Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

4.06e-104313911GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2T3 MC5R OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

6.81e-088843912GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2T3 MC5R OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 EGFR OR2T35 OR8B8 OR1L4

9.22e-0713533913GO:0004888
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

2.96e-104323911GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

6.45e-104653911GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

1.00e-094853911GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

2.26e-095243911GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

3.53e-095473911GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 PDE6C OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

5.07e-097223912GO:0051606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

6.72e-095823911GO:0050906
GeneOntologyBiologicalProcesssensory perception

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 PDE6C OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

3.87e-0710723912GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR2T3 MC5R OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

6.15e-0613953912GO:0007186
GeneOntologyBiologicalProcessGolgi to endosome transport

GBF1 DOP1A

5.23e-0418392GO:0006895
MousePhenoenlarged cecum

OR1E3 TMEM248 ICA1

3.90e-0547203MP:0009476
DomainOlfact_rcpt

OR2T3 OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

2.37e-093933610IPR000725
DomainGPCR_Rhodpsn_7TM

OR2T3 MC5R OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

3.09e-086703611IPR017452
Domain7tm_1

OR2T3 MC5R OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

3.44e-086773611PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2T3 MC5R OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

3.88e-086853611PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2T3 MC5R OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

4.24e-086913611PS50262
DomainGPCR_Rhodpsn

OR2T3 MC5R OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

4.30e-086923611IPR000276
Domain7TM_GPCR_Srsx

OR2T3 MC5R OR2T34

1.30e-03112363SM01381
Domainzf-C2H2_6

ZNF845 ZNF676 ZNF229 ZNF423

3.02e-03314364PF13912
DomainZINC_FINGER_C2H2_2

ZNF845 ZNF676 SUZ12 ZNF229 ZNF423

1.58e-02775365PS50157
DomainZINC_FINGER_C2H2_1

ZNF845 ZNF676 SUZ12 ZNF229 ZNF423

1.59e-02777365PS00028
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

2.85e-104172911M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR2T3 OR2T8 OR1E3 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

2.38e-086362911M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2T3 OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR2T33 OR8B8 OR1L4

5.20e-08389299M14091
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR2T8 OR2T1 OR1K1 OR2T2 OR2T34 OR8B8 OR1L4

4.62e-0921939712213199
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2T8 OR1E3 OR2T1 OR2T33 OR2T35 OR8B8 OR1L4

9.43e-0834039711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2T8 OR1E3 OR2T1 OR2T33 OR2T35 OR8B8 OR1L4

9.43e-0834039711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2T8 OR1E3 OR2T1 OR2T33 OR2T35 OR8B8 OR1L4

1.00e-0734339732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2T8 OR1E3 OR2T1 OR2T33 OR2T35 OR8B8 OR1L4

1.06e-0734639714611657
Pubmed

The human olfactory receptor gene family.

OR1E3 OR2T1 OR2T2 OR2T34 OR2T33 OR2T35 OR8B8 OR1L4

1.31e-0754139814983052
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR1E3 OR2T1 OR8B8

2.60e-06243939119360
Pubmed

The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.

EGFR UBR4

3.67e-06339230157281
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR2T8 OR2T2 OR2T35

1.91e-054639332126975
Pubmed

GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.

GBF1 EGFR

2.56e-05739218084281
Pubmed

A protein interaction landscape of breast cancer.

SUZ12 GBF1 FRMD6 EGFR UBR4

6.83e-0463439534591612
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

GBF1 EGFR TRAPPC12 ICA1 UBR4

9.92e-0468939536543142
Pubmed

Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos.

USP30 GBF1

1.03e-034239238529784
InteractionMUC4 interactions

FBXO22 SUZ12 EGFR

3.34e-079333int:MUC4
InteractionVOPP1 interactions

GBF1 EGFR TMEM259

1.13e-0613333int:VOPP1
Cytoband1q44

OR2T3 OR2T8 OR2T1 OR2T2 OR2T34 OR2T33 OR2T35

5.39e-121103971q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T3 OR2T8 OR2T1 OR2T2 OR2T34 OR2T33 OR2T35

1.58e-11128397chr1q44
Cytoband10q24

GBF1 PDE6C

4.11e-043539210q24
Cytoband9q33.2

OR1K1 OR1L4

5.11e-04393929q33.2
GeneFamilyOlfactory receptors, family 2

OR2T3 OR2T8 OR2T1 OR2T2 OR2T34 OR2T33 OR2T35

3.28e-10113287149
GeneFamilyOlfactory receptors, family 1

OR1E3 OR1K1 OR1L4

3.16e-0540283147
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF845 ZNF676 SUZ12 ZNF229 ZNF423

4.48e-0371828528
CoexpressionHALLMARK_PROTEIN_SECRETION

GBF1 EGFR ICA1 DOP1A

9.10e-0696364M5910
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-2|TCGA-Endometrium / Sample_Type by Project: Shred V9

OR2T3 OR2T2 OR2T34 OR2T35

1.94e-06105384744be8b4255bef3a973db7e4306e52387852e502
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RADIL ZNF676 FRMD6 ZNF423

1.51e-05176384b288116a4588a1f9db9d49af92cea118937c9201
DiseaseEndometrial Carcinoma

SUZ12 EGFR

2.78e-0372322C0476089
DiseaseAmphetamine Abuse

PDE6C ZNF423

3.01e-0375322C0236807
DiseaseAmphetamine Addiction

PDE6C ZNF423

3.01e-0375322C0236804
DiseaseAmphetamine-Related Disorders

PDE6C ZNF423

3.01e-0375322C0236733
Diseaseresponse to alcohol

OR2T8 EGFR

3.01e-0375322EFO_0005526
DiseaseGlioblastoma

SUZ12 EGFR

3.33e-0379322C0017636
DiseaseGiant Cell Glioblastoma

SUZ12 EGFR

3.76e-0384322C0334588
DiseaseGlioma

SUZ12 EGFR

4.02e-0387322C0017638
DiseaseAdenocarcinoma of large intestine

EGFR NRK

4.88e-0396322C1319315
DiseaseGlioblastoma Multiforme

SUZ12 EGFR

6.46e-03111322C1621958
DiseaseMalignant Neoplasms

SUZ12 EGFR

8.51e-03128322C0006826
DiseaseGlobal developmental delay

SUZ12 TRAPPC12

9.15e-03133322C0557874

Protein segments in the cluster

PeptideGeneStartEntry
LLNHMRLLHSLVTSA

UMODL1

191

Q5DID0
LRMISALTSHLQTLH

DOP1A

511

Q5JWR5
RLIRHLTITSEYQHM

ARMCX4

2146

Q5H9R4
ITLIRLNSHLHTPMY

OR8B8

46

Q15620
LHRLLTHYQLASAMG

RADIL

731

Q96JH8
LFHSYTTIMALIHLG

FBXO22

386

Q8NEZ5
TDLRLHTPMYFLLSH

OR2T1

101

O43869
SVSYTHILLTVHRMN

OR2T2

216

Q6IF00
IHSLYGHSMARTTNL

MGAM2

531

Q2M2H8
HRLHTPMYFLLSQLS

OR2T8

51

A6NH00
SIILRLHHTSYMYNI

PDE6C

221

P51160
HGLSSILQMLLSYHE

LANCL3

236

Q6ZV70
SLHNYIMTRILHSTG

TUBGCP5

896

Q96RT8
HPTHYSIRSTLRMEL

F8

2171

P00451
HRLHTPMYFLLSQLS

OR2T33

51

Q8NG76
SSYTLILHLIHRMNS

OR2T34

221

Q8NGX1
VSYTHILLTVHRMNS

OR2T35

216

Q8NGX2
SSYTLILHLIHRMNS

OR2T3

221

Q8NH03
LVSHVHSLLYILLMA

OR1K1

151

Q8NGR3
RHLLQLLSNSHRLYM

FRMD6

311

Q96NE9
MALESILHRIYTHQS

EGFR

881

P00533
VAIHSLAHMYTLSQL

KLHL11

206

Q9NVR0
LSVSMLLRYSHHQIF

TMEM259

316

Q4ZIN3
LVSLYIHMFLLARTH

MC5R

201

P33032
LMHTLHTRAASIYSS

GBF1

1501

Q92538
LTTAHATLHTLLMAR

OR1E3

151

Q8WZA6
LLSHMLATYQTTLLH

ICA1

226

Q05084
SISHLHSLFRVLLMS

OR1L4

151

Q8NGR5
STLRNHHSRVYFMTL

NRK

1556

Q7Z2Y5
DDRSLINLHLMHTSY

TMEM248

261

Q9NWD8
LTAINYLLSRHMAHK

RHEX

26

Q6ZWK4
SQMSSLVYHRRLHTG

ZNF845

421

Q96IR2
CMLSHLSQHERIYTR

ZNF676

151

Q8N7Q3
RHYLHESVLFNLTTM

TRAPPC12

686

Q8WVT3
IAPIFLHRTLTYMSH

SUZ12

106

Q15022
LHRTLTYMSHRNSRT

SUZ12

111

Q15022
FSYSSGLLMHQRLHT

ZNF229

526

Q9UJW7
SSTYLFRLMAVVVHH

USP30

431

Q70CQ3
SLLQHLTVHYMTTST

ZNF423

676

Q2M1K9
RNYLSVSLSEHHMAT

UBR4

671

Q5T4S7