Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

NOC2L TRMT112 KMT2A USP21

4.37e-0565624GO:0045815
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

NOC2L TRMT112 KMT2A USP21

5.22e-0568624GO:0141137
DomainTMEM191C

TMEM191B TMEM191C

1.12e-052632PF15194
DomainTMEM191B/C

TMEM191B TMEM191C

1.12e-052632IPR028186
DomainGREB1

GREB1L GREB1

1.12e-052632PF15782
DomainGREB1

GREB1L GREB1

1.12e-052632IPR028422
DomainVWFC_1

AMN CHRD CHRDL1

2.41e-0436633PS01208
DomainVWFC_2

AMN CHRD CHRDL1

2.84e-0438633PS50184
DomainVWF_dom

AMN CHRD CHRDL1

3.82e-0442633IPR001007
DomainVWC

CHRD CHRDL1

4.00e-0328632PF00093
DomainKazal_2

SLCO2A1 SMOC1

6.55e-0336632PF07648
DomainVWC

CHRD CHRDL1

7.28e-0338632SM00214
Pubmed

Neuralin-1 is a novel Chordin-related molecule expressed in the mouse neural plate.

CHRD CHRDL1

3.55e-06266211118896
Pubmed

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.

GREB1L GREB1

3.55e-06266229100090
Pubmed

A novel chordin-like protein inhibitor for bone morphogenetic proteins expressed preferentially in mesenchymal cell lineages.

CHRD CHRDL1

3.55e-06266211401399
Pubmed

The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort.

PRSS56 MYRF

3.55e-06266232052405
Pubmed

A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans.

GREB1L GREB1

3.55e-06266228739660
Pubmed

Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study.

PRSS56 MYRF

1.06e-05366231266062
Pubmed

Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism.

AMHR2 PRPH

2.12e-05466231291191
Pubmed

Redox regulation of ERK1/2 activation induced by sphingosine 1-phosphate in fibroblasts: involvement of NADPH oxidase and platelet-derived growth factor receptor.

PDGFRB S1PR2

3.53e-05566221256191
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

LETMD1 NDUFS7 MED16 TRMT112 SMPD4 TRRAP CCDC61 TUFM DDX6 PRPH

3.54e-051082661038697112
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF219 NDUFS7 ARHGAP23 ERC1 PRSS56 GPATCH2 SIPA1 PLEKHN1 TRRAP TUFM

4.59e-051116661031753913
Pubmed

Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice.

GREB1L GREB1

5.29e-05666229100091
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ULK3 CLPB ARHGAP23 MED16 GPATCH2 KMT2A TRRAP PDE7B DDX6

5.38e-0591066936736316
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NDUFS7 ACADL ARHGAP23 ARVCF ERC1 CNTNAP1 KMT2A SIPA1 NDUFB5 TUFM DDX6

7.38e-051431661137142655
Pubmed

SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation.

KMT2A TRRAP

7.40e-05766219818711
Pubmed

In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus.

AMHR2 PDGFRB

9.86e-05866232402291
Pubmed

Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation.

CHRD CHRDL1

9.86e-05866218789316
Pubmed

The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development.

PDGFRB S1PR2

9.86e-05866225377550
Pubmed

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.

ROBO2 PRPH

9.86e-05866222912413
Pubmed

Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.

NDUFS7 ARHGAP23 ERC1

1.13e-044966331609468
Pubmed

Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.

PDGFRB ROBO2

1.58e-041066222840396
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CLPB MED16 NOC2L GPATCH2 TRRAP DDX6

1.90e-0444066634244565
Pubmed

The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs.

ROBO2 PRPH

1.93e-041166228970231
Pubmed

Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell Formation, and GnRH-1 Neuronal Migration.

ROBO2 PRPH

2.31e-041266231767679
Pubmed

Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells.

CNTNAP1 PRPH

2.73e-041366220830809
Pubmed

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.

KMT2A TRRAP

2.73e-041366216510874
Pubmed

Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.

ERC1 GPR179

2.73e-041366236179691
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

CCDC14 ULK3 ROBO2 S1PR2 SMOC1

2.77e-0430266530561431
Pubmed

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.

MED16 TRRAP

3.67e-041566218418385
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

KMT2A TRRAP

3.67e-041566216510875
Pubmed

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.

CHRD CHRDL1

4.74e-041766217693602
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

GREB1L NDUFS7 CLPB MED16 NOC2L TPP1 KMT2A TRRAP TUFM DDX6

4.96e-041497661031527615
Pubmed

The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.

KMT2A DDX6

5.32e-041866221030982
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

NDUFS7 ACADL TPP1 DGUOK NDUFB5 TUFM

5.74e-0454266614651853
Pubmed

Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication.

SMPD4 TUFM

5.94e-041966236952345
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

ULK3 AMHR2 CLPB TTC4 DDX6

6.39e-0436366525036637
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

NEU4 LETMD1 NDUFS7 ACADL CLPB DGUOK NDUFB5 TUFM

8.05e-04104766818614015
Pubmed

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.

CHRD CHRDL1

9.53e-042466236916392
Pubmed

Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells.

PDGFRB PRSS56

9.53e-042466230348676
Pubmed

Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.

ROBO2 PRPH

1.03e-032566215229182
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

GPR179 PRPH

1.03e-032566235681537
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

NDUFS7 TPP1 CNTNAP1 TTC4 TUFM DDX6

1.09e-0361366622268729
Pubmed

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing.

CHRD DDX6

1.21e-032766236197846
Pubmed

The protein kinase complement of the human genome.

ULK3 SBK2

1.30e-032866212471243
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

CHRD CHRDL1

1.30e-032866223103586
Pubmed

Proteomic profiling of Myc-associated proteins.

ERC1 ROBO2 TRRAP

1.35e-0311466321150319
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

GREB1L GREB1

1.49e-033066229555813
Pubmed

Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.

DGUOK GPATCH2

1.70e-033266221546767
Pubmed

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

ARHGAP23 GPR179

1.70e-033266223535730
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

LETMD1 NDUFS7 ACADL CLPB DGUOK NDUFB5 TUFM

1.85e-0392666720877624
Cytoband19q13.32

CEACAM16 SIX5 CCDC61

1.71e-047466319q13.32
Cytoband22q11.21

ARVCF TMEM191B TMEM191C

5.63e-0411166322q11.21
CytobandEnsembl 112 genes in cytogenetic band chr2p25

ALLC DCDC2C GREB1

8.33e-04127663chr2p25
Cytoband12q13.12

LETMD1 DDN

1.38e-033866212q13.12
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGFALS ARHGAP23 TPP1 CHRDL1 SIX5

3.77e-061586651635a85fc73c544028418087f36d28957dd4f458
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGFALS ARHGAP23 TPP1 CHRDL1 SIX5

3.77e-0615866580841dadfa53bcde36a3e486408a095f78e772eb
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRB SLCO2A1 DDN ROBO2 GREB1

5.70e-06172665073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AMHR2 PLPPR3 PLEKHN1 MYRF SBK2

8.78e-061886656151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

ALLC SLCO2A1 ST6GAL1 SMOC1 PDE7B

9.97e-061936652531266bc57339d4e2b22a88817008e32b8c1598
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

C19orf81 PDGFRB CHRDL1 ROBO2 PDE7B

1.16e-051996656b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGFALS ARHGAP23 CHRDL1 SIX5

4.17e-0513066492913960e4367261ba08a405b61a421bc5e18169
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB CHRDL1 ROBO2 PDE7B

9.58e-051616641b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

ZNF341 TMEM191C PLEKHN1 SIGLEC15

1.08e-041666644ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 PDGFRB SLCO2A1 DDN

1.15e-0416966487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PDGFRB DDN ROBO2

1.24e-041726646c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2C PDGFRB CHRDL1 SMOC1

1.32e-04175664795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

DCDC2C CHRDL1 SMOC1 PDE7B

1.44e-04179664411620201a860716a8773b92f50f7b94ef34a586
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRB DDN ST6GAL1 GPR179

1.44e-041796647078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRB DDN ST6GAL1 GPR179

1.44e-04179664d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-1|TCGA-Uvea / Sample_Type by Project: Shred V9

NDUFS7 MED16 TPP1 TUFM

1.47e-041806648f18701fd6e0cc35ed175814e2377d93720c1481
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRB CHRD CHRDL1 ROBO2

1.50e-04181664b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

PDGFRB CHRDL1 MYRF PRPH

1.54e-04182664354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L ERC1 ROBO2 ST6GAL1

1.57e-04183664b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PDGFRB DDN ROBO2

1.57e-04183664848fc6dd129150897ee339343e83c645b6e779eb
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

PDGFRB CHRD CHRDL1 ROBO2

1.60e-0418466486a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRB CNTNAP1 DDN ROBO2

1.60e-041846641c857126c0ea0671f0d60b048efca288d348d653
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDGFRB CHRDL1 ROBO2 PDE7B

1.63e-041856643b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellwk_15-18-Mesenchymal-Mesothelial-Early_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AMHR2 PLEKHN1 MYRF SBK2

1.67e-04186664ae4b6ecfc1850c0a01a11b9dd9718880f2a24fe0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GREB1L ACADL CA13 CHRDL1

1.67e-0418666477592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

ALLC SLCO2A1 ST6GAL1 SMOC1

1.70e-041876647876dcb4800c2e54874df3d933efb79307a64a97
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ALLC PDGFRB ROBO2 SMOC1

1.74e-04188664ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB CNTNAP1 CHRDL1 PDE7B

1.74e-0418866432f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L ERC1 ROBO2 ST6GAL1

1.77e-04189664fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

SLCO2A1 ST6GAL1 SMOC1 PDE7B

1.77e-0418966475c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

SLCO2A1 ST6GAL1 SMOC1 PDE7B

1.77e-04189664c81787a8c662db5d7814c583dd64562857629e81
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLCO2A1 ST6GAL1 SMOC1 PDE7B

1.77e-041896647346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellwk_08-11-Epithelial-PNS-Early_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PRSS56 CA13 SMOC1 SIPA1

1.81e-041906648190674a48607984726974765aafbca116f437e0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a6-Slc17a7-Slc17a8.Fezf2.Slc17a8_(Deep_layer_pyramidal_cells-Layer_5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NUTM1 DCDC2C SIGLEC15

1.81e-0474663e6c8b8046948a205e996e585f983fd0af80d5491
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AMHR2 PLEKHN1 MYRF SBK2

1.85e-04191664b5374674312ff5803a1d369f5533027532344679
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

SLCO2A1 ST6GAL1 SMOC1 PDE7B

1.88e-04192664c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellproximal-Hematologic-Platelet/Megakaryocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN CLPB WDR97 SMPD4

1.88e-04192664522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L ERC1 ROBO2 MYRF

1.88e-041926640bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellproximal-Hematologic-Platelet/Megakaryocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN CLPB WDR97 SMPD4

1.88e-0419266457899a905ca3e336bb7f31edc6418a2546b9891a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 SLCO2A1 MYRF PDE7B

1.88e-041926642510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellproximal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN CLPB WDR97 SMPD4

1.88e-04192664f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 SLCO2A1 MYRF PDE7B

1.88e-04192664e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

SLCO2A1 ST6GAL1 SMOC1 PDE7B

1.92e-0419366401c2df9206f1527c578e808978e58196c35e72f5
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DCDC2C ARHGAP23 SMOC1 PDE7B

1.96e-04194664f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

ALLC SLCO2A1 ST6GAL1 SMOC1

1.96e-04194664b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DCDC2C ARHGAP23 SMOC1 PDE7B

1.96e-041946645d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DCDC2C ARHGAP23 SMOC1 PDE7B

1.96e-041946643b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DCDC2C CHRDL1 SMOC1 PDE7B

2.00e-04195664de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellwk_08-11-Mesenchymal-Mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AMHR2 PLEKHN1 MYRF SBK2

2.00e-041956649016a44b521214546a55a822ebdef5b5312206d2
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GREB1L C19orf81 IGFALS MYRF

2.08e-0419766449689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRB CHRD CHRDL1 GREB1

2.08e-0419766471786e9432e2d649f5d86f639abb25e7102deb67
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRB PRSS56 CHRD PRPH

2.08e-041976643f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP1 CHRDL1 SIX5 SIPA1

2.16e-04199664a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDGFRB CHRDL1 ROBO2 PDE7B

2.16e-0419966438cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDGFRB CHRDL1 ROBO2 PDE7B

2.20e-0420066467dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PDGFRB CHRDL1 ROBO2 PDE7B

2.20e-04200664a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDGFRB CHRDL1 ROBO2 PDE7B

2.20e-04200664f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDGFRB CHRDL1 ROBO2 PDE7B

2.20e-0420066409537dc25f8b8b4654a7c183827ee1522a41a4e0
DiseaseMicrophthalmos

PRSS56 MYRF

2.44e-0411632C0026010
Diseasesensory peripheral neuropathy, remission

DCDC2C KMT2A

1.10e-0323632EFO_0009785, MONDO_0002321

Protein segments in the cluster

PeptideGeneStartEntry
RIGRSGRFGHLGLAI

DDX6

421

P26196
SESLSRGGHRRRGKP

CCDC61

431

Q9Y6R9
LLTAPRFARLHGISG

CNTNAP1

46

P78357
HFLLRGGGPVATLSR

ARVCF

166

O00192
LRGSLRVLGGHRAPR

ACADL

6

P28330
GGVSRLRLRGFPSSI

ALLC

356

Q8N6M5
RLGLSPDGRVLARHG

CEACAM16

176

Q2WEN9
VSSSRGLHAGRGPRR

DGUOK

26

Q16854
IRPHTFTGLSGLRRL

IGFALS

401

P35858
RAGRLRFHGPGALSV

AMN

186

Q9BXJ7
RGGPLTGSYRLRQVH

CA13

81

Q8N1Q1
HLLLRGSAGTAPRRR

DDN

206

O94850
RSGARPGQVLSSGRH

CCDC14

51

Q49A88
HIVRFITASRGGPGR

AMHR2

256

Q16671
RSPRLGHRRTNSTGG

ERC1

26

Q8IUD2
SRLLRSGLSPRGLAH

C19orf81

146

C9J6K1
SSGPFLGLRLVTRGR

LDLRAD2

141

Q5SZI1
GHFVTRRLQLGRSGL

LETMD1

21

Q6P1Q0
GRVDGFHPRRLLLSG

GREB1

1331

Q4ZG55
PGHGSLPGSSRRRLL

GPR179

741

Q6PRD1
RLGSFRSPRAGAGAL

PRPH

56

P41219
LLPRQHRSRGSSGSG

PDE7B

416

Q9NP56
LLRATPHFSGLAAGR

TUFM

6

P49411
AHRLVLRRGTLAGGS

NEU4

51

Q8WWR8
SGTRNFHPRRLLLTG

GREB1L

1306

Q9C091
FSERGILRPLSTRHG

NOC2L

681

Q9Y3T9
GHTRGPRLSLRFLGS

SMPD4

801

Q9NXE4
GSLLRPGHSFLRDGT

MED16

636

Q9Y2X0
SHQGLGSTLPRRGTR

NUTM1

966

Q86Y26
GLSRFPGARSHRGAL

CHRDL1

221

Q9BU40
RRLFTPTRGHRVLGL

DCDC2C

61

A8MYV0
PLLSSGLRSIGSRRH

KMT2A

2181

Q03164
LRSPTLRGHGGASGR

CLPB

21

Q9H078
PSRRGFQARLSRLHG

GPATCH2

336

Q9NW75
RRGGTPGHHLLPLRS

S1PR2

316

O95136
LTDFGHTRPRGTLLR

SBK2

201

P0C263
LRSQARLPGFHGLRS

PDGFRB

986

P09619
LRLHSGSRAAGTRFP

PRSS56

446

P0CW18
TALSLHGRFRLLGNP

SIGLEC15

106

Q6ZMC9
RLTRLRTASGHEPGG

PLEKHN1

206

Q494U1
RRLGPRGGRHLGSVS

TMEM191B

31

P0C7N4
RRLGPRGGRHLGSVS

TMEM191C

31

A6NGB0
AGHAGRLSRFLGALP

SIX5

101

Q8N196
SASRFGLPSLGGRRR

SIPA1

551

Q96FS4
PHRGRQTLGSLRGLA

ST6GAL1

71

P15907
APGLRGFRILGLRSS

NDUFS7

6

O75251
AGRPGLRISGHIAAR

CHRD

386

Q9H2X0
FGSRVHRPRLIGIGG

SLCO2A1

91

Q92959
LSPARGHRTTGPRFL

SMOC1

21

Q9H4F8
LRRHLPTHGSGGRFK

ZNF341

581

Q9BYN7
LRRSTSLRRLGGFPG

USP21

151

Q9UK80
SRESTLRRHAGGLGL

PLPPR3

681

Q6T4P5
SHVRGVGSRGFPLRL

TRMT112

11

Q9UI30
RSGGRRLVLRGSALH

WDR97

226

A6NE52
GPGGRLTRRPSFSSH

ARHGAP23

1296

Q9P227
RPLGTRLGFGGFLTR

NDUFB5

21

O43674
PSGSLFFLRIVHGRR

ROBO2

86

Q9HCK4
GRALSSPGSLGRHLL

ZNF821

156

O75541
PHGARLSLDGQGRLS

TTC4

261

O95801
GRGGPGRSLLHRHLF

WWC2-AS2

111

Q96NR7
RALFRSIGGGSHDLL

TRRAP

761

Q9Y4A5
ARGRSLGSLASLHPR

ZNF219

441

Q9P2Y4
PGGLRRSLLLHGARS

ZNF282

501

Q9UDV7
GGDLSRFIHTRRILP

ULK3

96

Q6PHR2
GGLHRFPPTSSLRQR

TPP1

171

O14773
PSLGFHGRARRGALQ

MYRF

976

Q9Y2G1