Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentchromatin

CUX2 CAPN2 PBX4 RELB CHD7 GATA5 RFX2 ATF6B ZEB2 CREB3L1 NUFIP1 FANCA NKX1-2 RIF1 ARID1B TET1 ANKRD17 ELF3 AFF4 FOXE3 TBX2

8.70e-05148011921GO:0000785
DomainFAM21

WASHC2C WASHC2A

3.82e-0521162IPR027308
DomainCAP-ZIP_m

WASHC2C WASHC2A

1.14e-0431162PF15255
DomainFAM21/CAPZIP

WASHC2C WASHC2A

1.14e-0431162IPR029341
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A SGIP1 TRIOBP CHD7 ZNF318 DNAJC6 ATF6B ZEB2 DLGAP3 EPS15L1 SHANK2 FBXO41 ANKRD17 CTBP2 CDH2 AFF4 TP53BP1

4.28e-089631211728671696
Pubmed

Selection system for genes encoding nuclear-targeted proteins.

TRIOBP ZNF318 ZEB2 EPS15L1

1.36e-071412149853615
Pubmed

Interaction network of human early embryonic transcription factors.

KMT2B SCAMP3 CHD7 MBD6 ZEB2 ARID1B TET1 CTBP2 CDH2 TBX2

4.53e-073511211038297188
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERBB2 KMT2B MAN2B1 NLRX1 RELB MBD6 WASHC2A FANCA EPS15L1 FASN SHANK2 SUGP2 MTMR14 ULK1 RAB11FIP3

7.20e-0611051211535748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERBB2 PSD MAP1A ZNF318 NUFIP1 ARHGAP4 ZNF469 ARID1B SUGP2 ANKRD17 ELF3 MAIP1 AFF4 LRRC41 TBX2

8.10e-0611161211531753913
Pubmed

KIF26B and CREB3L1 Derived from Immunoscore Could Inhibit the Progression of Ovarian Cancer.

KIF26B CREB3L1

1.20e-052121238380081
Pubmed

53BP1-RIF1: sculpting the DNA repair focus in 3D.

RIF1 TP53BP1

1.20e-052121231792447
Pubmed

Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.

ERBB2 FASN

1.20e-052121226107737
Pubmed

Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.

ERBB2 FASN

1.20e-052121225674245
Pubmed

ESE-1 Knockdown Attenuates Growth in Trastuzumab-resistant HER2+ Breast Cancer Cells.

ERBB2 ELF3

1.20e-052121229187433
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

1.20e-052121220827171
Pubmed

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.

ERBB2 FASN

1.20e-052121227714708
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

1.20e-052121236717248
Pubmed

ErbB2 activation of ESX gene expression.

ERBB2 ELF3

1.20e-052121212032832
Pubmed

Effect of N-cadherin misexpression by the mammary epithelium in mice.

ERBB2 CDH2

1.20e-052121215838877
Pubmed

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.

ERBB2 FASN

1.20e-052121215235125
Pubmed

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

CHD7 TP53BP1

1.20e-052121233188175
Pubmed

TET1 mediated m5C modification of RelB aggravates cerebral ischemia/reperfusion-induced neuroinflammation through regulating microglia polarization.

RELB TET1

1.20e-052121238705503
Pubmed

Differential expression of fatty acid synthase (FAS) and ErbB2 in nonmalignant and malignant oral keratinocytes.

ERBB2 FASN

1.20e-052121218528705
Pubmed

53BP1/RIF1 signaling promotes cell survival after multifractionated radiotherapy.

RIF1 TP53BP1

1.20e-052121231822909
Pubmed

Variants in NEB and RIF1 genes on chr2q23 are associated with skeletal muscle index in Koreans: genome-wide association study.

NEB RIF1

1.20e-052121233674626
Pubmed

The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress.

RIF1 TP53BP1

1.20e-052121233141022
Pubmed

The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma.

PCIF1 CTBP2

1.20e-052121237643007
Pubmed

Expression status of fatty acid synthase (FAS) but not HER2 is correlated with the differentiation grade and prognosis of esophageal carcinoma.

ERBB2 FASN

1.20e-052121223419663
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

1.20e-052121215847701
Pubmed

CD40 ligand-mediated activation of the de novo RelB NF-kappaB synthesis pathway in transformed B cells promotes rescue from apoptosis.

RELB CD40

1.20e-052121217446175
Pubmed

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

RIF1 TP53BP1

1.20e-052121223333305
Pubmed

FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.

ERBB2 FASN

1.20e-052121226936618
Pubmed

Molecular and biochemical characterization of a novel gamma-interferon-inducible protein.

IFNGR2 IFI30

1.20e-05212123136170
Pubmed

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

RIF1 TP53BP1

1.20e-052121223306437
Pubmed

Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer.

ERBB2 FASN

1.20e-052121225433947
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

KMT2B CHD7 ZNF318 ZEB2 FASN TET1 ANKRD17 CTBP2 DCP1A

1.66e-05418121934709266
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KMT2B WASHC2C CHD7 ZNF318 ADARB1 RIF1 EPS15L1 FASN SUGP2 ANKRD17 TP53BP1 DCP1A

1.73e-057741211215302935
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

CUX2 MAP1A RELB SCAMP3 CHD7 ZNF469 UBQLN3 CLINT1 WNK4

2.07e-05430121935044719
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2B ZNF318 EPS15L1 FASN ARID1B SUGP2 TET1 CLINT1 TP53BP1 DCP1A

2.34e-055491211038280479
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

WASHC2C MAP1A ZNF318 NEDD1 RIF1 EPS15L1 FASN SUGP2 ANKRD17 CLINT1 AFF4 TP53BP1 DCP1A

2.36e-059341211333916271
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SALL3 WASHC2C NRDC CHD7 ZNF318 WASHC2A ARID1B TET1 ANKRD17 AFF4 TP53BP1 SERTAD3 DCP1A RAB11FIP3

2.57e-0510841211411544199
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

EPS15L1 FASN CLINT1 DCP1A

2.62e-0549121431762063
Pubmed

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.

ERBB2 FASN

3.59e-053121218211286
Pubmed

Fatty acid synthase, Her2/neu, and E2F1 as prognostic markers of progression in non-muscle invasive bladder cancer.

ERBB2 FASN

3.59e-053121230684846
Pubmed

Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration.

ZEB2 PROS1

3.59e-053121236951067
Pubmed

External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator.

ERBB2 ELF3

3.59e-053121212242338
Pubmed

AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.

ULK1 AFF4

3.59e-053121237731335
Pubmed

A deletion in a cis element of Foxe3 causes cataracts and microphthalmia in rct mice.

CDH2 FOXE3

3.59e-053121222002806
Pubmed

Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.

KMT2B TET1

3.59e-053121231844322
Pubmed

TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.

RIF1 TP53BP1

3.59e-053121228241136
Pubmed

Genetics of susceptibility to leishmaniasis in mice: four novel loci and functional heterogeneity of gene effects.

IFNGR2 CD40

3.59e-053121216511555
Pubmed

Slc44a2 deletion alters tetraspanin and N-cadherin expression: Reduced adhesion and enhanced proliferation in cultured mesenchymal lung cells.

SLC44A2 CDH2

3.59e-053121234371293
Pubmed

EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin.

ERBB2 CDH2

3.59e-053121219033391
Pubmed

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.

ZEB2 CDH2

3.59e-053121224165969
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNA1A SGIP1 WASHC2C MAP1A CAPN2 TRIOBP WASHC2A PTPN2 DLGAP3 EPS15L1 SHANK2 SUGP2 FBXO41 TP53BP1

4.40e-0511391211436417873
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

RELB RFX2 ZEB2 RIF1 FASN SUGP2 ANKRD17 CTBP2 TP53BP1 LRRC41 DCP1A TBX2

4.66e-058571211225609649
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ERBB2 KIF26B DZIP1 STIL DNAH7 CARD8 MEX3C TET1 ANKRD17 CLINT1 WNK4 DCP1A

4.88e-058611211236931259
Pubmed

Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.

ZEB2 CDH2 FOXE3

5.22e-0521121324161570
Pubmed

Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1.

INSM2 CTBP2 TBX2

6.03e-0522121330305733
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

CACNA1A KMT2B PCDH9 WNK4

6.65e-0562121416147992
Pubmed

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

MAN2B1 WASHC2C WASHC2A

6.91e-0523121331748650
Pubmed

Cav2.1 in cerebellar Purkinje cells regulates competitive excitatory synaptic wiring, cell survival, and cerebellar biochemical compartmentalization.

CACNA1A GRIN2C

7.17e-054121222279216
Pubmed

Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.

ERBB2 FASN

7.17e-054121223725225
Pubmed

Dynamics of RIF1 SUMOylation is regulated by PIAS4 in the maintenance of Genomic Stability.

RIF1 TP53BP1

7.17e-054121229234018
Pubmed

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1.

RIF1 TP53BP1

7.17e-054121227494840
Pubmed

A genome wide association study of fast beta EEG in families of European ancestry.

ZEB2 CTBP2

7.17e-054121228040410
Pubmed

Mammalian Rif1 contributes to replication stress survival and homology-directed repair.

RIF1 TP53BP1

7.17e-054121219948482
Pubmed

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.

ZEB2 ELF3

7.17e-054121228247944
Pubmed

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts.

RIF1 TP53BP1

7.17e-054121227820601
Pubmed

Interaction between CASP8AP2 and ZEB2-CtBP2 Regulates the Expression of LEF1.

ZEB2 CTBP2

7.17e-054121235139734
Pubmed

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

RIF1 TP53BP1

7.17e-054121229160738
Pubmed

Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.

EPS15L1 AGFG2

7.17e-05412129446614
Pubmed

A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.

RIF1 TP53BP1

7.17e-054121223333306
Pubmed

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

RIF1 TP53BP1

7.17e-054121223727112
Pubmed

The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.

EPS15L1 AGFG2

7.17e-054121210613896
Pubmed

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.

RIF1 TP53BP1

7.17e-054121223306439
Pubmed

Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.

ERBB2 FASN

7.17e-054121217631500
Pubmed

A census of human transcription factors: function, expression and evolution.

CUX2 PBX4 RELB GATA5 RFX2 ATF6B ZEB2 CREB3L1 PLAGL1 ELF3 FOXE3 TBX2

8.08e-059081211219274049
Pubmed

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

CUX2 ADARB1 DLGAP3

8.93e-0525121328288114
Pubmed

FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells.

RIF1 TP53BP1

1.19e-045121229789392
Pubmed

Midline craniofacial malformations with a lipomatous cephalocele are associated with insufficient closure of the neural tube in the tuft mouse.

TET1 CDH2

1.19e-045121224931720
Pubmed

TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.

RELB CD40

1.19e-045121224324158
Pubmed

Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.

FAM220A PTPN2

1.19e-045121226026268
Pubmed

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer.

RIF1 TP53BP1

1.19e-045121238244928
Pubmed

Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap".

CHD7 FANCA

1.19e-045121220425471
Pubmed

A Systematic Approach to Defining the microRNA Landscape in Metastasis.

ZEB2 CDH2

1.19e-045121226069251
Pubmed

DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.

RIF1 TP53BP1

1.19e-045121229311308
Pubmed

ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice.

RIF1 TP53BP1

1.19e-045121229203878
Pubmed

Investigating the role of ankyrin-rich membrane spanning protein in human immunodeficiency virus type-1 Tat-induced microglia activation.

RELB CD40

1.19e-045121225636783
Pubmed

Human transcription factor protein interaction networks.

KMT2B RELB CHD7 ZNF318 MBD6 WASHC2A ZEB2 RIF1 ARID1B SUGP2 ANKRD17 ELF3 CTBP2 TP53BP1 DCP1A

1.36e-0414291211535140242
Pubmed

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

GGT2P CD40 CDH2

1.40e-0429121322424930
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

NRDC CAPN2 SCAMP3 NEDD1 DNAJC6 DNAAF5 PTPN2 DLGAP3 FASN MTMR14 ANKRD17 NID1

1.56e-049741211228675297
Pubmed

A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.

EPS15L1 AGFG2

1.78e-04612127568168
Pubmed

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.

CDH2 FOXE3

1.78e-046121217064680
Pubmed

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.

ARG1 CD40

1.78e-046121227622331
Pubmed

The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins.

ERBB2 GRIN2C

1.78e-046121211278603
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

SALL3 ZEB2 CTBP2

1.89e-0432121316516881
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

NRDC RIF1 ANKRD17 ULK1 TP53BP1

2.03e-04153121526365490
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A SGIP1 MAP1A DNAJC6 EPS15L1 SHANK2 FBXO41

2.21e-04347121717114649
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

KMT2B CHD7 MBD6 ARID1B CTBP2

2.29e-04157121530186101
Pubmed

Functional proteomics mapping of a human signaling pathway.

CNKSR1 KMT2B MAN2B1 ZEB2 ARID1B NID1 PLAGL1 CTBP2 DCP1A

2.33e-04591121915231748
Pubmed

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

RIF1 TP53BP1

2.49e-047121226308889
Pubmed

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.

KMT2B TP53BP1

2.49e-047121219433796
Pubmed

Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.

DLGAP3 SHANK2

2.49e-047121210527873
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CACNA1A MAN2B1 SLC44A2 BRME1 PBX4 DENND1C RFX2 RNF126 EPS15L1 SUGP2 IFI30

9.12e-0679712111chr19p13
GeneFamilyWASH complex

WASHC2C WASHC2A

3.39e-0468721331
GeneFamilyEF-hand domain containing

CAPN2 DNAH7 CAPN11 RASGRP1 EPS15L1 RAB11FIP3

6.58e-04219876863
GeneFamilyZinc fingers CXXC-type

KMT2B TET1

1.46e-0312872136
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT2P GGTLC3

1.72e-0313872564
GeneFamilyC2 domain containing|Calpains

CAPN2 CAPN11

2.31e-0315872975
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN

DENND1C MBD6 RNF126 ATF6B DLGAP3 TET1 DCP1A

3.66e-061391207M8948
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_DN

RELB ADARB1 ZEB2 IFNGR2 PTPN2 RASGRP1 PLAGL1 HERPUD1

3.75e-061981208M9407
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 PTPN2 KIF17 HERPUD1

4.62e-081871218bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-pDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17 HERPUD1

5.44e-081911218faf4de97003a938a243b0101456913c2b0e1804f
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 PTPN2 KIF17 HERPUD1

5.90e-0819312182c35aadc397e7e365c3daf8017ae1d3bd045f305
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A PTCRA CLIC3 RELB RNF126 PTPN2 HERPUD1

3.21e-0716312173087224d3f16f5d3aecc3e1e4366220231afe31f
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

CUX2 MAP1A PTCRA CLIC3 SLC44A2 PLAGL1 KIF17

3.35e-07164121706db4cc064f0765c481ce880207823872c27bfa9
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

3.64e-0716612179fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CUX2 MAP1A PTCRA CLIC3 SLC44A2 KIF17 TP53BP1

3.94e-0716812174bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

MAG MAP1A PTCRA CLIC3 SLC44A2 PCDH9 HERPUD1

6.51e-0718112172caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

MAG MAP1A PTCRA CLIC3 SLC44A2 PCDH9 HERPUD1

6.51e-071811217277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

DZIP1 ZEB2 SUGP2 NID1 PLAGL1 PROS1 TBX2

8.71e-0718912170c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell10x3'2.3-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17

9.02e-0719012171687e133a88c3d036a33a4f8aeefe320a4f02c39
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17

9.02e-0719012173cfc2646ba25b4bd8bb443cc1f46e18a270a1969
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

9.02e-071901217d06800ec9f6065c1cc536ed99e8569732272a94f
ToppCell10x5'v1-week_14-16-Myeloid_DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

9.02e-071901217485073e831afebdb393c7f4b622504d43d1b778b
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.00e-061931217bdbbfcbe339f23a88dfcc59d53c034bac1605b07
ToppCell10x5'v1-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.00e-061931217acafe177cd05b2966f5fa26ea02f420f13f2cee5
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-pDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAG CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.00e-0619312172a48e72f3df2ad64e1680fca759be8fd2190771e
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

SGIP1 DZIP1 ZEB2 PDE8B NID1 PLAGL1 CDH2

1.27e-062001217bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A GPR135 ZNF318 CFAP65 NOXO1 WNK4

6.24e-061661216eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A SGIP1 MAP1A ZEB2 GGTLC3 NID1

6.46e-061671216e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A SGIP1 MAP1A ZEB2 GGTLC3 NID1

6.46e-0616712167cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A SGIP1 MAP1A ZEB2 GGTLC3 NID1

6.46e-061671216bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CUX2 MAN2B1 MAP1A PTCRA CLIC3 HERPUD1

6.68e-06168121659b698f58cb206f0f8f0e8ad72b445d14ba24728
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|metastatic_Brain / Location, Cell class and cell subclass

CUX2 CLIC3 STIL CARD8 PTPN2 PCDH9

6.91e-06169121671f6761b9927f352e0ccc221ca373319915f4184
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MAP1A PTCRA CLIC3 SLC44A2 ZNF469 TP53BP1

7.39e-061711216f3bf5805823d5733b58742172e7668725ce82931
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17

7.39e-06171121672c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellIIF-Myeloid-pDC|IIF / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17

8.43e-06175121635cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1A PSD CLIC3 RELB NOXO1 CD40

8.43e-0617512161b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SGIP1 MAP1A DZIP1 DNAAF5 NOTUM PCDH9

8.43e-0617512161d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A DZIP1 PDE8B NID1 KIF17 PCDH9

8.43e-06175121612f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SGIP1 MAP1A DZIP1 DNAAF5 NOTUM PCDH9

8.43e-061751216427a7ee92fe16a90625946492062d37aa0f7235b
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 CAPN2 ZEB2 IFNGR2 CD40 IFI30

8.71e-061761216eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCellControl-Lymphoid-pDC|Control / Condition, Lineage and Cell class

CUX2 MAP1A PTCRA CLIC3 KIF17 PCDH9

8.71e-0617612165de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell390C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MAP1A PTCRA CLIC3 STIL ULK1 KIF17

8.71e-061761216aab9603b7943b7f7243eb6190ebba998566196f3
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAG MAP1A PTCRA CLIC3 KIF17 HERPUD1

9.00e-061771216e36c2005be74ee8ff03c2052504cb496faf86009
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

MAG CUX2 MAP1A PTCRA CLIC3 PCDH9

1.02e-0518112163d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.05e-05182121602e04294fce12591c32d7bd0e866a000ad1f836e
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.09e-0518312162c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

FHOD3 CREB3L1 ZNF469 NOTUM CDH2 TBX2

1.09e-051831216d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellURO-Myeloid-pDC|URO / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.12e-0518412160edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCellBac-SEP-Myeloid-pDC|Bac-SEP / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.16e-0518512163de50b2042f22b0fb62ff12c76d85cc67649a0bd
ToppCellICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.16e-0518512167564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.19e-051861216330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCelltumor_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CUX2 MAP1A PTCRA CLIC3 PCDH9 HERPUD1

1.19e-0518612163d7c1a281fb82db4471283f39937007d889a5f38
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.23e-051871216068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PSD DZIP1 CREB3L1 NOTUM SUSD2 CDH2

1.27e-051881216116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAG MAN2B1 PTCRA CLIC3 KIF17 HERPUD1

1.27e-0518812166b0e0192519ea3ca49fb21de3da9a0a108fcb64d
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

DZIP1 ADARB1 ZEB2 CD40 NID1 TBX2

1.27e-0518812163f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell10x5'v1-week_12-13-Myeloid_DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAG MAN2B1 PTCRA CLIC3 KIF17 HERPUD1

1.27e-0518812160b19c35fdc2b9e064e8f03ef69ae08644794ec24
ToppCellMesenchymal_cells-Osteoblasts|World / Lineage and Cell class

FHOD3 CREB3L1 ZNF469 NOTUM CDH2 TBX2

1.27e-05188121689f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SGIP1 ZEB2 NID1 PLAGL1 CDH2 TBX2

1.35e-0519012162ab604d35456beba71c25511e0f819000e6642d2
ToppCelllymphoid-B_cell-Naive_B_cell|lymphoid / Lineage, cell class and subclass

ZEB2 IFNGR2 CD40 SKAP2 PCDH9 HERPUD1

1.35e-051901216b8b05894e811e431d797ac4fa3ccff4963a154e7
ToppCelllymphoid-B_cell|lymphoid / Lineage, cell class and subclass

ZEB2 IFNGR2 CD40 SKAP2 PCDH9 HERPUD1

1.35e-051901216c451de643ee08c2ff1093e807c65d724237473c5
ToppCell(011)_pDC|World / immune cells in Peripheral Blood (logTPM normalization)

CUX2 MAP1A PTCRA KIF26B CLIC3 KIF17

1.39e-051911216d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.39e-0519112168c487704cbbb5eeff54e8c6fb6fffa1472b5351f
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.39e-051911216989bf108c7f2c78dd7f14481570f1819673a5469
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.39e-05191121678d523f562d32fc408a20d99b0c61cc103241bc0
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.39e-0519112163e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.39e-051911216bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellCOVID-19-Lymphoid-pDC|COVID-19 / Condition, Lineage and Cell class

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.39e-05191121625343b11d42128ad16659e5519cd1673266cc505
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SGIP1 ZEB2 PDE8B NID1 CDH2 TBX2

1.39e-0519112162ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.43e-051921216d9ff2293358c8b031ba212021012e058014ff472
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.43e-051921216f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.43e-0519212162e8611d65090e39f1a6e74c972288e7b68376d15
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A PTCRA CLIC3 SLC44A2 HERPUD1

1.43e-05192121643569726df281eebe57499e0993b9fd9d36118c2
ToppCell10x3'2.3-week_14-16-Myeloid_DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG PTCRA CLIC3 PTPN2 KIF17 HERPUD1

1.47e-051931216c6633aca0eb4d699c4d3da3199b84bebd87e2d31
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAG PTCRA CLIC3 PTPN2 KIF17 HERPUD1

1.47e-051931216a32791b4bdb7c5f2b4cc75b660321ab75c4fac9b
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.51e-05194121674545942aded51a0f4ee96054b4ce12c4d99a8a0
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

CUX2 MAP1A PTCRA CLIC3 KIF17 PCDH9

1.51e-0519412165f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

CUX2 MAP1A PTCRA CLIC3 KIF17 HERPUD1

1.51e-051941216c25fc353001cdf9fcd772da5a254c857e555eab8
ToppCellAT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CLIC3 CREB3L1 FASN SUSD2 PLAGL1 PCDH9

1.56e-051951216bb45a17871a8a2593bc16a95f22e3c239c49985b
ToppCellControl-B_naive-8|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADARB1 ZEB2 RASGRP1 ARID1B PCDH9 HERPUD1

1.61e-05196121654074da84000e4749ade8acc542f05a275bf829f
ToppCell10x5'-Liver-Lymphocytic_NK-NK_CD16|Liver / Manually curated celltypes from each tissue

ERBB2 CLIC3 SLC44A2 ZEB2 MEX3C CTBP2

1.61e-051961216e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCelldistal-1-Hematologic-Plasmacytoid_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAG CUX2 MAP1A PTCRA CLIC3 ZNF469

1.65e-051971216166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRIN2C DNAJC6 ZEB2 PRSS42P CDH2 PCDH9

1.65e-0519712165c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRIN2C DNAJC6 ZEB2 PRSS42P CDH2 PCDH9

1.65e-051971216c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

CUX2 MAP1A PTCRA CLIC3 SLC44A2 ULK1

1.70e-051981216fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

CUX2 MAP1A PTCRA PBX4 RNF126 HERPUD1

1.70e-051981216d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NEB ZEB2 RASGRP1 SKAP2 PCDH9 SERTAD3

1.70e-051981216dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHOD3 GATA5 ADARB1 NID1 PCDH9 TBX2

1.70e-051981216c12e7511628db819a52959bb68580e27c00c2e41
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZEB2 MEX3C PTPN2 ARID1B PCDH9 HERPUD1

1.75e-051991216dd94e42b62af7cbd69c472681d3c758552694ae2
ToppCellmLN-(5)_Dendritic_cell-(54)_pDC|mLN / shred on region, Cell_type, and subtype

CUX2 MAP1A PTCRA CLIC3 ULK1 KIF17

1.75e-0519912161e738219784a446ee8b0ddeb408e0050e1929e60
ToppCellmLN-Dendritic_cell-pDC|mLN / Region, Cell class and subclass

CUX2 MAP1A PTCRA CLIC3 ULK1 KIF17

1.75e-05199121654f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCelldistal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLIC3 CREB3L1 FASN SUSD2 ELF3 PCDH9

1.80e-052001216a77087a393aad674d4aa457ca6c0077b0424053d
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLIC3 CREB3L1 FASN SUSD2 ELF3 PCDH9

1.80e-052001216f47bb79202a59404e4916993a1f59cffcf710320
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SGIP1 DZIP1 ZEB2 PDE8B NID1 PLAGL1

1.80e-052001216d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLIC3 CREB3L1 FASN SUSD2 ELF3 PCDH9

1.80e-052001216b0e5c8b425f47833cdc00b5aa3734c8c980f0967
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLIC3 CREB3L1 FASN SUSD2 ELF3 PCDH9

1.80e-052001216bcaab6cb7f165dfcf3fb499497b361b062f9dbff
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm|5w / Sample Type, Dataset, Time_group, and Cell type.

RFX2 ARHGAP4 NOXO1 CD40 PCIF1 ULK1

1.80e-0520012160927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CHD7 ZNF318 ADARB1 ARID1B CD40 PCDH9

1.80e-052001216222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell(54)_pDC|World / shred on Cell_type and subtype

CUX2 MAP1A PTCRA CLIC3 ULK1 KIF17

1.96e-052031216b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1A CUX2 PTCRA PLAGL1 TREML1

3.52e-051361215a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 IGDCC3 CFAP65 DLGAP3 CDH2

3.64e-0513712154dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 IGDCC3 CFAP65 DLGAP3 CDH2

3.64e-051371215c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellMild/Remission-B_intermediate-14|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GRIN2C DNAH7 ZEB2 DLGAP3 PLAGL1

4.18e-05141121569e32125a0e8f0c8561e5e7a93607f368f09546f
ToppCellInt-URO-Other|Int-URO / Disease, Lineage and Cell Type

MAP1A PTCRA CLIC3 KIF17 HERPUD1

5.79e-051511215ea5f25842e621be41a6491c9959d419d9cc7ebd6
ToppCellInt-URO-Other-RBC|Int-URO / Disease, Lineage and Cell Type

MAP1A PTCRA CLIC3 KIF17 HERPUD1

5.79e-0515112150344d482f1c55c9eaa15beb8d6bac1c6cdca21b3
ToppCellControl-Epithelial_airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP10B CFAP65 ARG1 IFI30 ELF3

7.18e-05158121535aee1c3b92169e73569331022833cb44ab7e7e8
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CUX2 MAP1A PTCRA CLIC3 HERPUD1

7.62e-05160121561f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CUX2 MAP1A PTCRA CLIC3 HERPUD1

7.62e-05160121534b4f710cfcb6ec370b8b074f3cbfe272f392cec
DiseaseC-reactive protein measurement

CUX2 SGIP1 MAP1A FAM220A PBX4 RELB CHD7 DNAJC6 ADARB1 CREB3L1 FANCA PTPN2 ZNF469 PCIF1 NID1 HERPUD1 AFF4 TP53BP1

1.66e-06120611918EFO_0004458
Diseasetriglycerides to total lipids in very large HDL percentage

CD40 PCIF1 HERPUD1 TP53BP1

1.17e-04621194EFO_0022339
Diseasehereditary spastic paraplegia 76 (implicated_via_orthology)

CAPN2 CAPN11

1.60e-0451192DOID:0110821 (implicated_via_orthology)
DiseaseBiliary Tract Neoplasm

ERBB2 ELF3

2.39e-0461192C0005426
Diseasecholesterol in large HDL measurement

CD40 PCIF1 HERPUD1 TP53BP1

3.14e-04801194EFO_0021900
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT2P GGTLC3

3.34e-0471192DOID:5022 (biomarker_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

PBX4 RELB PCIF1 HERPUD1 TP53BP1

3.99e-041531195EFO_0004611, EFO_0020946
Diseaseprotein FAM177A1 measurement

SLC44A2 HERPUD1

4.44e-0481192EFO_0801948
Diseasealcohol dependence (biomarker_via_orthology)

GGT2P GGTLC3

4.44e-0481192DOID:0050741 (biomarker_via_orthology)
Diseaselactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement

CHD7 HERPUD1

5.70e-0491192EFO_0800517
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

KMT2B IFNGR2 PTPN2 RASGRP1 CD40

6.44e-041701195EFO_0000685, EFO_0007791, EFO_0007837
Diseasefree cholesterol to total lipids in very small VLDL percentage

PCIF1 HERPUD1 TP53BP1

7.02e-04431193EFO_0022290
Diseaseselective IgA deficiency disease

CREB3L1 PTPN2 FASN

8.55e-04461193EFO_1001929
Diseasefamilial hyperlipidemia

SLC44A2 PBX4 RELB SUGP2

9.10e-041061194MONDO_0001336
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

PCIF1 HERPUD1 TP53BP1

1.16e-03511193EFO_0022302
Diseasealcohol use disorder (implicated_via_orthology)

ERBB2 PSD CLIC3 ARID1B CTBP2

1.19e-031951195DOID:1574 (implicated_via_orthology)
Diseaseskin melanoma (is_marker_for)

CD40 AFF4

1.22e-03131192DOID:8923 (is_marker_for)
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

IFNGR2 PTPN2 RASGRP1 FASN CD40 SKAP2

1.28e-032951196EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Diseasetriglycerides in HDL measurement

PCIF1 HERPUD1 TP53BP1

1.29e-03531193EFO_0022317
Diseasetriglycerides in medium HDL measurement

PCIF1 HERPUD1 TP53BP1

1.37e-03541193EFO_0022321
Diseasetriglycerides in very large HDL measurement

PBX4 HERPUD1 TP53BP1

1.44e-03551193EFO_0022324
Diseasecholesterol to total lipids in large HDL percentage

PCIF1 HERPUD1 TP53BP1

1.44e-03551193EFO_0022234
Diseasesystemic lupus erythematosus

ERBB2 SLC44A2 ARHGAP4 PTPN2 RASGRP1 EPS15L1 CD40 ELF3 SKAP2 CDH2

1.50e-0379911910MONDO_0007915
Diseasetriglycerides to total lipids in medium HDL percentage

PCIF1 HERPUD1 TP53BP1

1.52e-03561193EFO_0022333
Diseasefree cholesterol to total lipids in medium VLDL percentage

PCIF1 HERPUD1 TP53BP1

1.60e-03571193EFO_0022284
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

PCIF1 HERPUD1

1.64e-03151192EFO_0022328
Diseasepre-eclampsia (is_marker_for)

ERBB2 PTPN2 CD40

1.68e-03581193DOID:10591 (is_marker_for)
Diseasecholesteryl esters to total lipids in large HDL percentage

PCIF1 HERPUD1 TP53BP1

1.76e-03591193EFO_0022248
Diseasetriglycerides to total lipids in large HDL percentage

PCIF1 HERPUD1 TP53BP1

1.85e-03601193EFO_0022330
Diseasecholesterol to total lipids in medium HDL percentage

PCIF1 HERPUD1 TP53BP1

1.85e-03601193EFO_0022237
Diseaselevel of Sterol ester (27:1/18:1) in blood serum

RELB ANKRD17

1.87e-03161192OBA_2045195
Diseasecathepsin L1 measurement

MAN2B1 IFI30

1.87e-03161192EFO_0010619
Diseasetriglycerides in small VLDL measurement

PCIF1 HERPUD1 TP53BP1

1.94e-03611193EFO_0022145
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

PCIF1 HERPUD1 TP53BP1

1.94e-03611193EFO_0008317, EFO_0008596, EFO_0020946
Diseasetriglycerides in small HDL measurement

PCIF1 HERPUD1 TP53BP1

2.03e-03621193EFO_0022158
Diseasephospholipids in large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.03e-03621193EFO_0022169
Diseasetotal lipids in very large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.03e-03621193EFO_0022313
Diseasephospholipids in very large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.03e-03621193EFO_0022299
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

PCIF1 HERPUD1

2.11e-03171192EFO_0022232
Diseasefree cholesterol to total lipids in medium LDL percentage

PCIF1 HERPUD1 TP53BP1

2.13e-03631193EFO_0022283
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

MAP1A RELB PCIF1 HERPUD1 TP53BP1

2.18e-032241195EFO_0004574, EFO_0008317
Diseasecholesterol in large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.33e-03651193EFO_0021902
Diseasecholesterol in very large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.33e-03651193EFO_0022230
Diseaseinflammatory bowel disease

SCAMP3 IFNGR2 PTPN2 RASGRP1 DLGAP3 CD40 SKAP2

2.34e-034491197EFO_0003767
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

PBX4 HERPUD1

2.37e-03181192EFO_0008317, EFO_0008589
Diseasestem Cell Factor measurement

CD40 PCIF1 HERPUD1

2.54e-03671193EFO_0008291
Diseasetotal lipids in small VLDL

PCIF1 HERPUD1 TP53BP1

2.54e-03671193EFO_0022148
Diseasetotal lipids in large VLDL

PCIF1 HERPUD1 TP53BP1

2.54e-03671193EFO_0022175
Diseasehearing loss

TRIOBP ZNF318 CTBP2

2.54e-03671193EFO_0004238
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

PCIF1 HERPUD1

2.64e-03191192EFO_0004612, EFO_0008589
Diseasetriglycerides in very small VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.65e-03681193EFO_0022144
Diseasetriglycerides to phosphoglycerides ratio

PCIF1 HERPUD1 TP53BP1

2.65e-03681193EFO_0022327
Diseasefree cholesterol in large VLDL measurement

PCIF1 HERPUD1 TP53BP1

2.65e-03681193EFO_0022265
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

RELB PCIF1 HERPUD1 TP53BP1

2.80e-031441194EFO_0004611, EFO_0020943
Diseasetriglycerides to total lipids in small HDL percentage

PCIF1 HERPUD1 TP53BP1

3.11e-03721193EFO_0022336
Diseasefree cholesterol to total lipids in chylomicrons and extremely large VLDL percentage

PCIF1 HERPUD1

3.22e-03211192EFO_0022277
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

PCIF1 HERPUD1

3.22e-03211192EFO_0022246
Diseasenose morphology measurement, mouth morphology measurement

CD40 GDPGP1

3.22e-03211192EFO_0007843, EFO_0007955
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

RELB PCIF1 HERPUD1 TP53BP1

3.24e-031501194EFO_0004611, EFO_0020947
Diseasetotal lipids in large HDL

CD40 PCIF1 HERPUD1

3.37e-03741193EFO_0022189
Diseaseautism spectrum disorder (implicated_via_orthology)

SCAMP3 CHD7 ARID1B SHANK2

3.40e-031521194DOID:0060041 (implicated_via_orthology)
DiseaseImmunologic Deficiency Syndromes

CHD7 RASGRP1

3.86e-03231192C0021051
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

PCIF1 HERPUD1 TP53BP1

3.90e-03781193EFO_0022187

Protein segments in the cluster

PeptideGeneStartEntry
SFGSAPAQLPPAFVD

nan

41

Q6ZRM9
FDEGTPPTNFDTFPA

CACNA1A

641

O00555
FDGDPASNTAPLQPE

ERBB2

381

P04626
QLGSADFPEAPDPFQ

EPS15L1

801

Q9UBC2
EPFPADRLFPGSSFL

CREB3L1

6

Q96BA8
EPFSFAQGPLKDAPN

CTBP2

301

P56545
FLEETLGPPDFPSLA

CLIC3

81

O95833
SFQDDPPSAFPKGLG

FAM220A

166

Q7Z4H9
DLLHAPEEGPFTFPN

RASGRP1

621

O95267
PGPFDQGSPFAQELL

ELF3

156

P78545
DANPGPQTESSKFPF

ARID1B

1961

Q8NFD5
IAPNFSAPLPFGPFS

ANKRD17

2241

O75179
SAPLPFGPFSTLFEN

ANKRD17

2246

O75179
EDPLFPAEPSSLGFK

CAPN11

81

Q9UMQ6
SLDDRLQPPSFDPSG

CUX2

111

O14529
FFEAACPASLQEDPP

DENND1C

16

Q8IV53
PGDASQKEPNSFLPF

DCP1A

246

Q9NPI6
SFLPFPFEQLGGAPQ

DCP1A

256

Q9NPI6
AATAPAGLPSNPLAF

CHD7

2876

Q9P2D1
AGLPSNPLAFNPFLL

CHD7

2881

Q9P2D1
PPFDVPDANGSFLPS

ATP10B

346

O94823
IQQGEDAFPPSSPLF

AFF4

21

Q9UHB7
GDLPFADIPNDSPFQ

ARG1

51

P05089
FSPFPAPTAGELALE

RAB11FIP3

161

O75154
PPSALLPDPDFFSGT

RELB

456

Q01201
PDFGVPESPASFLNF

PTPN2

181

P17706
TFFASLLPEGPPAIA

HERPUD1

376

Q15011
EAFPFPSPEQGLALS

MBD6

516

Q96DN6
SSSLGAFFAGDLPPP

PTCRA

261

Q6ISU1
ELEQLFPPASAAGQP

IGDCC3

716

Q8IVU1
AGPFEASQPADSAVP

MAP1A

781

P78559
SAFGFSSLQPAPPQL

MAP1A

2166

P78559
PSFSAGDNPPVLFSS

MAG

546

P20916
LSSPGLPAAFASFPA

MAIP1

76

Q8WWC4
LGPPPAASNSSDLFD

CLINT1

411

Q14677
DGFDFLPQLNSVFPP

NEDD1

431

Q8NHV4
SLPFSFPDELPNSCL

MTMR14

576

Q8NCE2
LDFNFGAAPFKAPPS

CFAP65

1171

Q6ZU64
EPSSFPFEELPAQFG

KIF26B

941

Q2KJY2
PTFNAPAALFGEAAP

CCDC120

11

Q96HB5
TFPLDPALDSDVGPN

PCDHGB2

151

Q9Y5G2
FPIPSATDPDTGFNG

PCDH9

161

Q9HC56
PAAPLPGLFVQTDAA

PDE8B

36

O95263
LFPPTFGAVAPFLAD

NID1

96

P14543
PDALPQSPFDAALCS

GDPGP1

51

Q6ZNW5
LDKDALAPGPFASFP

KMT2B

1141

Q9UMN6
PFSCEDLSSLGPAPA

NLRX1

196

Q86UT6
LFNGFETPDKAEPPF

ADARB1

176

P78563
SVAPAAAPTPGEQFL

INSM2

151

Q96T92
ALPAFTNEFGAPPSP

GGTLC3

81

B5MD39
AAPAAGQPVESFPLD

NOTUM

41

Q6P988
SGPFPLPSAGDAFLT

PBX4

311

Q9BYU1
PEDFAFPSTAPSPQA

GATA5

366

Q9BWX5
FLDLFTPPGGSAPAA

GPR135

161

Q8IZ08
DASDFEAPPEQLFPS

BRME1

546

Q0VDD7
LDFAPLSGSFEANPP

PCIF1

541

Q9H4Z3
ASPLQALDFFGNGPP

IFI30

26

P13284
FASDFLSPEAASPAP

FANCA

1206

O15360
PTAFPVPTFQDLAGF

DLGAP3

861

O95886
EPPPFDLAKAFGDSN

DNAH7

3411

Q8WXX0
LDDTDPFNSTNFPEP

FHOD3

11

Q2V2M9
FDPFGAPSKPSGQDL

DNAJC6

581

O75061
DLQLVAASAPPPFSG

CARD8

436

Q9Y2G2
AAAAAASGFPLAPEP

FBXO41

56

Q8TF61
PPELLFSASLPALGF

MAN2B1

561

O00754
FAAAAAAPPDPLSQL

IFNGR2

16

P38484
KPDDLPAFPLFSAFG

SLC44A2

481

Q8IWA5
GLDLGTFPNPFPTNE

C2orf66

71

Q6UXQ4
EKLPSLFNPGNPDAF

COG2

326

Q14746
ALEEPGPAADPTAFQ

DNAAF5

56

Q86Y56
SGIDANPNALFPPVE

FASN

806

P49327
EAGTLFQDPSFPAIP

CAPN2

41

P17655
FQDPSFPAIPSALGF

CAPN2

46

P17655
FAEPSELDNPFQDPA

SCAMP3

11

O14828
ELPSQLFDPNFALGP

SALL3

1031

Q9BXA9
LFDPNFALGPSQSTP

SALL3

1036

Q9BXA9
DPNAGPFAFDLPLSP

CDH2

631

P19022
FPLALQESPGAAAEP

HS3ST4

61

Q9Y661
LPAFTNEFGAPPSPA

GGT2P

426

P36268
NPGAADEPPKQFTFD

KIF17

41

Q9P2E2
APGPPSDTFVFNLAL

RXFP4

71

Q8TDU9
PPGTSPQELFLFGAN

SUSD2

616

Q9UGT4
AAALPPFPLGASAQN

PLAGL1

236

Q9UM63
LEALASPGPTQSPFF

PSD

426

A5PKW4
SASGPNAPPALFELC

LRRC41

36

Q15345
FPSAASFPLTAAAPG

NKX1-2

276

Q9UD57
SHVFPEFPAPDLGSF

RFX2

341

P48378
SDGAQFPPIAAQDLP

SKAP2

101

O75563
KFDGSENRPFSPSPL

RIF1

1226

Q5UIP0
AAFSGFPALPAVAPS

FOXE3

11

Q13461
TPFEPVNPLSGFGSD

MEX3C

511

Q5U5Q3
IFDDSFEIPTFPPGA

RNF126

86

Q9BV68
PVFSIQDSPFGDAPL

PROSER3

6

Q2NL68
ASPPAFQVGSPEALA

PROSER3

366

Q2NL68
NSPGPTLDFTFRADP

SELENOV

201

P59797
TGFFAPQPLDLEPAL

NOXO1

121

Q8NFA2
GLPDVPFSATPVNAF

PROS1

621

P07225
APPSAASGPLPFFQF

DZIP1

46

Q86YF9
QFDPFPFLPDTSDAE

TRIOBP

1081

Q9H2D6
APEPSLFFQDPPGTS

TRIOBP

1181

Q9H2D6
PLFPPDLFGELLASS

ARHGAP4

591

P98171
FLPPPESFDAVADSG

SHANK2

1476

Q9UPX8
ALPPEPLFLGEEDFS

SERTAD3

76

Q9UJW9
SFLPANTQGFPLAPE

TET1

506

Q8NFU7
GAFASSFPAPLFPPQ

AGFG2

411

O95081
FIAFNFGPVSISEPP

ATF6B

406

Q99941
DVFAFDLSSNPSPGP

CNKSR1

321

Q969H4
FLPESFCGSPLPSEQ

NDUFV1-DT

161

Q8NBR9
PDVPVFFPSGQLAES

STIL

881

Q15468
FSPAPDNFDQEPILD

EEFSEC

351

P57772
FEAPPLQGQAAAPAS

TRIM55

511

Q9BYV6
FDAQILPGAQPPFDA

NUFIP1

81

Q9UHK0
AAAQPSFFPALALPP

TBX2

31

Q13207
ALAPLFGPPLESAFD

SGIP1

196

Q9BQI5
AVGLQDIAPSPAAFP

SUGP2

501

Q8IX01
DIAPSPAAFPNFEDS

SUGP2

506

Q8IX01
PNFGHLTDPFDTPAF

NRDC

411

O43847
AGPPLNLFTSFPGDS

PRSS42P

56

Q7Z5A4
FAPPKLTDEDFSPFG

WASHC2C

341

Q9Y4E1
DSPEIPFQAAAGPSD

TP53BP1

1461

Q12888
EESQLPGPLGPSAFF

ZNF469

621

Q96JG9
FAPPKLTDEDFSPFG

WASHC2A

341

Q641Q2
ENDLPPGTPDAFAQL

ZEB2

196

O60315
AFSDPAGSANPLEPS

TREML1

141

Q86YW5
DFEPIPSFSGFPLDS

ZNF318

2061

Q5VUA4
PPEVFPALDSAELGF

UBQLN3

576

Q9H347
PALDSAELGFLSPPF

UBQLN3

581

Q9H347
SSGFLDASDPALQPP

WNK4

591

Q96J92
PAQFPGDLVAEAPSA

ULK1

361

O75385
INFPDDLPGSNTAAP

CD40

236

P25942
AQFTPLADPPDIEFA

NEB

251

P20929
NLALGSTDAPPATFP

GRIN2C

256

Q14957