Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-sulfur bonds	AHCYL1 AHCYL2	2.15e-05	3	54	2	GO:0046508
GeneOntologyMolecularFunction	adenosylhomocysteinase activity	AHCYL1 AHCYL2	2.15e-05	3	54	2	GO:0004013
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC17 MUC3A	4.29e-05	4	54	2	GO:0030197
GeneOntologyMolecularFunction	transcription coregulator binding	CCNT2 HNF1A PER1 NR1D1	5.58e-04	140	54	4	GO:0001221
GeneOntologyMolecularFunction	transcription factor binding	CCNT2 SETD1A HNF1A MTOR RBPJ PER1 DDX20 NR1D1	8.83e-04	753	54	8	GO:0008134
Domain	S-Ado-L-homoCys_hydrolase_CS	AHCYL1 AHCYL2	2.46e-05	3	54	2	IPR020082
Domain	AdoHcyase_NAD	AHCYL1 AHCYL2	2.46e-05	3	54	2	SM00997
Domain	AdoHcyase	AHCYL1 AHCYL2	2.46e-05	3	54	2	SM00996
Domain	AdoHcyase_NAD	AHCYL1 AHCYL2	2.46e-05	3	54	2	PF00670
Domain	ADOHCYASE_1	AHCYL1 AHCYL2	2.46e-05	3	54	2	PS00738
Domain	ADOHCYASE_2	AHCYL1 AHCYL2	2.46e-05	3	54	2	PS00739
Domain	AdoHcyase	AHCYL1 AHCYL2	2.46e-05	3	54	2	PF05221
Domain	Adenosylhomocysteinase	AHCYL1 AHCYL2	2.46e-05	3	54	2	IPR000043
Domain	Ado_hCys_hydrolase_NAD-bd	AHCYL1 AHCYL2	2.46e-05	3	54	2	IPR015878
Domain	SEA	MUC17 MUC3A	7.30e-04	14	54	2	SM00200
Domain	SEA	MUC17 MUC3A	2.00e-03	23	54	2	PS50024
Domain	SEA_dom	MUC17 MUC3A	2.00e-03	23	54	2	IPR000082
Domain	EGF_3	HEG1 MUC17 NRG2 MUC3A	4.72e-03	235	54	4	PS50026
Domain	EGF	HEG1 MUC17 NRG2 MUC3A	4.72e-03	235	54	4	SM00181
Domain	EGF-like_dom	HEG1 MUC17 NRG2 MUC3A	5.79e-03	249	54	4	IPR000742
Domain	EGF_1	HEG1 MUC17 NRG2 MUC3A	6.29e-03	255	54	4	PS00022
Domain	EGF-like_CS	HEG1 MUC17 NRG2 MUC3A	6.82e-03	261	54	4	IPR013032
Domain	EGF_2	HEG1 MUC17 NRG2 MUC3A	7.19e-03	265	54	4	PS01186
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC17 MUC3A MUC5AC	1.65e-05	16	45	3	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC17 MUC3A MUC5AC	2.00e-05	17	45	3	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC17 MUC3A MUC5AC	5.15e-05	23	45	3	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC17 MUC3A MUC5AC	7.51e-05	26	45	3	M27483
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP DOCK4 USP31 MTOR PRRC2C PAK5 NCKIPSD AGFG1 NAV1 CGNL1 WNK1 ARHGAP21 CFAP97 ITPKB	4.97e-11	861	55	14	36931259
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 RBBP6 PRRC2C RBPJ AGFG1 NAV1 DDX20 CGNL1 WNK1 EMSY	2.61e-08	588	55	10	38580884
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK4 USP31 UBAP2L PRRC2C VPS8 NAV1 AHCYL2 ARHGAP21	2.47e-07	407	55	8	12693553
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	AHCYL1 UBAP2L MTOR RBPJ NCKIPSD PER1 AGFG1 AHCYL2 WNK1 ARHGAP21 BEGAIN	5.71e-07	1038	55	11	26673895
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK4 FRMD4A AHCYL1 DSG1 UBAP2L PRRC2C PER1 NAV1 PLPPR3 AHCYL2 BEGAIN	1.41e-06	1139	55	11	36417873
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DSG1 RBBP6 UBAP2L PRRC2C AGFG1 CGNL1 PRPF8 WNK1 ARHGAP21 EMSY	1.82e-06	934	55	10	33916271
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP10 UBAP2L MTOR PRRC2C PAK5 NAV1 ARHGAP21 EMSY GOLGA3 BEGAIN	2.39e-06	963	55	10	28671696
Pubmed	Primers on molecular pathways: bicarbonate transport by the pancreas.	AHCYL1 WNK1	2.46e-06	2	55	2	21242704
Pubmed	REV-ERBα alters circadian rhythms by modulating mTOR signaling.	MTOR NR1D1	2.46e-06	2	55	2	33285244
Pubmed	The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma.	HNF1A MUC5AC	2.46e-06	2	55	2	21348892
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC17 MUC3A MUC5AC	3.00e-06	18	55	3	18834073
Pubmed	High amplitude phase resetting in rev-erbalpha/per1 double mutant mice.	PER1 NR1D1	7.36e-06	3	55	2	20824053
Pubmed	Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.	MUC3A MUC5AC	7.36e-06	3	55	2	18163520
Pubmed	Potassium acts through mTOR to regulate its own secretion.	MTOR WNK1	7.36e-06	3	55	2	31013253
Pubmed	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.	MUC17 MUC3A	7.36e-06	3	55	2	10512748
Pubmed	An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.	AHCYL1 AHCYL2	7.36e-06	3	55	2	19220705
Pubmed	A human MAP kinase interactome.	RBBP6 PAK5 AGFG1 NAV1 NCKAP5 CGNL1 WNK1	1.13e-05	486	55	7	20936779
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	USP31 AHCYL1 KRT16 UBAP2L PRRC2C NCKIPSD NAV1 CGNL1 ARHGAP21 GOLGA3 ITPKB	1.24e-05	1431	55	11	37142655
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CCNT2 AHCYL1 DSG1 RBBP6 UBAP2L NAV1 AHCYL2 PRPF8	1.30e-05	695	55	8	23602568
Pubmed	Circadian regulation of mammalian target of rapamycin signaling in the mouse suprachiasmatic nucleus.	MTOR PER1	1.47e-05	4	55	2	21382453
Pubmed	Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder.	PER1 NR1D1	1.47e-05	4	55	2	30195196
Pubmed	Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor.	HNF1A GOLGA3	1.47e-05	4	55	2	8639776
Pubmed	Childhood cancer mutagenesis caused by transposase-derived PGBD5.	PTCH1 PGBD5	1.47e-05	4	55	2	38517960
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP31 HEG1 PAK5 NAV1	2.20e-05	103	55	4	10574462
Pubmed	Klf15 orchestrates circadian nitrogen homeostasis.	PER1 NR1D1	2.45e-05	5	55	2	22405069
Pubmed	Genetic associations with C-reactive protein level and white blood cell count in the KARE study.	DOCK4 HNF1A	2.45e-05	5	55	2	22788528
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	RANBP10 DSG1 UBAP2L PRRC2C DDX20 PRPF8 GOLGA3	2.53e-05	551	55	7	34728620
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	FRMD4A PER1 EXOC7 PRPF8 ARHGAP21 TTLL7	2.64e-05	371	55	6	15747579
Pubmed	The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator.	PER1 NR1D1	3.67e-05	6	55	2	12150932
Pubmed	The trophoblast clock controls transport across placenta in mice.	PER1 NR1D1	5.13e-05	7	55	2	33913482
Pubmed	Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.	RBPJ PTCH1	5.13e-05	7	55	2	29395868
Pubmed	GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.	HNF1A MUC5AC	5.13e-05	7	55	2	22554936
Pubmed	Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.	DOCK4 AHCYL2	5.13e-05	7	55	2	22890011
Pubmed	Differential expression of the circadian clock in maternal and embryonic tissues of mice.	PER1 NR1D1	5.13e-05	7	55	2	20352049
Pubmed	Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity.	HNF1A NR1D1	5.13e-05	7	55	2	30555544
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 SETD1A HEG1 MTOR PER1 NAV1 PTCH1 WNK1 ARHGAP21	5.46e-05	1105	55	9	35748872
Pubmed	Machine learning helps identify CHRONO as a circadian clock component.	PER1 NR1D1	6.83e-05	8	55	2	24737000
Pubmed	Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.	RBPJ PTCH1	6.83e-05	8	55	2	20418906
Pubmed	Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity.	RBPJ PTCH1	6.83e-05	8	55	2	19124651
Pubmed	IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.	AHCYL1 WNK1	6.83e-05	8	55	2	21317537
Pubmed	Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.	AHCYL1 AHCYL2	8.78e-05	9	55	2	19224921
Pubmed	The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors.	PER1 NR1D1	8.78e-05	9	55	2	20159955
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	KRT16 PRRC2C NCKIPSD AGFG1 WNK1	1.09e-04	298	55	5	30737378
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBBP6 UBAP2L DDX20 EXOC7 WNK1 BEGAIN	1.41e-04	503	55	6	16964243
Pubmed	Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.	MTOR WNK1	1.60e-04	12	55	2	27782176
Pubmed	Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.	PER1 NR1D1	1.60e-04	12	55	2	14645221
Pubmed	RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer.	RBPJ PTCH1	1.60e-04	12	55	2	20950430
Pubmed	A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.	RBPJ PTCH1	1.89e-04	13	55	2	25995356
Pubmed	Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.	PER1 NR1D1	1.89e-04	13	55	2	18228528
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RANBP10 MTOR IFFO1 NAV1 DDX20 EXOC7 PRPF8 WNK1 MUC5AC	2.11e-04	1321	55	9	27173435
Pubmed	Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.	RBPJ MUC5AC	2.21e-04	14	55	2	22797898
Pubmed	Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.	MTOR BRWD1	2.21e-04	14	55	2	28878358
Pubmed	Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.	KRT16 DSG1	2.21e-04	14	55	2	27551807
Pubmed	TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer.	MTOR EXOC7	2.21e-04	14	55	2	28716898
Pubmed	Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.	HNF1A PER1 NR1D1	2.24e-04	74	55	3	26332085
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	RBBP6 MTOR RBPJ PTCH1 PRPF8	2.56e-04	358	55	5	32460013
Pubmed	GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.	PTCH1 MUC5AC	2.90e-04	16	55	2	26932670
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	GOLGA3 BRWD1	2.90e-04	16	55	2	29878059
Pubmed	PER2 variantion is associated with depression vulnerability.	PER1 NR1D1	2.90e-04	16	55	2	19693801
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	UBAP2L MTOR PRRC2C PRPF8	2.99e-04	202	55	4	33005030
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	KRT16 DSG1 PRPF8	3.26e-04	84	55	3	29563501
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	KRT16 DSG1 UBAP2L PRRC2C NAV1 DDX20 AHCYL2 PRPF8 WNK1	3.50e-04	1415	55	9	28515276
Pubmed	Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.	PTCH1 MUC5AC	3.70e-04	18	55	2	36057966
Pubmed	Analysis of the mTOR Interactome using SILAC technology revealed NICE-4 as a novel regulator of mTORC1 activity.	UBAP2L MTOR	3.70e-04	18	55	2	34171383
Pubmed	Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.	PER1 NR1D1	3.70e-04	18	55	2	20174623
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	CCNT2 FRMD4A DSG1 PRPF8 GOLGA3	3.79e-04	390	55	5	17643375
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 IFFO1 CGNL1 ARHGAP21 EMSY CFAP97 BRWD1	3.80e-04	853	55	7	28718761
Pubmed	Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway.	PTCH1 MUC5AC	4.13e-04	19	55	2	27122169
Pubmed	Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.	MTOR RBPJ	4.13e-04	19	55	2	27246713
Pubmed	Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder.	PER1 NR1D1	4.13e-04	19	55	2	20072116
Pubmed	RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.	RBPJ PTCH1	4.13e-04	19	55	2	20335360
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	SETD1A DSG1 UBAP2L PRRC2C DDX20 PRPF8	4.48e-04	624	55	6	33729478
Pubmed	PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.	NCKIPSD NAV1	4.58e-04	20	55	2	32079660
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1A ASXL3	4.58e-04	20	55	2	29785026
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	DDX20 EXOC7 PRPF8 ARHGAP21 GOLGA3	4.66e-04	408	55	5	33766124
Pubmed	Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.	MTOR MUC5AC	5.06e-04	21	55	2	19710174
Pubmed	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.	DDX20 GOLGA3	5.06e-04	21	55	2	24923560
Pubmed	Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia.	PER1 NR1D1	5.06e-04	21	55	2	19839995
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	KRT16 DSG1 UBAP2L PRRC2C DDX20 PRPF8	5.16e-04	641	55	6	36057605
Pubmed	Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.	PTCH1 MUC5AC	5.56e-04	22	55	2	20430747
Pubmed	Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.	MTOR PTCH1	5.56e-04	22	55	2	29725084
Pubmed	Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis.	HNF1A PTCH1	5.56e-04	22	55	2	19737917
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK4 CCNT2 AHCYL1 DSG1 UBAP2L AHCYL2 ARHGAP21	5.80e-04	916	55	7	32203420
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	UBAP2L MTOR DDX20 EXOC7 PRPF8 GOLGA3	5.87e-04	657	55	6	36180527
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A RBBP6 AGFG1 PTCH1 WNK1	5.91e-04	430	55	5	35044719
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CCNT2 AHCYL1 PRRC2C PER1 AHCYL2	6.03e-04	432	55	5	23455922
Pubmed	A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development.	NRG2 PTCH1	6.08e-04	23	55	2	29532549
Pubmed	Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.	DDX20 PRPF8	6.08e-04	23	55	2	20696395
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	RBBP6 NCKIPSD NCKAP5	6.43e-04	106	55	3	18654987
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	KRT16 RBBP6 UBAP2L PRRC2C DDX20 PRPF8	6.91e-04	678	55	6	30209976
Pubmed	A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.	MTOR GOLGA3	7.20e-04	25	55	2	35211260
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	SETD1A PTCH1	7.79e-04	26	55	2	37228654
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	UBAP2L PRRC2C NAV1 DDX20 WNK1	8.15e-04	462	55	5	31138677
Pubmed	Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.	RBPJ MUC5AC	8.40e-04	27	55	2	21791528
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETD1A RBBP6 UBAP2L PRRC2C RBPJ	8.72e-04	469	55	5	27634302
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AHCYL1 NCKAP5 EXOC7 PRPF8 NR1D1 ARHGAP21 GOLGA3 BRWD1	8.84e-04	1285	55	8	35914814
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	USP31 AHCYL1 UBAP2L AGFG1 NAV1 ARHGAP21	9.37e-04	719	55	6	35337019
Pubmed	Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.	KRT16 PTCH1	9.70e-04	29	55	2	28049658
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	RBPJ MUC5AC	9.70e-04	29	55	2	21402740
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	UBAP2L PRRC2C PRPF8 ARHGAP21 GOLGA3	9.94e-04	483	55	5	36912080
Interaction	YWHAG interactions	MIIP DOCK4 USP31 FRMD4A HNF1A MTOR PRRC2C PAK5 NCKIPSD OSBPL7 AGFG1 NAV1 CGNL1 WNK1 ARHGAP21 CFAP97 TTLL7 ITPKB	2.55e-09	1248	55	18	int:YWHAG
Interaction	YWHAH interactions	MIIP DOCK4 USP31 FRMD4A MTOR PRRC2C PAK5 NCKIPSD AGFG1 NAV1 CGNL1 WNK1 ARHGAP21 CFAP97 TTLL7	1.60e-07	1102	55	15	int:YWHAH
Interaction	PLCD3 interactions	RANBP10 SETD1A AHCYL1 GPR156 DDX20 AHCYL2	9.43e-07	121	55	6	int:PLCD3
Interaction	BICD1 interactions	DOCK4 IFFO1 NCKIPSD NAV1 CGNL1 CFAP97 BRWD1	5.08e-06	250	55	7	int:BICD1
Interaction	YWHAZ interactions	MIIP USP31 HNF1A MTOR ASXL3 PAK5 NCKIPSD OSBPL7 NAV1 CGNL1 PRPF8 WNK1 ARHGAP21 GOLGA3	8.49e-06	1319	55	14	int:YWHAZ
Interaction	YWHAB interactions	MIIP DOCK4 USP31 HNF1A MTOR PAK5 NCKIPSD NAV1 CGNL1 WNK1 ARHGAP21 ITPKB	1.45e-05	1014	55	12	int:YWHAB
Interaction	SFN interactions	MIIP USP31 SETD1A MTOR PRRC2C NAV1 CGNL1 PRPF8 WNK1 ARHGAP21	1.54e-05	692	55	10	int:SFN
Interaction	YWHAE interactions	MIIP USP31 FRMD4A HNF1A MTOR PAK5 NCKIPSD NAV1 CGNL1 WNK1 ARHGAP21 GOLGA3 TTLL7	2.50e-05	1256	55	13	int:YWHAE
Interaction	FOXK2 interactions	AHCYL1 PRRC2C ASXL3 PER1 AHCYL2 EMSY	3.33e-05	225	55	6	int:FOXK2
Interaction	MAPRE3 interactions	DOCK4 NAV1 NCKAP5 DDX20 ARHGAP21 CFAP97	3.76e-05	230	55	6	int:MAPRE3
Interaction	SYT2 interactions	RANBP10 SETD1A AHCYL1 AHCYL2 WNK1	5.51e-05	150	55	5	int:SYT2
Interaction	CT45A5 interactions	RANBP10 SETD1A AHCYL1 AHCYL2	6.10e-05	78	55	4	int:CT45A5
Interaction	FBXO42 interactions	DOCK4 RBPJ AGFG1 NAV1 DDX20 WNK1	7.27e-05	259	55	6	int:FBXO42
Interaction	PTPN21 interactions	RANBP10 AHCYL1 PAK5 AHCYL2	1.21e-04	93	55	4	int:PTPN21
Interaction	NFKBIL1 interactions	SETD1A AHCYL1 GPR156 AHCYL2	1.21e-04	93	55	4	int:NFKBIL1
Interaction	PIP4K2B interactions	AHCYL1 AHCYL2 PTCH1 PRPF8	1.37e-04	96	55	4	int:PIP4K2B
Interaction	PRMT1 interactions	RANBP10 DSG1 UBAP2L PRRC2C ASXL3 VPS8 DDX20 PTCH1 PRPF8 GOLGA3	1.83e-04	929	55	10	int:PRMT1
Interaction	YWHAQ interactions	MIIP USP31 MTOR PAK5 NCKIPSD AGFG1 NAV1 CGNL1 PRPF8 WNK1 ARHGAP21	1.83e-04	1118	55	11	int:YWHAQ
Interaction	ARRB2 interactions	MIIP AHCYL1 PAK5 GPR156 AHCYL2 PTCH1 ARHGAP21	2.24e-04	454	55	7	int:ARRB2
Interaction	CLK4 interactions	AHCYL1 RBBP6 AHCYL2	2.35e-04	44	55	3	int:CLK4
Interaction	NAA40 interactions	DSG1 RBBP6 UBAP2L PRRC2C AGFG1 CGNL1 PRPF8 WNK1 ARHGAP21 EMSY	2.76e-04	978	55	10	int:NAA40
Cytoband	12p13.3	IFFO1 WNK1	6.00e-04	30	55	2	12p13.3
Cytoband	16p12.2	USP31 RBBP6	9.14e-04	37	55	2	16p12.2
Cytoband	1q42.13	PGBD5 ITPKB	1.60e-03	49	55	2	1q42.13
GeneFamily	CD molecules\|Mucins	MUC17 MUC3A MUC5AC	5.37e-06	21	30	3	648
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	CCNT2 IFFO1 OSBPL7 NAV1 WNK1	2.58e-05	166	55	5	M6826
Coexpression	GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN	DOCK4 DSG1 DEFB116 RBPJ AGFG1	5.99e-05	198	55	5	M9346
Coexpression	GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP	AHCYL1 CATSPER2 ASXL3 AHCYL2 WNK1	6.28e-05	200	55	5	M7776
Coexpression	GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP	CCNT2 HEG1 VPS8 OSBPL7 BRWD1	6.28e-05	200	55	5	M4884
Coexpression	GSE6875_WT_VS_FOXP3_KO_TREG_UP	FRMD4A VPS8 EMSY GOLGA3 BRWD1	6.28e-05	200	55	5	M6803
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML1	DOCK4 ASXL3 PAK5 PER1 NAV1 PLPPR3	6.35e-05	328	55	6	M39064
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 HEG1 PRRC2C CGNL1 ITPKB	3.37e-06	186	55	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 FRMD4A NAV1 NR1D1	4.67e-05	161	55	4	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 FRMD4A NAV1 NR1D1	4.67e-05	161	55	4	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 FRMD4A NAV1 NR1D1	4.67e-05	161	55	4	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 NCKAP5 CGNL1 NR1D1	6.04e-05	172	55	4	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 NCKAP5 CGNL1 NR1D1	6.04e-05	172	55	4	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1 BEGAIN	6.18e-05	173	55	4	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	DOCK4 NCKAP5 CGNL1 TTLL7	6.32e-05	174	55	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 PRRC2C ARHGAP21 GOLGA3	6.60e-05	176	55	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK4 USP31 FRMD4A ARHGAP21	6.75e-05	177	55	4	52c2ba74a8605260a2623e7d151286e504ac4d19
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HEG1 NCKAP5 CGNL1 TTLL7	7.68e-05	183	55	4	6821dca076318115d360ff426eb1218cfe104063
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCKAP5 CGNL1 PGBD5 TTLL7	8.35e-05	187	55	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRMD4A CGNL1 PTCH1 TTLL7	8.52e-05	188	55	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 HEG1 NCKAP5 TTLL7	8.88e-05	190	55	4	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 HEG1 NAV1 ITPKB	9.25e-05	192	55	4	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1 NRG2	9.25e-05	192	55	4	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	367C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRMD4A HEG1 NAV1 NCKAP5	9.43e-05	193	55	4	5c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell	367C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRMD4A HEG1 NAV1 NCKAP5	9.43e-05	193	55	4	d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 NAV1 NCKAP5 ITPKB	9.43e-05	193	55	4	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1 NRG2	9.43e-05	193	55	4	52e918884877b6659cdca0496390e440f73694a9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1 ITPKB	9.62e-05	194	55	4	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	DOCK4 FRMD4A RBPJ AGFG1	9.62e-05	194	55	4	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A AHCYL1 WNK1 ITPKB	9.82e-05	195	55	4	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1 ITPKB	1.00e-04	196	55	4	023312af38f816a44b407e0daa32590d953caf99
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	DOCK4 HEG1 NCKAP5 TTLL7	1.00e-04	196	55	4	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HEG1 NCKAP5 CGNL1 TTLL7	1.02e-04	197	55	4	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	ASK428-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DOCK4 HEG1 NCKAP5 TTLL7	1.04e-04	198	55	4	0047a9ef7684230ac5179efea94461480e90bdaf
ToppCell	Sigmoid-(1)_T_cell-(14)_Tcm\|Sigmoid / shred on region, Cell_type, and subtype	SETD1A HNF1A MTOR ITPKB	1.06e-04	199	55	4	ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCell	Sigmoid-T_cell-Tcm\|Sigmoid / Region, Cell class and subclass	SETD1A HNF1A MTOR ITPKB	1.06e-04	199	55	4	f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	KRT16 MUC17 NR1D1	1.33e-04	80	55	3	3413ac5e1c1e59eab6a83b889b870a8db4efccb9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	RBBP6 ASXL3 NCKAP5	6.18e-04	135	55	3	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	AT1-AT2_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	HEG1 NCKAP5 TTLL7	7.61e-04	145	55	3	cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	ASXL3 RBPJ PTCH1	8.23e-04	149	55	3	768877bade04ca0321593b8470b5011ad8270431
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP31 PAK5 NCKAP5	8.39e-04	150	55	3	aa11579a57d671a55e64183d35c1340fda6dec14
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RANBP10 HNF1A NR1D1	8.89e-04	153	55	3	ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RANBP10 HNF1A NR1D1	8.89e-04	153	55	3	90cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RANBP10 HNF1A NR1D1	8.89e-04	153	55	3	a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP31 GOLGA3 ITPKB	9.23e-04	155	55	3	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRG2 WNK1 ITPKB	9.75e-04	158	55	3	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	droplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASXL3 NRG2 PTCH1	1.01e-03	160	55	3	984990be02642a562f0c60ea99c01f005e7c02c2
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 NAV1 NR1D1	1.03e-03	161	55	3	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CATSPER2 NAV1 BEGAIN	1.05e-03	162	55	3	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 NCKAP5 CGNL1	1.10e-03	165	55	3	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 FRMD4A RBPJ	1.16e-03	168	55	3	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 FRMD4A RBPJ	1.16e-03	168	55	3	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 NCKAP5 CGNL1	1.16e-03	168	55	3	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IFFO1 ASXL3 ITPKB	1.18e-03	169	55	3	3f738fc56bbc70dc77c9ba41025631f8264cd2b3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1	1.18e-03	169	55	3	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT16 AHCYL2 MUC5AC	1.18e-03	169	55	3	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HEG1 CATSPER2 NCKAP5	1.18e-03	169	55	3	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HEG1 CATSPER2 NCKAP5	1.18e-03	169	55	3	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK4 FRMD4A PER1	1.18e-03	169	55	3	0867528101767fc65e93b3561480bf830c50368d
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 FRMD4A HEG1	1.20e-03	170	55	3	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DOCK4 HEG1 NCKAP5	1.20e-03	170	55	3	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 FRMD4A HEG1	1.20e-03	170	55	3	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	ILEUM-non-inflamed-(3)_mature_DC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NAV1 EFCAB3 ARHGAP21	1.20e-03	170	55	3	60151394460e6f27a42fab434e8b7b2adc78b128
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A NCKIPSD CGNL1	1.22e-03	171	55	3	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	PAK5 NRG2 GPR156	1.22e-03	171	55	3	cafcb7714110cb361808dbe4b9a4963bb71f5129
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRG2 WNK1 ITPKB	1.27e-03	173	55	3	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A AHCYL1 WNK1	1.27e-03	173	55	3	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A NCKAP5 AHCYL2	1.27e-03	173	55	3	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NRG2 EFCAB3 CGNL1	1.27e-03	173	55	3	ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	HEG1 NCKAP5 PGBD5	1.27e-03	173	55	3	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NRG2 EFCAB3 CGNL1	1.29e-03	174	55	3	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT16 NR1D1 MUC3A	1.29e-03	174	55	3	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue\|TCGA-Prostate / Sample_Type by Project: Shred V9	PAK5 NRG2 GPR156	1.29e-03	174	55	3	de6c1ebca36ec8060ddcafc270c45d6ab1caec2c
ToppCell	TCGA-Prostate-Solid_Tissue_Normal\|TCGA-Prostate / Sample_Type by Project: Shred V9	PAK5 NRG2 GPR156	1.29e-03	174	55	3	abdb5a89118b82bb64469fc41c163bd2b282b0c0
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue\|TCGA-Prostate / Sample_Type by Project: Shred V9	PAK5 NRG2 GPR156	1.29e-03	174	55	3	0dde0e9ef987c52cb29a238f15568a83424d02f6
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A PRRC2C WNK1	1.31e-03	175	55	3	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HEG1 NAV1	1.33e-03	176	55	3	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A AHCYL2 WNK1	1.33e-03	176	55	3	8e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK4 FRMD4A NR1D1	1.33e-03	176	55	3	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	NCKAP5 MUC3A TTLL7	1.33e-03	176	55	3	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	ICU-NoSEP-Myeloid-cDC1\|ICU-NoSEP / Disease, Lineage and Cell Type	FRMD4A NAV1 NCKAP5	1.35e-03	177	55	3	33cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP31 GOLGA3 ITPKB	1.37e-03	178	55	3	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C TTLL7 ITPKB	1.37e-03	178	55	3	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	facs-Marrow-KLS-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPJ NCKIPSD NAV1	1.37e-03	178	55	3	6bad4439a1692332f70135ff446a1048fa4c399d
ToppCell	facs-Marrow-KLS-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPJ NCKIPSD NAV1	1.37e-03	178	55	3	3f6feb4ed7779cf5684f52939350b41d7718c3c6
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 NAV1 TTLL7	1.40e-03	179	55	3	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKIPSD NRG2 GOLGA3	1.40e-03	179	55	3	6eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	SETD1A MTOR VPS8	1.40e-03	179	55	3	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKIPSD NRG2 GOLGA3	1.40e-03	179	55	3	2c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 MUC3A MUC5AC	1.40e-03	179	55	3	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCKAP5 CGNL1 TTLL7	1.40e-03	179	55	3	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 USP31 ITPKB	1.42e-03	180	55	3	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 MUC3A MUC5AC	1.42e-03	180	55	3	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 MUC3A MUC5AC	1.42e-03	180	55	3	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT16 NR1D1 EMSY	1.44e-03	181	55	3	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRG2 WNK1 ITPKB	1.44e-03	181	55	3	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT16 NR1D1 EMSY	1.44e-03	181	55	3	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	USP31 AHCYL1 ITPKB	1.44e-03	181	55	3	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	NCKAP5 CGNL1 TTLL7	1.49e-03	183	55	3	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 HEG1 NAV1	1.49e-03	183	55	3	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAV1 PTCH1 TTLL7	1.49e-03	183	55	3	6b5eef96b28911c752a8b6c0975918c4572cec38
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	MUC17 MUC3A MUC5AC	1.49e-03	183	55	3	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CATSPER2 VPS8 ARHGAP21	1.51e-03	184	55	3	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 USP31 NAV1	1.51e-03	184	55	3	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NCKAP5 CGNL1 TTLL7	1.51e-03	184	55	3	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NCKAP5 CGNL1 TTLL7	1.51e-03	184	55	3	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	MUC17 MUC3A MUC5AC	1.51e-03	184	55	3	d92a71441e4e19f8c301999d8186f8e48e3cd162
Drug	Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; HL60; HT_HG-U133A	VPS8 AHCYL2 EXOC7 NR1D1 WNK1 ITPKB	6.84e-06	192	55	6	2335_DN
Drug	Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	PER1 AHCYL2 NR1D1 EMSY ITPKB BRWD1	7.47e-06	195	55	6	6821_DN
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	FRMD4A HEG1 AHCYL2 NR1D1 WNK1 MUC5AC	7.69e-06	196	55	6	3256_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	CCNT2 SETD1A EXOC7 NR1D1 WNK1 ITPKB	7.92e-06	197	55	6	1640_DN
Drug	Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	DOCK4 CCNT2 SETD1A EXOC7 NR1D1 ITPKB	7.92e-06	197	55	6	5357_UP
Drug	Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	HNF1A DSG1 PER1 AGFG1 NR1D1 WNK1	8.15e-06	198	55	6	4343_UP
Drug	Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A	SETD1A HEG1 PER1 PTCH1 NR1D1 WNK1	8.39e-06	199	55	6	2257_DN
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	SETD1A PER1 PTCH1 NR1D1 WNK1 BRWD1	8.39e-06	199	55	6	3744_DN
Drug	Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SETD1A AHCYL2 EXOC7 NR1D1 WNK1 ITPKB	8.39e-06	199	55	6	5988_DN
Drug	N6-hydroxyadenosine	AHCYL1 AHCYL2	1.72e-05	3	55	2	CID000018881
Drug	RS)-AHPA	AHCYL1 AHCYL2	5.70e-05	5	55	2	CID000146832
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	PRRC2C AHCYL2 NR1D1 WNK1 BRWD1	9.06e-05	188	55	5	4845_DN
Drug	5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA	DOCK4 HEG1 PTCH1 EXOC7 NR1D1	9.52e-05	190	55	5	961_UP
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	EXOC7 EMSY TTLL7 ITPKB BRWD1	9.76e-05	191	55	5	1227_UP
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	CCNT2 RANBP10 AGFG1 EXOC7 ITPKB	9.76e-05	191	55	5	2055_DN
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	MIIP SETD1A HEG1 WNK1 EMSY	1.00e-04	192	55	5	2123_UP
Drug	Ricinine [524-40-3]; Down 200; 24.4uM; HL60; HT_HG-U133A	MIIP MTOR PER1 PLPPR3 AHCYL2	1.03e-04	193	55	5	2505_DN
Drug	Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A	MIIP HNF1A CATSPER2 IFFO1 EXOC7	1.03e-04	193	55	5	7229_UP
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	FRMD4A HNF1A PER1 EXOC7 BRWD1	1.03e-04	193	55	5	4670_UP
Drug	Kaempferol [520-18-3]; Down 200; 14uM; PC3; HT_HG-U133A	MIIP RANBP10 NRG2 PTCH1 NR1D1	1.03e-04	193	55	5	5839_DN
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A	MIIP MTOR PER1 EXOC7 NR1D1	1.03e-04	193	55	5	1664_DN
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A	HEG1 OSBPL7 NR1D1 TTLL7 BEGAIN	1.05e-04	194	55	5	2180_UP
Drug	H-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A	MTOR PER1 AGFG1 EXOC7 WNK1	1.05e-04	194	55	5	6921_UP
Drug	Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A	UBAP2L PER1 AHCYL2 PTCH1 ITPKB	1.05e-04	194	55	5	7354_DN
Drug	Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	MIIP CCNT2 HEG1 AGFG1 BRWD1	1.05e-04	194	55	5	4219_DN
Drug	Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MIIP SETD1A NR1D1 EMSY PGBD5	1.08e-04	195	55	5	5388_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	MIIP RANBP10 AHCYL2 EXOC7 EMSY	1.08e-04	195	55	5	2311_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	MIIP CCNT2 SETD1A HEG1 NRG2	1.08e-04	195	55	5	4326_DN
Drug	Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; MCF7; HT_HG-U133A	CCNT2 PER1 EXOC7 MUC5AC EMSY	1.10e-04	196	55	5	3333_DN
Drug	Cefadroxil [50370-12-2]; Up 200; 11uM; HL60; HT_HG-U133A	CATSPER2 PER1 PLPPR3 NR1D1 WNK1	1.10e-04	196	55	5	1323_UP
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	MIIP PER1 AHCYL2 NR1D1 BRWD1	1.10e-04	196	55	5	2687_DN
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; PC3; HT_HG-U133A	HEG1 MTOR NRG2 EXOC7 ITPKB	1.10e-04	196	55	5	5833_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HG-U133A	MIIP RANBP10 HNF1A AGFG1 WNK1	1.10e-04	196	55	5	203_DN
Drug	Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A	FRMD4A HEG1 PTCH1 MUC5AC BRWD1	1.10e-04	196	55	5	1708_UP
Drug	Riboflavine [83-88-5]; Down 200; 10.6uM; PC3; HT_HG-U133A	CCNT2 FRMD4A HEG1 NRG2 AHCYL2	1.13e-04	197	55	5	4485_DN
Drug	Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A	MIIP HNF1A HEG1 PER1 NR1D1	1.13e-04	197	55	5	1749_UP
Drug	Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	SETD1A HEG1 NRG2 PTCH1 BRWD1	1.13e-04	197	55	5	4620_UP
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	CCNT2 RANBP10 FRMD4A AHCYL2 EXOC7	1.13e-04	197	55	5	6984_DN
Drug	Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	CATSPER2 IFFO1 EXOC7 WNK1 BEGAIN	1.13e-04	197	55	5	5482_UP
Drug	Alcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A	CCNT2 UBAP2L PER1 NR1D1 ITPKB	1.13e-04	197	55	5	7345_DN
Drug	Nystatine [1400-61-9]; Down 200; 4.4uM; PC3; HT_HG-U133A	MIIP CCNT2 HEG1 PTCH1 BRWD1	1.13e-04	197	55	5	4223_DN
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; HL60; HT_HG-U133A	MIIP SETD1A NRG2 PTCH1 NR1D1	1.13e-04	197	55	5	1303_UP
Drug	Praziquantel [55268-74-1]; Down 200; 12.8uM; PC3; HT_HG-U133A	NRG2 PTCH1 WNK1 EMSY BRWD1	1.13e-04	197	55	5	5874_DN
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A	PTCH1 MUC5AC EMSY ITPKB BEGAIN	1.16e-04	198	55	5	6458_UP
Drug	Nomegestrol acetate [58652-20-3]; Up 200; 10.8uM; PC3; HT_HG-U133A	MIIP IFFO1 PER1 WNK1 BRWD1	1.16e-04	198	55	5	6362_UP
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A	MIIP HEG1 PER1 PTCH1 EXOC7	1.16e-04	198	55	5	3088_DN
Drug	Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A	MIIP PER1 WNK1 EMSY BRWD1	1.16e-04	198	55	5	7278_UP
Drug	Triamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A	MIIP HNF1A HEG1 IFFO1 TTLL7	1.16e-04	198	55	5	7307_UP
Drug	Ampyrone [83-07-8]; Up 200; 19.6uM; HL60; HG-U133A	MIIP HNF1A HEG1 CATSPER2 PLPPR3	1.16e-04	198	55	5	1402_UP
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA	RANBP10 UBAP2L RBPJ NCKIPSD AGFG1	1.16e-04	198	55	5	1070_DN
Drug	Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A	HEG1 AHCYL2 EXOC7 EMSY PGBD5	1.16e-04	198	55	5	5295_UP
Drug	Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; PC3; HT_HG-U133A	CCNT2 CATSPER2 EXOC7 NR1D1 EMSY	1.16e-04	198	55	5	5738_DN
Drug	Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; HL60; HG-U133A	MIIP CCNT2 RANBP10 AGFG1 NR1D1	1.18e-04	199	55	5	1442_DN
Drug	Leflunomide [75706-12-6]; Down 200; 14.8uM; HL60; HT_HG-U133A	MIIP EXOC7 NR1D1 EMSY BRWD1	1.18e-04	199	55	5	2539_DN
Drug	Iobenguane sulfate; Down 200; 10.8uM; MCF7; HT_HG-U133A	SETD1A MTOR AHCYL2 NR1D1 WNK1	1.18e-04	199	55	5	6002_DN
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A	CCNT2 CATSPER2 EXOC7 WNK1 BEGAIN	1.18e-04	199	55	5	4775_UP
Drug	losigamone	PER1 PTCH1	1.19e-04	7	55	2	CID000060572
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; PC3; HT_HG-U133A	HEG1 CATSPER2 IFFO1 WNK1 BEGAIN	1.21e-04	200	55	5	4006_UP
Drug	Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A	CCNT2 NCKIPSD AGFG1 PTCH1 EXOC7	1.21e-04	200	55	5	6789_DN
Drug	SCH 351591	PER1 NR1D1	1.59e-04	8	55	2	ctd:C459379
Drug	27764P	AHCYL1 AHCYL2	1.59e-04	8	55	2	CID005357051
Drug	3-deazaadenosylhomocysteine	AHCYL1 AHCYL2	2.04e-04	9	55	2	CID000124126
Drug	5'-noraristeromycin	AHCYL1 AHCYL2	2.55e-04	10	55	2	CID000126704
Drug	2-Amino-4-	AHCYL1 AHCYL2	3.11e-04	11	55	2	CID006326973
Drug	FPMPA	AHCYL1 AHCYL2	3.11e-04	11	55	2	CID000122652
Drug	niclosamide	DSG1 RBPJ	3.11e-04	11	55	2	CID000004477
Drug	5-Erfic	AHCYL1 AHCYL2	3.72e-04	12	55	2	CID000122653
Drug	MDL-28842	AHCYL1 AHCYL2	3.72e-04	12	55	2	CID006441200
Drug	2,6-diaminonebularine	AHCYL1 AHCYL2	4.39e-04	13	55	2	CID000072200
Drug	1H-1,2,4-triazole-3-carboxamide	AHCYL1 AHCYL2	4.39e-04	13	55	2	CID000065125
Drug	AC1L2Q2B	AHCYL1 AHCYL2	5.90e-04	15	55	2	CID000126283
Drug	CT 0	PER1 NR1D1	5.90e-04	15	55	2	CID002255489
Drug	anthocyanin	MTOR EMSY BRWD1	6.51e-04	70	55	3	CID000145857
Drug	Puromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A	HEG1 PER1 PTCH1 PGBD5	7.28e-04	168	55	4	5310_UP
Drug	AC1NRAL2	HEG1 KRT16 PRPF8	7.36e-04	73	55	3	CID005287959
Drug	S)-DHPA	AHCYL1 AHCYL2	7.61e-04	17	55	2	CID000073124
Drug	3-deazaaristeromycin	AHCYL1 AHCYL2	7.61e-04	17	55	2	CID000072501
Drug	fullerene C60	RANBP10 FRMD4A AHCYL1 IFFO1 PER1 NRG2 GPR156 NR1D1 GOLGA3 PGBD5 TTLL7	7.85e-04	1498	55	11	ctd:C069837
Drug	His-Ser	MTOR AGFG1	8.55e-04	18	55	2	CID000435727
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	RBBP6 PRRC2C AGFG1 WNK1	9.03e-04	178	55	4	3998_DN
Drug	cyclopentenyl cytosine	AHCYL1 AHCYL2	9.54e-04	19	55	2	CID000072828
Drug	8-azaadenosine	AHCYL1 AHCYL2	9.54e-04	19	55	2	CID000096410
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	FRMD4A UBAP2L NCKIPSD EMSY	9.80e-04	182	55	4	4376_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A	FRMD4A HEG1 RBBP6 UBAP2L	1.04e-03	185	55	4	5225_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	DOCK4 HEG1 PGBD5 TTLL7	1.08e-03	187	55	4	2474_UP
Drug	0297417-0002B [362658-29-5]; Up 200; 10uM; MCF7; HT_HG-U133A	PER1 EXOC7 MUC5AC BRWD1	1.08e-03	187	55	4	6902_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; HL60; HT_HG-U133A	RANBP10 PER1 EXOC7 EMSY	1.11e-03	188	55	4	1865_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	DOCK4 HEG1 PGBD5 TTLL7	1.13e-03	189	55	4	2904_UP
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	HEG1 PER1 EMSY PGBD5	1.13e-03	189	55	4	5208_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RBBP6 EMSY PGBD5 ITPKB	1.15e-03	190	55	4	5586_DN
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A	PRRC2C AGFG1 AHCYL2 WNK1	1.15e-03	190	55	4	4507_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	MIIP PER1 EXOC7 ITPKB	1.15e-03	190	55	4	1632_DN
Drug	Antimycin A [1397-94-0]; Down 200; 7.2uM; MCF7; HT_HG-U133A	DOCK4 SETD1A EXOC7 PGBD5	1.17e-03	191	55	4	2261_DN
Drug	lapatinib	MTOR NCKIPSD NRG2	1.18e-03	86	55	3	CID000208908
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	EXOC7 WNK1 MUC5AC BEGAIN	1.19e-03	192	55	4	6512_UP
Drug	Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A	MIIP FRMD4A PER1 WNK1	1.19e-03	192	55	4	2292_DN
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	CCNT2 HEG1 EMSY BRWD1	1.19e-03	192	55	4	1207_UP
Drug	GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A	HEG1 EXOC7 EMSY BRWD1	1.19e-03	192	55	4	7106_DN
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	UBAP2L EXOC7 NR1D1 EMSY	1.19e-03	192	55	4	2699_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	MIIP RANBP10 UBAP2L EXOC7	1.19e-03	192	55	4	1638_DN
Disease	respiratory system disease	OSBPL7 MUC5AC EMSY ITPKB	1.46e-04	145	54	4	EFO_0000684
Disease	cholangiocarcinoma (is_marker_for)	OSBPL7 MUC3A MUC5AC	2.23e-04	64	54	3	DOID:4947 (is_marker_for)
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	PTCH1 BRWD1	6.75e-04	21	54	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	NCKIPSD NAV1 PTCH1 TTLL7 BRWD1	8.00e-04	398	54	5	EFO_0003756, EFO_0003888, EFO_0004337
Disease	blood rubidium measurement	FRMD4A NCKAP5	1.04e-03	26	54	2	EFO_0021529
Disease	chronic obstructive pulmonary disease	RANBP10 SETD1A FRMD4A NAV1 PTCH1 EMSY	1.57e-03	688	54	6	EFO_0000341

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGSSSSSSSSVKQYI	CCNT2	641	O60583
YCKVSSSSSSSLSSS	CFAP97	166	Q9P2B7
QSSSCVSSTSSSYSS	CATSPER2	441	Q96P56
VSSTSSSYSSSSESR	CATSPER2	446	Q96P56
SSYSSSSESRFSESI	CATSPER2	451	Q96P56
TSSSYSSFSATSEEK	BEGAIN	296	Q9BUH8
DSESDSDSYSSRTSS	DDX20	651	Q9UHI6
SSSSASNLVSTQYTS	ASXL3	1326	Q9C0F0
SSSSSSSPSSVNYSE	RANBP10	416	Q6VN20
SSPSSVNYSESNSTD	RANBP10	421	Q6VN20
STASYLSSLSLSSST	PAK5	396	Q9P286
DESSSSSYASNSSSP	EZHIP	426	Q86X51
CASSSSYTTSSASDD	PER1	651	O15534
SFSSSTIYSTVSTST	MUC3A	401	Q02505
STTSFTSSTIYSTAS	MUC3A	1526	Q02505
SYSDSSSSSSERSSS	NRG2	21	O14511
QSYSSREVFTSSSSS	KRT16	436	P08779
SSSSLVLYQSSDSSN	HNF1A	591	P20823
ASSSVASSSVAYSTQ	MUC5AC	4766	P98088
SYSESSSTSSSESLN	HEG1	506	Q9ULI3
DSNSNLSVTNSSSYS	DEFB116	86	Q30KQ4
DGNDSDSSSYSSAST	GOLGA3	311	Q08378
SSTNYDTSTTSTDSS	DSG1	511	Q02413
DTSTTSTDSSQVYSS	DSG1	516	Q02413
SQETSSSATSYSSEF	EXOC7	526	Q9UPT5
SSSTLVDYTSTSSTG	RBBP6	1261	Q7Z6E9
AASLSSSSTSTSTTY	IFFO1	171	Q0D2I5
YSTSAASRSSSAASS	PGBD5	46	Q8N414
PSSSSSSSSSSSSFY	NR1D1	81	P20393
SHTSSTSSDSGSQYS	FRMD4A	946	Q9P2Q2
TSSDSGSQYSTSSQS	FRMD4A	951	Q9P2Q2
YSSSSLSSQASAEVS	DOCK4	1641	Q8N1I0
SSSSSTTPTSANSLY	CGNL1	296	Q0VF96
SESYSESSSDSSSRY	BRWD1	851	Q9NSI6
SLSSQHSYFDTESSS	GPR156	736	Q8NFN8
YTDSSSSSTESSQSS	EMSY	716	Q7Z589
SSSSSDTSECYTDSG	EFCAB3	411	Q8N7B9
STSSDTTADSFSSLN	OSBPL7	356	Q9BZF2
SLSESKSSQDSSDYS	MTOR	916	P42345
YSQASSSSTTADGTS	MUC17	1076	Q685J3
LSLASSASSTYSSAE	NAV1	1061	Q8NEY1
RSISQSSTDSYSSAA	AHCYL2	146	Q96HN2
SSTDSYSSAASYTDS	AHCYL2	151	Q96HN2
SYSSSSELSLSSTCS	NCKAP5	331	O14513
SISQSSTDSYSSAAS	AHCYL1	66	O43865
STDSYSSAASYTDSS	AHCYL1	71	O43865
SSASSTGFSSSYEDS	ITPKB	601	P27987
ASESSLESSSSYNSE	MIIP	36	Q5JXC2
YTTSSLSTKSTTTSD	PRRC2C	2321	Q9Y520
SGSDSSDSEYSSQTT	PTCH1	1216	Q13635
DSHSYDTSSVASSDS	VPS8	96	Q8N3P4
YSQDSAYSSSTTSTS	SETD1A	281	O15047
SSVSSTSLDTLYTSS	NCKIPSD	216	Q9NZQ3
SAATSSNAYTSTSNA	AGFG1	386	P52594
TSTTSNYETQTFSSK	PRPF8	2056	Q6P2Q9
PSSLYTSTASESSST	UBAP2L	546	Q14157
TASSSSASSDSSQYR	PLPPR3	556	Q6T4P5
NSEGSYTNASTNSTS	RBPJ	476	Q06330
YTNASTNSTSVTSST	RBPJ	481	Q06330
SLSDSYLDQTSSASS	TTC16	601	Q8NEE8
KSASALTYTASSTSA	USP31	1116	Q70CQ4
QYSLSQTSTSSEATT	WNK1	756	Q9H4A3
STITSDYSTTSSATY	ARHGAP21	1581	Q5T5U3
YCSSDSSYDSSSSSS	TTLL7	546	Q6ZT98
SSYDSSSSSSESDEN	TTLL7	551	Q6ZT98