Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	MAML1 NSD1 N4BP2L2 NCOA6 PAWR KMT2D RUNX1T1 ARID1A	7.04e-06	562	37	8	GO:0003712
GeneOntologyMolecularFunction	retinoic acid-responsive element binding	ZNF536 NR2F1	6.97e-05	7	37	2	GO:0044323
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	MAML1 NSD1 N4BP2L2 NCOA6 PAWR IRS2 KMT2D RUNX1T1 ARID1A	2.07e-04	1160	37	9	GO:0030674
GeneOntologyMolecularFunction	molecular adaptor activity	MAML1 NSD1 N4BP2L2 NCOA6 PAWR IRS2 KMT2D RUNX1T1 ARID1A	6.55e-04	1356	37	9	GO:0060090
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	NSD1 NCOA6	8.25e-04	23	37	2	GO:0046965
GeneOntologyMolecularFunction	transcription corepressor activity	NSD1 N4BP2L2 PAWR RUNX1T1	8.27e-04	229	37	4	GO:0003714
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ONECUT2 KLF17 ZNF536 KMT2D ZNF226 NR1D1 MTF1 MYRF NR2F1	8.77e-04	1412	37	9	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NSD1 ONECUT2 KLF17 ZNF536 ZNF226 NR1D1 MTF1 NR2F1	1.69e-03	1244	37	8	GO:0000978
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NSD1 NCOA6	1.81e-03	34	37	2	GO:0046966
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	NSD1 ONECUT2 KLF17 ZNF536 ZNF226 NR1D1 MTF1 NR2F1	1.94e-03	1271	37	8	GO:0000987
GeneOntologyMolecularFunction	transcription coactivator activity	MAML1 NCOA6 KMT2D ARID1A	2.31e-03	303	37	4	GO:0003713
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	KLF17 ZNF536 NR1D1 NR2F1	2.82e-03	320	37	4	GO:0001227
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	NSD1 KMT2D	3.01e-03	44	37	2	GO:0140938
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	KLF17 ZNF536 NR1D1 NR2F1	3.01e-03	326	37	4	GO:0001217
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	NSD1 NCOA6	4.34e-03	53	37	2	GO:0030331
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NSD1 ONECUT2 KLF17 ZNF536 ZNF226 NR1D1 MTF1 NR2F1	4.56e-03	1459	37	8	GO:0000977
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	NSD1 NCOA6	4.66e-03	55	37	2	GO:0042974
GeneOntologyMolecularFunction	nuclear receptor binding	NSD1 NCOA6 ARID1A	4.97e-03	187	37	3	GO:0016922
GeneOntologyMolecularFunction	nuclear receptor activity	NR1D1 NR2F1	5.53e-03	60	37	2	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR1D1 NR2F1	5.71e-03	61	37	2	GO:0098531
GeneOntologyCellularComponent	MLL3/4 complex	NCOA6 KMT2D	1.99e-04	12	37	2	GO:0044666
GeneOntologyCellularComponent	histone methyltransferase complex	NSD1 NCOA6 KMT2D	3.16e-04	75	37	3	GO:0035097
GeneOntologyCellularComponent	nuclear protein-containing complex	PCF11 NSD1 NCOA6 KMT2D PYGO2 ARID1A POM121C INO80D NABP2	5.26e-04	1377	37	9	GO:0140513
GeneOntologyCellularComponent	methyltransferase complex	NSD1 NCOA6 KMT2D	9.17e-04	108	37	3	GO:0034708
HumanPheno	Scimitar anomaly	KMT2D MYRF	2.54e-05	4	11	2	HP:0011626
Domain	PHD	NSD1 DIDO1 KMT2D PYGO2	1.28e-05	75	36	4	PF00628
Domain	Znf_PHD-finger	NSD1 DIDO1 KMT2D PYGO2	1.58e-05	79	36	4	IPR019787
Domain	PHD	NSD1 DIDO1 KMT2D PYGO2	2.53e-05	89	36	4	SM00249
Domain	Znf_PHD	NSD1 DIDO1 KMT2D PYGO2	2.76e-05	91	36	4	IPR001965
Domain	ZF_PHD_2	NSD1 DIDO1 KMT2D PYGO2	3.27e-05	95	36	4	PS50016
Domain	ZF_PHD_1	NSD1 DIDO1 KMT2D PYGO2	3.40e-05	96	36	4	PS01359
Domain	Znf_FYVE_PHD	NSD1 DIDO1 KMT2D PYGO2	1.78e-04	147	36	4	IPR011011
Domain	Zinc_finger_PHD-type_CS	NSD1 DIDO1 PYGO2	2.65e-04	65	36	3	IPR019786
Domain	Post-SET_dom	NSD1 KMT2D	4.26e-04	16	36	2	IPR003616
Domain	PostSET	NSD1 KMT2D	4.26e-04	16	36	2	SM00508
Domain	POST_SET	NSD1 KMT2D	4.26e-04	16	36	2	PS50868
Domain	SET	NSD1 KMT2D	2.83e-03	41	36	2	PF00856
Domain	SET	NSD1 KMT2D	3.54e-03	46	36	2	SM00317
Domain	zf-C4	NR1D1 NR2F1	3.54e-03	46	36	2	PF00105
Domain	NUCLEAR_REC_DBD_1	NR1D1 NR2F1	3.54e-03	46	36	2	PS00031
Domain	Znf_hrmn_rcpt	NR1D1 NR2F1	3.54e-03	46	36	2	IPR001628
Domain	Nuclear_hrmn_rcpt	NR1D1 NR2F1	3.54e-03	46	36	2	IPR001723
Domain	ZnF_C4	NR1D1 NR2F1	3.54e-03	46	36	2	SM00399
Domain	NUCLEAR_REC_DBD_2	NR1D1 NR2F1	3.54e-03	46	36	2	PS51030
Domain	-	NR1D1 NR2F1	3.70e-03	47	36	2	1.10.565.10
Domain	HOLI	NR1D1 NR2F1	3.85e-03	48	36	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR1D1 NR2F1	3.85e-03	48	36	2	IPR000536
Domain	Hormone_recep	NR1D1 NR2F1	3.85e-03	48	36	2	PF00104
Domain	SET_dom	NSD1 KMT2D	4.18e-03	50	36	2	IPR001214
Domain	SET	NSD1 KMT2D	4.18e-03	50	36	2	PS50280
Domain	-	NR1D1 NR2F1	5.39e-03	57	36	2	3.30.50.10
Domain	Znf_NHR/GATA	NR1D1 NR2F1	5.58e-03	58	36	2	IPR013088
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	NCOA6 SEC24D ACACA MTF1	5.27e-06	55	30	4	M27001
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	PCF11 MAML1 KMT2D PSMD13 ZNF226 ARID1A POM121C NR1D1 NR2F1 NABP2	3.02e-05	1022	30	10	MM15436
Pathway	REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	NCOA6 ACACA MTF1	9.44e-05	42	30	3	M27172
Pathway	REACTOME_METABOLISM_OF_STEROIDS	NCOA6 SEC24D ACACA MTF1	3.01e-04	154	30	4	M27832
Pubmed	Interaction network of human early embryonic transcription factors.	MAML1 NCOA6 ZNF536 KMT2D PYGO2 ARID1A POM121C SOBP	2.97e-09	351	37	8	38297188
Pubmed	Human transcription factor protein interaction networks.	PCF11 MAML1 DIDO1 NCOA6 ZNF536 KMT2D PSMD13 PYGO2 ARID1A POM121C INO80D SOBP	1.58e-08	1429	37	12	35140242
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NSD1 NCOA6 ZNF536 KMT2D ARID1A	2.81e-08	83	37	5	28794006
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MAML1 NSD1 NCOA6 IRS2 KMT2D ACACA DNAJC14 ARID1A POM121C MYRF	1.61e-07	1105	37	10	35748872
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PCF11 MAML1 NCOA6 KMT2D PYGO2 ARID1A	3.77e-07	268	37	6	33640491
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PCF11 MAML1 NCOA6 KMT2D PYGO2 ARID1A POM121C	4.73e-07	457	37	7	32344865
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	DIDO1 KLF17 ZNF536 ZNF226 ARID1A NR1D1 MTF1 NR2F1	6.57e-07	709	37	8	22988430
Pubmed	Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.	KMT2D ARID1A	3.30e-06	3	37	2	27387124
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D PYGO2	3.30e-06	3	37	2	26902498
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MAML1 NCOA6 ZNF536 IRS2 KMT2D ARID1A POM121C	4.32e-06	638	37	7	31182584
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NSD1 ONECUT2 DIDO1 NCOA6 KMT2D ARID1A POM121C INO80D NR2F1	6.45e-06	1294	37	9	30804502
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2D ARID1A	6.60e-06	4	37	2	34645806
Pubmed	Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma.	KMT2D ARID1A	6.60e-06	4	37	2	26138514
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PCF11 DIDO1 NCOA6 IRS2 KMT2D ACACA NR1D1	1.51e-05	774	37	7	15302935
Pubmed	Congenital Diaphragmatic Hernia Overview	KMT2D ARID1A MYRF	1.63e-05	46	37	3	20301533
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	NCOA6 KMT2D	1.65e-05	6	37	2	17021013
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ONECUT2 DIDO1 KLF17 ARID1A NR1D1 MTF1 NR2F1	2.00e-05	808	37	7	20412781
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	NCOA6 KMT2D	2.30e-05	7	37	2	19556342
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NSD1 DIDO1 NCOA6 KMT2D ACACA ARID1A	2.31e-05	549	37	6	38280479
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DIDO1 NCOA6 KMT2D ARID1A POM121C	2.96e-05	341	37	5	32971831
Pubmed	Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.	NCOA6 KMT2D	3.07e-05	8	37	2	17178841
Pubmed	Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.	PCF11 NCOA6 ARID1A	3.46e-05	59	37	3	28813667
Pubmed	Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.	KMT2D PYGO2	4.93e-05	10	37	2	20937768
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	KMT2D ARID1A INO80D	5.53e-05	69	37	3	28481362
Pubmed	Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).	NR1D1 NR2F1	7.22e-05	12	37	2	16219912
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NCOA6 KMT2D ARID1A	7.98e-05	78	37	3	28611094
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	NCOA6 KMT2D	8.53e-05	13	37	2	17761849
Pubmed	Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.	NSD1 MTF1	8.53e-05	13	37	2	16093251
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	NCOA6 KMT2D	9.94e-05	14	37	2	12482968
Pubmed	The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.	NCOA6 KMT2D	1.15e-04	15	37	2	17925232
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	NCOA6 KMT2D	1.31e-04	16	37	2	24368734
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PCF11 MAML1 DIDO1 NCOA6 KMT2D ARID1A INO80D	1.42e-04	1103	37	7	34189442
Pubmed	MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.	NCOA6 KMT2D	1.48e-04	17	37	2	26180087
Pubmed	Integrator3, a partner of single-stranded DNA-binding protein 1, participates in the DNA damage response.	ACACA NABP2	1.48e-04	17	37	2	19759019
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	NCOA6 KMT2D	1.67e-04	18	37	2	17500065
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	NCOA6 KMT2D	2.07e-04	20	37	2	29785026
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	NCOA6 KMT2D	2.07e-04	20	37	2	19047629
Pubmed	FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells.	NCOA6 KMT2D	2.07e-04	20	37	2	32350066
Pubmed	A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.	NSD1 NR2F1	2.51e-04	22	37	2	23975195
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	NCOA6 KMT2D	2.51e-04	22	37	2	26886794
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	MAML1 ZNF536 POM121C	2.59e-04	116	37	3	30804394
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ONECUT2 KLF17 NR1D1 MTF1 NR2F1	2.65e-04	544	37	5	28473536
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NCOA6 ARID1A POM121C	3.07e-04	123	37	3	26912792
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	N4BP2L2 DNAJC14 HERPUD2 ARID1A NR1D1 PLXNB3 NABP2	3.60e-04	1285	37	7	35914814
Pubmed	A census of human transcription factors: function, expression and evolution.	ONECUT2 KMT2D NR1D1 MTF1 MYRF NR2F1	3.63e-04	908	37	6	19274049
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	NSD1 NR2F1	3.80e-04	27	37	2	37995181
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	NCOA6 NR1D1 NR2F1	3.86e-04	133	37	3	15604093
Pubmed	Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord.	ONECUT2 NR2F1	4.39e-04	29	37	2	30846445
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PCF11 DIDO1 IRS2 PSMD13	5.75e-04	361	37	4	26167880
Pubmed	Inceptor counteracts insulin signalling in β-cells to control glycaemia.	IRS2 ACACA	6.05e-04	34	37	2	33505018
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	NCOA6 KMT2D ARID1A	6.26e-04	157	37	3	30186101
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	PCF11 PAWR IRS2 PYGO2 NR2F1 DNASE2	6.73e-04	1021	37	6	26760575
Pubmed	USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation.	PSMD13 ARID1A	7.16e-04	37	37	2	32133736
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PCF11 KMT2D PSMD13 ARID1A SLC12A7 CDC14A	7.75e-04	1049	37	6	27880917
Pubmed	MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.	RUNX1T1 NR2F1	7.96e-04	39	37	2	36064547
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	MAML1 NCOA6	8.80e-04	41	37	2	8724849
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PCF11 ACACA POM121C	9.31e-04	180	37	3	35198878
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 IRS2 KMT2D ACACA	9.93e-04	418	37	4	34709266
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	NSD1 IRS2 ARID1A DNASE2 SGK2	1.00e-03	730	37	5	34857952
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	PCF11 MAML1 NCOA6 ARID1A	1.06e-03	425	37	4	24999758
Interaction	PAX9 interactions	MAML1 NCOA6 ZNF536 KMT2D PYGO2 ARID1A	1.27e-07	130	37	6	int:PAX9
Interaction	EGR2 interactions	MAML1 NCOA6 ZNF536 KMT2D PYGO2 ARID1A	6.39e-07	171	37	6	int:EGR2
Interaction	SP7 interactions	PCF11 MAML1 NCOA6 ZNF536 KMT2D PYGO2 ARID1A	1.16e-06	304	37	7	int:SP7
Interaction	SMG7 interactions	SECISBP2L PCF11 MAML1 NCOA6 KMT2D PSMD13 ARID1A	1.60e-06	319	37	7	int:SMG7
Interaction	TBR1 interactions	MAML1 ZNF536 KMT2D PYGO2 ARID1A	1.92e-06	113	37	5	int:TBR1
Interaction	TBXT interactions	MAML1 NCOA6 ZNF536 KMT2D ARID1A	2.18e-06	116	37	5	int:TBXT
Interaction	NUP35 interactions	PCF11 MAML1 NCOA6 KMT2D PYGO2 ARID1A POM121C	1.04e-05	424	37	7	int:NUP35
Interaction	TLX1 interactions	MAML1 ZNF536 KMT2D PYGO2 ARID1A	1.62e-05	175	37	5	int:TLX1
Interaction	TOP3B interactions	MAML1 NSD1 NCOA6 IRS2 KMT2D ACACA DNAJC14 ARID1A POM121C MYRF CDC14A	4.35e-05	1470	37	11	int:TOP3B
Interaction	PAX8 interactions	MAML1 KMT2D PYGO2 ARID1A	5.00e-05	111	37	4	int:PAX8
Interaction	ERG interactions	MAML1 NCOA6 KMT2D PYGO2 ARID1A	5.18e-05	223	37	5	int:ERG
Interaction	AR interactions	PCF11 MAML1 NSD1 DIDO1 NCOA6 KMT2D PSMD13 PYGO2 ARID1A	5.84e-05	992	37	9	int:AR
Interaction	PAX7 interactions	MAML1 KMT2D PYGO2 ARID1A	7.71e-05	124	37	4	int:PAX7
Interaction	ASF1A interactions	NSD1 NCOA6 ZNF536 KMT2D ARID1A	8.73e-05	249	37	5	int:ASF1A
Interaction	CRX interactions	MAML1 ZNF536 KMT2D PYGO2 ARID1A	9.58e-05	254	37	5	int:CRX
Interaction	TPRX2 interactions	NCOA6 KMT2D ARID1A	1.48e-04	56	37	3	int:TPRX2
Interaction	TLX3 interactions	MAML1 NCOA6 KMT2D PYGO2 ARID1A	1.81e-04	291	37	5	int:TLX3
Interaction	GCM1 interactions	ZNF536 KMT2D ARID1A	2.63e-04	68	37	3	int:GCM1
Interaction	ETV4 interactions	KMT2D PYGO2 ARID1A	2.75e-04	69	37	3	int:ETV4
Interaction	LHX3 interactions	KMT2D PYGO2 RUNX1T1 ARID1A	3.58e-04	185	37	4	int:LHX3
Interaction	GATA3 interactions	PCF11 ZNF536 KMT2D ARID1A	3.73e-04	187	37	4	int:GATA3
Interaction	HNF1B interactions	MAML1 ZNF536 KMT2D ARID1A	3.96e-04	190	37	4	int:HNF1B
Interaction	KLF5 interactions	MAML1 NCOA6 KMT2D ARID1A	4.37e-04	195	37	4	int:KLF5
Interaction	SOX7 interactions	MAML1 KMT2D ARID1A	4.57e-04	82	37	3	int:SOX7
Interaction	TERF2IP interactions	PCF11 NSD1 DIDO1 NCOA6 ZNF536 ARID1A	4.64e-04	552	37	6	int:TERF2IP
Interaction	GATA2 interactions	NCOA6 ZNF536 KMT2D ARID1A	4.72e-04	199	37	4	int:GATA2
Interaction	IRF4 interactions	KMT2D PYGO2 ARID1A	5.07e-04	85	37	3	int:IRF4
Interaction	FEV interactions	MAML1 NCOA6 KMT2D ARID1A	5.09e-04	203	37	4	int:FEV
Interaction	DAPK3 interactions	PAWR ACACA CDC14A	5.80e-04	89	37	3	int:DAPK3
Interaction	TLE3 interactions	MAML1 KMT2D PYGO2 ARID1A INO80D	5.87e-04	376	37	5	int:TLE3
Interaction	FOXI1 interactions	ZNF536 KMT2D ARID1A	6.39e-04	92	37	3	int:FOXI1
Interaction	HCFC2 interactions	DIDO1 NCOA6 KMT2D	6.39e-04	92	37	3	int:HCFC2
Interaction	YAP1 interactions	NSD1 DIDO1 NCOA6 KMT2D PSMD13 ACACA ARID1A NR1D1	6.97e-04	1095	37	8	int:YAP1
Interaction	SOX17 interactions	NCOA6 KMT2D ARID1A	7.02e-04	95	37	3	int:SOX17
Interaction	CREBBP interactions	MAML1 NCOA6 KMT2D PYGO2 ARID1A MTF1	7.13e-04	599	37	6	int:CREBBP
Interaction	RARA interactions	NSD1 NCOA6 ARID1A NABP2	7.24e-04	223	37	4	int:RARA
Interaction	SOX9 interactions	NCOA6 KMT2D ARID1A	7.46e-04	97	37	3	int:SOX9
Interaction	KLF3 interactions	ZNF536 KMT2D ARID1A SOBP	7.86e-04	228	37	4	int:KLF3
Interaction	UTY interactions	NCOA6 KMT2D	8.10e-04	23	37	2	int:UTY
Interaction	LHX1 interactions	KMT2D PYGO2 ARID1A	8.88e-04	103	37	3	int:LHX1
Interaction	NUP43 interactions	NSD1 NCOA6 KMT2D ACACA ARID1A POM121C	8.90e-04	625	37	6	int:NUP43
Cytoband	5q35	MAML1 NSD1	1.58e-04	23	37	2	5q35
GeneFamily	PHD finger proteins	NSD1 DIDO1 KMT2D PYGO2	3.22e-06	90	21	4	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 KMT2D	7.05e-04	34	21	2	487
GeneFamily	Nuclear hormone receptors	NR1D1 NR2F1	1.46e-03	49	21	2	71
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ASAP3 IRS2	2.35e-02	206	21	2	682
Coexpression	ONDER_CDH1_TARGETS_1_UP	DIDO1 N4BP2L2 SEC24D ZNF226 NR1D1	1.48e-06	139	37	5	M18757
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	SECISBP2L N4BP2L2 NCOA6 SEC24D IRS2 SLC12A7 NR1D1 MTF1	1.56e-05	822	37	8	M6782
Coexpression	GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP	NSD1 IRS2 SLC12A7 CDC14A	1.62e-04	195	37	4	M4201
Coexpression	GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP	MAML1 N4BP2L2 NCOA6 KMT2D	1.65e-04	196	37	4	M5381
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN	MAML1 NCOA6 KMT2D SLC12A7	1.75e-04	199	37	4	M7711
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_DN	DIDO1 PAWR SOBP NR2F1	1.78e-04	200	37	4	M3729
Coexpression	GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP	SECISBP2L MAML1 SEC24D PYGO2	1.78e-04	200	37	4	M5069
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	NSD1 KMT2D INO80D CDC14A	1.78e-04	200	37	4	M9463
Coexpression	GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN	NCOA6 KMT2D HERPUD2 INO80D	1.78e-04	200	37	4	M4876
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	N4BP2L2 HERPUD2 SLC12A7 INO80D	1.78e-04	200	37	4	M7444
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P1\|Thalamus / BrainAtlas - Mouse McCarroll V32	SECISBP2L HERPUD2 MYRF PLXNB3 SGK2	1.39e-07	147	37	5	a21b63d0d3aec9ffadf3fac833a0a24da58a95bf
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF PLXNB3 SGK2	2.18e-06	111	37	4	bb59f1909645fd512f0ea806e5593d4a1c6e25d9
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF PLXNB3 SGK2	2.68e-06	117	37	4	13f068cc4b4a8e9c66bf0e9e5acf9613654bf3f4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF PLXNB3 SGK2	5.03e-06	137	37	4	80f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	ASAP3 ARID1A MTF1 CDC14A	9.75e-06	162	37	4	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	HERPUD2 MYRF PLXNB3 SGK2	1.10e-05	167	37	4	1e144c03409df94ccd39760842590e8ea7487e29
ToppCell	Entopeduncular-Macroglia\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF PLXNB3 SGK2	1.44e-05	179	37	4	f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 ZNF536 NR2F1 PLXNB3	1.54e-05	182	37	4	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	ZNF536 RUNX1T1 SOBP NR2F1	1.94e-05	193	37	4	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF536 MYRF PLXNB3 SGK2	2.06e-05	196	37	4	77feb22fd0b0b1df03375da472134412e9e69c90
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF536 MYRF PLXNB3 SGK2	2.10e-05	197	37	4	032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SECISBP2L ZNF536 MYRF PLCH2	2.10e-05	197	37	4	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF536 MYRF PLXNB3 SGK2	2.10e-05	197	37	4	54fb207638e211f8efdb13003ae62a6b1f003b09
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	MAML1 ZNF536 IRS2 ARID1A	2.19e-05	199	37	4	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 RUNX1T1 HERPUD2 NR2F1	2.23e-05	200	37	4	c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SECISBP2L ZNF536 MYRF PLXNB3	2.23e-05	200	37	4	829978708463a7459fe1041bd90196775bc4b531
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	6.73e-05	95	37	3	0ac6cba7e0ed6083f777287f39a871461fa1bca4
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SECISBP2L PLXNB3 SGK2	8.56e-05	103	37	3	287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	8.80e-05	104	37	3	30b2f6f6612ea45c92f0d466e301d85291a2ee70
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	8.80e-05	104	37	3	a0e03cc97d453050c6b7e6e290ef0babc7bc1276
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	8.80e-05	104	37	3	3cc15f0abdf1f4304af9152911a1f3aab3bc0925
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	1.31e-04	119	37	3	ec3af1253f03b3ec403f73243237acf08ad56789
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	1.45e-04	123	37	3	e0eb95f1da12687230b47f0a7367b6138bc7ff1a
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	1.45e-04	123	37	3	356e2b1b47fdfc2bb2fcd45e44b452fe811f0fd8
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	1.45e-04	123	37	3	15f951b4eb2f39888e51e1af18c329953d253f7f
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	1.45e-04	123	37	3	b06a38d1081b4485b519853d8c9a2cddfb1e9e75
ToppCell	Cerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	1.45e-04	123	37	3	f60c1dd89da0e204f73772fe0c319eeca82e7e8a
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF SGK2	1.78e-04	132	37	3	dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF SGK2	1.78e-04	132	37	3	60ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	1.86e-04	134	37	3	3dd4b5eddc94c1d49ab23b287ee234db3a55331b
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	PCF11 DIDO1 KMT2D	1.91e-04	135	37	3	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	1.99e-04	137	37	3	b03f19b233c1c809f2cd2b4a7642eeaf254a6289
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	1.99e-04	137	37	3	ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SECISBP2L MYRF SGK2	1.99e-04	137	37	3	5e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	2.08e-04	139	37	3	789edd3c98e7c5c1cc402c780fded9a9dfd1dfb8
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1\|Striatum / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	2.30e-04	144	37	3	9d6133558728fa148050eb4f0be33756d71310b0
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SECISBP2L PLXNB3 SGK2	2.40e-04	146	37	3	a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ONECUT2 MYRF SGK2	2.40e-04	146	37	3	e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	2.50e-04	148	37	3	d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	2.50e-04	148	37	3	44128692824ca419fface0af41099c17135933ce
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ONECUT2 MYRF SGK2	2.55e-04	149	37	3	92a8931a51db619fb5f0638d319c02e7838f6559
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	2.60e-04	150	37	3	b30f52b94ce772632a1f2f5e0837db876cf92651
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYRF PLXNB3 SGK2	2.60e-04	150	37	3	05b9a9cbc5a95cdaf45d5f173e132acd4da9aa8a
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 ACACA SGK2	3.14e-04	160	37	3	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	Severe-Lymphoid-NK-CCR7+_T\|Severe / Condition, Lineage, Cell class and cell subclass	PYGO2 CDC14A SGK2	3.31e-04	163	37	3	8f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	DNAJC14 ARID1A INO80D	3.49e-04	166	37	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ONECUT2 MYRF PLXNB3	3.56e-04	167	37	3	1adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ONECUT2 MYRF PLXNB3	3.56e-04	167	37	3	743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZNF536 PAWR MYRF	3.62e-04	168	37	3	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	3.68e-04	169	37	3	50cc0f5a022b95986949db63208a627cef9f4a69
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D RUNX1T1 NR2F1	3.68e-04	169	37	3	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	ZNF536 PAWR MYRF	3.88e-04	172	37	3	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	KLF17 DNAJC14 NR2F1	3.88e-04	172	37	3	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	RUNX1T1 NR2F1 SGK2	3.94e-04	173	37	3	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	Frontal_cortex-Macroglia\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	3.94e-04	173	37	3	ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCell	Substantia_nigra-Macroglia\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	4.01e-04	174	37	3	7e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 RUNX1T1 NR2F1	4.01e-04	174	37	3	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	4.08e-04	175	37	3	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	facs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 SEC24D PAWR	4.15e-04	176	37	3	5f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell	facs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 SEC24D PAWR	4.22e-04	177	37	3	35d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell	Globus_pallidus-Macroglia\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYRF PLXNB3 SGK2	4.36e-04	179	37	3	ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 PAWR PLCH2	4.36e-04	179	37	3	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PAWR ACACA MYRF	4.50e-04	181	37	3	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF536 RUNX1T1 NR2F1	4.65e-04	183	37	3	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAWR SLC12A7 CDC14A	4.65e-04	183	37	3	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.65e-04	183	37	3	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF536 RUNX1T1 NR2F1	4.65e-04	183	37	3	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 PAWR CDC14A	4.65e-04	183	37	3	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.72e-04	184	37	3	5939527d24d299e562e707469c9123890edd76be
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.72e-04	184	37	3	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.79e-04	185	37	3	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RUNX1T1 MYRF NR2F1	4.79e-04	185	37	3	11fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.79e-04	185	37	3	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.87e-04	186	37	3	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.87e-04	186	37	3	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.95e-04	187	37	3	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.95e-04	187	37	3	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	4.95e-04	187	37	3	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	ZNF536 RUNX1T1 NR2F1	4.95e-04	187	37	3	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	5.02e-04	188	37	3	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	5.02e-04	188	37	3	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.02e-04	188	37	3	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.10e-04	189	37	3	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.10e-04	189	37	3	37ecbd73408d462b47d7e5611f203143e08a2689
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 MYRF PLXNB3	5.10e-04	189	37	3	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 RUNX1T1 NR2F1	5.18e-04	190	37	3	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	facs-Heart-RA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAWR NR1D1 NR2F1	5.18e-04	190	37	3	bfbdf16d488359d7935a419c4c1823288f39c183
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.18e-04	190	37	3	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	facs-Heart-RA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAWR NR1D1 NR2F1	5.18e-04	190	37	3	eb1f8bb4d903b08e50c2dc173b06c0c79d8e316e
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAWR SLC12A7 CDC14A	5.18e-04	190	37	3	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D RUNX1T1 NR2F1	5.26e-04	191	37	3	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RUNX1T1 SOBP NR2F1	5.26e-04	191	37	3	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.26e-04	191	37	3	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SECISBP2L MYRF PLXNB3	5.26e-04	191	37	3	d45b6aa64667d29ac043c3987902e7f7ddbcf940
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D RUNX1T1 NR2F1	5.26e-04	191	37	3	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RUNX1T1 SOBP NR2F1	5.26e-04	191	37	3	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRF CDC14A PLXNB3	5.26e-04	191	37	3	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SECISBP2L MYRF PLXNB3	5.34e-04	192	37	3	49a34b55788d7ca955936fff1c0501ed674a9f3c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZNF536 RUNX1T1 NR2F1	5.34e-04	192	37	3	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D IRS2 NR1D1	5.34e-04	192	37	3	0dc1f46e40346ed0b286e53b106a812441575100
Drug	Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ASAP3 MAML1 ONECUT2 IRS2 ARID1A NR1D1 SGK2	2.34e-08	193	37	7	2829_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	ASAP3 DIDO1 SEC24D IRS2 SLC12A7	9.05e-06	175	37	5	5222_UP
Drug	Fillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ONECUT2 N4BP2L2 SEC24D IRS2 CDC14A	1.42e-05	192	37	5	2813_UP
Drug	Fusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 INO80D CDC14A NR2F1	1.49e-05	194	37	5	3245_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	MAML1 ONECUT2 SEC24D ARID1A INO80D	1.53e-05	195	37	5	6059_DN
Drug	chromium chloride	NCOA6 ACACA	1.54e-05	4	37	2	CID000024871
Drug	Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 SEC24D IRS2 CDC14A	1.57e-05	196	37	5	2793_UP
Drug	Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 SEC24D IRS2 INO80D	1.57e-05	196	37	5	2798_UP
Drug	Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A	ASAP3 SEC24D IRS2 RUNX1T1 MYRF	1.57e-05	196	37	5	7240_UP
Drug	Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ASAP3 RUNX1T1 CDC14A PLCH2 SGK2	1.60e-05	197	37	5	3605_UP
Drug	0173570-0000 [211245-44-2]; Up 200; 1uM; MCF7; HT_HG-U133A	ASAP3 MAML1 ONECUT2 INO80D CDC14A	1.60e-05	197	37	5	4715_UP
Drug	Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ONECUT2 PAWR RUNX1T1 CDC14A DNASE2	1.60e-05	197	37	5	4708_UP
Drug	CP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A	MAML1 ONECUT2 MTF1 INO80D CDC14A	1.60e-05	197	37	5	7486_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ASAP3 SEC24D ARID1A INO80D CDC14A	1.60e-05	197	37	5	3399_DN
Drug	Ganciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A	ONECUT2 IRS2 NR1D1 INO80D CDC14A	1.64e-05	198	37	5	5389_DN
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SECISBP2L NSD1 ARID1A NR1D1 CDC14A	1.64e-05	198	37	5	2217_DN
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; HL60; HT_HG-U133A	ASAP3 KMT2D ARID1A SLC12A7 CDC14A	1.64e-05	198	37	5	2519_UP
Drug	Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; MCF7; HT_HG-U133A	PAWR ARID1A NR1D1 INO80D NABP2	1.68e-05	199	37	5	6840_DN
Drug	semustine; Down 200; 100uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 SEC24D INO80D NR2F1	1.68e-05	199	37	5	7487_DN
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 PAWR NR1D1 CDC14A	1.68e-05	199	37	5	6033_DN
Drug	Maprotiline hydrochloride [10347-81-6]; Down 200; 12.8uM; PC3; HT_HG-U133A	SEC24D ARID1A MYRF INO80D CDC14A	1.73e-05	200	37	5	6676_DN
Drug	forskolin; Up 200; 50uM; MCF7; HT_HG-U133A_EA	DIDO1 SEC24D PAWR IRS2	1.20e-04	157	37	4	913_UP
Drug	AC1L2E0P	NSD1 NCOA6 RUNX1T1 NR1D1 NR2F1	1.32e-04	307	37	5	CID000019390
Drug	A37536	NSD1 DNASE2	1.40e-04	11	37	2	CID000130471
Drug	isosteviol	IRS2 ACACA	1.68e-04	12	37	2	ctd:C515747
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	DIDO1 SEC24D IRS2 SLC12A7	1.79e-04	174	37	4	5215_UP
Drug	Mometasone furoate [83919-23-7]; Up 200; 7.6uM; HL60; HG-U133A	SECISBP2L SEC24D IRS2 ACACA	1.83e-04	175	37	4	1746_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	NSD1 DIDO1 NCOA6 ARID1A	1.95e-04	178	37	4	7245_DN
Drug	Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ASAP3 SEC24D IRS2 NR2F1	1.99e-04	179	37	4	2830_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	NSD1 SEC24D ARID1A NR2F1	1.99e-04	179	37	4	2105_DN
Drug	2-amino-4,6-dinitrotoluene	ACACA NR1D1 SGK2	2.01e-04	70	37	3	ctd:C035208
Drug	Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ASAP3 MAML1 IRS2 SGK2	2.04e-04	180	37	4	4776_UP
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	NSD1 DIDO1 ARID1A NR2F1	2.08e-04	181	37	4	7077_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	NCOA6 ACACA ARID1A NR2F1	2.12e-04	182	37	4	1891_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SECISBP2L PCF11 IRS2 SOBP	2.12e-04	182	37	4	947_DN
Drug	Quercetine dihydrate [6151-25-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ONECUT2 IRS2 NR1D1 MTF1	2.21e-04	184	37	4	2859_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	DIDO1 N4BP2L2 SEC24D IRS2	2.26e-04	185	37	4	6986_UP
Drug	ethyl caproate	NCOA6 ACACA	2.31e-04	14	37	2	CID000031265
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	ASAP3 SEC24D IRS2 ACACA	2.40e-04	188	37	4	7124_UP
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	ASAP3 MAML1 INO80D NR2F1	2.45e-04	189	37	4	2231_UP
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A	ASAP3 SECISBP2L IRS2 ARID1A	2.50e-04	190	37	4	4362_DN
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	DIDO1 SEC24D SLC12A7 CDC14A	2.55e-04	191	37	4	5953_UP
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	PCF11 ARID1A MTF1 SOBP	2.60e-04	192	37	4	1638_DN
Drug	PNU-0251126 [267429-19-6]; Up 200; 10uM; MCF7; HT_HG-U133A	ONECUT2 PAWR INO80D CDC14A	2.60e-04	192	37	4	4711_UP
Drug	Monobenzone [103-16-2]; Down 200; 20uM; HL60; HT_HG-U133A	DIDO1 ARID1A NR1D1 CDC14A	2.60e-04	192	37	4	3054_DN
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	ONECUT2 RUNX1T1 ARID1A PLCH2	2.66e-04	193	37	4	3347_UP
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A	MAML1 PAWR INO80D CDC14A	2.66e-04	193	37	4	4725_UP
Drug	Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A	IRS2 NR1D1 INO80D NR2F1	2.71e-04	194	37	4	5448_DN
Drug	Phenacetin [62-44-2]; Down 200; 22.4uM; MCF7; HT_HG-U133A	PAWR IRS2 CDC14A NR2F1	2.71e-04	194	37	4	4111_DN
Drug	Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	SECISBP2L MAML1 CDC14A SGK2	2.71e-04	194	37	4	6835_UP
Drug	Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT_HG-U133A	SEC24D IRS2 NR1D1 INO80D	2.71e-04	194	37	4	3861_DN
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A	MAML1 ONECUT2 SEC24D ARID1A	2.71e-04	194	37	4	3539_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	ASAP3 PAWR INO80D CDC14A	2.71e-04	194	37	4	3422_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	ASAP3 ONECUT2 NR1D1 CDC14A	2.71e-04	194	37	4	5056_UP
Drug	Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A	MAML1 IRS2 CDC14A NR2F1	2.71e-04	194	37	4	6076_DN
Drug	alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA	SECISBP2L DIDO1 SEC24D NABP2	2.71e-04	194	37	4	990_DN
Drug	Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; MCF7; HT_HG-U133A	ONECUT2 DIDO1 PAWR NR1D1	2.76e-04	195	37	4	7037_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; HL60; HG-U133A	N4BP2L2 SEC24D NR1D1 INO80D	2.76e-04	195	37	4	1981_DN
Drug	Enilconazole [35554-44-0]; Up 200; 13.4uM; PC3; HT_HG-U133A	RUNX1T1 INO80D CDC14A PLCH2	2.76e-04	195	37	4	5113_UP
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	MAML1 SEC24D PAWR NR2F1	2.76e-04	195	37	4	4737_DN
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; HL60; HG-U133A	DIDO1 SEC24D ACACA INO80D	2.76e-04	195	37	4	2017_DN
Drug	Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A	ASAP3 IRS2 CDC14A SGK2	2.76e-04	195	37	4	2790_UP
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; MCF7; HT_HG-U133A	ASAP3 SECISBP2L IRS2 NR2F1	2.76e-04	195	37	4	4402_DN
Drug	arachidonyl trifluoromethyl ketone; Up 200; 10uM; MCF7; HG-U133A	N4BP2L2 PSMD13 ARID1A DNASE2	2.76e-04	195	37	4	327_UP
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 IRS2 INO80D	2.76e-04	195	37	4	3237_DN
Drug	0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A	ASAP3 ZNF536 ARID1A INO80D	2.76e-04	195	37	4	3969_UP
Drug	AC1L1BEH	PAWR RUNX1T1 NR2F1	2.76e-04	78	37	3	CID000001404
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A	ASAP3 SEC24D NR1D1 NR2F1	2.82e-04	196	37	4	3844_DN
Drug	Edrophonium chloride [116-38-1]; Down 200; 19.8uM; HL60; HG-U133A	MAML1 DIDO1 ACACA SLC12A7	2.82e-04	196	37	4	2019_DN
Drug	Fillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 PAWR INO80D	2.82e-04	196	37	4	4172_DN
Drug	Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 INO80D NR2F1	2.82e-04	196	37	4	3360_UP
Drug	Glycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 NR1D1 NABP2	2.82e-04	196	37	4	3315_UP
Drug	Clorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	DIDO1 RUNX1T1 CDC14A NABP2	2.82e-04	196	37	4	2884_UP
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	ONECUT2 PAWR CDC14A NR2F1	2.82e-04	196	37	4	6029_DN
Drug	Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	MAML1 RUNX1T1 CDC14A NR2F1	2.82e-04	196	37	4	2288_DN
Drug	Lobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A	MTF1 MYRF NABP2 SGK2	2.82e-04	196	37	4	1770_UP
Drug	Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A	ARID1A INO80D NR2F1 NABP2	2.82e-04	196	37	4	7015_UP
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SEC24D IRS2 ARID1A NR2F1	2.82e-04	196	37	4	4739_DN
Drug	Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	N4BP2L2 IRS2 RUNX1T1 MYRF	2.82e-04	196	37	4	7251_UP
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A	SECISBP2L MAML1 CDC14A NR2F1	2.82e-04	196	37	4	4747_DN
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; HL60; HG-U133A	ACACA NR1D1 MTF1 INO80D	2.82e-04	196	37	4	1716_DN
Drug	Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	MAML1 ONECUT2 RUNX1T1 CDC14A	2.82e-04	196	37	4	4720_UP
Drug	Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	ASAP3 MYRF CDC14A SGK2	2.82e-04	196	37	4	6673_DN
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; HL60; HG-U133A	MAML1 SEC24D RUNX1T1 INO80D	2.82e-04	196	37	4	1964_DN
Drug	Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; HL60; HT_HG-U133A	SEC24D RUNX1T1 INO80D CDC14A	2.82e-04	196	37	4	2331_UP
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	ONECUT2 PAWR IRS2 NR2F1	2.82e-04	196	37	4	5016_DN
Drug	Chlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 NR2F1 PLCH2	2.82e-04	196	37	4	3210_UP
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	DIDO1 SEC24D CDC14A DNASE2	2.82e-04	196	37	4	2974_DN
Drug	PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A	ASAP3 MYRF CDC14A SGK2	2.82e-04	196	37	4	5979_UP
Drug	Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A	ASAP3 INO80D CDC14A NR2F1	2.82e-04	196	37	4	3253_UP
Drug	Aldosterone	NSD1 NCOA6 MTF1	2.87e-04	79	37	3	ctd:D000450
Drug	CP-645525-01 [287190-82-3]; Down 200; 10uM; MCF7; HT_HG-U133A	ONECUT2 CDC14A SOBP NR2F1	2.87e-04	197	37	4	7522_DN
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 INO80D CDC14A	2.87e-04	197	37	4	6060_DN
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; HL60; HG-U133A	RUNX1T1 MTF1 MYRF NABP2	2.87e-04	197	37	4	1774_UP
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A	ASAP3 MAML1 SEC24D NR2F1	2.87e-04	197	37	4	5449_DN
Drug	Mometasone furoate [83919-23-7]; Down 200; 7.6uM; HL60; HG-U133A	DIDO1 ARID1A MTF1 INO80D	2.87e-04	197	37	4	1746_DN
Drug	Benfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ASAP3 SEC24D INO80D NR2F1	2.87e-04	197	37	4	3837_DN
Drug	Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ASAP3 ONECUT2 PAWR CDC14A	2.87e-04	197	37	4	6482_UP
Drug	Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A	SECISBP2L NSD1 PAWR IRS2	2.87e-04	197	37	4	3171_DN
Drug	Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A	ASAP3 MAML1 NR1D1 INO80D	2.87e-04	197	37	4	7520_UP
Disease	neuroblastoma (is_implicated_in)	NSD1 ARID1A	6.47e-05	10	36	2	DOID:769 (is_implicated_in)
Disease	Microphthalmos	KMT2D MYRF	7.90e-05	11	36	2	C0026010
Disease	T-Cell Lymphoma	KMT2D ARID1A	1.72e-04	16	36	2	C0079772
Disease	Sezary Syndrome	KMT2D ARID1A	4.98e-04	27	36	2	C0036920
Disease	Bladder Neoplasm	KMT2D ARID1A SLC12A7	6.66e-04	140	36	3	C0005695
Disease	Malignant neoplasm of urinary bladder	KMT2D ARID1A SLC12A7	6.79e-04	141	36	3	C0005684
Disease	colon cancer (is_implicated_in)	NCOA6 ARID1A	8.88e-04	36	36	2	DOID:219 (is_implicated_in)
Disease	suicide behaviour	RUNX1T1 HERPUD2	1.33e-03	44	36	2	EFO_0007623
Disease	Colorectal Carcinoma	ASAP3 RUNX1T1 ACACA ARID1A CDC14A	1.54e-03	702	36	5	C0009402
Disease	Male sterility	KMT2D CDC14A	1.58e-03	48	36	2	C0917731
Disease	Male infertility	KMT2D CDC14A	1.58e-03	48	36	2	C0021364
Disease	Subfertility, Male	KMT2D CDC14A	1.58e-03	48	36	2	C0848676
Disease	Endometrial Neoplasms	PAWR ARID1A	2.29e-03	58	36	2	C0014170
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	IRS2 ACACA	2.87e-03	65	36	2	DOID:0080208 (biomarker_via_orthology)
Disease	Endometrial Carcinoma	PAWR ARID1A	3.51e-03	72	36	2	C0476089
Disease	hemoglobin A1 measurement	IRS2 SLC12A7 MTF1 CDC14A	3.59e-03	520	36	4	EFO_0007629
Disease	QT interval	ASAP3 HERPUD2 SLC12A7 MYRF	3.95e-03	534	36	4	EFO_0004682
Disease	cleft lip	NSD1 ZNF536 HERPUD2	4.98e-03	284	36	3	EFO_0003959
Disease	QRS duration	N4BP2L2 HERPUD2 MYRF	5.69e-03	298	36	3	EFO_0005055
Disease	Squamous cell carcinoma of esophagus	DIDO1 KMT2D	6.02e-03	95	36	2	C0279626
Disease	neutrophil count	MAML1 NSD1 ARID1A SLC12A7 MYRF CDC14A	6.08e-03	1382	36	6	EFO_0004833

Protein segments in the cluster

Peptide	Gene	Start	Entry
AFANGQDFGQPLPGP	ASAP3	566	Q8TDY4
NSNGGNLNSPPGPHS	CDC14A	541	Q9UNH5
VPVPGGPNNNNYANV	ACACA	176	Q13085
PFGNGQSNFSEPLNG	NSD1	31	Q96L73
ANELNNNLPGGAPAA	PAWR	66	Q96IZ0
PNPGQYALTNGDPLN	NR2F1	166	P10589
GNPGQQAQAPSAAGP	PALM2	256	Q8IXS6
RPAGGPQNQFPFQFG	ARID1A	1446	O14497
PQNGDQQNGYGDLFP	MAML1	121	Q92585
GNFFAAPQPAPGAAA	DNAJC14	661	Q6Y2X3
ALNGAPSPPNGFSNG	RUNX1T1	86	Q06455
AHAPQPANGSGLPQF	PLXNB3	1211	Q9ULL4
NAQQSLPNYGPPGHD	ONECUT2	241	O95948
GFLQQSQNSGPGQPA	PSMD13	6	Q9UNM6
PGANPQPAFGAAEGQ	POM121C	941	A8CG34
NDPPGNAFNAPSQGL	PCF11	1136	O94913
EQIFDSPQGPNFNGP	PCF11	1156	O94913
HPQNPGFVQNPSGAL	PCF11	1241	O94913
PFNQPLGQNFSPPSG	PYGO2	166	Q9BRQ0
AAAVNGNQPSFPPNS	PYGO2	281	Q9BRQ0
VPGSFPNNSGLNPQN	NCOA6	1386	Q14686
GPASGDGPNLNNNNN	IRS2	11	Q9Y4H2
PGNFNANHASGSPPA	NR1D1	311	P20393
VNQIAFPGPAGPSFN	DNASE2	276	O00115
HPNQFEGPRGQAPNF	DIDO1	1941	Q9BTC0
GNLPVNLGDPSPFSN	INO80D	891	Q53TQ3
RPGPSDPQANNNNGE	KLF17	366	Q5JT82
NVDNQFPGQAAPPGF	HERPUD2	166	Q9BSE4
PGDGNPRENSPFLNN	SLC12A7	41	Q9Y666
ANGNINLGPSANPNA	SGK2	16	Q9HBY8
NLGPSANPNAQPTDF	SGK2	21	Q9HBY8
PGSQQAAFGNPPALL	MTF1	451	Q14872
NNQPAAGALRNPDSG	SECISBP2L	281	Q93073
LGAGYPPQQANSGPQ	SEC24D	216	O94855
PPNGFSSNGENFIPN	SOBP	551	A7XYQ1
QGVFNPNSEDPLPGQ	PLCH2	741	O75038
ASENQNGNGLSAPPG	NABP2	146	Q9BQ15
QNGAGPLSGQPPNQD	ZNF536	806	O15090
NKADGPNNTGNPEFP	ZNF226	151	Q9NYT6
GQPGGPFLNTALAQQ	KMT2D	3666	O14686
GPPNPPSNIFQAQDD	N4BP2L2	296	Q92802
PPPGYGTPLNCNNNN	MYRF	91	Q9Y2G1