Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST4 NDST3 NDST1	4.23e-06	4	205	3	GO:0015016
GeneOntologyMolecularFunction	N-acetylglucosamine deacetylase activity	NDST4 NDST3 NDST1	4.23e-06	4	205	3	GO:0050119
GeneOntologyMolecularFunction	deaminase binding	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.23e-06	4	205	3	GO:1990827
GeneOntologyMolecularFunction	heparan sulfate N-deacetylase activity	NDST3 NDST1	3.13e-04	3	205	2	GO:0102140
GeneOntologyMolecularFunction	N6-methyladenosine-containing RNA reader activity	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.43e-04	15	205	3	GO:1990247
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	NDST4 NDST3 NDST1	4.43e-04	15	205	3	GO:0034483
GeneOntologyBiologicalProcess	negative regulation of mRNA modification	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.71e-05	6	198	3	GO:0090367
GeneOntologyBiologicalProcess	regulation of mRNA modification	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.96e-05	7	198	3	GO:0090365
GeneOntologyBiologicalProcess	cell-cell adhesion	DCHS2 MCAM NCAM2 GFUS FAT2 NRXN1 PKD1 FGB PKP2 ASTN2 PCDHB1 DPP4 FAT4 RAP2B PCDHGB5 WNT5A FAT3 SHB CLDN7 CLSTN1 IGDCC4 ARID2 PRKCD CTNNA1 CTNND2	4.00e-05	1077	198	25	GO:0098609
GeneOntologyBiologicalProcess	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	NDST4 NDST3 NDST1	4.71e-05	8	198	3	GO:0015014
GeneOntologyCellularComponent	nucleoplasmic periphery of the nuclear pore complex	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.82e-05	6	205	3	GO:1990826
GeneOntologyCellularComponent	TRC complex	SGTB SGTA	9.57e-05	2	205	2	GO:0072380
GeneOntologyCellularComponent	cell-cell junction	DCHS2 AQP7P3 FAT2 NRXN1 SCN5A PKP2 DPP4 RAP2B CLDN7 KRIT1 PDLIM4 LMO7 PRKCD CTNNA1 CTNND2 RAP2C	2.52e-04	591	205	16	GO:0005911
Domain	Heparan_SO4_deacetylase	NDST4 NDST3 NDST1	4.66e-06	4	198	3	IPR021930
Domain	HSNSD	NDST4 NDST3 NDST1	4.66e-06	4	198	3	PF12062
Domain	hnRNP_C	HNRNPCL1 HNRNPCL4 HNRNPCL2	2.29e-05	6	198	3	IPR017347
Domain	-	FAT2 NRXN1 FAT4 COL12A1 FAT3 CLSTN1 PAPPA	6.80e-05	95	198	7	2.60.120.200
Domain	SGTA_dimer	SGTB SGTA	1.12e-04	2	198	2	IPR032374
Domain	SGTA_dimer	SGTB SGTA	1.12e-04	2	198	2	PF16546
Domain	ConA-like_dom	RYR1 FAT2 NRXN1 SEL1L3 RANBP10 FAT4 COL12A1 FAT3 CLSTN1 PAPPA	1.19e-04	219	198	10	IPR013320
Domain	CADHERIN_1	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.03e-04	113	198	7	PS00232
Domain	Cadherin	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.03e-04	113	198	7	PF00028
Domain	CADHERIN_2	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.14e-04	114	198	7	PS50268
Domain	-	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.14e-04	114	198	7	2.60.40.60
Domain	CA	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.26e-04	115	198	7	SM00112
Domain	Cadherin-like	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.38e-04	116	198	7	IPR015919
Domain	TPR_8	TMTC3 OGT TTC28 SGTA IFIT1	2.42e-04	53	198	5	PF13181
Domain	Cadherin	DCHS2 FAT2 PCDHB1 FAT4 PCDHGB5 FAT3 CLSTN1	2.65e-04	118	198	7	IPR002126
Domain	Laminin_G	FAT2 NRXN1 FAT4 COL12A1 FAT3	3.70e-04	58	198	5	IPR001791
Domain	-	ZGRF1 NDST4 DNAH14 NDST3 ABCG4 ABCC1 NDST1 RAP2A RAP2B DDX60 INO80 RFC2 RAB20 SBNO2 ATAD3A DHX32 AGAP9 RAP2C TDRD12	3.82e-04	746	198	19	3.40.50.300
Domain	TPR_1	TMTC3 OGT SGTB TTC28 SGTA IFIT1	3.91e-04	90	198	6	IPR001440
Domain	TPR_1	TMTC3 OGT SGTB TTC28 SGTA IFIT1	3.91e-04	90	198	6	PF00515
Domain	LAM_G_DOMAIN	FAT2 NRXN1 FAT4 FAT3	6.82e-04	38	198	4	PS50025
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 DNAJA2 NCAM2 FMNL2 GTF3C4 MICU1 SCG2 MIB1 PKD1 ASTN2 ALAD CARS2 PLP1 NDST1 OGT HDAC6 SGTB COPA TTC28 PPFIBP1 SYNE1 SGTA MED13L KRIT1 LMO7 CTNNA1 CTNND2 ZBTB11 GEN1 SLX4	2.01e-10	1285	208	30	35914814
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT2 FAT4 FAT3	4.29e-08	7	208	4	16059920
Pubmed	Mutagenesis analysis of human SM22: characterization of actin binding.	ACTA1 TAGLN PRKCD	2.11e-07	3	208	3	11053353
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	HNRNPCL1 KDM3B HNRNPCL3 SLC25A32 AP1B1 HNRNPCL4 C4A C4B WDR48 OGT TTC28 RBL1 PPFIBP1 CLSTN1 SBNO2 HSD17B12 ZBTB11	4.54e-07	650	208	17	38777146
Pubmed	Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.	RAP2A RAP2B RAP2C	8.40e-07	4	208	3	16540189
Pubmed	hnRNPC induces isoform shifts in miR-21-5p leading to cancer development.	HNRNPCL1 HNRNPCL3 HNRNPCL2	8.40e-07	4	208	3	35729324
Pubmed	N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.	HNRNPCL1 HNRNPCL3 HNRNPCL2	8.40e-07	4	208	3	36681355
Pubmed	hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability.	HNRNPCL1 HNRNPCL3 HNRNPCL2	8.40e-07	4	208	3	10805751
Pubmed	Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.	NDST4 NDST3 NDST1	8.40e-07	4	208	3	22049073
Pubmed	The splicing factor hnRNP C regulates expression of co-stimulatory molecules CD80 and CD40 in dendritic cells.	HNRNPCL1 HNRNPCL3 HNRNPCL2	8.40e-07	4	208	3	23831410
Pubmed	Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.	NDST4 NDST3 NDST1	8.40e-07	4	208	3	12070138
Pubmed	Recurrent CNVs disrupt three candidate genes in schizophrenia patients.	NRXN1 ASTN2 CTNND2	8.40e-07	4	208	3	18940311
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KDM3B HEPH NRXN1 SRGAP3 WDR48 TTC28 PPFIBP1 SYNE1 MED13L LMO7	1.16e-06	225	208	10	12168954
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	RYR1 GLA SCN5A PKP2 PRKAG2 APOB	1.20e-06	57	208	6	23788249
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HNRNPCL1 DNAJA2 ACTA1 NCAM2 FMNL2 HNRNPCL3 NF1 AP1B1 SRGAP3 C4A C4B PRKAG2 PLP1 HNRNPCL2 RAP2B OGT COPA SYNE1 CARMIL1 NCKIPSD LMO7 ATAD3A CTNNA1 CTNND2 TNS1	1.73e-06	1431	208	25	37142655
Pubmed	Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration.	RAP2A RAP2B RAP2C	2.09e-06	5	208	3	35293963
Pubmed	Heterogeneous nuclear ribonucleoprotein C1 may control miR-30d levels in endometrial exosomes affecting early embryo implantation.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.09e-06	5	208	3	29846695
Pubmed	Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.09e-06	5	208	3	25809670
Pubmed	Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene.	HNRNPCL1 HNRNPCL3 HNRNPCL2	2.09e-06	5	208	3	9128719
Pubmed	Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.	NDST4 NDST3 NDST1	2.09e-06	5	208	3	11087757
Pubmed	Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.	DCHS2 FAT2 FAT4 FAT3	3.56e-06	18	208	4	33108146
Pubmed	Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease.	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.16e-06	6	208	3	26048669
Pubmed	Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.16e-06	6	208	3	15687492
Pubmed	Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis.	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.16e-06	6	208	3	18363099
Pubmed	Selective disruption of genes expressed in totipotent embryonal stem cells.	HNRNPCL1 HNRNPCL3 HNRNPCL2	4.16e-06	6	208	3	1317320
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CENPC DNAJA2 PICALM GTF3C4 MICU1 MIB1 FGB WDR48 COL12A1 HDAC6 PPFIBP1 NCKIPSD TRMT6 AKAP9 JRK BUB3	4.58e-06	689	208	16	36543142
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPCL1 HNRNPCL3 HNRNPCL2	7.25e-06	7	208	3	25846207
Pubmed	FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.	NDST4 NDST3 NDST1	1.15e-05	8	208	3	24067353
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	HNRNPCL1 HNRNPCL3 HNRNPCL2 CTNNA1	1.68e-05	26	208	4	15890332
Pubmed	Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization.	HNRNPCL1 HNRNPCL3 HNRNPCL2	1.72e-05	9	208	3	10452948
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	HNRNPCL1 HNRNPCL3 PRKAG2 HNRNPCL2 OGT SALL4 ATAD3A	1.79e-05	135	208	7	31077711
Pubmed	Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.	NDST4 NDST3 NDST1	3.36e-05	11	208	3	15944372
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	KDM3B RYR1 FER1L6 NF1 TMTC3 AP1B1 MIB1 FAT4 MXRA5 TTC28 MUC16 IFIT1 ARID2 CTNND2	3.40e-05	638	208	14	31182584
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	3.56e-05	2	208	2	19062096
Pubmed	Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell cultures.	WNT5A PRKCD	3.56e-05	2	208	2	21911383
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	3.56e-05	2	208	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	3.56e-05	2	208	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	3.56e-05	2	208	2	27758680
Pubmed	Upregulation of USP22 and ABCC1 during Sorafenib Treatment of Hepatocellular Carcinoma Contribute to Development of Resistance.	ABCC1 USP22	3.56e-05	2	208	2	35203285
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	3.56e-05	2	208	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	3.56e-05	2	208	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	3.56e-05	2	208	2	4216347
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	3.56e-05	2	208	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	3.56e-05	2	208	2	24638111
Pubmed	Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.	PKD1 HDAC6	3.56e-05	2	208	2	28887310
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	3.56e-05	2	208	2	21345967
Pubmed	The complement component C4 of mammals.	C4A C4B	3.56e-05	2	208	2	2302180
Pubmed	CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.	MCAM DCBLD2	3.56e-05	2	208	2	37856423
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	3.56e-05	2	208	2	22151770
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	3.56e-05	2	208	2	29080553
Pubmed	Anti-Metastatic and Anti-Invasion Effects of a Specific Anti-MUC18 scFv Antibody on Breast Cancer Cells.	MCAM WNT5A	3.56e-05	2	208	2	27565656
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	3.56e-05	2	208	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	3.56e-05	2	208	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	3.56e-05	2	208	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	3.56e-05	2	208	2	6149581
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	3.56e-05	2	208	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	3.56e-05	2	208	2	2387317
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	3.56e-05	2	208	2	7365238
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	3.56e-05	2	208	2	17971360
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	3.56e-05	2	208	2	17971229
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	3.56e-05	2	208	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	3.56e-05	2	208	2	28873507
Pubmed	Correlations Between the Genetic Variations in the COL1A1, COL5A1, COL12A1, and β-fibrinogen Genes and Anterior Cruciate Ligament Injury in Chinese Patientsa.	FGB COL12A1	3.56e-05	2	208	2	32239963
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	3.56e-05	2	208	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	3.56e-05	2	208	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	3.56e-05	2	208	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	3.56e-05	2	208	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	3.56e-05	2	208	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	3.56e-05	2	208	2	7373044
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	3.56e-05	2	208	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	3.56e-05	2	208	2	16098595
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	3.56e-05	2	208	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	3.56e-05	2	208	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	3.56e-05	2	208	2	6559257
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	3.56e-05	2	208	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	3.56e-05	2	208	2	26800705
Pubmed	Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation.	WNT5A PRKCD	3.56e-05	2	208	2	19492056
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	3.56e-05	2	208	2	1699796
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	3.56e-05	2	208	2	2997024
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	3.56e-05	2	208	2	3624865
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	3.56e-05	2	208	2	30041577
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	3.56e-05	2	208	2	3862104
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL2 FMNL3	3.56e-05	2	208	2	28327544
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	3.56e-05	2	208	2	26814963
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	3.56e-05	2	208	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	3.56e-05	2	208	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	3.56e-05	2	208	2	26814708
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	3.56e-05	2	208	2	1438267
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	3.56e-05	2	208	2	19150565
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	3.56e-05	2	208	2	17506029
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	3.56e-05	2	208	2	23715124
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	3.56e-05	2	208	2	2993295
Pubmed	A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein.	SGTB SGTA	3.56e-05	2	208	2	12878599
Pubmed	Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.	C4A C4B	3.56e-05	2	208	2	33353966
Pubmed	Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.	C4A C4B	3.56e-05	2	208	2	2900855
Pubmed	Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.	PKD1 PAPPA	3.56e-05	2	208	2	31990681
Pubmed	Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.	C4A C4B	3.56e-05	2	208	2	23259761
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	3.56e-05	2	208	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	3.56e-05	2	208	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	3.56e-05	2	208	2	15998580
Cytoband	2q35-q36	SCG2 TNS1	1.22e-04	4	208	2	2q35-q36
GeneFamily	Cadherin related	DCHS2 FAT2 FAT4 FAT3 CLSTN1	1.54e-07	17	141	5	24
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TMTC3 OGT SGTB TTC28 SGTA IFIT1	2.83e-04	115	141	6	769
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_k-means-cluster#3_top-relative-expression-ranked_1000	CNPY4 BIVM EML5 PTBP3 HDAC6 WNT5A FAT3 CARMIL1 SALL4 VPS36 CLDN7 ROS1 CTNND2	2.72e-07	227	201	13	gudmap_kidney_e10.5_UretericTip_HoxB7_k3_1000
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_1000	EML5 SEL1L3 PKP2 KLHL14 RASGRF2 SALL4 CLDN7 RAB20 ROS1 CTNND2	1.11e-05	185	201	10	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k4
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#1_top-relative-expression-ranked_1000	CNPY4 BIVM EML5 PTBP3 HDAC6 WNT5A CARMIL1 SALL4 VPS36 CLDN7 ROS1	1.51e-05	234	201	11	gudmap_kidney_e10.5_UretericTrunk_HoxB7_k1_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_1000	EML5 SEL1L3 PKP2 KLHL14 RASGRF2 CLDN7 RAB20 ROS1	2.42e-05	124	201	8	gudmap_developingKidney_e15.5_cortic collect duct_1000_k3
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP26A1 MCAM NDUFA4L2 TAGLN COL6A3 MXRA5 COL12A1 RASGRF2 WNT5A SALL4	2.57e-08	193	207	10	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FRMPD4 MCAM NDST4 NDUFA4L2 NDST3 TAGLN PLP1 COL12A1 WNT5A ZFHX3	2.69e-08	194	207	10	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF NDST4 NCAM2 HEPH COL6A3 FAT4 MXRA5 SYNE1 PAPPA CHSY3	3.59e-08	200	207	10	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 NCAM2 NRXN1 FAT4 COL12A1 FAT3 SALL4 APOB ROS1	2.12e-07	184	207	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 NCAM2 NRXN1 FAT4 COL12A1 FAT3 SALL4 APOB ROS1	2.12e-07	184	207	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 NCAM2 NRXN1 FAT4 COL12A1 FAT3 SALL4 APOB ROS1	2.12e-07	184	207	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FRMPD4 MCAM NDST4 NDST3 TAGLN PLP1 COL12A1 WNT5A ZFHX3	3.17e-07	193	207	9	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DGKH FAT2 TMTC3 SRGAP3 CLDN7 CLSTN1 AKAP9 LMO7 CTNNA1	4.28e-07	200	207	9	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DGKH FAT2 SRGAP3 MUC16 CLDN7 CLSTN1 AKAP9 LMO7 CTNNA1	4.28e-07	200	207	9	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ACTA1 RYR1 FGB PLP1 COL28A1 SALL4 APOB	7.45e-07	157	207	8	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ACTA1 RYR1 FGB PLP1 COL28A1 SALL4 APOB	7.45e-07	157	207	8	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF ACTA1 RYR1 FGB PLP1 COL28A1 SALL4 APOB	7.45e-07	157	207	8	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DNAH14 PDZRN4 DPP4 COL12A1 SHB ZFHX3 ROS1	1.30e-06	169	207	8	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	droplet-Lung-nan-21m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP8B1 PPM1M RYR1 SRGAP3 OTULINL DPP4 NCKIPSD CTNND2	1.36e-06	170	207	8	71c52fadecc6b4bfe98692b266adaa1406f6d56d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 MCAM DGKH ADCY5 NRXN1 PCDHGB5 FAT3 PAPPA	1.36e-06	170	207	8	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	NCAM2 NRXN1 ASTN2 PLP1 COL28A1 DTD2 PAPPA CTNND2	1.55e-06	173	207	8	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADCY5 TAGLN PLP1 COL6A3 FAT4 COL12A1 WNT5A APOB	2.17e-06	181	207	8	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	moderate-Lymphoid-NK\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KCNJ13 TAGLN PLP1 MLANA COL6A3 FAT4 COL12A1 PAPPA	2.55e-06	185	207	8	4979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 RPTN MIB1 PKD1 PKP2 PEX11G CLDN7 PIERCE1	2.76e-06	187	207	8	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 RPTN MIB1 PKD1 PKP2 PEX11G CLDN7 PIERCE1	2.76e-06	187	207	8	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 RPTN MIB1 PKD1 PKP2 PEX11G CLDN7 PIERCE1	2.76e-06	187	207	8	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP26A1 TAGLN COL6A3 MXRA5 COL12A1 RASGRF2 WNT5A SALL4	3.36e-06	192	207	8	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NDST4 HEPH NDST3 COL6A3 FAT4 COL12A1 WNT5A FAT3	3.36e-06	192	207	8	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SRGAP3 COL6A3 FAT4 RAP2B TTC28 PPFIBP1 FAT3 CARMIL1	3.63e-06	194	207	8	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HGF SRGAP3 COL6A3 FAT4 TTC28 PPFIBP1 FAT3 CARMIL1	3.77e-06	195	207	8	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCAM NDUFA4L2 NRXN1 OTULINL TAGLN PDZRN4 COL12A1 WNT5A	3.91e-06	196	207	8	acbb493dbb49a33f20cf11106363f7ed51209706
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGF MCAM NDUFA4L2 DGKH ADCY5 TAGLN PDZRN4 ZFHX3	3.91e-06	196	207	8	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	NCAM2 FMNL2 PDZRN4 ABCC1 COL6A3 CARMIL1 PAPPA ZFHX3	3.91e-06	196	207	8	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP26A1 FER1L6 RPTN ERICH3 MUC16 CLSTN1 LMO7 CTNNA1	4.06e-06	197	207	8	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	MCAM NDUFA4L2 DGKH ADCY5 ITIH3 TAGLN ZFHX3 TNS1	4.22e-06	198	207	8	89986c7756541df364df516329d10775ba0e78a4
ToppCell	background-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HGF ITIH3 FGB TAGLN COL6A3 MXRA5 FAT3 CHSY3	4.22e-06	198	207	8	79f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ACTA1 MCAM ADCY5 ABCG4 TAGLN FAT3 GRIK5 TNS1	4.22e-06	198	207	8	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	HGF ADCY5 TAGLN COL6A3 MXRA5 COL12A1 FAT3 CHSY3	4.22e-06	198	207	8	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ACTA1 MCAM NDUFA4L2 ADCY5 ITIH3 TAGLN COL12A1 TNS1	4.38e-06	199	207	8	9a08c25bb4851ad4ac9db8916422280f71378c2c
ToppCell	metastatic_Brain-Fibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	MCAM NDUFA4L2 HEPH SCG2 TAGLN COL6A3 MXRA5 PAPPA	4.38e-06	199	207	8	63eb2106bb6e2e33d020628583536c8d96662c84
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 CYP26A1 DGKH PDZRN4 DPP4 SHB ZFHX3 ROS1	4.54e-06	200	207	8	501cd2b4e55444fc5fdd93ebbcfc0616442b110b
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP8B1 CYP26A1 ITIH3 FGB SARDH SERPINA7 APOB	6.95e-06	151	207	7	e243b6c76e59035f10519a86399b598dd2123f87
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP8B1 CYP26A1 ITIH3 FGB SARDH SERPINA7 APOB	6.95e-06	151	207	7	cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	NDST4 NCAM2 RYR1 NRXN1 PDZRN4 FAT3 CTNND2	9.74e-06	159	207	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DGKH PDZRN4 DPP4 SHB ZFHX3 ROS1	1.29e-05	166	207	7	739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 CYP26A1 DGKH PDZRN4 DPP4 ZFHX3 ROS1	1.34e-05	167	207	7	a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NCAM2 NRXN1 ASTN2 PLP1 COL28A1 PAPPA CTNND2	1.39e-05	168	207	7	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 SEL1L3 PLP1 COL28A1 RAB20 PDLIM4 PAPPA	1.39e-05	168	207	7	af82e07d1eec51fc6530155f37addbce6221885d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DGKH PDZRN4 DPP4 SHB ZFHX3 ROS1	1.39e-05	168	207	7	217770a94ace446cdfc7687b459dece707576e76
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DGKH HNRNPCL2 DPP4 COL12A1 SHB ZFHX3 ROS1	1.45e-05	169	207	7	ccb7b2daa65cb5f4c1e7a48b3bcdf0cb8f7675c3
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 SRGAP3 TSSK3 CARMIL1 NCKIPSD CTNND2 TNS1	1.56e-05	171	207	7	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 SRGAP3 TSSK3 CARMIL1 NCKIPSD CTNND2 TNS1	1.56e-05	171	207	7	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DGKH PDZRN4 DPP4 FAT4 ZFHX3 ROS1	1.62e-05	172	207	7	cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell	facs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRA8 RYR1 STAT2 SRGAP3 SARDH CTNND2 TNS1	1.68e-05	173	207	7	ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP8B1 PPM1M FMNL2 SRGAP3 DPP4 CLDN7 CHSY3	1.68e-05	173	207	7	70c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCell	facs-Marrow-T-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRA8 RYR1 STAT2 SRGAP3 SARDH CTNND2 TNS1	1.68e-05	173	207	7	19a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCAM ADCY5 TAGLN PDZRN4 FAT3 ZFHX3 TNS1	1.68e-05	173	207	7	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HEPH NRXN1 STRADA ASTN2 SARDH PLP1	1.72e-05	116	207	6	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 SEL1L3 PDZRN4 DPP4 LMO7 ZFHX3 ROS1	1.75e-05	174	207	7	e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DNAH14 PDZRN4 DPP4 FAT4 ZFHX3 ROS1	1.75e-05	174	207	7	7d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TAGLN COL6A3 FAT4 COL12A1 WNT5A PAPPA TNS1	1.81e-05	175	207	7	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPC ZGRF1 MCAM NDUFA4L2 NDST3 NRXN1 ZFHX3	1.81e-05	175	207	7	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1M FMNL2 PMPCA SRGAP3 DPP4 TTLL4 CTNND2	1.88e-05	176	207	7	6b4afd2c9268172063fe5832896bea15e862579e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 CYP26A1 DGKH PDZRN4 DPP4 ZFHX3 ROS1	1.88e-05	176	207	7	ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell	wk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	EML5 NRXN1 SCG2 SCN5A PKP2 PDZRN4 BUB3	1.95e-05	177	207	7	15a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HEPH NF1 EML5 SEL1L3 PAN2 TAGLN TTLL4	1.95e-05	177	207	7	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	MCAM ITIH3 TAGLN PDZRN4 CARMIL1 RAB20 ZFHX3	2.10e-05	179	207	7	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLP1 COL6A3 MXRA5 COL12A1 WNT5A IGDCC4 PAPPA	2.17e-05	180	207	7	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLP1 COL6A3 MXRA5 COL12A1 WNT5A IGDCC4 PAPPA	2.17e-05	180	207	7	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	MCAM ADCY5 TAGLN PDZRN4 FAT3 ZFHX3 TNS1	2.17e-05	180	207	7	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 PLP1 COL12A1 RAP2B CLSTN1 PDLIM4 PAPPA	2.33e-05	182	207	7	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KCNJ13 TAGLN PLP1 MLANA COL6A3 COL12A1 PAPPA	2.33e-05	182	207	7	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLP1 COL6A3 MXRA5 COL12A1 WNT5A IGDCC4 PAPPA	2.42e-05	183	207	7	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLP1 COL6A3 MXRA5 COL12A1 WNT5A IGDCC4 PAPPA	2.42e-05	183	207	7	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLP1 COL6A3 MXRA5 COL12A1 WNT5A IGDCC4 PAPPA	2.42e-05	183	207	7	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCAM ADCY5 ITIH3 TAGLN PDZRN4 SYNE1 ZFHX3	2.68e-05	186	207	7	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	MCAM ADCY5 TAGLN PDZRN4 COL6A3 COL12A1 TTC28	2.77e-05	187	207	7	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MCAM NDST4 NDST3 TAGLN PLP1 WNT5A ZFHX3	2.77e-05	187	207	7	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP3 SEL1L3 ASTN2 DPP4 PPFIBP1 CLSTN1 ZNF69	2.77e-05	187	207	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Pericytes-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	MCAM NDUFA4L2 HEPH TAGLN COL6A3 COL12A1 PAPPA	2.87e-05	188	207	7	f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DGKH FMNL2 CARS2 PCDHGB5 IFIT1 ARID2 TTLL4	2.87e-05	188	207	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DGKH FMNL2 CARS2 PCDHGB5 IFIT1 ARID2 TTLL4	2.87e-05	188	207	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DGKH FMNL2 CARS2 PCDHGB5 IFIT1 ARID2 TTLL4	2.87e-05	188	207	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 SCN5A NKPD1 PLP1 PPFIBP1 PDLIM4 BUB3	2.87e-05	188	207	7	9fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MCAM NCAM2 NDST3 PLP1 COL28A1 PDLIM4 SLC5A11	2.87e-05	188	207	7	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 SCN5A NKPD1 PLP1 PPFIBP1 PDLIM4 BUB3	2.87e-05	188	207	7	459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell	P07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NDUFA4L2 ADCY5 ITIH3 TAGLN TNFSF15 PDLIM4 ZFHX3	2.87e-05	188	207	7	6ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCAM ADCY5 ITIH3 TAGLN PDZRN4 CARMIL1 ZFHX3	2.97e-05	189	207	7	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MCAM NDST4 NDST3 TAGLN PLP1 WNT5A ZFHX3	2.97e-05	189	207	7	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	HGF MCAM NDUFA4L2 TAGLN PDZRN4 COL12A1 ZFHX3	3.18e-05	191	207	7	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DGKH DNAH14 SRGAP3 SEL1L3 ASTN2 PPFIBP1 FAT3	3.18e-05	191	207	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	NCAM2 FMNL2 COL6A3 COL12A1 CARMIL1 PAPPA ZFHX3	3.28e-05	192	207	7	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FRMPD4 MCAM NDUFA4L2 DGKH TAGLN COL12A1 PAPPA	3.28e-05	192	207	7	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADCY5 PDZRN4 COL6A3 FAT4 MXRA5 COL12A1 PAPPA	3.39e-05	193	207	7	cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCAM NDUFA4L2 NRXN1 TAGLN PDLIM4 ZFHX3 TNS1	3.39e-05	193	207	7	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADCY5 PDZRN4 COL6A3 FAT4 MXRA5 COL12A1 PAPPA	3.39e-05	193	207	7	6ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	NCAM2 TPRG1 COL6A3 COL12A1 CARMIL1 PAPPA ZFHX3	3.39e-05	193	207	7	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADCY5 PDZRN4 COL6A3 FAT4 MXRA5 COL12A1 PAPPA	3.39e-05	193	207	7	e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	NCAM2 FMNL2 PDZRN4 COL6A3 CARMIL1 PAPPA ZFHX3	3.51e-05	194	207	7	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	NCAM2 PDZRN4 COL6A3 COL12A1 CARMIL1 PAPPA ZFHX3	3.51e-05	194	207	7	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MCAM NDUFA4L2 ADCY5 TAGLN COL6A3 MXRA5 COL12A1	3.51e-05	194	207	7	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZGRF1 NDST3 TAGLN MMS22L WNT5A RFC2 CENPI	3.51e-05	194	207	7	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 ZNF440 ERICH3 RSPH4A COL28A1 SYNE1 MUC16	3.51e-05	194	207	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	NCAM2 FMNL2 PTBP3 COL6A3 CARMIL1 PAPPA ZFHX3	3.62e-05	195	207	7	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	P15-Mesenchymal-myocytic_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY5 OTULINL TAGLN COL6A3 COL12A1 WNT5A PDLIM4	3.74e-05	196	207	7	41ae5b0d81ad09a6663335d899b4a1e4976c3b62
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A	HGF CYP26A1 ACTA1 NDUFA4L2 HEPH NF1 SRGAP3 PKP2 MXRA5 DDX60 LMO7	1.93e-06	199	204	11	3614_UP
Disease	severe acute respiratory syndrome, COVID-19	FRMPD4 NCAM2 NRXN1 SRGAP3 PRKAG2 COL6A3 MXRA5 SGTB GRK4 DTD2 ZFHX3 CHSY3	5.66e-05	447	199	12	EFO_0000694, MONDO_0100096
Disease	Arrhythmogenic Right Ventricular Dysplasia	SCN5A PKP2	1.35e-04	3	199	2	C0349788
Disease	intellectual disability (implicated_via_orthology)	NDST4 NDST3 PLP1 NDST1 RBL1	1.56e-04	75	199	5	DOID:1059 (implicated_via_orthology)
Disease	Intellectual Disability	FRMPD4 KDM3B NF1 AP1B1 NRXN1 SRGAP3 NDST1 SYNE1 MED13L ZBTB11 HTT	2.45e-04	447	199	11	C3714756
Disease	Cardiomyopathies	HGF ADCY5 GLA SCN5A PKP2 PRKAG2	2.60e-04	130	199	6	C0878544
Disease	Ullrich congenital muscular dystrophy	COL6A3 COL12A1	2.69e-04	4	199	2	cv:C4551860
Disease	Bethlem myopathy	COL6A3 COL12A1	2.69e-04	4	199	2	cv:C1834674
Disease	BETHLEM MYOPATHY 1	COL6A3 COL12A1	2.69e-04	4	199	2	C1834674
Disease	Ullrich congenital muscular dystrophy 1	COL6A3 COL12A1	2.69e-04	4	199	2	C0410179
Disease	Bethlem myopathy (is_implicated_in)	COL6A3 COL12A1	2.69e-04	4	199	2	DOID:0050663 (is_implicated_in)
Disease	Ullrich congenital muscular dystrophy (is_implicated_in)	COL6A3 COL12A1	2.69e-04	4	199	2	DOID:0050558 (is_implicated_in)
Disease	Gastrointestinal Stromal Sarcoma	DYRK2 NDST1 CTNNA1 ZBTB11	2.85e-04	47	199	4	C3179349
Disease	Gastrointestinal Stromal Tumors	DYRK2 NDST1 CTNNA1 ZBTB11	3.63e-04	50	199	4	C0238198
Disease	Ischemic stroke	DCHS2 PICALM EML5 FGB ASTN2 PDZRN4 ABCC1 COL6A3 ZFHX3	3.77e-04	324	199	9	HP_0002140
Disease	SYSTEMIC LUPUS ERYTHEMATOSUS 16	C4A PRKCD	4.47e-04	5	199	2	C3280742
Disease	Squamous cell carcinoma of esophagus	FAT2 TAGLN FAT4 FAT3 SALL4	4.70e-04	95	199	5	C0279626
Disease	Brugada Syndrome (disorder)	SCN5A PKP2 AKAP9	5.51e-04	24	199	3	C1142166
Disease	autism spectrum disorder (implicated_via_orthology)	NDST4 NDST3 NRXN1 PKP2 NDST1 CTNND2	5.98e-04	152	199	6	DOID:0060041 (implicated_via_orthology)
Disease	axial length measurement, refractive error	ASTN2 RASGRF2	6.67e-04	6	199	2	EFO_0005318, MONDO_0004892
Disease	carbamazepine metabolite measurement	PICALM GRIK5	6.67e-04	6	199	2	EFO_0009891
Disease	Congenital myopathy with fiber type disproportion	ACTA1 RYR1	6.67e-04	6	199	2	cv:C0546264
Disease	rhegmatogenous retinal detachment	GFUS FAT3	6.67e-04	6	199	2	EFO_0005240
Disease	azoospermia (implicated_via_orthology)	NDST4 NDST3 NDST1	7.84e-04	27	199	3	DOID:14227 (implicated_via_orthology)
Disease	Malignant mesothelioma	HGF MCAM HEPH MLANA COL12A1	8.79e-04	109	199	5	C0345967
Disease	polycystic liver disease (implicated_via_orthology)	PKD1 HDAC6	9.29e-04	7	199	2	DOID:0050770 (implicated_via_orthology)
Disease	Headache	HGF ASTN2 FXN CHSY3	9.30e-04	64	199	4	HP_0002315
Disease	visual epilepsy (implicated_via_orthology)	KDM3B PLP1 GRIK5	1.55e-03	34	199	3	DOID:11832 (implicated_via_orthology)
Disease	glycogen storage disease (is_implicated_in)	PHKA1 PRKAG2	1.58e-03	9	199	2	DOID:2747 (is_implicated_in)
Disease	gestational age, parental genotype effect measurement	HGF ADCY5 RAP2C	1.69e-03	35	199	3	EFO_0005112, EFO_0005939
Disease	Short Stature, CTCAE	KDM3B RSPH4A	1.97e-03	10	199	2	C2919142
Disease	Short stature	KDM3B RSPH4A	1.97e-03	10	199	2	C0349588
Disease	Kunitz-type protease inhibitor 2 measurement	RYR1 YIF1B	1.97e-03	10	199	2	EFO_0008200
Disease	Peritoneal Neoplasms	MCAM MLANA	1.97e-03	10	199	2	C0031149
Disease	Carcinomatosis of peritoneal cavity	MCAM MLANA	1.97e-03	10	199	2	C0346990
Disease	diffuse plaque measurement	DCHS2 NCAM2 DNAH14 NDST3 PKP2 HSP90AA4P COL6A3 SHB SALL4 GRIK5 PIERCE1 CHSY3 TNS1	2.01e-03	758	199	13	EFO_0010699
Disease	Congenital long QT syndrome	SCN5A AKAP9	2.39e-03	11	199	2	cv:C1141890
Disease	interleukin-6 measurement, response to stimulus	CARMIL1 MUC16	2.39e-03	11	199	2	EFO_0004810, GO_0050896
Disease	Profound Mental Retardation	NF1 NRXN1 SRGAP3 NDST1 MED13L	2.57e-03	139	199	5	C0020796
Disease	Mental Retardation, Psychosocial	NF1 NRXN1 SRGAP3 NDST1 MED13L	2.57e-03	139	199	5	C0025363
Disease	Mental deficiency	NF1 NRXN1 SRGAP3 NDST1 MED13L	2.57e-03	139	199	5	C0917816
Disease	diabetes mellitus (is_marker_for)	HGF SERPINA7 APOB	2.67e-03	41	199	3	DOID:9351 (is_marker_for)
Disease	hippocampal CA4 volume	ASTN2 PDZRN4 DPP4	2.67e-03	41	199	3	EFO_0009396
Disease	rotator cuff tear, shoulder impingement syndrome	FRMPD4 ASTN2	2.86e-03	12	199	2	EFO_1001178, EFO_1001250
Disease	pulmonary function measurement, forced expiratory volume, smoking behaviour measurement	ASTN2 TNS1	2.86e-03	12	199	2	EFO_0003892, EFO_0004314, EFO_0005671
Disease	Long QT syndrome	SCN5A AKAP9	2.86e-03	12	199	2	cv:C0023976
Disease	hemorrhoid	NF1 AP1B1 ASTN2 LMO7 PAPPA	3.27e-03	147	199	5	EFO_0009552
Disease	Autosomal Dominant Myotubular Myopathy	ACTA1 RYR1	3.36e-03	13	199	2	C3661489
Disease	Centronuclear myopathy	ACTA1 RYR1	3.36e-03	13	199	2	C0175709
Disease	kynurenic acid measurement	DYRK2 BUB3	3.36e-03	13	199	2	EFO_0010506
Disease	X-linked centronuclear myopathy	ACTA1 RYR1	3.36e-03	13	199	2	C0410203
Disease	Myopathy, Centronuclear, 1	ACTA1 RYR1	3.36e-03	13	199	2	C4551952
Disease	Brugada Syndrome 1	SCN5A PKP2	3.36e-03	13	199	2	C4551804
Disease	response to ketamine, dissociation measurement	HSP90AA4P RASGRF2	3.36e-03	13	199	2	EFO_0009748, EFO_0009750
Disease	Congenital Structural Myopathy	ACTA1 RYR1	3.36e-03	13	199	2	C0752282
Disease	urate measurement, bone density	LINC00587 DNAH14 TPRG1 TTC28 PPFIBP1 SYNE1 SGTA CARMIL1 HSD17B12 CTNNA1 CTNND2	3.36e-03	619	199	11	EFO_0003923, EFO_0004531
Disease	obesity (implicated_via_orthology)	DCHS2 FAT4 HDAC6 MED13L HSD17B12 ZFHX3	3.49e-03	215	199	6	DOID:9970 (implicated_via_orthology)
Disease	eye morphology measurement	PHKA1 ASTN2 CSTPP1 WNT5A FXN PAPPA	3.73e-03	218	199	6	EFO_0007858
Disease	Myopathy, Centronuclear, Autosomal Dominant	ACTA1 RYR1	3.90e-03	14	199	2	C1834558
Disease	Tubular Aggregate Myopathy	ACTA1 RYR1	3.90e-03	14	199	2	C0410207
Disease	Left ventricular noncompaction	MIB1 PKP2	3.90e-03	14	199	2	C1960469
Disease	polycystic kidney disease (implicated_via_orthology)	PKD1 HDAC6	3.90e-03	14	199	2	DOID:0080322 (implicated_via_orthology)
Disease	Cardiomyopathy	SCN5A PKP2 PRKAG2	3.94e-03	47	199	3	cv:C0878544
Disease	Cardiomyopathy, Dilated	ACTA1 SCN5A PKP2	4.18e-03	48	199	3	C0007193
Disease	hippocampal CA1 volume	ASTN2 DPP4 PAPPA	4.18e-03	48	199	3	EFO_0009394
Disease	unipolar depression, bipolar disorder	ITIH3 ASTN2 FAT4 SYNE1 GRIK5	4.21e-03	156	199	5	EFO_0003761, MONDO_0004985
Disease	hepatoblastoma (is_marker_for)	SALL4 ZFHX3	4.49e-03	15	199	2	DOID:687 (is_marker_for)
Disease	Autosomal Recessive Centronuclear Myopathy	ACTA1 RYR1	4.49e-03	15	199	2	C3645536
Disease	anemia (implicated_via_orthology)	ALAD SLC4A9	4.49e-03	15	199	2	DOID:2355 (implicated_via_orthology)
Disease	Tourette syndrome	LINC00587 PICALM MUC16	4.69e-03	50	199	3	EFO_0004895
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	TSNAXIP1 CYP26A1 TNFRSF10B ITIH3 APOB CSNK1G3	4.73e-03	229	199	6	EFO_0004639, EFO_0008317
Disease	lymphocyte count	FMNL2 ADCY5 ABCG4 KLHL14 RANBP10 ABCC1 MMS22L TTC28 PCDHGB5 RBL1 GRIK5 MED13L CLSTN1 SBNO2 ZNF710 PDLIM4 PAPPA ACAP2 HTT	4.95e-03	1464	199	19	EFO_0004587
Disease	Barrett Epithelium	HGF CYP26A1	5.10e-03	16	199	2	C1258085
Disease	Romano-Ward Syndrome	SCN5A AKAP9	5.10e-03	16	199	2	C0035828
Disease	sickle cell anemia (is_implicated_in)	ALAD APOB	5.10e-03	16	199	2	DOID:10923 (is_implicated_in)
Disease	Barrett Esophagus	HGF CYP26A1	5.10e-03	16	199	2	C0004763
Disease	chronic kidney disease	ADCY5 NDST3 SCG2 PRKAG2 COL6A3 GTF2A1	5.36e-03	235	199	6	EFO_0003884
Disease	response to cisplatin, platinum measurement	NRXN1 SARDH MMS22L	5.52e-03	53	199	3	EFO_0010154, GO_0072718
Disease	apolipoprotein B measurement	DCHS2 CYP26A1 NF1 PMPCA FGB NKPD1 TAGLN APOB CSNK1G3 ZFHX3 HTT	5.59e-03	663	199	11	EFO_0004615
Disease	Glycogen storage disease	PHKA1 SLC37A4	5.76e-03	17	199	2	cv:C0017919
Disease	muscular dystrophy (is_implicated_in)	COL6A3 SYNE1	5.76e-03	17	199	2	DOID:9884 (is_implicated_in)
Disease	Moyamoya Disease	NF1 GLA	5.76e-03	17	199	2	C0026654
Disease	body fat percentage	ADCY5 NRXN1 SRGAP3 PDZRN4 MMS22L HSD17B12 ZFHX3 SLC37A4 HTT	6.12e-03	488	199	9	EFO_0007800
Disease	Premature atrial contractions	ZNF440 SCN5A ZNF69	6.13e-03	55	199	3	HP_0006699
Disease	pulse pressure measurement	ADCY5 ITIH3 PKD1 PRKAG2 COL6A3 MXRA5 TTC28 FAT3 CARMIL1 SHB CELA2B INO80 MED13L SLC5A11 FMNL3 CSNK1G3 ZFHX3 CTNND2	6.41e-03	1392	199	18	EFO_0005763
Disease	Congenital Fiber Type Disproportion	ACTA1 RYR1	6.45e-03	18	199	2	C0546264
Disease	Leukemia, Myelocytic, Acute	HGF PICALM NF1 CTNNA1 SLX4	6.49e-03	173	199	5	C0023467
Disease	Alzheimer disease, polygenic risk score	DNAJA2 PICALM DNAH14 NRXN1 SLC4A9 CSTPP1 MMS22L NCKIPSD CHSY3 CTNNA1	6.70e-03	586	199	10	EFO_0030082, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
HELGLAFTKNRMNYT	TNFSF15	121	O95150
QRKGESDGAYIHRMQ	CCDC137	116	Q6PK04
LMDKHLAGYFNNTRI	ERICH3	16	Q5RHP9
AGKSTFMNILAGYRE	ABCG4	106	Q9H172
MKQNLDELGIGTYHN	PRKAG2	421	Q9UGJ0
LNRMEYRLQKGAGFH	SLC4A9	741	Q96Q91
RHKGEMENALRSYSN	AKAP9	466	Q99996
RKGSLRYAKGQSQTM	CNPY4	106	Q8N129
IMKKRNGGGSLNNYS	AGAP9	246	Q5VTM2
KGYMRIQQFRKADGS	C4B	1051	P0C0L5
IRKDLYANNVMSGGT	ACTA1	291	P68133
YRTGQHSNKFMLVLA	ATAD3A	486	Q9NVI7
GKGRLDYHMSQNEKR	FAT4	4211	Q6V0I7
NEMHVGSLLNGRKYS	ARID2	1286	Q68CP9
KMSSIHERRNSGYQG	BIVM	481	Q86UB2
ANSMRLKYQHTGAVL	BUB3	46	O43684
ADGYKHMSLALNRTG	GLA	181	P06280
EGQDMLYQSLKLTNG	AP1B1	891	Q10567
GELDKAMQHISYLNS	CLSTN1	596	O94985
GIVMEGYLFKRASNA	ACAP2	266	Q15057
YNHLGGNQVSKEMKR	ADCY5	681	O95622
DVDGSGNYLMLTHKQ	DHX32	631	Q7L7V1
TMHLGLKSTGNYVDF	CTNND2	1186	Q9UQB3
DTLFGEMLHGYNNRT	ASTN2	771	O75129
GFSLHYQKARGMDNV	IGDCC4	461	Q8TDY8
IFMTHLSNYGNDRLG	NDST3	516	O95803
GREYGKNLAHTEMLQ	RANBP10	526	Q6VN20
LGDMNVGKTSLLQRY	RAB20	11	Q9NX57
SMRDLYIKNGQGFIL	RAP2A	66	P10114
GFRNYNTSIDMQRGK	PDZRN4	706	Q6ZMN7
SMRDLYIKNGQGFIL	RAP2B	66	P61225
SMRDLYIKNGQGFIL	RAP2C	66	Q9Y3L5
GMLNTYSLNGVLQSE	INO80	91	Q9ULG1
SINSGNGKLYALRTM	PCDHB1	506	Q9Y5F3
VNSPHRQYKGMFDTL	SLC25A32	156	Q9H2D1
IRFLKGMGYSTHAAQ	NUB1	436	Q9Y5A7
QSVYLMNLRKSGTLG	FXN	71	Q16595
NLQYGEDMRHPGSRK	MUC16	13021	Q8WXI7
FLTKNNLKYMARGGL	PAN2	131	Q504Q3
GGMFRNNTLNVYLEK	PIERCE1	91	Q5BN46
NRGNAGVKRSAAEMY	HNRNPCL1	91	O60812
GGRLKGRNMQYHSNS	DTD2	96	Q96FN9
QGYRLDKEGNSMSRH	LILRA4	56	P59901
TLSYGMFENKRNAVH	LFNG	331	Q8NES3
AIMNRKLGYNSGLFL	MED13L	1166	Q71F56
RNGYRALMDKSLHVG	MLANA	51	Q16655
NRGNAGVKRSAAEMY	HNRNPCL2	91	B2RXH8
SLMNKEESYGGRDQH	GRXCR2	156	A6NFK2
YTLQKGQRRAGMATE	TRMU	391	O75648
NGGDLMYHIQDKGRF	PRKCD	431	Q05655
LMEQGLGSYLNSGKH	PPFIBP1	656	Q86W92
EIGHLTGLQKFYMAS	LRRIQ4	206	A6NIV6
GLGNRVSVMSYSAKF	ALAD	186	P13716
QREAYSKLLSHLGQM	MMS22L	1216	Q6ZRQ5
FNTTMGKLQRQLYKG	GARIN4	21	Q8IYT1
NRGNAGVKRSAAEMY	HNRNPCL3	91	B7ZW38
SILAALRKMQDGYFG	PHKA1	581	P46020
AHMLLNKTFGSYLGV	AQP7P3	56	A6NL99
IMFNYLDQKLGGSSG	DDX58	386	O95786
YKHGSLIGLVQDNRM	DDX60	1646	Q8IY21
QFGGMLLAYSGVQSK	MICU1	326	Q9BPX6
SVNKYRGTAGNALMD	FGB	371	P02675
YQLKIRGSNMAGAFT	FAT2	1726	Q9NYQ8
NVGMSTLYDIRAHKA	JRK	46	O75564
HSTLQMDGAQRGLAY	KCNJ13	26	O60928
FMTHLSNYGNDRLGL	NDST1	526	P52848
GTALYNIGDMVHAAR	KDM3B	1101	Q7LBC6
AYMESQGAHRAGLAK	KDM4D	36	Q6B0I6
RLFQKIYGENGSKSM	LMO7	691	Q8WWI1
RMDGSYRSVELKHGN	KRIT1	426	O00522
RGSGYQGDKIMHAIN	DPP4	581	P27487
AGKGYSHDNRTAQIM	GOLGA6L7	571	A0A1B0GV03
AMVGGLFRNIKYNLD	GFUS	71	Q13630
NRGNAGVKRSAAEMY	HNRNPCL4	91	P0DMR1
GKNYMGNLSQTRSGL	HGF	396	P14210
FMTHLSNYGNDRLGL	NDST4	516	Q9H3R1
QRNGLMLHTGKSADY	NRXN1	316	Q9ULB1
DLGLNGQVSYSIMAS	PCDHGB5	476	Q9Y5G0
KVLMLGGSALNHNYR	PAPPA	236	Q13219
MNNYFGIGLDAKISL	DGKH	771	Q86XP1
GTARYMSINTHLGKE	CSNK1G3	211	Q9Y6M4
TEFNGIRDYHKRGSM	OTULINL	211	Q9NUU6
AKNLYRVGFEGMSDL	MIB1	201	Q86YT6
IDMDSGKNGQLLYFL	DCHS2	1216	Q6V1P9
MAGASLGARFYRQIK	NDUFA4L2	1	Q9NRX3
GGFYSNRSLALVMSQ	PGBD5	191	Q8N414
QRDGNDLHMTYKIGL	DNAJA2	261	O60884
GYLSDRAMAKAGLSN	SLC37A4	281	O43826
GSAYQAMILGVDSKN	APOB	1711	P04114
ELGSMSYKLGQVSIH	HTT	2606	P42858
MNDRLYAIGGNHLKG	KLHL14	516	Q9P2G3
FKLAVDNMQYLGEGT	COL28A1	861	Q2UY09
YMGNAGRKERSDALN	CTNNA1	351	P35221
YGFLMALSKHRGINQ	CSTPP1	236	Q9H6J7
SSSGIYRVMLGQHNL	CELA2B	76	P08218
YKGGNTLTGMALNFI	COL12A1	1271	Q99715
MAASGLDHLKNGYRR	CENPC	1	Q03188
RKDMSGHYQNALYLG	COPA	726	P53621
RNLYIGSANDMKGLD	FRMPD4	686	Q14CM0
LALGNYMNSSKRGAV	FMNL3	771	Q8IVF7
NQTGKGLEYIMQSHL	COL6A3	116	P12111
GLEYIMQSHLTKAAG	COL6A3	121	P12111
LIYTIEAGNTGNMFK	FAT3	1601	Q8TDW7
NGFYMRADQSGTLLA	FSCN3	471	Q9NQT6
QSRTNGYLIHALMGS	HSD17B12	266	Q53GQ0
LALGNYMNSSKRGAV	FMNL2	826	Q96PY5
IIGNSMGLVNAYSHK	DNAH14	671	Q0VDD8
SLLGFVYKLEGNMNE	IFIT1	441	P09914
FNTSMGKLQRQLYKG	GARIN6	21	Q8NEG0
HYDMIERKLGSRNSN	GEN1	381	Q17RS7
GNVLRGDDLSHMYNF	CARMIL1	346	Q5VZK9
SGLYRGMKARNLIHA	CYP26A1	231	O43174
LQTNDGNGKRLFYRM	EML5	466	Q05BV3
KYCGLGLQMNHSIES	DCBLD2	146	Q96PD2
THANRIYRMNKLGLG	HSP90AA4P	371	Q58FG1
ILNAYGMGDRKRTNS	LINC00587	16	B1AMM8
LMQGSRGLTDQAIFY	HDAC6	1091	Q9UBN7
LGGSMNSVSKLIHYV	CENPI	526	Q92674
REMRLSNGKLYSAGA	GRIK5	881	Q16478
IMNGGDLKFHIYNLG	GRK4	266	P32298
GGLESRVLKYTAQNM	CREB3	176	O43889
QYTSMLNGGLAVKTN	SALL4	971	Q9UJQ4
LLKFLQMNGYAVTRG	RYR1	2926	P21817
IYFLGLNAKKRQGMT	DYRK2	181	Q92630
KGYMRIQQFRKADGS	C4A	1051	P0C0L4
LKMSSGQEYLFRHGD	CYP8B1	366	Q9UNU6
GTYHVQLRATNMLGS	PKD1	1691	P98161
LVNMNGYTKGARNEL	OGT	636	O15294
NYRLPSGNHMKESRE	MCAM	226	P43121
QQRGLFYSMAKDAGL	ABCC1	1516	P33527
HMYQARGLIAADSNG	FER1L6	831	Q2WGJ9
GFNLYDHLSNMLTKI	RSPH4A	226	Q5TD94
GKGMFSRLYLNVLNR	PMPCA	356	Q10713
GKGFEDLMTVNLARY	STRADA	76	Q7RTN6
GSFLEDARAYMKGQL	CARS2	371	Q9HA77
RLSSMNLGYKHYQGI	SEL1L3	606	Q68CR1
KHDYSLSLRSNQGFM	SHB	441	Q15464
SYVGRGLNSDQLSML	STAT2	506	P52630
FYSGGMINNAIASLR	SLC9B1P1	41	A6NJY1
AYGRMGLALSSLNKH	SGTA	161	O43765
KMYHSLAGSLQDSGI	SYNE1	4816	Q8NF91
MGRTLANKHGYDVDS	SLC26A9	351	Q7LBE3
MKGTADNGYLFLNRT	NKPD1	286	Q17RQ9
GNFRMIGDDLVNSYH	RBL1	186	P28749
MQKSVRYNEGHALYL	RASGRF2	1	O14827
LNATNYFGRIVDKHM	TDRD12	891	Q587J7
RKTYFGKLGIANAQM	ITIH3	706	Q06033
FSEYHEKRMLVSGQG	HDHD5	126	Q9BXW7
AINGKLYANLRGLTM	HEPH	966	Q9BQS7
KQSGSFRYLQGMLEA	PDLIM4	206	P50479
NYATLKGHSGAVMEL	SNRNP40	101	Q96DI7
HPDLFQNRMLSKSGY	SCG2	401	P13521
VGMQLFGKNYSELRD	SCN5A	856	Q14524
NLSHAKGGALMAAYL	SLC5A11	301	Q8WWX8
KVSGMYIARQLSFSG	SBNO2	471	Q9Y2G9
MALGSLAVTKNDGHY	TAGLN	131	Q01995
NTAMRDGGKYSLEQR	NCKIPSD	76	Q9NZQ3
ERMGVTYGAQAHLKS	SARDH	891	Q9UL12
MKLSVNEAQLGFYLG	SLX4	1	Q8IY92
LNFYKQTMDLLTGSG	STRA8	151	Q7Z7C7
AGDNIITAQAMYKGL	CLDN7	36	O95471
GVMTAQKYLGSRALA	CHSY3	176	Q70JA7
LSNFLDKSGLQGYDM	PICALM	106	Q13492
GIMNLNGRDYIFSKA	GTF2A1	356	P52655
SSILSMYQAARAGGQ	PEX11G	221	Q96HA9
FNMNIRGDIGHKAYE	ZNF440	121	Q8IYI8
ISANGSNLYDAVRMG	TMF1	966	P82094
AMAYGSSLAAQGKEL	YIF1B	81	Q5BJH7
AKRHNLAIDLMYGGI	USP22	96	Q9UPT9
SVNEGAYIRLHKGME	ZBTB11	511	O95625
STKLVSGFLMGQRYH	ZNF671	271	Q8TAW3
QREIMGLTKHGLEYS	ZNF383	101	Q8NA42
GNKDSIYSLAMNQLG	WDR48	166	Q8TAF3
GSGTQYHMQLAKQLA	VPS36	236	Q86VN1
EAASRIGGHQKSMYL	NCAM2	381	O15394
KRRMATFGSAGSINY	SRGAP3	911	O43295
MEDFLLSNGYQLGKT	TSSK3	1	Q96PN8
AVSLQGKLYMANAGD	PPM1M	221	Q96MI6
GKLYMANAGDSRAIL	PPM1M	226	Q96MI6
LVNQHSILMGEGSYK	ZNF514	166	Q96K75
VHYFSGLLSGSIKMN	TNS1	166	Q9HBL0
LGATLLKMGIQHAYS	SERPINA7	316	P05543
YTGLMSFIGNRNKLG	TPRG1	251	Q6ZUI0
TMAAFGLKYLLNDTG	VN1R1	106	Q9GZP7
VCGKSFNRMYNLLGH	ZNF710	551	Q8N1W2
DYSSNILSLGKMNGL	TTC41P	1221	Q6P2S7
GLGYHKDLQTRATFM	NF1	1166	P21359
RHLYFALKESQNGMQ	ROS1	1236	P08922
HAKGSYESARILMNL	WNT5A	206	P41221
GYTHMKIAEGVNSLL	RFC2	321	P35250
HLLSSGKFMYLEGNA	TNFRSF10B	421	O14763
YEHNNRKMSGLIVGS	GTF3C4	321	Q9UKN8
GTYMATSGLDHQLKI	WDR46	371	O15213
AMNHLSGQRLYGKVL	PTBP3	411	O95758
GYLLSGFTVAMDNLK	TRMT6	451	Q9UJA5
ASSNLGIIHQMKGDY	TTC28	476	Q96AY4
IANDLFYKGALMNGV	ZGRF1	1886	Q86YA3
FNMNIRGDIGHKAYE	ZNF69	141	Q9UC07
YGRMGLALTALNKFE	SGTB	156	Q96EQ0
NMTFSNGKLRVKGIY	UNQ5830/PRO19650/PRO19816	41	Q6UY13
GAHMNVGRTYKNLNR	TMTC3	481	Q6ZXV5
RQGQSSHYGQMDRKG	RPTN	336	Q6XPR3
SSIKNAYEGMLAHQR	TSNAXIP1	96	Q2TAA8
FNMNIRGDIGHKAYE	ZNF763	121	Q0D2J5
MASAGTQHYSIGLRQ	TTLL4	1	Q14679
SMGNLLEKENYLTAG	PKP2	251	Q99959
HEAKRAGYNLTLSAM	ZFHX3	2736	Q15911
MKDIGQQLYTTHLNG	ZNF518B	1	Q9C0D4
GQRHMDLLTGYSKLI	nan	16	Q9UFV3
HGGKMFVYLENGQSL	ZNF554	291	Q86TJ5
LYNLGGSRSISINLM	KRT77	61	Q7Z794
SGQQLQRFYHKADGM	MXRA5	2586	Q9NR99
ATYNFAVLKLMGRGT	PLP1	261	P60201