Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	complement component C3b receptor activity	CR1 CR1L	3.64e-05	2	121	2	GO:0004877
GeneOntologyMolecularFunction	complement component C4b receptor activity	CR1 CR1L	3.64e-05	2	121	2	GO:0001861
GeneOntologyMolecularFunction	complement binding	CFH CR1 CR1L CFB	4.05e-05	32	121	4	GO:0001848
GeneOntologyMolecularFunction	complement component C3b binding	CFH CR1 CR1L	4.59e-05	12	121	3	GO:0001851
GeneOntologyMolecularFunction	complement component C4b binding	CR1 CR1L	1.09e-04	3	121	2	GO:0001855
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GPR22 GPR37 ADGRB3 OR2H1 CR1 CR1L PLXNB2 CHRM5 ADGRG4 OR4L1 IFNAR1 UNC5A CD3D OR10AG1 PTPRH NGF CD69 HTR3D ADGRF5 ADGRF1	1.77e-04	1353	121	20	GO:0004888
GeneOntologyMolecularFunction	RNA polymerase II C-terminal domain phosphoserine binding	SCAF8 SCAF4	3.60e-04	5	121	2	GO:1990269
GeneOntologyMolecularFunction	hypotaurine monooxygenase activity	FMO1 FMO2	3.60e-04	5	121	2	GO:0047822
GeneOntologyMolecularFunction	opsonin binding	CFH CR1 CR1L	4.53e-04	25	121	3	GO:0001846
GeneOntologyMolecularFunction	N,N-dimethylaniline monooxygenase activity	FMO1 FMO2	5.38e-04	6	121	2	GO:0004499
GeneOntologyMolecularFunction	opsonin receptor activity	CR1 CR1L	9.96e-04	8	121	2	GO:0001847
GeneOntologyBiologicalProcess	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	SCAF8 SCAF4	3.36e-05	2	120	2	GO:2000805
GeneOntologyBiologicalProcess	negative regulation of termination of RNA polymerase II transcription	SCAF8 SCAF4	3.36e-05	2	120	2	GO:0120191
GeneOntologyBiologicalProcess	regulation of complement-dependent cytotoxicity	CFH CR1 CR1L	5.26e-05	13	120	3	GO:1903659
GeneOntologyBiologicalProcess	negative regulation of termination of DNA-templated transcription	SCAF8 SCAF4	1.00e-04	3	120	2	GO:0060567
GeneOntologyBiologicalProcess	termination of RNA polymerase II transcription, poly(A)-coupled	SCAF8 SCAF4	1.00e-04	3	120	2	GO:0030846
GeneOntologyBiologicalProcess	regulation of termination of RNA polymerase II transcription, poly(A)-coupled	SCAF8 SCAF4	1.00e-04	3	120	2	GO:2000804
GeneOntologyBiologicalProcess	complement-dependent cytotoxicity	CFH CR1 CR1L	1.02e-04	16	120	3	GO:0097278
GeneOntologyBiologicalProcess	complement activation, alternative pathway	CFH CR1 CFB	1.74e-04	19	120	3	GO:0006957
GeneOntologyBiologicalProcess	tumor necrosis factor (ligand) superfamily member 11 production	CCN1 LTF	2.00e-04	4	120	2	GO:0072535
GeneOntologyBiologicalProcess	regulation of termination of RNA polymerase II transcription	SCAF8 SCAF4	2.00e-04	4	120	2	GO:1904594
GeneOntologyBiologicalProcess	regulation of tumor necrosis factor (ligand) superfamily member 11 production	CCN1 LTF	2.00e-04	4	120	2	GO:2000307
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	PSAP GPR37 ADGRB3 CHRM5 ADGRG4 ADGRF5 PSAPL1 ADGRF1	2.72e-04	286	120	8	GO:0007188
GeneOntologyBiologicalProcess	regulation of humoral immune response mediated by circulating immunoglobulin	GIMAP5 CR1 CR1L	2.73e-04	22	120	3	GO:0002923
GeneOntologyBiologicalProcess	response to camptothecin	FANCB SPIDR	3.32e-04	5	120	2	GO:1901563
GeneOntologyBiologicalProcess	cellular response to camptothecin	FANCB SPIDR	3.32e-04	5	120	2	GO:0072757
Domain	CUB	ADGRB3 CDCP1 CSMD3 LRP10 NETO1 TMPRSS7	1.23e-06	53	122	6	PS01180
Domain	CUB_dom	ADGRB3 CDCP1 CSMD3 LRP10 NETO1 TMPRSS7	1.90e-06	57	122	6	IPR000859
Domain	-	CDCP1 CSMD3 LRP10 NETO1 TMPRSS7	2.23e-05	52	122	5	2.60.120.290
Domain	Sushi	CFH CR1 CR1L CSMD3 CFB	2.23e-05	52	122	5	PF00084
Domain	CCP	CFH CR1 CR1L CSMD3 CFB	2.68e-05	54	122	5	SM00032
Domain	SUSHI	CFH CR1 CR1L CSMD3 CFB	3.21e-05	56	122	5	PS50923
Domain	Sushi_SCR_CCP_dom	CFH CR1 CR1L CSMD3 CFB	3.50e-05	57	122	5	IPR000436
Domain	Saposin_chordata	PSAP PSAPL1	4.23e-05	2	122	2	IPR021165
Domain	DUF4685	KIAA1614 C9orf50	4.23e-05	2	122	2	IPR032756
Domain	DUF4685	KIAA1614 C9orf50	4.23e-05	2	122	2	PF15737
Domain	GPS	ADGRB3 ADGRG4 ADGRF5 ADGRF1	6.91e-05	34	122	4	SM00303
Domain	GPS	ADGRB3 ADGRG4 ADGRF5 ADGRF1	7.76e-05	35	122	4	PF01825
Domain	GPS	ADGRB3 ADGRG4 ADGRF5 ADGRF1	8.68e-05	36	122	4	PS50221
Domain	GPS	ADGRB3 ADGRG4 ADGRF5 ADGRF1	9.69e-05	37	122	4	IPR000203
Domain	SapB_1	PSAP PSAPL1	1.26e-04	3	122	2	IPR007856
Domain	SAPA	PSAP PSAPL1	1.26e-04	3	122	2	SM00162
Domain	SapA	PSAP PSAPL1	1.26e-04	3	122	2	PF02199
Domain	SapB_1	PSAP PSAPL1	1.26e-04	3	122	2	PF05184
Domain	Saposin	PSAP PSAPL1	1.26e-04	3	122	2	IPR008373
Domain	SAP_A	PSAP PSAPL1	1.26e-04	3	122	2	PS51110
Domain	SAP_A	PSAP PSAPL1	1.26e-04	3	122	2	IPR003119
Domain	GPCR_2_extracellular_dom	ADGRB3 ADGRG4 ADGRF5 ADGRF1	1.32e-04	40	122	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRB3 ADGRG4 ADGRF5 ADGRF1	1.32e-04	40	122	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB3 ADGRG4 ADGRF5 ADGRF1	1.32e-04	40	122	4	PS50227
Domain	GPCR_2_Ig-hepta-like_rcpt	ADGRF5 ADGRF1	2.52e-04	4	122	2	IPR008078
Domain	CUB	CSMD3 LRP10 NETO1 TMPRSS7	2.93e-04	49	122	4	PF00431
Domain	WD40	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	3.03e-04	259	122	8	PF00400
Domain	7tm_2	ADGRB3 ADGRG4 ADGRF5 ADGRF1	3.16e-04	50	122	4	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB3 ADGRG4 ADGRF5 ADGRF1	3.16e-04	50	122	4	PS00650
Domain	CUB	CSMD3 LRP10 NETO1 TMPRSS7	3.16e-04	50	122	4	SM00042
Domain	-	CORO1C FBXW2 THOC3 PLXNB2 HIRA PIK3R4 CORO6 IFT122 WDR86	3.41e-04	333	122	9	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	CORO1C FBXW2 THOC3 PLXNB2 HIRA PIK3R4 CORO6 IFT122 WDR86	3.56e-04	335	122	9	IPR015943
Domain	WD40	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	3.81e-04	268	122	8	SM00320
Domain	SEA	ADGRF5 TMPRSS7 ADGRF1	3.82e-04	22	122	3	PF01390
Domain	Flavin_mOase	FMO1 FMO2	4.18e-04	5	122	2	IPR000960
Domain	DiMe-aniline_mOase	FMO1 FMO2	4.18e-04	5	122	2	IPR012143
Domain	SapB_2	PSAP PSAPL1	4.18e-04	5	122	2	PF03489
Domain	FMO-like	FMO1 FMO2	4.18e-04	5	122	2	PF00743
Domain	SapB_2	PSAP PSAPL1	4.18e-04	5	122	2	IPR008138
Domain	Flavin_mOase-like	FMO1 FMO2	4.18e-04	5	122	2	IPR020946
Domain	WD40_repeat	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	4.20e-04	272	122	8	IPR001680
Domain	SEA	ADGRF5 TMPRSS7 ADGRF1	4.38e-04	23	122	3	PS50024
Domain	SEA_dom	ADGRF5 TMPRSS7 ADGRF1	4.38e-04	23	122	3	IPR000082
Domain	WD_REPEATS_1	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	4.85e-04	278	122	8	PS00678
Domain	WD_REPEATS_2	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	4.97e-04	279	122	8	PS50082
Domain	WD_REPEATS_REGION	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	4.97e-04	279	122	8	PS50294
Domain	SapB	PSAP PSAPL1	6.24e-04	6	122	2	SM00741
Domain	GPCR_2_secretin-like	ADGRB3 ADGRG4 ADGRF5 ADGRF1	6.37e-04	60	122	4	IPR000832
Domain	GPCR_2-like	ADGRB3 ADGRG4 ADGRF5 ADGRF1	6.37e-04	60	122	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRB3 ADGRG4 ADGRF5 ADGRF1	6.78e-04	61	122	4	PS50261
Domain	WD40_repeat_CS	CORO1C FBXW2 HIRA PIK3R4 CORO6 WDR86	7.31e-04	164	122	6	IPR019775
Domain	WD40_repeat_dom	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	7.48e-04	297	122	8	IPR017986
Domain	RNA_pol_II-bd	SCAF8 SCAF4	8.70e-04	7	122	2	IPR006903
Domain	Arm_3	KPNA5 KPNA1	8.70e-04	7	122	2	PF16186
Domain	CTD_bind	SCAF8 SCAF4	8.70e-04	7	122	2	PF04818
Domain	Importing_su_alpha	KPNA5 KPNA1	8.70e-04	7	122	2	IPR024931
Domain	IBB	KPNA5 KPNA1	8.70e-04	7	122	2	PF01749
Domain	Trimer_CC	CORO1C CORO6	8.70e-04	7	122	2	IPR015049
Domain	DUF1899	CORO1C CORO6	8.70e-04	7	122	2	IPR015048
Domain	Trimer_CC	CORO1C CORO6	8.70e-04	7	122	2	PF08954
Domain	DUF1899	CORO1C CORO6	8.70e-04	7	122	2	PF08953
Domain	Coronin	CORO1C CORO6	8.70e-04	7	122	2	IPR015505
Domain	SaposinB_dom	PSAP PSAPL1	8.70e-04	7	122	2	IPR008139
Domain	Arm_3	KPNA5 KPNA1	8.70e-04	7	122	2	IPR032413
Domain	DUF1899	CORO1C CORO6	8.70e-04	7	122	2	SM01166
Domain	Arm	KPNA5 ODAD2 KPNA1	1.07e-03	31	122	3	PF00514
Domain	RPR	SCAF8 SCAF4	1.15e-03	8	122	2	SM00582
Domain	Saposin-like	PSAP PSAPL1	1.15e-03	8	122	2	IPR011001
Domain	IBB	KPNA5 KPNA1	1.15e-03	8	122	2	PS51214
Domain	CID_dom	SCAF8 SCAF4	1.15e-03	8	122	2	IPR006569
Domain	-	PSAP PSAPL1	1.15e-03	8	122	2	1.10.225.10
Domain	CID	SCAF8 SCAF4	1.15e-03	8	122	2	PS51391
Domain	GPCR_2_secretin-like_CS	ADGRB3 ADGRG4 ADGRF5	1.40e-03	34	122	3	IPR017983
Domain	PENTAXIN	NPTX1 ADGRG4	1.48e-03	9	122	2	PS00289
Domain	Importin-a_IBB	KPNA5 KPNA1	1.48e-03	9	122	2	IPR002652
Domain	SAP_B	PSAP PSAPL1	1.48e-03	9	122	2	PS50015
Domain	DAGK_acc	DGKD DGKH	1.84e-03	10	122	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKD DGKH	1.84e-03	10	122	2	IPR000756
Domain	PTX	NPTX1 ADGRG4	1.84e-03	10	122	2	SM00159
Domain	DAGKa	DGKD DGKH	1.84e-03	10	122	2	SM00045
Domain	ARM-like	KPNA5 HEATR5A ODAD2 PIK3R4 HECTD1 AGBL1 KPNA1	1.99e-03	270	122	7	IPR011989
Domain	Pentaxin-related	NPTX1 ADGRG4	2.24e-03	11	122	2	IPR001759
Domain	Pentaxin	NPTX1 ADGRG4	2.24e-03	11	122	2	PF00354
Domain	LDLR_class-A_CS	LRP10 NETO1 TMPRSS7	2.25e-03	40	122	3	IPR023415
Domain	ARM_REPEAT	KPNA5 ODAD2 KPNA1	2.25e-03	40	122	3	PS50176
Domain	ARM	KPNA5 ODAD2 KPNA1	2.25e-03	40	122	3	SM00185
Domain	SAM_2	STARD13 DGKD DGKH	2.77e-03	43	122	3	PF07647
Domain	Ldl_recept_a	LRP10 NETO1 TMPRSS7	3.16e-03	45	122	3	PF00057
Domain	ConA-like_dom	NPTX1 LAMA2 TRIM43 TRIM65 ADGRG4 TRIM43B	3.18e-03	219	122	6	IPR013320
Domain	-	LRP10 NETO1 TMPRSS7	3.36e-03	46	122	3	4.10.400.10
Domain	-	KPNA5 HEATR5A ODAD2 PIK3R4 HECTD1 KPNA1	3.39e-03	222	122	6	1.25.10.10
Domain	SAM_DOMAIN	STARD13 DGKD DGKH ARAP2	3.49e-03	95	122	4	PS50105
Domain	Armadillo	KPNA5 ODAD2 KPNA1	3.58e-03	47	122	3	IPR000225
Domain	DAGKc	DGKD DGKH	3.66e-03	14	122	2	SM00046
Domain	SAM	STARD13 DGKD DGKH ARAP2	3.76e-03	97	122	4	IPR001660
Domain	LDLRA_1	LRP10 NETO1 TMPRSS7	3.80e-03	48	122	3	PS01209
Domain	LDrepeatLR_classA_rpt	LRP10 NETO1 TMPRSS7	4.02e-03	49	122	3	IPR002172
Domain	LDLa	LRP10 NETO1 TMPRSS7	4.02e-03	49	122	3	SM00192
Domain	LDLRA_2	LRP10 NETO1 TMPRSS7	4.02e-03	49	122	3	PS50068
Domain	Diacylglycerol_kinase_cat_dom	DGKD DGKH	4.20e-03	15	122	2	IPR001206
Pubmed	The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.	CFH CR1 CR1L CFB	8.73e-10	5	128	4	20675597
Pubmed	Circulating AIM prevents hepatocellular carcinoma through complement activation.	CFH CR1 CR1L CD69	3.61e-08	10	128	4	25284781
Pubmed	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.	CR1 CR1L CFB	4.87e-08	3	128	3	20660348
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	CFH CR1 CR1L CFB	5.66e-08	11	128	4	23204401
Pubmed	Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.	CFH CR1 CR1L	1.94e-07	4	128	3	27165610
Pubmed	Membrane protein Crry maintains homeostasis of the complement system.	CR1 CR1L CFB	1.94e-07	4	128	3	18684964
Pubmed	Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack.	CFH CR1 CR1L	4.84e-07	5	128	3	23390291
Pubmed	C3-dependent mechanism of microglial priming relevant to multiple sclerosis.	CFH CR1 CR1L	4.84e-07	5	128	3	22219359
Pubmed	Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement.	CR1 CR1L CFB	4.84e-07	5	128	3	17916747
Pubmed	Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack.	CR1 CR1L CFB	4.84e-07	5	128	3	17015743
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CFH CR1 CR1L	4.84e-07	5	128	3	20962256
Pubmed	The regulation of the complement system: insights from genetically-engineered mice.	CFH CR1 CR1L	1.69e-06	7	128	3	12914820
Pubmed	Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.	CFH CR1 CR1L	1.69e-06	7	128	3	28057640
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRG4 ADGRF5 ADGRF1	2.69e-06	8	128	3	12435584
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CFH CR1 CR1L	2.69e-06	8	128	3	2564419
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	CR1 CR1L CFB	2.69e-06	8	128	3	14670299
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRB3 ADGRG4 ADGRF5 ADGRF1	3.87e-06	29	128	4	15203201
Pubmed	Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.	CFH CR1 CR1L	4.02e-06	9	128	3	18947875
Pubmed	Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.	CFH CR1 CR1L	5.73e-06	10	128	3	8422330
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB3 ADGRG4 ADGRF5 ADGRF1	6.59e-06	33	128	4	25713288
Pubmed	Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.	CR1 CR1L CFB	1.05e-05	12	128	3	18524992
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	GPR22 ADGRB3 ADGRG4 ADGRF5 ADGRF1	1.13e-05	79	128	5	12679517
Pubmed	Functional identification of transcription control sequences of the mouse Crry gene.	CR1 CR1L	1.34e-05	2	128	2	8335915
Pubmed	Complement factor H is expressed in adipose tissue in association with insulin resistance.	CFH CFB	1.34e-05	2	128	2	19833879
Pubmed	Identification and characterization of two splice variants of human diacylglycerol kinase eta.	DGKD DGKH	1.34e-05	2	128	2	12810723
Pubmed	Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.	CR1 CR1L	1.34e-05	2	128	2	10779754
Pubmed	Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.	CR1 CR1L	1.34e-05	2	128	2	17674370
Pubmed	GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability.	PSAP GPR37	1.34e-05	2	128	2	24371137
Pubmed	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.	CR1 CR1L	1.34e-05	2	128	2	16444293
Pubmed	Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.	CR1 CR1L	1.34e-05	2	128	2	1730912
Pubmed	Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.	CR1 CR1L	1.34e-05	2	128	2	19740350
Pubmed	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.	CR1 CR1L	1.34e-05	2	128	2	11698469
Pubmed	Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones.	CR1 CR1L	1.34e-05	2	128	2	34709768
Pubmed	The murine complement regulator Crry: new insights into the immunobiology of complement regulation.	CR1 CR1L	1.34e-05	2	128	2	11915940
Pubmed	Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.	CR1 CR1L	1.34e-05	2	128	2	7691944
Pubmed	The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1.	CR1 CR1L	1.34e-05	2	128	2	2911011
Pubmed	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.	CR1 CR1L	1.34e-05	2	128	2	12902517
Pubmed	Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.	CR1 CR1L	1.34e-05	2	128	2	17015675
Pubmed	SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.	SCAF8 SCAF4	1.34e-05	2	128	2	31104839
Pubmed	Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.	CR1 CR1L	1.34e-05	2	128	2	23153828
Pubmed	Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.	CR1 CR1L	1.34e-05	2	128	2	2952719
Pubmed	Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice.	CR1 CR1L	1.34e-05	2	128	2	12973023
Pubmed	Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.	CR1 CR1L	1.34e-05	2	128	2	10586048
Pubmed	In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.	CR1 CR1L	1.34e-05	2	128	2	16301687
Pubmed	A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo.	CFH CFB	1.34e-05	2	128	2	27241480
Pubmed	Expression dynamics of Crry at the implantation sites in normal pregnancy and response against miscarriage induction.	CR1 CR1L	1.34e-05	2	128	2	36450590
Pubmed	Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes.	CFH CR1	1.34e-05	2	128	2	2977721
Pubmed	Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.	CR1 CR1L	1.34e-05	2	128	2	16301324
Pubmed	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.	CR1 CR1L	1.34e-05	2	128	2	12767833
Pubmed	Association of CFH and CFB gene polymorphisms with retinopathy in type 2 diabetic patients.	CFH CFB	1.34e-05	2	128	2	23864767
Pubmed	The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes.	CR1 CR1L	1.34e-05	2	128	2	2307848
Pubmed	Complement regulatory protein Crry/p65 costimulation expands natural treg cells with enhanced suppressive properties in proteoglycan-induced arthritis.	CR1 CR1L	1.34e-05	2	128	2	21380996
Pubmed	Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.	CR1 CR1L	1.34e-05	2	128	2	20484840
Pubmed	Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.	FMO1 FMO2	1.34e-05	2	128	2	15144220
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GPR37 NPEPPS CORO1C ALDH1L1 THOC3 TGM5 SCAF4 PIK3R4 MTHFD1 WNT10A	1.64e-05	497	128	10	36774506
Pubmed	GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.	PSAP GPR37	4.02e-05	3	128	2	23690594
Pubmed	Duplication and divergence of the amino-terminal coding region of the complement receptor 1 (CR1) gene. An example of concerted (horizontal) evolution within a gene.	CR1 CR1L	4.02e-05	3	128	2	2295627
Pubmed	Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H.	CFH CFB	4.02e-05	3	128	2	12091909
Pubmed	Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infection.	CFH CFB	4.02e-05	3	128	2	17420242
Pubmed	CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.	IFNAR1 CD69	4.02e-05	3	128	2	22250092
Pubmed	Genome-wide scan for copy number variation association with age at onset of Alzheimer's disease.	CR1 CPNE4	4.02e-05	3	128	2	23202439
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CFH CR1	4.02e-05	3	128	2	3782802
Pubmed	Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.	CFH CFB	4.02e-05	3	128	2	23112567
Pubmed	Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a chinese population.	CFH CFB	4.02e-05	3	128	2	19899988
Pubmed	The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance.	FMO1 FMO2	4.02e-05	3	128	2	24792439
Pubmed	Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.	KPNA5 KPNA1	4.02e-05	3	128	2	20406804
Pubmed	Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population.	CFH CFB	4.02e-05	3	128	2	34233521
Pubmed	Genetic control of the alternative pathway of complement in humans and age-related macular degeneration.	CFH CFB	4.02e-05	3	128	2	19825847
Pubmed	Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury.	CR1 CR1L	4.02e-05	3	128	2	24850152
Pubmed	Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.	CR1 CR1L	4.02e-05	3	128	2	11907125
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR1L	4.02e-05	3	128	2	2528587
Pubmed	Small, hard macular drusen and peripheral drusen: associations with AMD genotypes in the Inter99 Eye Study.	CFH CFB	4.02e-05	3	128	2	20007824
Pubmed	Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.	CFH CR1	4.02e-05	3	128	2	20702729
Pubmed	ATM gene variants in patients with idiopathic perifoveal telangiectasia.	CFH CFB	4.02e-05	3	128	2	18502988
Pubmed	Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse.	CFH CFB	4.02e-05	3	128	2	33410734
Pubmed	Complement factor H-deficient mice develop spontaneous hepatic tumors.	CFH CFB	4.02e-05	3	128	2	32369457
Pubmed	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the carboxyl-terminal domain of RNA polymerase II.	SCAF8 SCAF4	4.02e-05	3	128	2	18550522
Pubmed	Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).	CFH CR1	4.02e-05	3	128	2	9988761
Pubmed	Variation in complement factor 3 is associated with risk of age-related macular degeneration.	CFH CFB	4.02e-05	3	128	2	17767156
Pubmed	Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population.	CFH CFB	4.02e-05	3	128	2	19187590
Pubmed	Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk.	CFH CFB	4.02e-05	3	128	2	21555552
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR1L	4.02e-05	3	128	2	7528766
Pubmed	Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method.	DGKD DGKH	4.02e-05	3	128	2	23949095
Pubmed	Inherited Kidney Complement Diseases.	CFH CFB	4.02e-05	3	128	2	33536243
Pubmed	Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein.	KPNA5 KPNA1	4.02e-05	3	128	2	12740372
Pubmed	[Hepatitis B virus X protein upregulates the expression of CD59 and Crry in mouse podocytes].	CR1 CR1L	4.02e-05	3	128	2	21215189
Pubmed	Disruption of the alternative pathway convertase occurs at the staphylococcal surface via the acquisition of factor H by Staphylococcus aureus.	CFH CFB	4.02e-05	3	128	2	21163532
Pubmed	CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs.	IFNAR1 CD69	4.02e-05	3	128	2	16525420
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR1L	4.02e-05	3	128	2	2139460
Pubmed	A critical role for murine complement regulator crry in fetomaternal tolerance.	CR1 CR1L	4.02e-05	3	128	2	10642554
Pubmed	Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.	FMO1 FMO2	4.02e-05	3	128	2	30381441
Pubmed	Gender is an important determinant of the disposition of the loop diuretic torasemide.	SLC22A11 SLCO1B1	4.02e-05	3	128	2	19934028
Pubmed	Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse olfactory organ.	PSAP GPR37	4.02e-05	3	128	2	37075680
Pubmed	Serum Levels of Complement Factors C1q, Bb, and H in Normal Pregnancy and Severe Pre-Eclampsia.	CFH CFB	4.02e-05	3	128	2	31541546
Pubmed	Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome.	CFH CFB	4.02e-05	3	128	2	23356914
Pubmed	Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.	FMO1 FMO2	4.02e-05	3	128	2	19262426
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	CFH TNFRSF9 GIMAP5 GPR37 CR1 LECT2 IFNAR1 CD3D CCN1 CD163L1 CD69 LTF	5.57e-05	824	128	12	20237496
Pubmed	p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.	CR1 CR1L	8.02e-05	4	128	2	19124833
Pubmed	Association between polymorphisms of complement pathway genes and age-related macular degeneration in a Chinese population.	CFH CFB	8.02e-05	4	128	2	23233260
Pubmed	C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.	CFH CFB	8.02e-05	4	128	2	18493315
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH CR1 CR1L CSMD3 CFB	1.10e-05	57	93	5	1179
GeneFamily	Complement system\|Sushi domain containing	CFH CR1 CR1L CFB	3.41e-05	36	93	4	492
GeneFamily	WD repeat domain containing	CORO1C FBXW2 THOC3 HIRA PIK3R4 CORO6 IFT122 WDR86	6.15e-05	262	93	8	362
GeneFamily	Adhesion G protein-coupled receptors, subfamily F	ADGRF5 ADGRF1	2.59e-04	5	93	2	916
GeneFamily	WD repeat domain containing\|Coronins	CORO1C CORO6	5.41e-04	7	93	2	495
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKD DGKH	1.15e-03	10	93	2	1178
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	KPNA5 ODAD2 KPNA1	1.40e-03	43	93	3	409
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IGSF5 DSCAML1 UNC5A ADGRF5 IGSF9B	1.46e-03	161	93	5	593
GeneFamily	Armadillo repeat containing\|Importins	KPNA5 KPNA1	3.80e-03	18	93	2	596
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	TNFRSF9 TNFRSF17 CDCP1 CR1 CD2 CD3D CD69	4.21e-03	394	93	7	471
CoexpressionAtlas	kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#3_top-relative-expression-ranked_200	CFH FMO2 CFB	9.90e-06	8	121	3	gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k3_200
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 TNFRSF9 GIMAP5 CD2 CD3D CD163L1 AGBL1	3.32e-07	156	127	7	0bd32876413f3308f838f266e8c39ea0937ce5b9
ToppCell	Club_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	CFH NPTX1 FMO2 IGSF5 ELAPOR1 WDR86 LTF	4.65e-07	164	127	7	4e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 IGSF5 FCHO1 CD2 CD3D CD163L1 ELAPOR1	6.17e-07	171	127	7	4198e7fef1aaee3d85722094f3e444655d393e9e
ToppCell	facs-Skin-nan-24m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D SACS NETO1 CD163L1 CD69	6.93e-07	174	127	7	6863222bec844f40c0c80f5c82a8ff51d1a56d0a
ToppCell	facs-Skin-nan-24m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D SACS NETO1 CD163L1 CD69	6.93e-07	174	127	7	5739c1b8d643ad360ef32049832d749c530ca603
ToppCell	facs-Skin-nan-24m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D SACS NETO1 CD163L1 CD69	6.93e-07	174	127	7	d570eab215f8287362084e37f35672e20aa0f7a2
ToppCell	facs-Trachea-nan-18m-Lymphocytic\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 CD2 CD3D CD163L1 CD69 C9orf50 ARAP2	7.49e-07	176	127	7	9dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCell	facs-Trachea-nan-18m-Lymphocytic-T_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 CD2 CD3D CD163L1 CD69 C9orf50 ARAP2	7.49e-07	176	127	7	d990e7af8120210100d13caa0465b27cf77a451a
ToppCell	facs-Trachea-nan-18m-Lymphocytic-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 CD2 CD3D CD163L1 CD69 C9orf50 ARAP2	7.49e-07	176	127	7	14c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D SACS CD163L1 CD69	7.78e-07	177	127	7	7853430fb0d1a18d835e8956777e0616c5d7d412
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D SACS CD163L1 CD69	7.78e-07	177	127	7	9a5bf67a801826d094f679dd2189b62296c9694f
ToppCell	facs-Skin-Anagen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D SACS CD163L1 CD69	7.78e-07	177	127	7	395f005f019aabb18738d3a10a04c37f216deda3
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	STARD13 FMO2 ADGRB3 LAMA2 REN NGF ADGRF5	8.39e-07	179	127	7	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	facs-Trachea-18m-Hematologic-lymphocytic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	8.71e-07	180	127	7	c35cf2510183c09688453b12e721d264cf57caad
ToppCell	facs-Trachea-18m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	9.03e-07	181	127	7	a23b2e12bc133166e3ed45ab7116f74afbca6eec
ToppCell	facs-Trachea-18m-Hematologic-lymphocytic-T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	9.03e-07	181	127	7	7875fe64ec500a925245ab50cffd6890eabaea8c
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 FMO2 LAMA2 CFB CCN1 NGF HMGCLL1	9.03e-07	181	127	7	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	facs-GAT-Fat-24m-Lymphocytic\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D CD163L1 CD69 ARAP2	9.72e-07	183	127	7	377c2c6fcb2fd41396dd7a7a90e9d7ccafccf2f0
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TNFRSF9 CEMIP2 CD2 CD3D CEP78 CD69 ARAP2	9.72e-07	183	127	7	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	facs-GAT-Fat-24m-Lymphocytic-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D CD163L1 CD69 ARAP2	9.72e-07	183	127	7	f0a6f4f8563491c83fb991b9fb81e75fec7d1ace
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D CD69 C9orf50 ARAP2	1.01e-06	184	127	7	f9365feed31e48f3382588bab077f99c5a3f5b04
ToppCell	facs-Trachea-24m-Hematologic-lymphocytic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	1.25e-06	190	127	7	10f7d33fd1ff096f8fe5b7b11a58819d6cc14fbc
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.29e-06	191	127	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.34e-06	192	127	7	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISPLD2 FMO2 ADGRB3 LAMA2 ALDH1L1 CORO6 HMGCLL1	1.44e-06	194	127	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFRSF9 GIMAP5 CEMIP2 CD2 CD3D CD69 ARAP2	1.44e-06	194	127	7	13c3674d601c8a7355ce869de1af6401938c0037
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CRISPLD2 FMO1 FMO2 LAMA2 CFB CPNE4	1.44e-06	194	127	7	3d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 GIMAP5 CEMIP2 KANK3 ADGRF5 EMP1 ARAP2	1.44e-06	194	127	7	44c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 DGKH CEMIP2 KRT80 KANK3 ADGRF5 ARAP2	1.44e-06	194	127	7	e30a3765feae5cd10ddba16a166c31eb5717edd3
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNFRSF9 CEMIP2 CD2 CD3D TRAPPC10 CD69 ARAP2	1.49e-06	195	127	7	0a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCell	(1)_T_CD8_activated\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TNFRSF9 GIMAP5 CEMIP2 CD2 CD3D CD69 ARAP2	1.49e-06	195	127	7	2253590339b87692d350f9ea3d2aa851179967e1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.54e-06	196	127	7	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.54e-06	196	127	7	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.64e-06	198	127	7	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.76e-06	200	127	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.76e-06	200	127	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO1 FMO2 LAMA2 CCN1 EMP1	1.76e-06	200	127	7	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO1 FMO2 LAMA2 CCN1 EMP1	1.76e-06	200	127	7	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFH CRISPLD2 FMO2 LAMA2 CFB CCN1 EMP1	1.76e-06	200	127	7	fc3c4778841c4b8bac0afb458352614b2c460617
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH CRISPLD2 FMO1 FMO2 LAMA2 CCN1 EMP1	1.76e-06	200	127	7	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 CCN1 HMGCLL1	1.76e-06	200	127	7	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-T_lymphocytic\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	REN CD2 CD3D CD69 ADGRF1 HECTD1	2.10e-06	131	127	6	1be75b37d87942941f6f46009373d79647107ca9
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	REN CD2 CD3D CD69 ADGRF1 HECTD1	2.10e-06	131	127	6	c84d4c764482353ba226f8707f736260da9dff13
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRMT10B UBAP2 GIMAP5 FANCB CD2 EMP1	3.36e-06	142	127	6	5fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRMT10B UBAP2 GIMAP5 FANCB CD2 EMP1	3.36e-06	142	127	6	16f9945e835c3506b12d904778560d065a50f059
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRMT10B UBAP2 GIMAP5 FANCB CD2 EMP1	3.36e-06	142	127	6	58bfff3284ae21150e4619511bd58622c16c5dde
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 FCHO1 CD2 CD69 LTF TMPRSS7	5.16e-06	153	127	6	a8f83ec640fae51d4fba34b92e3d6cca4999e930
ToppCell	RV-17._Lymphocyte\|RV / Chamber and Cluster_Paper	TDRD15 FCHO1 CD2 CD3D CD69 ARAP2	5.16e-06	153	127	6	e1ea621184014415870e00d511386b8cc3e0833b
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 GIMAP5 IGSF5 CD2 CD69 ARAP2	5.56e-06	155	127	6	93513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 FCHO1 CD2 CD69 LTF TMPRSS7	7.42e-06	163	127	6	66ecd544d7b52e61880b125bf39d1f406af6900a
ToppCell	Influenza_Severe-CD4+_CTL\|Influenza_Severe / Disease group and Cell class	SLC9B1 CD2 CD3D KANK3 CD69 IGSF9B	7.69e-06	164	127	6	9ffd40ae1f39290840bea79fa4e73cb7e009f310
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	DGKH HEATR5A CD2 CD3D CD69 IFT122	8.24e-06	166	127	6	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-6\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	FMO2 TGM5 PPP1R3A EMP1 AGBL1 ENO3	8.52e-06	167	127	6	4a533972a0f40fff82dccf8e64716cb34f75736e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GIMAP5 THOC3 CEMIP2 CD2 CD3D SACS	8.52e-06	167	127	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF17 FCHO1 ZNF786 CD2 SLC35F3 WNT10A	8.82e-06	168	127	6	ce9fae8b295c668b0959d5007a8bcd401d80e258
ToppCell	facs-MAT-Fat-24m-Lymphocytic-T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 GIMAP5 IGSF5 CD3D CD163L1 CD69	8.82e-06	168	127	6	22fa707689e8d6ca5154103b7374007d644d61c3
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	CFH CRISPLD2 FMO2 ADGRB3 LAMA2 EMP1	9.12e-06	169	127	6	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D CD163L1 CD69 C9orf50	9.44e-06	170	127	6	7040f7b1e4d8d26db787449e557371c5d872c95a
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF17 FCHO1 ZNF786 CD2 SLC35F3 WNT10A	9.76e-06	171	127	6	584a095ddcbf78aa29527f84b46b5ad3e2edbaa9
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FMO2 IGSF5 CFB SLC9B1 ADGRF1	1.01e-05	100	127	5	b4e8f3cbb5023d2227f43e683967ec2f848648f1
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPTX1 FMO1 KRT80 C9orf50 ADGRF5 EMP1	1.01e-05	172	127	6	490745024730df6357f6c2b81d7a64e21557c0d5
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 IGSF5 CD2 CD3D CD163L1 CD69	1.01e-05	172	127	6	976d27edd5608616830624907fe050fcd3551865
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 IGSF5 CD2 CD3D CD163L1 CD69	1.01e-05	172	127	6	a3bcf0d432d8fccce50248e8d0c7a4804d69bfee
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 DSCAML1 HIRA MIGA1 WDR86 ENO3	1.08e-05	174	127	6	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69	1.08e-05	174	127	6	773329bb91b97578df138446cf62101dd0dad758
ToppCell	droplet-Liver-Npc-21m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D SLC35F3 EMP1	1.11e-05	175	127	6	046e841811b22c39f80a9752f3223c1906de6f20
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 DSCAML1 HIRA MIGA1 WDR86 ENO3	1.11e-05	175	127	6	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	facs-Marrow-T_cells-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 FMO2 GIMAP5 CD2 CD3D ADGRF5	1.11e-05	175	127	6	d3d574962c0a4a0d64db120320f0d04e11d2c9d8
ToppCell	facs-Marrow-T_cells\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 FMO2 GIMAP5 CD2 CD3D ADGRF5	1.11e-05	175	127	6	4d77fade9ab87b79ac206d074b0e2ef8930c044e
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 GIMAP5 CD2 CD3D CD163L1 CD69	1.11e-05	175	127	6	d82153bdb0c5cca96485d6b0579440f9c9e3abe2
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH CRISPLD2 FMO2 LAMA2 CCN1 EMP1	1.15e-05	176	127	6	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH CRISPLD2 FMO2 LAMA2 CCN1 EMP1	1.15e-05	176	127	6	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2 CD3D CEP78 CD163L1 ELAPOR1 PIMREG	1.15e-05	176	127	6	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KPNA5 FCHO1 CD2 CD3D MTHFD1 CD69	1.19e-05	177	127	6	64b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell	droplet-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D CD163L1 CD69	1.23e-05	178	127	6	e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCell	droplet-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D CD163L1 CD69	1.23e-05	178	127	6	12d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCell	droplet-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 TNFRSF9 CD2 CD3D CD163L1 CD69	1.23e-05	178	127	6	11c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_large-bowel / Manually curated celltypes from each tissue	CFH GIMAP5 CHRM5 CD2 CD3D CD69	1.27e-05	179	127	6	6359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCell	normal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T\|normal_Lymph_Node / Location, Cell class and cell subclass	TNFRSF9 TGM5 CEMIP2 CD2 CD3D CD69	1.27e-05	179	127	6	3dc929a10381b7d86650c6cd8f354892fe1d93e7
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D CD69 AGBL1	1.31e-05	180	127	6	86cdb1652f1736c38b501f07cf40ce99134cf597
ToppCell	facs-MAT-Fat-24m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	1.31e-05	180	127	6	f3f7a610db750fcb84d746a5ea0d8b57f9b7d901
ToppCell	facs-SCAT-Fat-24m-Lymphocytic\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 FCHO1 CD2 CD3D CD69 AGBL1	1.31e-05	180	127	6	115ce9f048f933704a19759948dcc933245e63c4
ToppCell	facs-MAT-Fat-24m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 CD2 CD3D CD163L1 CD69 ARAP2	1.31e-05	180	127	6	bb2f1b254371924b2045e9e1a81b6dbf4f00dd6a
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 CEMIP2 UNC5A MIGA1 ADGRF5 IFT122	1.35e-05	181	127	6	2c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 GPR22 CFB CCN1 EMP1 ZMYND12	1.35e-05	181	127	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 GPR22 CFB CCN1 EMP1 ZMYND12	1.35e-05	181	127	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 CFH CRISPLD2 FMO2 PPP1R3A CCN1	1.39e-05	182	127	6	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 CFH CRISPLD2 FMO2 PPP1R3A CCN1	1.39e-05	182	127	6	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	TNFRSF9 GIMAP5 LAMA2 CD3D CD69 PIMREG	1.39e-05	182	127	6	dab2ea0298e26649a923c34d4699e437e9385b90
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D CD69 ENO3 ARAP2	1.43e-05	183	127	6	a0a3e4d07ac73dbbb1e019fd11e88ccffe6cf2ca
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFH CEMIP2 FANCB CD2 CD3D CEP78	1.43e-05	183	127	6	90c66ffd2c1f87c91f9a9886e28aeec542f9df85
ToppCell	droplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 IGSF5 CD2 CD3D CD163L1 CD69	1.43e-05	183	127	6	ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCell	PND14\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMO1 GIMAP5 CD2 CD3D CD69 ADGRF5	1.48e-05	184	127	6	1bfee4eb121e76a79f48b06b45f05d124fbbedba
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	TNFRSF9 DGKH DSCAML1 TAFA2 CD2 CD3D	1.48e-05	184	127	6	22c15ce30171c687ab564f4383ae74d38b759272
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D ELAPOR1 CD69 ARAP2	1.53e-05	185	127	6	212a8f6fb9eac0c6a89a20a9aa30d48c21abd375
ToppCell	droplet-Lung-nan-21m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 GIMAP5 CD2 CD3D KANK3 ADGRF5	1.53e-05	185	127	6	43b7345a61e31099718c9cecf194b4e9884b904b
ToppCell	droplet-Lung-21m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO1 GIMAP5 CD2 CD3D KANK3 ADGRF5	1.53e-05	185	127	6	9c907298166e3dd65b1d1e7673a1b8d01b492bd0
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKD CD2 CD3D LRP10 CD69 ARAP2	1.53e-05	185	127	6	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKD CD2 CD3D LRP10 CD69 ARAP2	1.53e-05	185	127	6	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 CD2 CD3D CD69 ENO3 ARAP2	1.57e-05	186	127	6	11929e36d8c9b4c4bc2f5e912f139f474f91ab00
Disease	nucleoside diphosphate kinase A measurement	CFH LTF	1.67e-05	2	121	2	EFO_0009947
Disease	myc target protein 1 measurement	CFH LTF	1.67e-05	2	121	2	EFO_0801812
Disease	cysteine and glycine-rich protein 2 measurement	CFH CFB	4.99e-05	3	121	2	EFO_0802444
Disease	complement C3D fragment measurement	CFH CFB	4.99e-05	3	121	2	EFO_0020277
Disease	glucose-6-phosphate isomerase measurement	CFH CD163L1	4.99e-05	3	121	2	EFO_0020407
Disease	syndrome (implicated_via_orthology)	SCAF8 NSD1 SCAF4	5.25e-05	18	121	3	DOID:225 (implicated_via_orthology)
Disease	lipid storage disease (implicated_via_orthology)	PSAP PSAPL1	9.95e-05	4	121	2	DOID:9455 (implicated_via_orthology)
Disease	sorting nexin-7 measurement	CFH CFB	9.95e-05	4	121	2	EFO_0803094
Disease	portal hypertension (is_implicated_in)	GIMAP5 REN	1.65e-04	5	121	2	DOID:10762 (is_implicated_in)
Disease	interleukin-10 receptor subunit beta measurement	CFH CFB	1.65e-04	5	121	2	EFO_0020489
Disease	thymidine kinase, cytosolic measurement	CFH CFB	2.47e-04	6	121	2	EFO_0020773
Disease	BAG family molecular chaperone regulator 4 measurement	CFH SLCO1B1	2.47e-04	6	121	2	EFO_0802303
Disease	NKG2-E type II integral membrane protein measurement	CFH CFB	2.47e-04	6	121	2	EFO_0801842
Disease	aurora kinase B measurement	CFH CFB	2.47e-04	6	121	2	EFO_0020169
Disease	transmembrane protein 2 measurement	CFH CEMIP2	2.47e-04	6	121	2	EFO_0802155
Disease	transcription factor AP-1 measurement	CFH CFB	2.47e-04	6	121	2	EFO_0021909
Disease	CCAAT/enhancer-binding protein beta measurement	CFH CFB	2.47e-04	6	121	2	EFO_0021905
Disease	DNA-binding protein SATB2 measurement	CFH CFB	2.47e-04	6	121	2	EFO_0802484
Disease	blood sedimentation	CR1 CR1L	3.46e-04	7	121	2	EFO_0004304
Disease	mast/stem cell growth factor receptor kit measurement	CFH CFB	3.46e-04	7	121	2	EFO_0020554
Disease	Glomerulonephritis, Membranoproliferative	CFH CFB	3.46e-04	7	121	2	C0017662
Disease	anterior uveitis (is_implicated_in)	CFH CFB	4.59e-04	8	121	2	DOID:1407 (is_implicated_in)
Disease	PH and SEC7 domain-containing protein 1 measurement	CFH CFB	4.59e-04	8	121	2	EFO_0803302
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFB	4.59e-04	8	121	2	DOID:0080301 (is_implicated_in)
Disease	complement C1q and tumor necrosis factor-related protein 9A measurement	CFH CFB	5.89e-04	9	121	2	EFO_0803293
Disease	Mental deterioration	CR1 TAFA2	5.89e-04	9	121	2	C0234985
Disease	Mild cognitive disorder	CR1 TAFA2	5.89e-04	9	121	2	C1270972
Disease	C3 glomerulopathy	CFH CFB	5.89e-04	9	121	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	CFH CFB	5.89e-04	9	121	2	cv:C2931788
Disease	Hemolytic-uremic syndrome	CFH CFB	5.89e-04	9	121	2	cv:C0019061
Disease	complement factor B measurement	CFH CFB	5.89e-04	9	121	2	EFO_0008096
Disease	interferon alpha/beta receptor 1 measurement	CFH IFNAR1	5.89e-04	9	121	2	EFO_0021850
Disease	tumor necrosis factor ligand superfamily member 14 measurement	CFH CFB	5.89e-04	9	121	2	EFO_0010613
Disease	primary immunodeficiency disease (is_implicated_in)	TNFRSF9 FCHO1 IFNAR1	6.87e-04	42	121	3	DOID:612 (is_implicated_in)
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFB	7.35e-04	10	121	2	C2931788
Disease	octadecanedioate measurement	LAMA2 SLCO1B1	7.35e-04	10	121	2	EFO_0021056
Disease	interleukin-37 measurement	CFH CFB	7.35e-04	10	121	2	EFO_0020506
Disease	creatinine measurement	CFH SCAF8 NSD1 LAMA2 DGKH ALDH1L1 PLXNB2 KIAA1614 PPP1R3A SLC9B1 SLC35F3 CCN1	8.15e-04	995	121	12	EFO_0004518
Disease	response to statin, myopathy	CDCP1 SLCO1B1	8.95e-04	11	121	2	EFO_0004145, GO_0036273
Disease	Methionine sulfoxide measurement	FMO1 FMO2	1.07e-03	12	121	2	EFO_0021650
Disease	brain aneurysm	STARD13 SLC35F3 CD163L1 CPNE4	1.23e-03	113	121	4	EFO_0003870
Disease	MAP kinase-activated protein kinase 3 measurement	CFH ZC3H13	1.26e-03	13	121	2	EFO_0008226
Disease	wet macular degeneration	CFH CFB	1.47e-03	14	121	2	EFO_0004683
Disease	Impaired cognition	CR1 TAFA2	1.47e-03	14	121	2	C0338656
Disease	response to statin	TDRD15 ADGRB3 SLCO1B1	1.59e-03	56	121	3	GO_0036273
Disease	response to statin, LDL cholesterol change measurement	TDRD15 SLCO1B1	1.69e-03	15	121	2	EFO_0007804, GO_0036273
Disease	lysosomal storage disease (implicated_via_orthology)	PSAP PSAPL1	1.93e-03	16	121	2	DOID:3211 (implicated_via_orthology)
Disease	Age-related macular degeneration	CFH CFB	2.44e-03	18	121	2	cv:C0242383
Disease	non-high density lipoprotein cholesterol measurement	TDRD15 DIP2B NPEPPS NSD1 HEATR5A CFB SCAF4 CD163L1 MTARC1	2.73e-03	713	121	9	EFO_0005689
Disease	cerebellum white matter volume change measurement, age at assessment	ADGRB3 DGKH	3.02e-03	20	121	2	EFO_0008007, EFO_0021498
Disease	Liver diseases	CRISPLD2 CD3D ENO3	3.26e-03	72	121	3	C0023895
Disease	Liver Dysfunction	CRISPLD2 CD3D ENO3	3.26e-03	72	121	3	C0086565
Disease	Nephritis, Tubulointerstitial	REN NGF	3.33e-03	21	121	2	C0041349

Protein segments in the cluster

Peptide	Gene	Start	Entry
ECISFQSKKTGINWT	AGBL3	796	Q8NEM8
NCNTSITWVEGTVGT	CD3D	36	P04234
SCWDCAGLSTQKTQG	C9orf50	341	Q5SZB4
SKELTTAVCQSDGTW	CSMD3	2666	Q7Z407
SQSVNFCERTKIWGT	ADGRF1	141	Q5T601
INSWLSSFQKVGVCI	ADGRG4	2796	Q8IZF6
LGTWSTQGCKTVLTD	ADGRB3	831	O60242
FWVNISNCSPTSGKQ	CDCP1	636	Q9H5V8
VQTTSWSQCSKTCGT	CCN1	231	O00622
WTTSLSAKFKCTAGN	CD2	176	P06729
NNWLVKKSSIGCSTN	CMTR2	416	Q8IYT2
SWNRNGSLICTASKD	CORO1C	181	Q9ULV4
AKIFTVLSGNSVWLC	ARAP2	601	Q8WZ64
ITLKTVNFTGCNLTW	CEP78	176	Q5JTW2
ATRGNTAKCTSTGWI	CFH	301	P08603
GWNTTASTVVCKQLG	CD163L1	76	Q9NR16
IKETLWQAACTVGTS	AGBL1	916	Q96MI9
RKEACWTVSNITAGN	KPNA5	356	O15131
TTSETQKSVQCGTWT	NETO1	31	Q8TDF5
AQSCWSAGSTQTLAQ	NSD1	2646	Q96L73
TCSTKALSGNVIAWA	NPTX1	396	Q15818
CRSTGSWSTLKTQDQ	CFB	76	P00751
TVKRSWTSAQNACSE	CD69	101	Q07108
QTLIWLSSQQKTSGC	OVOS1	876	Q6IE37
SAHWQCGATLTQVSV	FCHO1	756	O14526
SNTVDASVGLWKNCT	EMP1	31	P54849
ASVGLWKNCTNISCS	EMP1	36	P54849
IWTQKGNISLFACAT	OR10AG1	76	Q8NH19
AKKCGITVSQVSNWF	PBX2	281	P40425
SSSKIICCSWTNDGQ	IFT122	131	Q9HBG6
NCTWLILGSKEQTVT	LRP10	56	Q7Z4F1
CGEATAQWITSFLKS	MTARC1	161	Q5VT66
CDSVSVWVGDKTTAT	NGF	136	P01138
SAAESTGNCTSSKWV	ELAPOR1	146	Q6UXG2
LTGCWSAGTISKVTV	KRT80	46	Q6KB66
VAKQGVSPCSASQEW	KIAA1614	96	Q5VZ46
SENGRDWKSCVTSIN	BEND2	741	Q8NDZ0
DWKSCVTSINSGIRS	BEND2	746	Q8NDZ0
SSVCSSAVNDPWKSG	CCDC195	91	A0A1B0GUA6
DNWIKLSGCQNITST	IFNAR1	71	P17181
LWSRSKSCVAVTSAQ	PLXNB2	511	O15031
WAAGAAQKATICLVT	MINDY4B	196	A8MYZ0
LTDHKTISVWGCVTQ	OR4L1	86	Q8NH43
VWATTNKIGCAVNTC	CRISPLD2	166	Q9H0B8
SALQRWGTTQAKCSC	DIP2B	341	Q9P265
WANICAGKSSNEIRT	LECT2	21	O14960
TTTQCSEAKGLIRTW	LAMA2	1171	P24043
KNSCSSSRQWVALVV	NPEPPSL1	336	A6NEC2
TLIWLSSQQKTSGCF	OVOS2	1051	Q6IE36
VSQRIQESCQSGTKW	PIMREG	96	Q9BSJ6
ATNNCKWTTLASIGK	DGKH	221	Q86XP1
CTTGQSKVAAWLQDS	OSBPL6	241	Q9BZF3
KCGTGNITSVEESSW	PPP1R3A	836	Q16821
VSFISNNACAVWKES	FANCB	301	Q8NB91
SVTRTCQVKTGTWNG	GIMAP5	61	Q96F15
TTQSWSSLVKNNCPD	HECTD1	1356	Q9ULT8
TPQSNGTLTCVATWK	IGSF5	206	Q9NSI5
AKACQVCSAWIASGV	HEATR5A	1336	Q86XA9
CSSTTAKLAVIWVGA	GPR37	376	O15354
TTCLVSGNNVTWDKK	CR1	1496	P17927
SQWTLTKCQASTPAR	DSCAML1	1746	Q8TD84
TCIISGNTVIWDNKT	CR1L	136	Q2VPA4
AWKSFKVSVNSLCSG	CPNE4	206	Q96A23
CSVTKCSDSAVSGQW	FMO1	111	Q01740
VSKWNAVICSGTYAQ	CEMIP2	981	Q9UHN6
VCWNSNGSLLATTCK	CORO6	181	Q6QEF8
TTQQKLAGVTALSCW	LYPLA1	131	O75608
AVRATNNCKWTTLAS	DGKD	206	Q16760
GSLWCSVTSVFDEKQ	ELSPBP1	96	Q96BH3
CPDFSSSGQWKVVTQ	FMO2	116	Q99518
TTQTPWSCAEKAAQT	KANK3	401	Q6NY19
TESIQACKLAQSNGW	ENO3	351	P13929
SSGKLANVEQWRCVS	HIRA	111	P54198
SGNTWENKTLLCVST	GPR22	186	Q99680
KVWALSAGTCLNTLT	FBXW2	251	Q9UKT8
STIVAKWDLVCSSQG	SLC22A11	126	Q9NSA0
ETASVCSTTLWVGQL	SCAF4	501	O95104
TLSVCSTTLWVGQVD	SCAF8	471	Q9UPN6
DAQKTSWLVCNSVGG	SACS	386	Q9NZJ4
KNSCSSSRQWVALVV	NPEPPS	336	P55786
LWNNATVTTCHSKTA	MTHFD1	186	P11586
CRWNDNSVVTVASSG	PGBD3	411	Q8N328
INSATAWRKAFGTCS	OR2H1	226	Q9GZK4
KETAVASSCWSVLKQ	MIGA1	501	Q8NAN2
SLAGTVACIHWETSQ	HMGCLL1	56	Q8TB92
VGNAKATVSAATATW	RUSF1	121	Q96GQ5
WSCSSGNKVKTTRVT	TAFA2	116	Q8N3H0
KGWVTCSSTDNTDLA	STARD13	926	Q9Y3M8
SLWQFLSSEKQICGT	TRIM43	81	Q96BQ3
CAKGSTVWCQDLQTA	PSAPL1	26	Q6NUJ1
KCNQWSGLSEGSVTC	LTF	376	P02788
VSSCTIKSFTWVQFQ	TDRD15	1716	B5MCY1
ITHCAGSWAQSVLTQ	IGLV1-36	11	A0A0B4J1U3
KEACWTISNITAGNR	KPNA1	356	P52294
TGAIWKCSISKENVT	ODAD2	736	Q5T2S8
GSSNVWVPSSKCSRL	REN	106	P00797
AVVLCVCSSWAGSTQ	SLC35F3	71	Q8IY50
VCSSWAGSTQLAKLT	SLC35F3	76	Q8IY50
FGALIDTTCIKWSTN	SLCO1B1	591	Q9Y6L6
DTTCIKWSTNNCGTR	SLCO1B1	596	Q9Y6L6
SANWAKAEQLTTCSS	CHRM5	291	P08912
IVKATSNTISQCGWS	HTR3D	141	Q70Z44
FNASSVSWCSKTVDV	ADGRF5	626	Q8IZF2
SWKTAACLAAGNTVV	ALDH1L1	581	O75891
ASVSGCVINTCGWVK	CLP1	221	Q92989
SLFATCSNDGTVKIW	PIK3R4	1006	Q99570
DSTSTDVCGTKLVVW	UBAP2	201	Q5T6F2
QRKWTLSGSQQTGCV	nan	6	Q8N2B8
NWSNSTCLKLAVSGG	TRPM6	701	Q9BX84
CTWKFQTSLSTLGIA	TMPRSS7	396	Q7RTY8
WECVATNVVTSITAS	IGSF9B	486	Q9UPX0
QVVCSGVATTGTAWT	SPIDR	431	Q14159
CLKASDTWASGIRSQ	WASH4P	6	A8MWX3
WTNCSLDGKSVLVNG	TNFRSF9	136	Q07011
ATVNTKGENINICWS	THOC3	136	Q96J01
CTLVLSFIAGTKWSQ	SLC9B1	346	Q4ZJI4
TRGSAVWCQNVKTAS	PSAP	26	P07602
VWCQNVKTASDCGAV	PSAP	31	P07602
TGSVAILKQWNATGC	TGM5	256	O43548
CVAWSSSGTTKSQKA	UNC5A	126	Q6ZN44
ACTQTALLQKLTWAS	ZNRD2	151	O60232
AQWTVLKSTDCSNAT	ZMYND12	156	Q9H0C1
QRTITGWSAFESNKC	ZNF658	316	Q5TYW1
WRESQKSGNIICSSV	ZNF786	71	Q8N393
SLWQFLSSEKQICGT	TRIM43B	81	A6NCK2
WATCQTGESTSHVKK	ERVK-19	681	Q9WJR5
GTSGSCQLKTCWQVT	WNT10A	266	Q9GZT5
VVDNSSNWAVCGKSC	TRAPPC10	1116	P48553
EILATGSTAWCSKNV	TRMT10B	51	Q6PF06
WKIQTGETAQVCTKS	ZNF623	86	O75123
NSACILASWVSGKFS	TRIM65	171	Q6PJ69
TNSVKGTNAILWTCL	TNFRSF17	46	Q02223
TCSVWVEKDGVNSSV	PTPRH	96	Q9HD43
TDGTAKVWQVASGCC	WDR86	171	Q86TI4
STAETQCRNWLKTGN	ZC3H13	36	Q5T200
LQKGSTCITNTEGWV	ZSWIM4	396	Q9H7M6
CKAFNWSSALTTLTQ	ZNF257	406	Q9Y2Q1