Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-1A adrenergic receptor binding	ARRB1 ARRB2	4.97e-06	2	45	2	GO:0031691
GeneOntologyMolecularFunction	alpha-1B adrenergic receptor binding	ARRB1 ARRB2	1.49e-05	3	45	2	GO:0031692
GeneOntologyMolecularFunction	follicle-stimulating hormone receptor binding	ARRB1 ARRB2	1.49e-05	3	45	2	GO:0031762
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK1 IQSEC1 RALGDS IQSEC3 ARRB1 STXBP5 IQSEC2	1.28e-04	507	45	7	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK1 IQSEC1 RALGDS IQSEC3 ARRB1 STXBP5 IQSEC2	1.28e-04	507	45	7	GO:0030695
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK1 IQSEC1 RALGDS IQSEC3 IQSEC2	1.66e-04	231	45	5	GO:0005085
GeneOntologyMolecularFunction	angiotensin receptor binding	ARRB1 ARRB2	2.21e-04	10	45	2	GO:0031701
GeneOntologyMolecularFunction	arrestin family protein binding	ARRB1 ARRB2	3.23e-04	12	45	2	GO:1990763
GeneOntologyMolecularFunction	adrenergic receptor binding	ARRB1 ARRB2	1.33e-03	24	45	2	GO:0031690
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	DOCK1 IQSEC1 ROCK2 ABRA RALGDS IQSEC3 ARRB1 PLD1 F11R IQSEC2	1.88e-07	538	45	10	GO:0007264
GeneOntologyBiologicalProcess	regulation of cell junction assembly	DOCK1 IQSEC1 ROCK2 FGFR1 PTPN13 F11R IQSEC2 EPHA3	3.09e-07	309	45	8	GO:1901888
GeneOntologyBiologicalProcess	cell junction assembly	DOCK1 IQSEC1 ROCK2 FGFR1 PTPN13 THSD1 F11R IQSEC2 EPHA3	3.17e-06	569	45	9	GO:0034329
GeneOntologyBiologicalProcess	regulation of ARF protein signal transduction	IQSEC1 IQSEC3 IQSEC2	1.67e-05	23	45	3	GO:0032012
GeneOntologyBiologicalProcess	ARF protein signal transduction	IQSEC1 IQSEC3 IQSEC2	1.90e-05	24	45	3	GO:0032011
GeneOntologyBiologicalProcess	cell junction organization	DOCK1 IQSEC1 ROCK2 IQSEC3 FGFR1 PTPN13 THSD1 F11R IQSEC2 EPHA3	3.71e-05	974	45	10	GO:0034330
GeneOntologyBiologicalProcess	regulation of synapse assembly	DOCK1 IQSEC1 FGFR1 PTPN13 IQSEC2	7.62e-05	202	45	5	GO:0051963
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	IQSEC1 ABRA IQSEC3 ARRB1 F11R IQSEC2	8.11e-05	333	45	6	GO:0051056
GeneOntologyBiologicalProcess	positive regulation of nuclear cell cycle DNA replication	FGFR1 ATRX	9.71e-05	7	45	2	GO:0010571
GeneOntologyBiologicalProcess	positive regulation of Rho protein signal transduction	ABRA ARRB1 F11R	9.76e-05	41	45	3	GO:0035025
GeneOntologyBiologicalProcess	synapse organization	DOCK1 IQSEC1 ROCK2 IQSEC3 FGFR1 PTPN13 IQSEC2 EPHA3	1.03e-04	685	45	8	GO:0050808
GeneOntologyBiologicalProcess	cell-substrate junction organization	IQSEC1 ROCK2 THSD1 EPHA3	1.15e-04	115	45	4	GO:0150115
GeneOntologyBiologicalProcess	follicle-stimulating hormone signaling pathway	ARRB1 ARRB2	1.29e-04	8	45	2	GO:0042699
GeneOntologyBiologicalProcess	regulation of synapse organization	DOCK1 IQSEC1 ROCK2 FGFR1 PTPN13 IQSEC2	1.84e-04	387	45	6	GO:0050807
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	DOCK1 IQSEC1 ROCK2 FGFR1 PTPN13 PLD1 F11R STXBP5 IQSEC2 EPHA3	1.95e-04	1189	45	10	GO:0044087
GeneOntologyBiologicalProcess	regulation of synapse structure or activity	DOCK1 IQSEC1 ROCK2 FGFR1 PTPN13 IQSEC2	2.06e-04	395	45	6	GO:0050803
GeneOntologyBiologicalProcess	actin cytoskeleton organization	IQSEC1 ROCK2 ABRA IQSEC3 ARRB1 F11R IQSEC2 EPHA3	3.06e-04	803	45	8	GO:0030036
GeneOntologyBiologicalProcess	regulation of fibroblast growth factor production	ROCK2 FGFR1	4.17e-04	14	45	2	GO:0090270
GeneOntologyBiologicalProcess	fibroblast growth factor production	ROCK2 FGFR1	4.17e-04	14	45	2	GO:0090269
GeneOntologyBiologicalProcess	Rho protein signal transduction	ROCK2 ABRA ARRB1 F11R	4.45e-04	164	45	4	GO:0007266
GeneOntologyBiologicalProcess	positive regulation of DNA-templated DNA replication	FGFR1 ATRX	4.80e-04	15	45	2	GO:2000105
GeneOntologyBiologicalProcess	regulation of nuclear cell cycle DNA replication	FGFR1 ATRX	4.80e-04	15	45	2	GO:0033262
GeneOntologyBiologicalProcess	peptidyl-serine phosphorylation	ROCK2 TSSK6 ARRB1 ARRB2 SGK3	5.30e-04	307	45	5	GO:0018105
GeneOntologyBiologicalProcess	synapse assembly	DOCK1 IQSEC1 FGFR1 PTPN13 IQSEC2	5.38e-04	308	45	5	GO:0007416
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	IQSEC1 ARRB1 PLD1 ARRB2 SPI1 STXBP5 EPHA3	5.58e-04	667	45	7	GO:0060627
GeneOntologyBiologicalProcess	regulation of cell-substrate junction organization	IQSEC1 ROCK2 EPHA3	5.87e-04	75	45	3	GO:0150116
GeneOntologyBiologicalProcess	peptidyl-serine modification	ROCK2 TSSK6 ARRB1 ARRB2 SGK3	6.31e-04	319	45	5	GO:0018209
GeneOntologyBiologicalProcess	actin filament-based process	IQSEC1 ROCK2 ABRA IQSEC3 ARRB1 F11R IQSEC2 EPHA3	7.12e-04	912	45	8	GO:0030029
GeneOntologyBiologicalProcess	regulation of endothelial cell development	ROCK2 F11R	8.62e-04	20	45	2	GO:1901550
GeneOntologyBiologicalProcess	regulation of establishment of endothelial barrier	ROCK2 F11R	8.62e-04	20	45	2	GO:1903140
GeneOntologyBiologicalProcess	G protein-coupled receptor internalization	ARRB1 ARRB2	9.52e-04	21	45	2	GO:0002031
GeneOntologyBiologicalProcess	negative regulation of interleukin-12 production	ARRB2 TLR8	9.52e-04	21	45	2	GO:0032695
GeneOntologyBiologicalProcess	positive regulation of epithelial cell migration	DOCK1 IQSEC1 ROCK2 FGFR1	9.72e-04	202	45	4	GO:0010634
Domain	IQSEC_PH	IQSEC1 IQSEC3 IQSEC2	9.82e-09	3	41	3	IPR033742
Domain	IQ_SEC7_PH	IQSEC1 IQSEC3 IQSEC2	9.82e-09	3	41	3	PF16453
Domain	-	IQSEC1 IQSEC3 IQSEC2	4.39e-06	15	41	3	1.10.1000.11
Domain	Sec7	IQSEC1 IQSEC3 IQSEC2	4.39e-06	15	41	3	PF01369
Domain	Sec7_alpha_orthog	IQSEC1 IQSEC3 IQSEC2	4.39e-06	15	41	3	IPR023394
Domain	Sec7	IQSEC1 IQSEC3 IQSEC2	5.39e-06	16	41	3	SM00222
Domain	SEC7	IQSEC1 IQSEC3 IQSEC2	5.39e-06	16	41	3	PS50190
Domain	Sec7_dom	IQSEC1 IQSEC3 IQSEC2	5.39e-06	16	41	3	IPR000904
Domain	Arrestin_N	ARRB1 ARRB2	2.81e-05	4	41	2	IPR014753
Domain	Arrestin	ARRB1 ARRB2	2.81e-05	4	41	2	IPR000698
Domain	-	ARRB1 ARRB2	2.81e-05	4	41	2	2.60.40.840
Domain	Arrestin_CS	ARRB1 ARRB2	2.81e-05	4	41	2	IPR017864
Domain	ARRESTINS	ARRB1 ARRB2	2.81e-05	4	41	2	PS00295
Domain	-	ARRB1 ARRB2	9.81e-05	7	41	2	2.60.40.640
Domain	Arrestin_C	ARRB1 ARRB2	1.31e-04	8	41	2	IPR014752
Domain	-	IQSEC1 ROCK2 IQSEC3 PTPN13 PLD1 IQSEC2	1.96e-04	391	41	6	2.30.29.30
Domain	Arrestin-like_N	ARRB1 ARRB2	2.09e-04	10	41	2	IPR011021
Domain	Arrestin_C-like	ARRB1 ARRB2	2.09e-04	10	41	2	IPR011022
Domain	Arrestin_C	ARRB1 ARRB2	2.09e-04	10	41	2	PF02752
Domain	Arrestin_N	ARRB1 ARRB2	2.09e-04	10	41	2	PF00339
Domain	Arrestin_C	ARRB1 ARRB2	2.09e-04	10	41	2	SM01017
Domain	PH_dom-like	IQSEC1 ROCK2 IQSEC3 PTPN13 PLD1 IQSEC2	3.11e-04	426	41	6	IPR011993
Domain	PH	IQSEC1 ROCK2 IQSEC3 PLD1 IQSEC2	3.41e-04	278	41	5	SM00233
Domain	PH_DOMAIN	IQSEC1 ROCK2 IQSEC3 PLD1 IQSEC2	3.46e-04	279	41	5	PS50003
Domain	PH_domain	IQSEC1 ROCK2 IQSEC3 PLD1 IQSEC2	3.52e-04	280	41	5	IPR001849
Domain	IQ	IQSEC1 IQSEC3 IQSEC2	5.06e-04	71	41	3	PF00612
Domain	IQ_motif_EF-hand-BS	IQSEC1 IQSEC3 IQSEC2	1.01e-03	90	41	3	IPR000048
Domain	Kinase-like_dom	ROCK2 TSSK6 FGFR1 PTPN13 EPHA3 SGK3	1.10e-03	542	41	6	IPR011009
Domain	IQ	IQSEC1 IQSEC3 IQSEC2	1.11e-03	93	41	3	PS50096
Domain	Protein_kinase_ATP_BS	ROCK2 TSSK6 FGFR1 EPHA3 SGK3	1.38e-03	379	41	5	IPR017441
Domain	Ig_E-set	GBE1 ARRB1 ARRB2	1.53e-03	104	41	3	IPR014756
Domain	-	GBE1 GLB1	2.67e-03	35	41	2	3.20.20.80
Domain	Pkinase_C	ROCK2 SGK3	2.98e-03	37	41	2	IPR017892
Domain	Glyco_hydro_catalytic_dom	GBE1 GLB1	3.14e-03	38	41	2	IPR013781
Domain	PROTEIN_KINASE_ATP	ROCK2 TSSK6 FGFR1 EPHA3 SGK3	3.17e-03	459	41	5	PS00107
Domain	Pkinase_C	ROCK2 SGK3	3.83e-03	42	41	2	PF00433
Domain	Prot_kinase_dom	ROCK2 TSSK6 FGFR1 EPHA3 SGK3	4.15e-03	489	41	5	IPR000719
Domain	PX	PLD1 SGK3	4.20e-03	44	41	2	SM00312
Domain	PROTEIN_KINASE_DOM	ROCK2 TSSK6 FGFR1 EPHA3 SGK3	4.30e-03	493	41	5	PS50011
Domain	PX	PLD1 SGK3	5.18e-03	49	41	2	PF00787
Domain	PX	PLD1 SGK3	5.39e-03	50	41	2	PS50195
Domain	Phox	PLD1 SGK3	5.82e-03	52	41	2	IPR001683
Domain	Glycoside_hydrolase_SF	GBE1 GLB1	6.04e-03	53	41	2	IPR017853
Domain	AGC-kinase_C	ROCK2 SGK3	6.72e-03	56	41	2	IPR000961
Domain	AGC_KINASE_CTER	ROCK2 SGK3	6.72e-03	56	41	2	PS51285
Domain	S_TK_X	ROCK2 SGK3	6.72e-03	56	41	2	SM00133
Pathway	KEGG_ENDOCYTOSIS	IQSEC1 IQSEC3 ARRB1 PLD1 ARRB2 IQSEC2	5.83e-06	181	36	6	M1519
Pathway	PID_IL8_CXCR1_PATHWAY	ARRB1 PLD1 ARRB2	4.80e-05	28	36	3	M252
Pathway	PID_ARF6_PATHWAY	IQSEC1 ARRB1 ARRB2	9.46e-05	35	36	3	M86
Pathway	REACTOME_TGFBR3_REGULATES_TGF_BETA_SIGNALING	ARRB1 ARRB2	1.76e-04	8	36	2	M48252
Pathway	REACTOME_TGFBR3_REGULATES_TGF_BETA_SIGNALING	ARRB1 ARRB2	1.76e-04	8	36	2	MM17233
Pubmed	Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization.	RALGDS ARRB1 ARRB2	2.02e-09	3	45	3	12105416
Pubmed	The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq.	IQSEC1 ARRB1 ARRB2	1.69e-07	9	45	3	17846866
Pubmed	Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2.	ARRB1 ARRB2	1.64e-06	2	45	2	18703513
Pubmed	Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.	ARRB1 ARRB2	1.64e-06	2	45	2	17579607
Pubmed	Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function.	ARRB1 ARRB2	1.64e-06	2	45	2	28973019
Pubmed	β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signalling.	ARRB1 ARRB2	1.64e-06	2	45	2	26077142
Pubmed	Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.	ARRB1 ARRB2	1.64e-06	2	45	2	17426148
Pubmed	β-Arrestin-dependent ERK signaling reduces anxiety-like and conditioned fear-related behaviors in mice.	ARRB1 ARRB2	1.64e-06	2	45	2	34344831
Pubmed	Beta-arrestin-1 protein represses diet-induced obesity.	ARRB1 ARRB2	1.64e-06	2	45	2	21543334
Pubmed	LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1.	ARRB1 ARRB2	1.64e-06	2	45	2	34480046
Pubmed	ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation.	ARRB1 ARRB2	1.64e-06	2	45	2	36215165
Pubmed	Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1.	ARRB1 ARRB2	1.64e-06	2	45	2	17618287
Pubmed	Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.	ARRB1 ARRB2	1.64e-06	2	45	2	26103985
Pubmed	β-Arrestin 1 and 2 similarly influence μ-opioid receptor mobility and distinctly modulate adenylyl cyclase activity.	ARRB1 ARRB2	1.64e-06	2	45	2	34450275
Pubmed	G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization.	ARRB1 ARRB2	1.64e-06	2	45	2	9668034
Pubmed	Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.	ARRB1 ARRB2	1.64e-06	2	45	2	31622341
Pubmed	Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.	ARRB1 ARRB2	1.64e-06	2	45	2	16181421
Pubmed	Distinct synaptic localization patterns of brefeldin A-resistant guanine nucleotide exchange factors BRAG2 and BRAG3 in the mouse retina.	IQSEC1 IQSEC3	1.64e-06	2	45	2	22886754
Pubmed	Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.	ARRB1 ARRB2	1.64e-06	2	45	2	21855149
Pubmed	Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.	ARRB1 ARRB2	1.64e-06	2	45	2	18519945
Pubmed	Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts.	ARRB1 ARRB2	1.64e-06	2	45	2	26449263
Pubmed	The role of beta-arrestins in the formyl peptide receptor-like 1 internalization and signaling.	ARRB1 ARRB2	1.64e-06	2	45	2	17594911
Pubmed	Light-dependent regulation of the transcriptional activity of the mammalian gene for arrestin.	ARRB1 ARRB2	1.64e-06	2	45	2	7932878
Pubmed	Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.	ARRB1 ARRB2	1.64e-06	2	45	2	12582207
Pubmed	Deficiency of endothelial FGFR1 signaling via upregulation of ROCK2 activity aggravated ALI/ARDS.	ROCK2 FGFR1	1.64e-06	2	45	2	36969192
Pubmed	Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling.	ARRB1 ARRB2	1.64e-06	2	45	2	26927499
Pubmed	β-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways.	ARRB1 ARRB2	1.64e-06	2	45	2	22699970
Pubmed	beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.	ARRB1 ARRB2	1.64e-06	2	45	2	19349687
Pubmed	β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix.	ARRB1 ARRB2	1.64e-06	2	45	2	21411739
Pubmed	The Two β-Arrestins Regulate Distinct Metabolic Processes: Studies with Novel Mutant Mouse Models.	ARRB1 ARRB2	1.64e-06	2	45	2	35008921
Pubmed	Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.	ARRB1 ARRB2	1.64e-06	2	45	2	30541881
Pubmed	β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling.	ARRB1 ARRB2	1.64e-06	2	45	2	25134464
Pubmed	beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.	ARRB1 ARRB2	1.64e-06	2	45	2	11171997
Pubmed	Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestins.	ARRB1 ARRB2	1.64e-06	2	45	2	20589830
Pubmed	β-Arrestin2 mediates the initiation and progression of myeloid leukemia.	ARRB1 ARRB2	1.64e-06	2	45	2	22773819
Pubmed	Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.	ARRB1 ARRB2	1.64e-06	2	45	2	17418896
Pubmed	β-Arrestin2 mediates progression of murine primary myelofibrosis.	ARRB1 ARRB2	1.64e-06	2	45	2	29263312
Pubmed	β-Arrestins Regulate Stem Cell-Like Phenotype and Response to Chemotherapy in Bladder Cancer.	ARRB1 ARRB2	1.64e-06	2	45	2	30787175
Pubmed	beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.	ARRB1 ARRB2	1.64e-06	2	45	2	19896992
Pubmed	Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers.	ARRB1 ARRB2	1.64e-06	2	45	2	29330504
Pubmed	β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.	ARRB1 ARRB2	1.64e-06	2	45	2	27054338
Pubmed	Transduction of group I mGluR-mediated synaptic plasticity by β-arrestin2 signalling.	ARRB1 ARRB2	1.64e-06	2	45	2	27886171
Pubmed	Hepatic β-arrestin 2 is essential for maintaining euglycemia.	ARRB1 ARRB2	1.64e-06	2	45	2	28650340
Pubmed	Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing.	ARRB1 ARRB2	1.64e-06	2	45	2	8486659
Pubmed	Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade.	ARRB1 ARRB2	1.64e-06	2	45	2	34507982
Pubmed	β-arrestin expression in corticotroph tumor cells is modulated by glucocorticoids.	ARRB1 ARRB2	1.64e-06	2	45	2	32027601
Pubmed	β-arrestins negatively control human adrenomedullin type 1-receptor internalization.	ARRB1 ARRB2	1.64e-06	2	45	2	28427767
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	IQSEC1 IQSEC3 IQSEC2	1.93e-06	19	45	3	30674481
Pubmed	Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.	ARRB1 ARRB2	4.91e-06	3	45	2	18787115
Pubmed	Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.	PTPN13 CRIP2	4.91e-06	3	45	2	12839623
Pubmed	Identification of receptor binding-induced conformational changes in non-visual arrestins.	ARRB1 ARRB2	4.91e-06	3	45	2	24867953
Pubmed	β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells.	ARRB1 ARRB2	4.91e-06	3	45	2	26211463
Pubmed	β-Arrestin signal complex plays a critical role in adipose differentiation.	ARRB1 ARRB2	4.91e-06	3	45	2	23557604
Pubmed	β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.	ARRB1 ARRB2	4.91e-06	3	45	2	29734363
Pubmed	Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.	ARRB1 ARRB2	4.91e-06	3	45	2	22315403
Pubmed	Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness).	ARRB1 ARRB2	4.91e-06	3	45	2	10549660
Pubmed	Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus.	ARRB1 ARRB2	4.91e-06	3	45	2	12538596
Pubmed	Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins.	ARRB1 ARRB2	4.91e-06	3	45	2	17272726
Pubmed	Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific.	ARRB1 ARRB2	4.91e-06	3	45	2	11723231
Pubmed	Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.	ARRB1 ARRB2	4.91e-06	3	45	2	21642958
Pubmed	Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function.	ARRB1 ARRB2	4.91e-06	3	45	2	27013682
Pubmed	Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation.	ARRB1 ARRB2	4.91e-06	3	45	2	18952848
Pubmed	beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.	ARRB1 ARRB2	4.91e-06	3	45	2	20207744
Pubmed	Bradykinin-activated contractile signalling pathways in human myometrial cells are differentially regulated by arrestin proteins.	ARRB1 ARRB2	4.91e-06	3	45	2	25766502
Pubmed	β-Arrestin2 is a critical component of the GPCR-eNOS signalosome.	ARRB1 ARRB2	4.91e-06	3	45	2	32404425
Pubmed	Preferential β-arrestin signalling at low receptor density revealed by functional characterization of the human FSH receptor A189 V mutation.	ARRB1 ARRB2	4.91e-06	3	45	2	20801186
Pubmed	The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy.	ARRB1 ARRB2	4.91e-06	3	45	2	26702092
Pubmed	The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.	ARRB1 ARRB2	4.91e-06	3	45	2	14500724
Pubmed	A family of retinal S-antigens (arrestins) and their genes: comparative analysis of human, mouse, rat, bovine and Drosophila.	ARRB1 ARRB2	4.91e-06	3	45	2	1458825
Pubmed	Beta-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-gamma (PPARgamma).	ARRB1 ARRB2	4.91e-06	3	45	2	21700709
Pubmed	beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.	ARRB1 ARRB2	4.91e-06	3	45	2	15173580
Pubmed	β-arrestin is critical for early shear stress-induced Akt/eNOS activation in human vascular endothelial cells.	ARRB1 ARRB2	4.91e-06	3	45	2	28062183
Pubmed	Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.	ARRB1 ARRB2	4.91e-06	3	45	2	25658948
Pubmed	KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse.	ARRB1 ARRB2	4.91e-06	3	45	2	25147978
Pubmed	Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.	ARRB1 ARRB2	4.91e-06	3	45	2	28581517
Pubmed	β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas: role in the regulation of response to somatostatin analogue treatment in patients with acromegaly.	ARRB1 ARRB2	4.91e-06	3	45	2	24169548
Pubmed	Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).	ARRB1 ARRB2	4.91e-06	3	45	2	23449980
Pubmed	Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons.	ARRB1 ARRB2	4.91e-06	3	45	2	32537493
Pubmed	Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1.	ARRB1 ARRB2	4.91e-06	3	45	2	16580177
Pubmed	Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.	ARRB1 ARRB2	4.91e-06	3	45	2	9169477
Pubmed	Direct binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptor.	ARRB1 ARRB2	4.91e-06	3	45	2	11259507
Pubmed	Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization.	ARRB1 ARRB2	4.91e-06	3	45	2	17525124
Pubmed	Roles of G protein and beta-arrestin in dopamine D2 receptor-mediated ERK activation.	ARRB1 ARRB2	4.91e-06	3	45	2	18940181
Pubmed	Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway.	ARRB1 ARRB2	4.91e-06	3	45	2	22025682
Pubmed	Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2.	ARRB1 ARRB2	4.91e-06	3	45	2	12393857
Pubmed	Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells.	RALGDS ARRB1	4.91e-06	3	45	2	20448034
Pubmed	beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform.	ARRB1 ARRB2	4.91e-06	3	45	2	15699339
Pubmed	The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.	ARRB1 ARRB2	4.91e-06	3	45	2	23818521
Pubmed	Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins.	ARRB1 ARRB2	4.91e-06	3	45	2	16611986
Pubmed	Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis.	ARRB1 ARRB2	4.91e-06	3	45	2	33710266
Pubmed	Phosphorylation of key serine residues is required for internalization of the complement 5a (C5a) anaphylatoxin receptor via a beta-arrestin, dynamin, and clathrin-dependent pathway.	ARRB1 ARRB2	4.91e-06	3	45	2	12464600
Pubmed	β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility.	ARRB1 ARRB2	4.91e-06	3	45	2	27911784
Pubmed	Analysis of temporal patterns of GPCR-β-arrestin interactions using split luciferase-fragment complementation.	ARRB1 ARRB2	4.91e-06	3	45	2	23302795
Pubmed	Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning.	ARRB1 ARRB2	4.91e-06	3	45	2	22308427
Pubmed	Distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of C3a receptor signaling in human mast cells.	ARRB1 ARRB2	4.91e-06	3	45	2	21589858
Pubmed	Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.	ARRB1 ARRB2	4.91e-06	3	45	2	21757712
Pubmed	Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone.	ARRB1 ARRB2	4.91e-06	3	45	2	21630325
Pubmed	Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.	ARRB1 ARRB2	4.91e-06	3	45	2	15489220
Pubmed	5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling.	ARRB1 ARRB2	4.91e-06	3	45	2	17377064
Pubmed	Prolonged photoresponses in transgenic mouse rods lacking arrestin.	ARRB1 ARRB2	4.91e-06	3	45	2	9333241
Interaction	CRHR1 interactions	PTPN13 ARRB1 ARRB2	1.35e-05	21	45	3	int:CRHR1
Interaction	EIF2AK4 interactions	AK9 ARRB1 ARRB2 HDLBP	2.61e-05	77	45	4	int:EIF2AK4
Interaction	PARD3 interactions	FGFR1 PTPN13 F11R KIAA1217 EPHA3 HDLBP	4.99e-05	298	45	6	int:PARD3
Interaction	AP3B1 interactions	ARRB1 PLD1 ARRB2 ATRX HDLBP	5.90e-05	187	45	5	int:AP3B1
Interaction	POLR1C interactions	ROCK2 PUM3 ARRB1 ARRB2 DDX18 RPAP2	6.32e-05	311	45	6	int:POLR1C
Interaction	RALGDS interactions	RALGDS ARRB1 ARRB2	7.05e-05	36	45	3	int:RALGDS
Cytoband	Xq21.1	ATRX APOOL	4.87e-04	33	45	2	Xq21.1
GeneFamily	Classical arrestins	ARRB1 ARRB2	1.29e-05	4	27	2	1312
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	PUM3 ERAP1	2.62e-03	51	27	2	870
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	FGFR1 ABCG2 F11R TLR8	2.62e-03	394	27	4	471
GeneFamily	X-linked mental retardation\|Angiotensin receptors	ATRX IQSEC2	2.82e-03	53	27	2	103
Coexpression	JOHNSTONE_PARVB_TARGETS_3_UP	FGFR1 ABCG2 ARRB1 PLD1 F11R GLB1 SGK3	7.23e-06	433	44	7	M2240
Coexpression	GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN	DOCK1 RALGDS PTPN13 ARRB2 CNOT3	1.90e-05	196	44	5	M5194
CoexpressionAtlas	Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3	DOCK1 MPEG1 GBE1 FGFR1 PLD1 GLB1 TLR8	2.57e-05	438	43	7	GSM605850_500
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3	DOCK1 MPEG1 GBE1 FGFR1 PLD1 GLB1 TLR8	2.68e-05	441	43	7	GSM605862_500
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1 TLR8	1.29e-06	188	45	5	4e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1 TLR8	1.54e-06	195	45	5	1d58585557bf8e9ce4d514e128d3a902b526331d
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PABPC4L IQSEC3 FGFR1 KIAA1217 CRIP2	1.54e-06	195	45	5	22a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell	facs-Skin-nan-18m-Myeloid-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 IQSEC3 SPI1 TLR8	1.55e-05	149	45	4	23a1b95c12f2e3708dc003e13fab423e89821f11
ToppCell	facs-Skin-nan-18m-Myeloid\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 IQSEC3 SPI1 TLR8	1.55e-05	149	45	4	bb18a18b891af85849b9658d774053f839c9a8e1
ToppCell	facs-Skin-nan-18m-Myeloid-macrophage\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 IQSEC3 SPI1 TLR8	1.55e-05	149	45	4	c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	1.85e-05	156	45	4	c841faa1695ff577b0774f531adf1343d05dce9e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	1.85e-05	156	45	4	21baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCell	facs-MAT-Fat-18m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.05e-05	160	45	4	bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD1 F11R CRIP2 SGK3	2.20e-05	163	45	4	c21114826bee1b05b411984326fef6b6e0d05316
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD1 F11R CRIP2 SGK3	2.20e-05	163	45	4	5d49414432db259a19df50d7944581d00b69f537
ToppCell	droplet-Heart-nan-3m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.26e-05	164	45	4	df9fe446c1a43100048e11c01bf009bec3414dcf
ToppCell	facs-Heart-LA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.31e-05	165	45	4	be7e18d798e81e4b0f3080054aa222c6913e350b
ToppCell	facs-Heart-LA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.31e-05	165	45	4	941a5b95164eaea47c3e6376e358f94c15b98312
ToppCell	facs-Kidney-nan-3m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.42e-05	167	45	4	991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCell	facs-Kidney-nan-3m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.42e-05	167	45	4	934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCell	facs-Kidney-nan-3m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.42e-05	167	45	4	f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCell	droplet-Heart-nan-3m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.42e-05	167	45	4	47447bcf184b1ad24ef17e135199fe7cd1d73c02
ToppCell	droplet-Heart-nan-3m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.48e-05	168	45	4	a4eebc78babb9b5ef33065b0642793820195a613
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPEG1 ARRB2 SPI1 TLR8	2.60e-05	170	45	4	f524b73d65941ebef7671c46df4362a3f15d24fc
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPEG1 ARRB2 SPI1 TLR8	2.66e-05	171	45	4	26755e43d94e934106fc19ab929e4d34c17d6cba
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD1 F11R CRIP2 DNAH17	2.72e-05	172	45	4	490745024730df6357f6c2b81d7a64e21557c0d5
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPEG1 ARRB2 SPI1 TLR8	2.72e-05	172	45	4	f0e767a20d93e546ce278db67dbd779cc68af533
ToppCell	facs-Heart-RA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.78e-05	173	45	4	5058cb5e3f2d57dbe947e1b113eb2bef7bf6dd7d
ToppCell	facs-Heart-RA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.78e-05	173	45	4	4fa5f502fa3ff8f888e279f68a0dafd91b37f26f
ToppCell	facs-Heart-RA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 SPI1 TLR8	2.78e-05	173	45	4	ea406b47ff3ead992bc06f6b1707c76eee574782
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 ATRX TLR8 HDLBP	2.97e-05	176	45	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 PTPN13 PLD1 DNAH17	2.97e-05	176	45	4	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	DOCK1 FGFR1 PTPN13 KIAA1217	3.11e-05	178	45	4	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	CV-Severe-4\|Severe / Virus stimulation, Condition and Cluster	GBE1 PUM3 IQSEC3 KIAA1217	3.25e-05	180	45	4	cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1	3.32e-05	181	45	4	8657d35cd3dff6c89d0fde67d7e7e81e1d6c8884
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	3.32e-05	181	45	4	7b6454972041a9b4e4ff2f313e8432d9040b8544
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Monocytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	3.39e-05	182	45	4	1fb9bdf2e9f0a9c230f109b471672f9c31e27c82
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 MPEG1 ATRX TLR8	3.39e-05	182	45	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	3.54e-05	184	45	4	ba260f8a2e6e510141a6b9c458eb0040acff0352
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 MPEG1 ATRX TLR8	3.61e-05	185	45	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	3.69e-05	186	45	4	69b107ad88b07e9aeef09d4e4dac99b0cb6b467e
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	IQSEC3 ABCG2 SPI1 TLR8	3.69e-05	186	45	4	ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	3.77e-05	187	45	4	8e1d6d25db5b5c91a651bb2d66edfcf073a31704
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCG2 THSD1 F11R CRIP2	3.85e-05	188	45	4	4dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCG2 THSD1 F11R CRIP2	3.85e-05	188	45	4	d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCG2 THSD1 F11R CRIP2	3.85e-05	188	45	4	1e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	IQSEC1 SPI1 ERAP1 TLR8	3.93e-05	189	45	4	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.09e-05	191	45	4	94c7da03e5264f4d73bb507ce339a935d90279a0
ToppCell	facs-Brain_Myeloid\|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 ARRB2 F11R SPI1	4.09e-05	191	45	4	bf1135b382a3bf8cddc19538bc38361ef1fc2de1
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.09e-05	191	45	4	1e668d67bc254ea15518e2c7a029a61087609b7a
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IQSEC3 ARRB2 SPI1 SGK3	4.18e-05	192	45	4	bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.18e-05	192	45	4	62eac1b8aed4fb924946b58c0237313f697a0136
ToppCell	Monocytes-Inflammatory_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MPEG1 ARRB1 SPI1 TLR8	4.18e-05	192	45	4	4be5c2c946337cd3e710137726358adca563f146
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.18e-05	192	45	4	e2fa1ba26d28953f0d35d95764b5dbe0b93a1191
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Granulocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.18e-05	192	45	4	161f4626571b1bce5758fad1fe5ce41a4621771d
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ARRB2 SPI1 TLR8	4.26e-05	193	45	4	cb0fb21510124883e716780bea46575620c366b8
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ARRB2 SPI1 TLR8	4.26e-05	193	45	4	0c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Monocytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	MPEG1 ARRB2 SPI1 TLR8	4.26e-05	193	45	4	ddbd8944661ac3b0b5fe63471bdc24ba05598017
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ARRB2 SPI1 TLR8	4.26e-05	193	45	4	0fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCell	medial-2-Hematologic-Nonclassical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ARRB2 SPI1 TLR8	4.35e-05	194	45	4	202e5070728191c46161fa7d931f00be1c7559d4
ToppCell	medial-Hematologic-Nonclassical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ARRB2 SPI1 TLR8	4.35e-05	194	45	4	002cd317732fc6b0d9a72fb46199f71db5a638a7
ToppCell	(2)_Mono_macro\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MPEG1 ARRB2 SPI1 TLR8	4.35e-05	194	45	4	7c05525614ee8cdfcbf22cce9146a8e73af7d14e
ToppCell	medial-Hematologic-Nonclassical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ARRB2 SPI1 TLR8	4.35e-05	194	45	4	ac203d388a3a3884e316dec0dcbd408e43c6ef6c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	f8908657db50f1c58904dd6fee4fc23f5ae3eed6
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	01da7115e38c280fb0baff2032b62bdb609bad5e
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ABCG2 ARRB2 SPI1	4.44e-05	195	45	4	c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCell	distal-Hematologic-Nonclassical_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	935461e849ca4d17627341b3ae5124d497793a91
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	aa3914e277918299dc7d2995c0c72288462ad43d
ToppCell	Monocytes-NUPR1+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	5e12201ce7ba912e7faa123ca200e609252ba288
ToppCell	distal-2-Hematologic-Nonclassical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ARRB2 SPI1 TLR8	4.44e-05	195	45	4	34bed73e4dae34b0f1076b7ff9dc7ea2096c1796
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1	4.44e-05	195	45	4	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MPEG1 ARRB1 ARRB2 SPI1	4.53e-05	196	45	4	51fc8bb9a806f8fbf78d5d80d535f1068a9770c2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1	4.53e-05	196	45	4	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|COVID-19_Moderate / disease group, cell group and cell class	MPEG1 ARRB1 SPI1 TLR8	4.53e-05	196	45	4	256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCell	Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	f811958823380069077754283e36106d80147494
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	894f9943404cf252dbdf9e5769d9238f982ba8b8
ToppCell	Monocytes-IL1B+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	7bc0735d324ac5a1661434cda4116ddd58296730
ToppCell	remission-Non-classical_Monocyte\|remission / disease stage, cell group and cell class	MPEG1 ARRB1 SPI1 TLR8	4.53e-05	196	45	4	049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCell	wk_15-18-Hematologic-Myeloid-S100A12-hi_cla._mono.\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	aa53ae1e5d08d31cfd81b7fae46c2b5d21d4f9b2
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.53e-05	196	45	4	63b841457d12fb9dd25630e3c348d3ef53463f86
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ABCG2 ARRB2 SPI1	4.62e-05	197	45	4	1c0024049db2d2c817a7f503de235b9630b24e33
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ABCG2 ARRB2 SPI1	4.62e-05	197	45	4	759f26753f76af3ae8d8527c4d221206245a3d45
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.62e-05	197	45	4	555ea43eccc3eb22be230c27e13d8b3b64c2a61f
ToppCell	wk_20-22-Hematologic-Myeloid-S100A12-hi_cla._mono.\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MPEG1 ARRB2 SPI1 TLR8	4.62e-05	197	45	4	e862561f61a1ae1ec858b34f8d9c9a7dc8894104
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.62e-05	197	45	4	2efb5acd56b96e5afd8d72b927f1d53cc443766f
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	IQSEC3 ABCG2 ARRB2 SPI1	4.62e-05	197	45	4	eecb693367510da20a6b1e9355e68785a1e3b85c
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ARRB2 SPI1 TLR8	4.62e-05	197	45	4	e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPEG1 ARRB2 SPI1 TLR8	4.62e-05	197	45	4	4d3670456655248250d156f92de01df4aa481733
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DOCK1 FGFR1 THSD1 CRIP2	4.71e-05	198	45	4	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	d681aff379720261d85f9c1c6030932c5046960e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	8fe5e6b563bee2179b0f17d6591870d7dd76e891
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1	4.71e-05	198	45	4	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	remission-Non-classical_Monocyte\|World / disease stage, cell group and cell class	MPEG1 ARRB1 SPI1 TLR8	4.71e-05	198	45	4	1c170655070acca00520b7cf9c510a04c0a90a8f
ToppCell	Immune\|World / Lineage, Cell type, age group and donor	IQSEC1 ARRB2 SPI1 SGK3	4.71e-05	198	45	4	65681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	187a04d498f0b355cb11c81172721698818082d6
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	a6aa113f0af4d25c032f440c3134fe4d88ca5055
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	c00dbe61dc25602f19bd42a760646680002961ca
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	a0ceed8689d42be6b9cde89d6c182d10b3fb14fc
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	6d547122b8c4ddbdd0d3dae3bce4a125740d5457
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DOCK1 FGFR1 THSD1 CRIP2	4.71e-05	198	45	4	122215d9288533ad03562cf777e846504863df9a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPEG1 ARRB1 ARRB2 SPI1	4.71e-05	198	45	4	623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic\|lymph-node_spleen / Manually curated celltypes from each tissue	MPEG1 ARRB2 SPI1 TLR8	4.71e-05	198	45	4	065c8a9655d19f93dfdb453c78bbfe7d857caf3e
ToppCell	wk_20-22-Hematologic-Myeloid-SPP1+_Mac\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MPEG1 ABCG2 ARRB2 SPI1	4.80e-05	199	45	4	7c19f1b1f4369edd035ca9cdcf4e653771fc4648
Drug	Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A	IQSEC1 ROCK2 ARMCX5 THSD1 EPHA3	3.58e-05	190	45	5	3379_DN
Drug	2,2,2-trifluoroethanethiol	ARRB1 ARRB2	3.81e-05	5	45	2	CID004133924
Drug	Androsterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A	DOCK1 FGFR1 ARRB1 RNFT2 EPHA3	3.95e-05	194	45	5	5696_DN
Drug	Megestrol acetate [595-33-5]; Up 200; 10.4uM; HL60; HT_HG-U133A	IQSEC1 FGFR1 PLD1 F11R DNAH17	4.05e-05	195	45	5	3091_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	RALGDS FGFR1 ARRB1 ARRB2 EPHA3	4.15e-05	196	45	5	5679_DN
Drug	Hydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A	FGFR1 TEF ATRX ERAP1 IQSEC2	4.15e-05	196	45	5	1687_UP
Drug	Nifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A	DOCK1 ARRB1 ARRB2 RNFT2 HDLBP	4.15e-05	196	45	5	1692_DN
Drug	Trimipramine maleate salt [521-78-8]; Down 200; 9.8uM; HL60; HT_HG-U133A	ABCG2 F11R ERAP1 IQSEC2 EPHA3	4.25e-05	197	45	5	3004_DN
Drug	Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A	ABCG2 F11R ATRX ERAP1 IQSEC2	4.25e-05	197	45	5	3750_DN
Drug	Nilutamide [63612-50-0]; Up 200; 12.6uM; HL60; HT_HG-U133A	FGFR1 ARRB1 ERAP1 DNAH17 IQSEC2	4.36e-05	198	45	5	3104_UP
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; PC3; HT_HG-U133A	FGFR1 ABCG2 PLD1 TEF DNAH17	4.36e-05	198	45	5	4594_UP
Drug	Trichlorfon [52-68-6]; Up 200; 15.6uM; PC3; HT_HG-U133A	RALGDS FGFR1 THSD1 DNAH17 IQSEC2	4.46e-05	199	45	5	7287_UP
Drug	Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; HL60; HT_HG-U133A	IQSEC1 CFAP74 PTPN13 PLD1 F11R	4.57e-05	200	45	5	2190_UP
Drug	Flavone	GBE1 ABCG2 GLB1 BCO1	4.91e-05	102	45	4	CID000010680
Disease	thrombin generation potential measurement, thrombomodulin measurement	RALGDS PUM3	5.51e-05	8	42	2	EFO_0005538, EFO_0007774
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	ABCG2 SPI1 CNOT3	5.98e-05	53	42	3	C1961099
Disease	Mental Retardation, X-Linked	ATRX IQSEC2	7.84e-04	29	42	2	C1136249
Disease	tea consumption measurement	ABCG2 TEF EPHA3	8.27e-04	129	42	3	EFO_0010091
Disease	Large cell carcinoma of lung	FGFR1 EPHA3	9.55e-04	32	42	2	C0345958
Disease	Squamous cell carcinoma of lung	FGFR1 EPHA3	9.55e-04	32	42	2	C0149782
Disease	triglyceride measurement, response to diuretic	KIAA1217 DDX18	1.08e-03	34	42	2	EFO_0004530, GO_0036270
Disease	lung squamous cell carcinoma (is_marker_for)	PTPN13 ATRX	1.21e-03	36	42	2	DOID:3907 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TGKIYSIKEFKEVEK	FAM228B	176	P0C875
EKKKKITVFKEISYT	ABCG2	356	Q9UNQ0
LNKGSVKTKFYVLKV	ARMCX5	441	Q6P1M9
GIIVSYKVKVKLVVS	ARRB1	316	P49407
TKTVKKIKVSVRQYA	ARRB2	226	P32121
FKVVERETKTKAYSK	CNOT3	91	O75175
KVIVKTMKTYVEKVA	PUM3	381	Q15397
VITLAIYGTRKFKKK	MPEG1	671	Q2M385
QYKKVTASKVFLAIK	MSL3P1	206	P0C860
VVTKIFQKKKNSVTY	IQSEC1	786	Q6DN90
VTKIFQKKKILVTYS	IQSEC2	1006	Q5JU85
KFAYGKVTLEKLKTV	GLB1	371	P16278
SVSKITKSGVKVSVY	ERAP1	256	Q9NZ08
FGYQKTKKVEKSKIF	DDX18	641	Q9NVP1
VTYVTKVEKSIVGMK	IQSEC3	846	Q9UPP2
SKTTAKVTKELYVKL	ATRX	576	P46100
KLKVVITSKSGEILY	GBE1	141	Q04446
KYLAKTGETFVKLVV	DOCK1	1161	Q14185
SLKSKGVYFIKTKSE	DNAH17	71	Q9UFH2
VGSVIVYKMKSGTKK	FGFR1	391	P11362
KEISVAIKTLKVGYT	EPHA3	646	P29320
YDFVLKKRTFTKGVK	RALGDS	876	Q12967
KKVYFAEKVTSLGKD	CRIP2	131	P52943
EKKKRFTVYKVLVSV	SGK3	26	Q96BR1
KVYKKKITLVNTTYT	CFAP74	531	Q9C0B2
KVKKTTQVKDYSFVT	PTPN13	1481	Q12923
VYGVKTKQIRKSVIK	OR52N5	301	Q8NH56
LKDVFSKYGKTLSVK	PABPC4L	206	P0CB38
LVSARKGSKFKKITY	APOOL	126	Q6UXV4
FDRTKKGTSSKKVIY	F11R	266	Q9Y624
KIILAVKSKGKFYLV	RNFT2	286	Q96EX2
KSGKTTVAKKITSEY	AK9	1421	Q5TCS8
EFKIKVGKKETETKY	PLD1	281	Q13393
TGTKTGKKTLQVVVY	KIAA1217	1591	Q5T5P2
VGKCKTIVSKYETKY	TEF	286	Q10587
VKKVKKKLTYQFSGE	SPI1	241	P17947
QVLYKLKTSKVFEKS	STXBP5	471	Q5T5C0
KKEVSKTVVSKTYER	ABRA	106	Q8N0Z2
TSIVEKGKTKYVIFK	BCO1	186	Q9HAY6
KGKTKYVIFKIPATV	BCO1	191	Q9HAY6
LVKEKSKIYEKTFTL	ZNF567	106	Q8N184
INQSKKTVFVLTKKY	TLR8	936	Q9NR97
KYKISTKTNKVYDIT	RPAP2	116	Q8IXW5
KKKGLTETTKVYHVS	THSD1	541	Q9NS62
VKKYVIVSSKKILFY	ROCK2	1171	O75116
VKVATSKKYKGTVAI	TSSK6	26	Q9BXA6
SKKYKGTVAIKVVDR	TSSK6	31	Q9BXA6
KIYEEKKKKTTTIAV	HDLBP	286	Q00341