Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled photoreceptor activity	OPN1LW OPN1MW OPN1MW2 OPN1MW3	1.72e-06	15	122	4	GO:0008020
GeneOntologyMolecularFunction	photoreceptor activity	OPN1LW OPN1MW OPN1MW2 OPN1MW3	2.97e-06	17	122	4	GO:0009881
GeneOntologyBiologicalProcess	sensory perception	SOX2 CYP4V2 ANO1 OPN1LW POMGNT1 OPN1MW SIX3 PKHD1L1 OR4L1 OPN1MW2 TAS2R42 OPN1MW3 TAS2R7 TAS2R14 LOXHD1 SCN8A OR10A6 GPR171 USH2A EPAS1	5.32e-06	1072	123	20	GO:0007600
GeneOntologyBiologicalProcess	seminiferous tubule development	BRIP1 RAD21L1 JMJD1C WDR48	9.77e-06	23	123	4	GO:0072520
GeneOntologyBiologicalProcess	visual perception	CYP4V2 OPN1LW OPN1MW SIX3 OPN1MW2 OPN1MW3 USH2A EPAS1	7.25e-05	230	123	8	GO:0007601
GeneOntologyBiologicalProcess	sensory perception of light stimulus	CYP4V2 OPN1LW OPN1MW SIX3 OPN1MW2 OPN1MW3 USH2A EPAS1	7.94e-05	233	123	8	GO:0050953
GeneOntologyBiologicalProcess	cell fate specification	SOX1 SOX2 TBX21 CHD4 EOMES TBR1	9.57e-05	123	123	6	GO:0001708
GeneOntologyCellularComponent	photoreceptor disc membrane	OPN1LW OPN1MW OPN1MW2 OPN1MW3	1.75e-05	26	127	4	GO:0097381
Domain	Opsin_red/grn	OPN1LW OPN1MW OPN1MW3	2.86e-07	3	124	3	IPR000378
Domain	RIBOSOMAL_S4E	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	PS00528
Domain	Ribosomal_S4e_central_region	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	IPR013845
Domain	Ribosomal_S4e_N	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	IPR013843
Domain	Ribosomal_S4e_central	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	PD002667
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	PF16121
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	IPR032277
Domain	Ribosomal_S4e_N_CS	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	IPR018199
Domain	RS4NT	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	PF08071
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	IPR000876
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	2.86e-07	3	124	3	PF00900
Domain	S4	RPS4Y2 RPS4X RPS4Y1	2.83e-06	5	124	3	SM00363
Domain	S4	RPS4Y2 RPS4X RPS4Y1	2.83e-06	5	124	3	PS50889
Domain	S4_RNA-bd	RPS4Y2 RPS4X RPS4Y1	5.63e-06	6	124	3	IPR002942
Domain	OPSIN	OPN1LW OPN1MW OPN1MW3	3.31e-05	10	124	3	PS00238
Domain	T-box_assoc	EOMES TBR1	4.37e-05	2	124	2	PF16176
Domain	T-box_assoc	EOMES TBR1	4.37e-05	2	124	2	IPR032385
Domain	KOW	RPS4Y2 RPS4X RPS4Y1	4.53e-05	11	124	3	IPR005824
Domain	KOW	RPS4Y2 RPS4X RPS4Y1	4.53e-05	11	124	3	PF00467
Domain	Opsin	OPN1LW OPN1MW OPN1MW3	4.53e-05	11	124	3	IPR001760
Domain	CHD_N	CHD4 CHD5	1.31e-04	3	124	2	IPR012958
Domain	CHD_C2	CHD4 CHD5	1.31e-04	3	124	2	IPR012957
Domain	CHDCT2	CHD4 CHD5	1.31e-04	3	124	2	PF08074
Domain	CHDNT	CHD4 CHD5	1.31e-04	3	124	2	PF08073
Domain	DUF1086	CHD4 CHD5	1.31e-04	3	124	2	IPR009462
Domain	DUF1087	CHD4 CHD5	1.31e-04	3	124	2	IPR009463
Domain	DUF1087	CHD4 CHD5	1.31e-04	3	124	2	PF06465
Domain	DUF1086	CHD4 CHD5	1.31e-04	3	124	2	PF06461
Domain	DUF1087	CHD4 CHD5	1.31e-04	3	124	2	SM01147
Domain	DUF1086	CHD4 CHD5	1.31e-04	3	124	2	SM01146
Domain	TF_T-box	TBX21 EOMES TBR1	1.81e-04	17	124	3	IPR001699
Domain	TBOX	TBX21 EOMES TBR1	1.81e-04	17	124	3	SM00425
Domain	TF_T-box_CS	TBX21 EOMES TBR1	1.81e-04	17	124	3	IPR018186
Domain	-	TBX21 EOMES TBR1	1.81e-04	17	124	3	2.60.40.820
Domain	TBOX_3	TBX21 EOMES TBR1	1.81e-04	17	124	3	PS50252
Domain	T-box	TBX21 EOMES TBR1	1.81e-04	17	124	3	PF00907
Domain	TBOX_1	TBX21 EOMES TBR1	1.81e-04	17	124	3	PS01283
Domain	TBOX_2	TBX21 EOMES TBR1	1.81e-04	17	124	3	PS01264
Domain	TRPM_tetra	TRPM7 TRPM3	2.60e-04	4	124	2	PF16519
Domain	S4	RPS4X RPS4Y1	2.60e-04	4	124	2	PF01479
Domain	TRPM_tetra	TRPM7 TRPM3	2.60e-04	4	124	2	IPR032415
Domain	SOXp	SOX1 SOX2	4.32e-04	5	124	2	PF12336
Domain	SOX_fam	SOX1 SOX2	4.32e-04	5	124	2	IPR022097
Domain	ENTH	EPN2 EPN1	6.45e-04	6	124	2	PF01417
Domain	TAS2R	TAS2R42 TAS2R7 TAS2R14	6.64e-04	26	124	3	PF05296
Domain	T2R	TAS2R42 TAS2R7 TAS2R14	6.64e-04	26	124	3	IPR007960
Domain	HMG_box_dom	SOX1 SOX2 CHD4 CHD5	9.17e-04	65	124	4	IPR009071
Domain	Ion_trans_dom	TRPM7 TRPM3 SCN7A SCN8A TRPV3	9.81e-04	114	124	5	IPR005821
Domain	Ion_trans	TRPM7 TRPM3 SCN7A SCN8A TRPV3	9.81e-04	114	124	5	PF00520
Domain	SNF2_N	CHD4 CHD5 HLTF	1.23e-03	32	124	3	IPR000330
Domain	SNF2_N	CHD4 CHD5 HLTF	1.23e-03	32	124	3	PF00176
Domain	TCEAL1	TCEAL3 TCEAL6	1.53e-03	9	124	2	IPR010370
Domain	ENTH	EPN2 EPN1	1.53e-03	9	124	2	PS50942
Domain	ENTH	EPN2 EPN1	1.53e-03	9	124	2	SM00273
Domain	DNA/RNA_helicase_DEAH_CS	BRIP1 CHD4 CHD5	1.60e-03	35	124	3	IPR002464
Domain	Na_channel_asu	SCN7A SCN8A	1.90e-03	10	124	2	IPR001696
Domain	Na_trans_assoc	SCN7A SCN8A	1.90e-03	10	124	2	IPR010526
Domain	ENTH	EPN2 EPN1	1.90e-03	10	124	2	IPR013809
Domain	Na_trans_assoc	SCN7A SCN8A	1.90e-03	10	124	2	PF06512
Domain	DEAH_ATP_HELICASE	BRIP1 CHD4 CHD5	2.03e-03	38	124	3	PS00690
Domain	BEX	TCEAL3 TCEAL6	3.78e-03	14	124	2	PF04538
Domain	TF_A-like/BEX	TCEAL3 TCEAL6	3.78e-03	14	124	2	IPR021156
Domain	EMP24_GP25L	TMED4 SEC14L4	4.34e-03	15	124	2	PF01105
Domain	Laminin_N	NTN4 USH2A	4.94e-03	16	124	2	IPR008211
Domain	LamNT	NTN4 USH2A	4.94e-03	16	124	2	SM00136
Domain	LAMININ_NTER	NTN4 USH2A	4.94e-03	16	124	2	PS51117
Domain	Laminin_N	NTN4 USH2A	4.94e-03	16	124	2	PF00055
Domain	p53-like_TF_DNA-bd	TBX21 EOMES TBR1	5.25e-03	53	124	3	IPR008967
Domain	-	SOX1 SOX2 CHD5	5.83e-03	55	124	3	1.10.30.10
Domain	DEXDc	BRIP1 CHD4 CHD5 HLTF	6.02e-03	109	124	4	SM00487
Domain	Helicase_ATP-bd	BRIP1 CHD4 CHD5 HLTF	6.22e-03	110	124	4	IPR014001
Domain	UIM	EPN2 EPN1	6.24e-03	18	124	2	PF02809
Pathway	REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION	OPN1LW OPN1MW2 OPN1MW3	1.57e-05	8	94	3	MM14880
Pathway	REACTOME_OPSINS	OPN1LW OPN1MW2 OPN1MW3	3.33e-05	10	94	3	MM15063
Pathway	REACTOME_TRP_CHANNELS	RIPK1 TRPM7 TRPM3 TRPV3	3.36e-05	28	94	4	MM14943
Pathway	REACTOME_TRP_CHANNELS	RIPK1 TRPM7 TRPM3 TRPV3	3.36e-05	28	94	4	M27241
Pathway	REACTOME_SENSORY_PERCEPTION	CYP4V2 OPN1LW OR4L1 OPN1MW2 OPN1MW3 TAS2R7 TAS2R14 OR10A6	3.89e-05	190	94	8	MM15687
Pubmed	A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.	SOX2 CHD4 EOMES CHD5 TBR1 CUX1	2.64e-11	17	128	6	27806305
Pubmed	Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.	SOX2 TRPM7 ANO1 EOMES TRPM3 TRPV3	3.95e-11	18	128	6	31911949
Pubmed	Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.	OPN1LW OPN1MW OPN1MW2 OPN1MW3	1.75e-10	4	128	4	29386880
Pubmed	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.	OPN1LW OPN1MW OPN1MW2 OPN1MW3	8.73e-10	5	128	4	2937147
Pubmed	Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.	SOX1 SOX2 JMJD1C EOMES TBR1 CUX1	2.73e-09	34	128	6	31569049
Pubmed	Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.	SOX2 TBX21 EOMES TBR1 CUX1	5.15e-09	18	128	5	27320921
Pubmed	Localization of the mdx mutation within the mouse dystrophin gene.	CYBB OPN1LW OPN1MW2 OPN1MW3	1.21e-08	8	128	4	2903046
Pubmed	TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex.	SOX2 EOMES TBR1 CUX1	1.21e-08	8	128	4	35159260
Pubmed	DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.	SOX1 SOX2 EOMES TBR1 CUX1	1.99e-08	23	128	5	30329130
Pubmed	The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.	SOX2 EOMES TBR1 CUX1	2.17e-08	9	128	4	25972180
Pubmed	Evolutionarily conserved anterior expansion of the central nervous system promoted by a common PcG-Hox program.	SOX1 SOX2 EOMES TBR1	2.17e-08	9	128	4	29530878
Pubmed	Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism.	SOX2 EOMES TBR1 CUX1	3.61e-08	10	128	4	31740755
Pubmed	ATF5 deficiency causes abnormal cortical development.	SOX2 EOMES TBR1 CUX1	3.61e-08	10	128	4	33790322
Pubmed	Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.	CYBB OPN1LW OPN1MW2 OPN1MW3	3.61e-08	10	128	4	1973380
Pubmed	Multiple hypothalamic cell populations encoding distinct visual information.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	21224225
Pubmed	Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	36216501
Pubmed	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.	RPS4Y2 RPS4X RPS4Y1	4.87e-08	3	128	3	2124517
Pubmed	Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	34111401
Pubmed	Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.	RPS4Y2 RPS4X RPS4Y1	4.87e-08	3	128	3	8187552
Pubmed	Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.	RPS4Y2 RPS4X RPS4Y1	4.87e-08	3	128	3	8808278
Pubmed	Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	28751656
Pubmed	The molecular genetics and evolution of red and green color vision in vertebrates.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	11545071
Pubmed	Co-expression of murine opsins facilitates identifying the site of cone adaptation.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	12511072
Pubmed	Molecular determinants of human red/green color discrimination.	OPN1LW OPN1MW OPN1MW2	4.87e-08	3	128	3	8185948
Pubmed	X-linked cone dystrophy caused by mutation of the red and green cone opsins.	OPN1LW OPN1MW OPN1MW2	4.87e-08	3	128	3	20579627
Pubmed	Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	38410159
Pubmed	Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	23350963
Pubmed	Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	20471354
Pubmed	Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis.	TBX21 EOMES TBR1	4.87e-08	3	128	3	12128215
Pubmed	Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	10567724
Pubmed	Inactivation of the Rps4 gene on the mouse X chromosome.	RPS4Y2 RPS4X RPS4Y1	4.87e-08	3	128	3	1783379
Pubmed	Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	14500905
Pubmed	Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	31469404
Pubmed	Mechanisms of spectral tuning in the mouse green cone pigment.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	9238068
Pubmed	Emergence of novel color vision in mice engineered to express a human cone photopigment.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	17379811
Pubmed	The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.	OPN1LW OPN1MW2 OPN1MW3	4.87e-08	3	128	3	7958444
Pubmed	Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes.	CYBB OPN1LW OPN1MW2 OPN1MW3	5.66e-08	11	128	4	1572636
Pubmed	Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes.	SOX2 EOMES TBR1 CUX1	5.66e-08	11	128	4	32115408
Pubmed	A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.	SOX2 EOMES TBR1 CUX1	5.66e-08	11	128	4	34587386
Pubmed	In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells.	SOX2 EOMES TBR1 CUX1	5.66e-08	11	128	4	25070536
Pubmed	Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.	SOX2 EOMES TBR1 CUX1	5.66e-08	11	128	4	34943873
Pubmed	The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.	SOX1 SOX2 EOMES TBR1 CUX1	5.73e-08	28	128	5	18794345
Pubmed	Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome.	CYBB OPN1LW OPN1MW2 OPN1MW3	8.47e-08	12	128	4	1679744
Pubmed	Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease.	CYBB OPN1LW OPN1MW2 OPN1MW3	8.47e-08	12	128	4	2561974
Pubmed	Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder.	SOX2 EOMES TBR1 CUX1	8.47e-08	12	128	4	29294103
Pubmed	Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis.	SOX2 EOMES TBR1 CUX1	1.22e-07	13	128	4	31801076
Pubmed	Lrig1 regulates cell fate specification of glutamatergic neurons via FGF-driven Jak2/Stat3 signaling in cortical progenitors.	SOX2 EOMES TBR1 CUX1	1.22e-07	13	128	4	39250533
Pubmed	G protein-coupled receptors participate in cytokinesis.	OPN1LW RXFP3 OPN1MW OPN1MW2	1.22e-07	13	128	4	22888021
Pubmed	Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain.	SOX1 EOMES TBR1 CUX1	1.22e-07	13	128	4	24927931
Pubmed	NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients.	SOX2 EOMES TBR1 CUX1	1.22e-07	13	128	4	32484994
Pubmed	Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.	SOX2 EOMES TBR1 CUX1	1.70e-07	14	128	4	27974163
Pubmed	Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice.	SOX2 EOMES TBR1 CUX1	1.70e-07	14	128	4	33203851
Pubmed	Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors.	SOX2 EOMES TBR1 CUX1	1.70e-07	14	128	4	20460369
Pubmed	NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesis.	SOX2 EOMES TBR1 CUX1	1.70e-07	14	128	4	31816056
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	CYBB OPN1LW OPN1MW2 OPN1MW3	1.70e-07	14	128	4	8432533
Pubmed	Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	28103478
Pubmed	Molecular biology of the visual pigments.	OPN1LW OPN1MW OPN1MW2	1.94e-07	4	128	3	3303660
Pubmed	Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.	RPS4Y2 RPS4X RPS4Y1	1.94e-07	4	128	3	8139551
Pubmed	Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	26438865
Pubmed	Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	17249565
Pubmed	Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	38060327
Pubmed	Contribution of M-opsin-based color vision to refractive development in mice.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	34126082
Pubmed	Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	31461375
Pubmed	Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	8088841
Pubmed	Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	31846668
Pubmed	Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	16567464
Pubmed	S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	24801621
Pubmed	Melanopsin Contributions to the Representation of Images in the Early Visual System.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	28528909
Pubmed	Melanopsin-driven light adaptation in mouse vision.	OPN1LW OPN1MW2 OPN1MW3	1.94e-07	4	128	3	25308073
Pubmed	Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex.	SOX2 EOMES TBR1 CUX1	2.32e-07	15	128	4	37348506
Pubmed	Loss of Lgl1 Disrupts the Radial Glial Fiber-guided Cortical Neuronal Migration and Causes Subcortical Band Heterotopia in Mice.	SOX2 EOMES TBR1 CUX1	2.32e-07	15	128	4	30597194
Pubmed	YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development.	SOX2 EOMES TBR1 CUX1	2.32e-07	15	128	4	34419458
Pubmed	Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development.	OPN1LW SIX3 OPN1MW2 OPN1MW3	2.32e-07	15	128	4	11468275
Pubmed	Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.	SOX2 EOMES TBR1 CUX1	3.08e-07	16	128	4	19948250
Pubmed	Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus.	SOX2 EOMES TBR1 CUX1	3.08e-07	16	128	4	34815315
Pubmed	MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex.	SOX2 EOMES TBR1 CUX1	3.08e-07	16	128	4	23623502
Pubmed	Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development.	SOX2 EOMES TBR1 CUX1	3.08e-07	16	128	4	35379703
Pubmed	SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.	SOX2 EOMES TBR1 CUX1	3.08e-07	16	128	4	31515109
Pubmed	mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.	SOX2 OPN1LW OPN1MW2 OPN1MW3 EPAS1	3.70e-07	40	128	5	34677125
Pubmed	Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons.	SOX2 EOMES TBR1 CUX1	4.01e-07	17	128	4	21976703
Pubmed	Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex.	SOX2 EOMES TBR1 CUX1	4.01e-07	17	128	4	26740489
Pubmed	Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	26818794
Pubmed	A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	22090509
Pubmed	Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8+ T cells.	TBX21 EOMES TBR1	4.84e-07	5	128	3	10970091
Pubmed	Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	27033727
Pubmed	Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.	RPS4Y2 RPS4X RPS4Y1	4.84e-07	5	128	3	9562962
Pubmed	The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	11055434
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	RPS4Y2 RPS4X RPS4Y1	4.84e-07	5	128	3	7681608
Pubmed	Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	36631163
Pubmed	A common integration locus in type B retrovirus-induced thymic lymphomas.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	1333116
Pubmed	Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	10723722
Pubmed	Melanopsin-based brightness discrimination in mice and humans.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	22633808
Pubmed	Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	24058409
Pubmed	Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.	OPN1LW OPN1MW2 OPN1MW3	4.84e-07	5	128	3	34099749
Pubmed	Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation.	SOX2 EOMES TBR1 CUX1	5.15e-07	18	128	4	23817546
Pubmed	Smad4 and Trim33/Tif1γ redundantly regulate neural stem cells in the developing cortex.	SOX2 EOMES TBR1 CUX1	5.15e-07	18	128	4	23765158
Pubmed	PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.	SOX2 EOMES TBR1 CUX1	6.50e-07	19	128	4	33597191
Pubmed	Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus.	SOX2 EOMES TBR1 CUX1	6.50e-07	19	128	4	35575074
Pubmed	The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis.	SOX2 EOMES TBR1 CUX1	8.10e-07	20	128	4	35931079
Pubmed	Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.	SOX2 EOMES TBR1 CUX1	8.10e-07	20	128	4	26802325
Cytoband	12p13	CHD4 TAS2R42 TAS2R7 TAS2R14 KLRC1	1.04e-06	64	128	5	12p13
GeneFamily	Opsin receptors	OPN1LW OPN1MW OPN1MW2 OPN1MW3	2.11e-07	11	93	4	215
GeneFamily	T-boxes	TBX21 EOMES TBR1	1.02e-04	18	93	3	766
GeneFamily	Transient receptor potential cation channels	TRPM7 TRPM3 TRPV3	3.93e-04	28	93	3	249
GeneFamily	S ribosomal proteins	RPS4Y2 RPS4X RPS4Y1	7.02e-04	34	93	3	728
GeneFamily	Transcription elongation factor A like family	TCEAL3 TCEAL6	9.20e-04	9	93	2	1216
GeneFamily	Taste 2 receptors	TAS2R42 TAS2R7 TAS2R14	1.05e-03	39	93	3	1162
GeneFamily	PHD finger proteins\|NuRD complex	CHD4 CHD5	1.67e-03	12	93	2	1305
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	RPS4Y1 UGT2B17 PUM3	2.29e-03	51	93	3	870
GeneFamily	SRY-boxes	SOX1 SOX2	4.23e-03	19	93	2	757
Coexpression	GSE30083_SP3_VS_SP4_THYMOCYTE_DN	CYBB CYP4V2 RIPK1 TBX21 ANKH FAAH EOMES BANK1	5.48e-06	200	125	8	M5037
Coexpression	TABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING	RPS4Y2 RPS4X RPS4Y1	8.71e-06	9	125	3	MM3821
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PKHD1L1 DLC1 TRPM3 SERPINE1 PDE7B EPAS1 GULP1	1.14e-06	189	126	7	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.23e-06	191	126	7	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.23e-06	191	126	7	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.23e-06	191	126	7	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	Control-Lymphoid_T/NK-NK_CD56bright\|Control / Disease group, lineage and cell class	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.23e-06	191	126	7	e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.23e-06	191	126	7	c023ca893ceae19b54967096f6e2588dc39fa268
ToppCell	normal-na-Lymphocytic_NK-NK_bright-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.36e-06	194	126	7	dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.36e-06	194	126	7	afa8d29924719af3bc5f48f22cf66d5e8f9e3e37
ToppCell	normal-na-Lymphocytic_NK-NK_bright\|normal / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 SYNE1 TBX21 EOMES AGK PLA2G6 KLRC1	1.36e-06	194	126	7	8c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL12RB2 RPS4X TBX21 EOMES AGK PDE7B KLRC1	1.41e-06	195	126	7	234666fb7a1fd7e33bb7e54fd4004649ce22de70
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL12RB2 RPS4X TBX21 EOMES AGK PDE7B KLRC1	1.41e-06	195	126	7	f0fb039f3d2e36acb258afb8b6d2fed20c395c36
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL12RB2 RPS4X TBX21 EOMES AGK PDE7B KLRC1	1.41e-06	195	126	7	c7743d8c57584d29cca69c6405f1df6718174582
ToppCell	Severe-Lymphoid-NK-NK\|Severe / Condition, Lineage, Cell class and cell subclass	IL12RB2 RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	1.51e-06	197	126	7	d5b94f9f73e9d050245841b19b046242a32c6258
ToppCell	Severe-Lymphoid-NK\|Severe / Condition, Lineage, Cell class and cell subclass	IL12RB2 RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	1.56e-06	198	126	7	26b6d20527d22ce68067cdaea6b4330cb779f91b
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES SV2C GPR171 KLRC1	4.07e-06	148	126	6	3aa47398cb805c6c6e16b375cc3e9c7f04bb91f4
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1 PSD4	5.31e-06	155	126	6	93513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBR1 TBX21 EOMES LDB3 MTMR7 KLRC1	5.72e-06	157	126	6	a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1 PSD4	5.72e-06	157	126	6	ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB2 TBX21 FAAH SV2C KLRC1 PSD4	6.15e-06	159	126	6	4750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ToppCell	control-NK_CD56bright\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IL12RB2 TBX21 EOMES AGK PLA2G6 KLRC1	6.38e-06	160	126	6	f49c810072604c4dee51025073c9e088c00daf4a
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 FAAH SV2C KLRC1 PSD4	6.61e-06	161	126	6	8e787cc7f5e818cad1a6ed143a5fe310993e030b
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 FAAH SV2C KLRC1 PSD4	6.61e-06	161	126	6	ca9233370490e27b9a1892669d6b82db2136180e
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB2 TBX21 FAAH EOMES GPR171 KLRC1	6.85e-06	162	126	6	04ccd3d216f8f41afd3434a61264f03d6324db35
ToppCell	Severe-Lymphoid-NK-CD8_T\|Severe / Condition, Lineage, Cell class and cell subclass	IL12RB2 SYNE1 EOMES PLA2G6 GPR171 KLRC1	8.15e-06	167	126	6	8d41015871616ab7eced5104cd8f70d0efe504f2
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB SPI1 SCN8A LRRC8B ICA1L GOT1	8.43e-06	168	126	6	84977db9d71e59208727885320cc18d80d064380
ToppCell	facs-Lung-nan-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 BANK1 PSD4	9.64e-06	172	126	6	7af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCell	COVID-19_Moderate-NK_CD56bright\|COVID-19_Moderate / disease group, cell group and cell class	IL12RB2 TBX21 SIX3 EOMES AGK KLRC1	9.96e-06	173	126	6	a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 SIX3 FAAH EOMES GPR171 KLRC1	1.13e-05	177	126	6	31201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 SIX3 FAAH EOMES GPR171 KLRC1	1.13e-05	177	126	6	89d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCell	control-NK_CD56bright\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IL12RB2 TBX21 EOMES AGK PLA2G6 KLRC1	1.17e-05	178	126	6	f3d0bc9a39ed94785676f10c285c5b031bc93aae
ToppCell	facs-Heart-RA-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 SIX3 FAAH EOMES GPR171 KLRC1	1.25e-05	180	126	6	9be0af61d496a29d737bb772ad09864797994299
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 SYNE1 TBX21 EOMES AGK KLRC1	1.29e-05	181	126	6	9c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 PKHD1L1 LDB3 LOXHD1 TRPM3 USH2A	1.41e-05	184	126	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 PKHD1L1 LDB3 LOXHD1 TRPM3 USH2A	1.41e-05	184	126	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 PKHD1L1 LDB3 LOXHD1 TRPM3 USH2A	1.41e-05	184	126	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RPS4Y1 SYNE1 TBX21 EOMES TBR1 KLRC1	1.46e-05	185	126	6	097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MFAP3L TRPM3 SCN7A SV2C USH2A CUX1	1.46e-05	185	126	6	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 RPS4Y1 TBX21 EOMES AGK KLRC1	1.50e-05	186	126	6	5ad37549592eab23f166196ebf0cb9c8ddf26082
ToppCell	COVID-NK-\|COVID / Condition, Cell_class and T cell subcluster	SYNE1 TBX21 EOMES SERPINE1 TRPV3 KLRC1	1.60e-05	188	126	6	fabdd68a9734d35e75e1f4a4bfd5c531cfc099f1
ToppCell	COVID-NK\|COVID / Condition, Cell_class and T cell subcluster	SYNE1 TBX21 EOMES SERPINE1 TRPV3 KLRC1	1.60e-05	188	126	6	0beaa671611110a11e46156f54f5202cc24967a4
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	PKHD1L1 TRPM3 SERPINE1 PDE7B EPAS1 GULP1	1.65e-05	189	126	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 SYNE1 TBX21 EOMES AGK KLRC1	1.65e-05	189	126	6	3e148accffc6ab249fb0dff7f3bf5a7fff9da773
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR1 IL12RB2 MMS22L TRPM7 ZNF224 KIDINS220	1.75e-05	191	126	6	9454f642c3621370fa23640b631301346b300950
ToppCell	T/NK_cells-CD56bright_NK_cell\|World / Lineage and Cell class	IL12RB2 TBX21 EOMES AGK PLA2G6 KLRC1	1.80e-05	192	126	6	528b5b790a0e8966d04ffbc83b049c93bac17537
ToppCell	Leuk-UTI-Lymphocyte-T_NK\|Leuk-UTI / Disease, Lineage and Cell Type	RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	1.80e-05	192	126	6	b3e1c8a260782c2b79e3bda6557542055edde6fb
ToppCell	Mild_COVID-19-T/NK-NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	IL12RB2 TBX21 EOMES AGK PDE7B KLRC1	1.85e-05	193	126	6	9c455d9d845fa230e9a61d9a5f9d6a2ccf5d7350
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL12RB2 TBX21 EOMES AGK PLA2G6 KLRC1	1.91e-05	194	126	6	aee60da2e7aed161cdd4abbfad6864665aaa8f5c
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL12RB2 RPS4X TBX21 EOMES PDE7B KLRC1	1.96e-05	195	126	6	90c77b7f245b1bf80ba293583f8fe343b14c7f67
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL12RB2 RPS4X TBX21 EOMES PDE7B KLRC1	1.96e-05	195	126	6	4eb13aa9fc496caca6e0a4fb80d11a60cf2511b0
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL12RB2 RPS4X TBX21 EOMES PDE7B KLRC1	1.96e-05	195	126	6	89d832d1715f2720caa8cdd1e7ef847d79642556
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL12RB2 RPS4X RPS4Y1 TBX21 EOMES KLRC1	2.02e-05	196	126	6	64b23d819efddb25024c86f2e1b5dc4159337ddd
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL12RB2 RPS4X RPS4Y1 TBX21 EOMES KLRC1	2.02e-05	196	126	6	ba46f80d1497eaf4d71b59504106ba4b84e4ff9f
ToppCell	Control-Lymphocyte-T_NK-NK_CD56bright\|Control / Disease, Lineage and Cell Type	IL12RB2 TBX21 EOMES SERPINE1 AGK KLRC1	2.02e-05	196	126	6	c0ebef067aa333c7a18c697031b0417b3335b75c
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL12RB2 RPS4X RPS4Y1 TBX21 EOMES KLRC1	2.02e-05	196	126	6	eb0b711ca6da7b5e5313791c3c3985358e2a222e
ToppCell	Severe_COVID-19-T/NK-NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	IL12RB2 SYNE1 TBX21 EOMES GPR171 KLRC1	2.08e-05	197	126	6	cc20162892b59e48653981f91fc9a0c27064444d
ToppCell	ASK452-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	UBR1 RPS4X RPS4Y1 PKHD1L1 EIF3L SERPINE1	2.08e-05	197	126	6	e92757e988888347c74286cc42c262b03159b0b9
ToppCell	ICU-NoSEP-Lymphocyte-T_NK\|ICU-NoSEP / Disease, Lineage and Cell Type	RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	2.08e-05	197	126	6	951bb4c1e6f5c5fd7e7d58b36eb3f31e9201fb66
ToppCell	Sepsis-URO-Lymphocyte-T/NK-gd_T\|URO / Disease, condition lineage and cell class	TBX21 EOMES NTN4 SCN8A GPR171 KLRC1	2.14e-05	198	126	6	cb584f7754ef4e6d9ec7155022852f2d2676ab4f
ToppCell	control-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RPS4X RPS4Y1 TBX21 EOMES GPR171 KLRC1	2.14e-05	198	126	6	14bd612e9f9358ebff6cf8dda6a3165de9e4e3b0
ToppCell	control-Lymphocytic-NK_cells\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RPS4X SYNE1 TBX21 EOMES UHMK1 KLRC1	2.14e-05	198	126	6	1c779101d0c5f29de5cc7170d784931d6e34bdcd
ToppCell	MS-IIF-Lymphocyte-T/NK-gd_T\|IIF / Disease, condition lineage and cell class	IL12RB2 TBX21 EOMES CHD5 GPR171 KLRC1	2.20e-05	199	126	6	2c0e981839c256d76fa049532c8d49f31ce9bfee
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	RPS4Y1 KIDINS220 TRPM3 CHD5 EIF3L SLITRK5	2.20e-05	199	126	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	RPS4Y1 KIDINS220 TRPM3 CHD5 EIF3L SLITRK5	2.20e-05	199	126	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	COVID-19_Severe-CD8+_T_activated\|COVID-19_Severe / disease group, cell group and cell class	RPS4Y1 SYNE1 TBX21 EOMES NTN4 KLRC1	2.20e-05	199	126	6	a16b961996291bd5958c3851b7fdd7b45c53e19b
ToppCell	Severe-Lymphoid\|Severe / Condition, Lineage, Cell class and cell subclass	IL12RB2 RPS4X SYNE1 TBX21 GPR171 KLRC1	2.20e-05	199	126	6	928e346b0f31d991ebab12fefb4eb9f4249e601d
ToppCell	distal-Hematologic-CD8+_Memory/Effector_T-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RPS4X RPS4Y1 TBX21 EOMES GPR171 KLRC1	2.20e-05	199	126	6	a2f54e56013ec2c83407fdb3fcbe5d10d146cca4
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK\|Leuk-UTI / Disease, condition lineage and cell class	RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	2.26e-05	200	126	6	88eba6199fb1edd745ab09216df3d43b27f84c6c
ToppCell	Control-Control-Lymphocyte-T/NK-NK_CD56bright\|Control / Disease, condition lineage and cell class	IL12RB2 TBX21 EOMES AGK PLA2G6 KLRC1	2.26e-05	200	126	6	d843fe0781c7699afead4429c526441c6fdb8cba
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-gd_T\|Int-URO / Disease, condition lineage and cell class	SYNE1 TBX21 EOMES TRPV3 GPR171 KLRC1	2.26e-05	200	126	6	d382ee690e370886009eff42d14952d44a6d4d18
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK\|ICU-NoSEP / Disease, condition lineage and cell class	RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	2.26e-05	200	126	6	31c06b73292015e69038e52ae67322f458f37c71
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK\|Bac-SEP / Disease, condition lineage and cell class	RPS4X RPS4Y1 SYNE1 TBX21 GPR171 KLRC1	2.26e-05	200	126	6	b8087202a626e64a49292c0a5f7f7376b7b14a9c
ToppCell	Sepsis-URO-Lymphocyte-T/NK\|URO / Disease, condition lineage and cell class	RPS4X SYNE1 TBX21 EOMES GPR171 KLRC1	2.26e-05	200	126	6	ef40ed94261bdb79b7bde4196ff08bf327717b6b
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IL12RB2 SYNE1 TBX21 EOMES KLRC1 PSD4	2.26e-05	200	126	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_Tem\|Leuk-UTI / Disease, condition lineage and cell class	IL12RB2 RPS4X SYNE1 EOMES NTN4 GPR171	2.26e-05	200	126	6	65ea3ba16c75f8e9a5aee3ba0c7ab11a961fff7c
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-NK_CD56bright\|Int-URO / Disease, condition lineage and cell class	IL12RB2 EOMES SERPINE1 AGK PLA2G6 KLRC1	2.26e-05	200	126	6	776b6590e21dbd80b6679433727070e06bf01f0f
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-NK_CD56bright\|Multiple_Sclerosis / Disease, condition lineage and cell class	IL12RB2 EOMES AGK PLA2G6 KLRC1 EPAS1	2.26e-05	200	126	6	d06bea5b4af9559a517e769a373b873cd7bdcb48
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)\|Striatum / BrainAtlas - Mouse McCarroll V32	OPN1MW TAS2R42 UHMK1 GPR171	2.37e-05	59	126	4	a72de8cda377c87fa9a6fbda72735d850650f9f4
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	OPN1MW TAS2R42 UHMK1 GPR171	2.37e-05	59	126	4	3ab024fa7a927177da0dc764cee46dabdd008040
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	5.42e-05	143	126	5	138033ff447a61a1bc289b21db82151dcc6a4c7e
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	6.38e-05	148	126	5	7cb4865a1e9522e24f9c14799568b67172bd99dc
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	6.80e-05	150	126	5	c18d3f66b384ec9ee0b8fb6a369b9a524b5dcaeb
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB2 TBX21 EOMES GPR171 KLRC1	6.80e-05	150	126	5	1f83e3be3f94aefe991a3ccd292c2d11ddef858e
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB2 TBX21 EOMES GPR171 KLRC1	6.80e-05	150	126	5	cd666db614bc1b43d71e8eb7bf38cae4d580be80
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB2 TBX21 EOMES GPR171 KLRC1	6.80e-05	150	126	5	f6ed3e7b36014d1e429b255b0027d89865e1ac07
ToppCell	facs-GAT-Fat-3m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.02e-05	151	126	5	3d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.02e-05	151	126	5	1525422afadff68a1525ced6d5db45fdea450678
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.24e-05	152	126	5	ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.47e-05	153	126	5	2a94092937267cd2282452dfde3d328d763d4294
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.47e-05	153	126	5	ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.47e-05	153	126	5	e25ddf75d78edfac962c8ec503c9f70f0f7f25bc
ToppCell	facs-MAT-Fat-3m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.70e-05	154	126	5	391d40ef902773ffe832a50a14d35d31c56d3723
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 DET1 TBX21 EOMES KLRC1	7.70e-05	154	126	5	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX21 EOMES GPR171 KLRC1 BANK1	7.94e-05	155	126	5	efe69145910c5e049d0ed30699c26ef963e0a285
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	7.94e-05	155	126	5	d8e9f355ce933f6383c3d1e35ff55235a95c7fcd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANKK1 TOPAZ1 EPB41L5 B3GALT5 GULP1	7.94e-05	155	126	5	90e629681a72baacc7981b82883866a487638dbc
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	ZNF195 ZNF224 TRRAP SMG9 PSD4	7.94e-05	155	126	5	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	facs-BAT-Fat-24m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES METTL13 ASCC2	7.94e-05	155	126	5	550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCell	facs-MAT-Fat-18m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	8.44e-05	157	126	5	e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 TBX21 EOMES GPR171 KLRC1	8.69e-05	158	126	5	5d926be5a0ebe8257cd552afa7844171f9ff01c0
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 TBX21 EOMES GPR171 KLRC1	8.69e-05	158	126	5	8844fba9c1e41f062edf3110d025f33b86afb951
Drug	Azathymine, 6 [932-53-6]; Up 200; 31.4uM; MCF7; HT_HG-U133A	RPS4Y1 SIX3 LDB3 WNT16 SERPINE1 SCN8A SUGP1 BANK1 DOP1A	1.60e-06	196	127	9	4106_UP
Disease	blue cone monochromacy (implicated_via_orthology)	OPN1LW OPN1MW OPN1MW2 OPN1MW3	2.69e-10	4	121	4	DOID:0050679 (implicated_via_orthology)
Disease	docosahexaenoic acid measurement	CPT1A JMJD1C SUGP1 UGT2B15 UGT2B17 CUX1	1.45e-05	127	121	6	EFO_0007761
Disease	Cone monochromatism	OPN1LW OPN1MW	1.67e-05	2	121	2	cv:C0339537
Disease	BORNHOLM EYE DISEASE	OPN1LW OPN1MW	1.67e-05	2	121	2	C3159311
Disease	Achromatopsia incomplete, X-linked	OPN1LW OPN1MW	1.67e-05	2	121	2	C2931753
Disease	Red-green dyschromatopsia	OPN1LW OPN1MW	1.67e-05	2	121	2	cv:C0155016
Disease	Cone monochromatism	OPN1LW OPN1MW	1.67e-05	2	121	2	C0339537
Disease	BLUE CONE MONOCHROMACY	OPN1LW OPN1MW	1.67e-05	2	121	2	303700
Disease	blue cone monochromacy (is_implicated_in)	OPN1LW OPN1MW	1.67e-05	2	121	2	DOID:0050679 (is_implicated_in)
Disease	cholic acid glucuronide measurement	UGT2B15 UGT2B17	4.99e-05	3	121	2	EFO_0800574
Disease	inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 measurement	NLRP12 JMJD1C	4.99e-05	3	121	2	EFO_0801697
Disease	X-25937 measurement	UGT2B15 UGT2B17	9.95e-05	4	121	2	EFO_0800937
Disease	amyloidosis (is_implicated_in)	SERPINE1 GOT1	9.95e-05	4	121	2	DOID:9120 (is_implicated_in)
Disease	omega-3 polyunsaturated fatty acid measurement	CPT1A JMJD1C SUGP1 UGT2B15 UGT2B17	1.29e-04	118	121	5	EFO_0010119
Disease	Cerebellar Ataxia	SYNE1 SCN8A	1.65e-04	5	121	2	C0007758
Disease	gamma-enolase measurement	NLRP12 JMJD1C	2.47e-04	6	121	2	EFO_0021845
Disease	riboflavin kinase measurement	PRUNE2 NLRP12	2.47e-04	6	121	2	EFO_0802016
Disease	platelet component distribution width	PRUNE2 SYNE1 JMJD1C METTL13 DLC1 TRPM3 BTBD7 SUGP1 PLA2G6 EPAS1 CUX1	2.85e-04	755	121	11	EFO_0007984
Disease	X-24574 measurement	UGT2B15 UGT2B17	3.46e-04	7	121	2	EFO_0800897
Disease	rho GTPase-activating protein 30 measurement	CYP4V2 NLRP12	3.46e-04	7	121	2	EFO_0802012
Disease	MASA syndrome (implicated_via_orthology)	TRPM7 TRPM3	3.46e-04	7	121	2	DOID:0060246 (implicated_via_orthology)
Disease	deoxycholic acid glucuronide measurement	UGT2B15 UGT2B17	4.59e-04	8	121	2	EFO_0800575
Disease	breast cancer anti-estrogen resistance protein 3 measurement	NLRP12 JMJD1C	4.59e-04	8	121	2	EFO_0008040
Disease	40S ribosomal protein S4, X isoform measurement	NLRP12 JMJD1C	4.59e-04	8	121	2	EFO_0801334
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	CPT1A JMJD1C SUGP1 UGT2B15 UGT2B17 PLA2G6	5.12e-04	243	121	6	EFO_0004612, EFO_0020944
Disease	urticaria, response to non-steroidal anti-inflammatory, angioedema	BANK1 EPAS1	5.89e-04	9	121	2	EFO_0005531, EFO_0005532, EFO_0005533
Disease	Adenocarcinoma of large intestine	RIPK1 TRRAP DLC1 CUX1	6.68e-04	96	121	4	C1319315
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN7A SCN8A	7.35e-04	10	121	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN7A SCN8A	7.35e-04	10	121	2	DOID:0080422 (implicated_via_orthology)
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	UGT2B15 UGT2B17	7.35e-04	10	121	2	EFO_0022090
Disease	C-X-C motif chemokine 5 measurement	NLRP12 JMJD1C	7.35e-04	10	121	2	EFO_0008058
Disease	Autistic Disorder	CHD4 TRRAP JMJD1C SCN7A SERPINE1 TBR1	7.44e-04	261	121	6	C0004352
Disease	DNA repair protein RAD51 homolog 4 measurement	UGT2B15 UGT2B17	8.95e-04	11	121	2	EFO_0801531
Disease	free androgen index	JMJD1C UGT2B15 UGT2B17 GREB1 QSOX2 EPAS1 CUX1	9.11e-04	374	121	7	EFO_0007005
Disease	Kidney Failure, Chronic	CYBB CPT1A SERPINE1	1.02e-03	48	121	3	C0022661
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN7A SCN8A	1.07e-03	12	121	2	DOID:0060170 (implicated_via_orthology)
Disease	renal fibrosis (biomarker_via_orthology)	CYBB SERPINE1	1.07e-03	12	121	2	DOID:0050855 (biomarker_via_orthology)
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	UGT2B15 UGT2B17	1.07e-03	12	121	2	EFO_0800291
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	CPT1A UGT2B15 BANK1	1.08e-03	49	121	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	JMJD1C UGT2B15 UGT2B17	1.15e-03	50	121	3	EFO_0010732
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	UGT2B15 UGT2B17	1.26e-03	13	121	2	EFO_0800293
Disease	X-19141 measurement	UGT2B15 UGT2B17	1.26e-03	13	121	2	EFO_0800799
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	CPT1A JMJD1C SUGP1 PLA2G6 BANK1	1.43e-03	200	121	5	EFO_0004611, EFO_0020945
Disease	C-X-C motif chemokine 11 measurement	JMJD1C CUX1	1.47e-03	14	121	2	EFO_0008057
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	UGT2B15 UGT2B17	1.47e-03	14	121	2	EFO_0800283
Disease	colorectal cancer (is_implicated_in)	BRIP1 CHD4 DLC1 TRPV3	1.58e-03	121	121	4	DOID:9256 (is_implicated_in)
Disease	Tremor, Rubral	SOX2 SCN8A	1.93e-03	16	121	2	C0750940
Disease	Ataxia, Appendicular	SOX2 SCN8A	1.93e-03	16	121	2	C0750937
Disease	Ataxia, Motor	SOX2 SCN8A	1.93e-03	16	121	2	C0278161
Disease	Ataxia, Sensory	SOX2 SCN8A	1.93e-03	16	121	2	C0240991
Disease	Abnormal coordination	SOX2 SCN8A	1.93e-03	16	121	2	C0520966
Disease	Ataxia, Truncal	SOX2 SCN8A	1.93e-03	16	121	2	C0427190
Disease	muscular dystrophy (is_implicated_in)	SYNE1 POMGNT1	2.18e-03	17	121	2	DOID:9884 (is_implicated_in)
Disease	alcoholic liver cirrhosis	SUGP1 PDE7B	2.18e-03	17	121	2	EFO_1000802
Disease	glucuronate measurement	EPB41L5 MTMR7	2.44e-03	18	121	2	EFO_0010486
Disease	5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement	UGT2B15 UGT2B17	2.44e-03	18	121	2	EFO_0800288
Disease	squamous cell carcinoma (is_marker_for)	SOX2 RIPK1	2.72e-03	19	121	2	DOID:1749 (is_marker_for)
Disease	etiocholanolone glucuronide measurement	UGT2B15 UGT2B17	2.72e-03	19	121	2	EFO_0800362
Disease	hemifacial microsomia	ANO1 EPAS1	2.72e-03	19	121	2	MONDO_0015398
Disease	triglycerides to phosphoglycerides ratio	JMJD1C SUGP1 BANK1	2.78e-03	68	121	3	EFO_0022327
Disease	diverticular disease	MMS22L TBX21 ANO1 DLC1 ICA1L	2.94e-03	236	121	5	EFO_0009959
Disease	maximal midexpiratory flow rate	BRIP1 TUBGCP6	3.02e-03	20	121	2	EFO_0004313
Disease	urticaria	ITPKB ZNF728	3.02e-03	20	121	2	EFO_0005531
Disease	androsterone glucuronide measurement	UGT2B15 UGT2B17	3.02e-03	20	121	2	EFO_0800317
Disease	neurodegenerative disease (implicated_via_orthology)	UBR1 CDNF PLA2G6 SDHA	3.05e-03	145	121	4	DOID:1289 (implicated_via_orthology)
Disease	Infiltrating duct carcinoma of female breast	ANKK1 TRPM7	3.33e-03	21	121	2	C3165106
Disease	Anophthalmia-microphthalmia syndrome	SOX2 SIX3	3.33e-03	21	121	2	cv:C5680330
Disease	docosahexaenoic acid to total fatty acids percentage	CPT1A JMJD1C	3.33e-03	21	121	2	EFO_0022262
Disease	blood pressure	SYNE1 BANK1	3.65e-03	22	121	2	EFO_0004325
Disease	X-24947 measurement	UGT2B15 UGT2B17	3.65e-03	22	121	2	EFO_0800910
Disease	Ovarian Serous Adenocarcinoma	TRPM7 TRRAP	3.99e-03	23	121	2	C1335177
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	EPAS1 SDHA	3.99e-03	23	121	2	C1708353
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	CPT1A JMJD1C SUGP1	4.09e-03	78	121	3	EFO_0022187

Protein segments in the cluster

Peptide	Gene	Start	Entry
FKHWQMGKSGLEMIQ	BANK1	701	Q8NDB2
HWMRQEISFGKLKLT	EOMES	361	O95936
STSHLMWKRMKNLRG	EPAS1	731	Q99814
MTVFFKTLRNHWKKT	AGK	1	Q53H12
KMRVAELKQILHSWG	CDNF	141	Q49AH0
WMMIHRILNHSFDKK	CHD5	591	Q8TDI0
QFMELRRMEHLVKFW	AKAP10	141	O43572
WNKLTVRGKEPFHKM	CUX1	596	P39880
NMHVKISDFGLSKWM	ANKK1	156	Q8NFD2
GDLWQRLSHSRKKLM	ASCC2	306	Q9H1I8
MFTEHGKMSRATKIW	CPT1A	136	P50416
RKMTEKARVSHLMGW	BRWD3	1786	Q6RI45
LTLKTMMGIEWVHRF	B3GALT5	131	Q9Y2C3
IFSAQKWHSEKMAGK	DOP1A	1536	Q5JWR5
FDMIKDQFLKSWHRL	TENT2	451	Q6PIY7
KQFHTGVEIKMWAIA	AGO3	441	Q9H9G7
MWKMQLLDENHLFIK	DET1	331	Q7L5Y6
EIAEMSLKGHRKAWN	CCDC113	346	Q9H0I3
SLKGHRKAWNRMKIT	CCDC113	351	Q9H0I3
WVTMNGLAFKHEIKD	KLRC1	186	P26715
TQRLMMWKKRGGVHT	RAD21L1	331	Q9H4I0
AATMKFKKLRHPLNW	OPN1LW	76	P04000
AATMKFKKLRHPLNW	OPN1MW3	76	P0DN78
KMRISGIFLTNHIKW	QSOX2	401	Q6ZRP7
LVEHVGMKNLKSWAS	PUM3	581	Q15397
RDTGQIFAMKMLHKW	CDC42BPG	91	Q6DT37
AATMKFKKLRHPLNW	OPN1MW2	76	P0DN77
FRGLMKLKHLDLSWN	LRRC9	756	Q6ZRR7
WVSNKKHGMGRLTFK	RSPH10B	311	P0C881
WVSNKKHGMGRLTFK	RSPH10B2	311	B2RC85
KKEMNMNFGDWHLFR	KIDINS220	1256	Q9ULH0
KWQMHDSGLLNITKV	MFAP3L	101	O75121
KIMGEVMHALRQTWH	LDB3	616	O75112
VTVGKHFVKQLRMWQ	GREB1	991	Q4ZG55
FMVLIEKDWISFGHK	MTMR7	366	Q9Y216
RRKFMLQWESHTFGK	NLRP11	101	P59045
LVFKHKMKNLVWTSG	EIF3L	491	Q9Y262
QRALIWKGHMAFLLM	MMS22L	566	Q6ZRQ5
IMSMVWKRLNDHGKN	EPN2	56	O95208
LMNHTKGKIMVVWTR	CFAP65	676	Q6ZU64
GLIKTSFSRMLWMDK	DHRS4L1	216	P0CG22
GVHKKMNISLWKAES	JMJD1C	2196	Q15652
KWTAILGLHMKSNLT	TMPRSS15	836	P98073
LWNMVNVTKAKGRHD	IL12RB2	266	Q99665
GWHLERMTLMNTLNK	LOXHD1	501	Q8IVV2
MSHKLLKGFAILSWI	OR4L1	136	Q8NH43
RHMLSKVGMWDFDIF	PDE7B	106	Q9NP56
MEFKKEFGRNWHLLT	GPR171	166	O14626
DMIHFWKRLSRLMSK	NSMF	436	Q6X4W1
LMMWALKDVCFHLKR	TUBGCP6	1636	Q96RT7
ATFMEHWKRKQMRLN	ANO1	421	Q5XXA6
FTEMGKIPRWVFHLK	LRRC8B	496	Q6P9F7
AATMKFKKLRHPLNW	OPN1MW	76	P04001
LAVKFHTMITEKWGL	THAP12	306	O43422
KIWSGNEMLLTLHKM	BRIP1	466	Q9BX63
MATNFLVGEKIWFHK	EEF1DP3	1	Q658K8
KTTALKQLQGHMWRA	ENOPH1	106	Q9UHY7
LNKAKWLEMYGVDMH	EPB41L5	221	Q9HCM4
MNRAFSRKKDKTWMH	GULP1	1	Q9UBP9
WKQIASVMKHRFLFP	GOT1	206	P17174
HLTGWLMTLKKTFVL	ANKH	386	Q9HCJ1
LMFKEGWEHKKSLQI	CYP4V2	246	Q6ZWL3
YLIKWGEHQLMKRIA	BTBD7	466	Q9P203
RNLTFHKMVAWMIAL	CYBB	96	P04839
IMSMIWKRLNDHGKN	EPN1	56	Q9Y6I3
MKSRSAGKLWELQHE	FAAH	436	O00519
LHMTFWGKEENRKAV	HLTF	146	Q14527
ILKKAVGHFSREGWM	METTL13	166	Q8N6R0
LLGFWKKTARMMSQI	ICA1L	231	Q8NDH6
WMMIHRILNHSVDKK	CHD4	621	Q14839
MVFDMEGLSLKHLWK	SEC14L4	151	Q9UDX3
MNKGVFMKLIIFSWA	OR10A6	136	Q8NH74
MLLNLHKKSWMEGLT	PSMD14	216	O00487
DWVKTHTKGMISNLL	SERPINE1	161	P05121
MKSMQGWRKSSINLF	RXFP3	106	Q9NSD7
AMFLLLIFSMWKHRK	TAS2R14	196	Q9NYV8
LGKTVIMLWHMTNHL	TAS2R42	81	Q7RTR8
LLDVKSRMMLVTWQH	USH2A	2541	O75445
MHNSEISKRLGAEWK	SOX2	66	P48431
AWMILKLIHDTNMRA	SV2C	356	Q496J9
GAHWMRQEISFGKLK	TBR1	296	Q16650
HRLRGSILFKWMTME	PRUNE2	166	Q8WUY3
MEMVKTKWDHFGSNF	SYNE1	1441	Q8NF91
LKHLKTFDRGMVWNT	SDHA	546	P31040
SFVQHWKPSLGRKVM	NTN4	606	Q9HB63
IKNMVHWSPFVMSFK	ITPKB	651	P27987
LWRLFRKKNHFLMVG	POMGNT1	611	Q8WZA1
RGWKMFHTLLRGMVL	PSD4	801	Q8NDX1
RMKHSIKLVDDQMNW	SMG9	176	Q9H0W8
WKHSRTMMLVVFKSA	STRIP1	681	Q5VSL9
KFTKESHGKLQAMWL	SIX3	156	O95343
KHWMLDKLTGVFAPR	RPS4Y1	16	P22090
KHWMLDKLTGVFAPR	RPS4Y2	16	Q8TD47
KHWMLDKLTGVFAPR	RPS4X	16	P62701
LHWAKNAEMARMLLK	PLA2G6	291	O60733
HRWGIQKGNRKKMTY	SPI1	211	P17947
MHNSEISKRLGAEWK	SOX1	76	O00570
HIKIADLGLASFKMW	RIPK1	151	Q13546
KHGFSWAVPKFMKRI	DLC1	1051	Q96QB1
EKKNIMSSRHWGPIF	STON2	436	Q8WXE9
KWKAMHNRLYGMNEE	CTSL	31	P07711
HKRAMQDMQLLWEKA	SUGP1	461	Q8IWZ8
WAEQLTKMGRGKHFI	SUGP1	511	Q8IWZ8
WKVMSILKGRKFQQH	TAS2R7	301	Q9NYW3
NMDLRTVKHFIWKSG	WDR48	651	Q8TAF3
GFMRATVKFWHKILK	RINT1	211	Q6NUQ1
RKMHSWMLQTLAFAV	SLITRK5	16	O94991
FHELMVWAVLMKRQK	TRPM3	661	Q9HCF6
MKRQKMALFFWQHGE	TRPM3	671	Q9HCF6
EELRKKQKMGGFHWM	TCEAL6	151	Q6IPX3
GKAFKWSSNLMEHKR	ZNF728	486	P0DKX0
QKFALRLGSWMNKIM	UBR1	311	Q8IWV7
GIAIMKHFGWKADLR	THUMPD2	231	Q9BTF0
KGVAWTKLKVHAFMQ	SCN8A	1006	Q9UQD0
WKTMSSFEKIGHLLK	WNT16	236	Q9UBV4
QKKRLTHMSGWMALI	PKHD1L1	2876	Q86WI1
EELRKKQKMGGFHWM	TCEAL3	151	Q969E4
TLKERVQWRGEMKHF	ZMYM2	776	Q9UBW7
GTVFRHWKKNPLTME	ZMYM2	1241	Q9UBW7
WMNDFRFLGKHSVLK	TOPAZ1	1051	Q8N9V7
IWQMRHLKSFFEAKK	TMED4	211	Q7Z7H5
THKMGWLQLLGRMFV	TRPV3	476	Q8NET8
MGLFMGNLKHKCFRW	SCN7A	256	Q01118
LRLKMFREDHGSWMT	TMEM117	96	Q9H0C3
AVFWIEFVMRHKGAK	UGT2B15	461	P54855
TFHFLREEKIWMMKT	ZNF224	56	Q9NZL3
FQSKMEKWHEETGLK	UHRF1BP1	401	Q6BDS2
DPQWSRMFMSFLKHK	TRRAP	1581	Q9Y4A5
FSGMKLKHTVRSQEW	UHMK1	236	Q8TAS1
HWMRQEVSFGKLKLT	TBX21	231	Q9UL17
LMKRQVMARFLWQHG	TRPM7	631	Q96QT4
GRVFMWFSDITKHKK	ZNF195	556	O14628
AVFWIEFVMRHKGAK	UGT2B17	461	O75795
IGKSMLAHKVMLDWA	NLRP12	221	P59046
LAHKVMLDWADGKLF	NLRP12	226	P59046
VLWLFGMDLNKMTHS	NLRP12	1031	P59046