Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

3.79e-0651463GO:0050649
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.21e-05201464GO:0061665
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT78 KRT81 KRT83 KRT85 KRT86

1.50e-05431465GO:0030280
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

2.09e-0581463GO:0101021
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

6.05e-05111463GO:0101020
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 DOCK4 RANBP2 RGPD8 CYTH2 OBSCN RAP1GAP2 ANKRD27 SBF1 RGPD3 EIF2B5 BCAR3 RGPD5

9.19e-0550714613GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 DOCK4 RANBP2 RGPD8 CYTH2 OBSCN RAP1GAP2 ANKRD27 SBF1 RGPD3 EIF2B5 BCAR3 RGPD5

9.19e-0550714613GO:0030695
GeneOntologyMolecularFunctioncalcium ion binding

PCDHB10 ADAMTS13 F2 ITIH4 EHD3 MMRN1 SCUBE1 CELSR1 SCUBE2 AOC3 SCUBE3 MACF1 PLCB2 CDH5 PCDH7 CDH17

1.21e-0474914616GO:0005509
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

1.31e-04141463GO:0008401
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.35e-04361464GO:0019789
GeneOntologyMolecularFunctiontestosterone 16-alpha-hydroxylase activity

CYP3A4 CYP3A5

3.16e-0441462GO:0008390
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

4.86e-04501464GO:0003755
GeneOntologyMolecularFunctionvitamin D 23-hydroxylase activity

CYP3A4 CYP3A5

5.23e-0451462GO:0062179
GeneOntologyMolecularFunction1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity

CYP3A4 CYP3A5

5.23e-0451462GO:0062181
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 DOCK4 RANBP2 RGPD8 MYO1C ANKRD27 ITPKA RASIP1 RGPD3

6.04e-043211469GO:0031267
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

6.08e-04531464GO:0016859
GeneOntologyMolecularFunctionvitamin D3 25-hydroxylase activity

CYP3A4 CYP3A5

7.81e-0461462GO:0030343
GeneOntologyMolecularFunctionvitamin D 24-hydroxylase activity

CYP3A4 CYP3A5

7.81e-0461462GO:0070576
GeneOntologyMolecularFunctionstructural molecule activity

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 OBSCN NUP98 LAMB2 OGN BFSP1 MMRN1 NEFM DES NEFL MACF1

8.26e-0489114616GO:0005198
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 DOCK4 RANBP2 RGPD8 RAP1GAP2 ANKRD27 RGPD3 RGPD5

1.05e-032791468GO:0005096
GeneOntologyMolecularFunctionvitamin D 25-hydroxylase activity

CYP3A4 CYP3A5

1.09e-0371462GO:0070643
GeneOntologyMolecularFunctionGTPase binding

RGPD4 DOCK4 RANBP2 RGPD8 MYO1C ANKRD27 ITPKA RASIP1 RGPD3

1.35e-033601469GO:0051020
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP3A4 CYP3A5

1.44e-0381462GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP3A4 CYP3A5

1.44e-0381462GO:0034875
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK4 CYTH2 OBSCN ANKRD27 SBF1 EIF2B5 BCAR3

1.58e-032311467GO:0005085
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP3A7 CYP3A4 CYP3A5

1.94e-03341463GO:0008395
GeneOntologyMolecularFunctionaromatase activity

CYP3A7 CYP3A4 CYP3A5

2.11e-03351463GO:0070330
GeneOntologyMolecularFunctionoxygen binding

CYP3A7 CYP3A4 CYP3A5

2.48e-03371463GO:0019825
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

KRT16 BFSP1 NEFM DES NEFL

2.69e-031301465GO:0005200
GeneOntologyMolecularFunctioninositol phosphate kinase activity

ITPKA PPIP5K1

2.80e-03111462GO:0180030
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL MACF1

7.75e-119914111GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL MACF1

8.66e-1110014111GO:0045103
GeneOntologyBiologicalProcessintermediate filament organization

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL

9.17e-117514110GO:0045109
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.98e-07201415GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

2.57e-0791414GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

4.26e-07101414GO:1903301
GeneOntologyBiologicalProcessregulation of cell morphogenesis

DHX36 SPAG9 F2 ANKRD27 PTK2 CRK ITPKA TAOK2 IL1RAPL1 MACF1 HCK PLXNB3

1.16e-0630214112GO:0022604
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.43e-06131414GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.99e-06141414GO:1903299
GeneOntologyBiologicalProcesslipid hydroxylation

CYP3A7 CYP3A4 CYP3A5

2.55e-0591413GO:0002933
GeneOntologyBiologicalProcesskeratinization

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86

2.94e-05871416GO:0031424
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RANBP2 RGPD8 RGPD3 OGFOD1

3.36e-05541415GO:0018208
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RANBP2 OGT RGPD8 EPM2AIP1 RGPD3 TP53

3.83e-051341417GO:0010906
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

DHX36 SPAG9 YJEFN3 F2 ANKRD27 RYK PTK2 CRK ITPKA TAOK2 NEFM IL1RAPL1 NEFL CELSR1 BTBD7 DDHD1 MACF1 CDH5 HCK PLXNB3

5.28e-05109014120GO:0022603
GeneOntologyBiologicalProcessregulation of neurogenesis

DHX36 HAPLN2 F2 ANKRD27 RYK PTK2 ITPKA IL1RAPL1 NEFL SIRT2 MACF1 PLXNB3 TP53

5.43e-0551514113GO:0050767
GeneOntologyBiologicalProcessoxidative demethylation

CYP3A7 CYP3A4 CYP3A5

6.58e-05121413GO:0070989
GeneOntologyBiologicalProcessregulation of neuron projection development

DHX36 CYTH2 RAP1GAP2 ANKRD27 RYK PTK2 CRK ITPKA NEFM IL1RAPL1 NEFL TENM3 MACF1 PLXNB3

8.02e-0561214114GO:0010975
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RANBP2 OGT RGPD8 RGPD3

1.26e-04711415GO:0006111
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD8 RGPD3

1.29e-04381414GO:0000413
GeneOntologyBiologicalProcessneurofilament bundle assembly

NEFM NEFL

1.39e-0431412GO:0033693
GeneOntologyBiologicalProcesscell morphogenesis

DHX36 UNC5B LAMB2 SPAG9 F2 ANKRD27 RYK PTK2 CRK ITPKA TAOK2 NEFM IL1RAPL1 NEFL HRH2 MACF1 CDH5 HCK PLXNB3 CDH17

1.82e-04119414120GO:0000902
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

LAMB2 ADAMTS13 TEC PTK2 HCK CDH17

2.11e-041241416GO:0007229
GeneOntologyBiologicalProcessintermediate filament polymerization or depolymerization

NEFM NEFL

2.76e-0441412GO:0045105
GeneOntologyBiologicalProcessglucose metabolic process

RGPD4 RANBP2 OGT RGPD8 PFKL EPM2AIP1 RGPD3 TP53

2.80e-042441418GO:0006006
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RANBP2 OGT RGPD8 EPM2AIP1 RGPD3

2.96e-041321416GO:0043255
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHB10 CELSR1 TENM3 CDH5 PCDH7 PLXNB3 CDH17

3.06e-041871417GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHB10 TAOK2 IL1RAPL1 CELSR1 TENM3 CDH5 PCDH7 PLXNB3 CDH17

3.09e-043131419GO:0098742
GeneOntologyBiologicalProcesspositive regulation of execution phase of apoptosis

YJEFN3 SIRT2 TP53

3.27e-04201413GO:1900119
GeneOntologyBiologicalProcesscell junction organization

DHX36 OGT DRP2 MYO1C PCDHB10 LAMB2 RYK PTK2 CRK ITPKA TAOK2 IL1RAPL1 NEFL TENM3 MACF1 CDH5 CDH17

3.60e-0497414117GO:0034330
GeneOntologyBiologicalProcessregulation of nervous system development

DHX36 HAPLN2 F2 ANKRD27 RYK PTK2 ITPKA IL1RAPL1 NEFL SIRT2 MACF1 PLXNB3 TP53

3.65e-0462514113GO:0051960
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RANBP2 RGPD8 NUP98 RGPD3 TP53 RGPD5

3.94e-041951417GO:0006606
GeneOntologyBiologicalProcessalkaloid catabolic process

CYP3A4 CYP3A5

4.58e-0451412GO:0009822
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RANBP2 RGPD8 NUP98 RGPD3 TP53 RGPD5

4.73e-042011417GO:0051170
GeneOntologyBiologicalProcessdemethylation

CYP3A7 CYP3A4 CYP3A5

5.70e-04241413GO:0070988
GeneOntologyBiologicalProcessregulation of dendrite development

DHX36 CYTH2 ANKRD27 CRK ITPKA IL1RAPL1

5.86e-041501416GO:0050773
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

3.80e-09101465GO:0044614
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.24e-07181465GO:0044615
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD8 RGPD3

1.56e-0781464GO:1990723
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

2.21e-07201465GO:0042405
GeneOntologyCellularComponentintermediate filament

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL MACF1

5.89e-0722714611GO:0005882
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 RGPD8 RGPD3

2.16e-06141464GO:0005642
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL MACF1

2.48e-0626314611GO:0045111
GeneOntologyCellularComponentinclusion body

RGPD4 RANBP2 RGPD8 NUP98 RAD50 NEFM RGPD3

3.23e-06901467GO:0016234
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD8 RGPD3

1.25e-05211464GO:0106068
GeneOntologyCellularComponentkeratin filament

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86

6.14e-05971466GO:0045095
GeneOntologyCellularComponentnuclear pore

RGPD4 RANBP2 RGPD8 NUP98 RGPD3 RGPD5

7.69e-051011466GO:0005643
GeneOntologyCellularComponentpresynaptic intermediate filament cytoskeleton

NEFM NEFL

1.45e-0431462GO:0099182
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT78 KRT16 MYO1C KRT81 KRT83 KRT85 KRT86 DNAH2 BFSP1 NEFM DES NEFL SIRT2 EML5 MACF1 HCK CSTPP1

1.84e-0489914617GO:0099513
GeneOntologyCellularComponentpostsynaptic intermediate filament cytoskeleton

NEFM NEFL

2.88e-0441462GO:0099160
GeneOntologyCellularComponentsupramolecular fiber

KRT78 KRT16 MYO1C KRT81 KRT83 KRT85 KRT86 OBSCN DNAH2 BFSP1 NEFM DES NEFL SIRT2 EML5 MACF1 CTPS1 HCK CSTPP1

5.70e-04117914619GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT78 KRT16 MYO1C KRT81 KRT83 KRT85 KRT86 OBSCN DNAH2 BFSP1 NEFM DES NEFL SIRT2 EML5 MACF1 CTPS1 HCK CSTPP1

6.19e-04118714619GO:0099081
GeneOntologyCellularComponentpostsynaptic cytoskeleton

ITPKA NEFM NEFL

7.71e-04261463GO:0099571
GeneOntologyCellularComponentneuromuscular junction

LAMB2 CRK NEFM DES NEFL

1.14e-031121465GO:0031594
GeneOntologyCellularComponentnuclear protein-containing complex

RGPD4 DCAF1 TEAD2 RANBP2 OGT GTF2A1L RGPD8 MYO1C RBBP5 SF3A1 NUP98 E2F6 RAD50 DHX15 SIRT2 SUV39H1 RGPD3 IK TP53 RGPD5

1.46e-03137714620GO:0140513
GeneOntologyCellularComponentpresynaptic active zone membrane

KCTD12 APBA1 RYK TENM3

2.18e-03781464GO:0048787
GeneOntologyCellularComponentperinuclear region of cytoplasm

RGPD4 RANBP2 RGPD8 GDPD3 APBA1 RAP1GAP2 SPAG9 PTK2 EHD3 RAD50 RASIP1 SIRT2 SBF1 RGPD3 RASD1

2.29e-0393414615GO:0048471
HumanPhenoPerifollicular hyperkeratosis

KRT81 KRT83 KRT86

2.93e-064473HP:0007468
HumanPhenoBrittle hair

AARS1 KRT81 KRT83 KRT85 KRT86 SCUBE3

8.22e-0654476HP:0002299
HumanPhenoAbnormal perifollicular morphology

KRT81 KRT83 KRT86

1.44e-056473HP:0031285
HumanPhenoNail dystrophy

AARS1 KRT16 KRT81 KRT83 KRT85 KRT86 RBCK1 TP53

7.36e-05156478HP:0008404
HumanPhenoReduced peroxisomal glutaryl-CoA oxidase activity

GCDH SUGCT

8.33e-052472HP:0034688
MousePhenoaneuploidy

RGPD4 RANBP2 RGPD8 DIDO1 SIRT2 RGPD3 TP53

1.19e-06611267MP:0004024
MousePhenodecreased tumor latency

RGPD4 RANBP2 RGPD8 RGPD3 TP53

6.53e-06301265MP:0010308
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD8 RGPD3

1.05e-05161264MP:0003701
MousePhenoabnormal chromosome number

RGPD4 RANBP2 RGPD8 DIDO1 SIRT2 RGPD3 TP53

1.22e-05861267MP:0004023
MousePhenoabnormal tumor latency

RGPD4 RANBP2 RGPD8 RGPD3 TP53

1.24e-05341265MP:0010307
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RANBP2 RGPD8 SIRT2 RGPD3 TP53

3.89e-05701266MP:0003331
MousePhenoincreased respiratory system tumor incidence

RGPD4 RANBP2 RGPD8 SIRT2 RGPD3 HCK TP53

5.05e-051071267MP:0010298
MousePhenoincreased lung tumor incidence

RGPD4 RANBP2 RGPD8 SIRT2 RGPD3 HCK TP53

5.05e-051071267MP:0008014
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RANBP2 RGPD8 RAD50 SIRT2 RGPD3 TP53

6.39e-051111267MP:0010297
MousePhenoincreased liver tumor incidence

RGPD4 RANBP2 RGPD8 RAD50 SIRT2 RGPD3 TP53

6.39e-051111267MP:0008019
MousePhenoincreased lung carcinoma incidence

RGPD4 RANBP2 RGPD8 RGPD3 HCK TP53

7.19e-05781266MP:0008714
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD8 RGPD3

8.07e-05261264MP:0012058
MousePhenoabnormal chromosome morphology

RGPD4 RANBP2 RGPD8 DIDO1 SIRT2 RGPD3 TP53

1.42e-041261267MP:0003702
MousePhenofailure of blastocyst formation

RGPD4 RANBP2 RGPD8 RGPD3

1.64e-04311264MP:0012129
DomainFilament

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL

1.46e-107114210SM01391
DomainIF

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL

1.68e-107214210PS00226
DomainFilament

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL

1.94e-107314210PF00038
DomainIF

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 BFSP1 NEFM DES NEFL

2.92e-107614210IPR001664
DomainIntermediate_filament_CS

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 NEFM DES NEFL

1.10e-09631429IPR018039
DomainRan_BP1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.80e-08121425PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.80e-08121425PS50196
DomainRanBD

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

2.90e-08131425SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

2.90e-08131425IPR000156
DomainTPR_REGION

RGPD4 RANBP2 OGT RGPD8 DNAH2 TTC27 RGPD3 STIP1 LONRF3 DNAJC3 RGPD5

5.38e-0816514211PS50293
DomainTPR

RGPD4 RANBP2 OGT RGPD8 DNAH2 TTC27 RGPD3 STIP1 LONRF3 DNAJC3 RGPD5

5.38e-0816514211PS50005
DomainTPR-contain_dom

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 LONRF3 DNAJC3 RGPD5

2.22e-0715014210IPR013026
DomainTPR

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 LONRF3 DNAJC3

6.22e-071291429SM00028
DomainTPR_repeat

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 LONRF3 DNAJC3

8.06e-071331429IPR019734
DomainKeratin_2_head

KRT78 KRT81 KRT83 KRT85 KRT86

8.96e-07241425IPR032444
DomainKeratin_2_head

KRT78 KRT81 KRT83 KRT85 KRT86

8.96e-07241425PF16208
DomainGrip

RGPD4 RGPD8 RGPD3 RGPD5

1.01e-06111424SM00755
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

1.01e-06111424PF01465
DomainKeratin_II

KRT78 KRT81 KRT83 KRT85 KRT86

1.37e-06261425IPR003054
DomainGRIP_dom

RGPD4 RGPD8 RGPD3 RGPD5

1.51e-06121424IPR000237
DomainGRIP

RGPD4 RGPD8 RGPD3 RGPD5

1.51e-06121424PS50913
DomainCyt_P450_E_grp-II

CYP3A7 CYP3A4 CYP3A5

4.26e-0651423IPR002402
DomainCyt_P450_E_CYP3A

CYP3A7 CYP3A4 CYP3A5

8.46e-0661423IPR008072
DomainTPR-like_helical_dom

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 LONRF3 DNAJC3 RGPD5

1.19e-0523314210IPR011990
DomainRab_bind

RGPD4 RGPD8 RGPD3

1.47e-0571423PF16704
DomainFilament_head

NEFM DES NEFL

1.47e-0571423PF04732
DomainGCC2_Rab_bind

RGPD4 RGPD8 RGPD3

1.47e-0571423IPR032023
DomainIntermed_filament_DNA-bd

NEFM DES NEFL

1.47e-0571423IPR006821
DomainPH_dom-like

RGPD4 RANBP2 RGPD8 CYTH2 OBSCN APBA1 TEC NIBAN3 PTK2 SBF1 RGPD3 PLCB2 RGPD5

2.28e-0542614213IPR011993
Domain-

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 LONRF3 DNAJC3

2.97e-0520714291.25.40.10
Domain-

RGPD4 RGPD8 RGPD3

4.97e-051014231.10.220.60
DomainTPR_1

RANBP2 OGT RGPD8 STIP1 DNAJC3 RGPD5

6.40e-05901426IPR001440
DomainTPR_1

RANBP2 OGT RGPD8 STIP1 DNAJC3 RGPD5

6.40e-05901426PF00515
DomainEphrin_rec_like

SCUBE1 SCUBE2 SCUBE3

6.79e-05111423PF07699
DomainEGF_dom

SCUBE1 SCUBE2 SCUBE3

9.00e-05121423IPR024731
DomainEGF_3

SCUBE1 SCUBE2 SCUBE3

9.00e-05121423PF12947
DomainCA

PCDHB10 FREM2 CELSR1 CDH5 PCDH7 CDH17

2.48e-041151426SM00112
DomainCadherin

PCDHB10 FREM2 CELSR1 CDH5 PCDH7 CDH17

2.85e-041181426IPR002126
DomainWD40_repeat_dom

DCAF1 RBBP5 WDR81 SPAG9 NEDD1 TBL3 EML5 TENM3 WDR87

4.54e-042971429IPR017986
DomainCUB

ADAMTS13 SCUBE1 SCUBE2 SCUBE3

7.02e-04531424PS01180
Domain-

RGPD4 RANBP2 RGPD8 CYTH2 OBSCN APBA1 TEC NIBAN3 SBF1 RGPD3

8.26e-04391142102.30.29.30
Domain-

TDRD15 TDRD6

8.44e-04614222.40.50.90
DomainStaphylococal_nuclease_OB-fold

TDRD15 TDRD6

8.44e-0461422IPR016071
DomainPROTEIN_KINASE_TYR

OBSCN TEC RYK PTK2 HCK

8.71e-04971425PS00109
DomainTyr_kinase_AS

OBSCN TEC RYK PTK2 HCK

8.71e-04971425IPR008266
DomainEphrin_rec_like

SCUBE1 SCUBE2 SCUBE3

8.75e-04251423SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 SCUBE2 SCUBE3

8.75e-04251423IPR011641
DomainCUB_dom

ADAMTS13 SCUBE1 SCUBE2 SCUBE3

9.26e-04571424IPR000859
DomaincEGF

SCUBE1 SCUBE2 SCUBE3

9.84e-04261423PF12662
DomaincEGF

SCUBE1 SCUBE2 SCUBE3

9.84e-04261423IPR026823
Domain-

DCAF1 RBBP5 WDR81 SPAG9 NEDD1 TBL3 EML5 WDR87 PLXNB3

1.03e-0333314292.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 RBBP5 WDR81 SPAG9 NEDD1 TBL3 EML5 WDR87 PLXNB3

1.07e-033351429IPR015943
DomainTPR_11

OGT STIP1

1.18e-0371422PF13414
DomainGrowth_fac_rcpt_

KRT83 LAMB2 SCUBE1 CELSR1 SCUBE2 SCUBE3

1.24e-031561426IPR009030
DomainEGF-type_Asp/Asn_hydroxyl_site

MMRN1 SCUBE1 CELSR1 SCUBE2 SCUBE3

1.30e-031061425IPR000152
DomainCadherin_CS

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.47e-031091425IPR020894
DomainDUF1669

FAM83C FAM83F

1.56e-0381422PF07894
DomainDUF1669

FAM83C FAM83F

1.56e-0381422IPR012461
DomainCADHERIN_1

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.72e-031131425PS00232
DomainCadherin

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.72e-031131425PF00028
DomainCADHERIN_2

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.79e-031141425PS50268
Domain-

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.79e-0311414252.60.40.60
DomainCadherin-like

PCDHB10 CELSR1 CDH5 PCDH7 CDH17

1.93e-031161425IPR015919
DomainEGF

LAMB2 MMRN1 SCUBE1 CELSR1 SCUBE2 TENM3 SCUBE3

2.16e-032351427SM00181
DomainEGF_CA

MMRN1 SCUBE1 CELSR1 SCUBE2 SCUBE3

2.41e-031221425SM00179
DomainEGF-like_Ca-bd_dom

MMRN1 SCUBE1 CELSR1 SCUBE2 SCUBE3

2.58e-031241425IPR001881
DomainEGF-like_dom

LAMB2 MMRN1 SCUBE1 CELSR1 SCUBE2 TENM3 SCUBE3

2.98e-032491427IPR000742
DomainEGF_1

LAMB2 MMRN1 SCUBE1 CELSR1 SCUBE2 TENM3 SCUBE3

3.40e-032551427PS00022
DomainEGF-like_CS

LAMB2 MMRN1 SCUBE1 CELSR1 SCUBE2 TENM3 SCUBE3

3.86e-032611427IPR013032
DomainEGF_2

LAMB2 MMRN1 SCUBE1 CELSR1 SCUBE2 TENM3 SCUBE3

4.19e-032651427PS01186
DomainTyr_kinase_cat_dom

TEC RYK PTK2 HCK

4.56e-03881424IPR020635
DomainTyrKc

TEC RYK PTK2 HCK

4.56e-03881424SM00219
DomainTUDOR

TDRD15 TDRD6

4.92e-03141422PF00567
DomainWD_REPEATS_1

DCAF1 RBBP5 WDR81 NEDD1 TBL3 EML5 WDR87

5.43e-032781427PS00678
DomainWD_REPEATS_2

DCAF1 RBBP5 WDR81 NEDD1 TBL3 EML5 WDR87

5.53e-032791427PS50082
DomainWD_REPEATS_REGION

DCAF1 RBBP5 WDR81 NEDD1 TBL3 EML5 WDR87

5.53e-032791427PS50294
DomainCUB

SCUBE1 SCUBE2 SCUBE3

6.14e-03491423PF00431
DomainSH3

DOCK4 OBSCN TEC CRK MACF1 HCK

6.21e-032161426PS50002
DomainMethyltransf_11

NDUFAF5 METTL13

6.42e-03161422IPR013216
DomainMethyltransf_11

NDUFAF5 METTL13

6.42e-03161422PF08241
DomainCUB

SCUBE1 SCUBE2 SCUBE3

6.50e-03501423SM00042
DomainTPR_2

TTC27 STIP1 LONRF3

6.50e-03501423PF07719
DomainTPR_2

TTC27 STIP1 LONRF3

6.50e-03501423IPR013105
DomainSH3_domain

DOCK4 OBSCN TEC CRK MACF1 HCK

6.78e-032201426IPR001452
DomainASX_HYDROXYL

SCUBE1 CELSR1 SCUBE2 SCUBE3

7.15e-031001424PS00010
DomainDUF1605

DHX36 DHX15

7.24e-03171422IPR011709
DomainOB_NTP_bind

DHX36 DHX15

7.24e-03171422PF07717
Domain-

SCUBE1 SCUBE2 SCUBE3

7.24e-035214232.60.120.290
DomainSH2

TEC CRK BCAR3 HCK

7.40e-031011424PF00017
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD8 RGPD3

1.14e-05181144MM1549
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.66e-05401145MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.88e-05411145MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

2.12e-05421145MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

2.39e-05431145MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

3.70e-05471145MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

4.55e-05491145MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

5.02e-05501145MM14610
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RANBP2 RGPD8 NUP98 PFKL RGPD3

5.21e-05821146MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

5.53e-05511145MM15151
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86

7.26e-05871146MM15351
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

7.98e-05551145MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.03e-04581145MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.03e-04581145MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.78e-04651145MM15147
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 RANBP2 RGPD8 NUP98 NEDD1 CEP164 RGPD3 CEP131

2.33e-042021148MM15362
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

3.07e-04731145MM14948
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

5.88e-04841145MM14929
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86

6.22e-041291146M27649
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

6.55e-04861145MM15413
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 KCTD12 RANBP2 OGT RGPD8 NPEPPS CYTH2 MCC WDR81 DIDO1 PTK2 ITIH4 EPM2AIP1 EHD3 RAD50 TAOK2 NEFM NEFL SBF1 RGPD3 MACF1 CEP131 STIP1

3.02e-119631502328671696
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DOCK4 KCTD12 DHX36 RANBP2 KRT78 OGT MYO1C NPEPPS KRT85 SF3A1 NUP98 BAK1 MCC TTC27 SPAG9 PTK2 RAD50 METTL13 SIRT2 MTHFD1 EIF2B5 STIP1 LNPK BCAR3 CTPS1 DEDD

5.10e-1112841502617353931
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 RANBP2 OGT RGPD8 TTC27 E2F6 CRK RAD50 NEFM RGPD3 TMF1 CEP131 ZKSCAN4 PCCA CSTPP1

4.57e-104181501534709266
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX36 RANBP2 AARS1 MYO1C NPEPPS SF3A1 NUP98 DIDO1 SPAG9 TBL3 RAD50 DHX15 NEFM NEFL SBF1 MACF1 IK TP53

5.33e-106531501822586326
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT78 KRT81 KRT83 KRT85 KRT86

1.08e-0912150510692104
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

1.75e-0913150531427429
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KCTD12 DHX36 RANBP2 AARS1 ATP8B4 MYO1C RBBP5 NPEPPS SF3A1 NUP98 PFKL F2 TBL3 RAD50 DHX15 METTL13 MTHFD1 EIF2B5 STIP1 TDRD6 IK CTPS1 TP53 SOAT1 CKMT1A

2.38e-0914251502530948266
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-08715049037092
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150421205196
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150424403063
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150423536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150422821000
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD5

1.15e-087150415710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150438838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-08715047559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150438657106
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150425187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-08715048603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150426632511
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150423818861
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD8 RGPD3

1.15e-087150420682751
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

KCTD12 NPEPPS PFKL YJEFN3 OGN PTK2 EHD3 DHX15 NEFM NEFL SIRT2 MTHFD1 TDRD6 TSKS HCK CKMT1A

1.33e-086211501622794259
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD8 RGPD3

2.30e-088150421670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD8 RGPD3

2.30e-088150427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD8 RGPD3

2.30e-088150421310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD8 RGPD3

2.30e-088150422262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD8 RGPD3

2.30e-088150428745977
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150428100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150417887960
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-08915049733766
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150418394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150410601307
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD8 RGPD3

4.12e-089150428877029
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KCTD12 DHX36 KRT78 OGT KRT16 MYO1C NPEPPS CYTH2 HAPLN2 PFKL YJEFN3 ITPKA EHD3 DHX15 NEFM NEFL SIRT2 SBF1 MTHFD1 MACF1 STIP1 HCK CKMT1A

5.55e-0814311502337142655
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD8 RGPD3

6.84e-0810150416332688
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD8 RGPD3

6.84e-0810150427160050
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD8 RGPD3

6.84e-081015048857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD8 RGPD3

6.84e-0810150421859863
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT83 KRT86

7.86e-083150325557232
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT83 KRT86

7.86e-08315031372089
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT83 KRT86

7.86e-08315031712823
Pubmed

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150320615193
Pubmed

Sequences and differential expression of three novel human type-II hair keratins.

KRT83 KRT85 KRT86

7.86e-08315039084137
Pubmed

CYP3A Polymorphism and Chronic Mercury Intoxication.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150332146629
Pubmed

Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150317582393
Pubmed

The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150319801957
Pubmed

Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

SCUBE1 SCUBE2 SCUBE3

7.86e-083150312270931
Pubmed

Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150320621111
Pubmed

Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M.

OGT NEFM NEFL

7.86e-08315038344946
Pubmed

Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150320118548
Pubmed

The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients.

SCUBE1 SCUBE2 SCUBE3

7.86e-083150331991528
Pubmed

Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150323143891
Pubmed

Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150333866277
Pubmed

Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150332001245
Pubmed

CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.

CYP3A7 CYP3A4 CYP3A5

7.86e-083150334688813
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RANBP2 KRT78 KRT16 NPEPPS SF3A1 KRT86 NUP98 LAMB2 PFKL TBL3 RAD50 DHX15 NEFL MTHFD1 MACF1 CEP131 STIP1 IK TP53

1.01e-0710241501924711643
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD8 RGPD3

1.07e-0711150417069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD8 RGPD3

1.07e-0711150434110283
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD8 RGPD3

1.07e-0711150435771867
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

KCTD12 RANBP2 AARS1 SF3A1 NUP98 DIDO1 SPAG9 PFKL NEDD1 RAD50 SIRT2 MTHFD1 MACF1 STIP1 CTPS1 PCCA TP53 CSTPP1

1.29e-079341501833916271
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

DCAF1 KRT78 KRT16 MYO1C KRT81 KRT83 KRT85 KRT86 TEC CRK

2.65e-072661501019380743
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAF1 AARS1 OGT SF3A1 MCC SPAG9 NEDD1 EHD3 RAD50 DNAAF2 NEFM NEFL MB21D2 EML5 PDRG1 DDHD1 EIF2B5 CEP131 LNPK TP53 SOAT1

2.68e-0713211502127173435
Pubmed

Keratins of the human hair follicle.

KRT81 KRT83 KRT86

3.14e-074150315797458
Pubmed

Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.

CYP3A7 CYP3A4 CYP3A5

3.14e-074150334689350
Pubmed

CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.

CYP3A7 CYP3A4 CYP3A5

3.14e-074150318978522
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

3.14e-07415039480752
Pubmed

New consensus nomenclature for mammalian keratins.

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86

3.23e-0763150616831889
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

RGPD4 RGPD8 SF3A1 CRK DHX15 SIRT2 RGPD3 IK RGPD5

4.35e-07215150935973513
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 RGPD8 RGPD3

4.37e-0715150414697343
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

NPEPPS RYK FREM2 CELSR1 PCDH7 TP53

4.68e-0767150621875946
Pubmed

Comprehensive analysis of keratin gene clusters in humans and rodents.

KRT78 KRT81 KRT83 KRT86

5.81e-0716150415085952
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RANBP2 RGPD8 NUP98 RGPD3

6.25e-0738150512791264
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 DHX36 RANBP2 RGPD8 RBBP5 PFKL TBL3 RGPD3 IK CTPS1 TP53

6.79e-073701501122922362
Pubmed

Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes.

CYP3A7 CYP3A4 CYP3A5

7.81e-075150324168324
Pubmed

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

CYP3A7 CYP3A4 CYP3A5

7.81e-075150311266076
Pubmed

Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

CYP3A7 CYP3A4 CYP3A5

7.81e-075150311093772
Pubmed

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.

CYP3A7 CYP3A4 CYP3A5

7.81e-075150314559847
Pubmed

Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.

SCUBE1 SCUBE2 SCUBE3

7.81e-075150323383134
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DHX36 AARS1 OGT RBBP5 DIDO1 PFKL ANKRD27 PTK2 FREM2 SBF1 DDHD1 EIF2B5 AACS OGFOD1

9.60e-076501501438777146
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 DHX36 RANBP2 AARS1 MYO1C NPEPPS TTC27 PFKL ANKRD27 TBL3 PTK2 RAD50 DHX15 METTL13 SBF1 MTHFD1 EIF2B5 MACF1 IK CTPS1

1.62e-0613531502029467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 DOCK4 RAP1GAP2 ZHX2 EPM2AIP1 TENM3 BTBD7 OGFOD1 MACF1 PPIP5K1 PLXNB3

1.71e-064071501112693553
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

AARS1 OGT RBBP5 NPEPPS SF3A1 SPAG9 PFKL TBL3 DHX15 MTHFD1 STIP1 CTPS1

1.73e-064941501226831064
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RGPD4 DHX36 RANBP2 OGT RGPD8 MYO1C NPEPPS TTC27 GCDH PFKL TBL3 DHX15 METTL13 MTHFD1 RGPD3 IK CTPS1 CKMT1A RGPD5

2.19e-0612571501937317656
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD8 RGPD3

2.29e-0622150427717094
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

KCTD12 RANBP2 AARS1 OGT NPEPPS SF3A1 SPAG9 PFKL RAD50 DHX15 NEFM NEFL PDRG1 MTHFD1 MACF1 STIP1 CTPS1 TP53

2.52e-0611491501835446349
Pubmed

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.

CYP3A7 CYP3A4 CYP3A5

2.72e-067150311137287
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SCUBE1 SCUBE2 SCUBE3

2.72e-067150325639508
Pubmed

Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients.

CYP3A7 CYP3A4 CYP3A5

2.72e-067150319842932
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

KRT16 KRT81 KRT83 KRT85 SF3A1 KRT86 RAD50 IL1RAPL1 TDRD6

4.32e-06284150929459677
Pubmed

A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.

CYP3A7 CYP3A4 CYP3A5

4.33e-068150320147896
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RGPD4 RANBP2 RGPD8 PFKL RAD50 RGPD3

4.69e-0699150627746211
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RGPD4 RANBP2 RGPD8 SF3A1 RAD50 RGPD3 CTPS1

4.83e-06153150726365490
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TEAD2 RANBP2 OGT RBBP5 SF3A1 NUP98 SPAG9 E2F6 PFKL RAD50 NEFM DES METTL13 TMF1 TP53

4.94e-068571501525609649
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

RGPD4 RANBP2 AARS1 MYO1C NPEPPS TTC27 GCDH PFKL DES MTHFD1 CTPS1 TP53 CKMT1A

5.06e-066471501326618866
InteractionKRT19 interactions

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 CCDC77 CEP164 CRK BFSP1 NEFM DES SIRT2 CEP131

2.20e-0828214814int:KRT19
InteractionKRT37 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 MCC HAPLN2 NEFM DES

5.24e-081001489int:KRT37
InteractionKRT35 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HAPLN2 PRR35 HCK TP53

1.30e-071111489int:KRT35
InteractionKRT16 interactions

KRT78 KRT16 KRT81 KRT83 KRT85 KRT86 CRK EPM2AIP1 NEFM DES TP53

2.35e-0719714811int:KRT16
InteractionKRT33B interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HAPLN2 DES MB21D2

4.21e-07931488int:KRT33B
InteractionRGPD4 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

4.75e-07221485int:RGPD4
InteractionC2CD4B interactions

DCAF1 ADAMTS13 FREM2 CELSR1 MACF1 PCDH7

7.95e-07441486int:C2CD4B
InteractionADAMTS13 interactions

ADAMTS13 FREM2 CELSR1 MACF1 PCDH7

1.16e-06261485int:ADAMTS13
InteractionRGPD2 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

1.41e-06271485int:RGPD2
InteractionRGPD1 interactions

RGPD4 RANBP2 RGPD8 NUP98 RGPD3 RGPD5

1.53e-06491486int:RGPD1
InteractionKRT14 interactions

KRT78 DCPS KRT81 KRT85 KRT86 CRK NEFM DES NEFL TP53

1.59e-0619214810int:KRT14
InteractionOFD1 interactions

KRT81 KRT83 KRT86 CCDC77 NEDD1 CEP164 PTK2 RAD50 PDRG1 CEP131 STIP1 CTPS1 TP53

1.77e-0634714813int:OFD1
InteractionSIRT7 interactions

DCAF1 DHX36 RANBP2 AARS1 MYO1C NPEPPS SF3A1 NUP98 DIDO1 SPAG9 TBL3 RAD50 DHX15 NEFM NEFL SBF1 MACF1 IK TP53

2.31e-0674414819int:SIRT7
InteractionKRT27 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HAPLN2 BFSP1 NEFM NEFL TSKS

2.51e-0620214810int:KRT27
InteractionRANBP2 interactions

RGPD4 RANBP2 RGPD8 DCPS NUP98 RAD50 TAOK2 DHX15 RGPD3 STIP1 IK TP53 RGPD5

2.73e-0636114813int:RANBP2
InteractionSCUBE1 interactions

SCUBE1 SCUBE2 SCUBE3

3.84e-0651483int:SCUBE1
InteractionKRT39 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 NEFM

4.63e-06591486int:KRT39
InteractionKRT25 interactions

KRT78 KRT81 KRT83 KRT85 KRT86

5.43e-06351485int:KRT25
InteractionKRT15 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HAPLN2 CRK DES NEFL

6.83e-061781489int:KRT15
InteractionRICTOR interactions

RGPD4 DHX36 AARS1 KRT78 KRT16 RGPD8 MYO1C SF3A1 KRT86 TRIM52 CRK DHX15 SIRT2 MTHFD1 RGPD3 LNPK IK RGPD5

1.20e-0575914818int:RICTOR
InteractionBICD1 interactions

DOCK4 RANBP2 OGT NEDD1 CEP164 RAD50 NEFL TMF1 PCCA TP53

1.64e-0525014810int:BICD1
InteractionRGPD8 interactions

RGPD4 RANBP2 RGPD8 RGPD3 TSKS RGPD5

1.74e-05741486int:RGPD8
InteractionKRT36 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HCK

1.74e-05741486int:KRT36
InteractionKRT8 interactions

DOCK4 OGT KRT16 CCDC77 CRK NEFM DES NEFL SIRT2 CEP131 DEDD PCDH7 TP53

2.32e-0544114813int:KRT8
InteractionSASS6 interactions

RGPD8 KRT83 CCDC77 NEDD1 CEP164 BFSP1 CEP131 CSTPP1

2.33e-051591488int:SASS6
InteractionSUPT16H interactions

TEAD2 RANBP2 DCPS RBBP5 SF3A1 CEP164 DHX15 SBF1 GOLGA7 RASD1 STIP1 IK TP53

2.38e-0544214813int:SUPT16H
InteractionRGPD3 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

2.39e-05471485int:RGPD3
InteractionZWINT interactions

CCDC174 KRT83 NEDD1 BFSP1 NEFM RASIP1 LNPK TP53

2.44e-051601488int:ZWINT
InteractionKRT31 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 BAK1 HAPLN2 BFSP1 NEFM NEFL PRR35 SUV39H1 HCK

3.07e-0545314813int:KRT31
InteractionNUP62 interactions

RANBP2 OGT RGPD8 NUP98 BFSP1 NEFM RGPD3 STIP1 IK RGPD5

3.48e-0527314810int:NUP62
InteractionKRT38 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 MCC CEP164 NEFM

4.09e-051721488int:KRT38
InteractionCCDC92 interactions

RGPD8 CEP164 BFSP1 DES RGPD5

4.31e-05531485int:CCDC92
InteractionPHF21A interactions

RANBP2 OGT TTC27 E2F6 CRK RAD50 NEFM TMF1 CEP131 PCCA CSTPP1

4.75e-0534314811int:PHF21A
InteractionKRT2 interactions

OGT KRT16 DCPS CEP164 CRK DES SIRT2 CEP131 TP53

6.36e-052361489int:KRT2
InteractionKRT18 interactions

KRT16 KRT81 MCC CCDC77 DHX15 NEFM DES NEFL CEP131 DEDD DNAJC3 PCDH7

6.38e-0541914812int:KRT18
InteractionRGPD5 interactions

RGPD4 RANBP2 RGPD8 RGPD3 TSKS RGPD5

7.63e-05961486int:RGPD5
InteractionCYP3A5 interactions

CYP3A7 CYP3A4 CYP3A5

8.13e-05121483int:CYP3A5
InteractionKIF20A interactions

RGPD4 RANBP2 RGPD8 MYO1C NUP98 DIDO1 SPAG9 TBL3 ITIH4 DHX15 NEFM DES NEFL RGPD3 EIF2B5 MACF1 PPIP5K1 IK TRPV5 TP53

8.90e-05105214820int:KIF20A
InteractionBIRC3 interactions

KCTD12 DHX36 RANBP2 AARS1 ATP8B4 MYO1C RBBP5 NPEPPS SF3A1 NUP98 PFKL F2 TBL3 RBCK1 RAD50 DHX15 MTHFD1 STIP1 TDRD6 IK CTPS1 TP53 CKMT1A

1.11e-04133414823int:BIRC3
InteractionRCC1 interactions

TEAD2 RANBP2 OGT RGPD8 NUP98 RGPD3 TP53 RGPD5

1.22e-042011488int:RCC1
InteractionSYNC interactions

KRT16 MCC NEFM DES NEFL

1.34e-04671485int:SYNC
InteractionEED interactions

DCAF1 DHX36 RANBP2 AARS1 OGT DCPS MYO1C SF3A1 OBSCN NUP98 TTC27 DIDO1 E2F6 PFKL TBL3 RAD50 DHX15 SIRT2 MB21D2 MTHFD1 MACF1 IK CTPS1 SOAT1

1.37e-04144514824int:EED
InteractionCIT interactions

DHX36 RANBP2 AARS1 MYO1C RBBP5 NPEPPS SF3A1 NUP98 DIDO1 E2F6 PFKL TBL3 ITIH4 BFSP1 DHX15 NEFM DES NEFL SUV39H1 RGPD3 MACF1 IK TRPV5 TP53

1.45e-04145014824int:CIT
InteractionCOP1 interactions

DCAF1 OGT MYO1C CEP164 RAD50 MTHFD1 PPIP5K1 TSKS TP53 RGPD5

1.52e-0432614810int:COP1
InteractionTOP2B interactions

RANBP2 DCPS DNAH2 CEP164 TRIM52 RAD50 STIP1 IK TP53

1.58e-042661489int:TOP2B
InteractionHDAC1 interactions

DCAF1 RANBP2 OGT RBBP5 SF3A1 NUP98 TTC27 SPAG9 E2F6 ZHX2 CRK RAD50 NEFM SUV39H1 TMF1 CEP131 STIP1 PCCA TP53 CSTPP1

1.78e-04110814820int:HDAC1
InteractionNUMA1 interactions

RANBP2 KRT78 OGT RBBP5 DNAH2 NUP98 CRK RAD50 SUV39H1 RGPD3 MACF1 TP53

1.84e-0446914812int:NUMA1
InteractionPXN interactions

DOCK4 TEC NEDD1 PTK2 CRK MACF1 CEP131 BCAR3 HCK TP53

1.85e-0433414810int:PXN
InteractionPRRG4 interactions

TEC PTK2 AOC3 HCK

1.88e-04391484int:PRRG4
InteractionKDM1A interactions

RANBP2 OGT RBBP5 TTC27 E2F6 CRK RAD50 DHX15 NEFM NEFL SUV39H1 TMF1 CEP131 STIP1 IK PCCA TP53 CSTPP1

1.91e-0494114818int:KDM1A
InteractionRAN interactions

RGPD4 RANBP2 OGT RGPD8 RBBP5 NUP98 DHX15 SIRT2 RGPD3 STIP1 TP53 RGPD5

2.06e-0447514812int:RAN
InteractionTSKS interactions

RGPD8 SF3A1 TSKS RGPD5

2.08e-04401484int:TSKS
InteractionHTT interactions

KCTD12 OGT NPEPPS PFKL OGN PTK2 RBCK1 EHD3 DHX15 NEFM NEFL SIRT2 MTHFD1 AOC3 TDRD6 TSKS HCK TP53

2.12e-0494914818int:HTT
InteractionHDAC2 interactions

DCAF1 AARS1 KRT78 OGT KRT16 DCPS RBBP5 CCDC174 SPAG9 E2F6 PFKL ZHX2 DHX15 SUV39H1 STIP1 CTPS1 TP53

2.12e-0486514817int:HDAC2
InteractionXAGE1A interactions

DCAF1 FREM2 CELSR1 PCDH7

2.29e-04411484int:XAGE1A
InteractionLAG3 interactions

FREM2 CELSR1 PCDH7

2.45e-04171483int:LAG3
InteractionKRT34 interactions

KRT78 KRT81 KRT83 KRT85 KRT86 HAPLN2 PRR35 RASD1 HCK

2.50e-042831489int:KRT34
InteractionNPIPB6 interactions

RANBP2 RGPD8 RGPD5

2.92e-04181483int:NPIPB6
InteractionRCOR1 interactions

RANBP2 OGT LAMB2 SPAG9 E2F6 CRK RAD50 NEFM TMF1 CEP131 PCCA CSTPP1

2.95e-0449414812int:RCOR1
InteractionHPCA interactions

DNAAF2 PRR35 TP53 CKMT1A

3.02e-04441484int:HPCA
InteractionNAA40 interactions

KCTD12 RANBP2 AARS1 SF3A1 NUP98 DIDO1 SPAG9 PFKL NEDD1 RAD50 SIRT2 MTHFD1 MACF1 STIP1 CTPS1 PCCA TP53 CSTPP1

3.05e-0497814818int:NAA40
InteractionSCUBE2 interactions

SCUBE1 SCUBE2

3.18e-0441482int:SCUBE2
InteractionCEP128 interactions

DCPS CCDC77 NEDD1 CEP164 CRK RAD50 MB21D2 CEP131 TP53

3.56e-042971489int:CEP128
InteractionFLT1 interactions

DHX36 NPEPPS PFKL TEC PTK2 CRK HCK

3.62e-041791487int:FLT1
InteractionNPHP4 interactions

KRT16 MYO1C OBSCN TTC27 CEP164 TRIM52 NEFM STIP1

3.63e-042361488int:NPHP4
InteractionEEF1AKMT3 interactions

WDR81 ANKRD27 RBCK1 RAD50 METTL13 SBF1 AACS PPIP5K1 STIP1 RGPD5

3.67e-0436414810int:EEF1AKMT3
InteractionPCM1 interactions

KCTD12 KRT16 KRT81 KRT83 KRT86 CCDC77 NEDD1 CEP164 BFSP1 CEP131 CSTPP1

3.71e-0443414811int:PCM1
InteractionPLD1 interactions

DCAF1 MCC RYK EIF2B5 CDH5 TP53

4.00e-041301486int:PLD1
InteractionASNS interactions

AARS1 DCPS TTC27 MMRN1 AACS OGFOD1 STIP1

4.27e-041841487int:ASNS
Cytoband12q13

KRT81 KRT83 KRT85 KRT86

8.97e-0571150412q13
Cytoband17p13.3

MYO1C WDR81 RAP1GAP2 CRK

2.06e-0488150417p13.3
Cytoband7q21.1

CYP3A4 CYP3A5

2.93e-04815027q21.1
Cytoband15q15

PLCB2 CKMT1A

6.85e-0412150215q15
Cytoband2q31

CDCA7 LNPK

8.08e-041315022q31
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MYO1C DNAH2 WDR81 RAP1GAP2 CRK TP53

1.01e-033461506chr17p13
Cytoband2q12.3

RGPD4 RANBP2

1.40e-031715022q12.3
CytobandEnsembl 112 genes in cytogenetic band chr15q15

ITPKA PPIP5K1 PLCB2 CKMT1A

1.42e-031471504chr15q15
Cytoband2q13

RGPD8 RGPD3 RGPD5

1.47e-036815032q13
Cytoband8p21

NEFM NEFL

1.94e-032015028p21
Cytoband20p12.1

NDUFAF5 BFSP1

3.03e-0325150220p12.1
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 OGT RGPD8 TTC27 RGPD3 STIP1 DNAJC3 RGPD5

1.11e-08115979769
GeneFamilyKeratins, type II

KRT78 KRT81 KRT83 KRT85 KRT86

2.94e-0727975609
GeneFamilyCytochrome P450 family 3

CYP3A7 CYP3A4 CYP3A5

8.22e-0689731002
GeneFamilyIntermediate filaments Type IV

NEFM NEFL

4.21e-046972611
GeneFamilySH2 domain containing

TEC CRK BCAR3 HCK

2.14e-03101974741
GeneFamilyWD repeat domain containing

RBBP5 WDR81 NEDD1 TBL3 EML5 WDR87

2.88e-03262976362
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

WDR81 PTK2 NEFL TSKS PCDH7

2.92e-03181975694
GeneFamilyDEAH-box helicases

DHX36 DHX15

3.26e-0316972500
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RANBP2 RGPD8 DIDO1 RGPD3

4.49e-06431495MM3857
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200

DOCK4 DRP2 NEFM SCUBE1 TENM3 GUCY1B1 ETNK2 SOAT1

1.75e-051621478gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 EHD3 DES GUCY1B1 AOC3 SCUBE3 RASD1 BCAR3

1.90e-071811508429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 EHD3 DES GUCY1B1 AOC3 SCUBE3 RASD1 BCAR3

1.90e-071811508395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1L KRT16 UNC5B SOWAHD MCC EHD3 DES

1.96e-061721507073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES GUCY1B1 AOC3 SCUBE3 RASD1 BCAR3 TSKS

2.46e-061781507416f85e51f45ec7949451fd47611a84e33e87245
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAP1GAP2 PTK2 ITPKA NEFM NEFL SCUBE1 TENM3

3.29e-06186150756c139e679d640ea901ead657a8e8887e0fca098
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

CYP3A5 OBSCN MCC IL1RAPL1 RASIP1 BCAR3 CDH5

3.54e-061881507e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBA1 LAMB2 OGN DES GUCY1B1 AOC3 RASD1

3.54e-061881507d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCelldroplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT78 OGN ITIH4 DES GUCY1B1 AOC3 RASD1

3.79e-061901507e04f47705851563515b6a66a2634cf7a574f7bda
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.06e-06192150726d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 DES SCUBE2 GUCY1B1 AOC3 RASD1 BCAR3

4.06e-061921507eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCellP15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITIH4 EHD3 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.06e-061921507a476895b7b252c388d6346eacbc72f0115b1443e
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.20e-0619315079a2c1711dec9dd8c8313bcf25bb888ac8e86c3f3
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.20e-0619315077fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.20e-0619315077c7aa5e2124830d0fa1df11b6413ec6cf780aad0
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 SPAG9 RASIP1 SCUBE2 TMF1 MACF1 CDH5

4.35e-061941507e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

TEAD2 MB21D2 TENM3 AOC3 TDRD6 CDH5 PCDH7

4.35e-061941507eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.65e-0619615079a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.65e-06196150704dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.81e-0619715071a6b2ca94a4634c24cd95481576c955b20000a5f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.81e-06197150778d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.81e-06197150731bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.81e-061971507488e85991c5e668afb7672942726d9295b8fc7d8
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

OGN ITIH4 DES SUGCT AOC3 SCUBE3 CTPS1

5.14e-061991507056a28c36cd58dc695a5ae6f29b62135d6aad819
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCAF1 CYTH2 TRIM52 MMRN1 FREM2 ZKSCAN4

8.75e-061421506d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCAF1 CYTH2 TRIM52 MMRN1 FREM2 ZKSCAN4

8.75e-061421506a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KRT81 KRT86 RAP1GAP2 NIBAN3 RASD1 CKMT1A

2.20e-0516715068ddf9da71a7c4ed53588435db826563a24cee616
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD12 NEFL ETNK2 PLCB2 PCDH7 HCK

2.43e-05170150617bd7fd25a2657cb536ad47e294332920f759e95
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 SOWAHD TEC CCDC77 NEFM PCCA

2.43e-05170150665c7ed586e7615203a59999549892ed466a89502
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

ATP8B4 KRT81 KRT83 KRT86 MMRN1 TEC

2.68e-0517315064a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCelldroplet-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT81 KRT83 KRT85 KRT86 NIBAN3

2.72e-051041505a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD12 OBSCN APBA1 ITPKA FAM83F CDH5

2.95e-05176150674f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD12 OBSCN APBA1 ITPKA FAM83F CDH5

2.95e-05176150631b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES GUCY1B1 AOC3 SCUBE3 RASD1 TSKS

3.05e-051771506dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH2 NEDD1 F2 TENM3 CDCA7 SCUBE3

3.15e-0517815066178706db4a855d72abc156537604d575624df56
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GDPD3 ADAMTS13 TAOK2 DES CDCA7 SUV39H1

3.15e-051781506c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH2 NEDD1 F2 TENM3 CDCA7 SCUBE3

3.15e-051781506f02076ece0fa899e620971c887ad4da7f48684ed
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 DES GUCY1B1 AOC3 RASD1 BCAR3

3.25e-0517915068da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFAF5 ITIH4 DES GUCY1B1 AOC3 RASD1

3.25e-051791506d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFAF5 ITIH4 DES GUCY1B1 AOC3 RASD1

3.25e-0517915066be47c877250968a916c711ba0787eb7b4c5443d
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 DES GUCY1B1 AOC3 RASD1 BCAR3

3.25e-051791506f39c13c99a07d009cc677e363ffe089089c64916
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

KRT81 GDPD3 KRT83 KRT85 KRT86 PCDH7

3.25e-0517915061526a130565a97c291a25a7a988089bffc1515c1
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GTF2A1L RASIP1 DES AOC3 CDH5 PCDH7

3.35e-051801506455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B LAMB2 RYK EHD3 RASIP1 DES

3.45e-0518115064df7972f88117108698efd06b124b232f8588981
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B LAMB2 RYK EHD3 RASIP1 DES

3.45e-051811506cbb530566893281289026bfd93adf721decd4ca3
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

CYP3A5 MCC IL1RAPL1 RASIP1 BCAR3 CDH5

3.56e-0518215068b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TEAD2 CYP3A4 LAMB2 SCUBE2 TENM3 RASD1

3.67e-051831506ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 UNC5B MCC EHD3 RASIP1 CDH5

3.79e-051841506c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 ATP8B4 OGN IL1RAPL1 TENM3 ALDH1L2

3.79e-05184150667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellE17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PTK2 EHD3 DES GUCY1B1 AOC3 PCDH7

4.14e-0518715060dee138738b65531ff134a125b92234b5d0a653c
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UNC5B MCC EHD3 RASIP1 BCAR3 CDH5

4.27e-051881506789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCellP07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.27e-0518815066ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B4 KRT81 KRT83 KRT86 SCUBE1 STIP1

4.40e-0518915065c85656f555d91ecc9540faa67717694a4aef92f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OGN ITIH4 SCUBE2 TENM3 HRH2 PCDH7

4.40e-051891506e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellP03-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.40e-051891506b5439ef221106f6d54434f268485e9bb17b39102
ToppCelldroplet-Tongue-nan-3m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT81 UNC5B KRT83 KRT85 KRT86 PCDH7

4.53e-051901506251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP3A5 OBSCN MCC IL1RAPL1 RASIP1 CDH5

4.53e-0519015060a351609a72fd638c84b2435782e312ee6a33aac
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

DES GUCY1B1 ETNK2 AOC3 RASD1 BCAR3

4.53e-0519015065aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCTD12 OGN ITIH4 SCUBE2 HRH2 PCDH7

4.53e-051901506d60395739458d7f47a3350ade751fe3819500320
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES SCUBE2 GUCY1B1 AOC3 RASD1 BCAR3

4.66e-0519115065c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

HAPLN2 ITIH4 DES GUCY1B1 AOC3 HRH2

4.66e-0519115062da83c493e60ad0278848957645277d76737a188
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.80e-05192150687c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 DES GUCY1B1 AOC3 RASD1 BCAR3

4.94e-0519315061043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES FREM2 GUCY1B1 AOC3 CDH5

4.94e-0519315063a5090f81f35026f435f4a250d1e77601a53af15
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PTK2 DES GUCY1B1 AOC3 SCUBE3 HRH2

4.94e-0519315065260ac95a15cc43a19909badad0c7e3854da920d
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

4.94e-05193150688916d9a7d831eb52848599917c04238f8f9812b
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.94e-0519315068be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.94e-05193150619dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES FREM2 GUCY1B1 AOC3 CDH5

4.94e-05193150613731b7fc1e3bec0cebc44bad7e2ecea358bb76a
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHD3 RASIP1 SCUBE1 GUCY1B1 CDH5 PCDH7

4.94e-0519315062483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCelldroplet-Bladder-nan-3m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

4.94e-051931506351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES FREM2 GUCY1B1 AOC3 CDH5

4.94e-05193150688cd7d0d0da5c776b49fc131f746fe5ad9676fb7
ToppCellT_cells-CD56_bright_CD16-_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ATP8B4 KRT81 KRT86 APBA1 MMRN1 TEC

4.94e-051931506826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH4 DES GUCY1B1 AOC3 RASD1 BCAR3

4.94e-0519315060266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PTK2 DES GUCY1B1 AOC3 SCUBE3 HRH2

4.94e-0519315065ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OGN DES FREM2 AOC3 MACF1 PCDH7

4.94e-0519315060256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITIH4 DES GUCY1B1 AOC3 SCUBE3 PCDH7

5.08e-05194150683e45441c74b7f50b6725876b583229280179dc2
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASIP1 DES GUCY1B1 AOC3 RASD1 CDH5

5.08e-0519415069d7cbbcf995274019ca10be0562f114513ec197a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN DES GUCY1B1 ETNK2 AOC3 RASD1

5.08e-0519415063bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.08e-051941506aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OGN DES GUCY1B1 ETNK2 AOC3 RASD1

5.08e-051941506fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 OGN DES FREM2 AOC3 PCDH7

5.23e-0519515068a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TTC27 TEC ITPKA MMRN1 GUCY1B1 OGFOD1

5.23e-051951506fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.23e-05195150656e7cd980f8fc2dae842e6a7bd919d4b41cebbbb
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.23e-051951506a28a504c69bc4dda7de023e1b4ea4f62390b158e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 MYO1C UNC5B EHD3 RASIP1 CDH5

5.38e-05196150665d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

PTK2 ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.38e-051961506c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PTK2 ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.38e-0519615062f76f050083483f0880639e6c34ff349caac3503
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OGN ITIH4 DES GUCY1B1 AOC3 SCUBE3

5.38e-0519615064740ef6e428f1ccc81fc98c3b868afd38ce60535
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

KCTD12 DIDO1 DHX15 PDRG1 NBPF10 PLCB2

5.38e-05196150609d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

GDPD3 PTK2 CDCA7 SUGCT BCAR3 HCK

5.53e-051971506806dddcca85c82bd642008d930c8db16b613d88e
ToppCellmLN-(2)_B_cell-(24)_B_cell_cycling|mLN / shred on region, Cell_type, and subtype

GDPD3 PTK2 CDCA7 SUGCT BCAR3 HCK

5.53e-05197150670fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

DOCK4 KCTD12 TENM3 SUGCT MACF1 PCDH7

5.53e-051971506f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK4 OGN EML5 TENM3 HRH2 MACF1

5.69e-0519815060c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_3|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TEAD2 NEDD1 CDCA7 MTHFD1 CTPS1 TP53

5.85e-05199150679d87e2b0adeff2d33c3b699afe7211fddc4f285
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

UNC5B SOWAHD DNAH2 LAMB2 ADAMTS13 SCUBE3

6.02e-052001506aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

UNC5B SOWAHD DNAH2 LAMB2 ADAMTS13 SCUBE3

6.02e-052001506a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

RAP1GAP2 ZHX2 TRIM52 NBPF19 TDRD6

7.06e-0512715059071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP8B4 BAK1 RAP1GAP2 TEC MTHFD1

8.79e-05133150581189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYTH2 SIRT2 GOLGA7 CTPS1 PLXNB3

1.01e-04137150580f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAP1GAP2 MMRN1 METTL13 SUV39H1 OGFOD1

1.28e-0414415057c471e332f87d60f4dbed01f3e66bf39995218d0
ComputationalGenes in the cancer module 68.

KRT16 KRT85 KRT86 NEFL

6.23e-0526914MODULE_68
ComputationalKeratin.

KRT16 KRT85 KRT86 NEFL

6.23e-0526914MODULE_298
Drugamodiaquine

TEAD2 CYP3A4 CYP3A5 KRT81 KRT83 AOC3 TP53

6.62e-09401487CID000002165
Drugbisdesethylchloroquine

CYP3A4 CYP3A5 KRT81 KRT83

2.11e-0791484CID000122672
Drugterritrem C

CYP3A4 CYP3A5 AOC3

2.69e-0731483CID000160306
Drugterritrem B

CYP3A4 CYP3A5 AOC3

1.07e-0641483CID000114734
Drugpropionanilide

CYP3A7 GTF2A1L CYP3A4 CYP3A5

1.63e-06141484CID000012107
Drug2,4,5-trichlorophenol

CYP3A7 OGT DCPS CYP3A4 CYP3A5 TEC

1.69e-06561486CID000007271
Drugethylbenzene

AARS1 DCPS CYP3A5 KRT86 CRK AOC3

2.55e-06601486CID000007500
Drugethyl isocyanate

CYP3A4 CYP3A5 AOC3

2.67e-0651483CID000008022
Drugnoralfentanil

CYP3A7 GTF2A1L CYP3A4 CYP3A5

3.82e-06171484CID000162172
DrugAlfentanil

CYP3A7 CYP3A4 CYP3A5

5.31e-0661483ctd:D015760
DrugCID5475388

CYP3A7 CYP3A4 CYP3A5 AOC3

7.66e-06201484CID005475388
Drugartemether

TEAD2 CYP3A4 KRT81 KRT83

7.66e-06201484CID000068911
Drugcycloguanil

CYP3A4 CYP3A5 KRT81 KRT83

7.66e-06201484CID000009048
Drugcholine

TEAD2 KRT81 KRT83 SPAG9 F2 MTHFD1 ETNK2 EIF2B5 PLCB2 TP53 CKMT1A

8.23e-0632014811CID000000305
Drug4-formylbiphenyl

CYP3A4 CYP3A5 AOC3

9.24e-0671483CID000076689
Drug4-(4-chlorobenzyl)pyridine

CYP3A4 CYP3A5 AOC3

9.24e-0671483CID000078124
Drug2beta-hydroxytestosterone

CYP3A4 CYP3A5 AOC3

9.24e-0671483CID005207588
Drugpentachlorophenol

CYP3A7 DCPS CYP3A4 CYP3A5 TEC F2 PTK2

1.37e-051201487CID000000992
DrugAC1L2K1Q

CYP3A4 CYP3A5 KRT81 KRT83

1.38e-05231484CID000022258
Drugnafimidone

CYP3A4 CYP3A5 NEFM

1.47e-0581483CID000051199
Drugdiethylformamide

CYP3A4 CYP3A5 AOC3

1.47e-0581483CID000012051
DrugL-754394

CYP3A4 CYP3A5 AOC3

1.47e-0581483CID000153982
DrugAC1MI0E8

TEAD2 GCDH SUGCT

1.47e-0581483CID003036008
Drugdesethylchloroquine

CYP3A4 KRT81 KRT83

1.47e-0581483CID000095478
Drugteleocidin B

KRT16 KRT81 KRT83 KRT85 KRT86 SPAG9 TP53

1.61e-051231487CID000072425
DrugFlame Retardants

CYP3A4 RAD50 NEFM NEFL SBF1 TENM3 STIP1 LNPK TP53

1.77e-052261489ctd:D005411
DrugPD138142-15

CYP3A4 CYP3A5 SOAT1

2.20e-0591483CID003025787
Drugaflatoxin B1-8,9-epoxide

CYP3A5 RASD1 TP53

2.20e-0591483CID000104756
DrugS 840

CYP3A7 CYP3A4 CYP3A5

2.20e-0591483CID000096338
DrugFluorouracil

KCTD12 AARS1 KRT16 CYP3A4 UNC5B KRT86 BAK1 HAPLN2 F2 PTK2 CRK DHX15 DES SCUBE2 CDCA7 GUCY1B1 NBPF10 MACF1 BCAR3 CTPS1 CDH5 TP53 SOAT1

2.43e-05136414823ctd:D005472
DrugAC1L1CGL

RANBP2 DCPS CYP3A4 CYP3A5

2.68e-05271484CID000001889
Drugdimethyl sulfide

CYP3A4 TEC DES MTHFD1 TP53

2.90e-05551485CID000001068
Drug4-hydroxymidazolam

CYP3A7 CYP3A4 CYP3A5

3.12e-05101483CID000124449
Drugperillyl alcohol

CYP3A5 BAK1 AOC3 RASD1 TP53

3.17e-05561485CID000010819
Drugeconazole

AARS1 CYP3A4 CYP3A5 IK TRPV5

3.46e-05571485CID000003198
Drugbilobalide

CYP3A4 CYP3A5 AOC3 IK

4.12e-05301484CID000073581
Drugdihydroartemisinin

CYP3A4 CYP3A5 KRT81 KRT83

4.12e-05301484CID000107770
Drug4-hydroxymidazolam

CYP3A4 CYP3A5

4.20e-0521482ctd:C042940
DrugBenzo[b]phenanthro[2,3-d]thiophene

CYP3A5 TP53

4.20e-0521482CID006428586
Drugnorverapamil

CYP3A4 CYP3A5

4.20e-0521482ctd:C016904
Drug5,6-dihydro-2H-pyran-2-one

CYP3A4 CYP3A5

4.20e-0521482CID000520660
Drugnotopterol

CYP3A4 CYP3A5

4.20e-0521482CID005320227
Drugmelicopicine

KRT81 KRT83

4.20e-0521482CID000101253
DrugN-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide

CYP3A4 CYP3A5

4.20e-0521482ctd:C114289
DrugDEHP-CP

CYP3A5 AOC3

4.20e-0521482CID000127131
Drugtebuquine

KRT81 KRT83

4.20e-0521482CID000071991
Drug3,5-di-O-galloylquinic acid

KRT81 KRT83

4.20e-0521482CID000460896
Drug6 beta-hydroxytestosterone

CYP3A4 CYP3A5

4.20e-0521482ctd:C025591
DrugD-Myo-Inositol-1,4,5-Triphosphate

CYTH2 ITPKA

4.20e-0521482DB03401
DrugMADDS-NOH

CYP3A5 AOC3

4.20e-0521482CID000169449
DrugCQA 206-291

CYP3A4 CYP3A5

4.20e-0521482ctd:C059483
Drugfructus schizandrae, radix ginseng, radix ophiopogonis drug combination

CYP3A4 CYP3A5

4.20e-0521482ctd:C009252
Drugphenindione

CYP3A5 F2 TP53

4.27e-05111483CID000004760
DrugTroleandomycin

CYP3A7 CYP3A4 CYP3A5

4.27e-05111483ctd:D014217
DrugTicalopride

CYP3A7 CYP3A4 CYP3A5

4.27e-05111483CID000216236
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; HL60; HG-U133A

KCTD12 MYO1C CYP3A4 DIDO1 CRK EPM2AIP1 DHX15 R3HDM4

4.40e-0519614882019_DN
DrugAC1L1BIT

KRT81 KRT83 KRT86 AOC3 RASD1

4.44e-05601485CID000001457
DrugAH23848 hemicalcium salt hydrate; Down 200; 1uM; MCF7; HT_HG-U133A

OGT NUP98 PTK2 CRK R3HDM4 STIP1 DEDD TP53

4.57e-0519714886903_DN
Drug(+)-Arteannuin

CYP3A4 CYP3A5 KRT81 KRT83 IK

4.81e-05611485CID000002240
DrugPargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A

CYP3A4 KRT83 APBA1 ADAMTS13 RBCK1 TAOK2 DES MACF1

4.90e-0519914887016_UP
DrugAC1L9IK6

KRT16 NEFM DES NEFL

5.35e-05321484CID000445780
DrugAC1NRBWH

CYP3A5 PTK2 RASD1

5.67e-05121483CID005288678
DrugN-hydroxyamphetamine

CYP3A4 CYP3A5 AOC3

5.67e-05121483CID000065546
Drug2-Tbmbfd

CYP3A4 CYP3A5 AOC3

5.67e-05121483CID000126928
Drug9-anthraldehyde

CYP3A4 CYP3A5 AOC3

5.67e-05121483CID000069504
Drugatremon

CYP3A4 CYP3A5 GCDH HCK

6.06e-05331484CID000002741
Drug5'-sulfamoyladenosine

LAMB2 TAOK2 DES LNPK TP53

6.07e-05641485CID000097576
DrugAC1L18GM

CYP3A4 CYP3A5 AOC3

7.34e-05131483CID000000092
DrugUDP-4

NEFM DES NEFL

7.34e-05131483CID000126618
Drugarteether

CYP3A5 KRT81 KRT83

7.34e-05131483CID000072416
Drug4-chromanol

CYP3A4 CYP3A5 IK CDH17

7.67e-05351484CID000092890
Drug2,4-dichlorophenol

DCPS CYP3A5 TEC LNPK

7.67e-05351484CID000008449
Drug7-BFC

CYP3A7 CYP3A4 CYP3A5

9.30e-05141483CID000848780
Drug9-hydroxyellipticine

CYP3A4 CYP3A5 TP53

9.30e-05141483CID000091643
Drug2-amino-3,4-dimethylimidazo(4,5-f)quinoline

CYP3A7 CYP3A4 TP53

9.30e-05141483ctd:C036989
DrugHb 7

KRT81 KRT83 KRT85

9.30e-05141483CID000128180
Drugfarnesylamine

ZHX2 AOC3 RASD1

9.30e-05141483CID006449783
Drugtetrachlorophenol

CYP3A4 CYP3A5 TEC

9.30e-05141483CID000021013
Drugdasatinib

CYP3A4 PTK2 CRK LNPK HCK

9.34e-05701485CID003062316
DrugI5B1

KRT16 CYP3A5 DES AOC3

9.58e-05371484CID005487705
Drugimatinib

CYP3A4 CYP3A5 NUP98 TEC RYK PTK2 CRK DES RASD1 HCK TP53

1.21e-0443014811CID000005291
Drugchlorobenzene

DCPS CYP3A4 CYP3A5 MCC TEC

1.22e-04741485CID000007964
Drugerythralosamine

CYP3A4 CYP3A5

1.25e-0431482CID000352196
Drug5-hydroxytienilic acid

CYP3A5 AOC3

1.25e-0431482CID000146269
Drug3-methoxymorphinan

CYP3A4 CYP3A5

1.25e-0431482ctd:C028657
Drugdechloroethylcyclophosphamide

CYP3A4 CYP3A5

1.25e-0431482ctd:C064445
Drug6 beta-hydroxydexamethasone

CYP3A4 CYP3A5

1.25e-0431482CID000063050
Drugnitroxynil

CYP3A5 F2

1.25e-0431482CID000015532
DrugN-methylloline

CYP3A5 NEFL

1.25e-0431482CID000168027
Drug17-hydroxypregnenolone sulfate

CYP3A7 CYP3A4

1.25e-0431482CID000152971
Drugsulfonamide-3

KRT81 KRT83

1.25e-0431482CID009847197
Drug2-nitroso-1-phenylpropane

CYP3A5 AOC3

1.25e-0431482CID000124315
Drug1-hydroxymethylmidazolam

CYP3A4 CYP3A5

1.25e-0431482ctd:C040081
Drugtrichloroguaiacol

CYP3A5 TEC

1.25e-0431482CID000042115
DrugN-acetyl-S-pentachloro-1,3-butadienylcysteine

CYP3A4 CYP3A5

1.25e-0431482ctd:C049739
Drug3-methylcholanthrene

CYP3A7 CYP3A4 CYP3A5 PTK2 ITIH4 TAOK2 AOC3 TP53

1.39e-042311488CID000001674
DrugAC1L4VPA

CYP3A4 BAK1 F2

1.42e-04161483CID000164901
DrugTTMS

CYP3A4 CYP3A5 AOC3

1.42e-04161483CID000007215
Drugfurafylline

CYP3A7 CYP3A4 CYP3A5 AOC3

1.44e-04411484CID000003433
Drugbosutinib

TEC PTK2 CRK HCK

1.58e-04421484CID005328940
DiseaseMONILETHRIX

KRT81 KRT83 KRT86

1.09e-0731423158000
DiseaseBeaded hair

KRT81 KRT83 KRT86

1.09e-0731423cv:C0546966
Diseasemonilethrix (is_implicated_in)

KRT81 KRT83 KRT86

1.09e-0731423DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT83 KRT86

4.35e-0741423C0546966
Diseasetacrolimus measurement

CYP3A7 CYP3A4 CYP3A5

4.35e-0741423EFO_0008458
Diseasehair disease (is_implicated_in)

KRT81 KRT86

2.30e-0521422DOID:421 (is_implicated_in)
DiseaseCharcot-Marie-Tooth disease

AARS1 DRP2 NEFL SBF1

4.99e-05421424cv:C0007959
Diseasemetabolonic lactone sulfate measurement

CYP3A7 CYP3A4 CYP3A5

9.99e-05191423EFO_0800659
Diseaseprothrombin measurement

F2 CSTPP1

1.37e-0441422EFO_0020692
Diseaseestrone conjugate measurement

CYP3A7 CYP3A4

1.37e-0441422EFO_0007971
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.37e-0441422EFO_0020830
Diseasetauro-beta-muricholate measurement

CYP3A7 CYP3A4

2.28e-0451422EFO_0800213
Diseaseglyco-beta-muricholate measurement

CYP3A7 CYP3A4

2.28e-0451422EFO_0800569
DiseaseX-12063 measurement

CYP3A7 CYP3A4 CYP3A5 SUGCT PLCB2 CDH17

2.91e-041861426EFO_0021283
Diseaseintermittent claudication (biomarker_via_orthology)

BAK1 SIRT2

3.41e-0461422DOID:3669 (biomarker_via_orthology)
DiseaseParatuberculosis

F2 AOC3

3.41e-0461422C0030524
Diseasedehydroisoandrosterone sulfate DHEA-S measurement

CYP3A7 CYP3A4

3.41e-0461422EFO_0021119
Diseaseandrostenediol (3beta,17beta) monosulfate (1) measurement

CYP3A7 CYP3A4

3.41e-0461422EFO_0800294
DiseaseX-24574 measurement

CYP3A7 CYP3A4

4.75e-0471422EFO_0800897
Diseasenephrosis (implicated_via_orthology)

LAMB2 F2

4.75e-0471422DOID:2527 (implicated_via_orthology)
Diseasemicrocephaly (implicated_via_orthology)

AARS1 WDR81 ETNK2

4.89e-04321423DOID:10907 (implicated_via_orthology)
DiseaseAcute erythroleukemia - M6a subtype

NUP98 TP53

6.32e-0481422C2930975
DiseaseAcute myeloid leukemia FAB-M6

NUP98 TP53

6.32e-0481422C2930976
DiseaseAcute erythroleukemia - M6b subtype

NUP98 TP53

6.32e-0481422C2930977
DiseaseAcute erythroleukemia

NUP98 TP53

6.32e-0481422C2930974
Diseaseandrostenediol (3beta,17beta) disulfate (1) measurement

CYP3A7 CYP3A4

8.10e-0491422EFO_0800278
DiseaseSchizophrenia and related disorders

CYP3A5 IL1RAPL1

8.10e-0491422C0809983
DiseaseAsthma, Occupational

TENM3 CDH17

1.01e-03101422C0264423
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A7 CYP3A4

1.01e-03101422EFO_0022090
Diseasedisseminated intravascular coagulation (is_marker_for)

ADAMTS13 F2

1.01e-03101422DOID:11247 (is_marker_for)
Diseasesusceptibility to influenza measurement

NEFM NEFL

1.01e-03101422EFO_0803537
DiseaseB-lymphoblastic leukemia/lymphoma (is_implicated_in)

CYP3A5 TP53

1.01e-03101422DOID:0080630 (is_implicated_in)
Disease5alpha-androstan-3beta,17alpha-diol disulfate measurement

CYP3A7 CYP3A4

1.01e-03101422EFO_0800289
Diseasediffusing capacity of the lung for carbon monoxide

KRT86 CEP164 METTL13 PCDH7

1.21e-03961424EFO_0009369
DiseaseDNA repair protein RAD51 homolog 4 measurement

CYP3A7 CYP3A4

1.23e-03111422EFO_0801531
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A7 CYP3A4

1.23e-03111422EFO_0800295
Diseasetestosterone measurement

DOCK4 CYP3A7 GTF2A1L CYP3A4 NPEPPS DNAH2 WDR81 TTC27 RYK SUGCT MTHFD1 MACF1 CTPS1 TP53 SOAT1

1.27e-03127514215EFO_0004908
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

CYP3A7 CYP3A4

1.47e-03121422EFO_0800291
Diseaseage of onset of multiple sclerosis

LRRC56 CDH17

1.47e-03121422OBA_2001029
Diseasemyocardial infarction

DHX36 TDRD15 LAMB2 TENM3 GUCY1B1 PLCB2 CCDC63

1.58e-033501427EFO_0000612
DiseaseThrombosis

CYP3A5 ADAMTS13 F2

1.71e-03491423C0040053
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A7 CYP3A4

1.73e-03131422EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

1.73e-03131422EFO_0800284
Diseasecerebral amyloid angiopathy

KCTD12 MCC NEDD1

1.92e-03511423EFO_0006790
Diseaseestradiol measurement

CYP3A7 CYP3A4 EHD3 CELSR1

2.00e-031101424EFO_0004697
Diseasecongenital hypothyroidism (implicated_via_orthology)

NEFM NEFL

2.01e-03141422DOID:0050328 (implicated_via_orthology)
DiseaseX-21470 measurement

CYP3A7 CYP3A4

2.01e-03141422EFO_0800817
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

CYP3A7 CYP3A4

2.01e-03141422EFO_0800283
DiseaseHereditary Breast and Ovarian Cancer Syndrome

RAD50 TP53

2.01e-03141422C0677776
DiseaseNephrosis

F2 DES

2.32e-03151422C0027720
Disease16a-hydroxy DHEA 3-sulfate measurement

CYP3A7 CYP3A4

2.32e-03151422EFO_0800301
DiseaseX-21410 measurement

CYP3A7 CYP3A4

2.64e-03161422EFO_0800813
DiseasePolyposis, Adenomatous Intestinal

MCC ITIH4

2.64e-03161422C2713442
DiseaseFamilial Intestinal Polyposis

MCC ITIH4

2.64e-03161422C2713443
Diseaseandro steroid monosulfate C19H28O6S (1) measurement

CYP3A7 CYP3A4

2.64e-03161422EFO_0800305
Diseasepulse pressure measurement

TDRD15 ATP8B4 MYO1C TEC CCDC77 CEP164 RYK CRK DHX15 CDCA7 SUGCT IK TEC TP53 CDH17

2.96e-03139214215EFO_0005763
Diseasepre-malignant neoplasm (biomarker_via_orthology)

SUV39H1 TP53

2.98e-03171422DOID:0060071 (biomarker_via_orthology)
DiseaseAdenomatous Polyposis Coli

MCC ITIH4

2.98e-03171422C0032580
DiseaseCharcot-Marie-Tooth disease type 2

AARS1 NEFL

2.98e-03171422cv:C0270914
Diseaseischemia (biomarker_via_orthology)

PTK2 TP53

3.35e-03181422DOID:326 (biomarker_via_orthology)
DiseaseDisorder of organic acid metabolism

GCDH PCCA

3.35e-03181422cv:C1263739
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

3.35e-03181422EFO_0800288
Diseasecystathionine measurement

TEC TEC

3.73e-03191422EFO_0010474
Diseasep-tau:beta-amyloid 1-42 ratio measurement

KRT78 UNC5B

3.73e-03191422EFO_0007709
Diseaseetiocholanolone glucuronide measurement

CYP3A7 CYP3A4

3.73e-03191422EFO_0800362
Diseaseandrosterone glucuronide measurement

CYP3A7 CYP3A4

4.13e-03201422EFO_0800317
Diseaseviral load

CYP3A4 RAP1GAP2 SUGCT CSTPP1

4.29e-031361424EFO_0010125
Diseasedehydroepiandrosterone sulphate measurement

DOCK4 CYP3A7 CYP3A4

4.35e-03681423EFO_0007001

Protein segments in the cluster

PeptideGeneStartEntry
EVLRYDDRAIGELLS

SUGCT

421

Q9HAC7
RQLAIIGDDINRRYD

BAK1

76

Q16611
NDRVALYIAREGKEE

AACS

111

Q86V21
SGVNYLILDDDDRER

BCAR3

471

O75815
QYGDVLVRNLRREAE

CYP3A5

151

P20815
LRGEDQEVELVVDYI

ALDH1L2

416

Q3SY69
YEALERRRILEVEGF

CCDC77

406

Q9BR77
DERIAGLYEEIERDL

ATP8B4

626

Q8TF62
RVRENLEVGYEVLTI

CELSR1

361

Q9NYQ6
VDEEDYELGRQKLLR

DEDD

296

O75618
LERYGVIILDEAHER

DHX15

251

O43143
QDLRLIRETGDDYRN

DCPS

146

Q96C86
ARYEIVVEARDAQGL

CDH5

221

P33151
LIESAEELIRDGRYT

DNAJC3

271

Q13217
LEDGRVEYRVALTED

ADAMTS13

621

Q76LX8
DVRFQGERLVYEISL

AOC3

351

Q16853
GVILRQEEAEYVRAL

CRK

126

P46108
IERGLRVIEITIYED

GOLGA7

116

Q7Z5G4
TVLDGNLIIRYDVDR

ITIH4

231

Q14624
AERVLRYLVEVEELA

PDRG1

6

Q9NUG6
SGEEQERVLRYLEDE

R3HDM4

126

Q96D70
TARELVAEALERYGL

RASIP1

171

Q5U651
VREPELEDLTRYDVG

RANBP2

411

P49792
FYREVDQREIEQLVG

RASD1

151

Q9Y272
RGQDIEYIEIRSDAD

RAD50

1156

Q92878
ELEDLARYDVGAIRA

RGPD5

416

Q99666
ELEDLARYDVGAIRA

RGPD8

416

O14715
IYEDVIRGCLLQRID

NIBAN3

571

Q86XR2
ERLIGRYDEEVVKEL

SPAG9

36

O60271
DYREVEKLLRAVADG

ANKRD27

666

Q96NW4
DDELEGRRIAFILYL

OGFOD1

156

Q8N543
LYEVGRQRLAEDEDE

DCAF1

1386

Q9Y4B6
DRLADINYEGRLEAV

NUP98

841

P52948
GVVDLDLDELNVYAR

MB21D2

96

Q8IYB1
YSVNEGLVAEIERLR

NEDD1

636

Q8NHV4
EDEGRYRCELINGIE

HAPLN2

121

Q9GZV7
RYEAEITALERERGV

DNAAF2

51

Q9NVR5
LDIEIATYRRLLEGE

KRT85

416

P78386
VQGRDDALERRINEY

MMRN1

706

Q13201
ERARLAGEEEALRQY

RBCK1

236

Q9BYM8
IEIATYRRLLEGEEQ

KRT86

401

O43790
DVLYEEVEELRLVLG

FREM2

2206

Q5SZK8
QYGDVLVRNLRREAE

CYP3A4

151

P08684
ELYRSLGDVLRDVDA

EIF2B5

126

Q13144
VRVYGERTELLVDRE

ETNK2

111

Q9NVF9
ETRRLGDVAEVLYQA

PLXNB3

141

Q9ULL4
LLIREVREDDIGNYT

IL1RAPL1

201

Q9NZN1
IVKGALDREQRDSYE

PCDH7

261

O60245
QLVEARGRYEELCIV

PFKL

506

P17858
YRGLRGDDAINEVLE

HRH2

256

P25021
EQEIATYRRLLEGED

KRT16

411

P08779
LDVEIATYRRLLEGE

KRT78

406

Q8N1N4
SYIRDRIEEIRLEGN

OGN

261

P20774
RLQELEGTYEENERA

LAMB2

1751

P55268
EELIREIAGLVRRYD

GDPD3

156

Q7L5L3
EIAGLVRRYDRNEIT

GDPD3

161

Q7L5L3
LDEEGQFLVRIIYDD

GUCY1B1

31

Q02153
RVEGNLRVEYLDDRN

TP53

196

P04637
DAEEAVRIAREIGYP

PCCA

201

P05165
EGALDREIRAEYNIT

PCDHB10

406

Q9UN67
EQLELTLGRVEDFYR

MACF1

5226

Q9UPN3
NTADRIIRVYDGREI

RBBP5

216

Q15291
EFVQGDEEVLRRYLN

ITPKA

361

P23677
ERIELGLLYEEKGER

SBF1

1531

O95248
EDLTRALGDYARVEQ

PRR35

406

P0CG20
TLIYRRVLAEDAGEI

OBSCN

2256

Q5VST9
ENLRDGDRYILRQEG

OBSCN

3486

Q5VST9
ELEDLARYDVGAIRA

RGPD3

416

A6NKT7
IDRLQGTTIREEDEY

MCC

96

P23508
GLARVIEDNEYTARE

HCK

401

P08631
ETYRRILEVEGAEAE

CCDC63

461

Q8NA47
RRVYDITNVLDGIDL

E2F6

101

O75461
LQLLHGDIEQIRREY

DOCK4

361

Q8N1I0
LLENREDISQYGIAR

CSTPP1

31

Q9H6J7
VAYGLLARELERVDS

GCDH

121

Q92947
ERYVADGERAALVER

EPM2AIP1

66

Q7L775
GEAAYLRVISEEREL

FAM83C

56

Q9BQN1
VALIRYIVLEEEDGA

DHX36

476

Q9H2U1
LDRYHRIIEIEGNRL

BFSP1

306

Q12934
IGDYLGEREELNLAV

CYTH2

111

Q99418
SGYQDNIARLEEEIR

DES

361

P17661
EARGRLLERNGEDYI

DIDO1

301

Q9BTC0
ELDARDGLRLYEQER

APBA1

206

Q02410
YEIQIRVLREFGLAD

BTBD7

686

Q9P203
EDIRENEARQLGVGY

CCDC174

236

Q6PII3
EDLVLELIFGYRGRD

EML5

1361

Q05BV3
RIDFELREGLVESRY

DDHD1

846

Q8NEL9
QYGDVLVRNLRREAE

CYP3A7

151

P24462
LLYVRRIEGEVNEIL

METTL13

636

Q8N6R0
EEREYVVLIRINDGG

CDH17

736

Q12864
EEGRKRIDSYLREIE

DNAH2

2331

Q9P225
QLIEDIVRDGRLYAS

SCUBE1

916

Q8IWY4
QELIEDIVRDGRLYA

SCUBE2

926

Q9NQ36
EQLVEDIVRDGRLYA

SCUBE3

921

Q8IX30
LYLSEDEVRRLIGLD

RYK

66

P34925
LYSEVAEERERLGQQ

CEP131

796

Q9UPN4
EAEYFELPELVRRLG

KCTD12

116

Q96CX2
IYVEAEQVEDDRLLR

NPEPPS

506

P55786
REIGLLSEEVELYGE

MTHFD1

336

P11586
LTALYERLEEERGIL

DRP2

451

Q13474
VIDGVNYLIDCERRL

CKMT1A

386

P12532
IEIATYRRLLEGEEQ

KRT83

406

P78385
EQGLIDLAIDTYRRA

OGT

271

O15294
ELEDLARYDVGAIRA

RGPD4

416

Q7Z3J3
TLVVDYIDEGRLVLE

SOAT1

156

P35610
EEAEGIEYLRVILRS

RAP1GAP2

186

Q684P5
GEYLRLSREIQEAAA

TDRD6

41

O60522
IEVGRENREDYRQIA

STIP1

286

P31948
NELYTVLLIDRGEEL

TDRD15

86

B5MCY1
HDLRLERGQEYLILE

TEC

196

P42680
QRDRLGEQLVEEYLS

LRRC56

41

Q8IYG6
LEEQYLGLALDVDRI

NBPF10

1226

Q6P3W6
LEEQYLGLALDVDRI

NBPF10

2446

Q6P3W6
LEEQYLGLALDVDRI

NBPF19

711

A0A087WUL8
LEEQYLGLALDVDRI

NBPF19

1931

A0A087WUL8
LEEQYLGLALDVDRI

NBPF19

3151

A0A087WUL8
RESYEELLQLEDRLG

RNF165

236

Q6ZSG1
STRDYEIQRERIELG

PTK2

411

Q05397
LLEEQGVVDYFLRRL

CTPS1

256

P17812
ERLLDELTLEGVARY

SIRT2

56

Q8IXJ6
EEEAGLLRRQRQYFE

TAOK2

626

Q9UL54
ERAQLEDGRFVYRLL

TEAD2

361

Q15562
AAEGRYEVLRELLEA

SOWAHD

121

A6NJG2
LKEEVGSRIADRVYD

NDUFAF5

71

Q5TEU4
PEELGARILIQERYE

SF3A1

301

Q15459
LVNNLAEIYGRIERE

EHD3

331

Q9NZN3
EEVDLYRQLSLAGRV

FAM83F

296

Q8NEG4
EIITSEEAERRGQIY

SUV39H1

276

O43463
LRNRYGEEVRDALLD

CDCA7

301

Q9BWT1
LRIGDQLVLEEDYDE

CEP164

6

Q9UPV0
SIREVLYRGNADEEL

TRIM52

81

Q96A61
EDYLRHEIGELQQRL

TMF1

736

P82094
LEGELEELRQDRTLY

nan

431

Q6ZTK2
DIYAIEELRARGLEV

AARS1

466

P49588
YRSVIEDVIEGVRNL

GTF2A1L

11

Q9UNN4
REAPEELLAYEGVRA

TBL3

741

Q12788
ALERELLEDYRFGRQ

YJEFN3

76

A6XGL0
DVQYRLDEDGFLRQR

TENM3

2186

Q9P273
ERRRQEAEELEGYCI

TSKS

176

Q9UJT2
RRDGVNKDYEETELI

IK

106

Q13123
EVLELERTLGGYLVE

UNC5B

726

Q8IZJ1
RLELELLRQGEEQYE

PLCB2

986

Q00722
DAEVYRLIEVTGLAR

ZHX2

466

Q9Y6X8
GEEVVVLLEYLERQL

ZKSCAN4

121

Q969J2
TERELLESYIDGRIV

F2

351

P00734
YVAQLILDVRREGDV

TTC27

281

Q6P3X3
RLELGEELYRLQFID

WDR87

281

Q6ZQQ6
LYQARRVEDEAQGRE

WDR81

886

Q562E7
REVYRILQEEGIDLP

PPIP5K1

146

Q6PFW1
AYETREDIIRLVGEL

TRPV5

376

Q9NQA5
IEIATYRRLLEGEEQ

KRT81

401

Q14533
RERGALDRIVEYLVG

LNPK

251

Q9C0E8
GRIREALEVYRQLSE

LONRF3

81

Q496Y0
YQLLEGGEEETLRRL

MYO1C

241

O00159
GLEETLRNLQARYEE

NEFL

166

P07196
LGDAYDQEIRELRAT

NEFM

146

P07197