Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone deacetylase binding

MTA2 MEF2B MEF2A MEF2C MEF2D

8.34e-06147385GO:0042826
GeneOntologyBiologicalProcesscardiac muscle hypertrophy

TOMM70 MEF2A MEF2C RYR2 CTDP1

5.26e-06142375GO:0003300
GeneOntologyBiologicalProcessstriated muscle hypertrophy

TOMM70 MEF2A MEF2C RYR2 CTDP1

6.03e-06146375GO:0014897
GeneOntologyBiologicalProcessmuscle hypertrophy

TOMM70 MEF2A MEF2C RYR2 CTDP1

6.44e-06148375GO:0014896
GeneOntologyBiologicalProcessregulation of cardiac muscle hypertrophy

TOMM70 MEF2A MEF2C CTDP1

2.69e-0597374GO:0010611
GeneOntologyBiologicalProcessregulation of muscle hypertrophy

TOMM70 MEF2A MEF2C CTDP1

3.04e-05100374GO:0014743
GeneOntologyBiologicalProcessmuscle tissue development

TOMM70 MEF2A MEF2C MEF2D TLL2 RYR2 CTDP1

5.19e-05558377GO:0060537
GeneOntologyBiologicalProcessregulation of muscle adaptation

TOMM70 MEF2A MEF2C CTDP1

9.25e-05133374GO:0043502
GeneOntologyBiologicalProcessregulation of developmental growth

TOMM70 MGLL SGPL1 MEF2C TLL2 CTDP1

9.49e-05421376GO:0048638
GeneOntologyBiologicalProcessmuscle structure development

TOMM70 MEF2B MEF2A MEF2C MEF2D TLL2 RYR2 CTDP1

1.14e-04858378GO:0061061
GeneOntologyBiologicalProcessmuscle organ development

MEF2B MEF2A MEF2C MEF2D TLL2 RYR2

1.15e-04436376GO:0007517
GeneOntologyBiologicalProcessmuscle adaptation

TOMM70 MEF2A MEF2C CTDP1

2.07e-04164374GO:0043500
GeneOntologyBiologicalProcessregulation of muscle system process

TOMM70 MEF2A MEF2C RYR2 CTDP1

2.42e-04317375GO:0090257
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

TOMM70 MEF2A MEF2C CTDP1

2.77e-04177374GO:0055007
GeneOntologyBiologicalProcesscardiac muscle tissue development

TOMM70 MEF2A MEF2C RYR2 CTDP1

2.79e-04327375GO:0048738
GeneOntologyBiologicalProcessheart development

TOMM70 MEF2B MEF2A MEF2C IFT172 RYR2 CTDP1

3.43e-04757377GO:0007507
GeneOntologyBiologicalProcessstriated muscle tissue development

TOMM70 MEF2A MEF2C RYR2 CTDP1

3.76e-04349375GO:0014706
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

MEF2C IFT172 RYR2

3.97e-0480373GO:0003143
GeneOntologyBiologicalProcessnegative regulation of cell growth involved in cardiac muscle cell development

TOMM70 CTDP1

4.19e-0417372GO:0061052
GeneOntologyBiologicalProcessventricular cardiac muscle cell differentiation

MEF2A MEF2C

5.25e-0419372GO:0055012
GeneOntologyBiologicalProcesscardiocyte differentiation

TOMM70 MEF2A MEF2C CTDP1

6.42e-04221374GO:0035051
GeneOntologyBiologicalProcessregulation of cardiac muscle tissue growth

TOMM70 MEF2C CTDP1

7.62e-04100373GO:0055021
GeneOntologyBiologicalProcesscirculatory system development

TSPAN12 TOMM70 MEF2B MEF2A SGPL1 MEF2C IFT172 RYR2 CTDP1

8.09e-041442379GO:0072359
GeneOntologyBiologicalProcessembryonic heart tube development

MEF2C IFT172 RYR2

8.31e-04103373GO:0035050
GeneOntologyBiologicalProcessroof of mouth development

SGPL1 MEF2C IFT172

8.54e-04104373GO:0060021
DomainMADS_MEF2-like

MEF2B MEF2A MEF2C MEF2D

1.30e-114374IPR033896
DomainMADS

MEF2B MEF2A MEF2C MEF2D

1.95e-106374SM00432
DomainMADS_BOX_1

MEF2B MEF2A MEF2C MEF2D

1.95e-106374PS00350
DomainSRF-TF

MEF2B MEF2A MEF2C MEF2D

1.95e-106374PF00319
DomainMADS_BOX_2

MEF2B MEF2A MEF2C MEF2D

1.95e-106374PS50066
DomainTF_MADSbox

MEF2B MEF2A MEF2C MEF2D

4.54e-107374IPR002100
DomainHJURP_C

MEF2A MEF2C MEF2D

2.86e-084373IPR022102
DomainHJURP_C

MEF2A MEF2C MEF2D

2.86e-084373PF12347
DomainLIPASE_SER

MGLL PGAP1

1.20e-0326372PS00120
DomainEF-hand_1

CLXN EFHD1 RYR2

3.35e-03152373PF00036
DomainEFh

CLXN EFHD1 RYR2

3.74e-03158373SM00054
DomainEF_HAND_2

CLXN EFHD1 RYR2

1.06e-02231373PS50222
DomainEF_hand_dom

CLXN EFHD1 RYR2

1.08e-02232373IPR002048
PathwayWP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION

MEF2B MEF2A MEF2C MEF2D

4.33e-0818294M39393
PathwayREACTOME_MYOGENESIS

MEF2B MEF2A MEF2C MEF2D

3.31e-0729294M853
PathwayWP_ENERGY_METABOLISM

MEF2B MEF2A MEF2C MEF2D

2.64e-0648294M39590
PathwayWP_CELL_DIFFERENTIATION_INDEX

MEF2B MEF2A MEF2C MEF2D

3.12e-0650294M39528
PathwayWP_CELL_DIFFERENTIATION_EXPANDED_INDEX

MEF2B MEF2A MEF2C MEF2D

6.08e-0659294M39723
PathwayREACTOME_MYOGENESIS

MEF2B MEF2C MEF2D

1.54e-0524293MM15174
PathwayWP_ADIPOGENESIS

MEF2B MEF2A MEF2C MEF2D

1.41e-04131294M39505
PathwayWP_ADIPOGENESIS_GENES

MEF2B MEF2A MEF2C MEF2D

1.68e-04137294MM15970
PathwayREACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION

MEF2A MEF2C MEF2D

2.60e-0461293M152
PathwayREACTOME_ERK_MAPK_TARGETS

MEF2A MEF2C

9.20e-0422292M13408
PathwayREACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT

POLR2A CTDP1

1.01e-0323292M3630
Pubmed

Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.

MEF2B MEF2A MEF2C MEF2D

1.35e-12439422764880
Pubmed

Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.

MEF2B MEF2A MEF2C MEF2D

1.35e-12439410207130
Pubmed

Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.

MEF2B MEF2A MEF2C MEF2D

1.35e-1243948575763
Pubmed

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.

MEF2B MEF2A MEF2C MEF2D

1.35e-12439421531906
Pubmed

Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.

MEF2B MEF2A MEF2C MEF2D

1.35e-1243947643214
Pubmed

MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.

MEF2B MEF2A MEF2C MEF2D

1.35e-12439425416778
Pubmed

Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.

MEF2B MEF2A MEF2C MEF2D

6.74e-12539419093215
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MEF2B MEF2A MEF2C MEF2D

6.74e-12539412694204
Pubmed

Expression of MEF2 genes during human cardiac development.

MEF2B MEF2A MEF2C MEF2D

6.74e-12539410458488
Pubmed

Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.

MEF2B MEF2A MEF2C MEF2D

6.74e-1253948993831
Pubmed

Regulatory role of MEF2D in serum induction of the c-jun promoter.

MEF2B MEF2A MEF2C MEF2D

6.74e-1253947760790
Pubmed

The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.

MEF2B MEF2A MEF2C MEF2D

6.74e-1253947646512
Pubmed

The expression of MEF2 genes is implicated in CNS neuronal differentiation.

MEF2B MEF2A MEF2C MEF2D

2.02e-1163949013788
Pubmed

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.

MEF2B MEF2A MEF2C MEF2D

9.42e-11839430205047
Pubmed

Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.

MEF2B MEF2A MEF2C MEF2D

2.82e-101039430276662
Pubmed

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

MEF2B MEF2A MEF2C MEF2D

4.43e-10113949162005
Pubmed

In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.

MEF2A MEF2C MEF2D

1.30e-09339322496871
Pubmed

Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.

MEF2A MEF2C MEF2D

1.30e-09339326286136
Pubmed

MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

MEF2A MEF2C MEF2D

1.30e-09339333315889
Pubmed

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

MEF2A MEF2C MEF2D

1.30e-09339327989458
Pubmed

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.

MEF2A MEF2C MEF2D

1.30e-09339318093911
Pubmed

Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

MEF2A MEF2C MEF2D

1.30e-09339315834131
Pubmed

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

MEF2B MEF2A MEF2C MEF2D

1.34e-091439412130539
Pubmed

MEF2C transcription factor controls chondrocyte hypertrophy and bone development.

MEF2B MEF2A MEF2C MEF2D

3.18e-091739417336904
Pubmed

Requirement of MEF2A, C, and D for skeletal muscle regeneration.

MEF2A MEF2C MEF2D

5.21e-09439324591619
Pubmed

Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice.

MEF2A MEF2C MEF2D

5.21e-09439331420455
Pubmed

Early expression of the different isoforms of the myocyte enhancer factor-2 (MEF2) protein in myogenic as well as non-myogenic cell lineages during mouse embryogenesis.

MEF2A MEF2C MEF2D

5.21e-0943938817457
Pubmed

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.

MEF2A MEF2C MEF2D

1.30e-08539320833138
Pubmed

Control of the SOST bone enhancer by PTH using MEF2 transcription factors.

MEF2A MEF2C MEF2D

1.30e-08539317696759
Pubmed

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

MEF2A MEF2C MEF2D

1.30e-08539323511190
Pubmed

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.

MEF2A MEF2C MEF2D

1.30e-0853938900141
Pubmed

Regulation of the MEF2 family of transcription factors by p38.

MEF2A MEF2C MEF2D

1.30e-0853939858528
Pubmed

Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.

MEF2B MEF2A MEF2C

1.30e-08539315084602
Pubmed

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.

MEF2A MEF2C MEF2D

1.30e-0853939753748
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2B MEF2A MEF2C

1.30e-08539316504037
Pubmed

MEF2 transcription factors are key regulators of sprouting angiogenesis.

MEF2A MEF2C MEF2D

1.30e-08539327898394
Pubmed

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.

MEF2A MEF2C MEF2D

2.60e-08639320399744
Pubmed

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases.

MEF2A MEF2C MEF2D

2.60e-08639310737771
Pubmed

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.

MEF2A MEF2C MEF2D

4.55e-0873938026334
Pubmed

Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

MEF2B MEF2A MEF2C

4.55e-08739312861002
Pubmed

RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.

MEF2B MEF2A MEF2C MEF2D

4.74e-083239420111592
Pubmed

Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development.

MEF2B MEF2A MEF2C MEF2D

4.74e-083239421768366
Pubmed

Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells.

MEF2B MEF2A MEF2C MEF2D

4.74e-083239425757744
Pubmed

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

MEF2A MEF2C MEF2D

7.27e-08839317786239
Pubmed

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.

MEF2A MEF2C MEF2D

7.27e-08839316043483
Pubmed

Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.

MEF2A MEF2C MEF2D

1.09e-0793939738004
Pubmed

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.

MEF2A MEF2C MEF2D

2.85e-071239328641113
Pubmed

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.

MEF2A MEF2C MEF2D

2.85e-071239316424906
Pubmed

Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.

MEF2A MEF2C MEF2D

3.70e-071339321447557
Pubmed

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.

MEF2A MEF2C MEF2D

4.70e-07143938114702
Pubmed

Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.

MEF2A MEF2C MEF2D

5.88e-071539319782130
Pubmed

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.

MEF2A MEF2C MEF2D

8.77e-071739327779093
Pubmed

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.

MEF2A MEF2C

1.23e-06239216469744
Pubmed

MEF2 negatively regulates learning-induced structural plasticity and memory formation.

MEF2A MEF2D

1.23e-06239222885849
Pubmed

Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

MEF2A MEF2C

1.23e-06239225336633
Pubmed

Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.

MEF2C MEF2D

1.23e-06239228738418
Pubmed

Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel.

MEF2A RYR2

1.23e-06239217431507
Pubmed

MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin heavy chain gene expression.

MEF2B MEF2A

1.23e-0623929430690
Pubmed

MEF2D and MEF2C pathways disruption in sporadic and familial ALS patients.

MEF2C MEF2D

1.23e-06239226921792
Pubmed

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.

MEF2A MEF2C

1.23e-06239217611778
Pubmed

Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors.

MEF2A MEF2D

1.23e-06239231722213
Pubmed

A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2.

MEF2A MEF2D

1.23e-06239230699340
Pubmed

MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells.

MEF2A MEF2D

1.23e-0623928798771
Pubmed

Loss of myocyte enhancer factor 2 expression in osteoclasts leads to opposing skeletal phenotypes.

MEF2A MEF2D

1.23e-06239232512162
Pubmed

Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.

MEF2A MEF2C

1.23e-06239221741404
Pubmed

Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c.

MEF2A MEF2C MEF2D

1.71e-062139317875930
Pubmed

Characterization of a cardiac-specific enhancer, which directs {alpha}-cardiac actin gene transcription in the mouse adult heart.

MEF2A MEF2D

3.67e-06339215491989
Pubmed

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

MEF2B MEF2A

3.67e-0633921516833
Pubmed

Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II.

POLR2A CTDP1

3.67e-06339218294453
Pubmed

Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.

MEF2B MEF2A

3.67e-06339215728583
Pubmed

Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D.

MEF2A MEF2D

3.67e-06339228901289
Pubmed

Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.

MEF2C MEF2D

3.67e-06339215743823
Pubmed

The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4.

MEF2A MEF2C

3.67e-06339211792813
Pubmed

Human SRF-related proteins: DNA-binding properties and potential regulatory targets.

MEF2B MEF2A

3.67e-0633921748287
Pubmed

MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.

MEF2A MEF2C

3.67e-06339224043307
Pubmed

Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation.

MEF2C MEF2D

3.67e-06339217101791
Pubmed

Essential control of early B-cell development by Mef2 transcription factors.

MEF2C MEF2D

3.67e-06339226660426
Pubmed

Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.

MEF2A MEF2C

7.34e-06439215140898
Pubmed

Regulation of cardiomyocyte Glut4 expression by ZAC1.

MEF2A MEF2D

7.34e-06439220363751
Pubmed

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.

MEF2A MEF2C

7.34e-0643928548800
Pubmed

MEF2 is restricted to the male gonad and regulates expression of the orphan nuclear receptor NR4A1.

MEF2A MEF2D

7.34e-06439224694307
Pubmed

HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.

MEF2C MEF2D

7.34e-06439210523670
Pubmed

Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7.

MEF2B MEF2A

7.34e-06439211585834
Pubmed

A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.

MEF2C MEF2D

7.34e-06439234290714
Pubmed

Big mitogen-activated kinase regulates multiple members of the MEF2 protein family.

MEF2A MEF2D

7.34e-06439210849446
Pubmed

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.

MEF2A MEF2C

7.34e-06439210330143
Pubmed

PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle.

MEF2C MEF2D

7.34e-06439236293168
Pubmed

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.

MEF2A MEF2C

7.34e-06439212061776
Pubmed

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.

MEF2A MEF2D

7.34e-06439211904443
Pubmed

Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation.

MEF2A MEF2C

7.34e-06439211809751
Pubmed

An HF-1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and established an anterior-posterior gradient of expression.

MEF2B MEF2A

7.34e-0643928674419
Pubmed

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2.

MEF2B MEF2D

7.34e-06439210531067
Pubmed

The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP.

POLR2A CTDP1

1.22e-05539212560496
Pubmed

Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer.

MEF2A MEF2D

1.22e-05539237772772
Pubmed

The control operated by the cell cycle machinery on MEF2 stability contributes to the downregulation of CDKN1A and entry into S phase.

MEF2C MEF2D

1.22e-05539225733682
Pubmed

HDAC4 integrates PTH and sympathetic signaling in osteoblasts.

MEF2A MEF2C

1.22e-05539224934156
Pubmed

Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.

MEF2A MEF2D

1.83e-05639210825153
Pubmed

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

MEF2A MEF2C

1.83e-05639222135324
Pubmed

The BRCT domain is a phospho-protein binding domain.

POLR2A CTDP1

1.83e-05639214576433
Pubmed

Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression.

MEF2A MEF2D

1.83e-05639220590529
InteractionMEF2B interactions

MEF2B MEF2A MEF2C MEF2D

3.91e-0911394int:MEF2B
InteractionBORCS8-MEF2B interactions

MEF2B MEF2A MEF2C MEF2D

1.61e-0815394int:BORCS8-MEF2B
InteractionMEF2C interactions

MEF2B MEF2A MEF2C MEF2D

3.53e-0654394int:MEF2C
InteractionMEF2A interactions

MEF2B MEF2A MEF2C MEF2D

1.39e-0576394int:MEF2A
InteractionCABIN1 interactions

MEF2B MEF2A MEF2D POLR2A

1.97e-0583394int:CABIN1
InteractionMEF2D interactions

MEF2B MEF2A MEF2C MEF2D

2.37e-0587394int:MEF2D
InteractionASCL1 interactions

MEF2A MEF2C MEF2D

8.99e-0545393int:ASCL1
Cytoband11q22.3

CWF19L2 RAB39A

6.50e-044439211q22.3
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B MEF2A MEF2C MEF2D

3.36e-124264649
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B MEF2A MEF2C MEF2D

1.68e-1152641086
GeneFamilyEF-hand domain containing

CLXN EFHD1 RYR2

3.71e-03219263863
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP

TXNDC16 RAB39A GLOD4 PELO CTDP1

1.15e-05200395M7148
CoexpressionTURJANSKI_MAPK11_TARGETS

MEF2A MEF2C

2.15e-055392M2492
CoexpressionTURJANSKI_MAPK7_TARGETS

MEF2A MEF2C

4.51e-057392M11218
CoexpressionTURJANSKI_MAPK14_TARGETS

MEF2A MEF2C

9.63e-0510392M14718
CoexpressionGSE3982_DC_VS_NKCELL_DN

GLOD4 MEF2C RYR2 PICK1

2.07e-04197394M5480
CoexpressionGSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN

RAB39A FAM3B IFT172 MEF2D

2.15e-04199394M9332
CoexpressionGSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP

AARS1 EFHD1 MEF2D POLR2A

2.15e-04199394M7650
CoexpressionGSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN

PTPN9 MEF2A MEF2D TLL2

2.15e-04199394M4049
CoexpressionGSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_UP

TSPAN12 UGGT2 HAGH RYR2

2.20e-04200394M8117
CoexpressionGSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN

TOMM70 SPAG7 GLOD4 MEF2C

2.20e-04200394M7744
CoexpressionGSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN

TXNDC16 PDE7A MEF2C MEF2D

2.20e-04200394M5966
CoexpressionHALLMARK_MYOGENESIS

MEF2A MEF2C MEF2D PICK1

2.20e-04200394M5909
CoexpressionGSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP

MGLL FAM3B MEF2A MEF2C

2.20e-04200394M7294
CoexpressionGSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP

TXNDC16 LIMD1 MEF2C POLR2A

2.20e-04200394M8550
CoexpressionGSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN

TXNDC16 GLOD4 MEF2C PGAP1

2.20e-04200394M9791
CoexpressionGSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP

TXNDC16 TOMM70 LIMD1 MEF2C

2.20e-04200394M8532
CoexpressionGSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN

TSPAN12 HAGH LIMD1 MEF2A

2.20e-04200394M3929
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B PELO MEF2C RYR2

1.75e-05178394e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCelldroplet-Fat-Scat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL PELO RYR2

1.91e-05182394fea094fe0e7796c084e60b5310c1559658633f7a
ToppCell11.5-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

MGLL KCNA4 PELO MEF2C

2.17e-05188394916971d8660fd20f616346953874e89d2cd13e88
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MGLL KCNA4 MEF2C RYR2

2.35e-051923945000440dc1ed17e7474d340921bdff945646f27e
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B PELO EFHD1 MEF2C

2.60e-051973941c91e3afcc5be195b827a1dff83aff5cc2492456
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B MAOA IFT172 PGAP1

2.60e-05197394c0250509836f1be04f5e54386191d7bb1e1da652
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B PELO EFHD1 MEF2C

2.71e-05199394f1723cfd6fbb8c8903a3b167872ec8523e3be250
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TSPAN12 MGLL MEF2A MEF2C

2.76e-0520039458a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

MEF2B PELO MEF2C RYR2

2.76e-05200394b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / Treatment groups by lineage, cell group, cell type

TSPAN12 MGLL MEF2A MEF2C

2.76e-05200394b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLOD4 EFHD1 TLL2

2.09e-04132393dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLOD4 EFHD1 TLL2

2.09e-0413239360ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLOD4 EFHD1 TLL2

2.33e-041373935e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B PDE7A MEF2C

3.60e-0415939374655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

UGGT2 PDE7A MEF2C

3.81e-0416239391ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL HAGH HECTD4

3.95e-0416439318eeda51e69722992c3a7f699be293535a90868b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B PDE7A MEF2C

4.02e-0416539322293c6b55f44636440cd737efb786ff5de3373d
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL FAM3B MAOA

4.02e-04165393ce79d217df88035457cd58f679e72dd98722ae22
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL FAM3B MAOA

4.09e-0416639322b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL HAGH HECTD4

4.23e-04168393d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE7A MEF2C PGAP1

4.23e-04168393784ce773521e5d74570f45120e56d112bc76ff49
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL HAGH HECTD4

4.23e-0416839308fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEF2C RYR2 HECTD4

4.38e-041703935570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL FAM3B MAOA

4.38e-0417039375b0486620cab838d3feb1c3aa965b487a906618
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE7A MEF2C PGAP1

4.38e-041703937a4ed69c807c3761210776e8fe6680d1bd892e82
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

KCNA4 EFHD1 RYR2

4.46e-04171393bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B TLL2 PGAP1

4.61e-0417339323e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B IFT172 PGAP1

4.77e-041753930431897d7fcc9cefb516cd36987cf18b7f19a26a
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL FAM3B MAOA

4.85e-041763937622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

RYR2 PGAP1 HERC5

4.93e-04177393a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

RYR2 PGAP1 HERC5

5.01e-04178393ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL HAGH HECTD4

5.09e-041793937e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAM3B MEF2A MEF2C

5.18e-0418039352e76709fa95a884ac5d910b83bd173616dac340
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE7A MEF2A MEF2C

5.18e-04180393eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B MEF2C PGAP1

5.18e-04180393b51b10781082bc0305ba6a81e978729b329f7771
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NBPF3 AARS1 RYR2

5.18e-041803938e96f8646c002768b272359af485dc0ab57e0ccd
ToppCelldroplet-Marrow-BM|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 MGLL LIMD1

5.26e-041813934169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP2R5B MEF2A MEF2C

5.26e-041813930bc58c8942491e7ee5b858c5742770df7677532f
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

MGLL MAOA RYR2

5.35e-041823937af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

MGLL MAOA RYR2

5.35e-04182393e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC16 MEF2C PGAP1

5.43e-0418339320f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 MEF2C HERC5

5.43e-04183393e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MGLL PTPN9 MEF2A

5.52e-041843932c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 SGPL1 PGAP1

5.52e-04184393382b1e90b3f437af596750669c0465a169d97095
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TSPAN12 MAOA EFHD1

5.61e-04185393c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MGLL MAOA PGAP1

5.69e-0418639392092f11ecce22c14f244e42c499af0822977e6f
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LIMD1 IFT172 HECTD4

5.69e-04186393bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFHD1 MEF2C RYR2

5.69e-041863934780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE7A MEF2C PGAP1

5.69e-04186393d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHD1 RYR2 PGAP1

5.69e-041863938eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSPAN12 MGLL TLL2

5.69e-04186393cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFHD1 MEF2C RYR2

5.69e-04186393a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC16 MEF2C PGAP1

5.78e-04187393b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC16 MEF2C PGAP1

5.78e-041873933ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LIMD1 RYR2

5.87e-041883936468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LIMD1 RYR2

5.87e-041883937a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LIMD1 RYR2

5.87e-041883939cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B EFHD1 MEF2C

5.87e-04188393c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC16 MEF2C PGAP1

5.87e-041883931f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC16 MEF2C PGAP1

5.87e-0418839385746f95319e494efdc1bbc24331698688d3a900
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 MGLL MEF2C

5.97e-04189393e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFHD1 MEF2C RYR2

5.97e-04189393975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

TSPAN12 EFHD1 MEF2C

5.97e-041893939c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TXNDC16 MEF2C RYR2

6.06e-041903936e92c78799f34b31d098854503c796edb0dc7f80
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B EFHD1 MEF2C

6.06e-04190393a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 MGLL MEF2A

6.15e-04191393718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 MGLL MEF2A

6.15e-04191393454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MGLL MAOA EFHD1

6.24e-04192393fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MGLL KCNA4 MEF2C

6.24e-0419239355f95454399fd533df75db06584eaa48d6ee3830
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 MGLL MEF2C

6.24e-041923935012cc3ec0766f06af447463413422b484446c43
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL EFHD1 PGAP1

6.24e-041923936fb56d062c35617b18b927704bf5fba894faed81
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HAGH MAOA EFHD1

6.24e-04192393e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 MEF2A MEF2C

6.24e-0419239369758a256386a6ed3a6e2c94c55d59baa34892d7
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL RYR2

6.34e-0419339354024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL RYR2

6.34e-0419339381d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 MEF2A MEF2C

6.34e-04193393b52d5661edff83ac4c5fe2bf89d6672016bb827b
ToppCell18-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

MGLL EFHD1 MEF2C

6.34e-041933939f4ba9c29ab8071d57e4187085ec3a47ab61e968
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 MEF2A MEF2C

6.34e-04193393697518bab1338dc441b2d93b410d957e692f20e6
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL HAGH

6.34e-0419339355eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B IFT172 PGAP1

6.43e-0419439346e522ca59db545d1eb0c27cd4361f19d4f8f762
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

TSPAN12 EFHD1 MEF2C

6.43e-041943933892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCelldroplet-Fat-Mat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL RYR2

6.43e-0419439374d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCellDiffer-Basal|World / shred by cell class for mouse tongue

TSPAN12 MGLL HAGH

6.43e-04194393851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCellPBMC-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

MEF2A MEF2C HERC5

6.53e-04195393674355ca00314bde90ef7f6ddb83afe2d5323130
ToppCellfacs-Aorta-Heart-3m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL MEF2A

6.53e-041953938493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGLL GLOD4 LIMD1

6.53e-041953931e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 SGPL1 PGAP1

6.53e-04195393d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

MGLL MEF2A MEF2C

6.53e-0419539350a193475db1bb1e05b8590225a553688c372c14
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MEF2A MEF2C

6.53e-041953933969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B IFT172 PGAP1

6.53e-04195393b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCellsevere-Lymphocytic-Plasmablast|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGLL AARS1 MEF2C

6.53e-0419539343ff1eed563c647bc5b7b06ffe136210653c3a83
ToppCellfacs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 MGLL MEF2A

6.53e-041953935e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGLL MEF2A MEF2C

6.53e-04195393a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B IFT172 PGAP1

6.63e-0419639397324c9e93f833e1f218e81fb53066d44c6892df
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM3B MAOA PGAP1

6.63e-04196393055993612af03bff5ef73580a6402578da850df9
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MGLL PELO MEF2C

6.63e-0419639340cae477b3906623d1f2a4c630279e710499ce80
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MGLL EFHD1 MEF2C

6.63e-041963931d94cecd378a829dd8014fc086d7fca48c953a91
ToppCellSkin-Tubules|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

TSPAN12 MEF2B RYR2

6.63e-0419639312e21cc310a261407b46e034108e8c93ea16e045
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MGLL EFHD1 MEF2C

6.63e-04196393aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell(4)_Endothelial_cells-(41)_EC-arteriolar|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

TSPAN12 MGLL EFHD1

6.73e-04197393482e3f8926880afed88ed37553ed2b5ed58b8c99
DrugMetformin

TSPAN12 AARS1 MEF2B MEF2A MEF2C MEF2D CTDP1

4.64e-06400397ctd:D008687
Diseaseintellectual disability (implicated_via_orthology)

MEF2B MEF2A MEF2C MEF2D

2.96e-0675394DOID:1059 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

MEF2A MEF2C MEF2D

6.83e-0628393DOID:1094 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

MEF2B MEF2A MEF2C MEF2D

4.84e-05152394DOID:0060041 (implicated_via_orthology)
Diseasedisks large homolog 3 measurement

MEF2C MEF2D

1.11e-0412392EFO_0802472
Diseasenoggin measurement

MEF2C MEF2D

2.57e-0418392EFO_0021995
DiseasePsychotic Disorders

MAOA MEF2A PICK1

3.25e-04101393C0033975
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

AARS1 SGPL1

4.61e-0424392DOID:10595 (implicated_via_orthology)
DiseaseEndometrioma

MTA2 MAOA HERC5

1.26e-03161393C0269102
DiseaseEndometriosis

MTA2 MAOA HERC5

1.26e-03161393C0014175
Diseasecongestive heart failure (implicated_via_orthology)

TOMM70 RYR2

1.35e-0341392DOID:6000 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease

AARS1 SGPL1

1.42e-0342392cv:C0007959
DiseaseCCL5 measurement

KCNA4 MEF2C

3.26e-0364392EFO_0005117
DiseaseNonorganic psychosis

MEF2A PICK1

3.78e-0369392C0349204

Protein segments in the cluster

PeptideGeneStartEntry
VMFDFLDCVADLKGK

PPP2R5B

86

Q15173
LYTLCKEDLESMDKE

CTDP1

846

Q9Y5B0
AKYLLADCSEAFLKM

RAD21L1

71

Q9H4I0
EAEKLSADCGMKYIE

RAB39A

141

Q14964
SEAMLFEEALEKYGK

MTA2

271

O94776
FCYKAILEFAEKEGM

PTPN9

566

P43378
KKKDYCGCMIIEDED

MAOA

316

P21397
MDKYDDLGLEASKFI

LIMD1

1

Q9UGP4
LCDSKGAYLLMELAK

MGLL

241

Q99685
CNLLGMKIYEKDEEK

GLOD4

171

Q9HC38
KFYEGTADEMCKALL

HAGH

191

Q16775
LDDDYNGQAKCMLEK

PDE7A

136

Q13946
VKMFEDKGLDCIFLE

CWF19L2

741

Q2TBE0
FGLMKKAYELSVLCD

MEF2C

26

Q06413
FGLMKKAYELSVLCD

MEF2A

26

Q02078
EYDLLCKIMGETFKK

HECTD4

936

Q9Y4D8
KYAKICFEDNLLMGE

FAM3B

86

P58499
FGLMKKAYELSVLCD

MEF2B

26

Q02080
LKYAMFLEDEGKFEE

IFT172

1146

Q9UG01
RGFYKMCDEDIIKLF

HERC5

886

Q9UII4
YEDCKDLIKSMLRDE

NBPF3

116

Q9H094
LIKDLESMFKLYDAG

EFHD1

91

Q9BUP0
LTEKCKLEEDFLYMA

RYR2

3676

Q92736
FGLMKKAYELSVLCD

MEF2D

26

Q14814
GEDDDCRYVMIFKKE

SPAG7

96

O75391
GCCLEYATMLDKEAK

PGAP1

621

Q75T13
AAGEVKALDDFYKML

PELO

271

Q9BRX2
MACKAYRDLAFEKGI

SGPL1

216

O95470
FLRGSLEEKMKYCFE

CLXN

96

Q9HAE3
KEEISRYCGKEKDLM

TXNDC16

86

Q9P2K2
FGDYFKELACKMALE

AARS1

106

P49588
FDLLLDAEKCKYGME

POLR2A

1471

P24928
EKCDSYKDDLLLRMG

POLK

6

Q9UBT6
GYELAADKKMCEVAC

TLL2

606

Q9Y6L7
QFGKADEMYDKCIDL

TOMM70

491

O94826
EDLSDLYQEGCGKKM

TSPAN12

196

O95859
YDAFSILDMLKLEGK

UGGT2

391

Q9NYU1
LSYCLKVKEMDDEEY

PICK1

261

Q9NRD5
YLEMEEGVKESLCAK

KCNA4

611

P22459