Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT81 KRT83 KRT86

5.64e-0443753GO:0030280
GeneOntologyMolecularFunctionmiRNA binding

AGO2 AGO1 AGO4

7.80e-0448753GO:0035198
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BRCA2 KAT8 CREBBP

9.31e-0451753GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BRCA2 KAT8 CREBBP

1.16e-0355753GO:0061733
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

BRCA2 CREBBP

1.42e-0315752GO:0010484
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BRCA2 KAT8 CREBBP

1.49e-0360753GO:0034212
GeneOntologyMolecularFunctionregulatory RNA binding

AGO2 AGO1 AGO4

1.64e-0362753GO:0061980
GeneOntologyMolecularFunctionHsp70 protein binding

AGO2 DNAJC10 CYP2E1

1.72e-0363753GO:0030544
GeneOntologyMolecularFunctionendonuclease activity

AGO2 AGO1 AGO4 TSN

1.72e-03136754GO:0004519
GeneOntologyMolecularFunctionprotein kinase activity

TNIK AKT3 CSF1R GUCY2C DBF4 ELP1 MAP2K7 DYRK2

1.82e-03600758GO:0004672
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

AGO2 AGO1 CREBBP

1.97e-0366753GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

AGO2 AGO1 CREBBP

1.97e-0366753GO:0001098
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH1

2.05e-0318752GO:0008569
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE6A PDE6B

3.06e-0322752GO:0004115
GeneOntologyMolecularFunctiondouble-stranded RNA binding

AGO2 AGO1 AGO4

3.16e-0378753GO:0003725
GeneOntologyMolecularFunctionN-acetyltransferase activity

BRCA2 KAT8 CREBBP

3.16e-0378753GO:0008080
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PDE6A AGO2 AGO1 AGO4 NANP PDE6B PON1 TSN MGLL

3.18e-03807759GO:0016788
GeneOntologyMolecularFunctionRNA endonuclease activity

AGO2 AGO1 AGO4

3.28e-0379753GO:0004521
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

BRCA2 KAT8

3.35e-0323752GO:0010485
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE6A PDE6B

3.64e-0324752GO:0047555
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

RBL1 KAT8 PRDM15

3.77e-0383753GO:1990841
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE6A PDE6B

3.95e-0325752GO:0004114
GeneOntologyBiologicalProcesssiRNA-mediated post-transcriptional gene silencing

AGO2 AGO1 AGO4

1.84e-074753GO:0140766
GeneOntologyBiologicalProcesssiRNA-mediated gene silencing by mRNA destabilization

AGO2 AGO1 AGO4

1.84e-074753GO:0090625
GeneOntologyBiologicalProcessRNA secondary structure unwinding

AGO2 AGO1 AGO4

3.82e-069753GO:0010501
GeneOntologyBiologicalProcessRISC complex assembly

AGO2 AGO1 AGO4

5.44e-0610753GO:0070922
GeneOntologyBiologicalProcesspre-miRNA processing

AGO2 AGO1 AGO4

3.03e-0517753GO:0031054
GeneOntologyBiologicalProcessregulatory ncRNA processing

AGO2 AGO1 AGO4 TSN

1.53e-0474754GO:0070918
GeneOntologyBiologicalProcessmicrotubule bundle formation

DNAH17 CAPN6 CC2D2A HYDIN DNAH1

1.86e-04145755GO:0001578
GeneOntologyBiologicalProcesscilium assembly

SYNE1 DNAH17 CC2D2A CEP126 CFAP70 HYDIN EHD4 DNAH1

2.07e-04444758GO:0060271
GeneOntologyCellularComponentRISC-loading complex

AGO2 AGO1 AGO4

5.44e-0610763GO:0070578
GeneOntologyCellularComponentendoribonuclease complex

AGO2 AGO1 AGO4 TSN

9.73e-0637764GO:1902555
GeneOntologyCellularComponentendonuclease complex

AGO2 AGO1 AGO4 TSN

1.79e-0543764GO:1905348
GeneOntologyCellularComponentdynein complex

DNAH17 CFAP70 DYNC1LI2 DNAH1

4.44e-0554764GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH17 CFAP70 DNAH1

1.00e-0425763GO:0005858
GeneOntologyCellularComponentsupramolecular fiber

ANK3 KRT81 KRT83 SYNE1 KRT86 DNAH17 CAPN6 CMYA5 NEB GGPS1 DYNC1LI2 MX2 DNAH1

3.02e-0411797613GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

ANK3 KRT81 KRT83 SYNE1 KRT86 DNAH17 CAPN6 CMYA5 NEB GGPS1 DYNC1LI2 MX2 DNAH1

3.22e-0411877613GO:0099081
GeneOntologyCellularComponentP-body

AGO2 AGO1 AGO4 SYNE1

5.24e-04102764GO:0000932
GeneOntologyCellularComponentintracellular protein-containing complex

AGO2 AGO1 AGO4 BRCA2 KAT8 MARCHF6 ELP1 TSN FBXO39 CREBBP DYRK2

7.45e-049727611GO:0140535
GeneOntologyCellularComponentouter dynein arm

DNAH17 CFAP70

8.41e-0412762GO:0036157
HumanPhenoPerifollicular hyperkeratosis

KRT81 KRT83 KRT86

1.29e-064363HP:0007468
HumanPhenoAbnormal perifollicular morphology

KRT81 KRT83 KRT86

6.39e-066363HP:0031285
DomainArgonaute_N

AGO2 AGO1 AGO4

2.38e-074743IPR032474
DomainArgonaute_Mid_dom

AGO2 AGO1 AGO4

2.38e-074743IPR032473
DomainArgoL2

AGO2 AGO1 AGO4

2.38e-074743IPR032472
DomainArgoN

AGO2 AGO1 AGO4

2.38e-074743PF16486
DomainArgoMid

AGO2 AGO1 AGO4

2.38e-074743PF16487
DomainArgoL2

AGO2 AGO1 AGO4

2.38e-074743PF16488
DomainDUF1785

AGO2 AGO1 AGO4

5.94e-075743SM01163
DomainArgoL1

AGO2 AGO1 AGO4

1.18e-066743PF08699
DomainArgoL1

AGO2 AGO1 AGO4

1.18e-066743IPR014811
DomainPIWI

AGO2 AGO1 AGO4

3.30e-068743PS50822
DomainPiwi

AGO2 AGO1 AGO4

3.30e-068743SM00950
DomainPiwi

AGO2 AGO1 AGO4

3.30e-068743IPR003165
DomainPiwi

AGO2 AGO1 AGO4

3.30e-068743PF02171
DomainPAZ

AGO2 AGO1 AGO4

4.93e-069743PS50821
DomainPAZ

AGO2 AGO1 AGO4

4.93e-069743SM00949
DomainPAZ_dom

AGO2 AGO1 AGO4

4.93e-069743IPR003100
DomainPAZ

AGO2 AGO1 AGO4

4.93e-069743PF02170
DomainBROMODOMAIN_1

BRD7 ASH1L ATAD2 CREBBP

1.36e-0537744PS00633
DomainBromodomain

BRD7 ASH1L ATAD2 CREBBP

1.51e-0538744PF00439
DomainBROMODOMAIN_2

BRD7 ASH1L ATAD2 CREBBP

2.06e-0541744PS50014
DomainBROMO

BRD7 ASH1L ATAD2 CREBBP

2.27e-0542744SM00297
DomainBromodomain

BRD7 ASH1L ATAD2 CREBBP

2.27e-0542744IPR001487
Domain-

BRD7 ASH1L ATAD2 CREBBP

2.27e-05427441.20.920.10
DomainKeratin_2_head

KRT81 KRT83 KRT86

1.14e-0424743IPR032444
DomainKeratin_2_head

KRT81 KRT83 KRT86

1.14e-0424743PF16208
DomainKeratin_II

KRT81 KRT83 KRT86

1.45e-0426743IPR003054
DomainGAF

PDE6A PDE6B

3.21e-047742PF01590
DomainGAF

PDE6A PDE6B

4.27e-048742IPR003018
DomainGAF

PDE6A PDE6B

4.27e-048742SM00065
DomainPH_dom-spectrin-type

PSD2 PSD3

5.48e-049742IPR001605
DomainGAF_dom-like

PDE6A PDE6B

5.48e-049742IPR029016
Domain-

PDE6A PDE6B

5.48e-0497423.30.450.40
Domain-

AGO2 AGO1 AGO4

8.54e-04477433.30.420.10
DomainG_DYNAMIN_dom

MX2 EHD4

1.37e-0314742IPR030381
DomainCNH

TNIK VPS39

1.37e-0314742SM00036
DomainG_DYNAMIN_2

MX2 EHD4

1.37e-0314742PS51718
DomainDynamin_GTPase

MX2 EHD4

1.57e-0315742IPR001401
DomainDynamin_N

MX2 EHD4

1.57e-0315742PF00350
Domain-

PSD2 PSD3

1.57e-03157421.10.1000.11
DomainCNH

TNIK VPS39

1.57e-0315742PF00780
DomainDynamin_SF

MX2 EHD4

1.57e-0315742IPR022812
DomainSec7

PSD2 PSD3

1.57e-0315742PF01369
DomainCNH

TNIK VPS39

1.57e-0315742PS50219
DomainCNH_dom

TNIK VPS39

1.57e-0315742IPR001180
DomainSec7_alpha_orthog

PSD2 PSD3

1.57e-0315742IPR023394
DomainSec7

PSD2 PSD3

1.79e-0316742SM00222
DomainSEC7

PSD2 PSD3

1.79e-0316742PS50190
DomainSec7_dom

PSD2 PSD3

1.79e-0316742IPR000904
DomainIntermediate_filament_CS

KRT81 KRT83 KRT86

2.00e-0363743IPR018039
DomainPH

AKT3 PSD2 PSD3 AGAP7P SYNGAP1

2.15e-03229745PF00169
DomainPDEase

PDE6A PDE6B

2.54e-0319742IPR023088
DomainRNaseH-like_dom

AGO2 AGO1 AGO4

2.59e-0369743IPR012337
DomainRCC1

RCBTB2 HERC3

2.81e-0320742PF00415
DomainFilament

KRT81 KRT83 KRT86

2.81e-0371743SM01391
DomainIF

KRT81 KRT83 KRT86

2.93e-0372743PS00226
DomainFilament

KRT81 KRT83 KRT86

3.04e-0373743PF00038
DomainPDEase_I

PDE6A PDE6B

3.10e-0321742PF00233
DomainRCC1_1

RCBTB2 HERC3

3.10e-0321742PS00625
DomainRCC1_2

RCBTB2 HERC3

3.10e-0321742PS00626
DomainRCC1_3

RCBTB2 HERC3

3.10e-0321742PS50012
DomainPDEASE_I

PDE6A PDE6B

3.10e-0321742PS00126
DomainPDEase_CS

PDE6A PDE6B

3.10e-0321742IPR023174
DomainReg_chr_condens

RCBTB2 HERC3

3.40e-0322742IPR000408
Domain-

RCBTB2 HERC3

3.40e-03227422.130.10.30
Domain-

PDE6A PDE6B

3.40e-03227421.10.1300.10
DomainIF

KRT81 KRT83 KRT86

3.41e-0376743IPR001664
DomainPDEase_catalytic_dom

PDE6A PDE6B

3.71e-0323742IPR002073
DomainRCC1/BLIP-II

RCBTB2 HERC3

3.71e-0323742IPR009091
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO2 AGO1 AGO4 TSN

2.19e-088614MM15082
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO2 AGO1 AGO4 TSN

3.93e-089614M27340
PathwayBIOCARTA_DICER_PATHWAY

AGO2 AGO1 AGO4

7.66e-075613M22079
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO2 AGO1 AGO4

1.53e-066613MM14818
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO2 AGO1 AGO4

1.53e-066613MM15083
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO2 AGO1 AGO4

2.67e-067613M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

AGO2 AGO1 AGO4

6.36e-069613M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

AGO2 AGO1 AGO4

6.36e-069613M46436
PathwayREACTOME_CA2_PATHWAY

PDE6A AGO2 AGO1 AGO4 PDE6B

6.87e-0662615M27321
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

AGO2 AGO1 AGO4

9.05e-0610613M48013
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

AGO2 AGO1 AGO4 CREBBP

1.34e-0534614M46422
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

AGO2 AGO1 AGO4

2.14e-0513613M46434
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

AGO2 AGO1 AGO4

5.02e-0517613M27788
PathwayREACTOME_GENE_SILENCING_BY_RNA

AGO2 AGO1 AGO4 TSN

5.81e-0549614MM14837
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

AGO2 AGO1 AGO4

7.11e-0519613M48238
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

AKT3 AGO2 AGO1 AGO4 RBL1 BRD7 CREBBP DYRK2

1.51e-04360618M27267
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO2 AGO1 AGO4

1.66e-0425613M712
PathwayREACTOME_TGFBR3_EXPRESSION

AGO2 AGO1 AGO4

2.34e-0428613M48253
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

AKT3 AGO2 AGO1 AGO4 CREBBP

3.10e-04137615M48232
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

AGO2 AGO1 AGO4

3.50e-0432613M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

AGO2 AGO1 AGO4

3.50e-0432613M27900
PathwayREACTOME_ESR_MEDIATED_SIGNALING

AKT3 AGO2 AGO1 AGO4 GREB1 CREBBP

3.66e-04220616M27794
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

PDE6A AGO2 AGO1 AGO4 PDE6B

4.15e-04146615M27288
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

AGO2 AGO1 AGO4 GREB1 CREBBP

4.56e-04149615M27888
PathwayREACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER

AGO2 AGO1 AGO4

4.57e-0435613M42525
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

AKT3 AGO2 AGO1 AGO4

4.73e-0484614M27495
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

AGO2 AGO1 AGO4

5.39e-0437613M29790
PathwayREACTOME_SIGNALING_BY_ALK_IN_CANCER

AGO2 AGO1 AGO4 RNF213

6.95e-0493614M42521
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

AGO1 AGO4 CSF1R

7.31e-0441613M29748
PathwayBIOCARTA_RHODOPSIN_PATHWAY

PDE6A PDE6B

9.88e-0411612M22044
PathwayREACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE

PDE6A PDE6B

9.88e-0411612M27180
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

AGO2 AGO1 AGO4

1.09e-0347613M29777
PathwayREACTOME_SIGNALING_BY_TGFBR3

AGO2 AGO1 AGO4

1.23e-0349613M48250
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

AKT3 AGO2 AGO1 AGO4 GREB1 CREBBP

1.72e-03296616M27869
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

AGO2 AGO1 AGO4 CREBBP

1.74e-03119614M607
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT83 KRT86

1.00e-08376325557232
Pubmed

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.

AGO2 AGO1 AGO4

1.00e-08376319946268
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT83 KRT86

1.00e-0837631372089
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT83 KRT86

1.00e-0837631712823
Pubmed

Molecular dissection of human Argonaute proteins by DNA shuffling.

AGO2 AGO1 AGO4

4.00e-08476323748378
Pubmed

Slicing-independent RISC activation requires the argonaute PAZ domain.

AGO2 AGO1 AGO4

4.00e-08476322795694
Pubmed

Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.

AGO2 AGO1 AGO4

4.00e-08476318771919
Pubmed

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.

AGO2 AGO1 AGO4

4.00e-08476315260970
Pubmed

Keratins of the human hair follicle.

KRT81 KRT83 KRT86

4.00e-08476315797458
Pubmed

ATP-dependent human RISC assembly pathways.

AGO2 AGO1 AGO4

4.00e-08476319966796
Pubmed

Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.

AGO2 AGO1 AGO4

1.00e-07576319393748
Pubmed

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.

AGO2 AGO1 AGO4

1.00e-07576312414724
Pubmed

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.

AGO2 AGO1 AGO4

1.00e-07576319324964
Pubmed

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.

AGO2 AGO1 AGO4

1.00e-07576312526743
Pubmed

Differential expression of components of the microRNA machinery during mouse organogenesis.

AGO2 AGO1 AGO4

1.00e-07576316036130
Pubmed

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.

AGO2 AGO1 AGO4

3.49e-07776334907157
Pubmed

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

AGO2 AGO1 AGO4

3.49e-07776319536157
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

AGO2 AGO1 AGO4

3.49e-07776319383768
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

AGO2 AGO1 AGO4

3.49e-07776319470757
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

AGO2 AGO1 AGO4

5.57e-07876319345100
Pubmed

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.

AGO2 AGO1 AGO4

5.57e-07876329021386
Pubmed

Identification of eight members of the Argonaute family in the human genome.

AGO2 AGO1 AGO4

8.34e-07976312906857
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT81 KRT83 KRT86

2.17e-061276310692104
Pubmed

Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.

AKT3 AGO2

4.71e-06276223603119
Pubmed

Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.

AGO2 AGO1

4.71e-06276226242502
Pubmed

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.

AGO1 AGO4

4.71e-06276233233493
Pubmed

A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.

KRT83 KRT86

4.71e-06276215744029
Pubmed

Complete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase alpha- and beta-subunits, and identification of beta'-, a putative beta-subunit isozyme produced by alternative splicing of the beta-subunit gene.

PDE6A PDE6B

4.71e-0627621847109
Pubmed

Structural disease progression in PDE6-associated autosomal recessive retinitis pigmentosa.

PDE6A PDE6B

4.71e-06276230153077
Pubmed

Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.

AGO2 AGO1

4.71e-06276216936728
Pubmed

Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.

AGO2 AGO1

4.71e-06276210534406
Pubmed

Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.

AGO2 AGO1

4.71e-06276227518285
Pubmed

Phosphodiesterase inhibitors block the acceleration of skin permeability barrier repair by red light.

PDE6A PDE6B

4.71e-06276221410772
Pubmed

Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population.

AGO2 AGO1

4.71e-06276236142498
Pubmed

A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.

KRT81 KRT86

4.71e-0627629665406
Pubmed

Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.

AGO2 AGO1

4.71e-06276229256262
Pubmed

The cGMP phosphodiesterase-transducin complex of retinal rods. Membrane binding and subunits interactions.

PDE6A PDE6B

4.71e-0627621326553
Pubmed

A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.

KRT81 KRT86

4.71e-0627629402962
Pubmed

Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families.

PDE6A PDE6B

4.71e-06276235033039
Pubmed

Argonaute proteins couple chromatin silencing to alternative splicing.

AGO2 AGO1

4.71e-06276222961379
Pubmed

Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse.

PDE6A PDE6B

4.71e-06276223864662
Pubmed

Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.

PDE6A PDE6B

4.71e-06276220940301
Pubmed

Association study of AGO1 and AGO2 genes polymorphisms with recurrent pregnancy loss.

AGO2 AGO1

4.71e-06276231666609
Pubmed

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.

AGO2 AGO1

4.71e-06276223019594
Pubmed

Beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase. Comparison with the phosphodiesterase family.

PDE6A PDE6B

4.71e-0627622165490
Pubmed

Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases.

PDE6A PDE6B

4.71e-06276234170501
Pubmed

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma.

AGO2 AGO1

4.71e-06276222858679
Pubmed

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.

AGO2 AGO1

4.71e-06276212230974
Pubmed

Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.

AGO1 AGO4

4.71e-06276226995025
Pubmed

mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer.

AGO2 AGO1

4.71e-06276219723326
Pubmed

Evaluation of Argonaute protein as a predictive marker for human clear cell renal cell carcinoma.

AGO2 AGO1

4.71e-06276223696926
Pubmed

Ago1 and Ago2 differentially affect cell proliferation, motility and apoptosis when overexpressed in SH-SY5Y neuroblastoma cells.

AGO2 AGO1

4.71e-06276221846468
Pubmed

The association of AGO1 (rs595961G>A, rs636832A>G) and AGO2 (rs11996715C>A, rs2292779C>G, rs4961280C>A) polymorphisms and risk of recurrent implantation failure.

AGO2 AGO1

4.71e-06276231724726
Pubmed

Longitudinal Clinical Follow-up and Genetic Spectrum of Patients With Rod-Cone Dystrophy Associated With Mutations in PDE6A and PDE6B.

PDE6A PDE6B

4.71e-06276230998820
Pubmed

Comprehensive analysis of keratin gene clusters in humans and rodents.

KRT81 KRT83 KRT86

5.50e-061676315085952
Pubmed

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

AGO2 AGO1 AGO4

5.50e-061676320102707
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TNIK AKT3 AGO2 AGAP7P SIPA1L2 SYNGAP1

8.59e-0621876633378226
Pubmed

PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.

KRT81 KRT83 KRT86

9.47e-061976321285247
Pubmed

Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

AGO2 AGO1

1.41e-05376223665583
Pubmed

The roles of individual mammalian argonautes in RNA interference in vivo.

AGO2 AGO1

1.41e-05376224992693
Pubmed

New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene.

PDE6A PDE6B

1.41e-05376218849587
Pubmed

Structure of C3PO and mechanism of human RISC activation.

AGO2 TSN

1.41e-05376221552258
Pubmed

Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells.

AGO2 AGO1

1.41e-05376224086155
Pubmed

Argonaute2 is the catalytic engine of mammalian RNAi.

AGO2 AGO1

1.41e-05376215284456
Pubmed

Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.

AGO2 AGO1

1.41e-05376230201950
Pubmed

Genetic mapping demonstrates that the alpha-subunit of retinal cGMP-phosphodiesterase is not the site of the rd mutation.

PDE6A PDE6B

1.41e-0537622167232
Pubmed

Cyclic GMP-activated conductance of retinal photoreceptor cells.

PDE6A PDE6B

1.41e-0537622467600
Pubmed

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.

AGO2 AGO1

1.41e-05376217626790
Pubmed

Sequence data and chromosomal localization of human type I and type II hair keratin genes.

KRT81 KRT86

1.41e-0537627556444
Pubmed

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies.

AGO2 AGO1

1.41e-05376215908945
Pubmed

Sequences and differential expression of three novel human type-II hair keratins.

KRT83 KRT86

1.41e-0537629084137
Pubmed

cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits.

PDE6A PDE6B

1.41e-05376210373499
Pubmed

A TDG/CBP/RARα ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genes.

TDG CREBBP

1.41e-05376224394593
Pubmed

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain.

AGO2 AGO1

1.41e-05376217891150
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

ASH1L CC2D2A CEP126 SIPA1L2 DNAH1

2.22e-0515376510718198
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

BRD7 ASH1L ATAD2 CREBBP

2.27e-057576425593309
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

DMGDH COL12A1 CLIC5 ANK3 KAT8 ELP1 TSN MGLL NEB ATAD2 HYDIN EHD4

2.28e-051293761215342556
Pubmed

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.

AGO2 AGO1 AGO4

2.51e-052676319898466
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

AGO2 AGO1 KRT81 KRT83 KRT86 ELP1

2.64e-0526676619380743
Pubmed

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression.

AGO2 AGO1

2.82e-05476220671708
Pubmed

Retroviral GAG proteins recruit AGO2 on viral RNAs without affecting RNA accumulation and translation.

AGO2 AGO1

2.82e-05476221948796
Pubmed

Identification of novel argonaute-associated proteins.

AGO2 AGO1

2.82e-05476216289642
Pubmed

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies.

AGO2 AGO1

2.82e-05476215937477
Pubmed

Strain distribution pattern in AXB and BXA recombinant inbred strains for loci on murine chromosomes 10, 13, 17, and 18.

PDE6A CSF1R

2.82e-0547628094988
Pubmed

Mutation analysis of BRCA1, BRCA2, PALB2 and BRD7 in a hospital-based series of German patients with triple-negative breast cancer.

BRCA2 BRD7

2.82e-05476223110154
Pubmed

AIPL1, a protein associated with childhood blindness, interacts with alpha-subunit of rod phosphodiesterase (PDE6) and is essential for its proper assembly.

PDE6A PDE6B

2.82e-05476219758987
Pubmed

Argonaute proteins: potential biomarkers for human colon cancer.

AGO2 AGO4

2.82e-05476220146808
Pubmed

Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.

CFAP70 DNAH1

2.82e-05476237934199
Pubmed

Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.

TDG CREBBP

2.82e-05476224532795
Pubmed

Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.

AGO2 AGO1

2.82e-05476222647351
Pubmed

Identification of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6.

PDE6A PDE6B

2.82e-05476223033484
Pubmed

CBP-mediated post-translational N-glycosylation of BRCA2.

BRCA2 CREBBP

2.82e-05476219578754
Pubmed

Rod phosphodiesterase-6 (PDE6) catalytic subunits restore cone function in a mouse model lacking cone PDE6 catalytic subunit.

PDE6A PDE6B

2.82e-05476221799013
Pubmed

Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.

KRT81 KRT86

2.82e-0547629457912
Pubmed

Mammalian microtubule P-body dynamics are mediated by nesprin-1.

AGO2 SYNE1

2.82e-05476224862572
Pubmed

Genetic Rescue Reverses Microglial Activation in Preclinical Models of Retinitis Pigmentosa.

PDE6A PDE6B

2.82e-05476230001913
Pubmed

A Requirement for Argonaute 4 in Mammalian Antiviral Defense.

AGO1 AGO4

2.82e-05476232049003
Pubmed

MxA interacts with and is modified by the SUMOylation machinery.

BRD7 PSD3 TDG

2.82e-052776325447205
Pubmed

Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation.

PDE6B CREBBP

4.69e-05576217656371
Pubmed

Quantitative functions of Argonaute proteins in mammalian development.

AGO2 AGO1

4.69e-05576222474261
Cytoband12q13

KRT81 KRT83 KRT86

2.30e-047176312q13
GeneFamilyArgonaute/PIWI family

AGO2 AGO1 AGO4

1.32e-068533408
GeneFamilyKeratins, type II

KRT81 KRT83 KRT86

6.62e-0527533609
GeneFamilyDyneins, axonemal

DNAH17 DNAH1

1.11e-0317532536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT8 CREBBP

1.11e-0317532486
GeneFamilyPhosphodiesterases

PDE6A PDE6B

2.23e-0324532681
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT3 PSD2 PSD3 AGAP7P

3.10e-03206534682
CoexpressionHUPER_BREAST_BASAL_VS_LUMINAL_DN

SCCPDH KRT81 KRT86 ENO2

2.46e-0558764M5505
CoexpressionGSE14350_TREG_VS_TEFF_UP

AGO1 SYNE1 ASH1L RNF213 PRDM15 DYRK2

2.50e-05199766M3417
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

AGO1 RNF213 GREB1 ENO2 ARID5A MX2

2.50e-05199766M9180
CoexpressionGSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN

SCCPDH CSF1R RBL1 DBF4 MARCHF6 GGPS1

2.50e-05199766M3070
CoexpressionGSE10325_CD4_TCELL_VS_MYELOID_UP

TNIK AKT3 ANK3 SYNE1 ENO2 DYRK2

2.50e-05199766M3078
CoexpressionGSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_DN

COL12A1 AGO1 SYNE1 RCBTB2 TSN HYDIN

2.57e-05200766M3222
CoexpressionGARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_DN

CEP126 PRDM15 DYRK2

4.54e-0524763M19520
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_PROJECTION_NEURONS

TNIK AKT3 MGLL HERC3 DYRK2

6.95e-05147765MM414
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

FAP AKT3 COL12A1 RNF213 GPNMB

1.71e-04178765M17079
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

ANK3 BRCA2 RNF213 NEB EHD4

1.94e-04183765M2993
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP

TNIK AKT3 CYP2E1 GUCY2C CEP126 PKHD1L1

1.99e-04290766M11616
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN

AGO1 AGO4 PSD3 ELP1 TDG DYRK2

2.14e-04294766M41112
CoexpressionBOYAULT_LIVER_CANCER_SUBCLASS_G3_UP

DNAJC10 BRD7 TSN TDG PUS7

2.31e-04190765M18436
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

TNIK NANP RBL1 DBF4 MARCHF6 BRD7 ATAD2

2.66e-04434767M15150
CoexpressionGSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN

AGO1 BRCA2 KIAA0513 DBF4 DNAH17

2.67e-04196765M8717
CoexpressionGSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP

TNIK KIAA0513 CREBBP MX2 DYRK2

2.80e-04198765M5293
CoexpressionGSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN

ANK3 KIAA0513 PDE6B KAT8 MX2

2.86e-04199765M4620
CoexpressionGSE360_DC_VS_MAC_T_GONDII_DN

AKT3 DBF4 RCBTB2 GPNMB ENO2

2.86e-04199765M5184
CoexpressionGSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP

TNIK AGO2 RNF213 GGPS1 DYRK2

2.86e-04199765M9269
CoexpressionGSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN

COL12A1 NANP DBF4 GREB1 PRDM15

2.86e-04199765M5707
CoexpressionGSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP

AGO1 AGO4 VPS39 CC2D2A CEP126

2.86e-04199765M6970
CoexpressionGSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_DN

AGO2 TEX47 KRT81 DNAH17 HERC3

2.93e-04200765M7799
CoexpressionGSE13229_IMM_VS_MATURE_NKCELL_UP

LIAS PSD2 BRCA2 RNF213 TSN

2.93e-04200765M3205
CoexpressionGSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP

AGO1 KIAA0513 RCBTB2 ARID5A DYRK2

2.93e-04200765M6606
CoexpressionGSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN

KIAA0513 KRT86 MAP2K7 MX2 EHD4

2.93e-04200765M9597
CoexpressionGSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN

AKT3 RCBTB2 NEB MX2 DYRK2

2.93e-04200765M6570
CoexpressionGSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN

AKT3 RNF213 GPNMB ARID5A DYRK2

2.93e-04200765M6563
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

TNIK MARCHF6 HERC3 ENO2 DYRK2

2.93e-04200765M9889
CoexpressionGSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN

CLIC5 ELP1 TDG HERC3 GPNMB

2.93e-04200765M8427
CoexpressionGSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN

ANK3 KRT81 NEB ARID5A MX2

2.93e-04200765M6789
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN

RBL1 RNF213 CMYA5 ARID5A DYRK2

2.93e-04200765M9837
CoexpressionGSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP

TNIK DNAJC10 RBL1 GREB1 ENO2

2.93e-04200765M9203
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

AKT3 DNAH17 ARID5A MX2 DYRK2

2.93e-04200765M6035
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

TNIK NANP RBL1 DBF4 MARCHF6 BRD7 ATAD2

3.22e-04448767MM1044
ToppCelldroplet-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT81 KRT83 KRT86 CFAP70 DYRK2

9.71e-07104765a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK AKT3 ANK3 SYNE1 ASH1L RNF213

1.17e-06199766f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

VILL GUCY2C TSN GREB1 NEB

9.62e-061667656a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

CSF1R PSD3 MGLL GPNMB SIPA1L2

1.02e-051687658ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE6B CEP126 CFAP70 HYDIN DNAH1

1.05e-051697658bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

CPA5 KRT86 RNF213 CFAP70 MX2

1.54e-05183765058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

CPA5 KRT86 RNF213 CFAP70 MX2

1.54e-051837657a6f18246c39864479e114f698581f667fa9c600
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NEB PKHD1L1 HYDIN DNAH1

1.58e-051847652cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMGDH AKT3 ANK3 ENO2 DYRK2

1.58e-05184765bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NEB PKHD1L1 HYDIN DNAH1

1.58e-05184765ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NEB PKHD1L1 HYDIN DNAH1

1.58e-051847652b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAP CYP2E1 PON1 CMYA5 ENO2

1.67e-0518676526458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAP CYP2E1 PON1 CMYA5 ENO2

1.67e-05186765a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDE6B KRT81 KRT86 ELP1 MGLL

1.71e-05187765c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

1.85e-051907659ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

1.85e-05190765833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SCCPDH PDE6B KRT81 ELP1 MGLL

1.89e-05191765d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK AKT3 ANK3 SYNE1 RNF213

1.99e-051937659337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.04e-05194765b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.04e-051947657a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ANK3 SYNE1 CEP126 CFAP70 HYDIN

2.09e-05195765fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ANK3 SYNE1 CEP126 CFAP70 HYDIN

2.09e-05195765eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.09e-051957653486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL12A1 SCCPDH CLIC5 MGLL GPNMB

2.09e-051957657e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.14e-05196765d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.20e-051977656865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.20e-0519776591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK AKT3 ANK3 SYNE1 RNF213

2.20e-0519776557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.20e-0519776571fea4aa6ce96c7693fa94792d08770622873850
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK AKT3 ANK3 SYNE1 RNF213

2.20e-05197765e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.20e-05197765e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.20e-05197765d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 CC2D2A CEP126 CFAP70 HYDIN

2.25e-05198765ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

DMGDH CEP126 CFAP70 HYDIN DNAH1

2.25e-051987656d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CLIC5 SYNE1 PON1 SIPA1L2

2.30e-05199765b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CLIC5 SYNE1 PON1 SIPA1L2

2.30e-05199765c972d3036151403f26fa9d6271520639c281ab84
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAP COL12A1 ANK3 CAPN6 GPNMB

2.36e-05200765747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAP COL12A1 ANK3 CAPN6 GPNMB

2.36e-05200765de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLIC5 VILL CAPN6 DNAH1

1.36e-041537645501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

CYP2E1 SYNE1 ASH1L RNF213

1.47e-04156764afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BRCA2 CC2D2A CFAP70 HYDIN

1.51e-04157764410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NANP KRT81 KRT86 PRDM15

1.54e-0415876474aa4f75307575ac3b2b1aa9f727753692f88742
ToppCellSevere-Lymphoid-NK-Proliferating_T|Severe / Condition, Lineage, Cell class and cell subclass

RBL1 KRT81 KRT86 HERC3

1.62e-04160764cb2276d9bd78508644420e9580d3c17b914224cb
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 HERC3 NEB ATAD2

1.62e-041607645cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM7 NEB PKHD1L1 HYDIN

1.70e-04162764bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Marrow-BM-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R CYP2E1 KIAA0513 VILL

1.70e-0416276476e289ad9fd3694f77fd0d19e74c1cb8e87b8094
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE6B KRT81 KRT86 NEB

1.74e-04163764e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE6B KRT81 KRT86 NEB

1.74e-04163764ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE6B KRT81 KRT86 NEB

1.74e-04163764ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEP126 CFAP70 HYDIN DNAH1

2.00e-04169764fba841664939c771881ba97f14ef1df6635c04ff
ToppCellsevere-Myeloid-Eosinophils|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK SCCPDH KRT81 SYNE1

2.04e-04170764863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAP COL12A1 BRCA2 ATAD2

2.09e-04171764b0373ed8283ee1792b6a490bff93906546978593
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TNIK AKT3 SYNE1 KRT86

2.09e-04171764adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAP COL12A1 BRCA2 ATAD2

2.09e-04171764b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK SCCPDH KRT81 SYNE1

2.09e-041717645c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNE1 KRT86 RNF213 NEB

2.14e-04172764f3c16a62eba1ed190318beee131c71c5150b266a
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|367C / Donor, Lineage, Cell class and subclass (all cells)

DMGDH KRT81 KRT86 BRD7

2.14e-041727646379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL12A1 PSD2 DBF4 ATAD2

2.14e-04172764c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLIC5 NANP DNAH17 EHD4

2.14e-04172764490745024730df6357f6c2b81d7a64e21557c0d5
ToppCelldroplet-Fat-Scat-21m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIC5 BRCA2 MGLL NEB

2.18e-04173764f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FAP DNAH17 RNF213 MX2

2.18e-041737645b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAP DNAH17 RNF213 MX2

2.18e-04173764bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAP DNAH17 RNF213 MX2

2.18e-04173764a6e73a40b0d5356564a594053e772f9d061a5919
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAP DNAH17 RNF213 MX2

2.18e-04173764a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FAP DNAH17 RNF213 MX2

2.18e-041737641edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FAP DNAH17 RNF213 MX2

2.18e-04173764c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLIC5 KIAA0513 ATAD2 EHD4

2.33e-04176764269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMGDH CYP2E1 KRT81 KRT86

2.33e-04176764238244294d08975df6bfa26b2b437db3654408ae
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 ELP1 RNF213 MTREX

2.38e-04177764d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 ELP1 RNF213 MTREX

2.38e-04177764f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellSevere_COVID-19-Myeloid-Neutrophil|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

FAP DNAH17 RNF213 MX2

2.38e-04177764a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

SYNE1 ELP1 RNF213 MTREX

2.38e-041777646978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 ELP1 RNF213 MTREX

2.38e-04177764936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 ELP1 RNF213 MTREX

2.38e-04177764d5aeda113afaa2425874394610344570c9078478
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLIC5 RBL1 ATAD2 EHD4

2.38e-041777640e74980a7686c31fcf1476b8f19a3392541df240
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIC5 SYNE1 ASH1L MX2

2.43e-0417876401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

ANK3 RNF213 ARID5A MX2

2.43e-04178764ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ANK3 BRCA2 RNF213 MX2

2.49e-04179764af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK CSF1R DBF4 NEB

2.49e-0417976430efe1f0394c0edb27b91890b5c4637b73cbc5ec
ToppCell367C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KRT81 KAT8 MGLL CEP126

2.49e-041797645aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

TNIK KRT81 KRT83 KRT86

2.49e-041797641526a130565a97c291a25a7a988089bffc1515c1
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 ARID5A

2.49e-04179764dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CEP126 CFAP70 HYDIN DNAH1

2.54e-04180764bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CC2D2A CEP126 CFAP70 HYDIN

2.54e-041807641f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DMGDH CYP2E1 KRT81 KRT86

2.54e-0418076427672ac6a02172a31851f18decb9acffa8f5a703
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

CSF1R PSD3 GPNMB GGPS1

2.54e-04180764daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TNIK SCCPDH KRT81 SYNE1

2.54e-04180764ac03812b1409435c55d323a7516deeac82bd3509
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

AKT3 ANK3 ASH1L RNF213

2.59e-04181764f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 SYNE1 PON1 SIPA1L2

2.59e-041817645f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 SYNE1 PON1 SIPA1L2

2.59e-04181764c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 CAPN6 GREB1 CMYA5

2.65e-041827643dfa9187e9d2bab1d199079d29209c4648220ada
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ANK3 GPNMB ENO2

2.65e-041827646fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

KIAA0513 RNF213 MGLL EHD4

2.65e-041827647af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 HERC3 GPNMB ATAD2

2.65e-0418276457f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

KIAA0513 RNF213 MGLL EHD4

2.65e-04182764e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R DNAJC10 ATAD2 EHD4

2.65e-04182764bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYP2E1 KRT81 KRT83 KRT86

2.65e-041827646bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellURO-Lymphocyte-T_NK-dnT|URO / Disease, Lineage and Cell Type

AKT3 KIAA0513 SWT1 SYNGAP1

2.65e-04182764f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

SYNE1 ELP1 RNF213 MTREX

2.70e-0418376422bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK ANK3 RBL1 DYRK2

2.70e-04183764f2ef110bf29b1a8276ef216238363e542db262c1
DrugAC1L1BIT

LIAS KRT81 KRT83 SYNE1 KRT86

1.72e-0660765CID000001457
Drugtrioxane

KRT81 KRT83 SYNE1

9.98e-0613763CID000008081
Drugmelicopicine

KRT81 KRT83

1.10e-052762CID000101253
Drugtebuquine

KRT81 KRT83

1.10e-052762CID000071991
Drug3,5-di-O-galloylquinic acid

KRT81 KRT83

1.10e-052762CID000460896
Drug4-hydroxy-2-nonenal

AGO2 CSF1R RBL1 DBF4 KAT8 PON1 ELP1 HERC3 FBXO39 CREBBP ARID5A MX2

1.25e-057987612ctd:C027576
Drugmusk xylene

LIAS CSF1R MX2

2.35e-0517763CID000062329
DrugATBI

KRT81 KRT83 KRT86

2.81e-0518763CID000505862
Drugsulfonamide-3

KRT81 KRT83

3.29e-053762CID009847197
Drugcycloguanil

CYP2E1 KRT81 KRT83

3.91e-0520763CID000009048
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A

PDE6B DNAH17 ELP1 HERC3 GPNMB NEB

5.00e-051967665088_UP
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; MCF7; HT_HG-U133A

ANK3 KRT83 ASH1L PSD3 ELP1 CREBBP

5.14e-051977665974_UP
DrugLymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A

PDE6A CSF1R CLIC5 CYP2E1 DNAH17 MX2

5.14e-051977663514_UP
DrugMinoxidil [38304-91-5]; Up 200; 19.2uM; MCF7; HT_HG-U133A

AGO4 CSF1R PDE6B KRT83 KAT8 PSD3

5.14e-051977664800_UP
DrugBrinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A

AGO4 PDE6B DNAH17 PSD3 GPNMB MAP2K7

5.44e-051997663230_UP
DrugTelenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A

TNIK CLIC5 CYP2E1 PDE6B KAT8 MAP2K7

5.59e-052007665521_UP
Drugpyriproxyfen

KRT81 KRT83 KRT86

6.03e-0523763CID000091753
DrugAC1L2K1Q

CYP2E1 KRT81 KRT83

6.03e-0523763CID000022258
DrugLactupicrin

KRT81 KRT83

6.57e-054762CID000174880
Druglactucin

KRT81 KRT83

6.57e-054762CID000442266
Drugsalsalate

LIAS KRT81 KRT83 KRT86

7.06e-0566764CID000005161
Drughomocysteine thiolactone

KRT81 KRT83 KRT86 PON1 MGLL

7.78e-05131765CID000107712
Drugp-aminophenol

CYP2E1 KRT81 KRT83 PON1

7.94e-0568764CID000000403
DiseaseBeaded hair

KRT81 KRT83 KRT86

1.64e-083763cv:C0546966
DiseaseMONILETHRIX

KRT81 KRT83 KRT86

1.64e-083763158000
Diseasemonilethrix (is_implicated_in)

KRT81 KRT83 KRT86

1.64e-083763DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT83 KRT86

6.56e-084763C0546966
Diseasehair disease (is_implicated_in)

KRT81 KRT86

6.55e-062762DOID:421 (is_implicated_in)
Diseasealcohol use disorder (implicated_via_orthology)

AKT3 PSD2 CLIC5 BRD7 PSD3 CREBBP

1.15e-05195766DOID:1574 (implicated_via_orthology)
DiseaseSchizophrenia

TNIK ANK3 CYP2E1 VPS39 KAT8 PSD3 PON1 CMYA5 MAP2K7 ENO2 SYNGAP1

1.57e-058837611C0036341
Diseasepyridoxamine measurement

MGLL NEB

1.96e-053762EFO_0021837
DiseaseMEDULLOBLASTOMA

BRCA2 ELP1

9.75e-056762155255
DiseaseMedulloblastoma

BRCA2 ELP1

9.75e-056762cv:C0025149
Diseasecolorectal carcinoma (is_marker_for)

CSF1R BRCA2 BRD7

1.20e-0437763DOID:0080199 (is_marker_for)
Diseaseinfertility (implicated_via_orthology)

CSF1R BRCA2

1.36e-047762DOID:5223 (implicated_via_orthology)
Diseasedual specificity protein phosphatase 13 isoform A measurement

PON1 EHD4

1.81e-048762EFO_0801549
DiseaseParkinson disease

COL12A1 DNAH17 ASH1L GPNMB SIPA1L2 PRDM15

1.82e-04321766MONDO_0005180
DiseaseGlioma

BRCA2 ELP1

2.33e-049762cv:C0017638
Diseasemedulloblastoma (is_implicated_in)

BRCA2 ELP1

2.91e-0410762DOID:0050902 (is_implicated_in)
DiseaseMammary Carcinoma, Human

CSF1R BRCA2 VPS39 SYNE1 ELP1 GPNMB MAP2K7

4.11e-04525767C4704874
DiseaseMammary Neoplasms, Human

CSF1R BRCA2 VPS39 SYNE1 ELP1 GPNMB MAP2K7

4.11e-04525767C1257931
DiseaseMammary Neoplasms

CSF1R BRCA2 VPS39 SYNE1 ELP1 GPNMB MAP2K7

4.21e-04527767C1458155
DiseaseHematologic Neoplasms

CSF1R PON1

4.25e-0412762C0376545
DiseaseBreast Carcinoma

CSF1R BRCA2 VPS39 SYNE1 ELP1 GPNMB MAP2K7

4.76e-04538767C0678222
Diseaseplasma beta-amyloid 1-42 measurement

ANK3 KRT86

5.01e-0413762EFO_0005660
Diseaseasthma, response to diisocyanate

COL12A1 KRT81 KRT86 GREB1 CMYA5

5.77e-04261765EFO_0006995, MONDO_0004979
DiseaseLung Neoplasms

ANK3 BRCA2 CYP2E1 PON1 MAP2K7

6.18e-04265765C0024121
DiseaseMalignant neoplasm of lung

ANK3 BRCA2 CYP2E1 PON1 MAP2K7

6.29e-04266765C0242379
Diseasenasopharynx carcinoma (is_implicated_in)

CSF1R CYP2E1

6.73e-0415762DOID:9261 (is_implicated_in)
Diseaseschizophrenia (implicated_via_orthology)

AKT3 MAP2K7 SYNGAP1

7.30e-0468763DOID:5419 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_marker_for)

FAP AKT3 CSF1R BRD7

9.67e-04169764DOID:3908 (is_marker_for)
DiseaseIntellectual Disability

AGO1 SYNE1 KAT8 ASH1L PUS7 SYNGAP1

1.04e-03447766C3714756
DiseaseProstatic Neoplasms

DNAJC10 BRCA2 CYP2E1 ASH1L PON1 GREB1 CREBBP

1.05e-03616767C0033578
DiseaseMalignant neoplasm of prostate

DNAJC10 BRCA2 CYP2E1 ASH1L PON1 GREB1 CREBBP

1.05e-03616767C0376358
Diseasesex interaction measurement, bilirubin measurement

COL12A1 PSD3

1.46e-0322762EFO_0004570, EFO_0008343
Diseasemalignant astrocytoma (is_marker_for)

AKT3 BRD7

1.60e-0323762DOID:3069 (is_marker_for)
Diseasecolon adenocarcinoma (is_implicated_in)

CSF1R MAP2K7

2.04e-0326762DOID:234 (is_implicated_in)
DiseaseMicronuclei, Chromosome-Defective

CYP2E1 PON1

2.04e-0326762C1449861
DiseaseMicronuclei, Genotoxicant-Induced

CYP2E1 PON1

2.04e-0326762C1449862
Diseasemean corpuscular hemoglobin concentration

AGO2 AGO4 RBL1 PSD3 CC2D2A AGAP7P NEB MAP2K7 ENO2

2.11e-031105769EFO_0004528
Diseaseretinitis pigmentosa (implicated_via_orthology)

PDE6A PDE6B

2.20e-0327762DOID:10584 (implicated_via_orthology)
Diseaseprostate carcinoma in situ (is_marker_for)

CSF1R MAP2K7

2.37e-0328762DOID:8634 (is_marker_for)
Diseasebipolar disorder (is_implicated_in)

ANK3 SYNE1

2.54e-0329762DOID:3312 (is_implicated_in)
Diseaseselenium measurement

DMGDH CMYA5

2.54e-0329762EFO_0006331

Protein segments in the cluster

PeptideGeneStartEntry
RAQDKVHYYIKLKDL

TDG

281

Q13569
KIYKAVEKLGAYELV

ARID5A

91

Q03989
LKKEKLEYTPGEHEY

ASH1L

2011

Q9NR48
DKHLYEEYVEKPLKL

BRD7

11

Q9NPI1
KIKGIHDEKYVELFI

ADAM7

191

Q9H2U9
VTVISLLVYKKHKEY

GPNMB

511

Q14956
DIPKIDVYHYEVDIK

AGO1

46

Q9UL18
YHLLAEKIYKIQKEL

CREBBP

651

Q92793
HEILIGYLEYVKKLG

CREBBP

1451

Q92793
SKIDLHKYLTVKDYL

ATAD2

1036

Q6PL18
KIDVYHYDVDIKPEK

AGO4

41

Q9HCK5
HIDDIRYYIEQKKKE

DBF4

171

Q9UBU7
LHVVKIVAKKYRNYD

CLIC5

351

Q9NZA1
AEVYHTLKGVIKDKY

ENO2

186

P09104
KIDIYHYELDIKPEK

AGO2

51

Q9UKV8
YLHSGKIVYRDLKLE

AKT3

261

Q9Y243
DGKYIYAHKVLLKIR

RCBTB2

401

O95199
HGYKAVKEALLDYKD

CYP2E1

81

P05181
VDTKKYKVLLTYDTH

GUCY2C

386

P25092
EDEKKGEKIYLYTHL

KIAA0513

281

O60268
LHVLVVKEYEMAIYK

GREB1

1571

Q4ZG55
LKIYEGAYHVLHKEL

MGLL

261

Q99685
KLYKVNLKVKHVEYD

HERC3

596

Q15034
VKYVDKIHIGNYEID

KAT8

176

Q9H7Z6
VLEGYKKKYEEEVSL

KRT86

186

O43790
EEKNLDLLYKYIVHK

DYNC1LI2

276

O43237
KDAVEALYKVHGIEY

CPA5

351

Q8WXQ8
IVKALYYLKEKHGVI

MAP2K7

226

O14733
YYLKEKHGVIHRDVK

MAP2K7

231

O14733
YKVIDYILHGKEDIK

PDE6A

316

P16499
IVFYKVIDYVLHGKE

PDE6B

311

P35913
YVKKFGRYLEHLEVK

FBXO39

81

Q8N4B4
VIKLLQSKYHYKEEA

NANP

31

Q8TBE9
KRLYEHIKNDKYLVG

MARCHF6

871

O60337
HLKVEEYITPEKFKY

LIAS

316

O43766
IDKYLKRYEKAIGHL

ELP1

936

O95163
LAKVHAYIISYLKKE

EHD4

306

Q9H223
IDIKKYCVHYLEDVG

GGPS1

241

O95749
GVLDYDEEKKLYLVH

DNAH1

306

Q9P2D7
GVDYKNIHLEKKYVR

CSF1R

696

P07333
YIYITEENKPHVKAK

HYDIN

3541

Q4G0P3
ELETLYKKAVKYVHS

CC2D2A

376

Q9P2K1
IYAIHDETSYKGKKI

BRCA2

591

P51587
KIYIDCYEIIEKDIK

COL12A1

2661

Q99715
YIKIGDKEVEYHPKF

DNAH17

3511

Q9UFH2
KESKYEHGYLKALII

CEP126

581

Q9P2H0
LGLIYLEEKEYEKAK

CFAP70

1006

Q5T0N1
GYVIKEIHYRKGKDA

CMYA5

251

Q8N3K9
LGDYMKYIHKKEIDL

AGAP7P

296

Q5VUJ5
KKVLYREYVVKEGDH

ANK3

2926

Q12955
KKIHYDSIKLYEKLE

DMGDH

106

Q9UI17
YEIHHGKKILYDILA

DNAJC10

431

Q8IXB1
ELVEEKYKLFGELYK

CAPN6

206

Q9Y6Q1
DHVAYRYEVLKVIGK

DYRK2

216

Q92630
VLEGYKKKYEEEVAL

KRT83

191

P78385
TLYKVLLDYIGHVKD

TEX47

106

Q8TBZ9
DGKYVYIAELLAHKI

PON1

231

P27169
IHEYLQKYKGFKIDI

SYNE1

6946

Q8NF91
KYHEKAADKGVYIIG

SCCPDH

136

Q8NBX0
VEAKGIKEHYFKPYI

RBL1

261

P28749
EYLKHIMEVHKEKGY

PRDM15

1006

P57071
KTEDREGKKYIVAYH

PUS7

221

Q96PZ0
KVKRYIIEHIDLGAY

SIPA1L2

471

Q9P2F8
EKRKLKSDHTDVLYY

SWT1

51

Q5T5J6
KDGYKHIHYIKDTVE

FAP

371

Q12884
KLLLKYSFHDVKDYI

RNF213

4136

Q63HN8
LEGCIHYKVVKYERI

TNIK

1141

Q9UKE5
HYKVVKYERIKFLVI

TNIK

1146

Q9UKE5
KEAIGFYEPIVKKHY

TTC30B

476

Q8N4P2
LGKEIEEYIHKPKYC

MTREX

636

P42285
AHIEREEYKLKEYSK

SYNGAP1

1171

Q96PV0
IKSKEAEEYRLKEHY

PSD2

686

Q9BQI7
IHLQKGKEYYIEILL

PKHD1L1

451

Q86WI1
VRLYHVYEKGKDLVV

VILL

251

O15195
KEAIGFYEPIVKKHY

TTC30A

476

Q86WT1
KLVDLYYQEKKHLEV

TTC37

121

Q6PGP7
EYKLKDHYLEFEKTR

PSD3

966

Q9NYI0
LKKAHKYSELIILYE

VPS39

496

Q96JC1
KYSELIILYEKKGLH

VPS39

501

Q96JC1
DGLKYDVKKVEEVVY

TSN

196

Q15631
VLEGYKKKYEEEVSL

KRT81

186

Q14533
IHEEVEKYEKQYRGK

MX2

476

P20592
EARYKDLYVKDVLGH

NEB

666

P20929