Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein kinase A binding

EZR AKAP4 WASF3 ARFGEF2 ARFGEF1 RDX

4.79e-0858696GO:0051018
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

EZR WASF3 ARFGEF2 ARFGEF1

1.56e-0625694GO:0034237
GeneOntologyMolecularFunctioncytoskeletal protein binding

EZR MYH8 FAM161A POLB WASF3 ARFGEF2 ARFGEF1 RDX AFDN SPAG9 CCDC61 JMY MAPK8IP3 MSN

1.94e-0510996914GO:0008092
GeneOntologyMolecularFunctionDNA polymerase activity

POLB POLD1 TEP1

3.05e-0438693GO:0034061
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

RTEL1 POLD1 CDK5RAP1

5.74e-0447693GO:0051539
GeneOntologyMolecularFunctionsignaling receptor complex adaptor activity

CARD10 SPAG9 MAPK8IP3

8.63e-0454693GO:0030159
GeneOntologyMolecularFunctionMAP-kinase scaffold activity

SPAG9 MAPK8IP3

8.96e-0413692GO:0005078
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

ARFGEF2 ARFGEF1 HERC1 ARHGEF11 ARHGEF10L

1.22e-03231695GO:0005085
GeneOntologyMolecularFunctionactin binding

EZR MYH8 WASF3 RDX AFDN JMY MSN

1.31e-03479697GO:0003779
GeneOntologyMolecularFunctionArp2/3 complex binding

WASF3 JMY

1.37e-0316692GO:0071933
GeneOntologyMolecularFunctionJUN kinase binding

SPAG9 MAPK8IP3

1.55e-0317692GO:0008432
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH17

1.74e-0318692GO:0008569
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RASA1 ARFGEF2 ARFGEF1 ARHGAP39 HERC1 ARHGEF11 ARHGEF10L

1.81e-03507697GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RASA1 ARFGEF2 ARFGEF1 ARHGAP39 HERC1 ARHGEF11 ARHGEF10L

1.81e-03507697GO:0030695
GeneOntologyMolecularFunctionnucleotidyltransferase activity

POLB POLD1 TEP1 POLR3G

1.90e-03152694GO:0016779
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

RTEL1 POLB POLD1 CHD1 TEP1

2.12e-03262695GO:0140097
GeneOntologyMolecularFunctionGABA receptor binding

ERBB4 ARFGEF2

2.15e-0320692GO:0050811
GeneOntologyMolecularFunctioniron-sulfur cluster binding

RTEL1 POLD1 CDK5RAP1

2.50e-0378693GO:0051536
GeneOntologyMolecularFunctionGTPase activator activity

RASA1 ARFGEF1 ARHGAP39 ARHGEF11 ARHGEF10L

2.79e-03279695GO:0005096
GeneOntologyMolecularFunctionmetal cluster binding

RTEL1 POLD1 CDK5RAP1

2.98e-0383693GO:0051540
GeneOntologyMolecularFunctionmyosin binding

MYH8 ARFGEF2 ARFGEF1

3.19e-0385693GO:0017022
GeneOntologyMolecularFunctionDNA-directed DNA polymerase activity

POLB POLD1

3.35e-0325692GO:0003887
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH17

4.20e-0328692GO:0051959
GeneOntologyMolecularFunctionmicrotubule binding

EZR FAM161A POLB CCDC61 JMY

4.25e-03308695GO:0008017
GeneOntologyBiologicalProcesspositive regulation of early endosome to late endosome transport

EZR RDX MSN

2.71e-069673GO:2000643
GeneOntologyBiologicalProcessregulation of protein localization to early endosome

EZR RDX MSN

3.87e-0610673GO:1902965
GeneOntologyBiologicalProcesspositive regulation of protein localization to early endosome

EZR RDX MSN

3.87e-0610673GO:1902966
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

EZR RDX MSN

1.16e-0514673GO:1905668
GeneOntologyBiologicalProcessregulation of protein localization to endosome

EZR RDX MSN

1.45e-0515673GO:1905666
GeneOntologyBiologicalProcessprotein localization to early endosome

EZR RDX MSN

1.78e-0516673GO:1902946
GeneOntologyBiologicalProcessregulation of early endosome to late endosome transport

EZR RDX MSN

3.59e-0520673GO:2000641
GeneOntologyBiologicalProcessestablishment of endothelial barrier

EZR RDX AFDN MSN

3.78e-0558674GO:0061028
GeneOntologyBiologicalProcessregulation of cell morphogenesis

EZR RASA1 WASF3 RDX AFDN SPAG9 MSN

5.52e-05302677GO:0022604
GeneOntologyBiologicalProcessendothelial cell development

EZR RDX AFDN MSN

1.34e-0480674GO:0001885
GeneOntologyBiologicalProcessnucleotide-excision repair, DNA gap filling

POLB POLD1

1.55e-046672GO:0006297
GeneOntologyBiologicalProcessprotein localization to endosome

EZR RDX MSN

1.67e-0433673GO:0036010
GeneOntologyBiologicalProcessregulation of cell shape

EZR RASA1 WASF3 RDX MSN

1.68e-04159675GO:0008360
GeneOntologyBiologicalProcesspositive regulation of cardiac muscle cell proliferation

ERBB4 ZFPM2 CCND2

2.55e-0438673GO:0060045
GeneOntologyBiologicalProcessorganelle assembly

TUBB1 EZR AKAP4 UBQLN2 FAM161A DNAH17 SQLE ATG2B RDX CCDC61 CCDC63 MSN

2.69e-0411386712GO:0070925
GeneOntologyBiologicalProcesscell morphogenesis

KIAA0319 TUBB1 EZR B4GAT1 RASA1 WASF3 ETV4 RDX AFDN SPAG9 MAPK8IP3 MSN

4.16e-0411946712GO:0000902
GeneOntologyBiologicalProcessregulation of developmental growth

KIAA0319 EZR ERBB4 AFDN SPAG9 ZFPM2 CCND2

4.25e-04421677GO:0048638
GeneOntologyCellularComponentcell tip

EZR RDX MSN

2.26e-0517693GO:0051286
GeneOntologyCellularComponentcell pole

EZR RDX MSN

3.77e-0520693GO:0060187
DomainERM_C_dom

EZR RDX MSN

1.61e-074653IPR011259
DomainERM

EZR RDX MSN

1.61e-074653PF00769
DomainERM

EZR RDX MSN

1.61e-074653IPR011174
DomainMoesin_tail

EZR RDX MSN

1.39e-067653IPR008954
DomainWD40_repeat_dom

TAF1C SMU1 NOL11 SPAG9 HERC1 TEP1 ARHGEF10L MAPK8IP3

8.56e-06297658IPR017986
DomainJIP_LZII

SPAG9 MAPK8IP3

1.19e-052652IPR032486
DomainJIP_LZII

SPAG9 MAPK8IP3

1.19e-052652PF16471
Domain-

TAF1C SMU1 NOL11 SPAG9 HERC1 TEP1 ARHGEF10L MAPK8IP3

1.96e-053336582.130.10.10
DomainWD40/YVTN_repeat-like_dom

TAF1C SMU1 NOL11 SPAG9 HERC1 TEP1 ARHGEF10L MAPK8IP3

2.04e-05335658IPR015943
DomainUbiquitin-rel_dom

EZR UBQLN2 USP24 RDX AFDN MSN

4.30e-05184656IPR029071
DomainEz/rad/moesin-like

EZR RDX MSN

5.12e-0521653IPR000798
DomainDUF1981

ARFGEF2 ARFGEF1

7.12e-054652PF09324
DomainJnk-SapK_ap_N

SPAG9 MAPK8IP3

7.12e-054652PF09744
DomainJNK/Rab-associated_protein-1_N

SPAG9 MAPK8IP3

7.12e-054652IPR019143
DomainSec7_N

ARFGEF2 ARFGEF1

7.12e-054652IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

7.12e-054652PF12783
DomainDCB_dom

ARFGEF2 ARFGEF1

7.12e-054652IPR032629
DomainDCB

ARFGEF2 ARFGEF1

7.12e-054652PF16213
DomainSec7_C

ARFGEF2 ARFGEF1

7.12e-054652IPR015403
DomainFERM_CS

EZR RDX MSN

7.73e-0524653IPR019747
DomainFERM_C

EZR RDX MSN

9.88e-0526653PF09380
DomainFERM_C

EZR RDX MSN

1.11e-0427653SM01196
DomainFERM_PH-like_C

EZR RDX MSN

1.11e-0427653IPR018980
DomainRH2

SPAG9 MAPK8IP3

1.18e-045652PS51777
DomainRH1

SPAG9 MAPK8IP3

1.18e-045652PS51776
DomainFERM_N

EZR RDX MSN

2.04e-0433653PF09379
DomainFERM_N

EZR RDX MSN

2.04e-0433653IPR018979
DomainFERM_M

EZR RDX MSN

5.49e-0446653PF00373
Domain-

EZR RDX MSN

6.61e-04496531.20.80.10
DomainFERM_central

EZR RDX MSN

6.61e-0449653IPR019748
DomainFERM_domain

EZR RDX MSN

6.61e-0449653IPR000299
DomainFERM_1

EZR RDX MSN

7.02e-0450653PS00660
DomainFERM_2

EZR RDX MSN

7.02e-0450653PS00661
DomainFERM_3

EZR RDX MSN

7.02e-0450653PS50057
DomainBand_41_domain

EZR RDX MSN

7.02e-0450653IPR019749
DomainB41

EZR RDX MSN

7.02e-0450653SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

EZR RDX MSN

7.02e-0450653IPR014352
DomainWH2

WASF3 JMY

1.06e-0314652SM00246
Domain-

ARFGEF2 ARFGEF1

1.22e-03156521.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1

1.22e-0315652PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

1.22e-0315652IPR023394
DomainSec7

ARFGEF2 ARFGEF1

1.39e-0316652SM00222
DomainSEC7

ARFGEF2 ARFGEF1

1.39e-0316652PS50190
DomainSec7_dom

ARFGEF2 ARFGEF1

1.39e-0316652IPR000904
Domain-

EZR RASA1 RDX ARHGEF11 ARHGEF10L MSN

2.36e-033916562.30.29.30
DomainWH2_dom

WASF3 JMY

2.40e-0321652IPR003124
DomainWH2

WASF3 JMY

3.13e-0324652PS51082
DomainPH_dom-like

EZR RASA1 RDX ARHGEF11 ARHGEF10L MSN

3.61e-03426656IPR011993
DomainHECT

WWP2 HERC1

3.96e-0327652PF00632
DomainHECTc

WWP2 HERC1

3.96e-0327652SM00119
DomainHECT_dom

WWP2 HERC1

3.96e-0327652IPR000569
DomainHECT

WWP2 HERC1

3.96e-0327652PS50237
DomainDNA/RNA_helicase_DEAH_CS

RTEL1 CHD1

6.59e-0335652IPR002464
PathwayWP_PTDINS45P2_IN_CYTOKINESIS_PATHWAY

EZR RDX MSN

1.65e-0512613M45558
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

TUBB1 EZR RDX MSN

1.88e-0537614MM15102
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

TUBB1 EZR RDX MSN

5.81e-0549614M891
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

TUBB1 EZR COL6A3 RASA1 RDX ARHGEF11 MSN

1.28e-04261617MM15676
PathwayREACTOME_L1CAM_INTERACTIONS

TUBB1 EZR RDX MSN

2.10e-0468614MM14968
Pubmed

Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.

EZR CYP1A1 RDX MSN

7.51e-1157049464455
Pubmed

The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.

EZR RDX MSN

7.81e-0937038479753
Pubmed

Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.

EZR RDX MSN

7.81e-09370318261459
Pubmed

Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.

EZR RDX MSN

7.81e-09370321659656
Pubmed

Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.

EZR RDX MSN

7.81e-09370319064715
Pubmed

Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.

EZR RDX MSN

7.81e-09370331843195
Pubmed

Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.

EZR RDX MSN

7.81e-09370321864676
Pubmed

Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.

EZR RDX MSN

7.81e-09370314613898
Pubmed

Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.

EZR RDX MSN

7.81e-09370321278069
Pubmed

Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.

EZR RDX MSN

7.81e-09370326555866
Pubmed

Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.

EZR RDX MSN

7.81e-09370323703860
Pubmed

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.

EZR RDX MSN

7.81e-09370316889625
Pubmed

Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.

EZR RDX MSN

7.81e-09370315149851
Pubmed

Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.

EZR RDX MSN

7.81e-09370321837648
Pubmed

ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.

EZR RDX MSN

7.81e-09370321352885
Pubmed

Ezrin and moesin function together to promote T cell activation.

EZR RDX MSN

7.81e-09370319124745
Pubmed

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

EZR RDX MSN

7.81e-0937031429901
Pubmed

ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.

EZR RDX MSN

7.81e-09370332098334
Pubmed

Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.

EZR RDX MSN

7.81e-09370318295815
Pubmed

Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.

EZR RDX MSN

7.81e-09370312360288
Pubmed

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

EZR RDX MSN

7.81e-09370322132106
Pubmed

Dynamics and function of ERM proteins during cytokinesis in human cells.

EZR RDX MSN

7.81e-09370328889652
Pubmed

Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.

EZR RDX MSN

7.81e-09370323116763
Pubmed

Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.

EZR RDX MSN

7.81e-09370321451358
Pubmed

Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.

EZR RDX MSN

7.81e-09370319321616
Pubmed

Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.

EZR RDX MSN

7.81e-09370329906485
Pubmed

Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.

EZR RDX MSN

7.81e-09370320679347
Pubmed

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.

EZR RDX MSN

7.81e-09370312385025
Pubmed

Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?

EZR RDX MSN

7.81e-09370325286001
Pubmed

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

EZR RDX MSN

7.81e-09370317977945
Pubmed

Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.

EZR RDX MSN

7.81e-09370315252013
Pubmed

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.

EZR RDX MSN

7.81e-09370332160548
Pubmed

The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.

EZR RDX MSN

7.81e-09370312734202
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

EZR ATG2B SMU1 ARFGEF2 ARFGEF1 RDX AFDN MSN

1.27e-0821570835973513
Pubmed

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.

EZR RDX MSN

3.12e-08470312070130
Pubmed

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.

EZR RDX MSN

3.12e-08470327793041
Pubmed

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

EZR RDX MSN

3.12e-08470315096511
Pubmed

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

EZR RDX MSN

3.12e-08470319890007
Pubmed

The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.

EZR RDX MSN

3.12e-08470328302370
Pubmed

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.

EZR RDX MSN

3.12e-08470322685202
Pubmed

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.

EZR RDX MSN

3.12e-08470321289089
Pubmed

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.

EZR RDX MSN

3.12e-08470317237445
Pubmed

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.

EZR RDX MSN

3.12e-08470321148287
Pubmed

Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.

EZR RDX MSN

3.12e-08470318941185
Pubmed

Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.

EZR RDX MSN

3.12e-08470315178693
Pubmed

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.

EZR RDX MSN

3.12e-08470320660156
Pubmed

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.

EZR RDX MSN

3.12e-08470319129194
Pubmed

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.

EZR RDX MSN

3.12e-08470315818415
Pubmed

Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.

EZR RDX MSN

3.12e-08470331018575
Pubmed

Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.

EZR RDX MSN

3.12e-08470324760896
Pubmed

Proteomic profiling in pancreatic cancer with and without lymph node metastasis.

EZR RDX MSN

3.12e-08470319152423
Pubmed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

EZR RDX MSN

3.12e-08470319255442
Pubmed

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.

EZR RDX MSN

3.12e-0847039890997
Pubmed

Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

EZR RDX MSN

3.12e-08470320855527
Pubmed

Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.

EZR RDX MSN

7.79e-08570321278261
Pubmed

Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.

EZR RDX MSN

7.79e-08570322891241
Pubmed

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.

EZR RDX MSN

7.79e-08570310806479
Pubmed

Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.

EZR RDX MSN

7.79e-08570323019340
Pubmed

Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.

EZR RDX MSN

7.79e-08570323326330
Pubmed

Regulation of NK cell trafficking by CD81.

EZR RDX MSN

7.79e-08570319830727
Pubmed

Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).

EZR RDX MSN

7.79e-08570325575591
Pubmed

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

EZR RDX MSN

7.79e-08570323063725
Pubmed

A novel role for BRCA1 in regulating breast cancer cell spreading and motility.

EZR RDX MSN

7.79e-08570321282464
Pubmed

Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.

EZR RDX MSN

1.55e-07670317349711
Pubmed

Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.

EZR RDX MSN

1.55e-07670326209696
Pubmed

Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.

EZR RDX MSN

1.55e-07670317515952
Pubmed

Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.

EZR RDX MSN

1.55e-07670323229862
Pubmed

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.

EZR RDX MSN

1.55e-0767039472040
Pubmed

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.

EZR RDX MSN

2.72e-07770323264465
Pubmed

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.

EZR RDX MSN

2.72e-07770322291017
Pubmed

VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner.

EZR RDX MSN

4.34e-07870324788249
Pubmed

Finding the Unicorn, a New Mouse Model of Midfacial Clefting.

EZR RDX MSN

6.50e-07970331940751
Pubmed

Radixin regulates cell migration and cell-cell adhesion through Rac1.

EZR RDX MSN

6.50e-07970322467863
Pubmed

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath.

EZR RDX MSN

1.70e-061270318579745
Pubmed

Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.

EZR RDX MSN

1.70e-061270329361573
Pubmed

Embryo-uterine interaction coordinates mouse embryogenesis during implantation.

EZR RDX MSN

2.20e-061370337522872
Pubmed

A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells.

EZR RDX MSN

2.20e-061370324135232
Pubmed

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.

EZR RDX MSN

2.80e-061470327641493
Pubmed

Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif.

SPAG9 MAPK8IP3

3.99e-06270231690808
Pubmed

Expression of ezrin and moesin related to invasion, metastasis and prognosis of laryngeal squamous cell carcinoma.

EZR MSN

3.99e-06270225299115
Pubmed

Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin.

EZR MSN

3.99e-0627029213396
Pubmed

Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.

EZR MSN

3.99e-06270212111362
Pubmed

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.

EZR MSN

3.99e-0627027579708
Pubmed

Ezrin has properties to self-associate at the plasma membrane.

EZR MSN

3.99e-0627027844168
Pubmed

Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology.

EZR RDX

3.99e-06270231382374
Pubmed

Expression of ezrin and moesin in primary breast carcinoma and matched lymph node metastases.

EZR MSN

3.99e-06270228624994
Pubmed

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.

SPAG9 MAPK8IP3

3.99e-06270233788575
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

3.99e-06270223918382
Pubmed

Loss of a negative feedback loop involving pea3 and cyclin d2 is required for pea3-induced migration in transformed mammary epithelial cells.

ETV4 CCND2

3.99e-06270223989931
Pubmed

Immunohistochemical assessment of ezrin and moesin in colorectal carcinoma.

EZR MSN

3.99e-06270227042764
Pubmed

Emerging role for ERM proteins in cell adhesion and migration.

EZR RDX

3.99e-06270221343695
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

3.99e-06270217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

3.99e-06270210716990
Pubmed

Coordinated processing of 3' slipped (CAG)n/(CTG)n hairpins by DNA polymerases β and δ preferentially induces repeat expansions.

POLB POLD1

3.99e-06270223585564
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

3.99e-06270218203920
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

3.99e-06270210212200
Pubmed

Radixin is a novel member of the band 4.1 family.

EZR RDX

3.99e-0627021955455
Pubmed

Mapping of ezrin dimerization using yeast two-hybrid screening.

EZR RDX

3.99e-0627029501018
Pubmed

Moesin: a member of the protein 4.1-talin-ezrin family of proteins.

EZR MSN

3.99e-0627021924289
Pubmed

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins.

EZR MSN

3.99e-0627028248180
CytobandEnsembl 112 genes in cytogenetic band chr5q14

RASA1 JMY POLR3G

1.20e-03136703chr5q14
Cytoband11q23

APOA5 RDX

1.40e-033670211q23
CytobandEnsembl 112 genes in cytogenetic band chr2q34

ERBB4 UNC80

2.17e-0345702chr2q34
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

EZR AKAP4 ARFGEF2

6.91e-0529503396
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EZR RDX MSN

3.56e-04505031293
GeneFamilyWiskott-Aldrich Syndrome protein family

WASF3 JMY

8.77e-041650214
GeneFamilyDyneins, axonemal

DNAH10 DNAH17

9.93e-0417502536
GeneFamilyDNA polymerases

POLB POLD1

1.83e-0323502535
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE

TUBB1 EZR PTPN2 NAE1 NOL11 CHD1 JMY CCND2

5.02e-06363698M41103
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP

EZR DNAH17 ATG2B USP24 ARFGEF1 CDK5RAP1

1.47e-05200696M9336
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TUBB1 FAM161A GAL3ST2 UNC80 ZFPM2

4.51e-06159685fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TUBB1 FAM161A GAL3ST2 UNC80 ZFPM2

4.51e-06159685aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TUBB1 FAM161A GAL3ST2 UNC80 ZFPM2

4.51e-061596858bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CCDC60 POLD1 ATG2B SMU1 RDX

6.99e-06174685a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CCDC60 POLD1 ATG2B SMU1 RDX

7.19e-0617568578a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 COL6A3 LMCD1 UNC80 ZFPM2

9.91e-06187685c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ANO4 COL6A3 LMCD1 UNC80 ZFPM2

1.04e-0518968544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 RASA1 AFDN CCND2 MSN

1.07e-05190685d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR ARFGEF2 CHD1 HERC1 MAPK8IP3

1.10e-051916851ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 FAM161A ZFPM2

1.34e-05199685e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 FAM161A ZFPM2

1.37e-05200685c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B MYH8 ERBB4 UNC80

7.18e-0514568496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CCDC60 DNAH10 POLD1 WASF3

8.62e-051526845ce8920aedd39a4daf7082153b5e213707c14227
ToppCellcontrol-B_cell|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TUBB1 AFDN UNC80 SLC44A3

9.77e-051576841269b55f2ef6a493f6116b131cc5cc7b8897d63e
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANO4 CACNA1B COL6A3 LMCD1

9.77e-05157684b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B MYH8 DNAH10 UNC80

1.05e-04160684c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B MYH8 DNAH10 UNC80

1.05e-0416068425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMCD1 CYP27A1 KLHL14 CCND2

1.08e-04161684b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B ERBB4 DNAH10 UNC80

1.10e-04162684bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

TUBB1 EZR ARHGAP39 KLHL14

1.10e-04162684ae292318d339305932457bb0e91430594f7a3dfa
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 DNAH10 ETV4 GAL3ST2

1.24e-04167684cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN2 COL6A3 KLHL14 CCND2

1.27e-04168684f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB4 DNAH10 ETV4 GAL3ST2

1.30e-0416968430141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO4 COL6A3 LMCD1 ZFPM2

1.42e-041736841f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B SQLE WASF3 UNC80

1.48e-041756848362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B SQLE WASF3 UNC80

1.48e-041756848b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN2 COL6A3 KLHL14 CCND2

1.48e-041756846a093c74a6f3daeff07759d6eec542fc5c709149
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 APOA5 LMCD1 MSN

1.52e-04176684eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB1 CACNA1B DNAH10 HID1

1.55e-041776848abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 COL6A3 LMCD1 ZFPM2

1.76e-0418368412daaea821e49bc94a01e2496331e92a80d27339
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

CTNNBIP1 WASF3 AFDN SLC44A3

1.80e-04184684561592edc3083fad41b91811151b442207c65dd9
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

ANO4 COL6A3 LMCD1 ZFPM2

1.80e-0418468486a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 CTNNBIP1 LMCD1 AFDN

1.83e-04185684c3105978d971da7d0fad1a717ee29afee5ed6357
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 COL6A3 LMCD1 ZFPM2

1.83e-041856846712512100ccef456d2e2bd201d0987986c92ac9
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 CTNNBIP1 LMCD1 AFDN

1.83e-041856844cfef50aeed5b3000ce5e864a41c13740b8267b1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 COL6A3 LMCD1 ZFPM2

1.83e-041856843b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 CTNNBIP1 LMCD1 AFDN

1.83e-0418568409256c6f42f59b7eb89160b2ea706172a5b743be
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNBIP1 SQLE ETV4 HID1

1.91e-04187684ab109aa51beae3df474c15002e70361f328cadad
ToppCellfacs-Large_Intestine-Distal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNBIP1 SQLE ETV4 HID1

1.91e-04187684a4c408fc941d2e8a811a26aa916c0b3e3341163a
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ANO4 COL6A3 LMCD1 ZFPM2

1.91e-04187684bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP24 ARFGEF1 CHD1 HERC1

1.95e-04188684ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDX CHD1 SPAG9 CCND2

1.95e-04188684d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 COL6A3 LMCD1 ZFPM2

1.99e-041896847ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANO4 CACNA1B COL6A3 LMCD1

2.03e-04190684d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A3 LMCD1 ETV4 CCND2

2.03e-041906842ab604d35456beba71c25511e0f819000e6642d2
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

ANO4 COL6A3 LMCD1 UNC80

2.07e-0419168486ce98d2c90c196474b06869de888cf5d1eed196
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 ERBB4 B4GAT1 RASA1

2.07e-04191684764c3a8829ae1253a0790744138266e81fc075ec
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 COL6A3 LMCD1 UNC80

2.11e-0419268472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

COL6A3 ARFGEF1 CHD1 HERC1

2.11e-0419268447646d7e4990be85072987f92bf18d52f8da752e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ANO4 COL6A3 LMCD1 ETV4

2.11e-041926844c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHD1 HERC1 KLHL14 MAPK8IP3

2.11e-04192684aee6522d25e012231cdb905ce047295cb64d6e82
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANO4 CACNA1B LMCD1 ETV4

2.11e-04192684c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Early_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYP1A1 ETV4 RDX HID1

2.11e-041926844986ef70a665fdfa1df86f7f8a15117487eae159
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EZR ERBB4 AFDN SLC44A3

2.16e-04193684f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 AFDN ARHGEF10L SLC44A3

2.16e-041936843866667dd221612589ae50f5c52f73a183a49ce6
ToppCellfacs-Tongue-nan-3m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 SQLE AFDN ARHGEF10L

2.16e-0419368433437fdb417d78463caee14a9f0e094da1733829
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EZR ERBB4 AFDN SLC44A3

2.16e-0419368442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNBIP1 CHD1 SPAG9 CCND2

2.20e-04194684e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 UBQLN2 LMCD1 HID1

2.20e-04194684e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 UBQLN2 LMCD1 HID1

2.20e-041946844b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV4 ARHGEF10L SLC44A3 CCND2

2.24e-04195684b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH17 CHD1 SPAG9 JMY

2.29e-0419668401cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LMCD1 AFDN CARD10 HID1

2.33e-04197684b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANO4 COL6A3 LMCD1 ZFPM2

2.33e-041976846d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV4 ARHGEF10L SLC44A3 CCND2

2.38e-04198684a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO4 ERBB4 B4GAT1 UNC80

2.38e-0419868402d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV4 ARHGEF10L SLC44A3 CCND2

2.38e-04198684e8bfae3888b2406b5629b576cb02913b3297337e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.42e-0419968438cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 HID1 MUC7 UNC80

2.47e-04200684e9908b6cba21a59023cf8d0f98fbd1d1f7de6b44
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1B ERBB4 AFDN KLHL14

2.47e-04200684bad32a95b759fad509401b07bc96a56687c2a592
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.47e-042006849d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.47e-0420068487827041663013f5e7273168dc8709d69840e7ce
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 MUC7 UNC80 ARHGEF10L

2.47e-042006847c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.47e-042006848988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.47e-0420068408bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ANO4 COL6A3 LMCD1 ZFPM2

2.47e-0420068402cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellCOVID-19|World / Disease, condition lineage and cell class

EZR CHD1 SPAG9 MSN

2.47e-042006847dec470c379cd89f05a0f37c8628b21f136e52f0
DrugXylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; PC3; HT_HG-U133A

CYP1A1 ACOX1 ATG2B USP24 SPAG9 ARHGEF11 POLR3G

2.31e-061986972107_DN
DrugDichlorodiphenyl Dichloroethylene

CACNA1B CYP1A1 ERBB4 ACOX1 CYP27A1 ARFGEF2 RDX CARD10

3.62e-06302698ctd:D003633
Diseaseprostate cancer (is_implicated_in)

CYP1A1 RTEL1 CHD1 CCND2

1.48e-04117674DOID:10283 (is_implicated_in)
Diseaseplatelet component distribution width

TUBB1 CYP1A1 APOA5 CTNNBIP1 WASF3 HERC1 JMY ZFPM2

3.05e-04755678EFO_0007984
Diseasecoronary artery disease

KIAA0319 CYP1A1 COL6A3 ERBB4 DNAH10 APOA5 WASF3 ARFGEF2 ZFPM2 MAPK8IP3

3.45e-0411946710EFO_0001645
DiseaseS-adenosylhomocysteine measurement

ANO4 CACNA1B

6.76e-0417672EFO_0010531
Diseasehepatocellular carcinoma (is_implicated_in)

ERBB4 SPAG9 TEP1 CCND2

7.77e-04181674DOID:684 (is_implicated_in)
Diseaseexercise test

CCDC60 RDX

9.40e-0420672EFO_0004328
Diseasedescending aortic diameter

COL6A3 LMCD1 WWP2

1.07e-0388673EFO_0021788
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH10 APOA5 JMY CCND2

1.25e-03206674EFO_0004612, EFO_0020947
Diseasestomach carcinoma (is_marker_for)

ERBB4 CCND2

1.36e-0324672DOID:5517 (is_marker_for)
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

DNAH10 APOA5 MIDEAS

1.88e-03107673EFO_0004614, EFO_0004615
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

DNAH10 APOA5 CCND2

2.08e-03111673EFO_0004530, EFO_0008595
Diseaseresting heart rate, chronic obstructive pulmonary disease

HERC1 ZFPM2

2.12e-0330672EFO_0000341, EFO_0004351

Protein segments in the cluster

PeptideGeneStartEntry
MVKPMIRVEQQPDYR

AFDN

571

P55196
QIAKGMMYLEERRLV

ERBB4

826

Q15303
RLKDENYMIAMRLAQ

CARD10

201

Q9BWT7
KRILQDYRNPLMEME

ARHGEF10L

336

Q9HCE6
ARLKALQEYMNRLDM

CCDC61

496

Q9Y6R9
RRMPMNKNELVQLYQ

B4GAT1

266

O43505
DYLMNRPQNLRLEMT

AKAP4

166

Q5JQC9
QRRLLYNLEMEQMAK

ARFGEF1

906

Q9Y6D6
QRRLLYNLEMEQMAK

ARFGEF2

851

Q9Y6D5
YQRMKKENLMPREEL

ARHGEF11

761

O15085
RQQLKPYTMDLMEQV

APOA5

126

Q6Q788
AEQMNVRMPFRRKIY

ANO4

176

Q32M45
AYKRLVRMNMPISNE

CACNA1B

1771

Q00975
QKELEEIYMLPRMRN

CHD1

1061

O14646
EIYMLPRMRNCAKQI

CHD1

1066

O14646
RPMQQEDEYRIQMEL

ATG2B

356

Q96BY7
PLYMNLQKLLEMVRE

CCDC60

291

Q8IWA6
MERRMKAGYLDQQVP

ETV4

1

P43268
LMNPMIYTLRNQEVK

OR4N4C

281

A0A096LPK9
LRVRARYSMEKIMPE

RASA1

706

P20936
ALQEVMGMQRERYPE

ARHGAP39

891

Q9C0H5
MYLVMNPRVQRKIQE

CYP1A1

331

P04798
MRKYRMGLIQTPDQL

PTPN2

251

P17706
VLMERNQYKERLMEL

SPAG9

511

O60271
VVMMPEAKRLLINLY

NOL11

661

Q9H8H0
YMRRRKPDTIEVQQM

RDX

291

P35241
CVQKDIQPYMRRMVA

CCND2

46

P30279
VLMERNQYKERLMEL

MAPK8IP3

531

Q9UPT6
QYLLQPFRDMRELAM

JMY

381

Q8N9B5
RKRRKMYEMCLPEQE

ZFPM2

736

Q8WW38
RAFLERLPMMLQEQY

HERC1

3851

Q15751
RGFLMRVEYQKMLQR

MYH8

796

P13535
LMNPMIYTLRNQEVK

OR4N4

281

Q8N0Y3
YMRRRKPDTIEVQQM

MSN

291

P26038
IRIYKRNRMIMTNPI

LMCD1

91

Q9NZU5
LYMKNLLNRIIDDMV

MUC7

361

Q8TAX7
CQRLVMPELQYMARL

GAL3ST2

366

Q9H3Q3
RIPRENMLMKYAQVK

ACOX1

246

Q15067
ETRMQYAPDLMKRLR

KLHL14

251

Q9P2G3
MNRSEKNYMELRLLL

CCDC63

86

Q8NA47
LIPRLAKDRMNYKMD

DNAH17

941

Q9UFH2
YQPEMLEKFRNMRSQ

COL6A3

1906

P12111
QVMRQEGKYPVRNDM

CYP27A1

116

Q02318
KYRNPQREKEMMQLY

FAM172A

246

Q8WUF8
VDIRGEMPRNLREYM

SQLE

346

Q14534
EMPRNLREYMVEKIY

SQLE

351

Q14534
DRYVRPMMPQKVQLE

MIDEAS

176

Q6PJG2
PRIIVMYMQNALKEQ

SLC44A3

451

Q8N4M1
YMRRRKPDTIEVQQM

EZR

291

P15311
PRKNRMMTYAKELIN

FAM161A

186

Q3B820
YNKDERMIPLMERIA

DNAH10

381

Q8IVF4
FEKRIPREEMLQMQD

POLB

146

P06746
QMDMLQVLLREYKLR

POLD1

456

P28340
RMDPRVVLKMQFLDE

RTEL1

651

Q9NZ71
MPRYELALILKAMQR

MRPS6

1

P82932
QRQMLRDYMAKLPPQ

TAF1C

811

Q15572
PNYIHDMNRMELLKL

HID1

196

Q8IV36
LMNKIREEYPDRIMN

TUBB1

151

Q9H4B7
PRLALMYRMQVANID

SPG7

206

Q9UQ90
PEEMYIQQKVRVLLM

CTNNBIP1

11

Q9NSA3
MMDELLGRQRKVYLE

CDK5RAP1

91

Q96SZ6
QIMNMKPYDLRRRLY

WWP2

531

O00308
NRQDELMYMLRKLLL

UNC80

1901

Q8N2C7
RQQLRMAMRIPVLYE

TEP1

616

Q99973
MAMRIPVLYEQLKRE

TEP1

621

Q99973
DPMIMLKQTQPERYI

SMU1

101

Q2TAY7
PERLNAYEREVMVNM

SMRP1

151

Q8NCR6
NMMAYDKELRPDNRL

WASF3

206

Q9UPY6
MEAYRMKRQRPDDPM

SLU7

566

O95391
KQELRETMKRMPYFI

POLR3G

61

O15318
KMPARIYQMVRDENL

USP24

2111

Q9UPU5
NALRRMYTDIQEPML

UBQLN2

266

Q9UHD9
MDNPDNEIVLYLMLR

NAE1

416

Q13564
MDEQERMELRPKYGI

KIAA0319

1001

Q5VV43
VRYESELQMPDIMRL

NAA30

216

Q147X3