Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	ATP8B3 ABCC3 ATP8B4 TMEM120A CLCN7 SLC15A2 SLC17A1 ABCA12 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 SLC16A7 MFSD12 RYR2 CHRNB4 ITPR1 TPCN1	6.37e-07	1289	96	21	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCC3 TMEM120A CLCN7 SLC15A2 SLC17A1 ABCA12 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 SLC16A7 MFSD12 RYR2 CHRNB4 ITPR1 TPCN1	2.86e-06	1180	96	19	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TMEM120A CLCN7 SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 CHRNB4 ITPR1 TPCN1	5.52e-06	793	96	15	GO:0015075
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	GRIN2A RYR2 ITPR1 TPCN1	1.43e-05	31	96	4	GO:0099604
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	1.44e-05	465	96	11	GO:0046873
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ABCC3 CLCN7 SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	1.53e-05	758	96	14	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 CHRNB4 ITPR1 TPCN1	1.73e-05	664	96	13	GO:0008324
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR52B4 OR51B5 OR11L1 TAS2R16 CELSR1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 TAS2R39 OR5M3 TAS2R19 OR52Z1P	2.00e-05	884	96	15	GO:0004930
GeneOntologyMolecularFunction	gated channel activity	CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	3.33e-05	334	96	9	GO:0022836
GeneOntologyMolecularFunction	channel activity	TMEM120A CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A SLC12A7 RYR2 CHRNB4 ITPR1 TPCN1	4.39e-05	525	96	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TMEM120A CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A SLC12A7 RYR2 CHRNB4 ITPR1 TPCN1	4.46e-05	526	96	11	GO:0022803
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	4.66e-05	627	96	12	GO:0022890
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNJ16 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	5.89e-05	140	96	6	GO:0099094
GeneOntologyMolecularFunction	G protein-coupled UTP receptor activity	P2RY2 P2RY4	6.84e-05	3	96	2	GO:0045030
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	MRC1 OR52B4 OR51B5 OR11L1 TAS2R16 CELSR1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 TAS2R39 GRIN2A OR5M3 TAS2R19 OR52Z1P CHRNB4	6.99e-05	1353	96	18	GO:0004888
GeneOntologyMolecularFunction	monoatomic ion channel activity	TMEM120A CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	7.21e-05	459	96	10	GO:0005216
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR2 ITPR1 TPCN1	8.34e-05	18	96	3	GO:0015278
GeneOntologyMolecularFunction	symporter activity	SLC15A2 SLC17A1 SLC4A4 SLC12A7 SLC16A7 MFSD12	8.64e-05	150	96	6	GO:0015293
GeneOntologyMolecularFunction	G protein-coupled pyrimidinergic nucleotide receptor activity	P2RY2 P2RY4	1.36e-04	4	96	2	GO:0071553
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNJ16 SCN10A CATSPER3 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	2.49e-04	343	96	8	GO:0005261
GeneOntologyMolecularFunction	voltage-gated channel activity	CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A TPCN1	2.63e-04	184	96	6	GO:0022832
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R16 TAS2R39 TAS2R19	2.90e-04	27	96	3	GO:0033038
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B3 ATP8B4 ABCA12	3.23e-04	28	96	3	GO:0140326
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	KCNJ16 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	3.40e-04	193	96	6	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	KCNJ16 GRIN2A RYR2 CHRNB4 ITPR1 TPCN1	3.79e-04	197	96	6	GO:0022834
GeneOntologyMolecularFunction	calcium channel activity	CATSPER3 GRIN2A RYR2 ITPR1 TPCN1	3.98e-04	129	96	5	GO:0005262
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC3 CLCN7 SLC15A2 SLC17A1 ABCA12 SLC4A4 SLC12A7 SLC16A7 MFSD12	4.84e-04	477	96	9	GO:0022804
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR2 ITPR1 TPCN1	5.29e-04	33	96	3	GO:0005217
GeneOntologyMolecularFunction	taste receptor activity	TAS2R16 TAS2R39 TAS2R19	5.29e-04	33	96	3	GO:0008527
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	CLCN7 SLC15A2 SLC17A1 SLC4A4 SLC12A7 SLC16A7 MFSD12	5.67e-04	296	96	7	GO:0015291
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC3 ABCA12	8.06e-04	9	96	2	GO:0034040
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CATSPER3 GRIN2A RYR2 ITPR1 TPCN1	8.14e-04	151	96	5	GO:0015085
GeneOntologyMolecularFunction	G-quadruplex RNA binding	DHX36 PATL2	1.00e-03	10	96	2	GO:0002151
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	ABCC3 CLCN7 SLC17A1 SLC4A4 SLC12A7	1.42e-03	171	96	5	GO:0015103
GeneOntologyMolecularFunction	G protein-coupled purinergic nucleotide receptor activity	P2RY2 P2RY4	1.72e-03	13	96	2	GO:0045028
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A	1.86e-03	182	96	5	GO:0005244
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B3 ATP8B4 ABCA12	1.90e-03	51	96	3	GO:0140303
GeneOntologyMolecularFunction	GTPase activator activity	EVI5 ARHGAP40 RABGAP1L RABGAP1 ARHGAP20 EVI5L	2.29e-03	279	96	6	GO:0005096
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC15A2 SLC17A1 SLC4A4 SLC12A7	2.61e-03	119	96	4	GO:0015294
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH17	3.33e-03	18	96	2	GO:0008569
GeneOntologyMolecularFunction	olfactory receptor activity	OR52B4 OR51B5 OR11L1 OR7D2 OR6Y1 OR5M3 OR52Z1P	4.77e-03	431	96	7	GO:0004984
GeneOntologyMolecularFunction	nucleotide receptor activity	P2RY2 P2RY4	4.96e-03	22	96	2	GO:0016502
GeneOntologyMolecularFunction	purinergic nucleotide receptor activity	P2RY2 P2RY4	4.96e-03	22	96	2	GO:0001614
GeneOntologyBiologicalProcess	detection of stimulus	OR52B4 OR51B5 OR11L1 CDS1 TAS2R16 EYS TMEM120A HTR2A HLA-A OR7D2 SCN10A OR6Y1 TAS2R39 GRIN2A OR5M3 TAS2R19 OR52Z1P RYR2	3.14e-09	722	93	18	GO:0051606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR52B4 OR51B5 OR11L1 TAS2R16 EYS TMEM120A HTR2A OR7D2 SCN10A OR6Y1 TAS2R39 GRIN2A OR5M3 TAS2R19 OR52Z1P	4.91e-08	582	93	15	GO:0050906
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	ABCC3 IBTK TMEM120A HTR2A CLCN7 SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 CHRNB4 ITPR1 TPCN1	2.09e-06	1115	93	18	GO:0034220
GeneOntologyBiologicalProcess	sensory perception	OR52B4 OR51B5 OR11L1 TAS2R16 EYS NPY1R TMEM120A HTR2A OR7D2 SCN10A OR6Y1 TAS2R39 GRIN2A OR5M3 TAS2R19 OR52Z1P USH2A	5.31e-06	1072	93	17	GO:0007600
GeneOntologyBiologicalProcess	monoatomic ion transport	ABCC3 IBTK TMEM120A HTR2A CLCN7 SLC15A2 P2RY4 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 CHRNB4 ITPR1 TPCN1	9.87e-06	1374	93	19	GO:0006811
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR52B4 OR51B5 OR11L1 TAS2R16 OR7D2 OR6Y1 TAS2R39 OR5M3 TAS2R19 OR52Z1P RYR2	2.38e-05	524	93	11	GO:0009593
GeneOntologyBiologicalProcess	transepithelial transport	GPLD1 CLCN7 P2RY4 ITPR1	2.54e-05	38	93	4	GO:0070633
GeneOntologyBiologicalProcess	regulation of cytosolic calcium ion concentration	NPY1R P2RY2 P2RY4 RYR2 ITPR1	3.90e-05	84	93	5	GO:0051480
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception of pain	TMEM120A HTR2A SCN10A GRIN2A	4.18e-05	43	93	4	GO:0062149
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	IBTK HTR2A CLCN7 SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	4.72e-05	1017	93	15	GO:0098660
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	IBTK HTR2A SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	6.37e-05	922	93	14	GO:0098662
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR52B4 OR51B5 OR11L1 TAS2R16 OR7D2 OR6Y1 TAS2R39 OR5M3 TAS2R19 OR52Z1P	6.65e-05	485	93	10	GO:0050907
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	IBTK HTR2A SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	8.01e-05	942	93	14	GO:0098655
GeneOntologyBiologicalProcess	sensory perception of pain	NPY1R TMEM120A HTR2A SCN10A GRIN2A	1.13e-04	105	93	5	GO:0019233
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	TMEM120A HTR2A SCN10A GRIN2A	1.27e-04	57	93	4	GO:0050974
GeneOntologyBiologicalProcess	detection of external stimulus	CDS1 EYS TMEM120A HTR2A SCN10A GRIN2A	1.33e-04	173	93	6	GO:0009581
GeneOntologyBiologicalProcess	detection of abiotic stimulus	CDS1 EYS TMEM120A HTR2A SCN10A GRIN2A	1.42e-04	175	93	6	GO:0009582
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR52B4 OR51B5 OR11L1 TAS2R16 OR7D2 OR6Y1 TAS2R39 OR5M3 TAS2R19 OR52Z1P	1.78e-04	547	93	10	GO:0007606
GeneOntologyBiologicalProcess	monoatomic anion transport	ABCC3 CLCN7 P2RY4 SLC17A1 SLC4A4 SLC12A7	1.81e-04	183	93	6	GO:0006820
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of pain	TMEM120A HTR2A GRIN2A	2.14e-04	26	93	3	GO:0050966
GeneOntologyBiologicalProcess	regulation of presynaptic cytosolic calcium ion concentration	NPY1R P2RY2 P2RY4	2.14e-04	26	93	3	GO:0099509
GeneOntologyBiologicalProcess	detection of mechanical stimulus	TMEM120A HTR2A SCN10A GRIN2A	3.69e-04	75	93	4	GO:0050982
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR52B4 OR51B5 OR11L1 TAS2R16 CELSR1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 TAS2R39 OR5M3 TAS2R19 OR52Z1P ITPR1	4.71e-04	1395	93	16	GO:0007186
GeneOntologyBiologicalProcess	metal ion transport	IBTK HTR2A SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	5.36e-04	1000	93	13	GO:0030001
GeneOntologyBiologicalProcess	transport across blood-brain barrier	ABCC3 SLC15A2 SLC4A4 SLC16A7	6.48e-04	87	93	4	GO:0150104
GeneOntologyBiologicalProcess	monoatomic cation transport	IBTK HTR2A SLC15A2 SLC17A1 KCNJ16 SCN10A CATSPER3 GRIN2A SLC4A4 SLC12A7 ZDHHC13 RYR2 ITPR1 TPCN1	6.58e-04	1157	93	14	GO:0006812
GeneOntologyBiologicalProcess	vascular transport	ABCC3 SLC15A2 SLC4A4 SLC16A7	6.76e-04	88	93	4	GO:0010232
GeneOntologyCellularComponent	transporter complex	ATP8B3 ATP8B4 CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A RYR2 CHRNB4 TPCN1	1.83e-04	550	94	10	GO:1990351
GeneOntologyCellularComponent	monoatomic ion channel complex	CLCN7 KCNJ16 SCN10A CATSPER3 GRIN2A RYR2 CHRNB4 TPCN1	3.05e-04	378	94	8	GO:0034702
GeneOntologyCellularComponent	nuclear RNA export factor complex	NXF5 NXF3	4.14e-04	7	94	2	GO:0042272
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	GLIPR1 ATP8B3 MRC1 ATP8B4 HLA-A SLC15A2 ABCA12 IZUMO1 CD274 GRIN2A ZDHHC13 MFSD12 CHRNB4 ITPR1 TPCN1	7.03e-04	1307	94	15	GO:0030659
GeneOntologyCellularComponent	secretory granule membrane	GLIPR1 ATP8B3 ATP8B4 ABCA12 IZUMO1 CHRNB4 ITPR1	7.12e-04	329	94	7	GO:0030667
GeneOntologyCellularComponent	vesicle membrane	GLIPR1 ATP8B3 MRC1 ATP8B4 HLA-A SLC15A2 ABCA12 IZUMO1 CD274 GRIN2A ZDHHC13 MFSD12 CHRNB4 ITPR1 TPCN1	8.09e-04	1325	94	15	GO:0012506
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ATP8B3 CDS1 TMEM53 HLA-A TMEM259 PARP16 IZUMO1 HACD4 CERS6 GRIN2A ELOVL6 RNF133 RYR2 STT3A ITPR1	8.21e-04	1327	94	15	GO:0042175
GeneOntologyCellularComponent	cell body fiber	HTR2A SACS	1.07e-03	11	94	2	GO:0070852
GeneOntologyCellularComponent	synaptic membrane	NPY1R HTR2A P2RY2 P2RY4 SCN10A GRIN2A SLC16A7 CHRNB4 ITPR1	1.24e-03	583	94	9	GO:0097060
GeneOntologyCellularComponent	presynaptic membrane	NPY1R HTR2A P2RY2 P2RY4 SCN10A GRIN2A	1.58e-03	277	94	6	GO:0042734
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8B3 ATP8B4	1.76e-03	14	94	2	GO:1990531
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ATP8B3 CDS1 HLA-A TMEM259 PARP16 IZUMO1 HACD4 CERS6 GRIN2A ELOVL6 RNF133 RYR2 STT3A ITPR1	1.87e-03	1293	94	14	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ATP8B3 CDS1 HLA-A TMEM259 PARP16 IZUMO1 HACD4 CERS6 GRIN2A ELOVL6 RNF133 RYR2 STT3A ITPR1	1.95e-03	1299	94	14	GO:0098827
Domain	NXF_fam	NXF5 NXF3	6.72e-05	3	89	2	IPR030217
Domain	TBC	EVI5 RABGAP1L RABGAP1 EVI5L	8.66e-05	49	89	4	SM00164
Domain	RabGAP-TBC	EVI5 RABGAP1L RABGAP1 EVI5L	1.18e-04	53	89	4	PF00566
Domain	Tap-RNA_bind	NXF5 NXF3	1.34e-04	4	89	2	PF09162
Domain	Tap_RNA_bd	NXF5 NXF3	1.34e-04	4	89	2	PD043466
Domain	Tap_RNA-bd	NXF5 NXF3	1.34e-04	4	89	2	IPR015245
Domain	TBC_RABGAP	EVI5 RABGAP1L RABGAP1 EVI5L	1.36e-04	55	89	4	PS50086
Domain	Rab-GTPase-TBC_dom	EVI5 RABGAP1L RABGAP1 EVI5L	1.36e-04	55	89	4	IPR000195
Domain	Ion_trans_dom	SCN10A CATSPER3 RYR2 ITPR1 TPCN1	2.14e-04	114	89	5	IPR005821
Domain	Ion_trans	SCN10A CATSPER3 RYR2 ITPR1 TPCN1	2.14e-04	114	89	5	PF00520
Domain	TAS2R	TAS2R16 TAS2R39 TAS2R19	2.51e-04	26	89	3	PF05296
Domain	T2R	TAS2R16 TAS2R39 TAS2R19	2.51e-04	26	89	3	IPR007960
Domain	RIH_assoc	RYR2 ITPR1	3.33e-04	6	89	2	PF08454
Domain	RIH_assoc-dom	RYR2 ITPR1	3.33e-04	6	89	2	IPR013662
Domain	RIH_dom	RYR2 ITPR1	3.33e-04	6	89	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR1	3.33e-04	6	89	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR1	3.33e-04	6	89	2	IPR015925
Domain	-	RYR2 ITPR1	3.33e-04	6	89	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR1	3.33e-04	6	89	2	PF01365
Domain	DUF3694	RABGAP1L RABGAP1	3.33e-04	6	89	2	PF12473
Domain	Ins145_P3_rec	RYR2 ITPR1	3.33e-04	6	89	2	PF08709
Domain	Kinesin-like	RABGAP1L RABGAP1	3.33e-04	6	89	2	IPR022164
Domain	LAM_G_DOMAIN	EYS CELSR1 USH2A	7.82e-04	38	89	3	PS50025
Domain	NTF2_DOMAIN	NXF5 NXF3	7.91e-04	9	89	2	PS50177
Domain	NTF2	NXF5 NXF3	7.91e-04	9	89	2	IPR002075
Domain	Laminin_G_2	EYS CELSR1 USH2A	9.10e-04	40	89	3	PF02210
Domain	MIR	RYR2 ITPR1	9.86e-04	10	89	2	PS50919
Domain	MIR	RYR2 ITPR1	9.86e-04	10	89	2	PF02815
Domain	MIR	RYR2 ITPR1	9.86e-04	10	89	2	SM00472
Domain	MIR_motif	RYR2 ITPR1	9.86e-04	10	89	2	IPR016093
Domain	Hydrolase_3	ATP8B3 ATP8B4	9.86e-04	10	89	2	PF08282
Domain	LamG	EYS CELSR1 USH2A	1.20e-03	44	89	3	SM00282
Domain	GPCR_Rhodpsn_7TM	OR52B4 OR51B5 OR11L1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 OR5M3	1.31e-03	670	89	10	IPR017452
Domain	7tm_1	OR52B4 OR51B5 OR11L1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 OR5M3	1.41e-03	677	89	10	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR52B4 OR51B5 OR11L1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 OR5M3	1.54e-03	685	89	10	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR52B4 OR51B5 OR11L1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 OR5M3	1.65e-03	691	89	10	PS50262
Domain	GPCR_Rhodpsn	OR52B4 OR51B5 OR11L1 NPY1R HTR2A P2RY2 P2RY4 OR7D2 OR6Y1 OR5M3	1.66e-03	692	89	10	IPR000276
Domain	-	NXF5 NXF3	1.69e-03	13	89	2	3.10.450.50
Domain	P_typ_ATPase_c	ATP8B3 ATP8B4	1.97e-03	14	89	2	IPR032630
Domain	P-type_ATPase_N	ATP8B3 ATP8B4	1.97e-03	14	89	2	IPR032631
Domain	P-type_ATPase_IV	ATP8B3 ATP8B4	1.97e-03	14	89	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B3 ATP8B4	1.97e-03	14	89	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B3 ATP8B4	1.97e-03	14	89	2	PF16209
Domain	NTF2-like_dom	NXF5 NXF3	2.26e-03	15	89	2	IPR032710
Domain	Laminin_G	EYS CELSR1 USH2A	2.67e-03	58	89	3	IPR001791
Domain	MFS_dom	SLC15A2 SLC17A1 SLC16A7 MFSD12	3.86e-03	134	89	4	IPR020846
Domain	ConA-like_dom	EYS CELSR1 HERC1 USH2A RYR2	3.96e-03	219	89	5	IPR013320
Domain	RCC1	IBTK HERC1	4.03e-03	20	89	2	PF00415
Domain	RCC1_1	IBTK HERC1	4.45e-03	21	89	2	PS00625
Domain	RCC1_2	IBTK HERC1	4.45e-03	21	89	2	PS00626
Domain	RCC1_3	IBTK HERC1	4.45e-03	21	89	2	PS50012
Domain	Reg_chr_condens	IBTK HERC1	4.87e-03	22	89	2	IPR000408
Domain	-	IBTK HERC1	4.87e-03	22	89	2	2.130.10.30
Domain	RCC1/BLIP-II	IBTK HERC1	5.32e-03	23	89	2	IPR009091
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP8B3 ABCC3 ATP8B4 CLCN7 SLC15A2 SLC17A1 ABCA12 SLC4A4 SLC12A7 SLC16A7 RYR2 TPCN1	7.62e-05	681	67	12	MM14985
Pubmed	Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.	EVI5 RABGAP1L RABGAP1 EVI5L	6.19e-06	43	96	4	19077034
Pubmed	Distribution of P2Y receptor subtypes on haematopoietic cells.	P2RY2 P2RY4	7.54e-06	2	96	2	9535005
Pubmed	K+ secretion activated by luminal P2Y2 and P2Y4 receptors in mouse colon.	P2RY2 P2RY4	7.54e-06	2	96	2	15718265
Pubmed	Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line.	P2RY2 P2RY4	7.54e-06	2	96	2	19836435
Pubmed	ATP modulates transcription factors through P2Y2 and P2Y4 receptors via PKC/MAPKs and PKC/Src pathways in MCF-7 cells.	P2RY2 P2RY4	7.54e-06	2	96	2	19900397
Pubmed	The Evi5 family in cellular physiology and pathology.	EVI5 EVI5L	7.54e-06	2	96	2	23669355
Pubmed	Patient-specific induced pluripotent stem cell properties implicate Ca2+-homeostasis in clinical arrhythmia associated with combined heterozygous RYR2 and SCN10A variants.	SCN10A RYR2	7.54e-06	2	96	2	37122207
Pubmed	Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6.	RYR2 ITPR1	2.26e-05	3	96	2	12754204
Pubmed	Central role of PD-L1 in cardioprotection resulting from P2Y4 nucleotide receptor loss.	P2RY4 CD274	2.26e-05	3	96	2	36248854
Pubmed	Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.	P2RY2 P2RY4	2.26e-05	3	96	2	19890001
Pubmed	STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.	CD274 STT3A	2.26e-05	3	96	2	29765039
Pubmed	GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.	GLIPR1 IZUMO1	2.26e-05	3	96	2	31672133
Pubmed	Cloning and functional characterization of two murine uridine nucleotide receptors reveal a potential target for correcting ion transport deficiency in cystic fibrosis gallbladder.	P2RY2 P2RY4	2.26e-05	3	96	2	11259526
Pubmed	Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice.	P2RY2 P2RY4	2.26e-05	3	96	2	12644577
Pubmed	Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.	HLA-A CD274	2.26e-05	3	96	2	34873175
Pubmed	Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer.	KDM4C CD274	2.26e-05	3	96	2	32483441
Pubmed	Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.	P2RY2 P2RY4	2.26e-05	3	96	2	12603858
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR2 ITPR1	2.26e-05	3	96	2	9986730
Pubmed	Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells.	P2RY2 P2RY4	2.26e-05	3	96	2	20630102
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R16 TAS2R39 TAS2R19	3.02e-05	22	96	3	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R16 TAS2R39 TAS2R19	3.47e-05	23	96	3	20022913
Pubmed	Receptors for bitter and sweet taste.	TAS2R16 TAS2R39 TAS2R19	4.49e-05	25	96	3	12139982
Pubmed	Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.	P2RY2 P2RY4	4.51e-05	4	96	2	12814360
Pubmed	Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.	P2RY2 P2RY4	4.51e-05	4	96	2	19423692
Pubmed	Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages.	P2RY2 P2RY4	4.51e-05	4	96	2	16980298
Pubmed	Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis.	NXF5 NXF3	4.51e-05	4	96	2	21308854
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR2 ITPR1	4.51e-05	4	96	2	23413940
Pubmed	P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system.	P2RY2 P2RY4	4.51e-05	4	96	2	12151016
Pubmed	Frequency changes in HLA-I alleles: A marker to guide immunotherapy in lung adenocarcinoma patients and its relationship with tumor mutational burden and PD-L1 expression.	HLA-A CD274	4.51e-05	4	96	2	37246469
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR2 ITPR1	4.51e-05	4	96	2	9607712
Pubmed	Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability.	NXF5 NXF3	4.51e-05	4	96	2	23675524
Pubmed	FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body.	ATP8B3 ATP8B4	4.51e-05	4	96	2	12880872
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR2 ITPR1	4.51e-05	4	96	2	19120137
Pubmed	FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.	CD274 STT3A	4.51e-05	4	96	2	37658376
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R16 TAS2R39 TAS2R19	5.06e-05	26	96	3	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R16 TAS2R39 TAS2R19	5.68e-05	27	96	3	12581520
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R16 TAS2R39 TAS2R19	6.35e-05	28	96	3	15744053
Pubmed	Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.	NXF5 NXF3	7.50e-05	5	96	2	17978099
Pubmed	Intracellular calcium-release channels: regulators of cell life and death.	RYR2 ITPR1	7.50e-05	5	96	2	9124414
Pubmed	Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study.	P2RY2 P2RY4	7.50e-05	5	96	2	11690642
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R16 TAS2R39 TAS2R19	7.84e-05	30	96	3	12679530
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 ITPR1	1.12e-04	6	96	2	23463619
Pubmed	International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels.	CATSPER3 TPCN1	1.12e-04	6	96	2	16382101
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 ITPR1	1.12e-04	6	96	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 ITPR1	1.12e-04	6	96	2	25966694
Pubmed	Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages.	P2RY2 P2RY4	1.12e-04	6	96	2	15670583
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR2 ITPR1	1.12e-04	6	96	2	16844763
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R16 TAS2R39 TAS2R19	1.15e-04	34	96	3	15496549
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GLIPR1 DHX36 ABCC3 CELSR1 HLA-A TMEM259 RABGAP1 CERS6 ZDHHC13 STT3A ITPR1 TPCN1	1.18e-04	1201	96	12	35696571
Pubmed	Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.	P2RY2 P2RY4	1.57e-04	7	96	2	25003238
Pubmed	Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.	P2RY2 P2RY4	1.57e-04	7	96	2	21413988
Pubmed	CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.	ATP8B3 ATP8B4	1.57e-04	7	96	2	20961850
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR2 ITPR1	1.57e-04	7	96	2	11860456
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	HLA-A CLCN7 COG1 RABGAP1L HERC1 ELOVL6 SLC4A4 SLC12A7 ZDHHC13 STT3A NUP205	1.68e-04	1061	96	11	33845483
Pubmed	Functional dissection of Rab GTPases involved in primary cilium formation.	EVI5 RABGAP1 EVI5L	2.32e-04	43	96	3	17646400
Pubmed	Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.	HLA-A CD274	2.68e-04	9	96	2	18354207
Pubmed	NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.	NXF5 NXF3	2.68e-04	9	96	2	11566096
Pubmed	Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.	CD274 MFSD12	3.34e-04	10	96	2	11500834
Pubmed	Genome-wide and gene-based association studies of anxiety disorders in European and African American samples.	TTC7B TMEM132D	3.34e-04	10	96	2	25390645
Pubmed	Molecular cloning and functional characterization of mouse Nxf family gene products.	NXF5 NXF3	3.34e-04	10	96	2	15820316
Pubmed	Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.	HTR2A SERPINA6	3.34e-04	10	96	2	20403506
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	EVI5 DHX36 MAP3K15 HERC1 USH2A	4.63e-04	231	96	5	36597993
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R16 TAS2R19	4.89e-04	12	96	2	12379855
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP8B3 ATP8B4	5.77e-04	13	96	2	11015572
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CLCN7 KCNJ16 SCN10A RYR2	6.11e-04	139	96	4	16985003
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH17	6.71e-04	14	96	2	9373155
Pubmed	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.	NXF5 NXF3	6.71e-04	14	96	2	11073998
Pubmed	Large-scale phosphorylation analysis of mouse liver.	HLA-A RABGAP1L	6.71e-04	14	96	2	17242355
Pubmed	The human olfactory receptor gene family.	OR52B4 OR51B5 OR11L1 OR7D2 OR6Y1 OR5M3 OR52Z1P	7.67e-04	541	96	7	14983052
Pubmed	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.	OR51B5 OR52Z1P	7.73e-04	15	96	2	11121057
Pubmed	1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.	IGHV3-13 IGHV3-64D	7.73e-04	15	96	2	12657787
Pubmed	Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.	OR51B5 OR52Z1P	7.73e-04	15	96	2	10220430
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	HLA-A CLCN7 PARP16 MFSD12 STT3A TPCN1	7.80e-04	392	96	6	33144569
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	FRMD4A IBTK COG1 ARHGAP20	8.74e-04	153	96	4	10718198
Pubmed	Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.	SLC15A2 SLC17A1	8.82e-04	16	96	2	19679677
Pubmed	The immunoregulatory effects of HIV-1 Nef on dendritic cells and the pathogenesis of AIDS.	MRC1 HLA-A	1.25e-03	19	96	2	17077296
Pubmed	Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.	KDM4C TPCN1	1.25e-03	19	96	2	23149075
Pubmed	A novel family of mammalian taste receptors.	TAS2R16 TAS2R19	1.53e-03	21	96	2	10761934
Pubmed	Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways.	EVI5 RABGAP1	1.53e-03	21	96	2	17562788
Pubmed	Dissociation of heterotrimeric g proteins in cells.	NPY1R HTR2A P2RY2 P2RY4	1.56e-03	179	96	4	18577758
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV3-13 IGHV3-64D	1.68e-03	22	96	2	2499654
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC3 ABCA12	1.68e-03	22	96	2	8894702
Pubmed	Rare independent mutations in renal salt handling genes contribute to blood pressure variation.	KCNJ16 SLC12A7	1.68e-03	22	96	2	18391953
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	EYS TMEM132D USH2A RYR2	2.29e-03	199	96	4	23382691
Pubmed	Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.	RABGAP1L RABGAP1	2.53e-03	27	96	2	22354992
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	CERS6 ELOVL6	2.53e-03	27	96	2	25269881
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR52B4 OR11L1 OR6Y1 OR5M3 OR52Z1P	2.56e-03	340	96	5	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR52B4 OR11L1 OR6Y1 OR5M3 OR52Z1P	2.56e-03	340	96	5	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR52B4 OR11L1 OR6Y1 OR5M3 OR52Z1P	2.66e-03	343	96	5	32295537
Pubmed	Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.	HTR2A GRIN2A	2.72e-03	28	96	2	19352218
Pubmed	Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.	RYR2 ITPR1	2.72e-03	28	96	2	25332179
Pubmed	A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.	NXF5 NXF3	2.72e-03	28	96	2	23677977
Interaction	VIPR2 interactions	CDS1 COG1 RABGAP1L RABGAP1 CERS6 ZDHHC13 EVI5L NUP205	2.12e-06	194	88	8	int:VIPR2
GeneFamily	Taste 2 receptors	TAS2R16 TAS2R39 TAS2R19	4.60e-04	39	70	3	1162
GeneFamily	Purinergic receptors P2Y	P2RY2 P2RY4	6.52e-04	10	70	2	213
GeneFamily	ATPase phospholipid transporting	ATP8B3 ATP8B4	1.50e-03	15	70	2	1210
GeneFamily	Dyneins, axonemal	DNAH3 DNAH17	1.94e-03	17	70	2	536
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE KCTD19 ABCA12 MROH2A USH2A RYR2	1.23e-06	160	95	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE KCTD19 ABCA12 MROH2A USH2A RYR2	1.23e-06	160	95	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	TRHDE FRMD4A ELOVL6 SLC4A4 ARHGAP20 SLC16A7	2.44e-06	180	95	6	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	TRHDE GPLD1 FRMD4A ELOVL6 SLC4A4 ARHGAP20	2.68e-06	183	95	6	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	TRHDE GPLD1 FRMD4A SLC4A4 ARHGAP20 SLC16A7	2.68e-06	183	95	6	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ABCA12 MROH2A SLC4A4 USH2A RYR2	2.77e-06	184	95	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ABCA12 MROH2A SLC4A4 USH2A RYR2	2.77e-06	184	95	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ABCA12 MROH2A SLC4A4 USH2A RYR2	2.77e-06	184	95	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A NPY1R KCNJ16 MED12L SLC16A7 ITPR1	3.87e-06	195	95	6	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYS SLC17A1 TMEM132D ABCA12 GRIN2A	1.21e-05	139	95	5	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	EYS TMEM132D GRIN2A USH2A RYR2	1.54e-05	146	95	5	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATP8B3 DNAH3 ABCA12 CHRNB4	1.72e-05	72	95	4	e3f4d1df43cc41b0424f27485a00ddca9e905f95
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 EYS TMEM132D USH2A RYR2	2.32e-05	159	95	5	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 EYS TMEM132D USH2A RYR2	2.61e-05	163	95	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRHDE EYS HTR2A ABCA12 SCN10A	3.47e-05	173	95	5	2e35bf2b5534a289d93a09faae660f665c131062
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRMD4A KCTD19 KCNJ16 SLC16A7 ITPR1	3.47e-05	173	95	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCC3 EYS CELSR1 ARHGAP40 SLC4A4	3.77e-05	176	95	5	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	EVI5 MRC1 FRMD4A TTC7B P2RY2	3.87e-05	177	95	5	52c2ba74a8605260a2623e7d151286e504ac4d19
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH3 TMEM132D GRIN2A USH2A RYR2	4.31e-05	181	95	5	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A1 UGT2A3 KCNJ16 PWWP3B SLC4A4	4.31e-05	181	95	5	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE ABCC3 SLC17A1 UGT2A3 KCNJ16	4.54e-05	183	95	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPY1R KCNJ16 MED12L SLC16A7 ITPR1	5.29e-05	189	95	5	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE CDS1 CELSR1 TMEM132D UGT2A3	5.29e-05	189	95	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 CELSR1 SLC15A2 KCNJ16 SLC4A4	5.70e-05	192	95	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE CELSR1 SLC17A1 KCNJ16 SLC4A4	5.84e-05	193	95	5	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	Caecum-T_cell-Tfh\|T_cell / Region, Cell class and subclass	GPLD1 CDS1 CELSR1 TTC7B CATSPER3	6.29e-05	196	95	5	fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 CDS1 UGT2A3 PWWP3B SLC4A4	6.29e-05	196	95	5	153326be031a58b720da4dab57edd8936d513f8e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 CDS1 UGT2A3 PWWP3B SLC4A4	6.29e-05	196	95	5	b7748618aaf3ace40940be1b6ca2148e941541a2
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMD4A CERS6 GRIN2A RYR2 ITPR1	6.60e-05	198	95	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMD4A CERS6 GRIN2A RYR2 ITPR1	6.60e-05	198	95	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 ABCC3 FRMD4A ATP8B4 TTC7B	6.60e-05	198	95	5	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CELSR1 ARHGAP40 SLC15A2 PWWP3B SLC4A4	6.60e-05	198	95	5	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMD4A CERS6 GRIN2A HERC1 RYR2	6.60e-05	198	95	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	FRMD4A CERS6 GRIN2A HERC1 RYR2	6.92e-05	200	95	5	48d801219bc771d6c7e151dc88ca4c179988de85
Drug	Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; MCF7; HT_HG-U133A	EVI5 GPLD1 SLC15A2 ABCA12 PARP16 RYR2 ITPR1	1.44e-05	195	92	7	5618_DN
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	EVI5 FRMD4A NPY1R TMEM259 PARP16 RABGAP1 SLC16A7	1.54e-05	197	92	7	2812_DN
Drug	AC1L1IZE	DNAH3 P2RY2 P2RY4 DNAH17 SERPINA6 RYR2	1.54e-05	131	92	6	CID000004799
Drug	fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	EVI5 DNAH3 PARP16 CAMTA2 ELOVL6 SLC4A4 ITPR1	1.59e-05	198	92	7	1237_DN
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A	EVI5 ABCC3 DNAH3 CLCN7 DNAH17 RYR2 TPCN1	1.59e-05	198	92	7	3990_DN
Drug	N-butyrylhomoserine lactone	P2RY2 P2RY4	1.62e-05	2	92	2	ctd:C092312
Drug	Pizotifen malate [5189-11-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	GLIPR1 GPLD1 CLCN7 TMEM259 DNAH17 SLC4A4 TPCN1	1.64e-05	199	92	7	6513_DN
Drug	sodium	ATP8B3 ABCC3 ACTL8 SLC15A2 P2RY2 SACS SLC17A1 KCNJ16 SCN10A CATSPER3 SLC4A4 SERPINA6 RYR2 TPCN1	2.50e-05	944	92	14	CID000000923
Disease	Alcohol dependence	TAS2R16 HTR2A	9.15e-05	5	90	2	cv:C0001973
Disease	ALCOHOL DEPENDENCE	TAS2R16 HTR2A	9.15e-05	5	90	2	103780
Disease	X-16935 measurement	ABCC3 ATP8B4	1.91e-04	7	90	2	EFO_0800763
Disease	programmed cell death 1 ligand 2 measurement	DHX36 CD274	2.55e-04	8	90	2	EFO_0008268
Disease	episodic memory	TRHDE HTR2A GRIN2A	5.44e-04	52	90	3	EFO_0004333
Disease	cesarean section, intelligence	TMEM132D GRIN2A	5.95e-04	12	90	2	EFO_0004337, EFO_0009636
Disease	Alzheimer disease	MRC1 FRMD4A ATP8B4 MED12L ARHGAP20 C17orf107 TPCN1	7.17e-04	485	90	7	MONDO_0004975
Disease	alcohol use disorder (is_implicated_in)	TAS2R16 HTR2A	1.07e-03	16	90	2	DOID:1574 (is_implicated_in)
Disease	4-ethylphenylsulfate measurement	ATP8B4 SLC17A1	1.36e-03	18	90	2	EFO_0021148
Disease	alpha-tocopherol measurement	KDM4C USH2A	1.69e-03	20	90	2	EFO_0007898
Disease	aspartate aminotransferase measurement	MRC1 HLA-A P2RY2 TMEM132D RABGAP1 SLC4A4 SERPINA6 MFSD12 ITPR1	1.76e-03	904	90	9	EFO_0004736
Disease	lung adenocarcinoma	ATP8B4 HLA-A SLC12A7 CHRNB4	2.01e-03	174	90	4	EFO_0000571
Disease	response to selective serotonin reuptake inhibitor	OR52B4 OR51B5 OR11L1	2.04e-03	82	90	3	EFO_0005658
Disease	hormone measurement	ACTL8 TMEM132D RYR2	2.19e-03	84	90	3	EFO_0004730
Disease	pulmonary embolism	TMEM132D DNAH17	2.64e-03	25	90	2	EFO_0003827
Disease	systemic mastocytosis	OR51B5 EYS	2.64e-03	25	90	2	MONDO_0016586
Disease	urate measurement, bone density	GLIPR1 EYS HTR2A RABGAP1L CATSPER3 USH2A ITPR1	2.88e-03	619	90	7	EFO_0003923, EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
WVTDHFSQTPLMSTY	TRHDE	316	Q9UKU6
FRSWTYDHTEIDMVL	CHRNB4	171	P30926
FRSQSFHTSMYASSW	EVI5L	261	Q96CN4
FHTSMYASSWFLTLF	EVI5L	266	Q96CN4
FYMFAWTHVTLLITV	CDS1	211	Q92903
TSNAFFMALWTSYDI	CATSPER3	61	Q86XQ3
ASVVAHLSTYQSEWM	ACTL8	341	Q9H568
YHPSTEALVSAMWDF	ABCA12	1796	Q86UK0
TFSWMYLLAGLFHET	ABCA12	2081	Q86UK0
WIYLDVLFSTASIMH	HTR2A	151	P28223
AYAFFRHIWQVSLMT	CFAP46	1326	Q8IYW2
TMSWLASYLENVDHF	CAMTA2	981	O94983
LGFYAIMTTTTQSFW	ATP8B3	1151	O60423
WGSIAIYFSILFTMH	ATP8B4	1026	Q8TF62
IYMSTFAWTLVESLH	CELSR1	2541	Q9NYQ6
VFIFMTYWHLLNAFT	CD274	6	Q9NZQ7
TFLSFSLSWEEMFYA	KCTD19	806	Q17RG1
RTAAYLHTTTTFTWM	ABCC3	526	O15438
SPVSWEHFFHSLMLY	NUP205	551	Q92621
YTMILHSVFQISSWA	OR52Z1P	201	P0C646
ISLEAHMYASQWFLT	RABGAP1	716	Q9Y3P9
HMYASQWFLTLFTAK	RABGAP1	721	Q9Y3P9
QHDLSSFLVDMWYQT	NXF3	431	Q9H4D5
ATIAWMVSFVSNYSH	GLIPR1	6	P48060
SSNSMETLYHKIFWA	MED12L	476	Q86YW9
HFYETFWMNSAILAS	EYS	1581	Q5T1H1
YTSNHMWKLFENFLV	ITPR1	1451	Q14643
HSWIFTNMTVRFFSF	HACD4	31	Q5VWC8
FTFSSYAMHWVRQAP	IGHV3-30-3	46	P0DP02
LEYFHSMLSSSWIEA	IBTK	791	Q9P2D0
LLSEPSSVSFYNWMS	KIAA1109	2341	Q2LD37
HFSDLMYSSWRLLNL	HERC1	4406	Q15751
FTFSSYDMHWVRQAT	IGHV3-13	46	P01766
FTLNFVLSIYHGNMW	CLCN7	336	P51798
TQHDFTSILVDMWYQ	NXF5	331	Q9H1B4
AHHWISVFFLFMYIS	OR51B5	21	Q9H339
HMWISIPFFISYVTA	OR52B4	26	Q8NGK2
SQSFHTSMYASSWFL	EVI5	311	O60447
TFAWHTEDMDLYSIN	KDM4C	186	Q9H3R0
FHTTYSEIAWISSIM	SLC16A7	51	O60669
FTFSSYAMHWVRQAP	IGHV3-64D	46	A0A0J9YX35
MFLQHLSFLEVWYTS	OR11L1	61	Q8NGX0
PMYFFLSHLSFVDVW	OR5M3	56	Q8NGP4
RLKTWNASTTYMFHL	P2RY2	61	P41231
SDLNLEAHMYASQWF	RABGAP1L	686	Q5R372
EAHMYASQWFLTLFT	RABGAP1L	691	Q5R372
FSSHWFTVMISLYLL	PARP16	286	Q8N5Y8
PWDATATYMFHLALS	P2RY4	66	P51582
FTFVYTLMDHWVFGE	NPY1R	96	P25929
MSLASLHFLWQTLDY	PATL2	91	C9JE40
SIWAMAISQHQFYLD	FRMD4A	306	Q9P2Q2
HSHFQNIFWSSLMYL	ELOVL6	226	Q9H5J4
LWFSHSMFMGFYLLS	BLCAP	21	P62952
HFEYNMSLFLWSESP	COG1	466	Q8WTW3
WEVKASISFFMSYVH	DNAH17	2981	Q9UFH2
SLTWFINLYMHSLTH	DNAH3	3321	Q8TD57
CWEYFLSSNTLQMLH	DHX36	781	Q9H2U1
SSLDTLMWIYHFHSS	C17orf107	6	Q6ZR85
LMWIYHFHSSTEVAL	C17orf107	11	Q6ZR85
LSFYWSLMFSQFTDI	CERS6	186	Q6ZMG9
QTWAGSHSMRYFFTS	HLA-A	21	P04439
LVTSWLFIQHSMIYF	TMEM259	431	Q4ZIN3
HVLMSDWSVSFTSLY	DONSON	256	Q9NYP3
LFWMLHLQKETFATY	IZUMO1	111	Q8IYV9
FKFYHWTLSFLGMSL	SLC12A7	611	Q9Y666
FLYFLHWNEDTSTSI	SLC15A2	71	Q16348
NAFYSHEEVTQLMLW	SACS	1001	Q9NZJ4
SYWSIFMTLLHFVAS	RYR2	4286	Q92736
ASMWFTYLLLYLHSV	MFSD12	36	Q6NUT3
MIFDHFTWSSLFLAR	SERPINA6	386	P08185
SLHLYLMWIYVHSTA	MROH2A	971	A6NES4
LTYHMKDSTFSAWTG	MRC1	996	P22897
YWDVGQFFSVSMLAH	MAP3K15	446	Q6ZN16
FSSDLYDHWVSVMDQ	ARHGAP20	446	Q9P2F6
FYHTWTHLFNLLAML	RTTN	1736	Q86VV8
WEAFVYAFILMHSTS	TAS2R16	261	Q9NYV7
TNHFSMWLAASLSIF	TAS2R19	91	P59542
LLWLSVFISFSHSMF	TAS2R39	161	P59534
YVLYMSNHTHDFTIW	USH2A	2176	O75445
WMNHYLVSFVIVTTA	RNF133	186	Q8WVZ7
FTYQHLSSPLEMTVW	TMEM132D	506	Q14C87
HHYVSTFLSGVMLTW	TMEM120A	196	Q9BXJ8
FSASNPVWDYSHLMS	PWWP3B	321	Q5H9M0
SFTFFWSHNIMTLYT	SLC17A1	271	Q14916
FFLITYTFHSTWVTS	STT3A	466	P46977
HTPMYFFLSNLSWVD	OR7D2	56	Q96RA2
FFLSHLSFLEMWYVT	OR6Y1	66	Q8NGX8
VSYLTAASFLQMWHV	ZBTB43	101	O43298
LYILMLATFHFSWST	ZDHHC13	521	Q8IUH4
MVHYQDLLWTVASFL	ARHGAP40	461	Q5TG30
RMTAHLFTAWFTEYF	TIGD1	266	Q96MW7
HSWFESFIIFMILLS	SCN10A	1151	Q9Y5Y9
IRYTAPWHMVFFSES	TMEM53	66	Q6P2H8
RHMFVIFSLSYILSW	KCNJ16	71	Q9NPI9
LDDMAFWSTNIYHLT	GPLD1	251	P80108
FWSTNIYHLTSFMLE	GPLD1	256	P80108
VTSQTSHWSRLYFMT	TPCN1	656	Q9ULQ1
SHWSRLYFMTFYIVT	TPCN1	661	Q9ULQ1
YALDSIMQTWFTLFT	ZSWIM6	931	Q9HCJ5
EFHLWYQFALSLMAA	TTC7B	396	Q86TV6
NSMLSVLFHFWIQDY	UGT2A3	211	Q6UWM9
TDMYHNTTFDWAFLS	SLC4A4	656	Q9Y6R1
VMYSHFAQDLWSEQS	ZNF506	76	Q5JVG8
IMQDYDWHVFSLVTT	GRIN2A	161	Q12879