Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein phosphatase activator activity

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

6.01e-09171826GO:0072542
GeneOntologyMolecularFunctionphosphatase activator activity

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

1.84e-08201826GO:0019211
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC26A3 SLC2A9 SLC38A4 SLC44A2 ATP13A2 SLC1A2 SLC4A3 ABCA9 SLC4A1 SLCO1B7 ATP2C1 ABCA6 ABCA5 ABCC8 SLC22A10 SLC36A3 SLC41A1 ATP2B4

3.99e-0747718218GO:0022804
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT2P GGT1 GGT3P

1.46e-0561823GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT2P GGT1 GGT3P

1.46e-0561823GO:0002951
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC26A3 SLC2A9 SLC38A4 ATP13A2 SLC1A2 SLC4A3 SLC4A1 ATP2C1 ABCC8 SLC36A3 SLC41A1 ATP2B4

2.15e-0530118212GO:0022853
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT2P GGT1 GGT3P

4.03e-0581823GO:0103068
GeneOntologyMolecularFunctionATP-dependent activity

ATG7 WRN NVL NUBPL ATP13A2 ABCA9 MMAA ATP2C1 ABCA6 ABCA5 ABCC8 NAE1 KIF5C DNAH6 DHX34 ATP2B4 KIF2C

4.90e-0561418217GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

WRN NVL ATP13A2 ABCA9 MMAA ATP2C1 ABCA6 ABCA5 ABCC8 KIF5C DNAH6 DHX34 ATP2B4 KIF2C

5.52e-0544118214GO:0016887
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT2P GGT1 GGT3P

6.01e-0591823GO:0036374
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP13A2 ABCA9 ATP2C1 ABCA6 ABCA5 ABCC8 ATP2B4

6.34e-051091827GO:0042626
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC26A3 SLC2A9 SLC38A4 HCN3 SLC44A2 STING1 ATP13A2 SLC1A2 SLC4A3 ABCA9 SLC2A5 SLC4A1 SLCO1B7 MFSD14A SLC41A2 ATP2C1 MFSD14B ABCA6 ABCA5 ABCC8 SLC22A10 SCN7A SLC36A3 SLC41A1 ATP2B4

7.21e-05118018225GO:0022857
GeneOntologyMolecularFunctionABC-type transporter activity

ATP13A2 ABCA9 ABCA6 ABCA5 ABCC8

8.20e-05491825GO:0140359
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC26A3 SLC2A9 SLC38A4 SLC44A2 SLC1A2 SLC4A3 SLC4A1 SLCO1B7 SLC22A10 SLC36A3 SLC41A1

8.96e-0529618211GO:0015291
GeneOntologyMolecularFunctiontransporter activity

SLC26A3 SLC2A9 SLC38A4 HCN3 SLC44A2 STING1 ATP13A2 SLC1A2 SLC4A3 ABCA9 SLC2A5 SLC4A1 SLCO1B7 MFSD14A SLC41A2 ATP2C1 MFSD14B ABCA6 ABCA5 ABCC8 NPC1L1 SLC22A10 SCN7A SLC36A3 SLC41A1 ATP2B4

1.14e-04128918226GO:0005215
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A3 SLC4A3 SLC4A1

1.99e-04131823GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A3 SLC4A3 SLC4A1

1.99e-04131823GO:0140829
GeneOntologyMolecularFunctionprotein phosphatase regulator activity

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

3.10e-041001826GO:0019888
GeneOntologyMolecularFunctionomega peptidase activity

GGT2P GGT1 GGT3P

3.82e-04161823GO:0008242
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST1 NDST4

4.90e-0441822GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST1 NDST4

4.90e-0441822GO:0050119
GeneOntologyMolecularFunctionphosphatase regulator activity

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

5.96e-041131826GO:0019208
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGT2P GGT1 GGT3P

7.57e-04201823GO:0070003
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP13A2 ABCA9 ATP2C1 ABCA6 ABCA5 ABCC8 ATP2B4

1.26e-031781827GO:0015399
GeneOntologyBiologicalProcessprotein dephosphorylation

FAM220A LRRIQ4 EYA1 PPM1J PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C LRRD1

1.89e-0525618311GO:0006470
GeneOntologyBiologicalProcessglutathione biosynthetic process

SLC1A2 GGT2P GGT1 GGT3P

2.60e-05201834GO:0006750
GeneOntologyBiologicalProcesscysteine biosynthetic process

GGT2P GGT1 GGT3P

3.72e-0581833GO:0019344
GeneOntologyBiologicalProcessnonribosomal peptide biosynthetic process

SLC1A2 GGT2P GGT1 GGT3P

3.87e-05221834GO:0019184
GeneOntologyBiologicalProcesspeptide modification

GGT2P GGT1 GGT3P

7.88e-05101833GO:0031179
GeneOntologyBiologicalProcessleukotriene D4 biosynthetic process

GGT2P GGT1 GGT3P

7.88e-05101833GO:1901750
GeneOntologyBiologicalProcessglutathione catabolic process

GGT2P GGT1 GGT3P

1.08e-04111833GO:0006751
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

3.91e-07181845GO:0000159
GeneOntologyCellularComponentphosphatase complex

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

8.69e-06551846GO:1903293
GeneOntologyCellularComponentprotein serine/threonine phosphatase complex

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP4R3C

8.69e-06551846GO:0008287
MousePhenodecreased cysteine level

GGT2P GGT1 GGT3P ALDH1L2

6.35e-0781394MP:0030623
MousePhenoabnormal cysteine level

GGT2P GGT1 GGT3P ALDH1L2

6.24e-06131394MP:0030621
MousePhenodecreased glutathione level

GGT2P GGT1 GGT3P ALDH1L2

6.24e-06131394MP:0012604
MousePhenoabnormal glutathione level

GGT2P GGT1 GGT3P ALDH1L2

6.24e-06131394MP:0012603
MousePhenoabnormal circulating glutathione level

GGT2P GGT1 GGT3P

9.48e-0651393MP:0030652
MousePhenoincreased circulating glutathione level

GGT2P GGT1 GGT3P

9.48e-0651393MP:0030653
MousePhenoglutathionuria

GGT2P GGT1 GGT3P

9.48e-0651393MP:0013730
MousePhenoincreased glutathione level

GGT2P GGT1 GGT3P

9.48e-0651393MP:0012606
MousePhenodecreased circulating cysteine level

GGT2P GGT1 GGT3P

3.27e-0571393MP:0030626
MousePhenoepididymis hypoplasia

GGT2P GGT1 GGT3P

5.19e-0581393MP:0004932
MousePhenonervous

GGT2P GGT1 GGT3P

7.74e-0591393MP:0008912
MousePhenofailure of copulatory plug deposition

GGT2P GGT1 GGT3P

1.10e-04101393MP:0030983
MousePhenoseminal vesicle hypoplasia

GGT2P GGT1 GGT3P

1.10e-04101393MP:0005148
MousePhenoovary hypoplasia

GGT2P GGT1 GGT3P

1.10e-04101393MP:0005158
MousePhenoabnormal circulating cysteine level

GGT2P GGT1 GGT3P

1.50e-04111393MP:0030624
MousePhenoabsent tertiary ovarian follicles

GGT2P GGT1 GGT3P

1.50e-04111393MP:0011130
MousePhenoabnormal urine amino acid level

GGT2P GGT1 GGT3P AGTR1 HSD11B2

2.94e-04591395MP:0011468
MousePhenopriapism

GGT2P GGT1 GGT3P

3.23e-04141393MP:0003415
MousePhenodecreased circulating follicle stimulating hormone level

AR GGT2P GGT1 GGT3P

3.44e-04341394MP:0002790
DomainPP2A_B56

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

8.32e-1151825IPR002554
DomainB56

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

8.32e-1151825PF01603
DomainARM-type_fold

GBF1 NBEAL1 HSF2BP ARMC9 HEATR1 TRRAP LYST PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E CSE1L TELO2 ARID2 MROH2B EIF4G2 MROH7 UNC79 TBCD

1.33e-1033918220IPR016024
DomainARM-like

HSF2BP ARMC9 HEATR1 TRRAP PPP2R5A PPP2R5C PPP2R5E CSE1L TELO2 ARID2 MROH2B MROH7 TBCD

2.56e-0627018213IPR011989
Domain-

HSF2BP ARMC9 HEATR1 TRRAP PPP2R5C PPP2R5E CSE1L TELO2 MROH2B MROH7 TBCD

1.18e-05222182111.25.10.10
DomainSUGAR_TRANSPORT_1

SLC2A9 SLC2A5 MFSD14A MFSD14B

7.96e-05241824PS00216
Domain-

PDC PDCL

9.44e-05218221.10.168.10
DomainPhosducin_N_dom

PDC PDCL

9.44e-0521822IPR023196
DomainABC_A

ABCA9 ABCA6 ABCA5

1.88e-04121823IPR026082
DomainSugar_transporter_CS

SLC2A9 SLC2A5 MFSD14A MFSD14B

2.53e-04321824IPR005829
DomainRasGAP_C

IQGAP2 IQGAP3

2.82e-0431822IPR000593
Domain-

SLC41A2 SLC41A1

2.82e-04318221.10.357.20
DomainAnion_exchange_CS

SLC4A3 SLC4A1

2.82e-0431822IPR018241
DomainMgtE

SLC41A2 SLC41A1

2.82e-0431822PF01769
DomainRasGAP_C

IQGAP2 IQGAP3

2.82e-0431822PF03836
DomainSLC41_membr_dom

SLC41A2 SLC41A1

2.82e-0431822IPR006667
DomainLRR_1

LRRC32 LINGO2 LRRIQ4 SKP2 LINGO1 CD14 SLIT3 FLRT3 LRRD1

3.05e-042191829PF00560
DomainAAA

NVL ABCA9 MMAA ABCA6 ABCA5 ABCC8 DNAH6

5.32e-041441827SM00382
DomainAAA+_ATPase

NVL ABCA9 MMAA ABCA6 ABCA5 ABCC8 DNAH6

5.32e-041441827IPR003593
DomainPhosducin

PDC PDCL

5.59e-0441822IPR001200
DomainPhosducin

PDC PDCL

5.59e-0441822PF02114
DomainHeparan_SO4_deacetylase

NDST1 NDST4

5.59e-0441822IPR021930
DomainHSNSD

NDST1 NDST4

5.59e-0441822PF12062
DomainPhosducin_thioredoxin-like_dom

PDC PDCL

5.59e-0441822IPR024253
DomainMFS

SLC2A9 SLC2A5 SLCO1B7 MFSD14A MFSD14B SLC22A10

6.63e-041081826PS50850
DomainCation_ATPase_N

ATP13A2 ATP2C1 ATP2B4

6.67e-04181823SM00831
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP2C1 ATP2B4

7.86e-04191823IPR004014
DomainLRR

LRRC32 LINGO2 LRRIQ4 LINGO1 CD14 SLIT3 FLRT3 LRRD1

8.11e-042011828PS51450
DomainSterol-sensing

NPC1L1 PTCH2

9.26e-0451822PF12349
DomainTet-R_TetA/multi-R_MdtG

MFSD14A MFSD14B

9.26e-0451822IPR001958
DomainAnion_exchange

SLC4A3 SLC4A1

9.26e-0451822IPR001717
DomainIQ

RASGRF1 IQGAP2 LRRIQ4 SCN7A IQGAP3

1.17e-03811825SM00015
DomainABC_tran

ABCA9 ABCA6 ABCA5 ABCC8

1.21e-03481824PF00005
DomainABC_TRANSPORTER_2

ABCA9 ABCA6 ABCA5 ABCC8

1.21e-03481824PS50893
DomainABC_TRANSPORTER_1

ABCA9 ABCA6 ABCA5 ABCC8

1.31e-03491824PS00211
DomainPH_BEACH

NBEAL1 LYST

1.38e-0361822PF14844
DomainLeu-rich_rpt

LRRC32 LINGO2 LRRIQ4 SKP2 LINGO1 CD14 SLIT3 FLRT3 LRRD1

1.39e-032711829IPR001611
DomainABC_transporter-like

ABCA9 ABCA6 ABCA5 ABCC8

1.42e-03501824IPR003439
DomainLRR_8

LRRC32 LINGO2 LRRIQ4 LINGO1 SLIT3 FLRT3 LRRD1

1.46e-031711827PF13855
DomainLRRNT

LRRC32 LINGO2 SLIT3 FLRT3

1.76e-03531824PF01462
DomainLRR_TYP

LRRC32 LINGO2 LRRIQ4 LINGO1 SLIT3 FLRT3 LRRD1

1.78e-031771827SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC32 LINGO2 LRRIQ4 LINGO1 SLIT3 FLRT3 LRRD1

1.78e-031771827IPR003591
DomainIQ_motif_EF-hand-BS

RASGRF1 IQGAP2 LRRIQ4 SCN7A IQGAP3

1.87e-03901825IPR000048
DomainGGT_peptidase

GGT1 GGT3P

1.92e-0371822IPR000101
DomainG_glu_transpept

GGT1 GGT3P

1.92e-0371822PF01019
DomainANION_EXCHANGER_2

SLC4A3 SLC4A1

1.92e-0371822PS00220
DomainG_GLU_TRANSPEPTIDASE

GGT1 GGT3P

1.92e-0371822PS00462
DomainANION_EXCHANGER_1

SLC4A3 SLC4A1

1.92e-0371822PS00219
DomainMFS_dom

SLC2A9 SLC2A5 SLCO1B7 MFSD14A MFSD14B SLC22A10

2.02e-031341826IPR020846
DomainIQ

RASGRF1 IQGAP2 LRRIQ4 IQCJ IQGAP3

2.16e-03931825PS50096
DomainPH-BEACH_dom

NBEAL1 LYST

2.54e-0381822IPR023362
Domain-

NBEAL1 LYST

2.54e-03818222.30.29.40
DomainPH_BEACH

NBEAL1 LYST

2.54e-0381822PS51783
DomainLRRNT

LRRC32 LINGO2 LINGO1 SLIT3 FLRT3

2.72e-03981825IPR000372
DomainLRRNT

LRRC32 LINGO2 LINGO1 SLIT3 FLRT3

2.72e-03981825SM00013
Domain-

SLC4A3 SLC4A1

3.25e-03918223.40.1100.10
DomainBEACH

NBEAL1 LYST

3.25e-0391822PS50197
DomainBeach

NBEAL1 LYST

3.25e-0391822PF02138
Domain-

NBEAL1 LYST

3.25e-03918221.10.1540.10
DomainBeach

NBEAL1 LYST

3.25e-0391822SM01026
DomainBand3_cytoplasmic_dom

SLC4A3 SLC4A1

3.25e-0391822IPR013769
DomainBand_3_cyto

SLC4A3 SLC4A1

3.25e-0391822PF07565
DomainBEACH_dom

NBEAL1 LYST

3.25e-0391822IPR000409
DomainPtc/Disp

NPC1L1 PTCH2

3.25e-0391822IPR003392
DomainPatched

NPC1L1 PTCH2

3.25e-0391822PF02460
DomainThiF_NAD_FAD-bd

ATG7 NAE1

4.04e-03101822IPR000594
DomainThiF

ATG7 NAE1

4.04e-03101822PF00899
DomainPTrfase/Anion_transptr

SLC4A3 SLC4A1

4.04e-03101822IPR016152
DomainHCO3_transpt_euk

SLC4A3 SLC4A1

4.04e-03101822IPR003020
DomainCUE

N4BP2 ASCC2

4.04e-03101822IPR003892
DomainHCO3_cotransp

SLC4A3 SLC4A1

4.04e-03101822PF00955
DomainHCO3_transpt_C

SLC4A3 SLC4A1

4.04e-03101822IPR011531
DomainCUE

N4BP2 ASCC2

4.04e-03101822PS51140
Domain-

LRRC32 LINGO2 LRRIQ4 SKP2 LINGO1 CD14 SLIT3 FLRT3 LRRD1

4.33e-0332118293.80.10.10
DomainHEAT_REPEAT

HEATR1 MROH2B MROH7 TBCD

4.85e-03701824PS50077
DomainL_dom-like

LRRC32 LINGO2 LRRIQ4 SKP2 LINGO1 CD14 SLIT3 FLRT3 LRRD1

4.97e-033281829IPR032675
DomainMFS_sugar_transport-like

SLC2A9 SLC2A5 SLC22A10

5.13e-03361823IPR005828
DomainATPase_P-typ_P_site

ATP13A2 ATP2C1 ATP2B4

5.13e-03361823IPR018303
DomainP_typ_ATPase

ATP13A2 ATP2C1 ATP2B4

5.13e-03361823IPR001757
DomainSugar_tr

SLC2A9 SLC2A5 SLC22A10

5.13e-03361823PF00083
DomainATPASE_E1_E2

ATP13A2 ATP2C1 ATP2B4

5.13e-03361823PS00154
DomainATPase_P-typ_transduc_dom_A

ATP13A2 ATP2C1 ATP2B4

5.54e-03371823IPR008250
DomainE1-E2_ATPase

ATP13A2 ATP2C1 ATP2B4

5.54e-03371823PF00122
DomainLipid-bd_serum_glycop_C

BPIFB3 BPIFA2

5.85e-03121822IPR001124
Domain-

ATG7 AASS NAE1 HSD11B2 HSD17B4 SDR16C5

6.31e-0316918263.40.50.720
DomainSSD

NPC1L1 PTCH2

6.86e-03131822IPR000731
DomainSSD

NPC1L1 PTCH2

6.86e-03131822PS50156
DomainLBP_BPI_CETP

BPIFB3 BPIFA2

6.86e-03131822PF01273
DomainBPI/LBP/Plunc

BPIFB3 BPIFA2

6.86e-03131822IPR032942
DomainBactericidal_perm-incr_a/b_dom

BPIFB3 BPIFA2

6.86e-03131822IPR017943
DomainLipid-bd_serum_glycop_N

BPIFB3 BPIFA2

6.86e-03131822IPR017942
DomainNAD(P)-bd_dom

ATG7 AASS NAE1 HSD11B2 HSD17B4 SDR16C5

7.05e-031731826IPR016040
DomainRasGAP

IQGAP2 IQGAP3

7.96e-03141822SM00323
DomainSugar/inositol_transpt

SLC2A9 SLC2A5

7.96e-03141822IPR003663
DomainNPIP

NPIPB8 NPIPB6

7.96e-03141822IPR009443
DomainRasGAP_CS

IQGAP2 IQGAP3

7.96e-03141822IPR023152
DomainP-loop_NTPase

NDST1 WRN NDST4 NVL NUBPL ABCA9 DRG1 MMAA ABCA6 ABCA5 N4BP2 ABCC8 KIF5C DNAH6 DHX34 KIF2C

8.89e-0384818216IPR027417
DomainRasGAP

IQGAP2 IQGAP3

9.12e-03151822PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP2 IQGAP3

9.12e-03151822PS00509
DomainRAS_GTPASE_ACTIV_2

IQGAP2 IQGAP3

9.12e-03151822PS50018
PathwayREACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.77e-07151435M27407
PathwayKEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

4.00e-07161435M47870
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.62e-07171435MM15096
PathwayREACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.62e-07171435M27083
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.62e-07171435M919
PathwayREACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

7.71e-07181435MM14759
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.04e-06191435M47525
PathwayWP_GLYCOGEN_METABOLISM

PHKB PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.04e-06341436MM15985
PathwayKEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.37e-06201435M47876
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.79e-06211435M5876
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.79e-06211435MM14996
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.29e-06221435M47919
PathwayWP_GLYCOGEN_SYNTHESIS_AND_DEGRADATION

PHKB PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.83e-06401436M39595
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.38e-05311435M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.38e-05311435MM15154
PathwayREACTOME_RAF_ACTIVATION

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.20e-05341435M27556
PathwayWP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.20e-05341435M42555
PathwayREACTOME_SIGNALING_BY_WNT_IN_CANCER

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.20e-05341435M27405
PathwayREACTOME_RAF_ACTIVATION

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.54e-05351435MM15271
PathwayREACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

6.30e-05421435MM15274
PathwayREACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

7.07e-05431435M27560
PathwayREACTOME_PLATELET_HOMEOSTASIS

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E ATP2B4

1.20e-04761436MM15051
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC2A9 SLC38A4 SLC44A2 SLC1A2 SLC4A3 SLC4A1 SLCO1B7 SLC41A2 SLC41A1

1.56e-0423814310MM15076
PathwayREACTOME_DRUG_ADME

PON1 GGT2P GGT1 GGT3P SLCO1B7 UGT3A2 HSD11B2

2.07e-041191437MM15692
PathwayREACTOME_PLATELET_HOMEOSTASIS

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E ATP2B4

2.37e-04861436M916
PathwayREACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING

GGT2P GGT1 GGT3P

5.20e-04161433MM14680
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E KIF2C

5.35e-041001436MM14561
PathwayWP_IL6_SIGNALING_PATHWAY

AR PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.35e-041001436MM15826
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC26A3 SLC2A9 SLC38A4 SLC44A2 ATP13A2 SLC1A2 SLC4A3 ABCA9 SLC4A1 SLCO1B7 SLC41A2 ATP2C1 ABCA6 ABCA5 SLC41A1 UNC79 ATP2B4

5.36e-0468114317MM14985
PathwayREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.44e-04661435MM14990
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA9 ABCA6 ABCA5

6.26e-04171433MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA9 ABCA6 ABCA5

7.46e-04181433M524
PathwayREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

9.20e-04741435M17386
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E KIF2C

9.28e-041111436M27673
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC2A9 SLC38A4 SLC44A2 SLC1A2 SLC4A3 SLC4A1 SLC41A2 SLC41A1

9.90e-042491439M5988
PathwayREACTOME_INTESTINAL_ABSORPTION

SLC2A5 NPC1L1

1.00e-0351432M27833
PathwayKEGG_ABC_TRANSPORTERS

ABCA9 ABCA6 ABCA5 ABCC8

1.01e-03441434M11911
PathwayKEGG_OOCYTE_MEIOSIS

AR PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.02e-031131436M16817
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E KIF2C

1.22e-031171436MM15387
PathwayREACTOME_RHO_GTPASE_EFFECTORS

IQGAP2 AR PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E IQGAP3 KIF2C

1.23e-032571439MM14755
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.24e-03791435MM14754
PathwayWP_EICOSANOID_SYNTHESIS

GGT2P GGT1 GGT3P

1.37e-03221433MM15961
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.71e-03851435M27079
PathwayREACTOME_FATTY_ACID_METABOLISM

ACADVL PON1 GGT2P GGT1 GGT3P MMAA HSD17B4

1.74e-031701437MM15573
PathwayWP_OXYLIPINS_PATHWAYS

GGT2P GGT1 GGT3P

1.77e-03241433MM17249
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E KIF2C

1.86e-031271436M27181
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

GGT2P GGT1 GGT3P

2.00e-03251433MM14858
PathwayPID_MYC_PATHWAY

SKP2 TRRAP PPP2R5A

2.00e-03251433M139
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E KIF2C

2.01e-031291436MM14894
Pubmed

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

4.38e-12518858812429
Pubmed

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

4.38e-125188515095873
Pubmed

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

9.11e-11718858703017
Pubmed

Identification of a new family of protein phosphatase 2A regulatory subunits.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

9.11e-11718857592815
Pubmed

De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.42e-109188530595372
Pubmed

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.42e-109188523345399
Pubmed

Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

3.36e-0912188515380617
Pubmed

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

3.36e-0912188516541024
Pubmed

The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits.

PPP2R5A PPP2R5B PPP2R5C PPP2R5E

4.12e-09518848694763
Pubmed

PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.44e-0913188521072166
Pubmed

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

8.42e-091418859400615
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

8.42e-0914188516048649
Pubmed

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

8.42e-091418859013886
Pubmed

Regulation of HIV-1 transcription by protein phosphatase 1.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.57e-0817188517266553
Pubmed

[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.57e-0817188521351466
Pubmed

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.

ATG7 GGT2P GGT1 GGT3P

2.86e-087188436685533
Pubmed

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

3.54e-0818188523287597
Pubmed

Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

4.78e-0819188516541025
Pubmed

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis.

AR PLEKHA5 ATP2B4

1.55e-073188333355366
Pubmed

Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth.

PPP2R5B PPP2R5C PPP2R5D

1.55e-073188325972378
Pubmed

Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.

GGT2P GGT1 GGT3P

1.55e-07318832573352
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZBTB33 FAT3 SIRPB1 GPR108 NUBPL TRRAP SLC4A1 DRG1 VANGL2 EDEM3 METTL13 IGF2BP2 PPP2R5A ATP2C1 PPP2R5E MCTP1 TELO2 ARID2 PDCL DHX34 TCTN2 WDR72

1.91e-0711161882231753913
Pubmed

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.62e-0726188511531413
Pubmed

Defining the membrane proteome of NK cells.

DPP4 GBF1 GPAA1 NVL DGKA HEATR1 IFI16 DRG1 INTS5 ATP2C1 NOP14 CSE1L LNPEP EIF4G2 PLEKHA5 DHX34 RPL4 ATP2B4 RPL6 ADPGK GAA KIF2C

4.12e-0711681882219946888
Pubmed

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

DPP4 SIRPB1 GGT2P GGT1 GGT3P

4.68e-0729188522424930
Pubmed

Two types of abnormal genes for plasminogen in families with a predisposition for thrombosis.

PLGLA PLG PLGLB1

6.19e-07418831986355
Pubmed

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.

EYA1 GGT2P GGT1 GGT3P VANGL2 AGTR1 EIF4G2

8.92e-0795188720843830
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGT2P GGT1 GGT3P

1.54e-065188323615310
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGT2P GGT1 GGT3P

1.54e-065188311003618
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGT2P GGT1 GGT3P

1.54e-065188310392451
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGT2P GGT1 GGT3P

1.54e-065188319850887
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA9 ABCA6 ABCA5

1.54e-065188312532264
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-065188312810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-06518838755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-065188311089562
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGT2P GGT1 GGT3P

1.54e-065188326977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGT2P GGT1 GGT3P

1.54e-065188312225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGT2P GGT1 GGT3P

1.54e-06518837775425
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGT2P GGT1 GGT3P

1.54e-06518839139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGT2P GGT1 GGT3P

1.54e-065188320622017
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-06518839546365
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGT2P GGT1 GGT3P

1.54e-06518837485380
Pubmed

Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.

GGT2P GGT1 GGT3P

1.54e-065188310751614
Pubmed

Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.

GGT2P GGT1 GGT3P

1.54e-06518837523374
Pubmed

Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.

GGT2P GGT1 GGT3P

1.54e-065188324698228
Pubmed

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.

GGT2P GGT1 GGT3P

1.54e-065188310474818
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGT2P GGT1 GGT3P

1.54e-065188318063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGT2P GGT1 GGT3P

1.54e-065188310940879
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-065188311095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGT2P GGT1 GGT3P

1.54e-06518837641802
Pubmed

The mouse skin carcinogenesis model.

GGT2P GGT1 GGT3P

1.54e-06518839627710
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGT2P GGT1 GGT3P

1.54e-065188312453183
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGT2P GGT1 GGT3P

1.54e-06518832891746
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGT2P GGT1 GGT3P

1.54e-065188328660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

1.54e-065188312468440
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGT2P GGT1 GGT3P

1.54e-06518838566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGT2P GGT1 GGT3P

1.54e-065188330591459
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGT2P GGT1 GGT3P

1.54e-065188311795900
Pubmed

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.

GGT2P GGT1 GGT3P

1.54e-065188325132819
Pubmed

Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.

GGT2P GGT1 GGT3P

1.54e-065188319760322
Pubmed

Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.

GGT2P GGT1 GGT3P

3.07e-066188314634009
Pubmed

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

GGT2P GGT1 GGT3P

3.07e-06618838101000
Pubmed

Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.

GGT2P GGT1 GGT3P

3.07e-06618838104871
Pubmed

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

GGT2P GGT1 GGT3P

3.07e-066188311463821
Pubmed

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.

GGT2P GGT1 GGT3P

3.07e-066188325326709
Pubmed

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

GGT2P GGT1 GGT3P

3.07e-066188312163373
Pubmed

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

GGT2P GGT1 GGT3P

3.07e-066188322242126
Pubmed

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

GGT2P GGT1 GGT3P

3.07e-066188317363454
Pubmed

Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.

GGT2P GGT1 GGT3P

3.07e-06618838663190
Pubmed

Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota.

ATG7 STING1 EPG5

3.07e-066188334520306
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TCAF1 MAGED1 HEATR1 DRG1 TAOK2 YIF1A INTS5 ATP2C1 PPP2R5D PPP2R5E CSE1L TELO2 EIF4G2 PLG ATP2B4 IQGAP3 GAA TBCD

4.07e-069421881831073040
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

IQGAP2 WRN NVL HEATR1 TRRAP DRG1 IGF2BP2 NOP14 CSE1L UTP15 ARID2 MED23 RPL4 IQGAP3 RPL6 KIF2C

4.22e-067591881635915203
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

GBF1 HEATR1 TRRAP TELO2 CPSF1 IQGAP3 TBCD

4.29e-06120188727320910
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

EYA1 PPM1J PHKB HSPA12A IGF2BP2 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E NOP14 CSE1L TELO2 LNPEP PRIM2 CPSF1 HSD17B4 PFDN6 ATP2B4

4.68e-0610491881927880917
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

5.01e-0646188518782753
Pubmed

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

GGT2P GGT1 GGT3P

5.35e-067188332284594
Pubmed

Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits.

PPP2R5B PPP2R5D PPP2R5E

5.35e-067188335415460
Pubmed

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.

GGT2P GGT1 GGT3P

5.35e-067188327775020
Pubmed

Defective epidermal growth factor gene expression in mice with polycystic kidney disease.

GGT2P GGT1 GGT3P

5.35e-06718831968405
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MAGED1 ACADVL NVL HEATR1 TTC1 DRG1 VANGL2 HSPA12A PPP2R5D NOP14 TELO2 UTP15 LNPEP N4BP2 NAE1 EIF4G2 ASCC2 PLEKHA5 PDCL PFDN6 RPL4 ATP2B4 RPL6

6.14e-0614871882333957083
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

GBF1 WRN PHKB MROH7 RPL4 IQGAP3 RPL6 ADPGK

1.54e-05202188833005030
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA9 ABCA6 ABCA5

1.81e-0510188311435397
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

GGT2P GGT1 GGT3P

1.81e-0510188323863468
Pubmed

The tumor suppressor PP2A Abeta regulates the RalA GTPase.

PPP2R5A PPP2R5C PPP2R5D PPP2R5E

2.64e-0532188417540176
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

MAGED1 GPAA1 SLC44A2 RXFP3 PPM1J SLC4A3 OPRL1 MFSD14A YIF1A ATP2C1 CHPT1 ABCC8 AGTR1 TCTN2

2.90e-056971881428298427
Pubmed

Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone.

AR PLEKHA5

2.91e-052188219013130
Pubmed

The effect of a sertoli cell-selective knockout of the androgen receptor on testicular gene expression in prepubertal mice.

AR PLEKHA5

2.91e-052188216166195
Pubmed

Gamma glutamyl transferase activity is independently associated with oxidative stress rather than SYNTAX score.

GGT2P GGT1

2.91e-052188225180444
Pubmed

Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells.

AR PLEKHA5

2.91e-052188215107499
Pubmed

Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein.

IFI16 AR

2.91e-052188216494870
Pubmed

LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease.

LINGO2 LINGO1

2.91e-052188220369371
Pubmed

Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study.

GGT2P GGT1

2.91e-052188225280803
Pubmed

Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.

AR PLEKHA5

2.91e-052188221152390
Pubmed

Effects of novel chalcone derivatives on α-glucosidase, dipeptidyl peptidase-4, and adipocyte differentiation in vitro.

DPP4 GAA

2.91e-052188221699755
Pubmed

Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes.

AR PLEKHA5

2.91e-052188216973730
Pubmed

Identification of testosterone-/androgen receptor-regulated genes in mouse Sertoli cells.

AR PLEKHA5

2.91e-052188222002438
Pubmed

Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor.

AR PLEKHA5

2.91e-052188215919750
Pubmed

Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.

IQGAP2 IQGAP3

2.91e-052188229073199
Pubmed

Skp2 regulates androgen receptor through ubiquitin-mediated degradation independent of Akt/mTOR pathways in prostate cancer.

SKP2 AR

2.91e-052188224347472
Pubmed

B56beta, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching.

PPP2R5B PPP2R5E

2.91e-052188218385213
InteractionCCNG2 interactions

SKP2 PPP2R5B PPP2R5C PPP2R5D PPP2R5E

2.89e-07171785int:CCNG2
InteractionNPTN interactions

GBF1 NBEAL1 FAM210A HEATR1 STING1 HSPA12A INTS5 CSE1L TELO2 AGTR1 ATP2B4 TBCD DOP1B

1.21e-0627817813int:NPTN
InteractionGPR182 interactions

TCAF1 GBF1 GPAA1 FAM210A HEATR1 EDEM3 METTL13 INTS5 ATP2C1 CSE1L CHPT1 TELO2 MED23 ADPGK TBCD DOP1B

2.99e-0645517816int:GPR182
InteractionC1orf21 interactions

DPP4 STING1 PPP2R5A PPP2R5B PPP2R5E

1.33e-05351785int:C1orf21
InteractionFAM43A interactions

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

1.53e-05361785int:FAM43A
InteractionPRR14 interactions

STING1 PPP2R5A PPP2R5C PPP2R5D PPP2R5E

2.29e-05391785int:PRR14
InteractionKLHL14 interactions

TTC1 PPP2R5A PPP2R5B PPP2R5D PPP2R5E IQGAP3

2.56e-05661786int:KLHL14
InteractionPPP2CB interactions

ATG7 TTC1 IFI16 INTS5 PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PLEKHA5 PFDN6

2.66e-0526717811int:PPP2CB
InteractionMGARP interactions

GBF1 FAM210A HEATR1 HSPA12A INTS5 ATP2C1 TELO2 LNPEP TBCD DOP1B

2.92e-0522217810int:MGARP
InteractionDHFR2 interactions

MAGED1 TTC1 DRG1 LNPEP N4BP2 HSD17B4 RPL4 RPL6 GAA TCTN2 KIF2C

5.46e-0528917811int:DHFR2
InteractionTMEM9B interactions

ITPRIPL2 HEATR1 STING1 VANGL2 YIF1A INTS5 ATP2C1

5.85e-051111787int:TMEM9B
InteractionWNT3A interactions

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

7.07e-05491785int:WNT3A
InteractionGPR45 interactions

GBF1 HEATR1 NUBPL EDEM3 HSPA12A METTL13 INTS5 ATP2C1 CSE1L TELO2 AASS

7.62e-0530017811int:GPR45
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E

4.31e-08151265696
GeneFamilySolute carriers

SLC26A3 SLC2A9 SLC38A4 SLC44A2 SLC1A2 SLC4A3 SLC2A5 SLC4A1 SLCO1B7 SLC41A2 SLC22A10 SLC36A3 SLC41A1

3.89e-0639512613752
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT2P GGT1 GGT3P

8.98e-05131263564
GeneFamilyATP binding cassette subfamily A

ABCA9 ABCA6 ABCA5

1.14e-04141263805
GeneFamilyOlfactory receptors, family 51

OR51A4 OR51A2 OR51A7 OR51H1

2.46e-04441264164
GeneFamilyCD molecules|V-set domain containing|C1-set domain containing|Signal regulatory proteins

SIRPB2 SIRPB1

4.75e-0451262747
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 LYST

1.68e-03912621230
GeneFamilyATPases Ca2+ transporting

ATP2C1 ATP2B4

1.68e-03912621209
GeneFamilyUbiquitin like modifier activating enzymes

ATG7 NAE1

2.09e-03101262100
GeneFamilyMaestro heat like repeat containing

MROH2B MROH7

2.54e-03111262636
GeneFamilyBPI fold containing

BPIFB3 BPIFA2

5.42e-03161262456
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

DPP4 FTCD SERPINA12 SLCO1B7 SLC41A2 AASS SLC22A10 UGT3A2 PLG

9.16e-061901869MM1311
CoexpressionGSE27786_LSK_VS_CD8_TCELL_UP

MORC1 NDST1 TCAF1 ITPRIPL2 NFAM1 TELO2 CC2D2A HSD17B4 IQGAP3

1.33e-051991869M4749
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NDST1 CYP3A7 SLC2A9 SLC38A4 FTCD SLC1A2 CHPT1 AASS PLG

1.28e-071921879e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A NUBPL PPM1J SLC2A5 SLC41A2 PLEKHA5 TTC22 PLGLB1

4.18e-0716118781011094c54381d52566e24c92f89f2efc2aa3eea
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CPED1 ABCA9 NOP14 ABCA6 SLIT3 SCN7A PLEKHA5

1.58e-06192187811088878043a6ff95ba1970361256a82e434b80a
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 TTC39C PON1 FTCD SERPINA12 CHPT1 PLG

3.57e-061511877e243b6c76e59035f10519a86399b598dd2123f87
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 TTC39C PON1 FTCD SERPINA12 CHPT1 PLG

3.57e-061511877cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 HSF2BP PPM1J NFAM1 LYST TTC22 PDZD2

5.01e-061591877709b57f992a29878cc899d760d144d36cb5cb280
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DPP4 CLEC9A NUBPL PPM1J SLC4A3 SLC41A2 PLEKHA5

5.90e-061631877a09449a502627aa369db600dba5bda93de7ce5c0
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 HSF2BP SLC1A2 PPP2R5A MCTP1 SLC41A1 SDR16C5

6.15e-061641877b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 HSF2BP SLC1A2 PPP2R5A MCTP1 SLC41A1 SDR16C5

6.15e-0616418773aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

MORC1 HIVEP1 SLC44A2 HES2 NPIPB6 N4BP2 KIF2C

6.15e-06164187706db4cc064f0765c481ce880207823872c27bfa9
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 CLEC9A NUBPL PPM1J SLC4A3 SLC41A2 PLEKHA5

6.15e-061641877ed888b55d9c685096fd785878fcb264f4fee88d6
ToppCelldroplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A RASGRF1 EYA1 VANGL2 SLC41A2 UNC79 ADPGK

8.72e-0617318771b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCelldroplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC9A RASGRF1 EYA1 VANGL2 SLC41A2 UNC79 ADPGK

8.72e-061731877c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

PLGLA SLC38A4 PON1 FTCD SLC22A10 PLG PLGLB1

9.05e-061741877452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLGLA PON1 FTCD SLC1A2 SLC22A10 PLG PLGLB1

9.39e-0617518777f74961436f88c0e380819095e6104489914d765
ToppCellCOVID-mDC1|COVID / Condition, Cell_class and T cell subcluster

CLEC9A RASGRF1 HCN3 ARMC9 PPM1J SLC4A3 NPIPB6

9.39e-061751877b9280444016e21c28131a61df65cc5c56d402412
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLGLA PON1 FTCD SLC1A2 SLC22A10 PLG PLGLB1

9.39e-061751877bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellCOVID-mDC1-|COVID / Condition, Cell_class and T cell subcluster

CLEC9A RASGRF1 HCN3 ARMC9 PPM1J SLC4A3 NPIPB6

9.39e-06175187783a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

DPP4 SIRPB1 ATP13A2 SLC4A3 AR SLC41A2 MCTP1

9.75e-061761877ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 HSF2BP CPED1 LINGO1 ABCA6 AGTR1 SLIT3

9.75e-061761877b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 HSF2BP CPED1 LINGO1 ABCA6 AGTR1 SLIT3

9.75e-06176187766c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD PLEKHA5 PLG UNC79 PDZD2 WDR72

1.13e-0518018771363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD IGF2BP2 PLG UNC79 PDZD2 WDR72

1.17e-0518118779542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL19A1 SGCZ MCTP1 SLIT3 DNAH6 ATP2B4 PDZD2

1.17e-0518118779de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD IGF2BP2 PLG UNC79 PDZD2 WDR72

1.17e-0518118778f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EYA1 ABCA9 IGF2BP2 ABCA6 ABCA5 SCN7A ATP2B4

1.55e-051891877e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLA-05._Cytoplasmic_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SLC26A3 MUC16 SLC41A2 LINGO1 FLRT3 RPL4 RPL6

1.66e-051911877d825e55278dce666c332cc060d1255659e07e568
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GBF1 HEATR1 LYST LNPEP ARID2 ZBTB40 DOP1B

1.66e-0519118779454f642c3621370fa23640b631301346b300950
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC1A2 ABCA9 ABCA6 AASS AGTR1 SLIT3 SCN7A

1.77e-051931877261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

DPP4 CLEC9A NUBPL PPM1J NPIPB6 PLEKHA5 RPL4

1.83e-051941877d21461682fa755f588afe073abb6a777f339c4cc
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

FAT3 ABCA9 IGF2BP2 ABCA6 SLIT3 SCN7A PLEKHA5

1.89e-051951877603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

BPIFB3 IGF2BP2 ABCC8 MROH7 UGT3A2

2.20e-058018753413ac5e1c1e59eab6a83b889b870a8db4efccb9
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

ZBTB33 GBF1 HEATR1 SLC2A5 RMI1 ATP2C1 CSE1L

2.23e-052001877118321ac443feb42aee171baccfc4610f00a8822
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 EYA1 IGF2BP2 ABCA5 ALDH1L2 SLIT3 PLEKHA5

2.23e-052001877682960e28542a3d6c119047cd0131941932cfdea
ToppCellSepsis-URO-Lymphocyte-T/NK-CD4+_Tcm|URO / Disease, condition lineage and cell class

ST6GALNAC1 DPP4 NBEAL1 TTC39C DGKA KIF5C RPL6

2.23e-0520018774689fd4c6e7f078d7e91783a1646dd85c03cba77
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 TTC39C FTCD SERPINA12 CHPT1 PLG

4.80e-051541876a5289000597068ee8d559f89bce7bce31f35dd57
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLEC9A PPM1J SLC4A3 VANGL2 SLC41A2 HSD11B2

5.34e-05157187619c0599a669803c4db1f174de1ce755e562a50a3
ToppCell368C-Myeloid-Dendritic-cDC1|368C / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A NUBPL PPM1J SLC2A5 OPRL1 SLC41A2

5.53e-051581876c276a259e20ee704e2d04baf693e8d677f96f654
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT3 ABCA9 ABCA6 MROH2B SLIT3 SCN7A

5.53e-051581876e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC26A3 FAT3 NDST4 SERPINA12 ABCA5 HEPHL1

6.36e-051621876bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CLEC9A NUBPL PPM1J SLC2A5 TTC22 PLGLB1

6.58e-051631876299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

SLC38A4 CPED1 SLC1A2 ABCA9 AR ABCA6

6.80e-0516418763d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OXER1 HIVEP1 KMT2B PPM1J SYT15B TTC22

7.28e-051661876c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCellControl-Epithelial_airway-Club_cells-Airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST6GALNAC1 EYA1 SLC1A2 SGCZ KIF5C SDR16C5

7.77e-051681876ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCellControl-Epithelial_airway-Club_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST6GALNAC1 EYA1 SLC1A2 SGCZ KIF5C SDR16C5

7.77e-051681876e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

MORC1 HIVEP1 SLC44A2 HES2 NPIPB6 KIF2C

7.77e-0516818764bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SKP2 NFAM1 IL1RL2 ATP13A2 ABCA9 CD14

8.03e-051691876454b92b9b67299a64278c010db033ca5b9d217a0
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SGCZ NPIPB6 ABCC8 NPC1L1 KIF5C UNC79

8.03e-05169187696a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

LRRC32 SIRPB2 STING1 SLIT3 SCN7A PTCH2

8.03e-051691876e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 CPED1 SGCZ HSPA12A AGTR1 SLIT3

8.30e-0517018765570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

DPP4 GBF1 SLC44A2 PPM1J ATP13A2 DOP1B

8.57e-051711876f3bf5805823d5733b58742172e7668725ce82931
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF1 ITPRIPL2 SRMS ALS2 NFAM1 CD14

8.57e-051711876d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

PPM1J SLC4A3 AR SLC41A2 NPIPB8 ABCA6

8.57e-05171187672c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CLEC9A FAM220A NFAM1 LYST SLC4A1

9.14e-051731876513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD PLG UNC79 PDZD2 WDR72

9.14e-0517318768888434641ea554a9b62c436e87920378eef29cd
ToppCellIIF-Lymphocyte-T_NK-CD4_TEM|IIF / Disease, Lineage and Cell Type

DPP4 NBEAL1 PPP2R5C FLRT3 RPL4 RPL6

9.73e-0517518760e7cde3bd638ab85abe915d40c432123f92af4fc
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 HCN3 ARMC9 NUBPL UTP15 KIF5C

1.04e-041771876e1e45956887371b1c18f1eb479dd930031497520
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

GBF1 WRN IL1RL2 PRIM2 OR8G5 MED23

1.04e-041771876eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 FAT3 PON1 EYA1 PHKB ASCC2

1.04e-041771876e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 FAT3 PON1 EYA1 PHKB ASCC2

1.04e-041771876b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PPP2R5A ABCA5 HSD11B2 PDZD2 WDR72

1.07e-04178187651d2188406f04329311b2efd1108fc36617a860e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

STING1 NFAM1 IL1RL2 SLC2A5 CD14 IQGAP3

1.10e-0417918765122fc794509492afde4af8b1b76d51e3070ef05
ToppCellURO-Lymphocyte-T_NK-CD4_TCM|URO / Disease, Lineage and Cell Type

ST6GALNAC1 DPP4 NBEAL1 TTC39C KIF5C RPL6

1.10e-041791876cdf972acf23c7a22c99a336ee0f9cc51e0fa6f67
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP3A7 FAT3 CPED1 SLC2A5 ABCA6 SLIT3

1.14e-0418018769b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 IQGAP2 TTC39C DGKA PPP2R5C ATP2B4

1.14e-041801876d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A3 FAT3 FTCD SGCZ LINGO1 PDZD2

1.17e-041811876c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 COL19A1 FTCD PLG PDZD2 WDR72

1.24e-04183187684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD PLEKHA5 PLG PDZD2 WDR72

1.24e-041831876facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBF1 FUOM HSPA12A PRIM2 TTC22 HSD17B4

1.28e-041841876af6522586d012e91241f3e06c60f9d1881e95646
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL19A1 STING1 MCTP1 SLIT3 DNAH6 ATP2B4

1.28e-041841876ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC2A9 FTCD GGT1 PLG PDZD2 WDR72

1.28e-041841876dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

FAM210A TAOK2 RMI1 METTL13 NAE1 TCTN2

1.36e-041861876403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 FTCD PLEKHA5 PLG PDZD2 WDR72

1.36e-0418618765784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

DPP4 SLC2A9 FTCD PLG PDZD2 WDR72

1.40e-041871876acd305475f3609800af0d7bc68d83ef41228080b
ToppCellControl-Lymphocyte-T_NK-CD4_TCM|Control / Disease, Lineage and Cell Type

ST6GALNAC1 NBEAL1 TTC39C DGKA RPL4 RPL6

1.40e-0418718761de80f40f753b31aed1fac9f3ff8a2ee6c755eec
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPP4 RASGRF1 GGT2P HSD17B4 SDR16C5 PDZD2

1.40e-0418718765df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LINGO2 LYST ABCA9 IGF2BP2 ABCA6 ABCA5

1.40e-04187187677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EYA1 ABCA9 IGF2BP2 ABCA6 ABCA5 SCN7A

1.40e-041871876f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC26A3 SLC2A9 FTCD LINGO1 PLG WDR72

1.40e-041871876738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.44e-0418818765df5a0890e17d19f55770525345a656253696887
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

CLEC9A LRRC32 STING1 MCTP1 SCN7A PTCH2

1.44e-041881876c90669b51e1902fe7726555290c91c92a911df83
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.44e-0418818769e923b0d79495ee1a3a097741a877f25d439eda3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.44e-04188187614dbc985abc2012c9f53deb243d465e4175f419f
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NDST1 SIRPB2 SIRPB1 OPRL1 KIF5C GAA

1.48e-041891876bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.48e-041891876e9fe8d17f4b7cca9bbf3655047e27b2fec5060c1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.48e-0418918767ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.48e-041891876389ccb68acb82893709f256315111470cf4beed3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.48e-04189187658465b9407fbce91cca8f199950d6e0054c38fbc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 SLC1A2 ABCA9 ABCA6 AGTR1 SLIT3

1.52e-0419018762306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC9A SIRPB2 IFI16 CPED1 SLC2A5 CD14

1.52e-041901876d4f954e0748898df69e1710df558564db703dd61
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 SLC1A2 ABCA9 ABCA6 AGTR1 SLIT3

1.52e-0419018761f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 SLC1A2 ABCA9 ABCA6 AGTR1 SLIT3

1.57e-041911876a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA9 AR NOP14 ABCA6 SCN7A PLEKHA5

1.57e-0419118767d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 SLC1A2 ABCA9 ABCA6 AGTR1 SLIT3

1.61e-0419218769093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 SLC1A2 ABCA9 ABCA6 AGTR1 SLIT3

1.61e-0419218769ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CLEC9A SLC2A9 STING1 SLC2A5 CD14 GAA

1.61e-0419218764037b4c4fbb40541b8c424c36d3871a57891b8dd
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

SLC2A9 IQGAP2 ATG7 SIRPB2 MCTP1 CD14

1.66e-04193187612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

DPP4 IQGAP2 TTC39C PPP2R5C KIF5C ATP2B4

1.66e-041931876af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 RASGRF1 SLC4A3 HSPA12A LINGO1 ATP2B4

1.66e-0419318768689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 RASGRF1 SLC4A3 HSPA12A LINGO1 ATP2B4

1.66e-041931876be28070c049e7cb68bcd54f582226eb2f5e4bc1c
Diseasestromal cell-derived factor 1 measurement

DPP4 ABCA6 ABCA5

7.30e-0671773EFO_0020756
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT2P GGT1 GGT3P

7.30e-0671773DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT2P GGT1 GGT3P

1.16e-0581773DOID:0050741 (biomarker_via_orthology)
DiseaseMalformations of Cortical Development

NDST1 KIF5C TBCD

7.36e-05141773C1955869
DiseaseCortical Dysplasia

NDST1 KIF5C TBCD

7.36e-05141773C0431380
Diseasecorpus callosum posterior volume measurement

ATP13A2 ENO4 IQCJ PTCH2

2.71e-04521774EFO_0010298
Diseasecorpus callosum volume measurement

TTC39C ATP13A2 ENO4 PPP2R5E IQCJ

3.49e-041001775EFO_0010299
Diseaseneuroimaging measurement, brain volume measurement

DPP4 FAT3 CPED1 ATP13A2 NPIPB8 IQCJ ASCC2 SLC41A1

3.50e-042861778EFO_0004346, EFO_0006930
DiseaseDistal Renal Tubular Acidosis

SLC4A1 WDR72

3.54e-0451772C1704380
Diseasegamma-aminobutyric acid receptor-associated protein-like 1 measurement

ATG7 DHX34

3.54e-0451772EFO_0801613
DiseaseParkinson's disease (implicated_via_orthology)

ATG7 ATP13A2 OPRL1 YIF1A EIF4G2 PTCH2

3.83e-041571776DOID:14330 (implicated_via_orthology)
DiseaseMicronuclei, Chromosome-Defective

PON1 PPP2R5C PPP2R5E

4.98e-04261773C1449861
DiseaseMicronuclei, Genotoxicant-Induced

PON1 PPP2R5C PPP2R5E

4.98e-04261773C1449862
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2C1 ATP2B4

5.28e-0461772DOID:0050429 (implicated_via_orthology)
Diseasecorpus callosum mid-anterior volume measurement

TTC39C SLC1A2 WDR72

5.58e-04271773EFO_0010297
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

ALS2 ATP13A2 EPG5

7.65e-04301773DOID:332 (implicated_via_orthology)
DiseaseChromosomal Instability

PPP2R5C PPP2R5E

9.78e-0481772C1257806
DiseaseLiver carcinoma

KMT2B IQGAP2 ATG7 SKP2 AR PPP4R3C ARID2 SLC22A10 IQGAP3 KIF2C

1.03e-0350717710C2239176
Diseasesignal-regulatory protein beta-1 measurement

SIRPB2 SIRPB1

1.25e-0391772EFO_0802069
DiseaseGout

SLC2A9 CD14

1.25e-0391772C0018099
DiseaseMeckel-Gruber syndrome

CC2D2A TCTN2

1.56e-03101772cv:C0265215
Diseaseleptin measurement, sex interaction measurement

ABCA9 SLIT3

1.56e-03101772EFO_0005000, EFO_0008343
Disease2-aminobutyrate measurement

LINGO2 EPG5

1.56e-03101772EFO_0020017
DiseaseIntellectual Disability

NDST1 ARMC9 TRRAP SLC1A2 PPP2R5D AASS ZBTB40 MED23 TBCD

1.58e-034471779C3714756
Diseasebody weight

HIVEP1 RASGRF1 NBEAL1 SLC44A2 LINGO2 TTC1 IZUMO3 SGCZ IGF2BP2 LINGO1 ABCC8 SLIT3 PDCL SDR16C5 UNC79 ATP2B4 PDZD2

1.60e-03126117717EFO_0004338
Diseasethalamus volume

FAT3 CD14 PLEKHA5 OR2A2

1.74e-03851774EFO_0006935
Diseasesmoking status measurement

MORC1 DPP4 GBF1 FAT3 LINGO2 IZUMO3 RMI1 ATP2C1 MCTP1 LINGO1 CLYBL LNPEP IQCJ CC2D2A UNC79 WDR72

1.74e-03116017716EFO_0006527
DiseaseDiabetic Retinopathy

PON1 AGTR1

1.90e-03111772C0011884
Diseasecysteine-glutathione disulfide measurement

NFAM1 GGT1

1.90e-03111772EFO_0021001
DiseaseProteinuria

DPP4 MUC16 AGTR1

2.20e-03431773C0033687
DiseaseParkinson Disease, Secondary Vascular

PON1 ATP13A2

2.27e-03121772C0751414
DiseaseAtherosclerotic Parkinsonism

PON1 ATP13A2

2.27e-03121772C0751415
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

NDST1 SLIT3

2.27e-03121772DOID:3827 (implicated_via_orthology)
DiseaseSecondary Parkinson Disease

PON1 ATP13A2

2.27e-03121772C0030569
DiseaseSpina Bifida

PON1 VANGL2

2.27e-03121772C0080178
DiseaseStatus Dysraphicus

PON1 VANGL2

2.27e-03121772C0038219
DiseaseRachischisis

PON1 VANGL2

2.27e-03121772C0266508
DiseaseHbA1c measurement

CYP3A7 SLC4A1 OPRL1 IGF2BP2 LINGO1 NPIPB6 IQCJ ABCC8 ASCC2 ATP2B4 TBCD

2.64e-0367517711EFO_0004541
DiseaseVitiligo, response to rhododendrol

COL19A1 PPP2R5C

2.67e-03131772EFO_0004208, EFO_0010824
DiseaseGastrointestinal Stromal Sarcoma

NDST1 PTCH2 CC2D2A

2.83e-03471773C3179349
DiseaseMale sterility

PON1 AR ENO4

3.01e-03481773C0917731
DiseaseMale infertility

PON1 AR ENO4

3.01e-03481773C0021364
DiseaseSubfertility, Male

PON1 AR ENO4

3.01e-03481773C0848676
Diseasemyocardial infarction (is_implicated_in)

WRN PON1 CD14 AGTR1

3.03e-03991774DOID:5844 (is_implicated_in)
Diseasebiliary atresia (is_marker_for)

GGT1 CD14

3.11e-03141772DOID:13608 (is_marker_for)
DiseaseBell's palsy

MAGED1 EYA1 EIF4G2 CC2D2A

3.37e-031021774EFO_0007167
DiseaseGastrointestinal Stromal Tumors

NDST1 PTCH2 CC2D2A

3.38e-03501773C0238198
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

MORC1 HIVEP1 LINGO2 IZUMO3 RMI1 HSPA12A MCTP1 LINGO1 CLYBL IQCJ PLEKHA5 UNC79

3.39e-0380117712EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseMeckel-Gruber syndrome

CC2D2A TCTN2

3.57e-03151772C0265215
Diseaseanemia (implicated_via_orthology)

SLC4A3 SLC4A1

3.57e-03151772DOID:2355 (implicated_via_orthology)
Diseaseuric acid measurement

PDC SLC2A9 FAT3 AR IGF2BP2 PPP2R5B ABCA6 SLC22A10 SLC41A1 WDR72

3.92e-0361017710EFO_0004761
Disease5-oxoproline measurement

GPAA1 RMI1

4.06e-03161772EFO_0010988
Diseasesarcoidosis (is_implicated_in)

CD14 AGTR1

4.06e-03161772DOID:11335 (is_implicated_in)
DiseaseC-X-C motif chemokine 6 measurement

VANGL2 TELO2

4.06e-03161772EFO_0008059
Diseaseestradiol measurement

CYP3A7 ARMC9 AR UGT3A2

4.41e-031101774EFO_0004697
Diseaseserum IgG glycosylation measurement

SLC26A3 COL19A1 WRN LINGO2 SGCZ MCTP1 ALDH1L2 SLIT3 DHX34

4.48e-035231779EFO_0005193
DiseaseGlycogen storage disease

PHKB GAA

4.59e-03171772cv:C0017919
DiseaseHerpes Zoster

LRRC32 IZUMO3

4.59e-03171772EFO_0006510
Diseasefree cholesterol to total lipids in large HDL percentage

PON1 ABCA6 PLG

4.66e-03561773EFO_0022279
DiseaseMeckel syndrome type 1

CC2D2A TCTN2

5.14e-03181772C3714506
Diseaseantihyperlipidemic drug use measurement

OPRL1 ABCA6 NPC1L1 WDR72

5.16e-031151774EFO_0803367
Diseaserenovascular hypertension (biomarker_via_orthology)

AGTR1 EIF4G2

5.72e-03191772DOID:1591 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VVLLLLLFLKSGQGE

PLGLB1

6

Q02325
EPVTNGLKDGIVFLL

VANGL2

466

Q9ULK5
GIAVLGNPKILLLDE

ABCA5

626

Q8WWZ7
LEILGSIINGFALPL

PPP2R5B

256

Q15173
LLEILGSIINGFALP

PPP2R5E

241

Q16537
ALKGVNVVPFLELIG

FAM210A

156

Q96ND0
KFCAEGIPLLGILVQ

EPG5

1036

Q9HCE0
GVLFSLLGAQPLLVV

SLC4A3

751

P48751
VLLKLLPGFGVQLSL

BPIFB3

101

P59826
VLSGVKLLQALGLSP

ADPGK

86

Q9BRR6
KLLVGALVALGLSEP

C6orf136

291

Q5SQH8
LLNILVIIKTLGIGF

CPED1

881

A4D0V7
VQGILFALLGAQPLL

SLC4A1

446

P02730
LNKQPDIALLGFLGV

ALS2

1511

Q96Q42
LTFGIAILGDPQVLL

ABCA9

626

Q8IUA7
LPIGLGLTKNILGFL

AGTR1

191

P30556
VSLELGGKSPLIIFN

ALDH1L2

691

Q3SY69
ILDLCVLFGKGNSPL

ASCC2

161

Q9H1I8
DGLQITLGLLALQPF

FAM220A

236

Q7Z4H9
IGTKIGLFLQVAPLS

FLRT3

11

Q9NZU0
RKLTFGITILGDPQI

ABCA6

621

Q8N139
GFLVAKQDLVISLLP

AASS

541

Q9UDR5
DPKIITLLLANAGVF

ARID2

196

Q68CP9
LEILGSIINGFALPL

PPP2R5D

301

Q14738
EILGSIINGFALPLK

PPP2R5C

226

Q13362
VNFFGALELTKGLLP

HSD11B2

191

P80365
LLKFEIQAGLLGRPI

DET1

496

Q7L5Y6
FLPKVLDLIVNGISI

ATP2B4

496

P23634
PELGQLTFLGLVGII

ATP2C1

531

P98194
TLKVGPQVGLFLDAV

CLYBL

186

Q8N0X4
GDFLGPQQIKDLLLA

MROH7

686

Q68CQ1
IGGLNVLFPLLEQIS

NBEAL1

871

Q6ZS30
LPLKTGLLIADYLGI

SDR16C5

281

Q8N3Y7
LPGGRKVILLYLDQL

IQCJ

121

Q1A5X6
QFKALGLVTPAGVLL

NVL

606

O15381
LLLQKLQLGGPEGDL

MORC1

926

Q86VD1
LSGPVLALILNILKG

GGT3P

281

A6NGU5
TERVLQGLLGPIFKN

MUC16

12416

Q8WXI7
GLTEKSELQLPLFLV

OR8G5

51

Q8NG78
ILGLTKKPELQGIIF

OR13G1

11

Q8NGZ3
FLPKLISLDLTGNLI

LRRD1

301

A4D1F6
ADFLGKVAIPLLSIQ

MCTP1

701

Q6DN14
LGNNQIFPKTGLLII

MAGEA4

191

P43358
DTPKLGLLLVILGVI

MAGED1

556

Q9Y5V3
AKIQLLDLPGIIEGA

DRG1

111

Q9Y295
PAVGFLLLVLGLKAL

GPAA1

376

O43292
QLLGVKFIAELGVPL

ZBTB33

106

Q86T24
LKILGLTGNEFLSFP

LRRIQ4

351

A6NIV6
QSLSQLKGLILPLLG

HES2

31

Q9Y543
LKGLILPLLGRENSN

HES2

36

Q9Y543
LIQPQLGELSGEKLL

ARMC9

606

Q7Z3E5
LQKLLLPSLQAFIVG

DOP1B

136

Q9Y3R5
LLAFFPGLQVLKGDI

EDEM3

351

Q9BZQ6
GELPLVKEVLLVALG

CPSF1

841

Q10570
DGSNVVFKLLGPVLV

PFDN6

51

O15212
VFKLLGPVLVKQELG

PFDN6

56

O15212
LPTLLIYKGGELISN

PDC

186

P20941
NSEVKLFLLIGIPGL

OR51A7

6

Q8NH64
LLGNGTILAVIKVEP

OR51H1

41

Q8NH63
EILDVNGIPIKGLTF

PDZD2

636

O15018
IPALAKVLLYGLGIV

EYA1

506

Q99502
SPQKLDNLIIIIIGF

NPIPB8

71

E9PQR5
IESLGIKGFISQLLP

MED23

576

Q9ULK4
IGQLSLIPKFLTEVL

MED23

1221

Q9ULK4
VFNLLKDGPEIGLRL

DGKA

406

P23743
GGELFLTVLLNPISI

NDST1

511

P52848
KLLPGSAIQALVGLA

KCT2

16

Q8NC54
LINNIFELAGLGKVP

LNPEP

731

Q9UIQ6
RLKLVPLGVFTGLSN

LINGO2

116

Q7L985
LKLIPLGVFTGLSNL

LINGO1

131

Q96FE5
LLEQKVLIGALSPGL

MMAA

391

Q8IVH4
KVLLGLLGAAALVTI

DPP4

6

P27487
VLQGLLSSKVVGPLL

KMT2B

1416

Q9UMN6
LLLFSIIPVDGLKNQ

AR

811

P10275
IPQDVGLTILKGAVL

HSPA12A

506

O43301
GLTILKGAVLFGLDP

HSPA12A

511

O43301
QLFGDRKLPLAGQVL

IGF2BP2

21

Q9Y6M1
GGELFLTILLNPISI

NDST4

501

Q9H3R1
ILGNGTILFIIKTEP

OR51A2

41

Q8NGJ7
ILGNGTILFIIKTEP

OR51A4

41

Q8NGJ6
GNLIVLPVGITFFKE

HCN3

106

Q9P1Z3
PGLDVLIYLKITGLL

NOP14

541

P78316
GIIKAFRNIPGITLL

RPL4

216

P36578
LEILEGKGLSFLFPL

EIF4G2

716

P78344
VVLLLLLFLKSGQGE

PLGLA

6

Q15195
LPAFSKIGGILANEL

IQGAP3

186

Q86VI3
LIQGVKGLLSFLSAP

MFSD14A

76

Q96MC6
APILALEFVLGLVGN

OXER1

96

Q8TDS5
ITLLGFQVGPALAIL

OR2A2

11

Q6IF42
FETLIQLGVLPALKI

PPP4R3C

356

Q6ZMV5
GGLKNINLIIILTFI

LRRC32

621

Q14392
LLGPKNFSGILDLDL

NPC1L1

426

Q9UHC9
TNLPGILVLGLAKAQ

NPC1L1

1246

Q9UHC9
LFLKGIGLTLEQALQ

PRIM2

311

P49643
IVVPESLGFGLLKNL

IL1RL2

451

Q9HB29
DGLGIPQLLEAVLKL

FUOM

51

A2VDF0
FKLLLLGLVTLNFVG

ATP13A2

1116

Q9NQ11
LNLSFAGLEQVPKGL

CD14

281

P08571
EPILLKQIFISGGRL

DNAH6

3136

Q9C0G6
LIQGPVGLDQRFSLK

ATG7

161

O95352
AGPIIGQIINLKASL

BPIFA2

136

Q96DR5
VPNISILGLSLFKLA

CC2D2A

1001

Q9P2K1
ALPLLGDIGALLKNF

COL19A1

681

Q14993
QGEPGLLETKALGLL

FRMPD1

891

Q5SYB0
LAEIPGLSINFAKVL

HSD17B4

391

P51659
LGKNLLLTLTVFGVI

SLC1A2

41

P43004
LLFKLLATVSQGLPG

FAT3

21

Q8TDW7
KLNIEGELPAAVGLL

LYST

3426

Q99698
ILQFNLLGVPLVGAD

GAA

631

P10253
ILGPVIKAEVGDTLL

HEPHL1

456

Q6MZM0
GAKAALVILFIIGLL

HEPHL1

1111

Q6MZM0
GLGKLIKIFEDIPTL

IFI16

61

Q16666
ILKGFDPLLNLVLDG

LSM7

36

Q9UK45
VLDGLGLPTLQVDIF

ENO4

76

A6NNW6
KGIQFLQEKGLLTIP

GBF1

716

Q92538
IGVFTGQLLGLPELL

SLC2A9

211

Q9NRM0
GQLLGLPELLGKEST

SLC2A9

216

Q9NRM0
LFLLGKLLIVGSVGI

SLC44A2

601

Q8IWA5
LLLGTVAGIFPDKVL

HEATR1

1306

Q9H583
TQIPLKLRFGGLLLT

CYP3A7

471

P24462
VKSILTPEGVFILNL

METTL13

601

Q8N6R0
IKTPEIANLALLGFG

FBXW2

361

Q9UKT8
QLALLKLVLGRGLYP

DHX34

796

Q14147
LFPGLAIKIQRSNGL

KIF2C

11

Q99661
SPQKLDNLIIIIIGF

NPIPB6

71

E9PJ23
QGVKGLLSFLSAPLI

MFSD14C

86

Q5VZR4
QGVKGLLSFLSAPLI

MFSD14B

86

Q5SR56
GSQLVGLVPLKALLD

FTCD

266

O95954
LSGPVLALILNILKG

GGT2P

281

P36268
AILLGILLKREGPNF

PHKB

741

Q93100
KLAQTLGLEVLGDIP

NUBPL

261

Q8TB37
NALPALLIYKGGELI

PDCL

231

Q13371
PKFIEDVGSLLGNLI

IZUMO3

26

Q5VZ72
GGFPLLKVAVLLLLS

ITPRIPL2

46

Q3MIP1
LPLGLKVTIVGLYLA

OPRL1

46

P41146
KVLLGFVLPLGIIIL

RXFP3

271

Q9NSD7
LDTILQLLGDLKPGQ

HSF2BP

211

O75031
SPVVDKKFLLLQGLV

UTP15

456

Q8TED0
NILLGLKGLAPAEIS

STING1

131

Q86WV6
EILPNGLAFISSGLK

PON1

56

P27169
LFTVGKLGPFLLNAV

TCAF1

276

Q9Y4C2
LNLLLKDLGEIGGII

KIF5C

551

O60282
GNISFRLGVLLLKPE

RMI1

171

Q9H9A7
IIGGLIVFLLPETKN

SLC22A10

506

Q63ZE4
LFKLGIAPQIQDLLG

IQGAP2

156

Q13576
KNLRGALGVVPQLFI

SLC2A5

156

P22732
PQKLLLFGFTGLLSV

NFAM1

161

Q8NET5
KAIVLVLFGALLGLS

PTCH2

686

Q9Y6C5
LLKGALLFITIALIG

GPR108

336

Q9NPR9
LQLLGFLKPELLGSE

PPM1J

306

Q5JR12
SLLILGNRGFKNVPL

ST6GALNAC1

421

Q9NSC7
NILLSEPGLVKLGDF

TAOK2

156

Q9UL54
QPGFILLRETLLGKV

TELO2

146

Q9Y4R8
FILVPALLGLKGNLE

SLC41A1

136

Q8IVJ1
VFILVPALLGLKGNL

SLC41A2

196

Q96JW4
DILGEKFGIGLPILF

WRN

971

Q14191
KGIRLEGISEFLLPL

SGCZ

76

Q96LD1
LAIGFLLAPLQKSVL

SLC26A3

426

P40879
KTNFLLGVLALPAVA

SLCO1B7

326

G3V0H7
SPAGLKAVLQLLVEG

INTS5

681

Q6P9B9
SVGIILPLSLLKNLG

SLC38A4

206

Q969I6
LQKGRLFPGLEELLT

SRMS

181

Q9H3Y6
EAPENFKIGSLLGLL

MROH2B

921

Q7Z745
VVLLLLLFLKSGQGE

PLG

6

P00747
FGAGLLKEAQLPVIE

PLG

711

P00747
IPIITGGKALDLAAL

RASGRF1

761

Q13972
AIKNAGLLVGPVSLL

SLC36A3

66

Q495N2
GLAIFLAVLLTVKGL

SERPINA12

6

Q8IW75
IAQLKLVVKALPGGL

ABCC8

1456

Q09428
LVVKALPGGLDAIIT

ABCC8

1461

Q09428
LKELGAFGLQVPSEL

ACADVL

136

P49748
EILGSIINGFALPLK

PPP2R5A

251

Q15172
GLLTASIFLGVKLLQ

CLEC9A

46

Q6UXN8
EIKLKILPVLGFLGG

CHPT1

221

Q8WUD6
VKGLFDGLVSLQLLL

SLIT3

371

O75094
LLGPKLLLVVGVSAI

SIRPB1

376

O00241
LGEIPTLKTLQVFGI

SKP2

356

Q13309
QVFGIVPDGTLQLLK

SKP2

366

Q13309
TGLLVVFAPVVLGLK

SIRPB2

286

Q5JXA9
EILLTNLFKALTLPG

CSE1L

551

P55060
ALGIQKRFSPEVLGL

YIF1A

156

O95070
KQLASGLLLVTGPLV

RPL6

166

Q02878
LLGQVLFPLKNETLV

SYT15B

296

X6R8R1
ILKLQGPISLGISLN

WDR72

821

Q3MJ13
IIPLNQGLKSLVGVL

SCN7A

216

Q01118
ALPGFLLKGRLQQVL

TBCD

781

Q9BTW9
GFLLPGVLLSEAAKI

UGT3A2

11

Q3SY77
GLQPFGSLFLLITQK

nan

86

Q6AWC8
NLLKIINLLGFPGDR

TTC39C

236

Q8N584
KEEGILGSILLPSFQ

PLEKHA5

206

Q9HAU0
LKDLGNLVLRPFGLS

TTC1

251

Q99614
LKNLVLPGIGSFTII

NAE1

46

Q13564
ELGATLPELQLLRGK

TTC22

426

Q5TAA0
PQLLTCLVGSEGKLL

TRRAP

3236

Q9Y4A5
KPILFGENVLSGCLL

TCTN2

476

Q96GX1
KLGLVLQPDAGGLFL

HIVEP1

461

P15822
KGLLALEGELTPILV

PPIP5K1

591

Q6PFW1
LQAVKTTFPNLGLLL

ZBTB40

426

Q9NUA8
AGLLLDTIKRPALQG

UNC79

1111

Q9P2D8
LSGPVLALILNILKG

GGT1

281

P19440
GPFSLGLNLKEIISQ

N4BP2

1151

Q86UW6