Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionproteasome-activating activity

PSMC1 PSMC3

9.53e-056512GO:0036402
GeneOntologyCellularComponentP-body

AGO3 SYNE1 PSMC3 CPEB1

1.12e-04102514GO:0000932
GeneOntologyCellularComponentproteasome regulatory particle, base subcomplex

PSMC1 PSMC3

3.79e-0412512GO:0008540
DomainActinin_actin-bd_CS

FLNA FLNC SYNE1

3.08e-0523503IPR001589
DomainACTININ_2

FLNA FLNC SYNE1

3.08e-0523503PS00020
DomainACTININ_1

FLNA FLNC SYNE1

3.08e-0523503PS00019
Domain26S_Psome_P45

PSMC1 PSMC3

1.05e-046502IPR005937
Domain-

DPP4 DPP9

1.05e-0465022.140.10.30
DomainDPPIV_N

DPP4 DPP9

1.05e-046502PF00930
DomainPeptidase_S9B_N

DPP4 DPP9

1.05e-046502IPR002469
DomainIG_FLMN

FLNA FLNC

3.12e-0410502SM00557
DomainFilamin

FLNA FLNC

3.80e-0411502PF00630
DomainFilamin/ABP280_rpt

FLNA FLNC

3.80e-0411502IPR001298
DomainPeptidase_S9

DPP4 DPP9

3.80e-0411502PF00326
DomainFilamin/ABP280_repeat-like

FLNA FLNC

3.80e-0411502IPR017868
DomainPeptidase_S9

DPP4 DPP9

3.80e-0411502IPR001375
DomainFILAMIN_REPEAT

FLNA FLNC

3.80e-0411502PS50194
DomainCH

FLNA FLNC SYNE1

7.02e-0465503SM00033
DomainCH

FLNA FLNC SYNE1

8.71e-0470503PF00307
Domain-

FLNA FLNC SYNE1

9.08e-04715031.10.418.10
DomainCH

FLNA FLNC SYNE1

9.84e-0473503PS50021
DomainCH-domain

FLNA FLNC SYNE1

1.06e-0375503IPR001715
DomainATPase_AAA_CS

PSMC1 PSMC3

2.72e-0329502IPR003960
DomainUBA

USP13 VPS13D

2.91e-0330502SM00165
DomainAAA

PSMC1 PSMC3

3.73e-0334502PS00674
DomainUBA

USP13 VPS13D

4.18e-0336502PF00627
DomainUBA

USP13 VPS13D

6.18e-0344502IPR015940
DomainAAA+_ATPase

GPN1 PSMC1 PSMC3

6.75e-03144503IPR003593
DomainAAA

GPN1 PSMC1 PSMC3

6.75e-03144503SM00382
DomainUBA

USP13 VPS13D

7.03e-0347502PS50030
DomainAAA

PSMC1 PSMC3

8.55e-0352502PF00004
DomainATPase_AAA_core

PSMC1 PSMC3

9.20e-0354502IPR003959
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

2.11e-0625127689010
Pubmed

[Rare forms of autosomal recessive spinocerebellar ataxia associated with mutations in the ANO10 (ATX-ANO10) and SYNE1 (ATX-SYNE1) genes].

SYNE1 ANO10

2.11e-06251239269294
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

2.11e-06251210679933
Pubmed

Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9.

DPP4 DPP9

2.11e-06251222001206
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

2.11e-06251224469451
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

KDM3A FLNA FLNC CDSN GPN1 SEC24B PSMC3

3.76e-0644451734795231
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ATP5PB FLNA FLNC SYNE1 TMEM135 HKDC1 BSN YY1 THRAP3 PRRC2B MYBPC2

6.19e-061442511135575683
Pubmed

Isoforms of dipeptidyl aminopeptidase IV from Pseudomonas sp. WO24: role of the signal sequence and overexpression in Escherichia coli.

DPP4 DPP9

6.32e-06351215866709
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNC

6.32e-06351211252955
Pubmed

The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.

FLNA FLNC

6.32e-06351212704190
Pubmed

The effect of CD26-deficiency on dipeptidyl peptidase 8 and 9 expression profiles in a mouse model of Crohn's disease.

DPP4 DPP9

6.32e-06351229693275
Pubmed

A prominent and conserved role for YY1 in Xist transcriptional activation.

ZFP42 YY1

6.32e-06351225209548
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNA FLNC

6.32e-06351211038172
Pubmed

Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

FLNA FLNC

6.32e-06351211102480
Pubmed

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

DPP4 DPP9

6.32e-06351223608773
Pubmed

Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.

FLNA FLNC

6.32e-06351217825253
Pubmed

Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.

OR2A7 OR2A4

6.32e-06351227315375
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNC

6.32e-06351212393796
Pubmed

Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.

DPP4 DPP9

6.32e-06351216704418
Pubmed

Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

FLNA FLNC

6.32e-0635129412467
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNC

6.32e-06351211153914
Pubmed

Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family.

PSMC1 PSMC3

6.32e-0635121429620
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

PLSCR4 ARHGEF10 SYNE1 SEC24B PSMC1 MFSD8 BACE2 MYRF

9.33e-0671951835337019
Pubmed

The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.

FLNA FLNC

1.26e-05451220554076
Pubmed

Expression of dipeptidyl peptidase-IV activity and/or structure homologs in human meningiomas.

DPP4 DPP9

1.26e-05451220043068
Pubmed

A zonal organization of odorant receptor gene expression in the olfactory epithelium.

OR2A7 OR2A4

1.26e-0545127683976
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNC

1.26e-05451211739414
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNC

1.26e-05451222802962
Pubmed

DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk.

FLNA DPP9

1.26e-05451227614019
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

KDM3A FLNA FLNC USP13 ARHGEF10 GPN1 PSMC1 PSMC3 PRRC2B

1.39e-05100551919615732
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

FLNA FLNC CDSN RIPK1 PSMC1 PSMC3 THRAP3

1.66e-0555851727591049
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

DPP4 FLNA FLNC VPS13D NOL10 THRAP3 MYBPC2

1.77e-0556451721565611
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNA PPP1R2B FLNC VPS13D SEC24B ANO10 ALG13

1.86e-0556851737774976
Pubmed

Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.

DPP4 DPP9

2.10e-05551220534982
Pubmed

Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease.

NAT2 RIPK1

2.10e-05551233296651
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNA FLNC

2.10e-05551219366992
Pubmed

Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.

DPP4 DPP9

2.10e-05551223704821
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNA FLNC

2.10e-05551212006559
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNA FLNC

2.10e-05551217360453
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

ATP5PB FLNA FLNC PSMC1 PSMC3 THRAP3

2.90e-0540851633766124
Pubmed

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.

FLNA FLNC

3.15e-0565129006895
Pubmed

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

FLNA FLNC

3.15e-05651212679033
Pubmed

ASK1 negatively regulates the 26 S proteasome.

PSMC1 PSMC3

3.15e-05651220843792
Pubmed

Chromosomal localization and immunological analysis of a family of human 26S proteasomal ATPases.

PSMC1 PSMC3

3.15e-0565129473509
Pubmed

Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.

PSMC1 PSMC3 YY1

4.04e-054551318922472
Pubmed

HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.

FLNA FLNC

4.41e-05751226929074
Pubmed

Structure of the human 26S proteasome at a resolution of 3.9 Å.

PSMC1 PSMC3

4.41e-05751227342858
Pubmed

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

FLNA FLNC

4.41e-05751216076904
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ATP5PB VPS13D SYNE1 SEC24B TMEM135 PSMC1 PSMC3 NOL10 PRRC2B ALG13

5.36e-051496511032877691
Pubmed

C termini of proteasomal ATPases play nonequivalent roles in cellular assembly of mammalian 26 S proteasome.

PSMC1 PSMC3

5.87e-05851221628461
Pubmed

Saturation mutagenesis defines novel mouse models of severe spine deformity.

OR2A7 OR2A4

5.87e-05851234142127
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

FLNA FLNC

5.87e-05851217145501
Pubmed

HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity.

FLNA FLNC

5.87e-05851228827800
Pubmed

Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stability.

PSMC3 YY1

5.87e-05851222659184
Pubmed

Case-control genome-wide association study of attention-deficit/hyperactivity disorder.

FLNC HKDC1

5.87e-05851220732627
Pubmed

Parkin directly modulates 26S proteasome activity.

PSMC1 PSMC3

7.54e-05951220810900
Pubmed

Comparative mapping of the actin-binding protein 280 genes in human and mouse.

FLNA FLNC

7.54e-0595128088838
Pubmed

Regulation of the anaphase-promoting complex by the COP9 signalosome.

PSMC1 PSMC3

7.54e-05951219535905
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

FLNA FLNC

7.54e-05951211807098
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

FLNA FLNC AGO3 SEC24B PSMC1 PSMC3

8.35e-0549451626831064
Pubmed

Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method.

USP13 PSMC1 PSMC3

8.66e-055851319013454
Pubmed

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

FLNC MYBPC2

9.42e-051051219506036
Pubmed

Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases.

PSMC1 PSMC3

9.42e-051051215831487
Pubmed

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

FLNA RIPK1 PSMC1 PSMC3

9.56e-0516251414743216
Pubmed

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.

ATP5PB FLNA CDSN PSMC1 PSMC3

1.06e-0432051528685749
Pubmed

Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.

FLNA FLNC

1.15e-041151236579465
Pubmed

Stable incorporation of ATPase subunits into 19 S regulatory particle of human proteasome requires nucleotide binding and C-terminal tails.

PSMC1 PSMC3

1.15e-041151222275368
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

FLNA FLNC PSMC1 PSMC3 NOL10

1.30e-0433451530425250
Pubmed

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.

CDSN PSMC3 THRAP3

1.33e-046751329863498
Pubmed

Mdm2 facilitates the association of p53 with the proteasome.

PSMC1 PSMC3

1.38e-041251220479273
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

FLNA FLNC CDSN UAP1 GPN1 PSMC1 ANO10 THRAP3 PRRC2B

1.49e-04136751932687490
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR2A7 OR2A4

1.63e-041351211014824
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

FLNA AGO3 SYNE1 NOL10 THRAP3 PRRC2B ALG13

1.68e-0480751722681889
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ATP5PB FLNA FLNC UAP1 SYNE1 PSMC3 ALG13

1.68e-0480751730575818
Pubmed

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

FLNA PSMC1 PSMC3

1.72e-047351330224337
Pubmed

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.

OR2A7 OR2A4

1.90e-04145127528109
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

SYNE1 SEC24B YY1 THRAP3

2.03e-0419751420811636
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ATP5PB FLNA CDSN SYNE1 PSMC1 PSMC3 NOL10 BSN THRAP3

2.04e-04142551930948266
Pubmed

Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.

ATP5PB PSMC3 DNAJB5 THRAP3

2.07e-0419851424337577
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP5PB FLNA FLNC SYNE1 PSMC1 PSMC3 BSN THRAP3 PRRC2B

2.10e-04143151937142655
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

ATP5PB FLNA FLNC PSMC1 PSMC3 HKDC1 THRAP3

2.26e-0484751735235311
Pubmed

CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase.

PSMC1 PSMC3

2.50e-041651229979702
Pubmed

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

HKDC1 BACE2

2.50e-041651223903356
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FLNA COL8A2 DPP9

2.70e-048551315449545
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNA FLNC RIPK1 SYNE1

2.78e-0421451422199357
Pubmed

Defining the membrane proteome of NK cells.

ATP5PB KDM3A DPP4 FLNA AGO3 PSMC1 PSMC3 ANO10

2.79e-04116851819946888
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

FLNA FLNC GPN1 THRAP3

2.83e-0421551435973513
Pubmed

Different roles of Runx2 during early neural crest-derived bone and tooth development.

IGFBP3 ENPP1

2.83e-041751216813524
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

USP13 PSMC1 PSMC3

2.89e-048751317148452
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNA FLNC

3.18e-041851212119179
Pubmed

Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.

YY1 MYRF

3.18e-041851223575864
Pubmed

Hereditary Ataxia Overview

VPS13D SYNE1 ANO10

3.40e-049251320301317
Pubmed

Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development.

FLNA FLNC

3.55e-041951229374072
Pubmed

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

PSMC1 PSMC3

3.55e-041951219490896
Pubmed

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

RIPK1 ALG13

3.55e-041951223827681
Pubmed

OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways.

FLNC RIPK1

3.55e-041951235941131
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

IGFBP3 HKDC1 MFSD8 MYRF

3.83e-0423351432290105
Pubmed

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.

PSMC1 PSMC3 DNAJB5

3.86e-049651334599178
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

ATP5PB FLNA PSMC1 PSMC3 THRAP3 ALG13

3.89e-0465751636180527
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA SYNE1 YY1 THRAP3

3.89e-0423451436243803
InteractionCARD8 interactions

FLNA FLNC DPP9 PIPOX

1.48e-0560504int:CARD8
InteractionR3HDM2 interactions

AGO3 SEC24B PRRC2B CPEB1 ALG13

1.67e-05129505int:R3HDM2
InteractionNPHP4 interactions

FLNA FLNC VPS13D NOL10 THRAP3 MYBPC2

2.50e-05236506int:NPHP4
GeneFamilyCD molecules|DASH family

DPP4 DPP9

5.56e-0573021205
GeneFamilyProteasome

PSMC1 PSMC3

2.30e-0343302690
GeneFamilyAAA ATPases

PSMC1 PSMC3

3.48e-0353302413
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF10 ARHGEF38

5.34e-0366302722
GeneFamilyOlfactory receptors, family 2

OR2A7 OR2A4

1.50e-02113302149
CoexpressionGSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN

DPP4 SYNE1 DTX4 PSMC3 DNA2

1.09e-05150515M6749
CoexpressionGSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP

NAT2 GPN1 BACE2 QTRT1 MYBPC2

4.24e-05199515M9366
CoexpressionGSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN

UAP1 ENPP1 GPN1 PRRC2B ALG13

4.35e-05200515M8384
CoexpressionGSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP

FLNA ARHGEF10 ANO10 THRAP3 PRRC2B

4.35e-05200515M5711
CoexpressionMANALO_HYPOXIA_UP

KDM3A IGFBP3 TMEM45A ENPP1 BACE2

4.89e-05205515M259
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP4 COL8A2 ZFP42 IGFBP3 ARHGEF10

1.66e-0617451546bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

OR2A7 TMEM45A DTX4 ARHGEF38 HKDC1

2.98e-06196515d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLSCR4 FLNA IGFBP3 TMEM45A QTRT1

3.28e-06200515ac5843142e0f8a5bcd2c3a784ea13b2f955a32fd
ToppCellMild/Remission-B_naive-13|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DPP4 ENPP1 ONECUT3 BACE2

2.12e-0514251449873a2d9b1ae4bdbf253d1c09bf8845cc0cc917
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 TMEM45A ENPP1

3.81e-05165514570483b43ccb5831feec9337b4664814431d40b1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 TMEM45A ENPP1

3.81e-051655142026a9a07f4d314cc05c167e491312b373468e46
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM45A DTX4 BACE2 MYRF

4.18e-05169514aec97583b23112060437b619cb429dc32f29285f
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPP4 RIPK1 SEC24B TMEM135

4.48e-05172514a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC IGFBP3 DNAJB5

5.12e-05178514e5e5f5b4a27e120a1076b1cb250fa25d0c336956
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC IGFBP3 DNAJB5

5.12e-05178514c661246269ce26c4fc62e12f86c5f90a2dcfdce0
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PLSCR4 DPP4 FLNC BACE2

6.59e-05190514103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCellwk_08-11-Mesenchymal-Mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DPP4 FLNC COL8A2 MYRF

7.29e-051955149016a44b521214546a55a822ebdef5b5312206d2
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL8A2 IGFBP3 TMEM45A BACE2

7.29e-05195514febe746099964b9ea9e75f2efc72c962c01f0421
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 TMEM45A DTX4 BACE2

7.44e-051965148e909c31733762646359fe78b645cbd60237459e
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IGFBP3 TMEM45A DTX4 BACE2

7.58e-05197514a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLSCR4 FLNC USP13 SYNE1

7.73e-0519851499d6a64f3410dae3019161feef20a8f06081a24b
ToppCell368C-Fibroblasts-Fibroblast-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

PLSCR4 UAP1 IGFBP3 TMEM45A

7.89e-051995145a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 USP13 SYNE1 ARHGEF38

7.89e-051995142dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell368C-Fibroblasts-Fibroblast-D|368C / Donor, Lineage, Cell class and subclass (all cells)

PLSCR4 UAP1 IGFBP3 TMEM45A

7.89e-0519951466545eb7f65e450b742628fd431956e13330a0d3
ToppCellBAL-Control-cDC_7|Control / Compartment, Disease Groups and Clusters

UAP1 TMEM135 DNAJB5

3.60e-04121513b49b044a687a31883dfccecf10a183b5ba567f7a
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

3.60e-041215135035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

3.60e-04121513c96115bd33455296378a257583b49442d00b39ca
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

4.05e-04126513f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

4.05e-04126513fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

4.05e-041265131ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

4.05e-041265132de551d7a8765afec1da8852727c79fec90f45f8
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

4.05e-041265133d507f829882d043f633db2612b76936e2042445
ToppCelldroplet-Heart-HEART-1m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13D AGO3 NOL10

4.14e-04127513983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLNC TMEM45A ENPP1

4.34e-04129513856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

FLNC TMEM45A ENPP1

4.85e-04134513b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IGFBP3 TMEM45A PIPOX

5.62e-041415137ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A2 ENPP1 DNA2

5.86e-04143513b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ARHGEF38 HKDC1 MYRF

6.22e-04146513e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

ARHGEF10 ENPP1 SYNE1

6.34e-04147513baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLNC ENPP1 DTX4

6.60e-04149513dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC AGO3 MYRF

6.73e-04150513afd651c654e715414eff64cf3a37378d057a56a2
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

ENPP1 SYNE1 MYRF

6.99e-04152513451745151322c2fcea22dbb3dba681e12634a510
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 MYBPC2

7.12e-04153513151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA COL8A2 SYNE1

7.12e-04153513cb144b8c487286384b47fdff88ff98fcf0508899
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLNC TMEM45A ENPP1

7.26e-0415451365dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

FLNC TMEM45A ENPP1

7.96e-0415951392049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP13 DTX4 CPEB1

7.96e-041595137ed659163f45e0c4df4782997c0786900c8186c8
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

DPP4 ENPP1 PIPOX

8.26e-041615139fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA UAP1 SYNE1

8.26e-04161513bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

ZFP42 ENPP1 BSN

8.71e-041645139b4a6007abae992db871d9f6f731d5af724de30d
ToppCellCOVID-19-lung-Mesothelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP4 MYRF CPEB1

8.71e-0416451383303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCellcontrol-Plasmablast|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UAP1 ZFP42 BACE2

8.86e-0416551361063e0ce61bc92d5d1093be8279af03f650720b
ToppCellTuft-tuft-1|World / Class top

USP13 GPN1 ANO10

9.34e-041685138ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

PLSCR4 CTNNAL1 IGFBP3

9.34e-04168513aca34c51758c65925ad24110294a72b2dea6db72
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

DPP4 BACE2 CPEB1

9.34e-04168513c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 DPP9 HKDC1

9.34e-0416851308f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 TMEM45A BACE2

9.50e-0416951358136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCellfacs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 TMEM45A BACE2

9.50e-04169513d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

IGFBP3 TMEM45A BACE2

9.50e-0416951303b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNAL1 TMEM45A BACE2

9.50e-041695138dba7546adc6b1345933eec81fc77fc9611fae60
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 TMEM45A BACE2

9.50e-0416951304c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 IGFBP3 TMEM45A

9.66e-04170513fed8e982d2ce234c59d4016432ed8941df36df27
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGFBP3 TMEM45A MYRF

9.83e-0417151325c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 MYRF CPEB1

9.83e-04171513d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGFBP3 TMEM45A MYRF

9.83e-04171513fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DPP4 ENPP1 BACE2

9.83e-0417151370963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

DPP4 ENPP1 HKDC1

9.99e-0417251347865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DPP4 ENPP1 BACE2

9.99e-0417251384d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 IGFBP3 AGO3

1.02e-0317351303b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 IGFBP3 AGO3

1.02e-0317351312da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM45A PSMC3 DNAJB5

1.02e-03173513176d7dc103b8161c4e2d7dc74f2dc77ea1f2d2ed
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC IGFBP3

1.02e-031735133001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC IGFBP3

1.02e-03173513c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCellPND28-Endothelial-Endothelial_lymphatic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 IGFBP3 AGO3

1.02e-031735132978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 IGFBP3 AGO3

1.02e-0317351323d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 IGFBP3 ENPP1

1.03e-03174513912a9e892b29d945666fc37c986009c97c668ac8
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC IGFBP3 MYBPC2

1.03e-031745134da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP4 FLNC UAP1

1.03e-031745131d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC DNAJB5

1.05e-03175513c6c0196875f3b5293083cda6718300806a801941
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC DNAJB5

1.05e-0317551382c4d1edaa0d3b82d3ef4676d6f6516104a2656a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPP4 ARHGEF10 SYNE1

1.05e-03175513cc2428150987911d0d382e8177918724aa69f85c
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IGFBP3 ARHGEF10 BACE2

1.07e-0317651308f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC COL8A2

1.09e-0317751388403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UAP1 TMEM45A ARHGEF38

1.09e-03177513a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A2 TMEM45A ENPP1

1.09e-03177513915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLNC TMEM45A ENPP1

1.09e-03177513599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC COL8A2

1.09e-031775138903aeaab61abd81a148ea623038c5114b8a183b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA IGFBP3 SYNE1

1.09e-0317751384930899eb2978598bc8a351cbcd9e714e46799d
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UAP1 TMEM45A ARHGEF38

1.09e-03177513363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC IGFBP3 MYRF

1.10e-03178513c413861148129be1ee94f2ceb5999840217eebe5
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLSCR4 FLNC CTNNAL1

1.10e-031785134b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCell(06)_Krt4/13+|World / shred by cell type and Timepoint

IGFBP3 TMEM45A BACE2

1.10e-0317851346efdf03aa1317bc600138e871509b995e773cce
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 IGFBP3 MYBPC2

1.10e-031785135cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

DPP4 ENPP1 MYBPC2

1.10e-031785130667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLNA FLNC ENPP1

1.10e-031785138ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLNA FLNC ENPP1

1.10e-031785136c91331196696e0cf239d105f458e3230659fa38
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 TMEM45A BACE2

1.10e-03178513ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 TMEM45A BACE2

1.10e-0317851387b04753650e45f12299c8456fb980d6c0d5961c
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC IGFBP3 MYRF

1.10e-03178513bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CTNNAL1 DNAJB5 ONECUT3

1.10e-03178513c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNAL1 TMEM45A BACE2

1.10e-03178513ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FLNC COL8A2 ENPP1

1.10e-03178513cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellTCGA-Liver-Solid_Tissue_Normal|TCGA-Liver / Sample_Type by Project: Shred V9

PLSCR4 NAT2 IGFBP3

1.12e-031795137046f0a426e45fe1b41a25721ee1e33f6fc7f9e3
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IGFBP3 ENPP1 MYRF

1.12e-0317951398c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver|TCGA-Liver / Sample_Type by Project: Shred V9

PLSCR4 NAT2 IGFBP3

1.12e-031795130e22e840f43ca81a7543dcf33ec17a741cdf7f37
DrugC5-substituted pyrrolidine 31

DPP4 DPP9

4.92e-062512CID010339570
DrugSureCN3749646

DPP4 DPP9

1.47e-053512CID011530920
DrugSureCN3745540

DPP4 DPP9

1.47e-053512CID011974437
DrugSureCN3749947

DPP4 DPP9

1.47e-053512CID011974435
DrugABT-279

DPP4 DPP9

1.47e-053512CID016049769
DrugCyanopyrrolidine 38

DPP4 DPP9

1.47e-053512CID010932707
DrugCyanopyrrolidine 39

DPP4 DPP9

1.47e-053512CID011117606
DrugSureCN3748611

DPP4 DPP9

1.47e-053512CID011974325
DrugDiprolyl-alanine

DPP4 DPP9

1.47e-053512CID000193559
Drugglycylproline 4-nitroanilide

DPP4 DPP9

2.94e-054512ctd:C042892
DrugAC1NRATE

DPP4 DPP9 ENPP1 BACE2

3.60e-0583514CID005288086
Drugprodipine

DPP4 DPP9

4.90e-055512CID000065775
Drug1-N-methyl-5-thiotetrazole

USP13 IGFBP3

4.90e-055512ctd:C038625
Drugarginyl(PMC)-pyrrolidine-2-nitrile

DPP4 DPP9

4.90e-055512CID000487437
Drugalanylproline-4-nitroanilide

DPP4 DPP9

4.90e-055512ctd:C083013
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; HL60; HG-U133A

VPS13D CTNNAL1 TMEM135 YY1 PRRC2B

7.11e-051935151375_DN
DrugPrazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; HL60; HT_HG-U133A

VPS13D ARHGEF10 QTRT1 YY1 PRRC2B

7.11e-051935153098_DN
Drugcathepsin C substrate

DPP4 DPP9

7.34e-056512CID003508173
DrugNVP-DPP728

DPP4 DPP9

7.34e-056512CID009796290
DrugMK-251

DPP4 DPP9

7.34e-056512CID000176160
DrugCefoperazone

USP13 IGFBP3

7.34e-056512ctd:D002438
DrugII 19

DPP4 DPP9

7.34e-056512CID000040321
DrugPseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A

COL8A2 IGFBP3 TMEM45A ENPP1 QTRT1

7.65e-051965157184_UP
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; MCF7; HT_HG-U133A

FLNC VPS13D IGFBP3 TMEM45A DNAJB5

7.65e-051965151505_UP
DrugCompound 10

DPP9 SYNE1 BACE2

7.80e-0537513CID003749170
DrugDemecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A

IGFBP3 TMEM45A ARHGEF10 NOL10 QTRT1

7.84e-051975152773_UP
DrugGlibenclamide [10238-21-8]; Up 200; 8uM; MCF7; HT_HG-U133A

COL8A2 IGFBP3 ARHGEF10 NOL10 DNAJB5

8.22e-051995157202_UP
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; HL60; HT_HG-U133A

RIPK1 SYNE1 DTX4 SEC24B ANO10

8.42e-052005153078_DN
DrugEpostatin

DPP4 DPP9

1.03e-047512CID006449105
Drugo-Py

DPP4 DPP9

1.03e-047512CID009942336
DrugCID6451162

DPP4 DPP9

1.37e-048512CID006451162
Drugacronycine

ENPP1 SYNE1

1.37e-048512CID000345512
DrugP32/98

DPP4 DPP9

1.37e-048512CID006918464
Drugimidazolelactate

DPP4 DPP9

1.37e-048512CID000000793
DrugGly-D-Phe

DPP4 DPP9 BACE2

1.50e-0446513CID000092953
DrugNSC-334212

DPP4 DPP9

1.75e-049512CID000333414
DrugGly-pro-na

DPP4 DPP9

1.75e-049512CID000194319
DrugAppna

DPP4 DPP9

1.75e-049512CID006453929
DrugPhe-pro-ala

DPP4 DPP9

1.75e-049512CID000133668
DrugSureCN475872

DPP4 DPP9

1.75e-049512CID011163584
DrugNSC285223

ENPP1 SYNE1

2.19e-0410512CID000323607
DrugN-phenylphthalimide

DPP4 DPP9

2.19e-0410512CID000068215
DrugHxp

DPP4 DPP9

2.19e-0410512CID000449159
DrugX1043

DPP4 DPP9

2.19e-0410512CID011235728
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

7.77e-063482DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

7.77e-063482DOID:0111190 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

FLNA FLNC MYBPC2

6.64e-0548483DOID:423 (implicated_via_orthology)
Diseasetransitional cell carcinoma (is_implicated_in)

NAT2 IGFBP3

5.86e-0422482DOID:2671 (is_implicated_in)
DiseaseEpileptic encephalopathy

FLNA ALG13

1.09e-0330482C0543888

Protein segments in the cluster

PeptideGeneStartEntry
GYYLEMLIGTPPQKL

BACE2

91

Q9Y5Z0
NAKPNKVYMGPGQLY

ARHGEF10

736

O15013
MGKDYYKILGIPSGA

DNAJB5

1

O75953
KGRGYQKMPGGYVPE

ALG13

561

Q9NP73
GQKGYVPANYLGKMT

ARHGEF38

761

Q9NXL2
PGYGTMGKPIKLLAN

AGO3

21

Q9H9G7
YLVPGMTYSKGKIYP

CDSN

306

Q15517
YGVKTGTQPPGKMEY

DTX4

471

Q9Y2E6
LGVMVYGIKKYGPFV

ATP5PB

106

P24539
YSKILGPKPQGVYMG

MFSD8

441

Q8NHS3
KMIPGYPQAKLYPGK

ANO10

141

Q9NW15
MPKKGQPGYPSSAEY

BSN

3691

Q9UPA5
GGIHPVRYQPGKYPM

PLSCR4

76

Q9NRQ2
MAPGNYLIAIKYGGP

FLNC

2566

Q14315
EYKGMPGGRNLYKIQ

DPP4

421

P27487
GIFPDIYKMYNGSVP

ENPP1

331

P22413
NETPKMGIYYIPVLG

NOL10

331

Q9BSC4
IMYVGPRYGNPKEQK

OR2A7

256

Q96R45
YKEVMKQYGLGPNGG

GPN1

76

Q9HCN4
IMYVGPRYGNPKEQK

OR2A4

256

O95047
LGPKMYNAYGLITPE

KDM3A

1096

Q9Y4C1
GEKYGYLSLPKPMKN

CTNNAL1

531

Q9UBT7
LYGMIYKPHALQPGK

DPP9

621

Q86TI2
AYGPGIEPTGNMVKK

FLNA

286

P21333
AGYAPVKYIQPMQKG

COL8A2

36

P25067
TTMLGGYFYIPPVNK

NAT2

86

P11245
CPPKGNMPKGYVYLV

CPEB1

351

Q9BZB8
GLLLYLKTGQMYPVP

DNA2

331

P51530
QPSKMAKPFGYGYPT

SEC24B

451

O95487
VGHLYGPYGKELPAM

ONECUT3

181

O60422
DKYGQPLPGYTTKGK

IGFBP3

266

P17936
PKDKPRYLMGVGYAT

QTRT1

251

Q9BXR0
PTGPELDTSYKGYMK

SYNE1

8361

Q8NF91
GMDGTLYKIHPQYPK

HKDC1

411

Q2TB90
YEEMGIKPPKGVILY

PSMC1

211

P62191
GTAKKNGGTLYYMAP

RIPK1

181

Q13546
PGMKPYGYKECGKGL

ZNF182

201

P17025
MKSPREPGYKAEGKY

THRAP3

696

Q9Y2W1
KGYGLMKIDEPSPPY

PPP1R2B

61

Q6NXS1
KGVLMYGPPGTGKTL

PSMC3

221

P17980
YSEYMTGKKLPPGGI

YY1

251

P25490
MYFKGIEAGKVPYFP

TMEM135

361

Q86UB9
PEGYMALQSKGYPLP

PRRC2B

746

Q5JSZ5
LGVAYPKGMYDVGLP

UAP1

116

Q16222
LEYSEYMTGKKLPPG

ZFP42

141

Q96MM3
IYGLPTGEYPGLMKV

PIPOX

256

Q9P0Z9
IPGGPHLMLYDYKQG

TMEM45A

71

Q9NWC5
QESGTKLKPMYGPGY

USP13

321

Q92995
KLKPMYGPGYTGLKN

USP13

326

Q92995
FYVKGMPINGTLKPG

VPS13D

3196

Q5THJ4
PPMYDGGKPVTGYLV

MYBPC2

661

Q14324
VYIGMLGEPKYVKTP

MYRF

406

Q9Y2G1