIFR LEFTY1	9.69e-05	182	112	5	99c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX RCN3	9.94e-05	183	112	5	27a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ANK1 STXBP5L NRXN1 HYDIN	1.02e-04	184	112	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ANK1 STXBP5L NRXN1 HYDIN	1.02e-04	184	112	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ANK1 STXBP5L NRXN1 HYDIN	1.02e-04	184	112	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ALS2CL RGS12 MAPK4 HYDIN KLHL4	1.02e-04	184	112	5	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ALS2CL RGS12 MAPK4 HYDIN KLHL4	1.02e-04	184	112	5	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 IQGAP2 RGS12 RXRG NPTXR	1.05e-04	185	112	5	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL1 RUNX2 LIFR LEFTY1 SDC4	1.05e-04	185	112	5	65dcb0a7ee64990a34a87c167b44497107f035ee
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DMXL2 RUNX2 URB1 DDHD1 MACF1	1.07e-04	186	112	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV1 RTKN RXRG NRXN1 MICALL2	1.13e-04	188	112	5	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN	1.13e-04	188	112	5	116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	FN1 ETV1 PHEX MACF1 RCN3	1.13e-04	188	112	5	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV1 RTKN RXRG NRXN1 MICALL2	1.13e-04	188	112	5	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	(3)_Chondrocytes-(31)_Chondro-hyper\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	COL12A1 RUNX2 RPL10A LIFR ACAN	1.16e-04	189	112	5	864526ed3e338c0353d10699f650f88c065ce72b
ToppCell	ASK454-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	IFT22 B3GNT5 ABRAXAS1 FECH HYDIN	1.19e-04	190	112	5	5cea6480f08253d7adf484e511d3fdfa96641268
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 FECH ALDH1B1 TBCEL	1.19e-04	100	112	4	f305bc37f97617007b59bf06d288dd14c3c06e42
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 LIFR ACAN	1.22e-04	191	112	5	98b907f8fa024cf32e462323b782c5a371327bbd
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CEBPD FN1 SDC4 RCN3	1.22e-04	191	112	5	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 IQGAP2 RUNX1 RPL10A SDC4	1.22e-04	191	112	5	4fcbc214853e115608b3be7b35639247ae41c9dc
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FN1 ALS2CL RAPGEF3 ACSM2A KLHL4	1.25e-04	192	112	5	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IQGAP2 RGS12 RXRG NPTXR MAPK4	1.25e-04	192	112	5	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ETV1 PHEX MACF1 RCN3	1.28e-04	193	112	5	027e098ad018e782287f84eee0f77551018f2196
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ETV1 PHEX MACF1 RCN3	1.28e-04	193	112	5	c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 ETV1 PIK3R1 MACF1 RCN3	1.31e-04	194	112	5	f15e81ff12525523c62d13105cf264ea72205e2e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-\|lymph-node_spleen / Manually curated celltypes from each tissue	CEBPD IQGAP2 TCIRG1 RUNX2 PIK3R1	1.31e-04	194	112	5	8a596f25f6bfa5baaa2f52d80ad92f2925713398
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CEBPD RUNX1 SDC4 RCN3	1.34e-04	195	112	5	d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 ETV1 PHEX MACF1 RCN3	1.34e-04	195	112	5	cbe518b465b4ef32797ae6b608219207c08493df
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 RUNX2 PHEX LIFR	1.34e-04	195	112	5	30ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCell	PND03-Mesenchymal-Mesenchymal_structural\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 ETV1 PHEX MACF1 RCN3	1.34e-04	195	112	5	136b06b0931a69b1241101f68c01c44c70365fd9
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X NRXN1 FNIP1 MACF1 HERC1	1.34e-04	195	112	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	facs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 CARMIL1 RGS12 RAPGEF3 ZFHX3	1.34e-04	195	112	5	7e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X NRXN1 FNIP1 MACF1 HERC1	1.34e-04	195	112	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 USP9X HBP1 RUNX1 CSDE1	1.37e-04	196	112	5	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FN1 ETV1 PHEX LIFR MACF1	1.37e-04	196	112	5	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	E17.5-Mesenchymal\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FN1 ETV1 PIK3R1 MACF1 RCN3	1.37e-04	196	112	5	b4ee991445b612506372b9361ebfe72cb59b811e
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	FN1 KDM5A ETV1 HBP1 PPP1R7 HPS4 C5 RCN3	4.65e-06	192	111	8	1221_UP
Drug	Tyloxapol [25301-02-4]; Down 200; 4uM; MCF7; HT_HG-U133A	SETX KDM5A GMEB2 ALS2CL YY1 MICALL2 ZFHX3 ALDH1B1	5.62e-06	197	111	8	5672_DN
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; PC3; HT_HG-U133A	ZNF787 RPS6KA1 RUNX1 ARHGEF17 RGS12 URB1 ZFHX3 RCN3	5.83e-06	198	111	8	5107_UP
Drug	Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A	FN1 ARHGEF17 ALS2CL YY1 RGS12 URB1 ALDH1B1 NPAT	5.83e-06	198	111	8	5272_DN
Disease	serum albumin measurement	HBS1L DNAJC13 PABPC4 TCIRG1 HBP1 RUNX1 RGS12 PRR12 PIK3R1 MACF1 RCN3	1.37e-05	592	110	11	EFO_0004535
Disease	platelet measurement	ZNF787 HBS1L IQGAP2 CARMIL1 ANKDD1A CKAP2L ALDH1B1 EXOC3L2	2.46e-05	315	110	8	EFO_0005036
Disease	coronary artery disease	ZNF787 HBS1L DNAJC13 DHX58 FN1 RPS6KA1 CARMIL1 ETV1 RUNX2 ALS2CL NRXN1 NT5C2 PAN2 C5 EXOC3L2	3.75e-05	1194	110	15	EFO_0001645
Disease	obsolete_red blood cell distribution width	HBS1L DNAJC13 ANK1 CARMIL1 PABPC4 AK9 RUNX1 ARMH2 RUVBL1 PIK3R1 FECH NT5C2 HERC1 EXOC3L2 STKLD1 EIF4G3	3.97e-05	1347	110	16	EFO_0005192
Disease	immature platelet count	HBS1L IQGAP2 CARMIL1 ANKDD1A EXOC3L2	4.94e-05	106	110	5	EFO_0803544
Disease	level of Phosphatidylinositol (18:1_20:4) in blood serum	ZFHX3 LRP5L	8.22e-05	4	110	2	OBA_2045161
Disease	asthma, endometriosis	FN1 RUNX1 FAM167A C5	1.72e-04	74	110	4	EFO_0001065, MONDO_0004979
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	2.05e-04	6	110	2	EFO_0004307, EFO_0008463
Disease	mean corpuscular hemoglobin concentration	HBS1L DNAJC13 ANK1 IQGAP2 RPS6KA1 CARMIL1 PABPC4 RUNX1 PIK3R1 FECH NT5C2 MACF1 EIF4G3	2.44e-04	1105	110	13	EFO_0004528
Disease	Intellectual Disability	KDM5A YY1 CSDE1 PRR12 NRXN1 NT5C2 MACF1 ZBTB11	2.77e-04	447	110	8	C3714756
Disease	osteoarthritis (is_marker_for)	FN1 HBP1 PIK3R1	3.02e-04	35	110	3	DOID:8398 (is_marker_for)
Disease	platelet-to-lymphocyte ratio	HBS1L ANK1 IQGAP2 CARMIL1 RUNX1 BTN2A3P EXOC3L2	4.33e-04	363	110	7	EFO_0008446
Disease	Hydrocephalus	EXOC3L2 HYDIN	4.87e-04	9	110	2	C0020255
Disease	reticulocyte count	HBS1L ANK1 IQGAP2 USP9X RPS6KA1 TCIRG1 GMEB2 PIK3R1 USP32 NT5C2 HERC1 EXOC3L2	5.31e-04	1045	110	12	EFO_0007986
Disease	alpha fetoprotein measurement	SETX STXBP5L RGS12 ABRAXAS1	5.44e-04	100	110	4	EFO_0010583
Disease	FEV/FEC ratio	PABPC4 ETV1 RUNX2 ARHGEF17 YY1 TFE3 PRR12 ACAN ANKDD1A ZFHX3 HERC1 SMURF2 SDC4	6.62e-04	1228	110	13	EFO_0004713
Disease	Glioblastoma Multiforme	FN1 RUNX1 PIK3R1 STKLD1	8.06e-04	111	110	4	C1621958
Disease	apolipoprotein B measurement	HBS1L DNAJC13 ANK1 FN1 RGS12 ZFHX3 EXOC3L2 STKLD1 HYDIN	8.57e-04	663	110	9	EFO_0004615
Disease	immature platelet fraction	IQGAP2 CARMIL1 ANKDD1A EXOC3L2	8.90e-04	114	110	4	EFO_0009187
Disease	immature platelet measurement	IQGAP2 CARMIL1 ANKDD1A EXOC3L2	1.04e-03	119	110	4	EFO_0803541
Disease	creatinine measurement	DNAJC13 DGKH ST14 RGS12 PPM1G MICALL2 PIK3R1 USP32 FNIP1 ZFHX3 ZNF396	1.24e-03	995	110	11	EFO_0004518
Disease	monocyte count	HBS1L CEBPD ANK1 FN1 CARMIL1 HBP1 RUNX2 RUNX1 BTN2A3P ALDH1B1 MAPK4 EXOC3L2 NPAT	1.28e-03	1320	110	13	EFO_0005091
Disease	obesity (implicated_via_orthology)	ETV1 PLIN5 NT5C2 ZFHX3 ALDH1B1	1.29e-03	215	110	5	DOID:9970 (implicated_via_orthology)
Disease	total blood protein measurement	DNAJC13 IQGAP2 RUNX1 RGS12 MACF1 EXOC3L2 HYDIN	1.49e-03	449	110	7	EFO_0004536
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	RUNX1 FAM167A C5	1.70e-03	63	110	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	cartilage thickness measurement	RUNX2 PIK3R1	2.03e-03	18	110	2	EFO_0007873
Disease	platelet component distribution width	HBS1L IQGAP2 CARMIL1 RAPGEF3 DDHD1 ANKDD1A MACF1 HERC1 EXOC3L2	2.09e-03	755	110	9	EFO_0007984
Disease	basophil count, eosinophil count	HBS1L CEBPD RUNX1 FNIP1 EXOC3L2	2.13e-03	241	110	5	EFO_0004842, EFO_0005090
Disease	body fat percentage	DMXL2 IQCH NRXN1 PIK3R1 ACAN MACF1 ZFHX3	2.39e-03	488	110	7	EFO_0007800
Disease	brain age measurement	RUNX2 KLHL38	2.50e-03	20	110	2	EFO_0010602
Disease	myeloid white cell count	HBS1L DNAJC13 FN1 ETV1 DGKH RUNX2 ZFHX3 ALDH1B1 MAPK4 EXOC3L2	2.67e-03	937	110	10	EFO_0007988
Disease	Drugs used in diabetes use measurement	FAM185A ANK1 PABPC4 MACF1 ZFHX3	2.72e-03	255	110	5	EFO_0009924
Disease	fetal hemoglobin measurement	HBS1L PHEX	2.76e-03	21	110	2	EFO_0004576
Disease	haptoglobin measurement	ZFHX3 HYDIN	2.76e-03	21	110	2	EFO_0004640
Disease	mucocutaneous lymph node syndrome	CARMIL1 FAM167A ZFHX3	2.91e-03	76	110	3	EFO_0004246
Disease	Disproportionate short stature	RUNX2 LIFR ACAN	3.02e-03	77	110	3	C0878659
Disease	total iron binding capacity	HBS1L DNAJC13 CARMIL1	3.13e-03	78	110	3	EFO_0006334
Disease	age of onset of asthma	PABPC4 RUNX1 RUVBL1	3.24e-03	79	110	3	OBA_2001001
Disease	pyruvate measurement	HBS1L RGS12 ACAN MAPK4 HYDIN	3.36e-03	268	110	5	EFO_0010117

Protein segments in the cluster

Peptide	Gene	Start	Entry
DNLTLMVEHTDIPEA	ABRAXAS1	321	Q6UWZ7
AGLDSEPVIEMRDHE	BTN2A3P	141	Q96KV6
HPEDSVGSMEDILEE	ALS2CL	646	Q60I27
DAVVPHLAEVMQLED	EXOC3L2	281	Q2M3D2
SVHPDAIEKTIEDIM	ELMOD1	71	Q8N336
EHTHVDINEMESPLA	NT5C2	491	P49902
MEEVAHLLQDEELAP	ARMH2	101	H3BNL8
PSIVLADADMEHAVE	ALDH1B1	291	P30837
SEVENALMEHPAVVE	ACSM2A	476	Q08AH3
ALMEHPAVVETAVIS	ACSM2A	481	Q08AH3
VLDAIPLAATEHDTM	ANK1	1546	P16157
HSMPVSNEVDLDELI	SPATA5	811	Q8NB90
HIADEVEFTVVPDML	CSDE1	386	O75534
HSEAEEELINMIPAI	DMXL2	1606	Q8TDJ6
PDELTHALECAMDIF	ADCY10	356	Q96PN6
PEEHTATIEVAAMAE	GMEB2	511	Q9UKD1
EFPHMRDIVIAETLE	RCN3	196	Q96D15
VDMIEDAAHETVPIM	RASEF	636	Q8IZ41
HRDDLAVADMLDIPI	IQCH	581	Q86VS3
EAVSVMDSLVHDILD	H2BW1	101	Q7Z2G1
DHMREVLGDAVPDEI	HBS1L	86	Q9Y450
LPSEIHMSEEAIQDI	NPAT	301	Q14207
IEAHIEGMEDLQAPL	ARHGEF17	1271	Q96PE2
HEEQVLRDAPMDSIE	NUP133	706	Q8WUM0
EIDNSELLHMLESPE	PABPC4	596	Q13310
LEALPVQESVHIMEG	PAN2	46	Q504Q3
ADMEELVIPTHVRAQ	LEFTY1	46	O75610
HLEMIFGLDVVEVDP	MAGEB16	161	A2A368
HPFRIEDEIDDIVLM	MAPK4	326	P31152
LEEMAIVSDTIHPQA	FAM185A	126	Q8N0U4
PVVHEDVEMRAALQF	HERC1	2551	Q15751
EIHIPEAQEVEMASG	HPS4	371	Q9NQG7
HDVVVIDVEDDPDEM	GPR50	601	Q13585
QEEMAASEPVVHGDI	DSG4	891	Q86SJ6
GLMLLEEEHADPEAL	ECPAS	1746	Q5VYK3
EHLGIPALLDAEDMV	MICALL2	71	Q8IY33
EEVTPIAVEMTQHLA	IPO7	571	O95373
MQLILESIPVVHEED	MAPK6	241	Q16659
PFHIEDEVDDILLMD	MAPK6	331	Q16659
TDMERHINEEDTVPL	ETV1	436	P50549
LAEDQPVHGDLDLVM	MACF1	2811	O94854
LVSEDMDEPRAIALH	LRP5L	71	A4QPB2
LPVVMHTEAEDVSLR	NRXN1	731	Q9ULB1
DCDTPSVDLEMIDVH	PIK3R1	166	P27986
SVDLEMIDVHVLADA	PIK3R1	171	P27986
VIEEAGKVMDDPTVH	DGKH	631	Q86XP1
ANEIVLLEAGHEPME	NPTXR	346	O95502
VPSHAAEQLEEVMRE	KDM5A	506	P29375
DINVPDEETIFHALM	KLHL4	336	Q9C0H6
MHGIEDSEATLEVVV	ACAN	136	P16112
DLLDHVPPESVDVVM	METTL6	141	Q8TCB7
TSIEHPREAEEVMDA	POP1	761	Q99575
TADDDIFIHMPNLIE	B3GNT5	191	Q9BYG0
VHSNLEDDPEEIRME	IFT22	146	Q9H7X7
CEMLDHFDIITEEVP	HYDIN	1526	Q4G0P3
EDEPAEVSAHLQMEV	HYDIN	1541	Q4G0P3
DSMAAVPTLELCHDE	CEBPD	66	P49716
VELKMIATDPDDTHA	COL12A1	1341	Q99715
VSVVALHDDMESQPL	FN1	1791	P02751
THLLENGEDEAIVMP	FNIP1	551	Q8TF40
PEGSEVDMVEEIDHI	C5	166	P01031
LLQMALTSPEEEEHV	DHX58	106	Q96C10
LSMPVDEEVESLHLR	DNAJC13	346	O75165
EILELAEDMEIDIPH	EIF4G1	1321	Q04637
ISHLEEVSDEGIVAM	AMDHD1	281	Q96NU7
DEHMELDDLPELQAV	HBP1	51	O60381
KMASPEDVSEVLAHI	CARMIL1	96	Q5VZK9
TTGHEPEMVELVNIE	DDHD1	241	Q8NEL9
VHPLTEEAIEEMERD	FECH	166	P22830
SEEQVIMEAVAEHPI	DHX37	256	Q8IY37
EEHELPVDMETINLD	PPP1R7	61	Q15435
LDDLEDSMIGPEVVH	SDC4	66	P31431
ETLELADDMAIDIPH	EIF4G3	1301	O43432
ASDMPLECAIHFVEI	LIFR	206	P42702
EPAVLEMEDLDHLAI	OTOF	196	Q9HC10
MSVPQIHVEEVGAEE	FAM167A	1	Q96KS9
PSMASEELLLEVQHE	MIEF2	281	Q96C03
MVEVLADHPGELVRT	RUNX1	51	Q01196
TMVEIIADHPAELVR	RUNX2	101	Q13950
HEMAIEPLDDIAAVT	RTKN	451	Q9BST9
EMPVILEVSLEGSHD	RTP4	136	Q96DX8
IEEVTADHPEVVTMI	AK9	571	Q5TCS8
HSDDVPVDIMDLALS	USP9X	516	Q93008
DHLLPEAEEITMISI	USP9X	2031	Q93008
AHEELLIAVEMLSAV	IQGAP2	361	Q13576
EAALLHEEATMTIEE	PPM1G	141	O15355
SEIMVDDEELAQHPA	FTSJ3	271	Q8IY81
LHTMEREADDDSVDP	SETX	271	Q7Z333
ALDPDMIQALEDTHD	PRR12	1861	Q9ULL5
EADDMSIPISHIDDV	URB1	736	O60287
SIPISHIDDVLDMVD	URB1	741	O60287
LEMDHPIVEFLTLCE	STXBP5L	351	Q9Y2K9
HVPVLAFIMEDLEDV	ANKDD1A	136	Q495B1
PEMLQEHDLVVASLD	CKAP2L	701	Q8IYA6
PTVVGVDTHMELDEV	C10orf55	16	Q5SWW7
APVADVIAEDLVLSM	SLC49A3	51	Q6UXD7
SITLDDMELVDPDLH	SMURF2	516	Q9HAU4
PVRTHEMEEELAEAV	RAPGEF3	191	O95398
RPDVVEMHDVTAQDP	SF3B2	471	Q13435
CIADSHPEMESVDLI	ZBTB11	401	O95625
PAVVEELLSEMAAAV	ZSWIM7	6	Q19AV6
TVEDEHVAELTLMGE	RGS12	1331	O14924
PFHLGLEDILMEEEE	TFE3	516	P19532
PELVEVVVTTMELHD	STKLD1	366	Q8NE28
DDPEVVENVGMLLVH	STKLD1	606	Q8NE28
TDGSEMPAEIVELHE	YY1	11	P25490
MPAEIVELHEIEVET	YY1	16	P25490
IPQHLVEEAERVMAE	ST14	161	Q9Y5Y6
IAEIMIPHENRTSEA	PHEX	281	P78562
HEDMPVERILEAELA	RXRG	231	P48443
EAKAVDIPHMDIEAL	RPL10A	76	P62906
PGVLFVDEVHMLDIE	RUVBL1	296	Q9Y265
LVDHFLPMTEEELAA	PLIN5	161	Q00G26
HPENGEETVTMLEDV	ZNF396	116	Q96N95
PLTELEDVADVHMLV	UHRF1BP1	806	Q6BDS2
ETVHMILQELPDLEE	TBCEL	141	Q5QJ74
DDIPELHMDLSDIVE	USP32	306	Q8NFA0
DEEEAELVPSEVLMH	TCIRG1	701	Q13488
MGDPTLAEDHTIIVE	ZFHX3	1476	Q15911
ASHENPVDILIMDDD	ZNF787	21	Q6DD87
EAHIATDNVLPVMEA	KLHL38	96	Q2WGJ6
MERDILADVNHPFVV	RPS6KA1	111	Q15418