Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	embryonic skeletal system morphogenesis	HOXB4 HOXB6 HOXB7 HOXC4 SMAD2	3.08e-06	109	43	5	GO:0048704
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	BPTF HOXB4 HOXB6 HOXB7 HOXC4 SMAD2	1.17e-05	247	43	6	GO:0009952
GeneOntologyBiologicalProcess	embryonic skeletal system development	HOXB4 HOXB6 HOXB7 HOXC4 SMAD2	1.37e-05	148	43	5	GO:0048706
GeneOntologyBiologicalProcess	skeletal system morphogenesis	HOXB4 HOXB6 HOXB7 HOXC4 GLG1 SMAD2	2.23e-05	277	43	6	GO:0048705
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	BPTF HOXB4 HOXB6 HOXB7 HOXC4 ABL1 ACE TJP1 SMAD2	1.04e-04	929	43	9	GO:0009792
GeneOntologyBiologicalProcess	hematopoietic stem cell differentiation	HOXB4 ABL1 ACE	1.28e-04	47	43	3	GO:0060218
GeneOntologyBiologicalProcess	cell junction assembly	GJA4 CLSTN3 ABL1 ACE TJP1 ELFN1 SDK1	1.59e-04	569	43	7	GO:0034329
GeneOntologyBiologicalProcess	cholesterol catabolic process	SCARB1 SNX17	1.89e-04	10	43	2	GO:0006707
GeneOntologyBiologicalProcess	sterol catabolic process	SCARB1 SNX17	1.89e-04	10	43	2	GO:0016127
Domain	Homeobox_antennapedia	HOXB4 HOXB6 HOXB7 HOXC4	1.19e-08	12	43	4	IPR017995
Domain	Homeobox_Antennapedia_CS	HOXB4 HOXB6 HOXB7 HOXC4	1.42e-07	21	43	4	IPR001827
Domain	ANTENNAPEDIA	HOXB4 HOXB6 HOXB7 HOXC4	2.50e-07	24	43	4	PS00032
Domain	Homeobox_metazoa	HOXB4 HOXB6 HOXB7 HOXC4	5.39e-05	90	43	4	IPR020479
Domain	Integrin_alpha-2	ITGA10 ITGA2B	7.74e-04	18	43	2	IPR013649
Domain	Integrin_alpha2	ITGA10 ITGA2B	7.74e-04	18	43	2	PF08441
Domain	Integrin_alpha	ITGA10 ITGA2B	7.74e-04	18	43	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGA10 ITGA2B	7.74e-04	18	43	2	PS00242
Domain	Int_alpha_beta-p	ITGA10 ITGA2B	8.64e-04	19	43	2	IPR013519
Domain	Int_alpha	ITGA10 ITGA2B	8.64e-04	19	43	2	SM00191
Domain	Homeobox_CS	HOXB4 HOXB6 HOXB7 HOXC4	8.68e-04	186	43	4	IPR017970
Domain	FG_GAP	ITGA10 ITGA2B	1.16e-03	22	43	2	PS51470
Domain	FG-GAP	ITGA10 ITGA2B	1.38e-03	24	43	2	PF01839
Domain	FG-GAP	ITGA10 ITGA2B	1.38e-03	24	43	2	IPR013517
Domain	Integrin_dom	ITGA10 ITGA2B	1.50e-03	25	43	2	IPR032695
Domain	HECT	UBE3C NEDD4	1.75e-03	27	43	2	PF00632
Domain	HECTc	UBE3C NEDD4	1.75e-03	27	43	2	SM00119
Domain	HECT_dom	UBE3C NEDD4	1.75e-03	27	43	2	IPR000569
Domain	HECT	UBE3C NEDD4	1.75e-03	27	43	2	PS50237
Domain	Homeobox	HOXB4 HOXB6 HOXB7 HOXC4	2.02e-03	234	43	4	PF00046
Domain	HOMEOBOX_1	HOXB4 HOXB6 HOXB7 HOXC4	2.08e-03	236	43	4	PS00027
Domain	HOX	HOXB4 HOXB6 HOXB7 HOXC4	2.12e-03	237	43	4	SM00389
Domain	Homeobox_dom	HOXB4 HOXB6 HOXB7 HOXC4	2.18e-03	239	43	4	IPR001356
Domain	HOMEOBOX_2	HOXB4 HOXB6 HOXB7 HOXC4	2.18e-03	239	43	4	PS50071
Domain	-	HOXB4 HOXB6 HOXB7 HOXC4	4.00e-03	283	43	4	1.10.10.60
Domain	PX	SNX31 SNX17	4.61e-03	44	43	2	SM00312
Domain	PX	SNX31 SNX17	5.69e-03	49	43	2	PF00787
Domain	PX	SNX31 SNX17	5.91e-03	50	43	2	PS50195
Domain	-	SNX31 SNX17	6.15e-03	51	43	2	3.30.1520.10
Domain	Phox	SNX31 SNX17	6.38e-03	52	43	2	IPR001683
Domain	Homeodomain-like	HOXB4 HOXB6 HOXB7 HOXC4	7.01e-03	332	43	4	IPR009057
Pathway	WP_LDLRAD4_AND_WHAT_WE_KNOW_ABOUT_IT	SMAD2 NEDD4	9.10e-05	8	26	2	M39889
Pubmed	Expression of class I homeobox genes in fetal and adult murine skin.	HOXB4 HOXB6 HOXB7 HOXC4	1.20e-09	12	45	4	8105001
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ANKIB1 MAST1 BPTF PTPDC1 HOXB6 HOXC4 EOGT UBE3C PRKRIP1 MAN2B2 PLXDC2 SH3TC1 TJP1 SCARB1	3.14e-09	1489	45	14	28611215
Pubmed	Selectivity, sharing and competitive interactions in the regulation of Hoxb genes.	HOXB4 HOXB6 HOXB7	8.09e-09	4	45	3	9501100
Pubmed	The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.	HOXB4 HOXB6 HOXB7 HOXC4	1.17e-08	20	45	4	12370779
Pubmed	Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features.	HOXB4 HOXB6 HOXB7 HOXC4	1.44e-08	21	45	4	25381007
Pubmed	Organization of human class I homeobox genes.	HOXB4 HOXB6 HOXB7 HOXC4	1.76e-08	22	45	4	2576652
Pubmed	The human HOX gene family.	HOXB4 HOXB6 HOXB7 HOXC4	5.67e-08	29	45	4	2574852
Pubmed	Gene organization of murine homeobox-containing gene clusters.	HOXB4 HOXB6 HOXB7	7.06e-08	7	45	3	2906328
Pubmed	Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene.	HOXB4 HOXB6 HOXB7	7.06e-08	7	45	3	2463210
Pubmed	The murine and Drosophila homeobox gene complexes have common features of organization and expression.	HOXB4 HOXB6 HOXB7	7.06e-08	7	45	3	2566383
Pubmed	Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system.	HOXB4 HOXB6 HOXB7	1.13e-07	8	45	3	2570724
Pubmed	New murine homeoboxes: structure, chromosomal assignment, and differential expression in adult erythropoiesis.	HOXB4 HOXB6 HOXB7	1.13e-07	8	45	3	2890503
Pubmed	Expression of HOX homeogenes in human neuroblastoma cell culture lines.	HOXB4 HOXB6 HOXB7	1.13e-07	8	45	3	1981366
Pubmed	The murine Hox-2 genes display dynamic dorsoventral patterns of expression during central nervous system development.	HOXB4 HOXB6 HOXB7	1.69e-07	9	45	3	1685115
Pubmed	A yeast artificial chromosome containing the mouse homeobox cluster Hox-2.	HOXB4 HOXB6 HOXB7	1.69e-07	9	45	3	1972280
Pubmed	Region-specific gastrointestinal Hox code during murine embryonal gut development.	HOXB4 HOXB7 HOXC4	1.69e-07	9	45	3	11869294
Pubmed	Atlas of Hox gene expression in the developing kidney.	HOXB4 HOXB6 HOXB7 HOXC4	1.75e-07	38	45	4	15042701
Pubmed	Identification of 10 murine homeobox genes.	HOXB4 HOXB6 HOXB7 HOXC4	1.75e-07	38	45	4	1683707
Pubmed	Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.	HOXB4 HOXB6 HOXB7 HOXC4	1.95e-07	39	45	4	33257809
Pubmed	Quantification of Hox and surfactant protein-B transcription during murine lung development.	HOXB4 HOXB6 HOXB7 HOXC4	2.16e-07	40	45	4	19204410
Pubmed	Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.	HOXB4 HOXB6 HOXB7 HOXC4	2.39e-07	41	45	4	32479258
Pubmed	Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.	HOXB4 HOXB6 HOXB7	2.41e-07	10	45	3	2571936
Pubmed	Reduction of Hox gene expression by histone H1 depletion.	HOXB4 HOXB6 HOXB7 HOXC4	2.91e-07	43	45	4	22701719
Pubmed	Nomenclature for human homeobox genes.	HOXB4 HOXB6 HOXB7 HOXC4	3.20e-07	44	45	4	1973146
Pubmed	A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations.	HOXB4 HOXB6 HOXB7	3.32e-07	11	45	3	10885747
Pubmed	Vertebrate homeobox gene nomenclature.	HOXB4 HOXB6 HOXB7 HOXC4	4.19e-07	47	45	4	1358459
Pubmed	Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung.	HOXB4 HOXB6 HOXB7	4.42e-07	12	45	3	9415485
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	HOXB4 HOXB6 HOXB7 HOXC4 SCARB1	4.52e-07	118	45	5	16971476
Pubmed	New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.	HOXB4 HOXB6 HOXB7 HOXC4	5.39e-07	50	45	4	28188179
Pubmed	Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development.	HOXB4 HOXB6 HOXB7	5.74e-07	13	45	3	24525295
Pubmed	Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice.	HOXB4 HOXB6 HOXB7	7.29e-07	14	45	3	12753872
Pubmed	Hox genes and the evolution of vertebrate axial morphology.	HOXB4 HOXB7 HOXC4	1.12e-06	16	45	3	7768176
Pubmed	Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.	HOXB6 HOXB7 HOXC4	1.63e-06	18	45	3	23359544
Pubmed	Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice.	HOXB4 HOXB6 HOXC4	1.63e-06	18	45	3	9639506
Pubmed	The HOX homeodomain proteins block CBP histone acetyltransferase activity.	HOXB4 HOXB6 HOXB7	1.63e-06	18	45	3	11585930
Pubmed	Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments.	HOXB4 HOXB6	1.64e-06	2	45	2	8097432
Pubmed	HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4.	HOXB4 HOXC4	1.64e-06	2	45	2	22298821
Pubmed	Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.	HOXB4 HOXB6 HOXC4	2.65e-06	21	45	3	30254164
Pubmed	Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.	HOXB4 HOXB7 HOXC4	3.52e-06	23	45	3	28041967
Pubmed	Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.	HOXB4 HOXB6 HOXC4	4.02e-06	24	45	3	9367423
Pubmed	Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia.	HOXB4 HOXB6	4.91e-06	3	45	2	18553509
Pubmed	Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons.	HOXB6 HOXB7	4.91e-06	3	45	2	2891608
Pubmed	Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus.	HOXB6 HOXB7	4.91e-06	3	45	2	22603795
Pubmed	Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines.	HOXB6 HOXB7	4.91e-06	3	45	2	2573064
Pubmed	Fine mapping of human HOX gene clusters.	HOXB6 HOXB7 HOXC4	5.15e-06	26	45	3	8646877
Pubmed	Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.	HOXB4 HOXB6 HOXB7	7.22e-06	29	45	3	23843306
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	HOXB4 HOXB6 HOXC4	9.78e-06	32	45	3	37167859
Pubmed	Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus.	HOXB6 HOXB7	9.81e-06	4	45	2	3000607
Pubmed	Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.	HOXB6 HOXB7	9.81e-06	4	45	2	7729685
Pubmed	Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain.	HOXB4 HOXB6	9.81e-06	4	45	2	12514132
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	UBE3C NEDD4	1.63e-05	5	45	2	28425671
Pubmed	Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations.	HOXB6 HOXB7	1.63e-05	5	45	2	9108390
Pubmed	Complete mutation analysis panel of the 39 human HOX genes.	HOXB6 HOXB7 HOXC4	1.65e-05	38	45	3	11857506
Pubmed	Foxd1 is an upstream regulator of the renin-angiotensin system during metanephric kidney development.	HOXB7 ACE	2.45e-05	6	45	2	28665931
Pubmed	In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster.	HOXB6 HOXB7	2.45e-05	6	45	2	14623233
Pubmed	Prevalence of genetic risk factors for coronary artery disease in Corsica island (France).	ITGA2B ACE	2.45e-05	6	45	2	16248996
Pubmed	Sequence and embryonic expression of the murine Hox-3.5 gene.	HOXB4 HOXC4	3.42e-05	7	45	2	1363091
Pubmed	Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations.	HOXB4 HOXC4	3.42e-05	7	45	2	8660891
Pubmed	Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells.	ITGA2B ACE	4.56e-05	8	45	2	33480126
Pubmed	Hox genes regulate the onset of Tbx5 expression in the forelimb.	HOXB4 HOXC4	4.56e-05	8	45	2	22872086
Pubmed	LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage.	ITGA2B ACE	4.56e-05	8	45	2	27880904
Pubmed	Hox proteins drive cell segregation and non-autonomous apical remodelling during hindbrain segmentation.	HOXB4 TJP1	5.86e-05	9	45	2	24574009
Pubmed	Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes.	HOXB4 HOXB6	5.86e-05	9	45	2	21059868
Pubmed	Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code.	HOXB4 HOXC4	5.86e-05	9	45	2	10579975
Pubmed	A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins.	GJA4 NEDD4	5.86e-05	9	45	2	32272685
Pubmed	Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival.	ABL1 ITGA2B	5.86e-05	9	45	2	23840065
Pubmed	Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation.	HOXB6 HOXB7	5.86e-05	9	45	2	15087118
Pubmed	Genetic variants of connexin37 are associated with carotid intima-medial thickness and future onset of ischemic stroke.	GJA4 ACE	5.86e-05	9	45	2	21044781
Pubmed	NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.	SMAD2 NEDD4	5.86e-05	9	45	2	15496141
Pubmed	Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling.	TJP1 SMAD2	7.32e-05	10	45	2	19509472
Pubmed	Sex differences in environmental and genetic factors for hypertension.	GJA4 ACE	7.32e-05	10	45	2	18724972
Pubmed	Influence of polymorphisms in candidate genes on early vascular alterations in obese children.	GJA4 ACE	7.32e-05	10	45	2	20142115
Pubmed	Juxtaposed Polycomb complexes co-regulate vertebral identity.	HOXB4 HOXB6	7.32e-05	10	45	2	17107999
Pubmed	Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.	HOXB4 HOXB6	8.94e-05	11	45	2	12183370
Pubmed	Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.	HOXB4 HOXB6	8.94e-05	11	45	2	16024804
Pubmed	Nutrigenetics: links between genetic background and response to Mediterranean-type diets.	ACE SCARB1	8.94e-05	11	45	2	19689828
Pubmed	Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins.	GJA4 ITGA2B PLXDC2	9.99e-05	69	45	3	17192395
Pubmed	Integrins.	ITGA10 ITGA2B	1.07e-04	12	45	2	19693543
Pubmed	The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.	HOXB6 HOXC4	1.27e-04	13	45	2	8887324
Pubmed	A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.	HOXB4 HOXB6	1.27e-04	13	45	2	8625838
Pubmed	Organization and expression of mouse Hox3 cluster genes.	HOXB6 HOXC4	1.47e-04	14	45	2	8099712
Pubmed	Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity.	HOXB4 HOXB6	1.47e-04	14	45	2	19922872
Pubmed	A distinct Hox code for the branchial region of the vertebrate head.	HOXB4 HOXC4	1.70e-04	15	45	2	1682814
Pubmed	Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.	SNX31 SNX17	1.70e-04	15	45	2	28892079
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	TJP1 NEDD4	1.94e-04	16	45	2	21920314
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	BPTF EOGT UBE3C MAP7D3 TJP1 GLG1 SCARB1 SMAD2	2.31e-04	1297	45	8	33545068
Pubmed	Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.	HOXB4 TJP1	2.47e-04	18	45	2	12714971
Pubmed	E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.	GLG1 SMAD2	2.47e-04	18	45	2	20530870
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	ANKIB1 UBE3C NEDD4	2.58e-04	95	45	3	29643511
Pubmed	Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40.	GJA4 TJP1	2.76e-04	19	45	2	12435353
Pubmed	Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.	HOXB4 HOXB6	2.76e-04	19	45	2	15741318
Pubmed	FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.	HOXB7 TJP1	2.76e-04	19	45	2	23616926
Pubmed	Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.	TJP1 SMAD2	2.76e-04	19	45	2	22723298
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA10 ITGA2B	3.06e-04	20	45	2	22687584
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EFR3B MAST1 MAN2B2	3.18e-04	102	45	3	10231032
Pubmed	Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds.	EOGT NEDD4	3.38e-04	21	45	2	12124942
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	ABL1 UBE3C PLXDC2 SMAD2	3.42e-04	257	45	4	30945288
Pubmed	Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.	HOXB6 HOXB7	3.72e-04	22	45	2	26283362
Pubmed	Maternal immune activation leads to defective brain-blood vessels and intracerebral hemorrhages in male offspring.	TJP1 SMAD2	3.72e-04	22	45	2	36314682
Pubmed	Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.	ITGA2B ACE	3.72e-04	22	45	2	12871600
Cytoband	17q21.3	HOXB6 HOXB7	1.12e-04	16	45	2	17q21.3
Cytoband	17q21.32	HOXB4 ITGA2B	1.07e-03	49	45	2	17q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	HOXB4 HOXB6 HOXB7 ITGA2B	1.19e-03	473	45	4	chr17q21
Cytoband	4p16.1	MAN2B2 SH3TC1	2.76e-03	79	45	2	4p16.1
Cytoband	12q24.31	SCARB1 OGFOD2	2.83e-03	80	45	2	12q24.31
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	NSMCE3 TJP1	4.38e-03	100	45	2	chr15q13
GeneFamily	HOXL subclass homeoboxes	HOXB4 HOXB6 HOXB7 HOXC4	1.37e-06	52	29	4	518
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA10 ITGA2B	3.74e-04	18	29	2	1160
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX31 SNX17	9.82e-04	29	29	2	754
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	SPRED1 ITGA2B ELFN1	2.98e-03	181	29	3	694
Coexpression	GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP	GABRP MAP7D3 PLXDC2 ACE GLG1	1.52e-05	187	44	5	M7572
Coexpression	GSE12366_GC_BCELL_VS_PLASMA_CELL_DN	WSCD1 MAST1 HOXB4 HOXB7 ACE	1.81e-05	194	44	5	M3167
CoexpressionAtlas	gudmap_RNAseq_e15.5_Endothelial_2500_K0	HOXB4 HOXB6 HOXB7 SH3TC1 ACE	6.13e-06	126	44	5	gudmap_RNAseq_e15.5_Endothelial_2500_K0
CoexpressionAtlas	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K3	GJA4 HOXB4 HOXB6 HOXB7 EOGT	3.92e-05	185	44	5	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K3
CoexpressionAtlas	gudmap_RNAseq_p2_CD2APMEISWT_2500_K2	HOXB4 HOXB6 HOXB7 HOXC4	5.23e-05	99	44	4	gudmap_RNAseq_p2_CD2APMEISWT_2500_K2
CoexpressionAtlas	gudmap_RNAseq_e15.5_CollectIng Duct_2500_K4	WSCD1 SH3TC1 ACE	9.67e-05	43	44	3	gudmap_RNAseq_e15.5_CollectIng Duct_2500_K4
CoexpressionAtlas	kidney_P1_CapMes_Crym_top-relative-expression-ranked_200	HOXB4 HOXB6 HOXC4 PLXDC2	1.11e-04	120	44	4	gudmap_kidney_P1_CapMes_Crym_200
CoexpressionAtlas	kidney_P0_CapMes_Crym_top-relative-expression-ranked_200	HOXB4 HOXB6 HOXC4 PLXDC2	1.26e-04	124	44	4	gudmap_kidney_P0_CapMes_Crym_200
CoexpressionAtlas	DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#1_top-relative-expression-ranked_100	HOXB4 HOXB6	2.73e-04	12	44	2	gudmap_developingKidney_e12.5_renal vesicle_100_k1
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_200	WSCD1 HOXB4 HOXB6	3.02e-04	63	44	3	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k5
CoexpressionAtlas	Embryoid Body Cells-method_mRNA_vs_Embryoid Body Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	EFR3B MAST1 HOXB4 HOXB6 HOXC4	3.38e-04	293	44	5	PCBC_ratio_EB_from-mRNA_vs_EB_from-ESC_cfr-2X-p05
CoexpressionAtlas	Embryoid Body Cells-reprogram_OSKM-L_vs_Embryoid Body Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	EFR3B MAST1 HOXB4 HOXB6 HOXC4	3.38e-04	293	44	5	PCBC_ratio_EB_from-OSKM-L_vs_EB_from-ESC_cfr-2X-p05
CoexpressionAtlas	gudmap_RNAseq_e15.5_Mesangium_2500_K0	HOXB4 HOXB6 HOXB7	3.62e-04	67	44	3	gudmap_RNAseq_e15.5_Mesangium_2500_K0
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_200	HOXB4 HOXB6 HOXC4 PLXDC2	3.83e-04	166	44	4	gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_tips_2500_K2	HOXB4 HOXB6 HOXB7 HOXC4 SH3TC1	4.00e-04	304	44	5	gudmap_RNAseq_e11.5_Ureteric_tips_2500_K2
CoexpressionAtlas	DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_500	WSCD1 HOXB4 HOXB6	4.86e-04	74	44	3	gudmap_developingKidney_e15.5_S-shaped body_500_k5
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#1_top-relative-expression-ranked_200	HOXB4 HOXB6	4.94e-04	16	44	2	gudmap_kidney_e10.5_UretericTrunk_HoxB7_k1_200
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WSCD1 GJA4 SH3TC1 ACE LCMT2	1.26e-06	187	45	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WSCD1 GJA4 SH3TC1 ACE LCMT2	1.26e-06	187	45	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA10 ACE TJP1 SCARB1 NEDD4	1.58e-06	196	45	5	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	droplet-Heart-nan-18m-Endothelial-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFR3B HOXB7 CLSTN3 SH3TC1	7.99e-06	126	45	4	de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXB4 HOXB6 HOXB7 SH3TC1	2.78e-05	173	45	4	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell	normal_Lung-Endothelial_cells-EPCs\|normal_Lung / Location, Cell class and cell subclass	ITGA10 ACE TJP1 NEDD4	2.97e-05	176	45	4	71d1bd425772d89d8c550b909e0ec0e36ff22a7e
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXB4 HOXB6 HOXB7 SCARB1	2.97e-05	176	45	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 EOGT ACE TJP1	3.32e-05	181	45	4	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	GJA4 ACE TJP1 SCARB1	3.32e-05	181	45	4	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GJA4 SH3TC1 ACE TJP1	3.39e-05	182	45	4	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 EOGT ACE TJP1	3.46e-05	183	45	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	E12.5-Endothelial-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WSCD1 GJA4 EOGT SH3TC1	3.61e-05	185	45	4	e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	9aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCell	E12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WSCD1 GJA4 EOGT SH3TC1	3.61e-05	185	45	4	0bccc424d0466f7f82baa00127c733640a2d50fb
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	3beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	42939b294ea3e871274d8b73124c850dc1904fd2
ToppCell	Severe_COVID-19-Myeloid-transitional_Macro\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPRED1 PLXDC2 ACE SCARB1	3.61e-05	185	45	4	7a3612520ae4f0cd61480eadba31eecce001419d
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFR3B GJA4 SH3TC1 ACE	3.69e-05	186	45	4	e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 EOGT ACE	3.69e-05	186	45	4	b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 EOGT ACE	3.69e-05	186	45	4	8a8ed1502542d4895cba3fd5d534256206578716
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ACE TJP1 SCARB1	3.77e-05	187	45	4	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ACE TJP1 SCARB1	3.77e-05	187	45	4	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	E12.5-Endothelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WSCD1 GJA4 EOGT SH3TC1	3.77e-05	187	45	4	b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ACE TJP1 SCARB1	3.77e-05	187	45	4	81754e965848b718be20ee97ce072ce426938a69
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	3.77e-05	187	45	4	52ffd4be374e329ac8d321063f061b826d252956
ToppCell	facs-Lung\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE SCARB1	3.85e-05	188	45	4	f7292fc8e914f222828dcdb0a017d716207a97f6
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACE TJP1 SCARB1 NEDD4	3.85e-05	188	45	4	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	WSCD1 GJA4 SH3TC1 ACE	3.85e-05	188	45	4	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	facs-Lung\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE SCARB1	3.85e-05	188	45	4	e2b6e14579ec649a2bc106d9c99bb78ceb16ede3
ToppCell	droplet-Lung-LUNG-30m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	3.93e-05	189	45	4	25db316f66cee53774bb2b286cc457b37353356c
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 EOGT ACE TJP1	3.93e-05	189	45	4	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.01e-05	190	45	4	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	WSCD1 GJA4 SH3TC1 ACE	4.01e-05	190	45	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 EOGT ACE TJP1	4.09e-05	191	45	4	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE SCARB1	4.18e-05	192	45	4	6b69bb8fab9b470850eba1a070a500435ec233cd
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.18e-05	192	45	4	4fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WSCD1 ACE TJP1 SCARB1	4.18e-05	192	45	4	3c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.18e-05	192	45	4	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	droplet-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.18e-05	192	45	4	42e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	ff048e7fbab95d7914f3a636f6f014e7115d63d8
ToppCell	facs-MAT-Fat-3m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 TJP1 SCARB1	4.26e-05	193	45	4	e164f6403a8b541ced08a6feec915d2e855036ea
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	WSCD1 GJA4 SH3TC1 ACE	4.26e-05	193	45	4	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	droplet-Lung-nan-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	2f387fb763448b7c351da19a55765375e782c790
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.26e-05	193	45	4	097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell	droplet-Lung-nan-21m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	ae35c5757a88b02f8b9f94a0af4c3396ca828cc3
ToppCell	facs-MAT-Fat-3m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 TJP1 SCARB1	4.26e-05	193	45	4	b32533afeff1905e188becaa09079e9699722e4b
ToppCell	droplet-Lung-nan-21m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	4893b922e129711d5886bd4f3ee106e9e7065971
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	8748af38bfbbbb431ff9d9d5fa75934b5869293a
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.26e-05	193	45	4	ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCell	facs-MAT-Fat-3m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 TJP1 SCARB1	4.26e-05	193	45	4	2ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCell	droplet-Lung-21m-Endothelial-capillary_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	0d72cb6183062d48488c73320e48044d070fbcac
ToppCell	PND14-Endothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.35e-05	194	45	4	cee89d4340738f09d07a159cd6aeee4300776988
ToppCell	droplet-Lung-LUNG-1m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	68efc6df31479839a3bd5fe9fbc98ddceecc3b10
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFR3B GJA4 ACE SCARB1	4.35e-05	194	45	4	9d7cbbcf995274019ca10be0562f114513ec197a
ToppCell	droplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	e13923860a64ba9cf32df53c9f0cf4e7c321881d
ToppCell	droplet-Lung-nan-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	faaa7f18667e8943528fd0e92b7988e5b0607b54
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	WSCD1 GJA4 SH3TC1 ACE	4.35e-05	194	45	4	32ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCell	PND14-Endothelial-Endothelial_blood-vessel\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.35e-05	194	45	4	32962060d80f3edffbe9f0ecad3000c3a9817865
ToppCell	droplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	1a637809c0ec97374839c3476527e87eea75ed20
ToppCell	droplet-Lung-21m-Endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.35e-05	194	45	4	2c78e754cac848fd47172f94e392749eb0ab50d4
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 TJP1 NEDD4	4.35e-05	194	45	4	fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	f6c9cc362ccdbc7e790f7c8d1c56cab3557c5306
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.35e-05	194	45	4	c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	b49c19c33ad2e391d9367a4a2695b2fe87dd8a08
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ACE TJP1 SCARB1	4.35e-05	194	45	4	92a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	03985e4ab10f140f758e70dc7bfaa059b4e3bb18
ToppCell	droplet-Lung-1m-Endothelial-capillary_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	86508dd9b9d345b6624d185048cc92b81dd11c2a
ToppCell	droplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	1ac52b00ea0b0ddbd04f5d85fa8c086980a78926
ToppCell	droplet-Lung-1m-Endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	b1a25e3b36e7b7e558ef95ec22a3bdcbceae821f
ToppCell	droplet-Lung-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.35e-05	194	45	4	fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFR3B GJA4 ACE SCARB1	4.44e-05	195	45	4	2a6056172c41c46acfe0242be22269ef1d07921e
ToppCell	droplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 ACE TJP1	4.44e-05	195	45	4	27d1f228103ff5d8941aa8a8d15726cd09298a30
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.44e-05	195	45	4	e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCell	droplet-Bladder-Unstain-18m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFR3B GJA4 ACE SCARB1	4.44e-05	195	45	4	fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	WSCD1 GJA4 SH3TC1 ACE	4.44e-05	195	45	4	3826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.44e-05	195	45	4	5b84fd5be31386eb1d6048bbf28626032361842e
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.44e-05	195	45	4	52b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 TJP1 NEDD4	4.53e-05	196	45	4	9e737eaa98fd49972fce64d1d4a4d1f34b9bcb96
ToppCell	facs-Lung-ENDOMUCIN\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.53e-05	196	45	4	69f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCell	facs-Lung-ENDOMUCIN-18m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GJA4 ACE TJP1	4.53e-05	196	45	4	f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 TJP1 NEDD4	4.53e-05	196	45	4	99a7f2e57774884216525897dcd32a289107548b
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	ACE TJP1 SCARB1 NEDD4	4.53e-05	196	45	4	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	droplet-Lung-30m-Endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WSCD1 GJA4 TJP1 NEDD4	4.53e-05	196	45	4	58871891185aa7e1e4ab9b99cd25c1ca3c932cc8
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGA10 ACE SCARB1 NEDD4	4.80e-05	199	45	4	dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ACE TJP1 SCARB1 NEDD4	4.89e-05	200	45	4	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BPTF ACE TJP1 NEDD4	4.89e-05	200	45	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	BPTF GJA4 ACE TJP1	4.89e-05	200	45	4	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BPTF GJA4 ACE TJP1	4.89e-05	200	45	4	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ACE TJP1 SCARB1 NEDD4	4.89e-05	200	45	4	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACE TJP1 SCARB1 NEDD4	4.89e-05	200	45	4	105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCell	AT1_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	EFR3B WSCD1 PTPDC1	1.03e-04	90	45	3	6cbf30dd3992d8ccfaa74ad9781b9f8735f1ef69
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_mature\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MAN2B2 MAP7D3 PLXDC2	2.13e-04	115	45	3	c3f6efb90d5ee01af831f65e240505faa6a71dc0
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WSCD1 SNX31 ELFN1	2.48e-04	121	45	3	056d0f0f7a4d1b2d38b83647bbe4468b7c959ce6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WSCD1 SNX31 ELFN1	3.13e-04	131	45	3	3cb4b272e28ee9bad6d874f64a7aae18352a6cfb
Drug	C-cluster	GABRP HOXB6 MCAT HOXC4 GLG1	7.08e-06	139	44	5	CID000446537
Drug	perrhenate	MCAT ITGA2B GLG1	8.74e-06	21	44	3	CID000083718
Drug	Lucifer Yellow CH	MCAT SCARB1	1.09e-05	3	44	2	CID000093367
Drug	rosiglitazone maleate; Down 200; 10uM; PC3; HG-U133A	CNPPD1 WSCD1 CRYGD HOXB7 PRKRIP1	3.54e-05	194	44	5	430_DN
Drug	Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; PC3; HT_HG-U133A	EFR3B CRYGD HOXB7 ITGA2B SCARB1	3.71e-05	196	44	5	5800_UP
Drug	Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A	EFR3B ITGA10 GJA4 HOXC4 SH3TC1	3.81e-05	197	44	5	2809_UP
Drug	Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; HL60; HT_HG-U133A	EFR3B WSCD1 GJA4 TJP1 GLG1	3.90e-05	198	44	5	3140_UP
Drug	raloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A	CLSTN3 HOXC4 MAP7D3 SH3TC1 SCARB1	3.90e-05	198	44	5	202_DN
Drug	TAMA	MCAT TJP1	5.45e-05	6	44	2	CID000201762
Disease	leukemia (implicated_via_orthology)	HOXB4 HOXC4	3.49e-04	19	43	2	DOID:1240 (implicated_via_orthology)
Disease	Cerebral Hemorrhage	ITGA2B ACE	7.65e-04	28	43	2	C2937358
Disease	ureteral obstruction (biomarker_via_orthology)	GJA4 ABL1	1.97e-03	45	43	2	DOID:5199 (biomarker_via_orthology)
Disease	Male sterility	AURKC ACE	2.24e-03	48	43	2	C0917731
Disease	Male infertility	AURKC ACE	2.24e-03	48	43	2	C0021364
Disease	Kidney Failure, Chronic	ACE SCARB1	2.24e-03	48	43	2	C0022661
Disease	Subfertility, Male	AURKC ACE	2.24e-03	48	43	2	C0848676
Disease	cholestasis (biomarker_via_orthology)	ACE TJP1	2.34e-03	49	43	2	DOID:13580 (biomarker_via_orthology)
Disease	Acute Cerebrovascular Accidents	ITGA2B ACE	2.83e-03	54	43	2	C0751956

Protein segments in the cluster

Peptide	Gene	Start	Entry
ERCYLDLARLRGVHY	EOGT	451	Q5NDL2
HDARRVYLILEYAPR	AURKC	111	Q9UQB9
VYYCLRRRRRQEEKH	ELFN1	436	P0C7U0
YEEILRQARYRLRHG	CLSTN3	756	Q9BQT9
RQARYRLRHGAALYT	CLSTN3	761	Q9BQT9
AFVRRALHRRYGDRY	ACE	256	P12821
ALHRRYGDRYINLRG	ACE	261	P12821
EEYAEFQYRRRHRQR	ANKIB1	761	Q9P2G1
RRRYYRHSLLHLQGA	ADPRM	41	Q3LIE5
IRHEPIGYDRSRRKY	BPTF	456	Q12830
YHIQIRDLEDRLARY	CFAP157	41	Q5JU67
YGLHVRFRGEQQLRR	OGFOD2	26	Q6N063
DILGRTYYVNHESRR	NEDD4	621	P46934
ARELYYADLVRLARG	PERCC1	126	A0A1W2PR82
YLSERLIRDVGRHRY	EFR3B	56	Q9Y2G0
LIRDVGRHRYGYVCI	EFR3B	61	Q9Y2G0
YLIRQRHLLHGYEAR	PTPDC1	266	A2A3K4
GAVYLVRHRDTRQRF	MAST1	386	Q9Y2H9
VYRHLRRREYQRQDY	PRKRIP1	81	Q9H875
FHYNRYLTRRRRVEI	HOXB4	181	P17483
HYNRYLTRRRRIEIA	HOXB6	166	P17509
FHYNRYLTRRRRIEI	HOXB7	156	P09629
RVRELYAAARRVLGY	MCAT	86	Q8IVS2
LYRHAYRTEEQGRRL	GLG1	596	Q92896
VYIERLRHRNPDYLQ	CNPPD1	101	Q9BV87
GSHRIRLYEREDYRG	CRYGD	86	P07320
HYNRYLTRRRRIEIA	HOXC4	176	P09017
RSISLRYEGRVYHYR	ABL1	161	P00519
RRVLLRLYHLYEVGE	MAN2B2	911	Q9Y2E5
LYRTLERRRLADDYQ	MAP7D3	146	Q8IWC1
RVTRYGIAVLGHYLR	ITGA10	296	O75578
LRRYRQRYGVEALLH	KANSL2	261	Q9H9L4
VYLGHVIYLSRREER	GJA4	91	P35212
EHNGVLRGYILRYRL	SDK1	796	Q7Z5N4
GLEHLRLAQYTIERY	GABRP	201	O00591
VRRRTIYEYHRVELQ	PLXDC2	296	Q6UX71
VRERGPYVYREFRHK	SCARB1	86	Q8WTV0
YYRALRVARDLGQQR	SH3TC1	886	Q8TE82
LDSYYQRLHRLRGEQ	ITGA2B	301	P08514
ELAREVRHYGYLQLD	SNX31	261	Q8N9S9
RLAQTLRHYGYLRFD	SNX17	261	Q15036
EMTRRHIGRGVRLYY	SMAD2	326	Q15796
RDILIRRYADYRHPD	SPRED1	251	Q7Z699
DFVRQRYLEYRRIPH	NSMCE3	226	Q96MG7
SRNYEHRLRYEDRVP	TJP1	1071	Q07157
YGKRLLVVHYEELRR	WSCD1	481	Q658N2
ARRAPLIHRGYYVRA	LCMT2	46	O60294
RIAYIHLVADYRLNR	UBE3C	916	Q15386