Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

HIPK3 HDAC9 ATN1 MAP1A BAZ2A MAPT TLE2 FBXO42 SH2D3C TRIM24 THRAP3 CNOT2

2.37e-0411606312GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

HIPK3 HDAC9 ATN1 MAP1A BAZ2A MAPT TLE2 FBXO42 SH2D3C TRIM24 AHDC1 THRAP3 CNOT2

2.65e-0413566313GO:0060090
GeneOntologyCellularComponentnuclear speck

LIMK1 BAZ2A MAPT YLPM1 DACH1 FOXO4 THRAP3 NXF1

3.91e-05431628GO:0016607
GeneOntologyCellularComponentnuclear body

HIPK3 LIMK1 BAZ2A MAPT TLE2 YLPM1 DACH1 FOXO4 THRAP3 NXF1 ZIC2

6.20e-059036211GO:0016604
DomainRASGEF_CAT

RAPGEF6 SH2D3C RAPGEF2

1.09e-0429603PS50009
DomainRasGEF

RAPGEF6 SH2D3C RAPGEF2

1.20e-0430603PF00617
Domain-

RAPGEF6 SH2D3C RAPGEF2

1.20e-04306031.10.840.10
DomainRas_GEF_dom

RAPGEF6 SH2D3C RAPGEF2

1.20e-0430603IPR023578
DomainRASGEF_cat_dom

RAPGEF6 SH2D3C RAPGEF2

1.20e-0430603IPR001895
DomainRasGEF

RAPGEF6 SH2D3C RAPGEF2

1.20e-0430603SM00147
DomainSer/Thr_kinase_AS

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

9.82e-04357606IPR008271
DomainPROTEIN_KINASE_ST

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

1.05e-03362606PS00108
DomainPDZ

LIMK1 RAPGEF6 RAPGEF2 TIAM2

1.09e-03141604PF00595
DomainPDZ

LIMK1 RAPGEF6 RAPGEF2 TIAM2

1.31e-03148604SM00228
DomainProtein_kinase_ATP_BS

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

1.33e-03379606IPR017441
DomainPkinase

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

1.37e-03381606PF00069
Domain-

LIMK1 RAPGEF6 RAPGEF2 TIAM2

1.37e-031506042.30.42.10
DomainPDZ

LIMK1 RAPGEF6 RAPGEF2 TIAM2

1.41e-03151604PS50106
DomainPDZ

LIMK1 RAPGEF6 RAPGEF2 TIAM2

1.44e-03152604IPR001478
Domain-

LIMK1 TRIP6 ZNF185

1.48e-03706032.10.110.10
DomainZnf_LIM

LIMK1 TRIP6 ZNF185

1.54e-0371603IPR001781
DomainLIM_DOMAIN_1

LIMK1 TRIP6 ZNF185

1.54e-0371603PS00478
DomainLIM_DOMAIN_2

LIMK1 TRIP6 ZNF185

1.54e-0371603PS50023
DomainLIM

LIMK1 TRIP6 ZNF185

1.54e-0371603SM00132
DomainRasGEFN

RAPGEF6 RAPGEF2

1.86e-0320602SM00229
DomainRasGEF_N

RAPGEF6 RAPGEF2

2.05e-0321602PF00618
DomainRas-like_Gua-exchang_fac_N

RAPGEF6 RAPGEF2

2.25e-0322602IPR000651
DomainRASGEF_NTER

RAPGEF6 RAPGEF2

2.25e-0322602PS50212
DomainBromodomain_CS

BAZ2A TRIM24

3.14e-0326602IPR018359
DomainAT_hook

BAZ2A AHDC1

3.38e-0327602SM00384
DomainAT_hook_DNA-bd_motif

BAZ2A AHDC1

3.38e-0327602IPR017956
DomainPROTEIN_KINASE_ATP

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

3.48e-03459606PS00107
DomainRA

RAPGEF6 RAPGEF2

4.44e-0331602SM00314
DomainProt_kinase_dom

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

4.73e-03489606IPR000719
DomainPROTEIN_KINASE_DOM

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

4.92e-03493606PS50011
DomaincNMP

RAPGEF6 RAPGEF2

5.33e-0334602SM00100
DomaincNMP_binding

RAPGEF6 RAPGEF2

5.33e-0334602PF00027
DomaincNMP-bd_dom

RAPGEF6 RAPGEF2

5.64e-0335602IPR000595
DomainCNMP_BINDING_3

RAPGEF6 RAPGEF2

5.64e-0335602PS50042
DomainS_TKc

HIPK3 KALRN WEE1 CDK14 MAP3K6

5.87e-03359605SM00220
DomainRA

RAPGEF6 RAPGEF2

5.96e-0336602PF00788
DomainBROMODOMAIN_1

BAZ2A TRIM24

6.29e-0337602PS00633
DomainRA

RAPGEF6 RAPGEF2

6.29e-0337602PS50200
DomaincNMP-bd-like

RAPGEF6 RAPGEF2

6.62e-0338602IPR018490
DomainBromodomain

BAZ2A TRIM24

6.62e-0338602PF00439
DomainRA_dom

RAPGEF6 RAPGEF2

7.32e-0340602IPR000159
DomainBROMODOMAIN_2

BAZ2A TRIM24

7.68e-0341602PS50014
DomainKinase-like_dom

HIPK3 LIMK1 KALRN WEE1 CDK14 MAP3K6

7.73e-03542606IPR011009
DomainBROMO

BAZ2A TRIM24

8.05e-0342602SM00297
DomainBromodomain

BAZ2A TRIM24

8.05e-0342602IPR001487
Domain-

BAZ2A TRIM24

8.05e-03426021.20.920.10
DomainTF_fork_head_CS_2

FOXD2 FOXO4

9.59e-0346602IPR030456
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCP110 LIMK1 RAPGEF6 TRIP6 MAPT WEE1 KIAA0232 KIAA1217 COBLL1 CAMSAP3 NAV1 CC2D1A FOXO4 RAPGEF2 CDK14 MAP3K6

2.15e-12861631636931259
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

POM121 ATN1 TRIP6 YLPM1 TNRC6B QSER1 TRIM24 AHDC1 CNOT2 NXF1 PRRC2B

5.96e-10457631132344865
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIPK3 TNRC18 MAPT KIAA0232 KIAA1217 FBXO42 CAMSAP3 RBM5 NAV1 TNRC6B QSER1 RAPGEF2 CDK14 AHDC1 THRAP3

4.88e-081489631528611215
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RAPGEF6 TRIP6 BAZ2A YLPM1 DACH1 TNRC6B CC2D1A QSER1 THRAP3 PRRC2B

5.35e-08549631038280479
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP1A TRIP6 MAPT ANXA1 YLPM1 TNRC6B POLR1B CC2D1A THRAP3 NXF1 PRRC2B

6.80e-08724631136232890
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TNRC18 MAGEL2 RAPGEF6 POM121 ATN1 MAP1A TRIP6 WEE1 YLPM1

8.15e-0843063935044719
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KALRN KIAA1217 NCAN YLPM1 CAMSAP3 NAV1 TNRC6B QSER1 RAPGEF2 THRAP3 PRRC2B ZIC2

1.38e-07963631228671696
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TNRC18 ATN1 YLPM1 QSER1 TRIM24 AHDC1 PRRC2B

5.71e-0726863733640491
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

GPALPP1 TNRC18 ANXA1 DACH1 RBM5 CC2D1A QSER1 TRIM24 AHDC1 THRAP3 NXF1 PRRC2B

5.86e-071103631234189442
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNRC18 MAP1A KALRN MAPT ANXA1 KIAA1217 CAMSAP3 NAV1 TNRC6B NACAD THRAP3 CNOT2

8.21e-071139631236417873
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CCP110 MAP1A TRIP6 WEE1 KIAA1217 FBXO42 NAV1 NXF1 PRRC2B

1.12e-0658863938580884
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MAP1A KALRN MAPT ANXA1 KIAA1217 NCAN ZNF185 CAMSAP3 NAV1 OGDHL RAPGEF2 THRAP3 PRRC2B

1.41e-061431631337142655
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

GPALPP1 KALRN ANXA1 CAMSAP3 TNRC6B PLG RAPGEF2 PRRC2B

2.29e-0647563831040226
Pubmed

A human MAP kinase interactome.

HIPK3 HDAC9 POM121 MAP1A KIAA0232 COBLL1 NAV1 RAPGEF2

2.71e-0648663820936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GPALPP1 HDAC9 CCP110 TNRC18 POM121 COBLL1 FBXO42 POM121B

3.01e-0649363815368895
Pubmed

The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.

RAPGEF6 RAPGEF2

3.23e-06263224858808
Pubmed

Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.

RAPGEF6 RAPGEF2

3.23e-06263232600317
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

WEE1 RBM5 NAV1 RAPGEF2 THRAP3 ZIC2

4.08e-0623263625515538
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ATN1 MAP1A TRIP6 BAZ2A MAPT WEE1 TNRC6B RAPGEF2 TRIM24 PRRC2B ZIC2

4.72e-061116631131753913
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

RAPGEF6 TRIP6 CAMSAP3 RBM5 TNRC6B RAPGEF2 AHDC1

5.56e-0637863734315543
Pubmed

Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1.

ANXA1 PLG

9.68e-06363228320709
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121 POM121B

9.68e-06363230802453
Pubmed

Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.

RAPGEF6 RAPGEF2

9.68e-06363229747665
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121 POM121B

9.68e-06363235507432
Pubmed

Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1.

LIMK1 ANXA1

9.68e-06363220061392
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

POM121 ATN1 TRIP6 KALRN TNRC6B AHDC1 NXF1 PRRC2B

1.39e-0560863816713569
Pubmed

The DNA sequence of human chromosome 7.

HDAC9 LIMK1 TNRC18 POM121 CDK14 POM121B NACAD

1.51e-0544163712853948
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

MAP1A ANXA1 ZNF185 DACH1 TNRC6B TRIM24 AHDC1

1.57e-0544463734795231
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

GPALPP1 CCP110 RAPGEF6 TRIP6 WEE1 KIAA1217 CC2D1A RAPGEF2 THRAP3 CNOT2

1.64e-051038631026673895
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121 POM121B

1.93e-05463217900573
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

MAP1A TRIP6 NAV1 TNRC6B TRIM24

2.15e-0518463532908313
Pubmed

Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).

LIMK1 POM121 POM121B

3.56e-053563311013070
Pubmed

The protein interaction landscape of the human CMGC kinase group.

HIPK3 CCP110 LIMK1 KIAA0232 NAV1 CDK14 THRAP3 CNOT2

3.59e-0569563823602568
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CCP110 RAPGEF6 MAP1A FBXO42 TNRC6B

3.96e-0520963536779422
Pubmed

Interaction network of human early embryonic transcription factors.

TNRC18 ATN1 QSER1 TRIM24 AHDC1 PRRC2B

4.24e-0535163638297188
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GPALPP1 RAPGEF6 MAP1A BAZ2A KIAA1217 YLPM1 TNRC6B CC2D1A PRRC2B

4.51e-0593463933916271
Pubmed

Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.

LIMK1 POM121 POM121B

4.57e-053863311779826
Pubmed

Human transcription factor protein interaction networks.

ATN1 TRIP6 YLPM1 DACH1 TNRC6B CC2D1A QSER1 TRIM24 CNOT2 NXF1 PRRC2B

4.68e-051429631135140242
Pubmed

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development.

CCP110 KIF12

4.82e-05663222851319
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

ATN1 ANXA1 YLPM1 RAPGEF2 THRAP3

5.05e-0522063524550385
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

MAP1A ANXA1 KIAA1217 ZNF185 YLPM1 RBM5 AHDC1 PRRC2B

5.17e-0573263834732716
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CCP110 YLPM1 RBM5 NAV1 TNRC6B POLR1B QSER1 CNOT2

5.22e-0573363834672954
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

WEE1 QSER1 TRIM24 PRRC2B

6.01e-0511663430804394
Pubmed

Tau knockout exacerbates degeneration of parvalbumin-positive neurons in substantia nigra pars reticulata in Parkinson's disease-related α-synuclein A53T mice.

MAP1A MAPT

6.74e-05763233000527
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RAPGEF6 ATN1 BAZ2A MAPT WEE1 YLPM1 CAMSAP3 THRAP3

7.63e-0577463815302935
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

TNRC6B POLR1B QSER1 NXF1 PRRC2B

7.92e-0524263534011540
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

GPALPP1 POM121 TRIP6 MAPT TNRC6B CC2D1A CNOT2 NXF1 PRRC2B

8.03e-05100763934597346
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

RAPGEF6 TRIP6 YLPM1 TNRC6B THRAP3

8.72e-0524763532989298
Pubmed

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation.

THRAP3 NXF1

8.98e-05863220123736
Pubmed

Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels.

MAP1A MAPT

8.98e-05863211085878
Pubmed

Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.

MAP1A MAPT

8.98e-05863226609151
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RAPGEF6 CAMSAP3 NAV1 TNRC6B TRIM24 NXF1

1.11e-0441863634709266
Pubmed

Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.

KIAA1217 AHDC1

1.15e-04963220139417
Pubmed

Tau haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and reduction of transcription factor orthodenticle homeobox 2 expression.

MAP1A MAPT

1.15e-04963228424350
Pubmed

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

MAPT NAV1

1.15e-04963226671463
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

POM121 TRIP6 KIAA1217 TNRC6B PRRC2B

1.17e-0426363534702444
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MAP1A KALRN YLPM1 RBM5 TNRC6B ZC3H6 AHDC1 THRAP3 NXF1

1.38e-04108263938697112
Pubmed

The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control.

THRAP3 NXF1

1.44e-041063218596238
Pubmed

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.

RAPGEF6 RAPGEF2

1.44e-041063223885123
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TRIP6 KIAA0232 KIAA1217 ZNF185 CAMSAP3 TNRC6B CC2D1A PRRC2B

1.49e-0485363828718761
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

MAP1A KALRN NCAN CAMSAP3 RAPGEF2

1.59e-0428163528706196
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TNRC18 RAPGEF6 KALRN NAV1 OGDHL CC2D1A AHDC1 TIAM2 PRRC2B

1.62e-04110563935748872
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

BAZ2A ANXA1 YLPM1 DACH1 THRAP3

1.65e-0428363530585729
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

ATN1 ZNF185 TNRC6B PRRC2B

1.71e-0415263438360978
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAPGEF6 ATN1 CAMSAP3 QSER1 MAP3K6 NXF1 PRRC2B

1.72e-0465063738777146
Pubmed

MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.

HDAC9 MAPT

1.76e-041163231223056
Pubmed

Role of Pax6 in development of the cerebellar system.

MAPT ZIC2

1.76e-041163210409504
Pubmed

Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.

MAP1A NXF1

1.76e-041163216014633
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HDAC9 HOXD1 TLE2 DACH1 POLR1B TRIM24 CNOT2 ZIC2

1.80e-0487763820211142
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

TNRC18 TRIP6 YLPM1 CAMSAP3 TNRC6B THRAP3 PRRC2B

1.81e-0465563735819319
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

MAPT CAMSAP3

2.11e-041263232839317
Pubmed

Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex.

RAPGEF6 RAPGEF2

2.49e-041363227390776
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

CCP110 KALRN COBLL1 CAMSAP3 CC2D1A THRAP3

3.00e-0450363616964243
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

RAPGEF6 RAPGEF2

3.34e-041563222797597
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

POM121 POM121B

3.34e-041563214697343
Pubmed

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.

TNRC6B CNOT2

3.34e-041563221981923
Pubmed

Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote.

QSER1 TRIM24

3.81e-041663216880268
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

HIPK3 KIAA1217 TNRC6B POLR1B AHDC1 CNOT2

4.29e-0453863610512203
Pubmed

New gene functions in megakaryopoiesis and platelet formation.

KALRN BAZ2A KIAA0232

4.37e-048163322139419
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

RBM5 MUC16 TNRC6B CC2D1A RAPGEF2 THRAP3 PRRC2B

5.05e-0477763735844135
Pubmed

A genomic atlas of mouse hypothalamic development.

MAGEL2 TRIP6 NCAN ZIC2

5.32e-0420563420436479
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

TRIP6 ANXA1 KIAA1217 COBLL1 ZNF185 CC2D1A

5.55e-0456563625468996
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CCP110 POM121 WEE1 COBLL1 CAMSAP3 NAV1 QSER1 CNOT2 PRRC2B

5.98e-04132163927173435
Pubmed

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

TNRC6B PRRC2B

6.63e-042163233029523
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ANXA1 COBLL1 YLPM1 RBM5 TNRC6B CC2D1A THRAP3 NXF1 PRRC2B

7.79e-04137163936244648
Pubmed

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.

ATN1 TNRC6B

7.97e-042363220696395
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP1A MAPT THRAP3 PRRC2B

8.31e-0423163416452087
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BAZ2A KIAA0232 NAV1 TNRC6B PRRC2B

8.62e-0440763512693553
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 CCP110 COBLL1 THRAP3

8.72e-0423463436243803
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIAA1217 NAV1 OGDHL

8.80e-0410363310574462
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FBXO42 DACH1 FOXO4 QSER1 TRIM24 THRAP3 ZIC2

8.98e-0485763725609649
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

BAZ2A RAPGEF2 NACAD

9.05e-041046339205841
Pubmed

Intermediate phenotypes identify divergent pathways to Alzheimer's disease.

RGSL1 MAPT

9.43e-042563220574532
Pubmed

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.

TNRC6B CC2D1A CNOT2

9.83e-0410763330995489
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

POM121 WEE1 YLPM1 POLR1B NXF1

1.22e-0344063534244565
Pubmed

Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.

MAPT ZIC2

1.27e-032963229874580
Pubmed

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.

POM121 ATN1

1.27e-032963217577209
Pubmed

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.

HDAC9 BAZ2A

1.27e-032963224105743
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

HIPK3 LIMK1 WEE1 ANXA1 CDK14 MAP3K6 THRAP3

1.27e-0391063736736316
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CCP110 RAPGEF6 NAV1 TNRC6B RAPGEF2

1.29e-0344663524255178
InteractionNUP35 interactions

POM121 ATN1 TRIP6 YLPM1 TNRC6B QSER1 TRIM24 AHDC1 CNOT2 NXF1 PRRC2B

7.24e-084246311int:NUP35
InteractionCEP128 interactions

CCP110 TRIP6 MAPT ANXA1 CAMSAP3 NAV1 TNRC6B CC2D1A NXF1

3.42e-07297639int:CEP128
InteractionSMG7 interactions

TLE2 FBXO42 YLPM1 DACH1 RBM5 TNRC6B TRIM24 CNOT2 PRRC2B

6.23e-07319639int:SMG7
InteractionYWHAH interactions

CCP110 RAPGEF6 TRIP6 MAPT WEE1 KIAA0232 KIAA1217 COBLL1 CAMSAP3 NAV1 CC2D1A FOXO4 RAPGEF2 CDK14 MAP3K6

1.09e-0611026315int:YWHAH
InteractionSFN interactions

HDAC9 CCP110 RAPGEF6 MAP1A MAPT WEE1 KIAA0232 COBLL1 CAMSAP3 NAV1 FOXO4 MAP3K6

1.31e-066926312int:SFN
InteractionHELZ interactions

POM121 TLE2 FBXO42 TNRC6B TRIM24 CNOT2 NXF1 PRRC2B

1.33e-06257638int:HELZ
InteractionGSK3A interactions

CCP110 TNRC18 RAPGEF6 MAP1A MAPT FBXO42 TNRC6B ZC3H6 AHDC1 THRAP3

1.63e-064646310int:GSK3A
InteractionYWHAZ interactions

HDAC9 CCP110 LIMK1 RAPGEF6 MAPT WEE1 ANXA1 KIAA0232 COBLL1 SH2D3C CAMSAP3 NAV1 FOXO4 RAPGEF2 CDK14 NXF1

2.02e-0613196316int:YWHAZ
InteractionTRIM36 interactions

CCP110 MAP1A MAPT CAMSAP3 NAV1 CC2D1A

5.83e-06144636int:TRIM36
InteractionGARRE1 interactions

TRIP6 FBXO42 TNRC6B TRIM24 CNOT2 PRRC2B

1.36e-05167636int:GARRE1
InteractionCEP85 interactions

TLE2 FBXO42 TNRC6B CNOT2 NXF1 PRRC2B

1.46e-05169636int:CEP85
InteractionEGR2 interactions

TNRC18 ATN1 QSER1 TRIM24 AHDC1 PRRC2B

1.56e-05171636int:EGR2
InteractionCEP135 interactions

CCP110 TRIP6 CAMSAP3 NAV1 TNRC6B CC2D1A PRRC2B

2.19e-05272637int:CEP135
InteractionSHANK3 interactions

ATN1 MAP1A KALRN MAPT KIAA0232 NCAN RBM5 RAPGEF2 THRAP3

2.24e-05496639int:SHANK3
InteractionYWHAG interactions

CCP110 RAPGEF6 MAPT WEE1 KIAA0232 COBLL1 SH2D3C CAMSAP3 NAV1 FOXO4 RAPGEF2 CDK14 MAP3K6 THRAP3

2.42e-0512486314int:YWHAG
InteractionCEP192 interactions

FBXO42 SH2D3C TNRC6B CNOT2 NXF1 PRRC2B

2.99e-05192636int:CEP192
InteractionSAMD4B interactions

CCP110 NAV1 TNRC6B CNOT2 PRRC2B

3.97e-05122635int:SAMD4B
InteractionMAGEA9 interactions

CCP110 RAPGEF6 CAMSAP3 RAPGEF2 TRIM24 CNOT2

4.68e-05208636int:MAGEA9
InteractionPCM1 interactions

CCP110 MAGEL2 KIAA1217 FBXO42 CAMSAP3 RBM5 NAV1 CC2D1A

5.96e-05434638int:PCM1
InteractionMEX3B interactions

TRIP6 CAMSAP3 TNRC6B CC2D1A CNOT2 PRRC2B

6.72e-05222636int:MEX3B
InteractionSYNE3 interactions

CCP110 TRIP6 KIAA1217 CAMSAP3 NAV1 TNRC6B CC2D1A PRRC2B

6.98e-05444638int:SYNE3
InteractionMAPRE3 interactions

CCP110 MAP1A MAPT KIAA1217 CAMSAP3 NAV1

8.17e-05230636int:MAPRE3
InteractionFBXO38 interactions

WEE1 QSER1 TRIM24 NXF1 PRRC2B

9.04e-05145635int:FBXO38
InteractionEYA4 interactions

ATN1 TRIP6 ZNF185 TNRC6B QSER1 PRRC2B

1.11e-04243636int:EYA4
InteractionYAP1 interactions

TNRC18 RAPGEF6 ATN1 TRIP6 BAZ2A YLPM1 DACH1 TNRC6B CC2D1A RAPGEF2 THRAP3 NXF1

1.27e-0410956312int:YAP1
InteractionGPBP1L1 interactions

FBXO42 TNRC6B CNOT2 NXF1

1.52e-0486634int:GPBP1L1
InteractionNAGK interactions

YLPM1 DACH1 AHDC1 PRRC2B ZIC2

1.52e-04162635int:NAGK
InteractionDCTN1 interactions

MAP1A MAPT ANXA1 KIAA1217 CAMSAP3 NAV1 CC2D1A NXF1

1.52e-04497638int:DCTN1
InteractionPRRC2B interactions

ATN1 FBXO42 TNRC6B CNOT2 NXF1 PRRC2B

1.77e-04265636int:PRRC2B
InteractionVIM interactions

CCP110 ATN1 MAPT WEE1 KIAA1217 CAMSAP3 NAV1 TNRC6B CC2D1A NXF1

1.81e-048046310int:VIM
InteractionTNIK interactions

KALRN MAPT KIAA1217 THRAP3 TIAM2 PRRC2B ZIC2

1.82e-04381637int:TNIK
InteractionEPB41L3 interactions

TNRC18 MAGEL2 KALRN MAPT DACH1 NACAD

2.04e-04272636int:EPB41L3
InteractionCNOT6L interactions

KIAA0232 TNRC6B CNOT2 PRRC2B

2.06e-0493634int:CNOT6L
InteractionAR interactions

HIPK3 TNRC18 ATN1 KIAA1217 YLPM1 SH2D3C QSER1 TRIM24 AHDC1 THRAP3 PRRC2B

2.28e-049926311int:AR
InteractionPPID interactions

GPALPP1 MAPT SH2D3C ZIC2

2.32e-0496634int:PPID
InteractionTNRC6B interactions

MAPT TNRC6B TRIM24 CNOT2 NXF1 PRRC2B

2.48e-04282636int:TNRC6B
InteractionAGO1 interactions

MAPT TNRC6B TRIM24 CNOT2 NXF1

2.68e-04183635int:AGO1
InteractionYWHAB interactions

CCP110 RAPGEF6 MAPT WEE1 KIAA0232 COBLL1 CAMSAP3 NAV1 FOXO4 RAPGEF2 CDK14

2.75e-0410146311int:YWHAB
InteractionDHX8 interactions

GPALPP1 YLPM1 RBM5 POLR1B THRAP3 NXF1

2.99e-04292636int:DHX8
InteractionVASP interactions

CCP110 MAP1A COBLL1 TNRC6B FYB1 NXF1

3.10e-04294636int:VASP
InteractionRBM14 interactions

HDAC9 LIMK1 ATN1 MAPT YLPM1 RBM5 CDK14 THRAP3

3.14e-04553638int:RBM14
InteractionRNF214 interactions

TRIP6 TNRC6B CNOT2 PRRC2B

3.16e-04104634int:RNF214
InteractionKCTD13 interactions

MAP1A KALRN MAPT ANXA1 KIAA1217 NCAN ZNF185 CAMSAP3 NAV1 OGDHL RAPGEF2 THRAP3 PRRC2B

3.16e-0413946313int:KCTD13
InteractionHNF1B interactions

DACH1 QSER1 TRIM24 THRAP3 PRRC2B

3.19e-04190635int:HNF1B
InteractionUBAP2L interactions

MAGEL2 MAPT TNRC6B CNOT2 NXF1 PRRC2B

3.33e-04298636int:UBAP2L
InteractionXRRA1 interactions

KIAA0232 NXF1

3.41e-049632int:XRRA1
InteractionSOX2 interactions

TNRC18 MAP1A ANXA1 KIAA1217 ZNF185 YLPM1 DACH1 RBM5 QSER1 TRIM24 AHDC1 THRAP3 PRRC2B

3.84e-0414226313int:SOX2
InteractionSYNGAP1 interactions

MAP1A TRIP6 KALRN MAPT NCAN RAPGEF2

3.90e-04307636int:SYNGAP1
InteractionADAM22 interactions

KALRN MAPT NXF1

4.02e-0446633int:ADAM22
InteractionCECR2 interactions

TRIP6 WEE1 PRRC2B

4.02e-0446633int:CECR2
InteractionCEBPA interactions

GPALPP1 TNRC18 ANXA1 DACH1 RBM5 CC2D1A QSER1 TRIM24 AHDC1 THRAP3 NXF1 PRRC2B

4.15e-0412456312int:CEBPA
InteractionNDC80 interactions

CCP110 KIAA1217 FBXO42 CAMSAP3 NAV1 NXF1

4.25e-04312636int:NDC80
InteractionATP5F1EP2 interactions

MAPT WEE1

4.26e-0410632int:ATP5F1EP2
InteractionHDAC4 interactions

GPALPP1 HDAC9 KALRN CAMSAP3 NAV1 TNRC6B RAPGEF2 THRAP3 PRRC2B

4.82e-04744639int:HDAC4
InteractionMAP1A interactions

MAP1A MAPT FBXO42 NXF1

4.94e-04117634int:MAP1A
InteractionCAMKV interactions

GPALPP1 TNRC18 MAPT THRAP3

5.10e-04118634int:CAMKV
InteractionRAPGEF4 interactions

MAP1A KALRN RAPGEF2

5.14e-0450633int:RAPGEF4
InteractionNINL interactions

CCP110 ANXA1 KIAA1217 CAMSAP3 TNRC6B CC2D1A PRRC2B

5.52e-04458637int:NINL
InteractionZC3H7A interactions

FBXO42 TNRC6B CC2D1A CNOT2 PRRC2B

5.61e-04215635int:ZC3H7A
InteractionTFEB interactions

MAPT FBXO42 DACH1

5.77e-0452633int:TFEB
InteractionPXN interactions

CCP110 LIMK1 TRIP6 KIAA1217 TNRC6B NXF1

6.08e-04334636int:PXN
InteractionYWHAQ interactions

CCP110 RAPGEF6 MAPT WEE1 ANXA1 COBLL1 CAMSAP3 NAV1 PLG RAPGEF2 CDK14

6.29e-0411186311int:YWHAQ
InteractionCTNND2 interactions

ATN1 KALRN MAPT

6.45e-0454633int:CTNND2
InteractionBTRC interactions

WEE1 RBM5 TNRC6B RAPGEF2 MAP3K6 THRAP3 CNOT2 NXF1 PRRC2B

6.46e-04775639int:BTRC
Cytoband7q11.23

LIMK1 POM121 POM121B

3.31e-04976337q11.23
GeneFamilyLIM domain containing

LIMK1 TRIP6 ZNF185

2.37e-04593731218
GeneFamilyPDZ domain containing

LIMK1 RAPGEF6 RAPGEF2 TIAM2

2.56e-041523741220
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC18 TNRC6B

1.19e-0325372775
GeneFamilyForkhead boxes

FOXD2 FOXO4

3.49e-0343372508
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MAPT YLPM1 CAMSAP3

5.97e-03181373694
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN TIAM2

8.05e-0366372722
CoexpressionGSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP

RAPGEF6 BAZ2A RBM5 TNRC6B FOXO4 TRIM24

7.89e-06200626M6019
CoexpressionGSE21033_3H_VS_24H_POLYIC_STIM_DC_UP

CABYR BAZ2A TNRC6B TRIM24 AHDC1

4.64e-05166625M7722
CoexpressionGENTILE_UV_HIGH_DOSE_DN

POM121 WEE1 RBM5 RAPGEF2 AHDC1 CNOT2

6.25e-05289626M13630
CoexpressionGSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN

HDAC9 CCP110 WEE1 CDK14 TIAM2

1.02e-04196625M4431
CoexpressionGSE22886_TCELL_VS_BCELL_NAIVE_DN

HDAC9 CCP110 COBLL1 CDK14 TIAM2

1.07e-04198625M4426
CoexpressionGSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP

BAZ2A RBM5 THRAP3 TIAM2 PRRC2B

1.09e-04199625M7325
CoexpressionGSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP

RBM5 TNRC6B FYB1 CNOT2 NXF1

1.09e-04199625M4460
CoexpressionGSE36078_WT_VS_IL1R_KO_LUNG_DC_DN

ANXA1 COBLL1 CC2D1A TIAM2 DMAC1

1.12e-04200625M9290
CoexpressionGSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN

TLE2 DACH1 POLR1B QSER1 CNOT2

1.12e-04200625M3904
CoexpressionSTARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP

TNRC18 POM121 ATN1 POM121B PRRC2B

1.34e-04208625MM581
CoexpressionLAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE

KIAA1217 COBLL1 DACH1 TNRC6B CDK14

1.34e-04208625M39233
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

ATN1 MAPT CAMSAP3 NAV1 TNRC6B PRRC2B

3.94e-07200636c92e4fc0442404481fcac623d691dae6215b852d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

FOXD2 KALRN NCAN DACH1 NAV1 ZIC2

3.94e-07200636332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellInfluenza_Severe-B_memory|World / Disease group and Cell class

RGSL1 WEE1 COBLL1 MUC16 CDK14

3.38e-0616263521eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABYR MAP1A KALRN COBLL1 TIAM2

4.40e-06171635b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABYR MAP1A KALRN COBLL1 TIAM2

4.40e-061716359d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

KALRN KIAA1217 SH2D3C DACH1 NAV1

6.62e-06186635c6075fe84226b370c5139066793844ad33ae2db1
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

KALRN KIAA1217 SH2D3C DACH1 NAV1

6.97e-061886353953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

KALRN KIAA1217 SH2D3C DACH1 RAPGEF2

7.16e-06189635fe49852ba15f948b384d6b4c258927c70b741357
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN KIAA1217 COBLL1 SH2D3C DACH1

7.34e-061906350e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN KIAA1217 SH2D3C DACH1 NAV1

7.92e-06193635f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

HDAC9 WEE1 COBLL1 CDK14 TIAM2

7.92e-061936357ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1 MAP3K6

7.92e-06193635e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1 MAP3K6

8.12e-061946357b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1 MAP3K6

8.33e-0619563519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

KALRN KIAA1217 SH2D3C DACH1 RAPGEF2

8.33e-0619563550a193475db1bb1e05b8590225a553688c372c14
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1 MAP3K6

8.75e-06197635f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HDAC9 MAP1A NCAN AHDC1

4.26e-05137634ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HDAC9 MAP1A NCAN AHDC1

4.26e-0513763447859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMK1 RGSL1 MAP1A MAPT

4.39e-05138634c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

HDAC9 KALRN SH2D3C DACH1

6.07e-051506344f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

MAP1A MAPT FOXO4 FYB1

6.39e-051526342ff0980dfd8d430cca14649151d856edef115720
ToppCellControl-MAIT|World / Disease group and Cell class

HDAC9 RAPGEF6 TLE2 TIAM2

8.37e-051636340ca4b835936b4f82217cbe57210c1dd90986c1d0
ToppCellInfluenza_Severe-B_memory|Influenza_Severe / Disease group and Cell class

WEE1 COBLL1 MUC16 CDK14

8.78e-0516563451172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF12 OGDHL PLG FYB1

8.78e-0516563434fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellCOVID-19_Mild-PLT_0|COVID-19_Mild / Disease Group and Platelet Clusters

ATN1 PLG FYB1 DMAC1

8.78e-05165634083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

HDAC9 MAP1A COBLL1 DACH1

9.41e-0516863490f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 CABYR RAPGEF6 TIAM2

9.63e-051696343f738fc56bbc70dc77c9ba41025631f8264cd2b3
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.01e-04171634bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

RGSL1 WEE1 COBLL1 MUC16

1.03e-041726340ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGSL1 MAP1A KALRN FYB1

1.05e-04173634f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCellControl-Myeloid-pDC|World / Disease state, Lineage and Cell class

HDAC9 MAP1A COBLL1 DACH1

1.18e-0417863420ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KALRN ANXA1 OGDHL FYB1

1.20e-04179634906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

KALRN KIAA1217 SH2D3C DACH1

1.23e-04180634b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellsevere-CD8+_T_naive|severe / disease stage, cell group and cell class

DNHD1 RGSL1 TRIP6 TRIM24

1.23e-0418063494fe530367b170777f4051a4034cff06d80dbb83
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

DNHD1 RGSL1 TRIP6 TRIM24

1.25e-0418163469eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

KALRN KIAA1217 SH2D3C DACH1

1.25e-04181634c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-immature_B_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HDAC9 RBM5 TNRC6B PLG

1.28e-04182634ab78df9de3878a6d67106a40094c893601de8076
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.28e-041826348b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.28e-04182634a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 WEE1 COBLL1 CDK14

1.31e-04183634ffa831f67ed005f05d1b80ebc707e046fc08e22f
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

KALRN SH2D3C NAV1 MAP3K6

1.31e-041836343c4153479fc4ab2d073d92cee120480015555914
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WEE1 COBLL1 CDK14 TIAM2

1.36e-0418563491c9a3ea1afd97d35bd05648875d29b35fe09128
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

KIAA1217 SH2D3C DACH1 NAV1

1.36e-0418563407f9f38f0739d7c830641723a38385550ac1ac92
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

KALRN KIAA1217 COBLL1 SH2D3C

1.36e-04185634a28187c2fd23564314b35759479ff2ca21f61485
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CCP110 TNRC18 MAPT TLE2

1.36e-04185634daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

XKR7 HOXD1 TLE2 KIAA1217

1.39e-04186634e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 SH2D3C DACH1 TRIM24

1.42e-04187634ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

HDAC9 KALRN DACH1 MAP3K6

1.42e-04187634e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1217 COBLL1 SH2D3C DACH1

1.42e-0418763497b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

KIAA1217 SH2D3C DACH1 NAV1

1.42e-04187634fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

KALRN KIAA1217 COBLL1 SH2D3C

1.42e-0418763454d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.45e-04188634e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN KIAA1217 SH2D3C DACH1

1.48e-04189634b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

KALRN KIAA1217 COBLL1 SH2D3C

1.48e-04189634ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellCOVID-19_Severe-Lymphoid_B-B_memory|COVID-19_Severe / Disease group, lineage and cell class

WEE1 COBLL1 CDK14 TIAM2

1.51e-04190634b6510c419a15ed049c0a0a6a6697b643668741c3
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

KALRN KIAA1217 COBLL1 SH2D3C

1.51e-04190634b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.51e-041906340a351609a72fd638c84b2435782e312ee6a33aac
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

HDAC9 WEE1 COBLL1 CDK14

1.54e-04191634c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.54e-04191634f229abf69a1217194f74b0502486907e07dba989
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.57e-041926341e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DACH1 TNRC6B RAPGEF2 CDK14

1.57e-04192634e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 COBLL1 SH2D3C DACH1

1.60e-04193634a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIAA1217 SH2D3C DACH1 NAV1

1.60e-04193634ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 KALRN SH2D3C NAV1

1.60e-04193634287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 SH2D3C DACH1 NAV1

1.64e-0419463443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 SH2D3C DACH1 NAV1

1.64e-041946341d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 SH2D3C DACH1 NAV1

1.64e-0419463458f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 SH2D3C DACH1 NAV1

1.64e-04194634bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NCAN MUC16 OGDHL FOXO4

1.64e-041946342dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellAdult-Endothelial|Adult / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.64e-04194634963b3fbee0575af8379baa397ace65949eaf34f7
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1

1.67e-04195634fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.67e-04195634094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

KALRN KIAA1217 SH2D3C DACH1

1.70e-0419663449cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN KIAA1217 SH2D3C DACH1

1.70e-04196634686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellsevere_COVID-19-B_memory|severe_COVID-19 / disease group, cell group and cell class (v2)

WEE1 COBLL1 CDK14 TIAM2

1.70e-04196634c6e00cb59a88b9903cca233cefe05f80c5ea4153
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIAA1217 SH2D3C DACH1 NAV1

1.70e-04196634ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

KALRN KIAA1217 SH2D3C DACH1

1.70e-0419663496c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

KALRN KIAA1217 SH2D3C DACH1

1.70e-041966344ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

TRIP6 WEE1 ANXA1 DACH1

1.74e-0419763461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MAP1A KALRN MAPT SH2D3C

1.74e-04197634c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

KIAA1217 SH2D3C DACH1 NAV1

1.74e-041976347e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN KIAA1217 SH2D3C DACH1

1.74e-04197634ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1217 SH2D3C DACH1 NAV1

1.74e-0419763481718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANXA1 KIAA1217 ZNF185 MUC16

1.74e-041976345c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

KALRN KIAA1217 SH2D3C DACH1

1.74e-04197634ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

TRIP6 WEE1 ANXA1 DACH1

1.74e-041976349d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN KIAA1217 SH2D3C DACH1

1.77e-04198634a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1217 SH2D3C DACH1 NAV1

1.77e-041986341d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

KIAA1217 SH2D3C DACH1 NAV1

1.80e-04199634793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellBronchial-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN KIAA1217 SH2D3C DACH1

1.80e-0419963436a230b80096455df26c2e2c8c05fd6b231508c5
ToppCellParenchymal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN SH2D3C DACH1 NAV1

1.80e-04199634a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN SH2D3C DACH1 NAV1

1.80e-04199634d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 KALRN SH2D3C DACH1

1.80e-04199634e2d5c5cab102e67b0131b02392d81adaedc15965
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN SH2D3C DACH1 NAV1

1.80e-04199634dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-B-B_memory|COVID-19_Severe / Disease, condition lineage and cell class

WEE1 COBLL1 CDK14 TIAM2

1.80e-0419963424c05faa825c9d55279956469862440f9914a280
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial-oRG|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

TRIP6 ANXA1 NCAN DACH1

1.80e-04199634151bda6821b52cfb4491474892ecb45781522837
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

WEE1 DACH1 NAV1 TRIM24

1.80e-04199634358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN KIAA1217 SH2D3C DACH1

1.84e-04200634105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KALRN PRRC2B ZIC2

2.91e-049163325197fde8b9bdaf1e28add695d13aff3ff52d86e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related-Oligodendrocyte/OPC|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KALRN PRRC2B ZIC2

2.91e-0491633ed4a48e5e5f5d8aadbc7b1b8d84a5f6363a08b85
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

GPALPP1 KIAA0232 RBM5 RAPGEF2 TRIM24 CNOT2

8.41e-061826063887_DN
DrugApigenin [520-36-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A

HDAC9 KALRN FBXO42 CC2D1A CDK14 FYB1

1.21e-051946064401_UP
DrugST021200; Up 200; 10uM; PC3; HT_HG-U133A

BAZ2A FBXO42 YLPM1 POLR1B CC2D1A PRRC2B

1.25e-051956067559_UP
DrugOxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A

HIPK3 BAZ2A RBM5 FOXO4 CDK14 FYB1

1.25e-051956064969_UP
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

HIPK3 ATN1 RBM5 QSER1 RAPGEF2 AHDC1

1.28e-05196606990_UP
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

CABYR BAZ2A YLPM1 DACH1 POLR1B RAPGEF2

1.28e-051966061629_DN
Drugrotenone; Down 200; 1uM; PC3; HT_HG-U133A

HIPK3 ATN1 HOXD1 MAPT OGDHL CDK14

1.32e-051976065948_DN
Drugtroglitazone; Down 200; 10uM; MCF7; HT_HG-U133A

HIPK3 LIMK1 ATN1 BAZ2A TLE2 CC2D1A

1.32e-051976065592_DN
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

LIMK1 ATN1 HOXD1 TLE2 YLPM1 DACH1

1.36e-051986064762_DN
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A

BAZ2A FBXO42 YLPM1 CC2D1A AHDC1 PRRC2B

1.36e-051986067180_DN
Drug17-AAG; Up 200; 1uM; HL60; HT_HG-U133A

HIPK3 MAP1A ANXA1 FOXO4 QSER1

1.04e-041776052678_UP
Drug17-AAG; Down 200; 1uM; PC3; HT_HG-U133A

HDAC9 WEE1 TNRC6B CC2D1A CDK14

1.41e-041896051206_DN
Drug2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A

CABYR MAP1A MAPT COBLL1 NCAN

1.56e-041936055600_UP
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; PC3; HT_HG-U133A

HIPK3 LIMK1 HOXD1 WEE1 QSER1

1.56e-041936054443_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

ATN1 BAZ2A MAPT FYB1 PRRC2B

1.56e-041936054186_DN
DrugRacecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

LIMK1 BAZ2A TLE2 YLPM1 AHDC1

1.59e-041946055755_DN
DrugSC 19220; Up 200; 10uM; PC3; HT_HG-U133A

BAZ2A TLE2 COBLL1 RBM5 FYB1

1.59e-041946057065_UP
DrugCyproterone acetate [427-51-0]; Down 200; 9.6uM; PC3; HT_HG-U133A

MAP1A BAZ2A MAPT TNRC6B FYB1

1.59e-041946054470_DN
DrugBufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A

HIPK3 LIMK1 ATN1 MAPT FYB1

1.59e-041946057413_UP
Drug0393-0188; Up 200; 10uM; MCF7; HT_HG-U133A

HIPK3 LIMK1 MAPT TLE2 RBM5

1.63e-041956057531_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A

HIPK3 LIMK1 BAZ2A MAPT COBLL1

1.63e-041956053732_DN
DrugPronethalol hydrochloride [51-02-5]; Down 200; 15uM; PC3; HT_HG-U133A

CABYR LIMK1 CC2D1A QSER1 FYB1

1.63e-041956053984_DN
DrugPiperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A

HOXD1 BAZ2A MAPT RAPGEF2 MAP3K6

1.67e-041966053263_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A

CCP110 BAZ2A COBLL1 YLPM1 QSER1

1.67e-041966056637_DN
DrugEtidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; PC3; HT_HG-U133A

ATN1 BAZ2A MAPT TLE2 FOXO4

1.67e-041966054564_UP
DrugDNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A

ATN1 BAZ2A WEE1 COBLL1 DACH1

1.67e-041966057513_DN
DrugTremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A

HIPK3 FBXO42 CC2D1A QSER1 FYB1

1.67e-041966056273_UP
DrugAH6809; Up 200; 1uM; PC3; HT_HG-U133A

LIMK1 MAP1A KALRN BAZ2A FYB1

1.71e-041976057049_UP
DrugSulfathiazole [72-14-0]; Down 200; 15.6uM; PC3; HT_HG-U133A

CABYR ATN1 MAPT TNRC6B FYB1

1.71e-041976054183_DN
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

HIPK3 ATN1 BAZ2A TLE2 CC2D1A

1.71e-041976055703_UP
DrugMetronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A

LIMK1 KIAA0232 OGDHL RAPGEF2 AHDC1

1.71e-041976051503_UP
DrugMethiazole; Down 200; 15uM; PC3; HT_HG-U133A

LIMK1 BAZ2A CC2D1A MAP3K6 AHDC1

1.71e-041976054532_DN
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A

ATN1 MAPT TLE2 CDK14 FYB1

1.71e-041976055939_UP
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A

ATN1 MAP1A TLE2 COBLL1 CDK14

1.71e-041976055633_UP
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

BAZ2A MAPT RBM5 RAPGEF2 FYB1

1.71e-041976052860_UP
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

LIMK1 MAPT TLE2 RBM5 CDK14

1.71e-041976057533_UP
DrugBepridil hydrochloride [74764-40-2]; Down 200; 10uM; PC3; HT_HG-U133A

GPALPP1 LIMK1 ATN1 BAZ2A TLE2

1.71e-041976054613_DN
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

HIPK3 LIMK1 ATN1 MAPT MAP3K6

1.71e-041976055055_DN
DrugFoliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A

LIMK1 ATN1 MAP1A MAPT YLPM1

1.71e-041976054295_DN
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

LIMK1 TLE2 DACH1 QSER1 RAPGEF2

1.71e-041976054745_DN
DrugPirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; HL60; HG-U133A

ATN1 HOXD1 FBXO42 YLPM1 TNRC6B

1.71e-041976051388_UP
Drugprochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A

GPALPP1 CABYR FBXO42 YLPM1 PRRC2B

1.71e-041976051215_DN
DrugTomatidine [77-59-8]; Down 200; 9.6uM; MCF7; HT_HG-U133A

BAZ2A WEE1 COBLL1 CC2D1A AHDC1

1.75e-041986057166_DN
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A

HIPK3 HOXD1 BAZ2A DACH1 FYB1

1.75e-041986056023_DN
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A

MAPT ANXA1 COBLL1 FBXO42 POLR1B

1.75e-041986051633_DN
DrugOrnidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A

HIPK3 LIMK1 ATN1 MAP1A CC2D1A

1.75e-041986055064_DN
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

MAPT TLE2 FBXO42 RBM5 QSER1

1.75e-041986055786_DN
DrugEthambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HG-U133A

CCP110 YLPM1 CC2D1A RAPGEF2 PRRC2B

1.75e-041986051900_DN
DrugBetaxolol hydrochloride [63659-19-8]; Up 200; 11.6uM; PC3; HT_HG-U133A

FOXD2 HOXD1 COBLL1 CC2D1A FOXO4

1.75e-041986054608_UP
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A

LIMK1 ATN1 BAZ2A OGDHL PRRC2B

1.75e-041986053756_DN
DrugIsocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A

BAZ2A MAPT WEE1 COBLL1 MAP3K6

1.75e-041986053424_DN
DrugGabapentin [60142-96-3]; Down 200; 23.4uM; PC3; HT_HG-U133A

HDAC9 MAPT YLPM1 RAPGEF2 AHDC1

1.79e-041996055875_DN
DrugNorcyclobenzaprine [303-50-4]; Up 200; 15.4uM; HL60; HT_HG-U133A

FOXD2 NCAN ZNF185 YLPM1 MAP3K6

1.79e-041996052469_UP
Drughaloperidol; Up 200; 10uM; HL60; HT_HG-U133A

HIPK3 ATN1 HOXD1 BAZ2A QSER1

1.79e-041996052663_UP
DrugTriprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; HL60; HT_HG-U133A

LIMK1 COBLL1 CC2D1A FOXO4 FYB1

1.79e-041996052376_UP
Drugalpha-estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A

GPALPP1 BAZ2A COBLL1 FBXO42 YLPM1

1.79e-041996051210_DN
DrugSisomicin sulfate [53179-09-2]; Down 200; 2.8uM; PC3; HT_HG-U133A

CABYR LIMK1 MAPT COBLL1 RBM5

1.84e-042006054014_DN
DrugAmidopyrine [58-15-1]; Down 200; 17.2uM; HL60; HG-U133A

HDAC9 WEE1 YLPM1 RAPGEF2 PRRC2B

1.84e-042006051376_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HG-U133A

HOXD1 TRIP6 WEE1 KIAA0232 YLPM1

1.84e-042006051939_UP
DrugStrophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

BAZ2A TNRC6B POLR1B CC2D1A AHDC1

1.84e-042006057182_DN
DrugOrnidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A

HDAC9 LIMK1 BAZ2A FOXO4 CDK14

1.84e-042006052272_UP
Diseasecoronary atherosclerosis measurement

HDAC9 NAV1

4.33e-055622EFO_0007938
Diseaseabdominal aortic artery calcification

HDAC9 NAV1

9.06e-057622EFO_0004859
Diseasecholesteryl esters to total lipids in small LDL percentage

COBLL1 NCAN PLG

9.57e-0542623EFO_0022255
Diseaseaortic measurement

HDAC9 LIMK1 KALRN NAV1 TNRC6B

1.87e-04251625EFO_0020865
Diseasefish oil supplement exposure measurement, triglyceride measurement

MAP1A NCAN

1.93e-0410622EFO_0004530, EFO_0600007
Diseasedry eye syndrome (is_marker_for)

ANXA1 MUC16

1.93e-0410622DOID:10140 (is_marker_for)
Diseaseandrostenedione measurement, estrone measurement

CDK14 DMAC1

6.50e-0418622EFO_0007970, EFO_0007972
DiseaseOsteoarthritis of hip

HDAC9 MAPT

8.05e-0420622C0029410
Diseaseplatelet crit

HDAC9 MAP1A KALRN NCAN YLPM1 DACH1 POLR1B FYB1

8.25e-04952628EFO_0007985
Diseaseplatelet component distribution width

HDAC9 KALRN BAZ2A WEE1 KIAA0232 COBLL1 FYB1

1.01e-03755627EFO_0007984
Diseasetotal brain volume change measurement, age at assessment

COBLL1 DACH1

1.26e-0325622EFO_0008007, EFO_0021504
Diseasetriacylglycerol 52:6 measurement

NCAN DACH1

1.26e-0325622EFO_0010418
Diseasespontaneous preterm birth

HDAC9 KALRN KIAA1217

1.27e-03101623EFO_0006917
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

MAP1A COBLL1 NCAN PLG

1.28e-03224624EFO_0004574, EFO_0008317
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

COBLL1 NCAN PLG

1.62e-03110623EFO_0008317, EFO_0008596, EFO_0010351
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

COBLL1 NCAN PLG

1.62e-03110623EFO_0004574, EFO_0008317, EFO_0008596
Diseasealopecia

FOXD2 HDAC9 HOXD1 MAPT

1.67e-03241624MONDO_0004907
Diseaseneutrophil percentage of leukocytes

HDAC9 KALRN MAPT COBLL1 SH2D3C TNRC6B

1.76e-03610626EFO_0007990
Diseaseimmature platelet fraction

KALRN BAZ2A KIAA0232

1.80e-03114623EFO_0009187
Diseaseimmature platelet measurement

KALRN BAZ2A KIAA0232

2.03e-03119623EFO_0803541
DiseaseUnipolar Depression

HDAC9 KALRN CC2D1A PLG

2.17e-03259624C0041696
Diseasepulse pressure measurement

HDAC9 LIMK1 KIAA1217 COBLL1 NAV1 TNRC6B CDK14 AHDC1 DMAC1

2.40e-031392629EFO_0005763
Diseasebrain ischemia (implicated_via_orthology)

MAPT ANXA1

2.47e-0335622DOID:2316 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in medium LDL percentage

COBLL1 PLG

2.76e-0337622EFO_0022252
Diseaseandrogenetic alopecia

FOXD2 HDAC9 MAPT

2.79e-03133623EFO_0004191
Diseasevery low density lipoprotein particle size measurement

COBLL1 NCAN PLG

2.79e-03133623EFO_0008594
Diseaseoral microbiome measurement

HDAC9 KIAA1217

3.54e-0342622EFO_0801229
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement

COBLL1 DMAC1

3.71e-0343622EFO_0007788, EFO_0008343
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

COBLL1 NCAN PLG

4.13e-03153623EFO_0004611, EFO_0020946
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

COBLL1 NCAN PLG

4.13e-03153623EFO_0004611, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
PFLGSGATSYSKPPG

ERFL

201

A0A1W2PQ73
SYITAPPGTAAAPAK

DMAC1

11

Q96GE9
SGLKPSPSSGEGLYT

BAZ2A

21

Q9UIF9
VASSPAGYKTASPPG

ATN1

621

P54259
SGTSVKSSSGPFPPA

CABYR

461

O75952
PSSPTSPKFGKADSY

CDK14

121

O94921
YLSLSSTVLGPAPGP

DNHD1

4016

Q96M86
KASGTYAGPPTSALP

AHDC1

866

Q5TGY3
SSSCGPLPGKPVYST

DACH1

161

Q9UI36
GSFYLHSPEGPSKPS

CAMSAP3

481

Q9P1Y5
LKTFGAPRPYSSSGP

COBLL1

971

Q53SF7
SAIPSSGYPPSTTKI

QSER1

266

Q2KHR3
KSSKGGPGSAVSPYP

ANXA1

26

P04083
ASGSYPSPKAGATLV

FBXO42

166

Q6P3S6
PAAYSGSPKISSSPN

MUC16

1361

Q8WXI7
STPSGNGKYLPGAIT

MAP1A

1296

P78559
GPSAASETPKSLPYA

MAGEL2

806

Q9UJ55
GTYPKSVSPASGLPA

HOXD1

186

Q9GZZ0
TGSGKTYTLTGPPPQ

KIF12

106

Q96FN5
PSPPKRCLSYGGTSQ

MAP3K6

956

O95382
PASVSSYAGGVPPTL

FOXO4

286

P98177
GLPSESSSSSYPGPV

KIAA0232

11

Q92628
APTTLPPCKGSYFGT

NXF1

366

Q9UBU9
SRSSGPPATFPSSKG

OGDHL

31

Q9ULD0
SKGQTSYSTTSLPPP

FYB1

381

O15117
YSSVPAGSEKPPKGS

KALRN

2266

O60229
SPAYTGFPLSPTKLS

HIPK3

1196

Q9H422
PAASPTGVVPGTKYA

RBM5

441

P52756
FGSSAKSPLPSYPGA

POM121B

536

A6NF01
PFGSSAKSPLPSYPG

POM121

951

Q96HA1
AGPALPPNYKSSSSD

GPALPP1

31

Q8IXQ4
AIGKGPASTPTYSPA

CC2D1A

196

Q6P1N0
SLTGSYAKLPSPEPS

CCP110

356

O43303
DQSSPPLSGTSPSYK

HDAC9

186

Q9UKV0
PLSGTSPSYKYTLPG

HDAC9

191

Q9UKV0
SGGAATRSPLVKPPY

FOXD2

116

O60548
KPPSGIARPSTSGSF

NAV1

591

Q8NEY1
TSGSFGYKKPPPATG

NAV1

601

Q8NEY1
SPPKSTDKYPFSSGG

RGSL1

1001

A5PLK6
SPQGSPHKGYTLIPS

RAPGEF6

1241

Q8TEU7
YSKGLDASSPSAPLG

NCAN

786

O14594
SGGDFKPTSPSLPAS

KIAA1217

1786

Q5T5P2
PPSSGPTYQCLKGTG

PLG

266

P00747
PALPGSSYKDPTSSN

CNOT2

281

Q9NZN8
PQSSPRKGYTLAPSG

RAPGEF2

1121

Q9Y4G8
KSLLSLGSYPPAAGS

TNRC18

2496

O15417
LGSYPPAAGSSEPKA

TNRC18

2501

O15417
LSSPVGGSYNLPSLP

TRIM24

611

O15164
GPTPASYTTASTPAG

TRIP6

151

Q15654
SSSPVKSPAAPYFLG

WEE1

121

P30291
PVGKSPPSTGSTYGS

THRAP3

316

Q9Y2W1
PGSPTPGPFSYTKAS

nan

61

Q6ZUT4
SGSGALPPYAPKLSS

ZC3H6

1016

P61129
YSEPAGSPGPAVSTK

XKR7

116

Q5GH72
SKSTSPGKYPHPGLA

TIAM2

1541

Q8IVF5
TYRPSSASPSGKPSG

PRRC2B

2156

Q5JSZ5
PKSGDRSGYSSPGSP

MAPT

506

P10636
ALPEASPGPGYSSST

YLPM1

26

P49750
GKASPSPSLSSYSDP

SH2D3C

476

Q8N5H7
GSLIYGFPPSSFSSP

TRIM64C

426

A6NLI5
PSGPSLKHLTDPSYG

POLR1B

11

Q9H9Y6
SSSLPSIPGGKPAYS

TLE2

406

Q04725
TANAGPPRPSSSGYK

ZNF185

121

O15231
SPFSPSPSYKLSPSG

TNRC6B

1156

Q9UPQ9
SPSYKLSPSGSTLPN

TNRC6B

1161

Q9UPQ9
PAASSGYESSTPPGL

ZIC2

426

O95409
GYESSTPPGLVSPSA

ZIC2

431

O95409
SPLSSPAYTPSGEAG

LIMK1

271

P53667
SPPASPSGSYITADG

NACAD

211

O15069