Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	extracellular matrix	ADAMTSL1 FCGBP IGFALS VASN ICAM1 PAPLN CHADL ADAMTS14 MUC2 SSPOP	8.37e-06	656	56	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTSL1 FCGBP IGFALS VASN ICAM1 PAPLN CHADL ADAMTS14 MUC2 SSPOP	8.59e-06	658	56	10	GO:0030312
Domain	TSP_1	ADAMTSL1 PAPLN ADAMTS14 C9 SSPOP	1.36e-06	63	57	5	PF00090
Domain	TSP1	ADAMTSL1 PAPLN ADAMTS14 C9 SSPOP	1.59e-06	65	57	5	SM00209
Domain	TSP1_rpt	ADAMTSL1 PAPLN ADAMTS14 C9 SSPOP	1.59e-06	65	57	5	IPR000884
Domain	TSP1	ADAMTSL1 PAPLN ADAMTS14 C9 SSPOP	1.59e-06	65	57	5	PS50092
Domain	VWC	DGCR2 FCGBP MUC2 SSPOP	5.33e-06	38	57	4	SM00214
Domain	TIL	FCGBP MUC2 SSPOP	5.81e-06	12	57	3	PF01826
Domain	C8	FCGBP MUC2 SSPOP	5.81e-06	12	57	3	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP MUC2 SSPOP	7.54e-06	13	57	3	IPR014853
Domain	C8	FCGBP MUC2 SSPOP	7.54e-06	13	57	3	SM00832
Domain	Cys-rich_flank_reg_C	SLITRK2 IGFALS VASN PKD1 CHADL	7.98e-06	90	57	5	IPR000483
Domain	LRRCT	SLITRK2 IGFALS VASN PKD1 CHADL	7.98e-06	90	57	5	SM00082
Domain	VWF_dom	DGCR2 FCGBP MUC2 SSPOP	8.00e-06	42	57	4	IPR001007
Domain	TIL_dom	FCGBP MUC2 SSPOP	9.58e-06	14	57	3	IPR002919
Domain	LRRNT	SLITRK2 IGFALS VASN PKD1 CHADL	1.21e-05	98	57	5	IPR000372
Domain	LRRNT	SLITRK2 IGFALS VASN PKD1 CHADL	1.21e-05	98	57	5	SM00013
Domain	LDLRA_1	DGCR2 PKD1 C9 SSPOP	1.37e-05	48	57	4	PS01209
Domain	VWD	FCGBP MUC2 SSPOP	1.47e-05	16	57	3	SM00216
Domain	VWF_type-D	FCGBP MUC2 SSPOP	1.47e-05	16	57	3	IPR001846
Domain	VWFD	FCGBP MUC2 SSPOP	1.47e-05	16	57	3	PS51233
Domain	VWD	FCGBP MUC2 SSPOP	1.47e-05	16	57	3	PF00094
Domain	LDLRA_2	DGCR2 PKD1 C9 SSPOP	1.49e-05	49	57	4	PS50068
Domain	LRRNT	SLITRK2 IGFALS VASN PKD1	2.04e-05	53	57	4	PF01462
Domain	VWC_out	FCGBP MUC2 SSPOP	2.52e-05	19	57	3	SM00215
Domain	PLAC	ADAMTSL1 PAPLN ADAMTS14	2.52e-05	19	57	3	PS50900
Domain	PLAC	ADAMTSL1 PAPLN ADAMTS14	2.52e-05	19	57	3	IPR010909
Domain	LRR	NLRP12 SLITRK2 IGFALS VASN PKD1 CHADL	3.31e-05	201	57	6	PS51450
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 PAPLN ADAMTS14	5.21e-05	24	57	3	IPR013273
Domain	BRK	CHD9 CHD7	1.36e-04	6	57	2	SM00592
Domain	BRK_domain	CHD9 CHD7	1.36e-04	6	57	2	IPR006576
Domain	BRK	CHD9 CHD7	1.36e-04	6	57	2	PF07533
Domain	Leu-rich_rpt	NLRP12 SLITRK2 IGFALS VASN PKD1 CHADL	1.72e-04	271	57	6	IPR001611
Domain	LRR_8	SLITRK2 IGFALS VASN PKD1 CHADL	1.73e-04	171	57	5	PF13855
Domain	VWFC_1	DGCR2 MUC2 SSPOP	1.79e-04	36	57	3	PS01208
Domain	Leu-rich_rpt_typical-subtyp	SLITRK2 IGFALS VASN PKD1 CHADL	2.03e-04	177	57	5	IPR003591
Domain	LRR_TYP	SLITRK2 IGFALS VASN PKD1 CHADL	2.03e-04	177	57	5	SM00369
Domain	VWFC_2	DGCR2 MUC2 SSPOP	2.11e-04	38	57	3	PS50184
Domain	LDLR_class-A_CS	DGCR2 C9 SSPOP	2.46e-04	40	57	3	IPR023415
Domain	Ldl_recept_a	DGCR2 C9 SSPOP	3.49e-04	45	57	3	PF00057
Domain	-	DGCR2 C9 SSPOP	3.73e-04	46	57	3	4.10.400.10
Domain	IG_FLMN	FLNB FLNC	4.05e-04	10	57	2	SM00557
Domain	-	NLRP12 SLITRK2 IGFALS VASN PKD1 CHADL	4.27e-04	321	57	6	3.80.10.10
Domain	LDrepeatLR_classA_rpt	DGCR2 C9 SSPOP	4.49e-04	49	57	3	IPR002172
Domain	LDLa	DGCR2 C9 SSPOP	4.49e-04	49	57	3	SM00192
Domain	L_dom-like	NLRP12 SLITRK2 IGFALS VASN PKD1 CHADL	4.79e-04	328	57	6	IPR032675
Domain	Filamin	FLNB FLNC	4.94e-04	11	57	2	PF00630
Domain	FILAMIN_REPEAT	FLNB FLNC	4.94e-04	11	57	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB FLNC	4.94e-04	11	57	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC	4.94e-04	11	57	2	IPR017868
Domain	PLAC	ADAMTSL1 PAPLN	8.13e-04	14	57	2	PF08686
Domain	CTCK_1	MUC2 SSPOP	1.36e-03	18	57	2	PS01185
Domain	ADAM_spacer1	PAPLN ADAMTS14	2.22e-03	23	57	2	IPR010294
Domain	Actinin_actin-bd_CS	FLNB FLNC	2.22e-03	23	57	2	IPR001589
Domain	ADAM_spacer1	PAPLN ADAMTS14	2.22e-03	23	57	2	PF05986
Domain	ACTININ_2	FLNB FLNC	2.22e-03	23	57	2	PS00020
Domain	ACTININ_1	FLNB FLNC	2.22e-03	23	57	2	PS00019
Domain	Chromo_domain	CHD9 CHD7	2.42e-03	24	57	2	IPR023780
Domain	Cys_knot_C	MUC2 SSPOP	2.62e-03	25	57	2	IPR006207
Domain	CTCK_2	MUC2 SSPOP	2.62e-03	25	57	2	PS01225
Domain	Chromo	CHD9 CHD7	2.84e-03	26	57	2	PF00385
Domain	CHROMO_1	CHD9 CHD7	3.29e-03	28	57	2	PS00598
Domain	CHROMO_2	CHD9 CHD7	3.29e-03	28	57	2	PS50013
Domain	-	FLNB FLNC ADAMTSL1 CSF3R VASN ICAM1 PAPLN	3.90e-03	663	57	7	2.60.40.10
Domain	Helicase_C	CHD9 CHD7 DDX60L	4.27e-03	107	57	3	PF00271
Domain	HELICc	CHD9 CHD7 DDX60L	4.27e-03	107	57	3	SM00490
Domain	SNF2_N	CHD9 CHD7	4.28e-03	32	57	2	IPR000330
Domain	Chromodomain-like	CHD9 CHD7	4.28e-03	32	57	2	IPR016197
Domain	SNF2_N	CHD9 CHD7	4.28e-03	32	57	2	PF00176
Domain	Helicase_C	CHD9 CHD7 DDX60L	4.39e-03	108	57	3	IPR001650
Domain	LRR_1	SLITRK2 IGFALS VASN CHADL	4.47e-03	219	57	4	PF00560
Domain	HELICASE_CTER	CHD9 CHD7 DDX60L	4.50e-03	109	57	3	PS51194
Domain	HELICASE_ATP_BIND_1	CHD9 CHD7 DDX60L	4.50e-03	109	57	3	PS51192
Domain	DEXDc	CHD9 CHD7 DDX60L	4.50e-03	109	57	3	SM00487
Domain	Chromo/shadow_dom	CHD9 CHD7	4.55e-03	33	57	2	IPR000953
Domain	CHROMO	CHD9 CHD7	4.55e-03	33	57	2	SM00298
Domain	Helicase_ATP-bd	CHD9 CHD7 DDX60L	4.62e-03	110	57	3	IPR014001
Domain	Ig-like_fold	FLNB FLNC ADAMTSL1 CSF3R VASN ICAM1 PAPLN	5.48e-03	706	57	7	IPR013783
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL1 ADAMTS14 SSPOP NOTCH3	3.59e-05	68	39	4	M27303
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL1 ADAMTS14 SSPOP	1.67e-04	39	39	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL1 ADAMTS14 SSPOP	1.67e-04	39	39	3	MM15165
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL1 ADAMTS14 MUC2 SSPOP	2.26e-04	109	39	4	MM15164
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB3 GRM1	3.31e-04	10	39	2	M47661
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB3 GRM1	4.04e-04	11	39	2	M49033
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNB FLNC	4.04e-04	11	39	2	M48099
Pathway	KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY	PLCB3 TG	4.84e-04	12	39	2	M47628
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB3 GRM1	5.71e-04	13	39	2	M47656
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTSL1 ADAMTS14 SSPOP NOTCH3	6.34e-04	143	39	4	M27275
Pathway	WP_GPR40_PATHWAY	PKD1 PLCB3	7.65e-04	15	39	2	M39526
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	PLCB3 GRM1	1.11e-03	18	39	2	M47659
Pubmed	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.	FCGBP MUC2	2.83e-06	2	59	2	19432394
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	2.83e-06	2	59	2	12525170
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	2.83e-06	2	59	2	9694715
Pubmed	The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.	FCGBP MUC2	2.83e-06	2	59	2	34126068
Pubmed	Filamin B mediates ICAM-1-driven leukocyte transendothelial migration.	FLNB ICAM1	2.83e-06	2	59	2	18809679
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTSL1 PAPLN ADAMTS14 SSPOP	8.30e-06	75	59	4	20637190
Pubmed	Expression of Apc2 during mouse development.	APC2 NOTCH3	8.48e-06	3	59	2	15018807
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNB FLNC	8.48e-06	3	59	2	11252955
Pubmed	Genome-wide transcriptional profiling analysis of all trans retinoic acid-treated tongue carcinoma SCC-9 cells.	IL32 ICAM1	8.48e-06	3	59	2	21725974
Pubmed	Human IL-32θA94V mutant attenuates monocyte-endothelial adhesion by suppressing the expression of ICAM-1 and VCAM-1 via binding to cell surface receptor integrin αVβ3 and αVβ6 in TNF-α-stimulated HUVECs.	IL32 ICAM1	8.48e-06	3	59	2	37228610
Pubmed	mGlu1 receptor canonical signaling pathway contributes to the opening of the orphan GluD2 receptor.	PLCB3 GRM1	8.48e-06	3	59	2	27276689
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	8.48e-06	3	59	2	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNB FLNC	8.48e-06	3	59	2	11153914
Pubmed	Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.	FCGBP MUC2	1.69e-05	4	59	2	28604600
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	MUC2 NOTCH3	1.69e-05	4	59	2	22691042
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNB FLNC	1.69e-05	4	59	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB FLNC	1.69e-05	4	59	2	22802962
Pubmed	Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.	PKD1 NOTCH3	1.69e-05	4	59	2	29463793
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	FLNB FLNC PKD1 TRIM39 FLACC1 NOTCH3	2.02e-05	329	59	6	17474147
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB FLNC	2.82e-05	5	59	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNB FLNC	2.82e-05	5	59	2	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNB FLNC	2.82e-05	5	59	2	17360453
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNB FLNC	5.91e-05	7	59	2	16076904
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FCGBP IGFALS VASN ICAM1 C9	7.66e-05	257	59	5	16335952
Pubmed	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.	PLCB3 GRM1	7.87e-05	8	59	2	9651375
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNB FLNC	7.87e-05	8	59	2	17145501
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DGCR2 FLNC PKD1 SLCO4A1 PAPLN WRAP53 ZBTB42 MBD3 RAI1	9.63e-05	1105	59	9	35748872
Pubmed	LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis.	IPO5 LAS1L	1.01e-04	9	59	2	22190735
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNB FLNC	1.01e-04	9	59	2	11807098
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO5 FLNB FLNC POP1 CHD7 LAS1L RAI1	1.17e-04	653	59	7	22586326
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	IPO5 POP1 CHD9 CHD7 LAS1L	1.18e-04	282	59	5	23667531
Pubmed	Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.	FLNB FCGBP MUC2	1.21e-04	56	59	3	20706999
Pubmed	The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.	FLNB FLNC	1.26e-04	10	59	2	36357400
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNB FLNC	1.54e-04	11	59	2	36579465
Pubmed	USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.	FLNB FLNC	1.54e-04	11	59	2	19015242
Pubmed	Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues.	ICAM1 MUC2	1.85e-04	12	59	2	25378482
Pubmed	Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.	FCGBP ICAM1	2.54e-04	14	59	2	32385093
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	IPO5 FLNB FLNC RANBP6	2.75e-04	184	59	4	23402259
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNB FLNC	4.25e-04	18	59	2	12119179
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	IPO5 POP1 CHD9 CHD7 RAI1	5.51e-04	394	59	5	27248496
Pubmed	The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.	POP1 LAS1L	5.82e-04	21	59	2	35232816
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNB FLNC	6.39e-04	22	59	2	18487259
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	FLNC CHD7 MBD3	7.07e-04	102	59	3	26584622
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ADAMTSL1 MARCHF6 SSPOP	7.69e-04	105	59	3	9628581
Pubmed	Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.	IGFALS TG	8.28e-04	25	59	2	23563309
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	FLNB NOTCH3	1.19e-03	30	59	2	19054571
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	IPO5 FLNB ICAM1 DDX60L C9 GNL1	1.28e-03	711	59	6	33022573
Pubmed	Genetic mapping of the human and mouse phospholipase C genes.	MAP1A PLCB3	1.44e-03	33	59	2	8672127
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB POP1 PKD1 PLCB3 SSPOP RAI1	1.53e-03	736	59	6	29676528
Pubmed	Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus.	IPO5 MAP1A	1.53e-03	34	59	2	25505242
Pubmed	The transcription factor RBP-J is essential for retinal cell differentiation and lamination.	GNL1 NOTCH3	1.53e-03	34	59	2	20017954
Pubmed	Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.	IPO5 KBTBD4 CLCN4 ICAM1	1.54e-03	292	59	4	12819125
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	FLNB FCGBP IGFALS VASN ICAM1 PKD1 C9	1.62e-03	1016	59	7	19056867
Cytoband	16p13.3	IL32 IGFALS VASN PKD1 RPUSD1	1.61e-05	244	59	5	16p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	IL32 IGFALS VASN PKD1 RPUSD1	2.23e-04	426	59	5	chr16p13
Cytoband	14q24.2	DPF3 PAPLN	4.78e-04	25	59	2	14q24.2
GeneFamily	ADAMTS like	ADAMTSL1 PAPLN	8.04e-05	7	36	2	947
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNB DPF3 VASN PYCARD-AS1 CHADL	1.56e-06	148	59	5	6cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FLNB ADAMTSL1 MAP1A VASN PAPLN	5.72e-06	193	59	5	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP IGFALS ADIG PAPLN NOTCH3	5.72e-06	193	59	5	1526f51b589a7dc7a28f35f0e788dc38d338d2bc
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	1.02e-05	3	55	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	1.02e-05	3	55	2	DOID:0111190 (implicated_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD7	7.12e-05	7	55	2	DOID:0050834 (implicated_via_orthology)
Disease	immature granulocyte measurement	NLRP12 CHD7	7.12e-05	7	55	2	EFO_0803543
Disease	ulcerative colitis (biomarker_via_orthology)	ICAM1 MUC2	1.22e-04	9	55	2	DOID:8577 (biomarker_via_orthology)
Disease	granulocyte percentage of myeloid white cells	FLNB NLRP12 CSF3R CHD9 CHD7	1.43e-04	268	55	5	EFO_0007997
Disease	allergic conjunctivitis (is_marker_for)	ICAM1 MUC2	1.52e-04	10	55	2	DOID:11204 (is_marker_for)
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	FLNC PKD1	3.06e-04	14	55	2	DOID:898 (implicated_via_orthology)
Disease	Graves' disease (is_marker_for)	ICAM1 TG	3.53e-04	15	55	2	DOID:12361 (is_marker_for)
Disease	Hodgkins lymphoma	ZNF526 FCGBP ATP13A5	4.89e-04	82	55	3	EFO_0000183
Disease	alkaline phosphatase measurement	ADAMTSL1 MAP1A NEIL2 PKD1 PRSS55 PAPLN FHIP2A RAI1	5.53e-04	1015	55	8	EFO_0004533
Disease	prion disease	POP1 ADAMTS14	5.72e-04	19	55	2	EFO_0004720
Disease	dilated cardiomyopathy	FLNC PKD1	6.34e-04	20	55	2	EFO_0000407
Disease	Inhalant adrenergic use measurement	RANBP6 CHADL MUC2	7.74e-04	96	55	3	EFO_0009941
Disease	Immunologic Deficiency Syndromes	CHD7 C9	8.42e-04	23	55	2	C0021051
Disease	Dwarfism	IGFALS TG	9.96e-04	25	55	2	C0013336
Disease	eosinophil measurement	NLRP12 RANBP6 CHD7	1.09e-03	108	55	3	EFO_0803540
Disease	colorectal cancer (implicated_via_orthology)	APC2 NOTCH3	1.44e-03	30	55	2	DOID:9256 (implicated_via_orthology)
Disease	Intellectual Disability	ZNF526 APC2 LAS1L FHIP2A RAI1	1.46e-03	447	55	5	C3714756
Disease	left ventricular mass index	FLNC ADAMTS14	1.84e-03	34	55	2	EFO_0009290

Protein segments in the cluster

Peptide	Gene	Start	Entry
QWRVWANCIPCPLQE	ATP13A5	56	Q4VNC0
CLDWEPWSKGPAEFC	ADIG	51	Q0VDE8
ELGWAQPCDVWSIGC	CLK3	496	P49761
PGLERLWLEGNPWDC	IGFALS	526	P35858
LWLEGNPWDCGCPLK	IGFALS	531	P35858
DWIIFRNWCRPGADC	CLCN4	496	P51793
CQPSLDLPEWWECGR	CHD7	2081	Q9P2D1
VPCPAQWRLGAWSQC	ADAMTS14	966	Q8WXS8
WPEENLGDACPRWGL	RAI1	746	Q7Z5J4
EAAACPAWERGAWPE	MAP1A	2381	P78559
DGLQRLTWWCPQCQP	NEIL2	306	Q969S2
LIYCTCWDPWNLGPR	FLACC1	6	Q96Q35
WECPALPQGWEREEV	MBD3	6	O95983
AEPPEGSWSCHLCWE	DPF3	351	Q92784
WETWPRAQELCPEEF	DDX60L	1021	Q5H9U9
CNLDPCPARWEIGKW	ADAMTSL1	661	Q8N6G6
CPARWEIGKWSPCSL	ADAMTSL1	666	Q8N6G6
DSCAPGLCPDWESWD	FLNB	176	O75369
PCVPLCNWTGWLDSG	MUC2	1781	Q02817
DPPRQENETWWLCDC	MUC2	4416	Q02817
QPVRVEDPDGCCWHW	MUC2	4461	Q02817
CWEVPRAWDSQGIPE	C19orf85	201	A0A1B0GUS0
DNCAPGLCPDWEAWD	FLNC	196	Q14315
GLCPDWEAWDPNQPV	FLNC	201	Q14315
VGDPWRQCEALQCWR	NOTCH3	1421	Q9UM47
FPLICGWWLDICSLE	MARCHF6	386	O60337
DWPRMVESCLGSPCW	LAS1L	461	Q9Y4W2
DPSAEHPWCAWDICE	GNL1	466	P36915
RPWPDRQWGLCIFDD	IPO5	876	O00410
LAPFCCPWEQLTQDW	POP1	701	Q99575
WGCRCVELDVWKGRP	PLCB3	356	Q01970
CETCWDWLQARDGGP	APC2	381	O95996
DLPVWWECGPHDRDL	CHD9	1956	Q3L8U1
GPWRDKDPALWCQLC	IL32	46	P24001
WRAPGWDPLCWDECR	FCGBP	4246	Q9Y6R7
WDPLCWDECRGSCPT	FCGBP	4251	Q9Y6R7
RLWLCQPAPRCGEWT	IGFL4	26	Q6B9Z1
AGCLQLCWEPWQPGL	CSF3R	246	Q99062
TIQCIPLPWQCDGWA	DGCR2	41	P98153
PLPWQCDGWATCEDE	DGCR2	46	P98153
DTWEWNELIPQGICP	KLHDC2	251	Q9Y2U9
PRLDERDCPGNWTWP	ICAM1	396	P05362
CAICLRWEWPGSPKA	FHIP2A	606	Q5W0V3
PLWCGCQARPLLEWL	CHADL	311	Q6NUI6
DLGWWPNADLTGCEP	GRM1	566	Q13255
SPWSEWSQCDPCLRQ	C9	46	P02748
PFECDCGLAWLPRWA	PKD1	126	P98161
RGPCLQWLSEWTLEP	RPUSD1	296	Q9UJJ7
WWEDLERDFPCPVCR	TRIM39	56	Q9HCM9
ECRLQLWWCGGAPDS	WRAP53	511	Q9BUR4
VLGSEGWCVWPRQCP	SSPOP	1856	A2VEC9
GWCVWPRQCPCLVDG	SSPOP	1861	A2VEC9
PLSEWSEWSPCGPCL	SSPOP	4526	A2VEC9
CNNATVDWEWCAPLP	KBTBD4	301	Q9NVX7
VDWEWCAPLPRDRLQ	KBTBD4	306	Q9NVX7
NPWNCTCDLLPLKAW	SLITRK2	216	Q9H156
CSSRPWPDRQWGLCI	RANBP6	881	O60518
CGWWAFAPPCLQVLN	SLCO4A1	86	Q96BD0
RIAEGNEPPWCFWDV	PIGV	286	Q9NUD9
LQRCAAWSPEPWGEC	PAPLN	421	O95428
PQRGSWVAPACLWAC	PYCARD-AS1	171	I3L0S3
GNCFPEWDGLICWPR	PTH2R	61	P49190
NCVCPLSWFGPWVRE	VASN	301	Q6EMK4
CLPTQPGPATWRECW	PRSS55	176	Q6UWB4
SGWEAPWVQQPRCCR	UNQ6494/PRO21346	61	Q6UXR6
CPWPVWTADLCPAAR	ZBTB42	141	B2RXF5
RPGDWDCPWCNAVNF	TEX13A	376	Q9BXU3
QCWDCQELFPSPELW	ZNF526	141	Q8TF50
LPWWETEAPLEDSQC	TG	1551	P01266
PQGPWCLCWEEKRPT	NLRP12	306	P59046