Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlactate dehydrogenase activity

LDHD LDHAL6A

9.16e-056502GO:0004457
GeneOntologyMolecularFunctiontransition metal ion binding

ARG2 DOHH GATAD1 FAXDC2 ADAM33 SAMHD1 FLG2 SHANK3 RABGGTB CRIP2

6.24e-0411895010GO:0046914
MousePhenoabnormal synchondrosis

PKD1 PFAS SIK3

1.10e-0516393MP:0004053
MousePhenopremature cranial synchondrosis closure

PKD1 PFAS

2.27e-053392MP:0030444
MousePhenosmall cecum

CFTR ZNF398

7.54e-055392MP:0009477
MousePhenoabnormal cranial synchondrosis

PKD1 PFAS

1.13e-046392MP:0030443
MousePhenodilated pancreatic duct

CFTR PKD1

2.10e-048392MP:0009144
MousePhenopremature endochondral bone ossification

PKD1 PFAS

2.10e-048392MP:0003417
MousePhenopancreas atrophy

CFTR PKD1

2.10e-048392MP:0013295
DomainHEAT

IPO5 DOHH CAND2

5.02e-0458503IPR000357
DomainHEAT_REPEAT

IPO5 DOHH CAND2

8.71e-0470503PS50077
DomainADAM_CR

ADAM15 ADAM33

1.05e-0318502PF08516
Domain-

ADAM15 ADAM33

1.29e-03205024.10.70.10
DomainDisintegrin

ADAM15 ADAM33

1.43e-0321502PF00200
DomainDISIN

ADAM15 ADAM33

1.43e-0321502SM00050
DomainACR

ADAM15 ADAM33

2.36e-0327502SM00608
DomainADAM_Cys-rich

ADAM15 ADAM33

2.36e-0327502IPR006586
DomainAnk_2

ASB18 PLA2G6 ASB15 SHANK3

2.60e-03215504PF12796
Domain-

ASB18 PLA2G6 ASB15 SHANK3

4.33e-032485041.25.40.20
DomainANK

ASB18 PLA2G6 ASB15 SHANK3

4.52e-03251504SM00248
DomainSOCS_box

ASB18 ASB15

4.64e-0338502PF07525
DomainANK_REPEAT

ASB18 PLA2G6 ASB15 SHANK3

4.65e-03253504PS50088
DomainAnkyrin_rpt-contain_dom

ASB18 PLA2G6 ASB15 SHANK3

4.71e-03254504IPR020683
DomainANK_REP_REGION

ASB18 PLA2G6 ASB15 SHANK3

4.71e-03254504PS50297
DomainPeptidase_M12B_N

ADAM15 ADAM33

4.89e-0339502IPR002870
DomainPep_M12B_propep

ADAM15 ADAM33

4.89e-0339502PF01562
DomainSOCS_box

ASB18 ASB15

4.89e-0339502SM00969
DomainSOCS

ASB18 ASB15

4.89e-0339502PS50225
DomainSOCS_box

ASB18 ASB15

4.89e-0339502IPR001496
DomainDISINTEGRIN_1

ADAM15 ADAM33

5.13e-0340502PS00427
DomainReprolysin

ADAM15 ADAM33

5.13e-0340502PF01421
DomainADAM_MEPRO

ADAM15 ADAM33

5.13e-0340502PS50215
DomainDISINTEGRIN_2

ADAM15 ADAM33

5.13e-0340502PS50214
DomainPeptidase_M12B

ADAM15 ADAM33

5.13e-0340502IPR001590
DomainAnkyrin_rpt

ASB18 PLA2G6 ASB15 SHANK3

5.26e-03262504IPR002110
DomainCYSTEINE_SWITCH

ADAM15 ADAM33

5.39e-0341502PS00546
DomainDisintegrin_dom

ADAM15 ADAM33

5.39e-0341502IPR001762
DomainPept_M10_metallopeptidase

ADAM15 ADAM33

5.91e-0343502IPR001818
DomainHEAT

IPO5 CAND2

7.32e-0348502PF02985
DomainLRRNT

PKD1 NYX

8.87e-0353502PF01462
DomainKelch-typ_b-propeller

KEAP1 KLHDC8B

9.53e-0355502IPR015915
DomainKelch

KEAP1 KLHDC8B

1.06e-0258502SM00612
Pubmed

Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.

CFTR PKD1

2.11e-06251226289599
Pubmed

Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation.

CFTR PKD1

2.11e-06251217108316
Pubmed

The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.

CFTR PKD1

2.11e-06251234473378
Pubmed

Expression of Crip2, a LIM-domain-only protein, in the mouse cardiovascular system under physiological and pathological conditions.

ENG CRIP2

4.41e-05751221601656
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CAND2 LDHAL6A PKD1 SIK3 FLG2 SHANK3

1.72e-0456451621565611
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOCAD PKD1 HELZ2 ZNF398 NLRC5 PFAS PLA2G6 WRAP53

1.92e-04110551835748872
Pubmed

Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis.

SCX TFAP2B

2.50e-041651233482080
Pubmed

ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.

ASB18 ASB15

2.83e-041751216325183
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

CFTR PKD1

2.83e-041751216472605
Pubmed

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1.

FBXO22 KEAP1

3.18e-041851231257023
Pubmed

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.

ADAM15 ADAM33

3.55e-041951215063736
Pubmed

Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.

PFAS KEAP1

6.19e-042551227621311
Pubmed

Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.

IPO5 CAND2

6.70e-042651223181366
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DLG5 EHHADH HELZ2 SAMHD1 KEAP1 WRAP53 FLG2 SLC39A7

8.04e-04137151836244648
Cytoband17p13.1

PFAS PLD2 WRAP53

3.15e-0411851317p13.1
CytobandEnsembl 112 genes in cytogenetic band chr7q31

TMEM168 CFTR ASB15

5.19e-04140513chr7q31
GeneFamilyAnkyrin repeat domain containing

ASB18 PLA2G6 ASB15 SHANK3

9.44e-04242334403
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM15 ADAM33

1.10e-032733247
GeneFamilyPhospholipases

PLA2G6 PLD2

2.66e-0342332467
GeneFamilySterile alpha motif domain containing

SAMHD1 SHANK3

1.12e-0288332760
CoexpressionGSE27786_LIN_NEG_VS_NKTCELL_UP

IPO5 TAS1R1 PLA2G6 WRAP53 RABGGTB CRIP2

2.48e-06200516M4787
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 PROCR ACKR1 ENG SHANK3 CRIP2

9.11e-0819451623f2a627226aaed468c55adc42ab22e051dfe7fe
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 PROCR ACKR1 ENG SHANK3 CRIP2

9.40e-08195516752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ACKR1 ENG SHANK3 CRIP2

9.40e-08195516cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ACKR1 ENG SHANK3 CRIP2

1.06e-0719951670e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

LTO1 PROCR ACKR1 ENG SHANK3

9.11e-07154515928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

1.53e-06171515b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAM15 PROCR ENG SHANK3 CRIP2

1.81e-061775155ff8dcfb030312126695d53a026d2e104a401b83
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 PROCR PFAS ACKR1 CRIP2

1.86e-061785155cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2 PIF1

1.86e-0617851560263c0bb9de3a57ba2ba543262a2ace0066fd85
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 PROCR PFAS ACKR1 CRIP2

1.86e-06178515f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ACKR1 ENG SHANK3

1.91e-06179515040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.07e-06182515d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.13e-06183515a644258ba90acc62d571623e429d72ffc4b69203
ToppCell5'-GW_trimst-2-LymphNode-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.18e-06184515df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.18e-061845151ace70f12b417185bdd46042833f72b3b6815966
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.24e-061855150ab1be455f2cd883c9d1522ca78112c37833352e
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 PROCR ACKR1 ENG CRIP2

2.36e-0618751564dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.36e-06187515d6765854154557794815514c0aa355bc74b8523e
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 PROCR ACKR1 ENG CRIP2

2.36e-06187515b535d5447bf15e95dcf025a0a455628b956fc857
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

2.43e-06188515366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell390C-Endothelial_cells-Endothelial-D-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.43e-0618851550481192da0e9484accb7fcbf9e28a246bb3b80f
ToppCell390C-Endothelial_cells-Endothelial-D|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.43e-0618851530bbd00297de7a2e3e6008aaf37ec0d0617315eb
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.56e-06190515141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD ASB18 SCUBE2 ASB15 SCX

2.62e-061915159d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD ASB18 SCUBE2 ASB15 SCX

2.62e-06191515543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

2.76e-061935152661ad9107ed9231e4afea4442a79051139a31df
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 PROCR ACKR1 ENG SHANK3

2.76e-06193515daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 PROCR ACKR1 ENG CRIP2

2.76e-061935150f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCellPCW_05-06-Endothelial-Endothelial_immature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

2.83e-061945159bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ACKR1 ENG SHANK3

2.90e-06195515ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG CRIP2

2.90e-061955150c15be3e7c238e329505dcbbe197a977d1019d45
ToppCell(6)_Endothelial-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.90e-06195515c0005a5f2dc63a0cc254c45ac89a2f42df6f8bde
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG CRIP2

2.90e-0619551545ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG CRIP2

2.90e-061955155b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 PROCR ACKR1 ENG SHANK3

2.90e-0619551577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.98e-061965159b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

2.98e-06196515a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

2.98e-0619651585b697db1c925eff8bbef9d74565c82be5a0ddcc
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.05e-06197515dfc052a447c3b32235fcaffdf06c4e0941723d19
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

3.05e-061975159b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 PROCR ACKR1 ENG CRIP2

3.05e-061975158437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.05e-061975157caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 PROCR ACKR1 ENG CRIP2

3.05e-061975150542badae77d2f606c13cfaf361319495c354351
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 PROCR ACKR1 ENG CRIP2

3.05e-06197515aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.05e-06197515951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 PROCR ACKR1 ENG CRIP2

3.05e-06197515a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.05e-06197515e8e879b7634a29569061d3515d180784094a31e7
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-061985154a70a1ab40fe30b90acd97e4e36067db62acc905
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-0619851544f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCell368C-Endothelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-061985159a2c2201baee51581733e183065298a97eba4553
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-061985155784e0f9988c917026a692a61b09c7e77e540d13
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

ADAM15 PROCR ACKR1 ENG CRIP2

3.13e-0619851570d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCell3'-Adult-LymphNode-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PROCR ACKR1 ENG SHANK3 CRIP2

3.13e-06198515f7c89588bc84415acf7488cfb7a86781cd998c69
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM15 PROCR ENG SHANK3 CRIP2

3.13e-061985151e83bec16dcd60460422625f89952ff506d6be51
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAM15 PROCR ENG SHANK3 CRIP2

3.13e-061985152630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell18-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

ADAM15 PROCR ACKR1 ENG CRIP2

3.13e-061985156b7f1b352dc3a803af87106ffb63944bd4286dfe
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-06198515f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.13e-0619851571ee440b1ac566db63d0b415c50a0ad064d14f15
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

3.13e-06198515dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-061995150d63da0afa93741c37609d879941de202d9ac86c
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-06199515f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-0619951533f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-06199515f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-06199515a8f2eb00c3e4267a174bc9eff307dc2e5d18c76e
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.21e-061995156a7ecc3a68b9cfc49e50abaeb16e2eee3795377e
ToppCellwk_20-22-Endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3 CRIP2

3.21e-0619951507be9509a8ec9c9a7d721912d77c20e841f49808
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-062005152e47888e041ec3d265425d1df97b6665c6da889c
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-062005159e44da8aaac239ed69d674dcd53800c5eaf397cb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-0620051550fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-06200515c55efd997392e99068b673542f56f1a209c5a6c8
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-0620051590061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCellParenchyma_COVID-19-Endothelial-TX-Bronchial_vessel|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-06200515a18817d36b2b30a32e1513d36174bf98dfea2a92
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM15 ACKR1 ENG SHANK3 CRIP2

3.28e-0620051571979bbcc035d5b8882f1502b5a8ef248aaba45a
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

ADAM15 ACKR1 ENG SHANK3

3.38e-051605140cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 PROCR ADAM33 FLG2

3.46e-051615144f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LDHAL6A PROCR KLHDC8B SHANK3

3.46e-05161514aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAM15 ACKR1 ENG SHANK3

3.90e-05166514f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM15 PROCR ACKR1 ENG

4.48e-05172514fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM15 PROCR ACKR1 ENG

4.48e-05172514745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ADAM15 ENG SHANK3 CRIP2

4.69e-05174514b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2

4.69e-0517451442735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell368C-Endothelial_cells-Endothelial-D|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG CRIP2

4.79e-05175514c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell368C-Endothelial_cells-Endothelial-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 ACKR1 ENG CRIP2

4.79e-05175514ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ACKR1 ENG CRIP2

5.12e-05178514aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2

5.12e-05178514360d7a987f91d6d721487a921824057ec31a7332
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAM15 PROCR ACKR1 ENG

5.12e-051785140139b42494c1186390b12106dea7957e2b6717c2
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2

5.12e-05178514462111b61f37338f97ac7dc6c7da1d4316b54445
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG

5.12e-05178514ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG

5.12e-0517851487b04753650e45f12299c8456fb980d6c0d5961c
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG

5.12e-05178514ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2

5.35e-05180514755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ACKR1 ENG CRIP2

5.35e-05180514fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LDHD ADAM15 PROCR ENG

5.35e-051805145861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ACKR1 ENG CRIP2

5.35e-05180514c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ACKR1 ENG CRIP2

5.35e-05180514178648429686e6d4e6f3aafc350130e819788ecf
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 PROCR ENG SHANK3

5.35e-051805147d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 PROCR ADAM33 ACKR1

5.35e-051805146c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 ENG SHANK3 CRIP2

5.35e-0518051497e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG

5.46e-0518151472c28baf4fd417ff4a7068603830d55074960144
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 PROCR ACKR1 ENG

5.46e-051815142ac4d3e8987d5a009d7908d8787e18165826202a
Drugbenzamyl

LDHD LDHAL6A CFTR

8.81e-079513CID000160884
DiseasePulmonary Cystic Fibrosis

CFTR ENG

9.65e-059492C0392164
DiseaseFibrocystic Disease of Pancreas

CFTR ENG

9.65e-059492C1527396
Diseasemyeloid white cell count

DLG5 LTO1 PKD1 ZNF398 NLRC5 ADAM33 SIK3 ACKR1

1.43e-04937498EFO_0007988
DiseaseCystic Fibrosis

CFTR ENG

1.47e-0411492C0010674
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 ENG

1.76e-0412492DOID:10941 (is_implicated_in)
DiseaseBody Weight

WRAP53 TFAP2B

2.80e-0415492C0005910
Diseasenevus count, cutaneous melanoma

NUDT18 PLA2G6 TFAP2B

4.72e-0491493EFO_0000389, EFO_0004632
Diseasewaist-hip ratio

NUDT18 CAND2 SCUBE2 CFTR PKD1 SIK3 ASB15 TFAP2B

8.59e-041226498EFO_0004343
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HELZ2 NLRC5 PLA2G6 SIK3

1.38e-03291494EFO_0008317, EFO_0020946
Diseasecholesteryl esters to total lipids in very large HDL percentage

NLRC5 SIK3

1.64e-0336492EFO_0022257

Protein segments in the cluster

PeptideGeneStartEntry
GNASLGGHLTHVLEG

PROCR

46

Q9UNN8
RLGCHGGGSQEVKEH

GRK3

436

P35626
LGGDHSLAIGTISGH

ARG2

116

P78540
DFVLVDGGCVLSHGH

CFTR

1336

P13569
GHSLGLDHDLPGNSC

ADAM15

351

Q13444
GHCDVLEHLIHKGGD

ASB15

221

Q8WXK1
LLGCHASLGHRLGAG

ACKR1

146

Q16570
EIGHSLGLSHDPDGC

ADAM33

346

Q9BZ11
GGEEAALALAEGLHC

DOHH

186

Q9BU89
EGLHCGSALFRHEVG

DOHH

196

Q9BU89
GCHLEGVAGHKEAHI

ENG

206

P17813
HGLDAGMGDSLSLHG

TFAP2B

156

Q92481
AGLAEAGHLEGHCLV

FBXO22

71

Q8NEZ5
GHGGLSCGLETSGHE

FLG2

236

Q5D862
GLQHLGRDHSDGICL

NUDT18

256

Q6ZVK8
GGRGALHEACLGGHT

ASB18

151

Q6ZVZ8
GGLELALGCHYRIAH

EHHADH

101

Q08426
ELGVHLCGGNLHGVF

DLG5

1511

Q8TDM6
HAGLMALSAIGEGCH

IPO5

376

O00410
KALGGSCHLGHLHLD

NLRC5

996

Q86WI3
EALELSLAGAHGHGV

INO80B

21

Q9C086
LVVADIHSLHCGGGP

PRR35

116

P0CG20
ECGGISASIGHDPHL

RABGGTB

81

P53611
CYGVLGVLDHLHGTD

FAXDC2

286

Q96IV6
GEILCHHCTGRGGAG

GATAD1

26

Q8WUU5
GSIVGHVGDGNFHCI

LDHD

416

Q86WU2
LALHGTCTGEHGIGM

LDHD

456

Q86WU2
HGTLHGAKIGSEIGC

LTO1

41

Q8WV07
IDGHIYAVGGSHGCI

KEAP1

421

Q14145
VAHQDGHLLVLGGCG

KLHDC8B

26

Q8IXV7
CGKTLTPGGHAEHDG

CRIP2

156

P52943
HCGHFLEVARELGSG

HELZ2

1866

Q9BYK8
GHLVGHLGDRLGDDL

CAND2

596

O75155
GGDGCFLRCHSGIHL

SCUBE2

466

Q9NQ36
IVHGLSVCGHGKAED

FOCAD

1236

Q5VW36
GLQHDAGPGALLHCS

PKD1

716

P98161
VHAGAFGDCGVLEHL

NYX

221

Q9GZU5
CHIGGTTLHAFAGIG

PIF1

261

Q9H611
ALLGGHQGGITHLCF

WRAP53

361

Q9BUR4
EHSLGVGYLAGCLVH

SAMHD1

166

Q9Y3Z3
CGASLGGHEHPDLSD

SIK3

1271

Q9Y2K2
THDHLLCLDGGGVKG

PLA2G6

476

O60733
VAHGLHQLLGCASGA

TAS1R1

396

Q7RTX1
GGGDALCCELLLHDH

SHANK3

226

Q9BYB0
YGTGHILLDNVHCEG

SSC4D

246

Q8WTU2
LGLLVAGLGGHDDLH

SLC39A7

21

Q92504
AGLHCLELGHTGEAG

PFAS

971

O15067
TLKDHLRSGHNGGCG

ZNF398

581

Q8TD17
AHGLFHELGNCLGGT

TMEM168

396

Q9H0V1
DFDGDGHMDHLLPGC

ITFG1

266

Q8TB96
HLGNVLLAGEACGDG

SCX

126

Q7RTU7
CGLRTHGELGGHPVS

PLD2

736

O14939
HSESCHGLILGEHGD

LDHAL6A

181

Q6ZMR3