Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA photolyase activity

CRY2 CRY1

4.53e-062432GO:0003913
GeneOntologyMolecularFunctionDNA (6-4) photolyase activity

CRY2 CRY1

4.53e-062432GO:0003914
GeneOntologyMolecularFunctiondeoxyribodipyrimidine photo-lyase activity

CRY2 CRY1

4.53e-062432GO:0003904
GeneOntologyMolecularFunctionblue light photoreceptor activity

CRY2 CRY1

4.53e-062432GO:0009882
GeneOntologyMolecularFunctionhexose-phosphate:phosphate antiporter activity

SLC37A2 SLC37A3

2.71e-054432GO:0015526
GeneOntologyMolecularFunctionhexose phosphate transmembrane transporter activity

SLC37A2 SLC37A3

2.71e-054432GO:0015119
GeneOntologyMolecularFunctionglucose-6-phosphate transmembrane transporter activity

SLC37A2 SLC37A3

2.71e-054432GO:0015152
GeneOntologyMolecularFunctionglucose 6-phosphate:phosphate antiporter activity

SLC37A2 SLC37A3

2.71e-054432GO:0061513
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 SLC5A4

3.88e-05296436GO:0015291
GeneOntologyMolecularFunctionorganophosphate:phosphate antiporter activity

SLC37A2 SLC37A3

9.45e-057432GO:0015315
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A11 SLC5A4

9.45e-057432GO:0005412
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A11 SLC6A8 SLC15A1 SLC5A4

1.24e-04119434GO:0015294
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 TMEM38B ITPR1 SLC5A4

1.85e-04758438GO:0015318
GeneOntologyMolecularFunctionsymporter activity

SLC5A11 SLC6A8 SLC15A1 SLC5A4

3.01e-04150434GO:0015293
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 SLC5A4

5.19e-04477436GO:0022804
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A11 SLC5A4

6.04e-0417432GO:0005402
GeneOntologyMolecularFunctionphotoreceptor activity

CRY2 CRY1

6.04e-0417432GO:0009881
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A11 SLC6A8 SLC5A4

7.06e-0481433GO:0015370
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC37A2 SLC37A3

1.21e-0324432GO:0005315
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC5A11 SLC5A4

1.32e-0325432GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC5A11 SLC5A4

1.32e-0325432GO:0015149
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC5A11 SLC5A4

1.54e-0327432GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC5A11 SLC5A4

1.77e-0329432GO:0051119
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC5A11 SLC6A8 SLC15A1 TMEM38B ITPR1 SLC5A4

2.12e-03627436GO:0022890
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC37A2 SLC37A3

2.16e-0332432GO:0005452
GeneOntologyMolecularFunctionphosphatase binding

CRY2 FCRL3 ITPR1 CRY1

2.46e-03264434GO:0019902
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC5A11 SLC6A8 SLC15A1 TMEM38B ITPR1 SLC5A4

2.83e-03664436GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC5A11 SLC6A8 TMEM38B ITPR1 SLC5A4

3.11e-03465435GO:0046873
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC37A2 SLC37A3

3.19e-0339432GO:0015605
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 TMEM38B ITPR1 SLC5A4

3.31e-031180438GO:0022857
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC5A11 SLC5A4

3.69e-0342432GO:0015144
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC5A11 SLC6A8 SLC15A1 SLC5A4

3.93e-03301434GO:0022853
GeneOntologyMolecularFunctionFAD binding

CRY2 CRY1

4.05e-0344432GO:0071949
GeneOntologyMolecularFunctionchannel inhibitor activity

SLC15A1 ITPR1

5.20e-0350432GO:0016248
GeneOntologyMolecularFunctiontransporter inhibitor activity

SLC15A1 ITPR1

5.40e-0351432GO:0141110
GeneOntologyMolecularFunctiontransporter activity

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 TMEM38B ITPR1 SLC5A4

5.64e-031289438GO:0005215
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A8 SLC37A2 SLC37A3

5.92e-03171433GO:0015103
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A11 SLC6A8 SLC5A4

5.92e-03171433GO:0015081
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

CRY2 CRY1

6.48e-0356432GO:0016830
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC5A11 SLC6A8 SLC15A1 TMEM38B ITPR1 SLC5A4

6.70e-03793436GO:0015075
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC37A2 SLC37A3

7.17e-0359432GO:1901505
GeneOntologyMolecularFunctionnuclear receptor binding

CRY2 FUS CRY1

7.58e-03187433GO:0016922
GeneOntologyMolecularFunctionmolecular function inhibitor activity

ADGRV1 SPINT2 SLC15A1 RECK ITPR1

8.80e-03596435GO:0140678
GeneOntologyMolecularFunctioncoreceptor activity

ZP2 RECK

1.05e-0272432GO:0015026
GeneOntologyMolecularFunctionglutamate receptor binding

PTPN4 FUS

1.32e-0281432GO:0035254
GeneOntologyBiologicalProcesscellular response to blue light

CRY2 CRY1

4.25e-062432GO:0071483
GeneOntologyBiologicalProcessblue light signaling pathway

CRY2 CRY1

4.25e-062432GO:0009785
GeneOntologyBiologicalProcessphosphate ion transport

CRY2 SLC37A2 SLC37A3

3.64e-0531433GO:0006817
GeneOntologyBiologicalProcessnegative regulation of corticosteroid hormone secretion

CRY2 CRY1

4.23e-055432GO:2000847
GeneOntologyBiologicalProcessnegative regulation of steroid hormone secretion

CRY2 CRY1

4.23e-055432GO:2000832
GeneOntologyBiologicalProcessnegative regulation of glucocorticoid secretion

CRY2 CRY1

4.23e-055432GO:2000850
GeneOntologyBiologicalProcessresponse to blue light

CRY2 CRY1

6.33e-056432GO:0009637
GeneOntologyBiologicalProcessnegative regulation of glucocorticoid receptor signaling pathway

CRY2 CRY1

6.33e-056432GO:2000323
GeneOntologyBiologicalProcesshexose phosphate transport

SLC37A2 SLC37A3

8.86e-057432GO:0015712
GeneOntologyBiologicalProcessglucose-6-phosphate transport

SLC37A2 SLC37A3

8.86e-057432GO:0015760
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

CRY2 GCGR NCOA4 PRCP CRY1

1.48e-04244435GO:0009755
GeneOntologyBiologicalProcessregulation of glucocorticoid receptor signaling pathway

CRY2 CRY1

2.77e-0412432GO:2000322
GeneOntologyBiologicalProcessregulation of glucocorticoid secretion

CRY2 CRY1

3.80e-0414432GO:2000849
GeneOntologyBiologicalProcessphosphate ion transmembrane transport

SLC37A2 SLC37A3

4.38e-0415432GO:0035435
GeneOntologyBiologicalProcessnegative regulation of circadian rhythm

CRY2 CRY1

5.00e-0416432GO:0042754
GeneOntologyBiologicalProcessglucocorticoid secretion

CRY2 CRY1

5.00e-0416432GO:0035933
GeneOntologyBiologicalProcessnuclear receptor-mediated glucocorticoid signaling pathway

CRY2 CRY1

5.66e-0417432GO:0042921
GeneOntologyBiologicalProcesscarbohydrate transport

SLC5A11 SLC37A2 SLC37A3 SLC5A4

6.00e-04186434GO:0008643
GeneOntologyBiologicalProcessnuclear receptor-mediated corticosteroid signaling pathway

CRY2 CRY1

6.36e-0418432GO:0031958
GeneOntologyBiologicalProcessregulation of protein kinase C signaling

MYADM ADGRV1

7.88e-0420432GO:0090036
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

CRY2 NCOA4 PRCP CRY1

8.17e-04202434GO:0141193
GeneOntologyBiologicalProcessregulation of corticosteroid hormone secretion

CRY2 CRY1

8.69e-0421432GO:2000846
DomainDNA_photolyase

CRY2 CRY1

4.94e-062422PF00875
DomainFAD_binding_7

CRY2 CRY1

4.94e-062422PF03441
DomainCryptochr/Photolyase_FAD-bd

CRY2 CRY1

4.94e-062422IPR005101
DomainPHR_CRY_ALPHA_BETA

CRY2 CRY1

4.94e-062422PS51645
DomainDNA_photolyase_N

CRY2 CRY1

4.94e-062422IPR006050
DomainSugar_P_transporter

SLC37A2 SLC37A3

2.95e-054422IPR000849
DomainEGF_LAM_2

ATRN LAMC3 ATRNL1

4.12e-0530423PS50027
DomainEGF_LAM_1

ATRN LAMC3 ATRNL1

4.12e-0530423PS01248
DomainEGF_Lam

ATRN LAMC3 ATRNL1

6.58e-0535423SM00180
DomainLaminin_EGF

ATRN LAMC3 ATRNL1

8.44e-0538423IPR002049
DomainCTDL_fold

ATRN COL4A5 ATRNL1 CD209

9.64e-05107424IPR016187
DomainG_PROTEIN_RECEP_F2_1

ADGRG5 GCGR ADGRV1

9.86e-0540423PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRG5 GCGR ADGRV1

9.86e-0540423PS50227
DomainGPCR_2_extracellular_dom

ADGRG5 GCGR ADGRV1

9.86e-0540423IPR001879
DomainG_PROTEIN_RECEP_F2_2

ADGRG5 GCGR ADGRV1

1.93e-0450423PS00650
Domain7tm_2

ADGRG5 GCGR ADGRV1

1.93e-0450423PF00002
DomainNA_SOLUT_SYMP_1

SLC5A11 SLC5A4

2.68e-0411422PS00456
DomainNA_SOLUT_SYMP_2

SLC5A11 SLC5A4

3.21e-0412422PS00457
DomainSSF

SLC5A11 SLC5A4

3.21e-0412422PF00474
DomainNa/solute_symporter

SLC5A11 SLC5A4

3.21e-0412422IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A11 SLC5A4

3.21e-0412422PS50283
DomainGPCR_2-like

ADGRG5 GCGR ADGRV1

3.31e-0460423IPR017981
DomainGPCR_2_secretin-like

ADGRG5 GCGR ADGRV1

3.31e-0460423IPR000832
DomainG_PROTEIN_RECEP_F2_4

ADGRG5 GCGR ADGRV1

3.48e-0461423PS50261
DomainC_TYPE_LECTIN_1

ATRN ATRNL1 CD209

7.70e-0480423PS00615
DomainLectin_C

ATRN ATRNL1 CD209

8.88e-0484423PF00059
DomainCLECT

ATRN ATRNL1 CD209

8.88e-0484423SM00034
DomainC_TYPE_LECTIN_2

ATRN ATRNL1 CD209

9.19e-0485423PS50041
DomainC-type_lectin-like

ATRN ATRNL1 CD209

9.50e-0486423IPR001304
Domain-

ATRN ATRNL1 CD209

1.35e-03974233.10.100.10
DomainC-type_lectin-like/link

ATRN ATRNL1 CD209

1.43e-0399423IPR016186
DomainPlexin_repeat

ATRN ATRNL1

2.35e-0332422IPR002165
DomainPSI

ATRN ATRNL1

2.35e-0332422PF01437
DomainGPS

ADGRG5 ADGRV1

2.65e-0334422SM00303
DomainLaminin_EGF

ATRN LAMC3

2.80e-0335422PF00053
DomainGPS

ADGRG5 ADGRV1

2.80e-0335422PF01825
DomainGPS

ADGRG5 ADGRV1

2.96e-0336422PS50221
DomainGPS

ADGRG5 ADGRV1

3.13e-0337422IPR000203
DomainMFS_dom

SLC37A2 SLC37A3 SLC15A1

3.38e-03134423IPR020846
DomainRossmann-like_a/b/a_fold

CRY2 CRY1

4.20e-0343422IPR014729
Domain-

CRY2 CRY1

4.20e-03434223.40.50.620
DomainPSI

ATRN ATRNL1

4.40e-0344422IPR016201
DomainPSI

ATRN ATRNL1

4.80e-0346422SM00423
Domain-

ATRN ATRNL1

5.22e-03484222.120.10.80
DomainCUB

ATRN ATRNL1

5.43e-0349422PF00431
DomainCUB

ATRN ATRNL1

5.65e-0350422SM00042
Domain-

ATRN ATRNL1

6.10e-03524222.60.120.290
DomainCUB

ATRN ATRNL1

6.33e-0353422PS01180
DomainKelch-typ_b-propeller

ATRN ATRNL1

6.80e-0355422IPR015915
DomainCUB_dom

ATRN ATRNL1

7.29e-0357422IPR000859
DomainEGF_extracell

ATRN ATRNL1

8.05e-0360422IPR013111
DomainEGF_2

ATRN ATRNL1

8.05e-0360422PF07974
PathwayBIOCARTA_CIRCADIAN_PATHWAY

CRY2 CRY1

8.42e-056342M22067
PathwayBIOCARTA_CIRCADIAN_PATHWAY

CRY2 CRY1

1.18e-047342MM1578
PathwayWP_EXERCISEINDUCED_CIRCADIAN_REGULATION

CRY2 NCOA4 CRY1

2.06e-0448343M39444
PathwayWP_EXERCISEINDUCED_CIRCADIAN_REGULATION

CRY2 NCOA4 CRY1

2.19e-0449343MM15870
PathwayKEGG_CIRCADIAN_RHYTHM_MAMMAL

CRY2 CRY1

4.33e-0413342M18009
PathwayPID_CIRCADIAN_PATHWAY

CRY2 CRY1

6.63e-0416342M95
Pubmed

Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling.

CRY2 AVPR1B CRY1

1.89e-08544326903624
Pubmed

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice.

CRY2 CRY1

1.56e-06244215893577
Pubmed

Circadian behavioral rhythms in Cry1/Cry2 double-deficient mice induced by methamphetamine.

CRY2 CRY1

1.56e-06244218258761
Pubmed

Delay in feedback repression by cryptochrome 1 is required for circadian clock function.

CRY2 CRY1

1.56e-06244221236481
Pubmed

CRY1, CRY2 and PRKCDBP genetic variants in metabolic syndrome.

CRY2 CRY1

1.56e-06244225391456
Pubmed

Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.

CRY2 CRY1

1.56e-06244220825493
Pubmed

The ratio of intracellular CRY proteins determines the clock period length.

CRY2 CRY1

1.56e-06244226966073
Pubmed

CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability.

CRY2 FUS

1.56e-06244237434265
Pubmed

Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice.

CRY2 CRY1

1.56e-06244224187535
Pubmed

The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.

CRY2 CRY1

1.56e-06244219211562
Pubmed

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

CRY2 CRY1

1.56e-06244228380384
Pubmed

The expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates differently dependent on tumor location.

CRY2 CRY1

1.56e-06244229940771
Pubmed

The human sugar-phosphate/phosphate exchanger family SLC37.

SLC37A2 SLC37A3

1.56e-06244212811562
Pubmed

Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.

CRY2 CRY1

1.56e-06244220042581
Pubmed

Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.

CRY2 CRY1

1.56e-06244224782829
Pubmed

Interval timing is intact in arrhythmic Cry1/Cry2-deficient mice.

CRY2 CRY1

1.56e-06244221775289
Pubmed

Control of skin cancer by the circadian rhythm.

CRY2 CRY1

1.56e-06244222025708
Pubmed

Redox potential: differential roles in dCRY and mCRY1 functions.

CRY2 CRY1

1.56e-06244211818067
Pubmed

Circadian oscillation of nucleotide excision repair in mammalian brain.

CRY2 CRY1

1.56e-06244219164551
Pubmed

Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

CRY2 CRY1

1.56e-06244210518585
Pubmed

Circadian intraocular pressure rhythm is generated by clock genes.

CRY2 CRY1

1.56e-06244216936122
Pubmed

Circadian time-place learning in mice depends on Cry genes.

CRY2 CRY1

1.56e-06244218514517
Pubmed

Altered phase-relationship between peripheral oscillators and environmental time in Cry1 or Cry2 deficient mouse models for early and late chronotypes.

CRY2 CRY1

1.56e-06244224386234
Pubmed

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.

CRY2 CRY1

1.56e-0624429822380
Pubmed

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.

CRY2 CRY1

1.56e-06244210217146
Pubmed

The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock.

CRY2 CRY1

1.56e-06244221858120
Pubmed

Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms.

CRY2 CRY1

1.56e-06244212696673
Pubmed

Serine phosphorylation of mCRY1 and mCRY2 by mitogen-activated protein kinase.

CRY2 CRY1

1.56e-06244215298678
Pubmed

Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.

CRY2 CRY1

1.56e-06244234172584
Pubmed

Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei.

CRY2 CRY1

1.56e-06244212121621
Pubmed

Expression of the blue-light receptor cryptochrome in the human retina.

CRY2 CRY1

1.56e-06244214507900
Pubmed

Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes.

CRY2 CRY1

1.56e-06244217073458
Pubmed

Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner.

CRY2 CRY1

1.56e-06244222033214
Pubmed

Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains.

CRY2 CRY1

1.56e-06244218614689
Pubmed

Light signalling in cryptochrome-deficient mice.

CRY2 CRY1

1.56e-06244214712914
Pubmed

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.

CRY2 CRY1

1.56e-06244224344304
Pubmed

Characterization of photolyase/blue-light receptor homologs in mouse and human cells.

CRY2 CRY1

1.56e-0624429801304
Pubmed

Postnatal constant light compensates Cryptochrome1 and 2 double deficiency for disruption of circadian behavioral rhythms in mice under constant dark.

CRY2 CRY1

1.56e-06244224278295
Pubmed

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice.

CRY2 CRY1

1.56e-06244223531614
Pubmed

Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer.

CRY2 CRY1

1.56e-06244216061665
Pubmed

Daily variation in the electrophysiological activity of mouse medial habenula neurones.

CRY2 CRY1

1.56e-06244224247982
Pubmed

Deregulated expression of cryptochrome genes in human colorectal cancer.

CRY2 CRY1

1.56e-06244226768731
Pubmed

Synchronization of cellular clocks in the suprachiasmatic nucleus.

CRY2 CRY1

1.56e-06244214631044
Pubmed

Autonomic and cardiovascular responses to scent stimulation are altered in cry KO mice.

CRY2 CRY1

1.56e-06244217175102
Pubmed

Genetic analysis of attractin homologs.

ATRN ATRNL1

1.56e-06244218064672
Pubmed

Network features of the mammalian circadian clock.

CRY2 CRY1

1.56e-06244219278294
Pubmed

Measurement of internal body time by blood metabolomics.

CRY2 CRY1

1.56e-06244219487679
Pubmed

Perspectives: neurobiology. The CRYs fo flies and mice.

CRY2 CRY1

1.56e-06244210636810
Pubmed

Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock.

CRY2 CRY1

1.56e-06244212483519
Pubmed

Circadian clock cryptochrome proteins regulate autoimmunity.

CRY2 CRY1

1.56e-06244229109286
Pubmed

Reduced light response of neuronal firing activity in the suprachiasmatic nucleus and optic nerve of cryptochrome-deficient mice.

CRY2 CRY1

1.56e-06244222216107
Pubmed

Further characterization of the phenotype of mCry1/mCry2-deficient mice.

CRY2 CRY1

1.56e-06244211587085
Pubmed

Cancer, hear my battle CRY.

CRY2 CRY1

1.56e-06244232291799
Pubmed

Deregulated expression of cry1 and cry2 in human gliomas.

CRY2 CRY1

1.56e-06244223317246
Pubmed

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.

CRY2 CRY1

1.56e-06244222778400
Pubmed

Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1.

CRY2 CRY1

1.56e-06244228017587
Pubmed

Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.

CRY2 CRY1

1.56e-06244232339698
Pubmed

A role for cryptochromes in sleep regulation.

CRY2 CRY1

1.56e-06244212495442
Pubmed

Restoring the Molecular Clockwork within the Suprachiasmatic Hypothalamus of an Otherwise Clockless Mouse Enables Circadian Phasing and Stabilization of Sleep-Wake Cycles and Reverses Memory Deficits.

CRY2 CRY1

1.56e-06244234446572
Pubmed

Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.

CRY2 CRY1

1.56e-0624428909283
Pubmed

CRY1 and CRY2 genetic variants in seasonality: A longitudinal and cross-sectional study.

CRY2 CRY1

1.56e-06244227267441
Pubmed

Clock gene defect disrupts light-dependency of autonomic nerve activity.

CRY2 CRY1

1.56e-06244217964540
Pubmed

Vagal regulation of respiratory clocks in mice.

CRY2 CRY1

1.56e-06244217442820
Pubmed

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.

CRY2 CRY1

1.56e-06244219940241
Pubmed

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.

CRY2 CRY1

1.56e-06244227818260
Pubmed

The involvement of Cry1 and Cry2 genes in the regulation of the circadian body temperature rhythm in mice.

CRY2 CRY1

1.56e-06244215331384
Pubmed

Circadian rhythm of RNA N6-methyladenosine and the role of cryptochrome.

CRY2 CRY1

1.56e-06244226239657
Pubmed

Cryptochromes are critical for the development of coherent circadian rhythms in the mouse suprachiasmatic nucleus.

CRY2 CRY1

1.56e-06244223575670
Pubmed

Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis.

CRY2 CRY1

4.69e-06344221628572
Pubmed

Intrinsic and extrinsic cues regulate the daily profile of mouse lateral habenula neuronal activity.

CRY2 CRY1

4.69e-06344225194046
Pubmed

Circadian regulation of food-anticipatory activity in molecular clock-deficient mice.

CRY2 CRY1

4.69e-06344223145013
Pubmed

Regulation of apoptosis by the circadian clock through NF-kappaB signaling.

CRY2 CRY1

4.69e-06344221690409
Pubmed

Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock.

CRY2 CRY1

4.69e-06344215860530
Pubmed

Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice.

CRY2 CRY1

4.69e-06344230487216
Pubmed

Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm.

CRY2 CRY1

4.69e-06344222549838
Pubmed

Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice.

CRY2 CRY1

4.69e-06344215523112
Pubmed

Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

CRY2 CRY1

4.69e-06344225707907
Pubmed

Molecular clocks in mouse skin.

CRY2 CRY1

4.69e-06344219037239
Pubmed

Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein.

CRY2 CRY1

4.69e-06344221193487
Pubmed

Suprachiasmatic nucleus grafts restore circadian behavioral rhythms of genetically arrhythmic mice.

CRY2 CRY1

4.69e-06344212699623
Pubmed

Lithium effects on circadian rhythms in fibroblasts and suprachiasmatic nucleus slices from Cry knockout mice.

CRY2 CRY1

4.69e-06344226930624
Pubmed

Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction.

CRY2 CRY1

4.69e-06344215010208
Pubmed

Circadian clock molecules CLOCK and CRYs modulate fibrinolytic activity by regulating the PAI-1 gene expression.

CRY2 CRY1

4.69e-06344216970803
Pubmed

Cell-autonomous clock of astrocytes drives circadian behavior in mammals.

CRY2 CRY1

4.69e-06344230630934
Pubmed

Quantitative analyses of cryptochrome-mBMAL1 interactions: mechanistic insights into the transcriptional regulation of the mammalian circadian clock.

CRY2 CRY1

4.69e-06344221521686
Pubmed

Loss of cryptochrome reduces cancer risk in p53 mutant mice.

CRY2 CRY1

4.69e-06344219188586
Pubmed

CRY1-CBS binding regulates circadian clock function and metabolism.

CRY2 CRY1

4.69e-06344232383312
Pubmed

Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.

CRY2 CRY1

4.69e-06344228813682
Pubmed

Reduced pupillary light responses in mice lacking cryptochromes.

CRY2 CRY1

4.69e-06344212522242
Pubmed

Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B.

CRY2 CRY1

4.69e-06344233709300
Pubmed

Cry1-/- circadian rhythmicity depends on SCN intercellular coupling.

CRY2 CRY1

4.69e-06344223223370
Pubmed

A circadian clock regulates efflux by the blood-brain barrier in mice and human cells.

CRY2 CRY1

4.69e-06344233504784
Pubmed

Circadian clock genes directly regulate expression of the Na(+)/H(+) exchanger NHE3 in the kidney.

CRY2 CRY1

4.69e-06344215780093
Pubmed

Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length.

CRY2 CRY1

4.69e-06344224158435
Pubmed

A molecular clock regulates angiopoietin-like protein 2 expression.

CRY2 CRY1

4.69e-06344223469106
Pubmed

Cryptochrome-dependent circadian periods in the arcuate nucleus.

CRY2 CRY1

4.69e-06344226542738
Pubmed

Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice.

CRY2 CRY1

4.69e-06344211114194
Pubmed

Daily variation of clock output gene activation in behaviorally arrhythmic mPer/mCry triple mutant mice.

CRY2 CRY1

4.69e-06344212916720
Pubmed

Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals.

CRY2 CRY1

4.69e-0634429600923
Pubmed

Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.

CRY2 CRY1

4.69e-06344211889036
GeneFamilySolute carriers

SLC5A11 SLC6A8 SLC37A2 SLC37A3 SLC15A1 SLC5A4

3.25e-05395296752
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ATRN ATRNL1

1.96e-03412921298
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 GCGR TECRL SPINT2 SCD5

8.78e-07178445a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 GCGR TECRL SPINT2 SCD5

8.78e-07178445b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A8 GCGR SCD5 TMEM38B ITPR1

1.48e-06198445688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCGR SPINT2 SCD5 SLC15A1

2.48e-05172444bc1b889ac5e07b8324ae5837eca911f9c865e959
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCGR SPINT2 SCD5 SLC15A1

2.48e-05172444ba70b6110b70afb1870e8dcaf58c507b8c7d918e
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 TECRL SPINT2 SCD5

2.54e-0517344445808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN MYADM PRCP GPANK1

2.54e-051734440a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 TECRL SPINT2 SCD5

2.54e-051734447fa9dbcb258c3ab974490063951620e2def03db1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A8 PTPN4 GCGR SCD5

2.90e-05179444d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A8 PTPN4 GCGR SCD5

2.90e-051794442e49b215b71438400aebb483f2c2c08d5e956961
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

SLC6A8 LHFPL6 SLC37A2 IGHV3-15

2.97e-05180444daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR ADGRV1 SCD5

2.97e-05180444a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC37A2 SLC15A1 ITPR1

2.97e-05180444a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR ADGRV1 SCD5

2.97e-05180444eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 ADGRV1 SCD5 ITPR1

3.17e-0518344431ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

COL4A5 SLC6A8 MSH6 ATRNL1

3.23e-05184444ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LHFPL6 LAMC3 GCGR ATRNL1

3.23e-05184444327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 ADGRV1 SCD5 ITPR1

3.30e-05185444898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHFPL6 ATRNL1 LRRTM4 ITPR1

3.44e-05187444f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR ADGRV1 SCD5

3.44e-0518744485e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR ADGRV1 SCD5

3.44e-0518744452b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHFPL6 ATRNL1 LRRTM4 ITPR1

3.52e-0518844450c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LAMC3 ATRNL1 LRRTM4

3.67e-051904441f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LAMC3 ATRNL1 LRRTM4

3.67e-051904442306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR SCD5 ITPR1

3.67e-051904443dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 LHFPL6 MYADM LAMC3

3.74e-05191444cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 LHFPL6 MYADM LAMC3

3.74e-05191444b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 ADGRV1 SCD5 ITPR1

3.74e-05191444963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LAMC3 ATRNL1 ITPR1

3.74e-05191444806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 MYADM PTPN4 FCRL3

3.82e-0519244458a7829b411b02b422ef75e2277a868969cc23e8
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRG5 PCSK7 PTPN4 FCRL3

3.82e-051924441922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRG5 PCSK7 PTPN4 FCRL3

3.82e-0519244497c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 MYADM PTPN4 FCRL3

3.82e-05192444ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 LHFPL6 MYADM LAMC3

3.82e-05192444e5117cdb8af220f60bd1410262078c0306667b4a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR ADGRV1 SCD5

3.82e-05192444ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRG5 PCSK7 PTPN4 FCRL3

3.82e-05192444a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 ADGRV1 SCD5 ITPR1

3.82e-05192444562df5e87038c500dd3a003fe5374cb31946b145
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRAPPC10 PTPN4 FUS FCRL3

4.06e-051954440a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN4 GCGR SCD5 TMEM38B

4.22e-051974444ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRY2 LHFPL6 MYADM RECK

4.39e-0519944467f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRY2 LHFPL6 MYADM RECK

4.39e-051994441ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL4A5 LHFPL6 ATRNL1 ITPR1

4.48e-052004448988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

COL4A5 LHFPL6 ATRNL1 ITPR1

4.48e-0520044487827041663013f5e7273168dc8709d69840e7ce
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

ADGRG5 PTPN4 GCGR

8.73e-0587443fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC5A11 COL4A5 SCD5

1.40e-041024430bbc6344d0baee47326a16a89773bb5c68a7b040
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC5A11 COL4A5 SCD5

1.40e-0410244311fbdb428824023603e9d4ee41e957ba84e7c29e
ToppCellControl-CD4+_T_activated|Control / Disease condition and Cell class

LINC00114 DNAH5 ATRNL1

2.05e-04116443e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LINC00114 DNAH5 ATRNL1

2.15e-04118443f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LINC00114 DNAH5 ATRNL1

2.15e-041184430dcac16eea8e7978de370a815da9a0cdd212598e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LINC00114 DNAH5 ATRNL1

2.15e-041184437da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LINC00114 DNAH5 ATRNL1

2.15e-04118443c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCellControl-Lymphoid_T/NK-CD4+_T_activated|Control / Disease group, lineage and cell class

LINC00114 DNAH5 ATRNL1

2.21e-04119443d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-5|TCGA-Brain / Sample_Type by Project: Shred V9

ADGRV1 SCD5 LRRTM4

3.34e-04137443a7c76201b8901b2ef7ebbb4dfe0cec0dc4534ef5
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GCGR SPINT2 DNAH5

3.41e-04138443615822e542f12aa83df1561e262b8d72bdefc60e
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC5A11 SLC6A8 GCGR

3.86e-0414444375b16adfbe84f69376e6566d531ba7919d5c5192
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LINC00114 ATRNL1

3.94e-04145443051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A11 SLC37A2 SLC15A1

4.10e-04147443a5ed71afe5fcb4f541080f5552252695c7d4d090
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A11 SLC37A2 SLC15A1

4.27e-041494437726957b1de638c3bfc659381d15eab626bb179b
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC37A2 SLC15A1

4.44e-04151443a306e8dac653bc785d805d8d2d94feec3cb01727
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRAPPC10 ADGRG5 PTPN4

4.61e-04153443d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL4A5 LAMC3 GCGR

4.70e-0415444365dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC37A2 GCGR TMEM186

4.79e-041554435fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LHFPL6 LAMC3 ATRNL1

4.88e-041564436365b69ede98bc866e996bc52736b00401aacf6f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

FUS LRRTM4 CRY1

4.88e-041564431545169694f686d28648a68b552c2ae606599d66
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LHFPL6 LAMC3 ATRNL1

4.97e-04157443bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

ADGRG5 PTPN4 FUS

5.25e-04160443ab633295cb4de88fdbc076295e1352769f47cc00
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN4 SCD5 TARBP1

5.25e-041604436b0faaa371650563f585722f5b2fb319e124ec38
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|367C / Donor, Lineage, Cell class and subclass (all cells)

ADGRG5 PTPN4 FCRL3

5.35e-04161443f7dc1e3326ab22f2eb1e94b632469a0682a3289c
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TECRL SPINT2 SCD5

5.45e-04162443d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

COL4A5 LAMC3 DNAH5

5.45e-0416244391cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCOA4 LINC00114 RECK

5.45e-0416244325a11e4c6304324310b33a33331ebc812d045d4a
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TECRL SPINT2 SCD5

5.45e-0416244306f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

PCSK7 FUS ITPR1

5.45e-04162443b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 COL4A5 SCD5

5.45e-04162443b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC37A2 SLC15A1

5.45e-04162443bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

LHFPL6 ADGRV1 DNAH5

5.54e-04163443e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYADM FCRL3 ITPR1

5.54e-041634436bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell390C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCD5 DNAH5 TARBP1

5.64e-041644432957065d7f1332c5280d47be7cc342286f84be3e
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A5 ATRNL1 LRRTM4

5.64e-04164443e3983f655cdba308fb192182829f17bef99ce0ba
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

ADGRG5 PTPN4 DNAH5

5.64e-0416444360fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCell390C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCD5 DNAH5 TARBP1

5.64e-0416444382e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC37A2 SPINT2 ITPR1

5.85e-041664431ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Heart-nan-18m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL6 MSH6 ADGRV1

5.85e-041664439adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC37A2 SPINT2 ITPR1

5.85e-041664434cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLC37A2 TMEM38B CD209

5.95e-04167443a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRG5 PTPN4 FCRL3

6.05e-04168443696b31bedbc7d40817a733e8c6ec2633404be619
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SLC37A2 SLC15A1

6.05e-0416844303896466698a79f7f1ad862cb7e05585260e2a5a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LAMC3 ATRNL1

6.05e-04168443d19a115365c5415e51c039718d7669de788fcf33
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 PTPN4 FCRL3

6.05e-04168443240ea32b64d86f9216785010d6b237d9adf052c9
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 SPINT2 SCD5

6.05e-0416844396f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 PTPN4 FCRL3

6.05e-04168443b4bb03efb601a61465260f93896c56861c588bef
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 PTPN4 FCRL3

6.16e-04169443e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 LAMC3 ATRNL1

6.16e-04169443a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

SLC37A2 TMEM38B CD209

6.26e-041704433a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG5 PTPN4 RECK

6.26e-04170443070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SPINT2 SLC15A1

6.37e-04171443b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 LAMC3 DNAH5

6.37e-041714435447b78148f7bccb727e2fc108589b2af02a5d31
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

LHFPL6 LAMC3 LRRTM4

6.37e-04171443080003f698f867935c2bfc55d241d3650f45a0ab
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A8 SPINT2 SLC15A1

6.37e-04171443e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 LAMC3 DNAH5

6.48e-04172443a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
DrugBrij 35

PCSK7 GCGR ZP2 ICMT

1.03e-0572434CID000024750
DrugUn9

CRY2 CRY1

1.04e-053432CID006914666
DiseaseSeasonal Affective Disorder

CRY2 CRY1

2.46e-0416432C0085159
DiseaseCiliopathies

ADGRV1 DNAH5 RPE65

5.58e-04110433C4277690
DiseaseMyeloid Leukemia, Chronic

CRY2 CRY1

8.21e-0429432C0023473
DiseaseThyroid Gland Follicular Adenoma

MSH6 NCOA4

1.20e-0335432C0151468
DiseaseThyroid Neoplasm

MSH6 NCOA4

1.34e-0337432C0040136

Protein segments in the cluster

PeptideGeneStartEntry
MQTTWQPGCSYPTSW

LINC00114

1

Q6XXX2
SASEGPQCFWMTSWI

ADGRV1

2456

Q8WXG9
PQCFWMTSWISPAVN

ADGRV1

2461

Q8WXG9
MTSWISPAVNNSDFW

ADGRV1

2466

Q8WXG9
CPWEWTFFQGNCYFM

CD209

256

Q9NNX6
MSWGNTQSWQEFDRF

RECK

311

O95980
PHTCTDFWQMTWEQG

PTPN4

731

P29074
NMWECSRSICPLFYW

LRRTM4

311

Q86VH4
INARDAFWWTPLMCA

GPANK1

136

O95872
AFWWTPLMCAARAGQ

GPANK1

141

O95872
FTFSNAWMSWVRQAP

IGHV3-15

46

A0A0B4J1V0
QPVLYWCARNMSFWS

ITPR1

2271

Q14643
WKCPNPTCENMNFSW

FUS

426

P35637
YWCWEDMSPFTNSLL

ATRN

866

O75882
PNGFNDWTFSTVRCW

PCSK7

566

Q16549
TSNDNMGFWWILRFP

GCGR

296

P47871
IIWFCNNTGFMWDVA

PRCP

96

P42785
NWSMFTWCFCFSVTL

MYADM

66

Q96S97
DFLNSCTPGMRKWWQ

MSH6

401

P52701
ATSCVGFFMPYWLWG

LHFPL6

21

Q9Y693
PMNTSWCSFNTADWV

NCOA4

526

Q13772
SLNDTMWCSWAPFDK

SLC37A2

66

Q8TED4
WFYWSIGTQVMLCNP

ICMT

216

O60725
VNAGSWMWLSCSAFF

CRY2

411

Q49AN0
CPQGWDSLWIGYSFM

COL4A5

1586

P29400
SWMWLSCSSFFQQFF

CRY1

396

Q16526
WGWEDMSPFTNTTLQ

ATRNL1

821

Q5VV63
QIPAMWTEDSGSYWC

FCRL3

246

Q96P31
PMFWALFDQQGSRWT

SLC15A1

291

P46059
WVFNGRPHCFWMTGF

DNAH5

4471

Q8TE73
SSWSLWGANYMDCFE

RPE65

266

Q16518
FGMPITALWYWCTNQ

SLC5A4

281

Q9NY91
FGMSIPSLWYWCTDQ

SLC5A11

276

Q8WWX8
FNPTTWFIDFMCWLG

SCD5

291

Q86SK9
WCWSFFTPLVCMGIF

SLC6A8

521

P48029
SWENGTGFQNMSICW

ADGRG5

391

Q8IZF4
IACWAPFFSVQMWSV

AVPR1B

291

P47901
STGWPCVVAVMGNWF

SLC37A3

156

Q8NCC5
MPRWWYNVTDGSCQL

SPINT2

51

O43291
NFWGWRQDTYCPMAD

TMEM186

146

Q96B77
FEDTLSWMLFGWQQP

TMEM38B

236

Q9NVV0
SWMLFGWQQPFSSCE

TMEM38B

241

Q9NVV0
FNWLARDMASPNWSI

TBCC

321

Q15814
SSAWETGENCFMPDW

TARBP1

616

Q13395
NLIMSCAFYWGFTSW

TECRL

216

Q5HYJ1
ANWLTFFCQPVKSWN

TRAPPC10

266

P48553
WATSTMDPDSFPQWN

ZP2

546

Q05996
SQDESTWWQSPSMAF

LAMC3

96

Q9Y6N6