Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionco-SMAD binding

USP9X USP9Y

4.48e-0512172GO:0070410
GeneOntologyMolecularFunctioncysteine-type peptidase activity

CTSD USP9X USP9Y

5.39e-04192173GO:0008234
GeneOntologyMolecularFunctionpeptidase activity

CTSD USP9X CD46 USP9Y

1.93e-03654174GO:0008233
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CTSD USP9X

2.39e-0386172GO:0004197
GeneOntologyMolecularFunctionSMAD binding

USP9X USP9Y

2.39e-0386172GO:0046332
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP9X USP9Y

4.15e-03114172GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP9X USP9Y

4.89e-03124172GO:0101005
GeneOntologyMolecularFunctionendopeptidase activity

CTSD USP9X CD46

5.39e-03430173GO:0004175
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP9X USP9Y

5.94e-03137172GO:0019783
GeneOntologyBiologicalProcesspositive regulation of programmed cell death

CTSD ITGA6 AIFM1 EMILIN1 SFPQ MARK4

1.83e-05739176GO:0043068
GeneOntologyBiologicalProcesscellular response to aldosterone

AIFM1 NR3C2

2.29e-059172GO:1904045
GeneOntologyBiologicalProcesscellular response to mineralocorticoid stimulus

AIFM1 NR3C2

5.78e-0514172GO:0071389
GeneOntologyBiologicalProcessresponse to aldosterone

AIFM1 NR3C2

1.20e-0420172GO:1904044
GeneOntologyBiologicalProcesscellular response to aldehyde

AIFM1 NR3C2

1.20e-0420172GO:0110096
GeneOntologyBiologicalProcesspositive regulation of apoptotic process

CTSD ITGA6 AIFM1 EMILIN1 SFPQ

2.20e-04718175GO:0043065
GeneOntologyCellularComponentintegrin complex

ITGA6 EMILIN1

3.04e-0432172GO:0008305
GeneOntologyCellularComponentacrosomal vesicle

SV2B FNDC3A CD46

5.79e-04206173GO:0001669
GeneOntologyCellularComponentsecretory granule

CTSD SV2B FNDC3A CD46 CHGB

1.01e-031014175GO:0030141
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA6 EMILIN1

1.04e-0359172GO:0098636
GeneOntologyCellularComponentsecretory vesicle

CTSD SV2B FNDC3A CD46 CHGB

2.53e-031246175GO:0099503
DomainUBA

SIK2 MARK4

7.21e-0444172IPR015940
DomainUBA

SIK2 MARK4

8.23e-0447172PS50030
DomainUSP_CS

USP9X USP9Y

1.62e-0366172IPR018200
DomainCa/CaM-dep_Ca-dep_prot_Kinase

SIK2 MARK4

1.76e-0369172IPR020636
DomainUSP_1

USP9X USP9Y

1.82e-0370172PS00972
DomainUCH

USP9X USP9Y

1.87e-0371172PF00443
DomainUSP_2

USP9X USP9Y

1.87e-0371172PS00973
DomainUSP_dom

USP9X USP9Y

1.92e-0372172IPR028889
DomainPeptidase_C19_UCH

USP9X USP9Y

1.92e-0372172IPR001394
DomainUSP_3

USP9X USP9Y

1.92e-0372172PS50235
DomainFN3

FNDC3A FLNC

1.20e-02185172SM00060
DomainFN3_dom

FNDC3A FLNC

1.52e-02209172IPR003961
DomainARM-like

USP9X USP9Y

2.45e-02270172IPR011989
PathwayPID_LKB1_PATHWAY

SIK2 CTSD MARK4

1.23e-0547143M87
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

2.25e-0721728922996
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

2.25e-07217212925892
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

2.25e-07217212895410
Pubmed

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

SIK2 USP9X MARK4

3.91e-073017316306228
Pubmed

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains.

USP9X MARK4

6.74e-07317218254724
Pubmed

Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

CTSD ITGA6 EMILIN1

8.10e-073817316263699
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

CTSD ITGA6 AIFM1 FLNC SFPQ

2.57e-0647717531300519
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

CTSD AIFM1 FLNC USP9X SFPQ

5.18e-0655117534728620
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

AIFM1 USP9X SFPQ USP9Y

7.36e-0626617419380743
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

AIFM1 USP9X SFPQ

1.00e-058717333711283
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

USP9X USP9Y

1.01e-05101729384609
Pubmed

Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease.

CTSD USP9X

1.23e-051117232140098
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

CTSD FNDC3A FLNC MARK4

1.25e-0530417432235678
Pubmed

Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.

USP9X USP9Y

1.48e-051217223861879
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

CTSD AIFM1 USP9X SFPQ

2.07e-0534617425324306
Pubmed

Deubiquitinating enzymes: a new class of biological regulators.

USP9X USP9Y

2.35e-05151729827704
Pubmed

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

SIK2 MARK4

2.35e-051517214976552
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

USP9X USP9Y

2.35e-051517214762062
Pubmed

A strategy for modulation of enzymes in the ubiquitin system.

USP9X USP9Y

3.05e-051717223287719
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

USP9X USP9Y

3.42e-051817212023983
Pubmed

OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways.

AIFM1 FLNC

3.83e-051917235941131
Pubmed

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.

CTSD AIFM1 FLNC

4.82e-0514717326465331
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

CTSD FLNC USP9X SFPQ

7.64e-0548417431995728
Pubmed

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.

ITGA6 KCNK1

7.84e-052717225758223
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

SIK2 MARK4

1.04e-043117231636950
Pubmed

Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.

CD46 SFPQ

1.11e-043217231815296
Pubmed

Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.

AIFM1 USP9X SFPQ

1.17e-0419817324337577
Pubmed

Profiling of Parkin-binding partners using tandem affinity purification.

AIFM1 SFPQ CHGB

1.25e-0420317324244333
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

AIFM1 FLNC USP9X

1.93e-0423517328378594
Pubmed

Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.

ITGA6 CD46

2.10e-044417230024968
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ITGA6 FNDC3A FLNC CD46 SFPQ

2.15e-04120317529180619
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

USP9X SFPQ USP9Y

2.16e-0424417329884807
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

ITGA6 EMILIN1

2.72e-045017223658023
Pubmed

Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

USP9X SFPQ

2.94e-045217224591637
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

AIFM1 USP9X SFPQ

2.97e-0427217325315684
Pubmed

The Effect of the NFκB-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.

FLNC USP9X

3.17e-045417235391932
Pubmed

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.

FLNC SFPQ

3.29e-045517233067418
Pubmed

Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.

ITGA6 CD46

3.29e-045517238945485
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

ITGA6 FLNC CD46

3.40e-0428517321423176
Pubmed

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.

USP9X SFPQ

3.53e-045717238223760
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

AIFM1 FLNC SFPQ USP9Y

3.59e-0472517427025967
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

CTSD EMILIN1 FNDC3A SFPQ

4.16e-0475417435906200
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

CTSD AIFM1 FLNC

4.43e-0431217337120454
InteractionNEAT1 interactions

CTSD USP9X SFPQ

9.98e-0724173int:NEAT1
InteractionCD151 interactions

ITGA6 FNDC3A CD46

1.57e-0559173int:CD151
InteractionCDC42 interactions

SIK2 ITGA6 AIFM1 FNDC3A FLNC USP9X MARK4

5.60e-051323177int:CDC42
GeneFamilyUbiquitin specific peptidases

USP9X USP9Y

6.10e-0456122366
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ITGA6 CD46

2.71e-02394122471
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

CTSD EMILIN1

7.47e-0520172MM17053
CoexpressionLAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX

SIK2 FNDC3A NR3C2

9.80e-05141173M39235
CoexpressionGSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP

ITGA6 SV2B CHGB

1.20e-04151173M421
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

ITGA6 FNDC3A NR3C2

1.22e-04152173M39239
CoexpressionGUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN

CTSD CD46

1.28e-0426172M1511
CoexpressionCUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE

ITGA6 AIFM1 FLNC

1.98e-04179173M39308
CoexpressionIL21_UP.V1_DN

ITGA6 CHGB USP9Y

2.22e-04186173M2824
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP

ITGA6 NR3C2 USP9Y

2.71e-04199173M4494
CoexpressionGSE22886_TCELL_VS_BCELL_NAIVE_UP

CTSD ITGA6 AIFM1

2.71e-04199173M4425
CoexpressionGSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_UP

CD46 CHGB USP9Y

2.71e-04199173M8223
CoexpressionGSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP

CTSD ITGA6 FLNC

2.75e-04200173M6988
CoexpressionTRAVAGLINI_LUNG_LYMPHATIC_CELL

CTSD EMILIN1 FLNC

3.13e-04209173M41670
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 FNDC3A NR3C2 KCNK1

7.32e-07192174f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

FNDC3A CD46 CHGB

1.74e-05135173ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

NR3C2 USP9Y KCNK1

3.00e-05162173b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD46 CHGB KCNK1

3.00e-05162173b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SV2B EMILIN1 FLNC

3.84e-051761735d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 NR3C2 SFPQ

3.97e-0517817301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NR3C2 CD46 KCNK1

4.53e-05186173acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 NR3C2 KCNK1

4.53e-05186173a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SV2B EMILIN1 FLNC

4.60e-0518717365d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SV2B EMILIN1 FLNC

4.60e-051871734c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SV2B EMILIN1 FLNC

4.60e-051871735274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 NR3C2 KCNK1

4.68e-05188173e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3A USP9X CHGB

4.90e-05191173fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3A USP9X CHGB

4.90e-05191173b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3A USP9X CHGB

4.90e-05191173657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SV2B EMILIN1 FLNC

4.98e-051921735f4f44f15d3a2846981e68296643a4634930a211
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SV2B EMILIN1 FLNC

4.98e-051921735e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CTSD SV2B EMILIN1

4.98e-05192173d43caf42ec744e895137f31ef65a990e250669d2
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN1 USP9X CHGB

5.06e-05193173fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

SV2B EMILIN1 FLNC

5.06e-0519317368eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN1 USP9X CHGB

5.06e-05193173471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SV2B EMILIN1 FLNC

5.13e-051941739441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SV2B EMILIN1 FLNC

5.21e-051951738e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCellCOVID-19_Severe-CD4+_T_activated|World / disease group, cell group and cell class

ITGA6 NR3C2 USP9Y

5.21e-0519517361d2d6c2d59799b3d877e622ccbcee9e84703a35
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SV2B EMILIN1 FLNC

5.21e-05195173f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 SFPQ KCNK1

5.45e-0519817377517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCellTCGA-Ovary-Primary_Tumor|TCGA-Ovary / Sample_Type by Project: Shred V9

EMILIN1 MARK4

7.31e-0410617214f548be39cec604fbdae0382cbf434fa4049840
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

EMILIN1 MARK4

7.31e-04106172939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

EMILIN1 MARK4

7.31e-04106172e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.16e-03134172b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCellTCGA-Bone_and_Soft_Tissue|World / Sample_Type by Project: Shred V9

EMILIN1 FLNC

1.16e-031341729940a710a5d6670244cce5e19f88b4195a59875b
ToppCellControl-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

FLNC CHGB

1.23e-03138172b7920c9a28d28220e7e4b30cd91ba13d0548eb76
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNC CHGB

1.30e-03142172191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FLNC CHGB

1.32e-03143172b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

EFCAB5 MARK4

1.43e-031491726e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 NR3C2

1.45e-0315017287968ce885a4959616f0321f58517fe8029ba1b1
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Thalamus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.51e-03153172e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.51e-03153172b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP|Thalamus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.51e-031531722513edfae62a44e51d3556675a096723194c966c
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Tfh|blood / Manually curated celltypes from each tissue

CHGB USP9Y

1.53e-031541725ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCellfacs-MAT-Fat-24m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGB KCNK1

1.57e-031561727433c6d4eb4d061844d8979c1e648d8ed56e1073
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

USP9Y KCNK1

1.59e-03157172542944030cd9b3f3559e64f9f6598694d74003c0
ToppCellPBMC-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

SV2B USP9Y

1.61e-031581725fefab4831687cd8dd45f5cc84f681398069c3be
ToppCell(03)_Secretory-(3)_72hpi|(03)_Secretory / shred by cell type and Timepoint

ITGA6 SFPQ

1.61e-0315817220563d03183b63aafc9c389f3f03781140702249
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SV2B CHGB

1.63e-031591727747cef94c55144fddcd024a7495318357f1351b
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.63e-0315917292049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SV2B KCNK1

1.65e-03160172b4844a8c7755a2b2868019791d8d224154973445
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SV2B KCNK1

1.65e-0316017201ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SV2B KCNK1

1.65e-031601726de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 CD46

1.69e-03162172c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SV2B FLNC

1.69e-031621722ac02523348660e514d464f8f2434ee0c312d784
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 CD46

1.69e-03162172f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 CD46

1.69e-031621725d902bb31e691aea9749617cc88303c2448f24b8
ToppCellP07-Endothelial-lymphatic_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSD NR3C2

1.71e-031631725cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCellP07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSD NR3C2

1.71e-03163172322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EFCAB5 CHGB

1.71e-03163172218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 MARK4

1.73e-031641725ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.75e-03165172570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

EMILIN1 FLNC

1.75e-031651722026a9a07f4d314cc05c167e491312b373468e46
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

SV2B FLNC

1.77e-031661726bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SV2B FLNC

1.77e-031661725ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SV2B FLNC

1.77e-03166172c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN1 CHGB

1.80e-03167172b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 NR3C2

1.80e-03167172edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellControl|World / group, cell type (main and fine annotations)

NR3C2 KCNK1

1.82e-03168172a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SV2B FLNC

1.82e-031681724977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SV2B CHGB

1.84e-031691728889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

ITGA6 KCNK1

1.88e-03171172adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

SV2B FLNC

1.88e-0317117207ff7059071da83da1d8f266a586573920d75b58
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 SV2B

1.88e-03171172121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SV2B CHGB

1.88e-03171172b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

EFCAB5 KCNK1

1.90e-03172172a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

EFCAB5 KCNK1

1.90e-0317217226006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

EMILIN1 FLNC

1.90e-03172172c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

ITGA6 SV2B

1.90e-03172172ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-031731723001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-03173172901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-03173172c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-03173172fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-03173172ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN1 FNDC3A

1.92e-0317317260e427f6c7d953cef5f692043670ff0b49cdce72
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.92e-03173172b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SV2B CHGB

1.95e-03174172ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SV2B CHGB

1.97e-031751729941c35601134d88d1b3249c81f8b43a8fc61610
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

SV2B CHGB

1.97e-031751724db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

ITGA6 FNDC3A

1.97e-03175172fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell343B-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SIK2 KCNK1

1.97e-03175172b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.97e-03175172c6c0196875f3b5293083cda6718300806a801941
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHGB KCNK1

1.97e-0317517219eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

SV2B CHGB

1.97e-031751728d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 FLNC

1.97e-0317517282c4d1edaa0d3b82d3ef4676d6f6516104a2656a
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGA6 KCNK1

1.99e-0317617245028197364c64e93e3ffe86aff773d47a477d49
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SV2B KCNK1

1.99e-03176172c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ITGA6 MARK4

1.99e-031761721e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SV2B FLNC

1.99e-03176172b288116a4588a1f9db9d49af92cea118937c9201
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SIK2 KCNK1

1.99e-031761721510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 KCNK1

1.99e-03176172cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCelldroplet-Kidney-nan-21m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 KCNK1

1.99e-031761720475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD46 KCNK1

1.99e-031761723bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EFCAB5 EMILIN1

2.01e-03177172c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
Drugcyanoketone

CTSD FNDC3A NR3C2

2.87e-0638173CID000020243
DrugFolic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A

SIK2 CD46 MARK4 KCNK1

1.14e-051951747201_UP
DrugHecogenin [467-55-0]; Up 200; 9.2uM; HL60; HT_HG-U133A

ITGA6 SV2B NR3C2 MARK4

1.21e-051981742716_UP
DrugDB07444

CTSD FNDC3A

3.45e-0512172CID006540255
Drug3',4'-dimethoxy-alpha-naphthoflavone

CTSD CD46

4.75e-0514172ctd:C557505
DrugIl 11

FNDC3A NR3C2

7.09e-0517172CID000146069
Drugthallium nitrate

CTSD AIFM1

7.09e-0517172ctd:C042172
Drugfluometuron

EMILIN1 NR3C2

7.09e-0517172CID000016562
DrugRU28318

AIFM1 NR3C2

8.91e-0519172CID003034004
DrugPVLA

ITGA6 FNDC3A

1.20e-0422172CID000126094
Drug1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one

CTSD ITGA6 SV2B FLNC

1.42e-04373174ctd:C540355
Drugbenzenesulfonyl

AIFM1 CD46

2.41e-0431172CID000012057
Drugphenformin

SIK2 MARK4

2.57e-0432172CID000008249
DrugBetamethasone-d5

ITGA6 AIFM1 FNDC3A NR3C2 CD46 CHGB

2.90e-041340176CID000003003
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

ITGA6 NR3C2 SFPQ

2.90e-041771734652_DN
DrugThioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; PC3; HG-U133A

SFPQ MARK4 KCNK1

3.15e-041821731905_UP
DrugKSCN

CTSD NR3C2

3.44e-0437172CID000516872
DrugCI-907

FNDC3A NR3C2

3.44e-0437172CID000005525
DrugNHE-1 inhibitor

AIFM1 NR3C2

3.44e-0437172CID011515636
DrugNSC311040

USP9X USP9Y

3.44e-0437172CID000329293
DrugAC1NDT8A

CTSD FNDC3A

3.44e-0437172CID004631218
Drug(+,-)-Synephrine [94-07-5]; Up 200; 24uM; HL60; HT_HG-U133A

SV2B EMILIN1 KCNK1

3.57e-041901736156_UP
DrugIkvav

ITGA6 FNDC3A

3.63e-0438172CID000131343
DrugAlbendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A

ITGA6 FNDC3A MARK4

3.68e-041921733164_DN
Drugprazosin hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA

SIK2 FNDC3A CD46

3.68e-04192173942_DN
DrugKainic Acid

AIFM1 SFPQ CHGB

3.79e-04194173ctd:D007608
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A

USP9X CD46 SFPQ

3.85e-04195173421_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A

CTSD NR3C2 MARK4

3.91e-041961732099_DN
DrugFipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SIK2 ITGA6 FNDC3A

3.97e-041971733176_DN
Drugrapamycin; Down 200; 0.1uM; MCF7; HG-U133A

ITGA6 FNDC3A CD46

3.97e-04197173326_DN
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

ITGA6 FNDC3A MARK4

3.97e-041971732306_DN
Drugcompound 21

NR3C2 CD46

4.03e-0440172CID005312128
Drugvirginiamycin complex

NR3C2 KCNK1

4.03e-0440172CID000005674
DrugAcetohexamide [968-81-0]; Down 200; 12.4uM; MCF7; HT_HG-U133A

SIK2 ITGA6 FNDC3A

4.03e-041981737482_DN
DrugMeptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

ITGA6 CD46 MARK4

4.09e-041991734774_UP
DrugTribenoside [10310-32-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

SIK2 ITGA6 MARK4

4.09e-041991733507_DN
DrugDibucaine [85-79-0]; Up 200; 11.6uM; PC3; HG-U133A

SIK2 CD46 MARK4

4.09e-041991731889_UP
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; HL60; HT_HG-U133A

NR3C2 CHGB MARK4

4.09e-041991733129_UP
DrugAlpha-D-Mannose

CTSD CD46

4.23e-0441172DB02944
Drugbenzamide

CTSD AIFM1

4.23e-0441172ctd:C037689
DrugBoc-D(OMe)-Fmk

CTSD AIFM1

5.56e-0447172CID009881695
Drugoxypertine

ITGA6 FNDC3A

6.04e-0449172CID000004640
Drugzotepine

CD46 CHGB

6.04e-0449172CID000005736
DrugNicotine

NR3C2 CD46 SFPQ CHGB KCNK1

6.43e-041000175ctd:D009538
DrugRgd Peptide

ITGA6 FNDC3A CD46

6.97e-04239173CID000104802
DrugAC1Q6RYL

CTSD CD46

7.07e-0453172CID000000606
DrugZfa-fmk

CTSD AIFM1

7.07e-0453172CID000122019
Diseaseresponse to trauma exposure

ITGA6 KCNK1

3.92e-0451172EFO_0008483
DiseaseKidney Diseases

CTSD SV2B

1.16e-0388172C0022658
DiseaseRheumatoid Arthritis

CTSD ITGA6

4.44e-03174172C0003873

Protein segments in the cluster

PeptideGeneStartEntry
PQAPVQGEDYGKGVI

AIFM1

551

O95831
PGQGVYYDFPRGVEK

C7orf31

221

Q8N865
VGIKQEPDDGSYYPE

NR3C2

491

P08235
SNYPGYPKPEEGILD

CD46

326

P15529
IGLGDYVPGEGYNQK

KCNK1

226

O00180
PEEGPYKVDITYDGH

FLNC

1031

Q14315
YPDIAVGAPYDDLGK

ITGA6

431

P23229
EPYQKSEQGPYGEII

EFCAB5

646

A4FU69
YVPPGYAPQVIEDNG

FNDC3A

76

Q9Y2H6
DAQYYGEIGIGTPPQ

CTSD

76

P07339
NIGYEGEELKPYTEP

MARK4

311

Q96L34
GGYEPEGLENKPVAE

EMILIN1

946

Q9Y6C2
EEEPEYGEEIKGYPG

CHGB

336

P05060
YGEEIKGYPGVQAPE

CHGB

341

P05060
DEGPGPPIKYQYAEL

USP9X

2211

Q93008
YEGEYQGIPHPDDVK

SV2B

46

Q7L1I2
PYAAPEVFEGQQYEG

SIK2

181

Q9H0K1
YGRGREEYEGPNKKP

SFPQ

691

P23246
LDEGPGPPIKYQYAE

USP9Y

2211

O00507