Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin receptor activity	INSR INSRR	3.32e-05	3	67	2	GO:0005009
GeneOntologyMolecularFunction	myosin binding	PYCARD ACTA1 ACTC1 TRAK1	1.91e-04	85	67	4	GO:0017022
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1 ACTG2	4.48e-10	5	65	4	GO:0090131
GeneOntologyBiologicalProcess	mesenchyme morphogenesis	ACTA1 ACTA2 ACTC1 ACTG2 ROBO2	1.90e-06	65	65	5	GO:0072132
GeneOntologyCellularComponent	transferase complex	RGPD4 DCAF4L2 RPAP1 PIK3R6 KLHL7 PYCARD POLR2B RGPD3 INSR INSRR SOCS1 ZSWIM4	3.59e-05	963	65	12	GO:1990234
GeneOntologyCellularComponent	filopodium	FARP1 ACTA1 ACTA2 ACTC1 ACTG2	4.05e-05	123	65	5	GO:0030175
GeneOntologyCellularComponent	insulin receptor complex	INSR INSRR	5.69e-05	4	65	2	GO:0005899
GeneOntologyCellularComponent	actin cytoskeleton	ACTR1A TRIP6 ACTR10 ACTA1 ACTA2 ACTC1 ACTG2 MACF1 DAAM1	6.96e-05	576	65	9	GO:0015629
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	RPAP1 PIK3R6 PYCARD POLR2B INSR INSRR SOCS1	8.00e-05	335	65	7	GO:0061695
GeneOntologyCellularComponent	cell leading edge	ACTA1 ACTA2 INSR ACTC1 ACTG2 MACF1 ROBO2 SHISA6	1.55e-04	500	65	8	GO:0031252
GeneOntologyCellularComponent	dynactin complex	ACTR1A ACTR10	2.63e-04	8	65	2	GO:0005869
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD3	2.63e-04	8	65	2	GO:1990723
GeneOntologyCellularComponent	contractile actin filament bundle	TRIP6 ACTA1 ACTA2 DAAM1	3.46e-04	107	65	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	TRIP6 ACTA1 ACTA2 DAAM1	3.46e-04	107	65	4	GO:0001725
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD3	4.22e-04	10	65	2	GO:0044614
GeneOntologyCellularComponent	actomyosin	TRIP6 ACTA1 ACTA2 DAAM1	4.85e-04	117	65	4	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	TRIP6 ACTA1 ACTA2 DAAM1	5.01e-04	118	65	4	GO:0032432
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD3	8.46e-04	14	65	2	GO:0005642
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD3	1.41e-03	18	65	2	GO:0044615
GeneOntologyCellularComponent	actin-based cell projection	FARP1 ACTA1 ACTA2 ACTC1 ACTG2	1.73e-03	278	65	5	GO:0098858
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD3	1.74e-03	20	65	2	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RGPD3	1.92e-03	21	65	2	GO:0106068
GeneOntologyCellularComponent	neuron projection membrane	INSR ROBO2 SHISA6	2.13e-03	82	65	3	GO:0032589
GeneOntologyCellularComponent	azurophil granule lumen	DPP7 PYCARD ACTR10	2.87e-03	91	65	3	GO:0035578
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex	PIK3R6 SOCS1	3.66e-03	29	65	2	GO:0005942
GeneOntologyCellularComponent	leading edge membrane	INSR MACF1 ROBO2 SHISA6	4.15e-03	210	65	4	GO:0031256
Domain	Actin	ACTR1A ACTR10 ACTA1 ACTA2 ACTC1 ACTG2	1.16e-09	31	67	6	IPR004000
Domain	Actin	ACTR1A ACTR10 ACTA1 ACTA2 ACTC1 ACTG2	1.16e-09	31	67	6	PF00022
Domain	ACTIN	ACTR1A ACTR10 ACTA1 ACTA2 ACTC1 ACTG2	1.16e-09	31	67	6	SM00268
Domain	Actin_CS	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.16e-09	16	67	5	IPR004001
Domain	ACTINS_2	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.05e-09	17	67	5	PS00432
Domain	Actin/actin-like_CS	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.22e-09	18	67	5	IPR020902
Domain	ACTINS_ACT_LIKE	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	5.71e-09	19	67	5	PS01132
Domain	ACTINS_1	ACTA1 ACTA2 ACTC1 ACTG2	1.05e-08	8	67	4	PS00406
Domain	Tyr_kinase_insulin-like_rcpt	INSR INSRR	3.79e-05	3	67	2	IPR016246
Domain	Furin-like	INSR INSRR	2.63e-04	7	67	2	PF00757
Domain	Rcpt_L-dom	INSR INSRR	2.63e-04	7	67	2	IPR000494
Domain	GCC2_Rab_bind	RGPD4 RGPD3	2.63e-04	7	67	2	IPR032023
Domain	Furin-like_Cys-rich_dom	INSR INSRR	2.63e-04	7	67	2	IPR006211
Domain	Recep_L_domain	INSR INSRR	2.63e-04	7	67	2	PF01030
Domain	Rab_bind	RGPD4 RGPD3	2.63e-04	7	67	2	PF16704
Domain	-	INSR INSRR	2.63e-04	7	67	2	3.80.20.20
Domain	-	RGPD4 RGPD3	5.60e-04	10	67	2	1.10.220.60
Domain	Grip	RGPD4 RGPD3	6.83e-04	11	67	2	SM00755
Domain	GRIP	RGPD4 RGPD3	6.83e-04	11	67	2	PF01465
Domain	Tyr_kinase_rcpt_2_CS	INSR INSRR	6.83e-04	11	67	2	IPR002011
Domain	Ran_BP1	RGPD4 RGPD3	8.18e-04	12	67	2	PF00638
Domain	GRIP_dom	RGPD4 RGPD3	8.18e-04	12	67	2	IPR000237
Domain	RECEPTOR_TYR_KIN_II	INSR INSRR	8.18e-04	12	67	2	PS00239
Domain	GRIP	RGPD4 RGPD3	8.18e-04	12	67	2	PS50913
Domain	RANBD1	RGPD4 RGPD3	8.18e-04	12	67	2	PS50196
Domain	RanBD	RGPD4 RGPD3	9.64e-04	13	67	2	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD3	9.64e-04	13	67	2	IPR000156
Domain	-	CSE1L MROH1 RIPOR3 DAAM1 CTNND2	1.20e-03	222	67	5	1.25.10.10
Domain	Furin_repeat	INSR INSRR	1.87e-03	18	67	2	IPR006212
Domain	FU	INSR INSRR	1.87e-03	18	67	2	SM00261
Domain	ARM-like	CSE1L MROH1 RIPOR3 DAAM1 CTNND2	2.83e-03	270	67	5	IPR011989
Domain	TyrKc	INSR INSRR MAP3K21	3.90e-03	88	67	3	SM00219
Domain	Tyr_kinase_cat_dom	INSR INSRR MAP3K21	3.90e-03	88	67	3	IPR020635
Domain	FERM_C	FARP1 FRMD1	4.20e-03	27	67	2	SM01196
Domain	FERM_PH-like_C	FARP1 FRMD1	4.20e-03	27	67	2	IPR018980
Domain	FERM_N	FARP1 FRMD1	6.23e-03	33	67	2	PF09379
Domain	FERM_N	FARP1 FRMD1	6.23e-03	33	67	2	IPR018979
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	ACTA1 ACTA2 ACTC1 ACTG2	1.74e-05	47	47	4	M39829
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	11709093
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	9971772
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	12009869
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	23017337
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	10074138
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTC1 ACTG2	2.00e-10	6	68	4	9841925
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTC1 ACTG2	4.66e-10	7	68	4	17504171
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTC1 ACTG2	4.66e-10	7	68	4	22535526
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTC1 ACTG2	4.66e-10	7	68	4	22465675
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTC1 ACTG2	4.66e-10	7	68	4	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTC1 ACTG2	4.66e-10	7	68	4	22640593
Pubmed	Essential and supporting host cell factors for HIV-1 budding.	ACTA1 ACTA2 ACTC1 ACTG2 SOCS1	8.05e-10	23	68	5	22004035
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTC1 ACTG2	9.30e-10	8	68	4	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTC1 ACTG2	9.30e-10	8	68	4	20147394
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTC1 ACTG2	9.30e-10	8	68	4	23260110
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTC1 ACTG2	1.67e-09	9	68	4	8892894
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTC1 ACTG2	1.67e-09	9	68	4	10556093
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTC1 ACTG2	1.67e-09	9	68	4	18775311
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTC1 ACTG2	2.78e-09	10	68	4	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTC1 ACTG2	2.78e-09	10	68	4	23575248
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTC1 ACTG2	2.78e-09	10	68	4	1907279
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTC1 ACTG2	4.36e-09	11	68	4	30962377
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTC1 ACTG2	4.36e-09	11	68	4	23294842
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTC1 ACTG2	4.36e-09	11	68	4	19639585
Pubmed	The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.	TCF15 ACTA1 ACTA2 ACTC1 ACTG2	4.75e-09	32	68	5	23369715
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTC1 ACTG2	6.54e-09	12	68	4	23071112
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	7.15e-09	3	68	3	7780165
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	ACTA1 ACTA2 ACTC1 ACTG2	1.32e-08	14	68	4	21923909
Pubmed	Regulating the functions of the HIV-1 matrix protein.	ACTA1 ACTA2 ACTC1 ACTG2	1.32e-08	14	68	4	17411366
Pubmed	Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.	ACTA1 ACTA2 ACTC1 ACTG2	3.12e-08	17	68	4	17360745
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	ACTA1 ACTA2 ACTC1 ACTG2	3.12e-08	17	68	4	8997639
Pubmed	Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.	ACTA1 ACTA2 ACTC1 ACTG2	9.52e-08	22	68	4	16526095
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	ACTA1 ACTA2 ACTC1 ACTG2	1.93e-07	26	68	4	24742657
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	2.49e-07	7	68	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	2.49e-07	7	68	3	30289203
Pubmed	Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.	ACTR1A ACTR10 ACTA1	2.49e-07	7	68	3	12857853
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	3.98e-07	8	68	3	20096780
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	5.95e-07	9	68	3	12297046
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	RGPD4 TDRD5 CSE1L RGPD3 ACTA1 ACTA2 ACTC1 ACTG2 MACF1 CTNND2 LDHA	7.01e-07	844	68	11	25963833
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	8.49e-07	10	68	3	21749862
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1	1.17e-06	11	68	3	22207710
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	1.55e-06	12	68	3	31042497
Pubmed	Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.	ACTA1 ACTA2 ACTC1	2.02e-06	13	68	3	18400219
Pubmed	Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.	ACTA1 ACTA2 ACTC1	3.20e-06	15	68	3	24598388
Pubmed	Characterization of a hybrid receptor formed by dimerization of the insulin receptor-related receptor (IRR) with the insulin receptor (IR): coexpression of cDNAs encoding human IRR and human IR in NIH-3T3 cells.	INSR INSRR	3.77e-06	2	68	2	8916919
Pubmed	Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.	ACTA1 ACTC1	3.77e-06	2	68	2	19468071
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	3.77e-06	2	68	2	20706863
Pubmed	Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.	ACTA1 MACF1	3.77e-06	2	68	2	10559237
Pubmed	alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.	ACTA1 ACTC1	3.77e-06	2	68	2	1893870
Pubmed	Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor.	INSR INSRR	3.77e-06	2	68	2	11463843
Pubmed	Microtubule actin cross-linking factor (MACF): a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons.	ACTA1 MACF1	3.77e-06	2	68	2	10601340
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	3.77e-06	2	68	2	3023046
Pubmed	Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.	ACTA2 ACTC1	3.77e-06	2	68	2	10686609
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	3.77e-06	2	68	2	3075543
Pubmed	Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin.	ACTC1 ACTG2	3.77e-06	2	68	2	9114002
Pubmed	A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.	ACTA1 ACTC1	3.77e-06	2	68	2	2731651
Pubmed	A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.	ACTA1 ACTC1	3.77e-06	2	68	2	6897014
Pubmed	Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.	ACTA1 ACTA2 ACTC1	3.93e-06	16	68	3	16638982
Pubmed	Serum response factor is essential for mesoderm formation during mouse embryogenesis.	ACTA1 ACTA2 ACTC1	3.93e-06	16	68	3	9799237
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ACTR1A ZNF346 FBLL1 DSG2 TRIP6 DROSHA FARP1 POLR2B RGPD3 INTS15 MACF1 DAAM1 CTNND2	5.69e-06	1497	68	13	31527615
Pubmed	A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.	ACTA1 ACTA2 ACTC1	5.71e-06	18	68	3	24840128
Pubmed	Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.	ACTA1 ACTA2 ACTC1	5.71e-06	18	68	3	15929941
Pubmed	Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.	ACTA1 ACTA2 ACTC1	6.77e-06	19	68	3	30700554
Pubmed	Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.	ACTA1 ACTA2 ACTC1	6.77e-06	19	68	3	18316483
Pubmed	Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells.	POLR2B ACTA1 ACTA2 ACTC1 ACTG2 LDHA	9.15e-06	247	68	6	30713523
Pubmed	Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.	ACTA1 ACTA2 ACTC1	9.27e-06	21	68	3	20230754
Pubmed	Myocardial Mycn is essential for mouse ventricular wall morphogenesis.	ACTA1 ACTA2 ACTC1	9.27e-06	21	68	3	23063798
Pubmed	Insulin receptor-related receptor as an extracellular alkali sensor.	INSR INSRR	1.13e-05	3	68	2	21641549
Pubmed	Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT.	ACTA1 ACTC1	1.13e-05	3	68	2	22647617
Pubmed	Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance.	INSR SOCS1	1.13e-05	3	68	2	11342531
Pubmed	Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.	ACTA1 ACTC1	1.13e-05	3	68	2	22855565
Pubmed	Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.	ACTA1 ACTC1	1.13e-05	3	68	2	1728592
Pubmed	Molecular analysis of smooth muscle development in the mouse.	ACTA2 ACTG2	1.13e-05	3	68	2	8573719
Pubmed	Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.	ACTA1 ACTA2	1.13e-05	3	68	2	12119014
Pubmed	Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.	ACTA1 ACTC1	1.13e-05	3	68	2	14507647
Pubmed	Actin-DBP: the perfect structural fit?	ACTA1 ACTC1	1.13e-05	3	68	2	12554937
Pubmed	Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.	INSR INSRR	1.13e-05	3	68	2	21681845
Pubmed	The human beta-actin multigene family.	ACTA1 ACTA2	1.13e-05	3	68	2	3842206
Pubmed	Morphology of the developing muscularis externa in the mouse esophagus.	ACTA1 ACTA2	1.13e-05	3	68	2	21595780
Pubmed	The role of different Scinderin domains in the control of F-actin cytoskeleton during exocytosis.	ACTA1 ACTC1	1.13e-05	3	68	2	12438125
Pubmed	Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.	ACTA1 ACTC1	1.13e-05	3	68	2	3084797
Pubmed	The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.	ACTA1 ACTC1	1.13e-05	3	68	2	6641707
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD4 CSE1L TENM4 FARP1 RGPD3 MACF1 DAAM1 CTNND2 LDHA BIRC6 SHISA6	1.23e-05	1139	68	11	36417873
Pubmed	IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis.	PYCARD ACTA1 ACTA2	1.23e-05	23	68	3	28923684
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	ACTR1A CSE1L DSG2 FARP1 POLR2B ACTA1 LDHA	1.32e-05	399	68	7	37536630
Pubmed	Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.	ACTR1A CSE1L TRIP6 ACTA1 ACTA2 LDHA	1.55e-05	271	68	6	26816005
Pubmed	Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin.	ACTA1 ACTA2	2.25e-05	4	68	2	11812134
Pubmed	Phosphorylation of spinophilin modulates its interaction with actin filaments.	ACTA1 ACTC1	2.25e-05	4	68	2	12417592
Pubmed	Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line.	ACTA1 ACTC1	2.25e-05	4	68	2	2201580
Pubmed	Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.	INSR SOCS1	2.25e-05	4	68	2	16127460
Pubmed	Interaction between protein kinase C and actin in megakaryocyte polyploidization.	ACTA1 ACTA2	2.25e-05	4	68	2	10628374
Pubmed	Noninvasive assessment of antenatal hydronephrosis in mice reveals a critical role for Robo2 in maintaining anti-reflux mechanism.	ACTA2 ROBO2	2.25e-05	4	68	2	21949750
Interaction	POTEJ interactions	ACTA1 ACTA2 INSR ACTC1 ACTG2	7.45e-07	52	66	5	int:POTEJ
Interaction	ABRA interactions	ACTR10 ACTA1 ACTA2 ACTC1	5.71e-06	36	66	4	int:ABRA
Interaction	ACTG2 interactions	ACTA1 ACTA2 ACTC1 ACTG2	1.99e-05	49	66	4	int:ACTG2
Interaction	CLIP1 interactions	ACTR1A ACTR10 POLR2B RGPD3 LDHA BIRC6	2.99e-05	183	66	6	int:CLIP1
GeneFamily	Actins	ACTA1 ACTA2 ACTC1 ACTG2	3.76e-10	6	42	4	929
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.21e-06	26	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.65e-06	28	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_100	ACTA2 ACTC1 ACTG2	1.27e-05	15	66	3	gudmap_developingLowerUrinaryTract_P1_ureter_100_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	1.49e-05	48	66	4	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_200	ACTA1 ACTA2 ACTC1 ACTG2	1.76e-05	50	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_200_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#5_top-relative-expression-ranked_200	ACTA1 ACTC1 ACTG2	1.89e-05	17	66	3	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTG2	2.68e-05	19	66	3	gudmap_developingLowerUrinaryTract_adult_bladder_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_200	ACTA1 ACTA2 ACTC1 ACTG2	6.32e-05	69	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_J_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_200	ACTA2 ACTC1 ACTG2	7.95e-05	27	66	3	gudmap_developingLowerUrinaryTract_P1_ureter_200_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#5_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	9.71e-05	77	66	4	gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#4_top-relative-expression-ranked_200	ACTA1 ACTA2 ACTG2	1.21e-04	31	66	3	gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_200_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.30e-04	83	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_100_B
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_100	ACTA1 ACTC1 ACTG2	1.33e-04	32	66	3	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_100_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	1.49e-04	86	66	4	gudmap_developingLowerUrinaryTract_P1_ureter_500_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.49e-04	86	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_100_J
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.63e-04	88	66	4	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_1000	ACTA1 ACTA2 ACTC1 ACTG2	1.94e-04	92	66	4	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k1
CoexpressionAtlas	dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000	ACTA2 ACTC1 ACTG2	2.07e-04	37	66	3	gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_200	ACTA1 ACTA2 ACTG2	2.42e-04	39	66	3	gudmap_developingLowerUrinaryTract_adult_bladder_200_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder urothelium (LCM)_emap-30380_k-means-cluster#1_top-relative-expression-ranked_1000	DSG2 ACTA1 ACTA2 ACTG2	2.47e-04	98	66	4	gudmap_developingLowerUrinaryTract_P2_bladder urothelium (LCM)_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_100	ACTA1 ACTC1	3.38e-04	9	66	2	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_100_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	3.45e-04	107	66	4	gudmap_developingLowerUrinaryTract_adult_bladder_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#5_top-relative-expression-ranked_500	ACTA1 ACTC1 ACTG2	4.22e-04	47	66	3	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#3_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	4.54e-04	115	66	4	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	4.54e-04	115	66	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_500_k2
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA1 ACTA2 ACTC1 ACTG2 ADPRHL1 CIDEA	2.09e-07	166	68	6	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA1 ACTA2 ACTC1 ACTG2 ADPRHL1 CIDEA	2.09e-07	166	68	6	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA1 ACTA2 ACTC1 CERCAM ADPRHL1 SHISA6	2.94e-07	176	68	6	4ed73c73972334f6dc4229920205547823252fa0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLL1 ACTA1 ACTA2 ACTC1 ACTG2	6.80e-06	173	68	5	ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLL1 ACTA1 ACTA2 ACTC1 ACTG2	6.80e-06	173	68	5	b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TENM4 ACTA2 ACTC1 ACTG2 ROBO2	9.66e-06	186	68	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ACTA1 INSR ACTC1 ADPRHL1 CTNND2	1.21e-05	195	68	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	5'-GW_trimst-1.5-LargeIntestine\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 ACTA2 ACTC1 ACTG2 SOCS1	1.27e-05	197	68	5	0b2ad6a933ff1a325649cc8f139380fd158a1d42
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 ACTA2 ACTC1 ACTG2 SOCS1	1.27e-05	197	68	5	5f6fce382f273e789ffbb75b63e9b4e87519918e
ToppCell	CD8+_Memory_T_cell-CV-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ACTA2 SOCS1 CERCAM DAAM1 LDHA	1.27e-05	197	68	5	9fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCell	CV-Moderate\|CV / Virus stimulation, Condition and Cluster	ACTA2 SOCS1 CERCAM DAAM1 LDHA	1.27e-05	197	68	5	8747a57ded96175a8365f066101ce2af80c8081d
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FAM178B ACTA1 ACTA2 ACTC1 ACTG2	1.27e-05	197	68	5	470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCell	CV-Moderate-3\|CV / Virus stimulation, Condition and Cluster	ACTA2 SOCS1 CERCAM DAAM1 LDHA	1.27e-05	197	68	5	7031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 FARP1 ACTA2 ACTG2 ROBO2	1.31e-05	198	68	5	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTC1 ACTG2 ROBO2	1.31e-05	198	68	5	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBLL1 NPFF ACTA2 ACTC1 ACTG2	1.34e-05	199	68	5	8ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 ACTA2 CERCAM CTNND2	8.62e-05	152	68	4	7e686721b95c837f2b0d5116927c8ecacef055ee
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-valve_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA2 ACTG2 GPR52 ADPRHL1	8.84e-05	153	68	4	1440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADGB ACTR1A PIK3R6 PYCARD	9.30e-05	155	68	4	51f6447945389649d99dcf7603b396195c631ead
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADGB ACTR1A PIK3R6 PYCARD	9.30e-05	155	68	4	23dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	1.10e-04	162	68	4	3f264263878af630921911c2b344ac56eb1e7099
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OR10G3 ACTA1 ACTA2 ACTG2	1.13e-04	163	68	4	51dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLCXD1 FAM178B ACTA2 ACTG2	1.21e-04	166	68	4	26f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.24e-04	167	68	4	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	1.33e-04	170	68	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.33e-04	170	68	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.33e-04	170	68	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.36e-04	171	68	4	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.36e-04	171	68	4	09e653973962fb884878089d281f0947f7a285f6
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TDRD5 ROBO2 FRMD1 SHISA6	1.48e-04	175	68	4	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	1.52e-04	176	68	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.55e-04	177	68	4	c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ADPRHL1	1.55e-04	177	68	4	7ebdcedfe02da6d05bba3d625d8bd4c4ea96e4ad
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTG2 LDHA	1.58e-04	178	68	4	7975bf0a3146ee0efa4f547af5977e6bf0ba71fd
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYCARD SOCS1 GIGYF1 BIRC6	1.65e-04	180	68	4	de87503d9caac3ebc80ab8090c1a9ee5a925b2a0
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ACTA2 ACTC1 ACTG2 ROBO2	1.69e-04	181	68	4	25915e2500430a902db37d79a749ce2990b69810
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TENM4 ACTA2 ACTG2 ROBO2	1.69e-04	181	68	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	1.69e-04	181	68	4	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	FAM178B ACTA2 ACTC1 ACTG2	1.69e-04	181	68	4	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 ACTC1 ACTG2 CIDEA	1.72e-04	182	68	4	37547b36264090b49a193a8ef3a8d88e647f0b79
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 ACTC1 ACTG2 ROBO2	1.72e-04	182	68	4	728a2152c166551ac229370c0900fe2bc426ea9b
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TENM4 ACTA2 ACTG2 ROBO2	1.76e-04	183	68	4	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ACTA1 ACTA2 ACTC1 ACTG2	1.76e-04	183	68	4	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 ACTA2 ACTG2 ROBO2	1.76e-04	183	68	4	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	ACTA2 ACTG2 ROBO2 CERCAM	1.80e-04	184	68	4	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ACTA1 ACTC1 ADPRHL1 CTNND2	1.80e-04	184	68	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	1.80e-04	184	68	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	1.83e-04	185	68	4	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 ACTA2 ACTG2 ROBO2	1.83e-04	185	68	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 ACTA2 ACTG2 ROBO2	1.83e-04	185	68	4	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	SOCS1 ADPRHL1 DAAM1 LDHA	1.91e-04	187	68	4	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ACTC1 ROBO2 ADPRHL1 CTNND2	1.95e-04	188	68	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	ACTA2 ACTC1 ACTG2 CIDEA	1.95e-04	188	68	4	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 ACTA2 ACTG2 ROBO2	1.99e-04	189	68	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACTA1 ACTC1 ADPRHL1 CTNND2	2.03e-04	190	68	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	ACTA2 ACTC1 ACTG2 ROBO2	2.03e-04	190	68	4	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACTA1 ACTA2 ACTC1 ACTG2	2.07e-04	191	68	4	d35692c652977500a3c36aa26c347a072b71e441
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 ACTA2 ACTG2 ADPRHL1	2.07e-04	191	68	4	f932980baa032748857cb367a55c37dd975c693e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACTA1 ACTA2 ACTC1 ACTG2	2.07e-04	191	68	4	2a107e9096eb58b81b3da61547904d85754f6b2f
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM4 ACTA2 ACTG2 ROBO2	2.07e-04	191	68	4	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACTA1 ACTA2 ACTC1 ACTG2	2.16e-04	193	68	4	5182284dfa7c94027e94172e08f78c86b95d63f4
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ACTA1 ACTA2 ACTC1 ACTG2	2.16e-04	193	68	4	5260ac95a15cc43a19909badad0c7e3854da920d
ToppCell	E15.5-Mesenchymal-myocytic_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACTA2 ACTC1 ACTG2 ROBO2	2.16e-04	193	68	4	3316d6a39abb6a518d45b846254325fc7a8b2035
ToppCell	E15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACTA2 ACTC1 ACTG2 ROBO2	2.16e-04	193	68	4	e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ACTA1 ACTA2 ACTC1 ACTG2	2.16e-04	193	68	4	5ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.16e-04	193	68	4	f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ACTA1 ACTA2 ACTC1 ACTG2	2.16e-04	193	68	4	4f7bab0115469c855160636d168bd6e5d4e2dd2f
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ACTA2 ACTC1 ACTG2 ROBO2	2.24e-04	195	68	4	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.24e-04	195	68	4	2514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA2 ACTG2 SOCS1 CERCAM	2.24e-04	195	68	4	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	P07-Mesenchymal\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTG2 ROBO2	2.24e-04	195	68	4	859764b605866b6c3e6edd0698670ca9c0f20745
ToppCell	E17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTG2 ROBO2	2.24e-04	195	68	4	1daddd801bd4596fffbdb822fc326d5127c96004
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 DAAM1	2.24e-04	195	68	4	c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 CERCAM	2.24e-04	195	68	4	56e7cd980f8fc2dae842e6a7bd919d4b41cebbbb
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 ACTC1 ACTG2 CIDEA	2.24e-04	195	68	4	eb2003d4f15cad213d17eda8ab7479f5a0c62164
ToppCell	E17.5-Mesenchymal-myocytic_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTG2 ROBO2	2.24e-04	195	68	4	01a750d660993017af00736215cbcff2de5909c1
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 DAAM1	2.24e-04	195	68	4	43d372373367b71243c6ea958aedccde4478618f
ToppCell	tumor_Lung-Fibroblasts-Smooth_muscle_cells\|tumor_Lung / Location, Cell class and cell subclass	ACTA2 ACTC1 ACTG2 ROBO2	2.24e-04	195	68	4	ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.24e-04	195	68	4	2414b158dc7bdec43a9671544bfb7ffc5f5168fd
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 CERCAM	2.24e-04	195	68	4	a28a504c69bc4dda7de023e1b4ea4f62390b158e
ToppCell	Pericytes\|World / shred by cell class for parenchyma	ACTA1 ACTA2 ACTC1 ACTG2	2.29e-04	196	68	4	8e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell	(5)_Fibroblast-K_(Pericytes)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ACTA1 ACTA2 ACTC1 ACTG2	2.29e-04	196	68	4	e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.29e-04	196	68	4	e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.29e-04	196	68	4	f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	ACTA1 ACTA2 ACTC1 ACTG2	2.29e-04	196	68	4	541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 MACF1 ROBO2	2.29e-04	196	68	4	028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACTA1 ACTA2 ACTC1 ACTG2	2.29e-04	196	68	4	ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-myocytic\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTA2 ACTC1 ACTG2 CIDEA	2.29e-04	196	68	4	20dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACTA1 ACTA2 ACTC1 ACTG2	2.29e-04	196	68	4	70b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCell	PND07-Mesenchymal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTG2 MACF1 ROBO2	2.29e-04	196	68	4	0050c7134473fbfd7b9f0ae8d6d337713e60b57d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37\|World / Primary Cells by Cluster	CTNND2 LDHA SHISA6 CIDEA	2.33e-04	197	68	4	00d756bc0231e1b3b88430214338c1059cb11106
ToppCell	P07-Mesenchymal-myocytic_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTG2 ROBO2	2.33e-04	197	68	4	378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCell	MatrixFB\|World / shred on cell class and cell subclass (v4)	ACTA2 ACTG2 MACF1 ROBO2	2.33e-04	197	68	4	e325de44e32021a36fffb7b7e88167b46bb051c7
ToppCell	PND03-Mesenchymal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTG2 MACF1 ROBO2	2.33e-04	197	68	4	e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.33e-04	197	68	4	26475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell	P03-Mesenchymal-myocytic_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM4 ACTA2 ACTC1 ACTG2	2.33e-04	197	68	4	079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.33e-04	197	68	4	9d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCell	mLN-(2)_B_cell-(20)_B_cell_IgA_Plasma\|mLN / shred on region, Cell_type, and subtype	OR10G3 INSR KLF15 CTNND2	2.33e-04	197	68	4	a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 ROBO2	2.33e-04	197	68	4	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 ACTA2 ACTG2 ROBO2	2.33e-04	197	68	4	090a251194da3e2806989d9a522588f83f52da7f
Computational	Muscle genes.	ACTA1 ACTA2 ACTC1 ACTG2	7.23e-06	37	37	4	MODULE_512
Computational	Genes in the cancer module 387.	ACTA1 ACTA2 ACTC1 ACTG2	2.25e-05	49	37	4	MODULE_387
Computational	Genes in the cancer module 329.	ACTA1 ACTA2 ACTC1 ACTG2	2.64e-05	51	37	4	MODULE_329
Drug	Nsc687160	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.58e-09	18	67	5	CID005459290
Drug	tolytoxin	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.13e-09	19	67	5	CID006440827
Drug	m2-19	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.13e-09	19	67	5	CID000079129
Drug	AC1L9EF8	ACTR1A SQLE ACTA1 ACTA2 ACTC1 ACTG2 GBA2	3.40e-09	79	67	7	CID000443315
Drug	AC1L8NVR	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.72e-09	21	67	5	CID000384633
Drug	NSC312786	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.72e-09	21	67	5	CID000329495
Drug	plakin	ACTR1A DSG2 ACTA1 ACTA2 ACTC1 ACTG2 MACF1	4.42e-09	82	67	7	CID000018752
Drug	CID5288653	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.77e-08	28	67	5	CID005288653
Drug	azaspiracid	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.55e-08	30	67	5	CID006451158
Drug	AC1L1HS4	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.59e-08	32	67	5	CID000004267
Drug	N,N'-p-phenylenedimaleimide	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.94e-08	34	67	5	CID000076765
Drug	1,N6-ethenoadenosine 5'-diphosphate	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.94e-08	34	67	5	CID000001312
Drug	AC1NSKFN	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	6.66e-08	36	67	5	CID005311324
Drug	C3H2N2O3S	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 LDHA	8.18e-08	74	67	6	CID000448652
Drug	AC1LD8HW	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 DAAM1	8.87e-08	75	67	6	CID000644061
Drug	epsilon-ATP	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.31e-07	41	67	5	CID000162262
Drug	AC1L8FNU	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.88e-07	44	67	5	CID000425429
Drug	AC1L22RD	ACTR1A SQLE ACTA1 ACTA2 ACTC1 ACTG2	2.83e-07	91	67	6	CID000065183
Drug	NpCaM	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.94e-07	48	67	5	CID000122259
Drug	AC1Q6LQU	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.94e-07	48	67	5	CID000072380
Drug	NSC106399	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.01e-07	51	67	5	CID000002887
Drug	3-methylhistidine	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	5.88e-07	55	67	5	CID000064969
Drug	beryllium fluoride	ACTR1A FASTK ACTA1 ACTA2 ACTC1 ACTG2	5.91e-07	103	67	6	CID000024589
Drug	dihydrocytochalasin B	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.70e-07	58	67	5	CID000003064
Drug	oryzalin	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.17e-06	63	67	5	CID000029393
Drug	1tjp	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 FOXE3	1.19e-06	116	67	6	CID005459371
Drug	protocatechuic acid	DPP7 ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.38e-06	119	67	6	CID000000072
Drug	phenylarsine oxide	ACTR1A SQLE ACTA1 ACTA2 INSR INSRR ACTC1 ACTG2	1.44e-06	275	67	8	CID000004778
Drug	5-IAF	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.47e-06	66	67	5	CID000123822
Drug	AC1OAGKW	ACTR1A PLCXD1 ACTA1 ACTA2 INSR ACTC1 ACTG2	1.60e-06	193	67	7	CID006857413
Drug	AC1L1ERT	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.84e-06	69	67	5	CID000002920
Drug	AC1MNW2N	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.98e-06	70	67	5	CID003359490
Drug	caged ATP	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.98e-06	70	67	5	CID000123806
Drug	dl-Lysine	ACTR1A PYCARD ACTA1 ACTA2 INSR INSRR ACTC1 ACTG2	2.14e-06	290	67	8	CID000000866
Drug	microcystin-LR	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 LDHA	2.21e-06	129	67	6	CID000445433
Drug	AC1OAGGW	ACTR1A ACTA1 ACTA2 INSR INSRR ACTC1 ACTG2	2.23e-06	203	67	7	CID006857364
Drug	L-Carnosine	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.44e-06	73	67	5	CID000009369
Drug	AC1NRBPQ	ACTR1A DROSHA ACTA1 ACTA2 ACTC1 ACTG2	3.14e-06	137	67	6	CID005288569
Drug	SIRIUS	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.18e-06	77	67	5	CID000091750
Drug	NSC60597	ACTR1A SQLE ACTA1 ACTA2 ACTC1 ACTG2	3.56e-06	140	67	6	CID000003327
Drug	AC1NQAAM	ACTR1A PYCARD ACTA1 ACTA2 ACTC1 ACTG2	4.19e-06	144	67	6	CID005192834
Drug	NSC 523214	ACTR1A PYCARD ACTA1 ACTA2 ACTC1 ACTG2	4.72e-06	147	67	6	CID000004752
Drug	PI(3,4,5)P3	ACTR1A ACTA1 ACTA2 INSR ACTC1 ACTG2	4.91e-06	148	67	6	CID000643963
Drug	formamide	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	5.18e-06	85	67	5	CID000000713
Drug	D-myo-inositol 1,4-bisphosphate	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	5.49e-06	86	67	5	CID000000805
Drug	Formyl	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2 BIRC6	6.37e-06	238	67	7	CID000123370
Drug	CaCl2	ACTR1A DSG2 ACTA1 ACTA2 ACTC1 ACTG2	6.64e-06	156	67	6	CID000024854
Drug	AC1NRCMD	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	6.87e-06	90	67	5	CID005289074
Drug	Epi Lovastatin	ACTR1A SQLE ACTA1 ACTA2 TM7SF2 ACTC1 ACTG2 APOBR	7.05e-06	341	67	8	CID000003962
Drug	C18:1n-7	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.65e-06	92	67	5	CID000122325
Drug	cnicin	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.65e-06	92	67	5	CID000091176
Drug	mDia	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	8.07e-06	93	67	5	CID000128346
Drug	AC1L1GXW	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	8.50e-06	94	67	5	CID000003891
Drug	manidipine	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	8.95e-06	95	67	5	CID000004008
Drug	NSC3096	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.04e-05	98	67	5	CID000002832
Drug	AC1L1BDQ	ACTR1A ACTA1 ACTA2 INSR ACTC1 ACTG2	1.20e-05	173	67	6	CID000001394
Drug	sulphoxide	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.21e-05	101	67	5	CID000008442
Drug	etheno-NAD	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.39e-05	104	67	5	CID005288160
Drug	Ro-1724	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.83e-05	110	67	5	CID000005087
Drug	AC1LCVPZ	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.83e-05	110	67	5	CID000656926
Drug	foscarnet	ACTR1A POLR2B ACTA1 ACTA2 ACTC1 ACTG2	2.04e-05	190	67	6	CID000003414
Drug	HU-211	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.17e-05	114	67	5	CID000107778
Drug	blebbistatin	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.36e-05	116	67	5	CID003476986
Drug	B0683	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.46e-05	117	67	5	CID006398969
Drug	Co-protoporphyrin IX	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.57e-05	118	67	5	CID000004972
Drug	Pb m	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.57e-05	118	67	5	CID006327255
Drug	TCNB	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	2.67e-05	119	67	5	CID000008330
Drug	methenamine silver	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 DAAM1	2.80e-05	201	67	6	CID000004101
Drug	pentoxifylline	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2 LDHA	3.09e-05	304	67	7	CID000004740
Drug	nitroglycerin	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 BIRC6	3.22e-05	206	67	6	CID000004510
Drug	Isoproterenol	DPP7 ZNF346 DSG2 KLHL7 FARP1 SQLE ACTA1 ACTA2 KLF15 ACTG2 LDHA TRAK1	3.62e-05	1016	67	12	ctd:D007545
Drug	2C5P	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	3.65e-05	127	67	5	CID000447961
Drug	NSC613009	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.09e-05	130	67	5	CID000003800
Drug	AC1LADJ6	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.09e-05	130	67	5	CID000486032
Drug	pyrene	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	4.24e-05	131	67	5	CID000031423
Drug	AC1Q6M8X	ZNF346 SOCS1	5.10e-05	4	67	2	CID000119052
Drug	auxin	ACTR1A ACTA1 ACTA2 TM7SF2 ACTC1 ACTG2	5.13e-05	224	67	6	CID000000801
Drug	thalidomide	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2 FOXE3	5.80e-05	229	67	6	CID000005426
Drug	NSC-351907	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2	5.80e-05	229	67	6	CID000004016
Drug	0-to	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	6.02e-05	141	67	5	CID000002051
Drug	DE gel	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	6.43e-05	143	67	5	CID000008146
Drug	NSC529592	ACTR1A POLR2B ACTA1 ACTA2 ACTC1 ACTG2	6.54e-05	234	67	6	CID000014403
Drug	candesartan cilexetil	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	6.87e-05	145	67	5	CID000002540
Drug	dihydrosphingosine	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.10e-05	146	67	5	CID000003126
Drug	fluorescein isothiocyanate	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.33e-05	147	67	5	CID000018730
Drug	ML-9	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	7.33e-05	147	67	5	CID000004217
Drug	AC1L1KMJ	ACTR1A CSE1L ACTA1 ACTA2 ACTC1 ACTG2 MACF1 LDHA	7.62e-05	476	67	8	CID000030956
Drug	enantio-PAF-C16	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2	8.23e-05	244	67	6	CID000002499
Drug	carbodiimide	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	8.33e-05	151	67	5	CID000009864
Drug	fasudil	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	8.33e-05	151	67	5	CID000003547
Drug	AGEPC	ACTR1A PLCXD1 ACTA1 ACTA2 TM7SF2 ACTC1 ACTG2	8.37e-05	356	67	7	CID000461545
Drug	6-trans-leukotriene B4	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2	8.80e-05	247	67	6	CID000000169
Drug	NSC339663	ACTR1A ACTA1 ACTA2 INSR ACTC1 ACTG2	9.41e-05	250	67	6	CID000003892
Drug	DFMO	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	9.42e-05	155	67	5	CID000003009
Drug	kinin 9	ACTR1A PLCXD1 ACTA1 ACTA2 INSR ACTC1 ACTG2	9.45e-05	363	67	7	CID000006026
Drug	manganese	ACTR1A DROSHA POLR2B ACTA1 ACTA2 INSR ACTC1 ACTG2 LDHA GBA2	1.00e-04	791	67	10	CID000023930
Drug	ATP betaS	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.16e-04	162	67	5	CID005311341
Drug	colchine	DPP7 ACTR1A PYCARD ACTA1 ACTA2 ACTC1 ACTG2	1.32e-04	383	67	7	CID000002833
Drug	AC1L1GZB	ACTR1A ACTA1 ACTA2 ACTC1 ACTG2	1.34e-04	167	67	5	CID000003908
Drug	NSC350593	ACTR1A PLCXD1 ACTA1 ACTA2 ACTC1 ACTG2	1.40e-04	269	67	6	CID000004364
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.15e-09	8	61	4	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.15e-09	8	61	4	DOID:0081112 (implicated_via_orthology)
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.15e-09	8	61	4	DOID:13099 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.15e-09	8	61	4	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	3.44e-09	10	61	4	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	3.44e-09	10	61	4	DOID:13832 (implicated_via_orthology)
Disease	Bell's palsy	TENM4 FARP1 ACTG2 ROBO2	6.04e-05	102	61	4	EFO_0007167
Disease	alcohol dependence (implicated_via_orthology)	INSR INSRR	1.50e-04	9	61	2	DOID:0050741 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (is_implicated_in)	ACTA2 FOXE3	2.28e-04	11	61	2	DOID:14004 (is_implicated_in)
Disease	sleep disorder (implicated_via_orthology)	INSR INSRR	2.28e-04	11	61	2	DOID:535 (implicated_via_orthology)
Disease	rheumatic heart disease (biomarker_via_orthology)	ACTA2 SOCS1	2.74e-04	12	61	2	DOID:0050827 (biomarker_via_orthology)
Disease	diabetic neuropathy (implicated_via_orthology)	INSR INSRR	3.76e-04	14	61	2	DOID:9743 (implicated_via_orthology)
Disease	Liver Cirrhosis, Experimental	DPP7 PYCARD PTRHD1 ACTA2 SOCS1 ROBO2 CIDEA	1.06e-03	774	61	7	C0023893
Disease	diabetes mellitus (implicated_via_orthology)	INSR INSRR	1.32e-03	26	61	2	DOID:9351 (implicated_via_orthology)
Disease	L lactate dehydrogenase measurement	TENM4 LDHA	1.32e-03	26	61	2	EFO_0004808
Disease	glucose metabolism disease (implicated_via_orthology)	INSR INSRR	1.53e-03	28	61	2	DOID:4194 (implicated_via_orthology)
Disease	Primary familial dilated cardiomyopathy	DSG2 ACTC1	1.76e-03	30	61	2	cv:C0340427
Disease	fatty liver disease (implicated_via_orthology)	INSR SOCS1	1.88e-03	31	61	2	DOID:9452 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NHLPLRILGYRSTME	TDRD5	41	Q8NAT2
YGRIPRGALLSMDAL	PYCARD	36	Q9ULZ3
SVLDMARHVPLYRAL	BIRC6	4381	Q9NR09
YALPHAIMRLDLAGR	ACTA1	171	P68133
VRLPVGRHMLLFNAY	ADGB	741	Q8N7X0
YALPHAIMRLDLAGR	ACTA2	171	P62736
ALPHAIMRLDLAGRD	ACTG2	171	P63267
KYAMRDLVHRLPGGN	CTNND2	931	Q9UQB3
MLPGFLHRLLAEIRY	ACTR10	311	Q9NZ32
LLEHRYPVVMAREGR	ABHD16B	351	Q9H3Z7
HILMEAAPGLLALYR	ALG12	431	Q9BV10
YGRLGLILFDHMVPL	INTS15	311	Q96N11
RYLMGERLGVHPLSC	LDHA	171	P00338
MARSPGRAYALLLLL	DSG2	1	Q14126
RERHLGLMGYQLLPL	FASTK	501	Q14296
ILLIRGDRRLHTPMY	OR9Q2	46	Q8NGE9
RRLHTPMYILLGNFA	OR11H6	71	Q8NGC7
HFALLYLEMRKGGLR	LCNL1	81	Q6ZST4
RRALMLHSDPSILGY	GIGYF1	1006	O75420
RGAPGLLMAVREDLY	DCAF4L2	376	Q8NA75
LEDARHPLKYRMLIG	FBLL1	226	A6NHQ2
MLISDRLGYHRDVPD	GALNT11	121	Q8NCW6
GMRYHLLSPEDREEL	KLHL7	266	Q8IXQ5
MAHGDLKSYLRSLRP	INSR	1106	P06213
VGLDHRLRRPMYFFL	OR6Q1	51	Q8NGQ2
ADPRLHARPMYIFLG	OR10G3	51	Q8NGC4
KLAHPYRAAVLRAME	MROH1	56	Q8NDA8
GHSPDRRYAMVLFRI	GPR52	256	Q9Y2T5
LDAGVRYLDLRIAHM	PLCXD1	96	Q9NUJ7
GKMFNALIHRYRPDL	MACF1	226	Q9UPN3
VRHPNYLGDLIMALA	TM7SF2	346	O76062
REMDPRAHRFLGLLY	RGPD3	56	A6NKT7
RLHLRYEFLMLGIQP	DAAM1	301	Q9Y4D1
RGIDYILRHMPTLHR	FRMD1	221	Q8N878
LGRNMCHLRPTLRDY	GBA2	506	Q9HCG7
RLEMYGIRLHPAKDR	FARP1	221	Q9Y4F1
RGVLLLGDAYNMRHP	SQLE	401	Q14534
KAEEHRGLLSIRYPM	ACTR1A	61	P61163
RRGHDAPMIAYDALL	ADPRHL1	271	Q8NDY3
LGYALVIFEMPHLRD	INSRR	111	P14616
YLGDRLVGRRAYHML	KLF15	21	Q9UIH9
GALERLDYPRARMAL	CERCAM	51	Q5T4B2
LRMKYPHLVAGALAA	DPP7	171	Q9UHL4
REMDPRAHRFLGLLY	RGPD4	56	Q7Z3J3
LELDRFMLYAHGPDL	DROSHA	1016	Q9NRR4
PHTAAYLQELGRMRK	PTRHD1	66	Q6GMV3
RGMLYLHEEAFVPIL	MAP3K21	246	Q5TCX8
LRSGLLNILYLHMPD	FAM178B	306	Q8IXR5
LGDDRMLGRLAQAYH	PIK3R6	421	Q5UE93
YIALIAMALAHAPGR	FOXE3	76	Q13461
GYMVHRLLLAALGRR	POLR2B	366	P30876
YMRRRHLPDLAARGT	SHISA6	326	Q6ZSJ9
SLLHYLLQAMERPGR	NPFF	51	O15130
LEHYVAAPRRMLGAP	SOCS1	151	O15524
YALPHAIMRLDLAGR	ACTC1	171	P68032
MDFLRLYLPGLHQAL	APOBR	1	Q0VD83
MEAARDYAGALIRPL	CIDEA	1	O60543
RRYHSLGLFPMDSLA	TRAK1	361	Q9UPV9
MAFALLRPVGAHVLY	TCF15	1	Q12870
ILDRILRAMGKAYHP	TRIP6	346	Q15654
YAAHALERLFTMRGP	CSE1L	521	P55060
RAYLCRVGMEVAPHL	VPS35L	336	Q7Z3J2
RLCPGDHYEVLMRLG	RIPOR3	216	Q96MK2
LYDPLTKLVHMGRRD	TENM4	2406	Q6N022
HRMLLPSGSLFFLRI	ROBO2	81	Q9HCK4
AALYHGMALALLSRL	RPAP1	976	Q9BWH6
LKLMARYGRLADPAV	ZNF346	216	Q9UL40
HDPDLAYRLALRAMR	ZSWIM4	556	Q9H7M6
FTVARYMEHRGLPLR	ZSWIM4	806	Q9H7M6