Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pathway	WP_RETT_SYNDROME	STXBP1 SCN1A SYNE2 GABBR2	2.84e-05	48	52	4	M39759
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MRPS31 GMPS CYLD PRPSAP2 LRPPRC STXBP1 SCN1A SPHKAP DLD CCT7 DLG4 GABBR2 FERMT2 SLC1A4 RHEB	1.37e-09	1139	63	15	36417873
Pubmed	Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.	RPS6KA3 CASP8	3.23e-06	2	63	2	21183680
Pubmed	The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.	WRN POLK	3.23e-06	2	63	2	25294835
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CYLD LRPPRC DNAJC13 SBF1 SPHKAP SYNE2 DLG4 GABBR2 WNK3 RHEB	8.55e-06	963	63	10	28671696
Pubmed	Semantic Similarity Analysis Reveals Robust Gene-Disease Relationships in Developmental and Epileptic Encephalopathies.	STXBP1 SCN1A	9.68e-06	3	63	2	32853554
Pubmed	TNF and IFNγ-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression.	CYLD CASP8	1.93e-05	4	63	2	38319288
Pubmed	LINC complex alterations in DMD and EDMD/CMT fibroblasts.	COPB1 SYNE2	1.93e-05	4	63	2	22555292
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	GMPS NEDD8 LRPPRC COPB1 DLD CCT7 ZYG11B	3.15e-05	495	63	7	28581483
Pubmed	Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development.	PDGFRA SCN1A	3.22e-05	5	63	2	38995010
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	MRPS31 LRPPRC DGLUCY ACAD11 MTERF3 CASP8 DLD CCT7 AADAT	4.22e-05	926	63	9	20877624
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	LRPPRC DNAJC13 STXBP1 SBF1 COPB1 DLD CCT7 DLG4 FERMT2 PLEKHG5 SLC1A4	4.73e-05	1431	63	11	37142655
Pubmed	Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development.	DLG4 CEP152	4.82e-05	6	63	2	35259752
Pubmed	Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity.	CYLD DLG4	4.82e-05	6	63	2	28973854
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	SORT1 PRPSAP2 ACAD11 COPB1 SYNE2 SLC34A2	5.11e-05	363	63	6	25036637
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GMPS LRPPRC CNNM2 ACAD11 SBF1 RPS6KA3 DLD CCT7 DLG4	6.23e-05	974	63	9	28675297
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPS31 CYLD LRPPRC DNAJC13 SBF1 ERAP2 SYNE2 MTERF3 DLD FERMT2 USP48	6.69e-05	1487	63	11	33957083
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	STXBP1 SCN1A	6.74e-05	7	63	2	25818041
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	GMPS PRPSAP2 LRPPRC ACAD11 COPB1	7.18e-05	237	63	5	29564676
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MRPS31 GMPS NEDD8 CYLD LRPPRC WRN CCT7 ZYG11B USP48	7.91e-05	1005	63	9	19615732
Pubmed	AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein.	DLG4 GABBR2	8.98e-05	8	63	2	28821923
Pubmed	Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.	RPS6KA3 RHEB	8.98e-05	8	63	2	29236692
Pubmed	CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis.	CYLD CASP8	8.98e-05	8	63	2	24098568
Pubmed	The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.	CYLD CASP8	8.98e-05	8	63	2	24577083
Pubmed	Caspase 8 inhibits programmed necrosis by processing CYLD.	CYLD CASP8	8.98e-05	8	63	2	22037414
Pubmed	Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.	PDGFRA CNGA1	8.98e-05	8	63	2	1372902
Pubmed	mSmile is necessary for bronchial smooth muscle and alveolar myofibroblast development.	PDGFRA CEP290	8.98e-05	8	63	2	21956870
Pubmed	CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1.	CYLD CASP8	8.98e-05	8	63	2	22297296
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	MRPS31 LRPPRC DGLUCY ACAD11 MTERF3 CASP8 DLD CCT7 AADAT	1.08e-04	1047	63	9	18614015
Pubmed	The small GTPase Rheb is required for spermatogenesis but not oogenesis.	DDX4 RHEB	1.15e-04	9	63	2	24713393
Pubmed	Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).	PDGFRA CNGA1	1.15e-04	9	63	2	1315306
Pubmed	Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization.	STXBP1 COPB1	1.15e-04	9	63	2	21866423
Pubmed	TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8.	CYLD CASP8	1.15e-04	9	63	2	21525013
Pubmed	Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1.	CYLD CASP8	1.44e-04	10	63	2	34853447
Pubmed	The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.	STXBP1 DLG4	1.44e-04	10	63	2	11739749
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD LRPPRC SBF1 PDGFRA GRK7 SYNE2 CEP152 WNK3	1.59e-04	861	63	8	36931259
Pubmed	Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.	CYLD CASP8	1.76e-04	11	63	2	31511692
Pubmed	Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.	SLC34A2 CNGA1	1.76e-04	11	63	2	17698926
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	GMPS LRPPRC STXBP1 COPB1 RPS6KA3 DLD CCT7	1.98e-04	665	63	7	30457570
Pubmed	Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.	CYLD CASP8	2.11e-04	12	63	2	27552911
Pubmed	Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.	STXBP1 DLG4	2.49e-04	13	63	2	15145078
Pubmed	Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.	CYLD CASP8	2.49e-04	13	63	2	36268590
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GMPS NEDD8 PRPSAP2 COPB1 RPS6KA3 DLD CCT7 FERMT2 PDCD10 USP48	2.69e-04	1455	63	10	22863883
Pubmed	Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.	COPB1 CCT7 USP48	2.84e-04	70	63	3	35008187
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	LRPPRC COPB1 CCT7	3.09e-04	72	63	3	36376293
Pubmed	Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.	COPB1 RHEB	3.34e-04	15	63	2	31672844
Pubmed	GABRA1 and STXBP1: novel genetic causes of Dravet syndrome.	STXBP1 SCN1A	3.34e-04	15	63	2	24623842
Pubmed	Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.	CYLD CASP8	3.34e-04	15	63	2	24557836
Pubmed	Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation.	CEP290 CNGA1	3.81e-04	16	63	2	27328943
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	PRPSAP2 LRPPRC DLD ZYG11B	3.92e-04	189	63	4	29449217
Pubmed	A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.	SORT1 CNNM2	4.32e-04	17	63	2	21378988
Pubmed	Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.	NEDD8 LRPPRC DLD CCT7	4.67e-04	198	63	4	24337577
Pubmed	A genome-wide association study of sleep habits and insomnia.	CEP152 L3MBTL4	4.85e-04	18	63	2	23728906
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	PRPSAP2 STXBP1 DLD CCT7 DLG4 USP48	4.91e-04	552	63	6	36293380
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	MRPS31 CYLD DNAJC13 COPB1 WRN CCT7 FERMT2	5.05e-04	777	63	7	35844135
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	DNAJC13 COPB1 CCT7 DDX4	5.13e-04	203	63	4	22083510
Pubmed	Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.	PDGFRA GRK7 RPS6KA3 SAMSN1	5.13e-04	203	63	4	19953087
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GMPS NEDD8 PRPSAP2 LRPPRC DNAJC13 SYNE2 CCT7 DMAP1 RHEB	5.24e-04	1297	63	9	33545068
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	CYLD SBF1 COPB1	5.39e-04	87	63	3	17148452
Pubmed	Discovery and refinement of loci associated with lipid levels.	SORT1 DNAJC13 ACAD11 DLG4	5.93e-04	211	63	4	24097068
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SORT1 GMPS DNAJC13 SBF1 SYNE2 CEP290 CCT7 ZYG11B	5.95e-04	1049	63	8	27880917
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	LRPPRC CNNM2 DLD CCT7 PDCD10 DMAP1	5.98e-04	573	63	6	28330616
Pubmed	mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.	STXBP1 DLG4	6.01e-04	20	63	2	23791195
Pubmed	GATOR2 complex-mediated amino acid signaling regulates brain myelination.	PDGFRA RHEB	6.01e-04	20	63	2	35022234
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	MRPS31 LRPPRC SLC9A8 COPB1 DLD CCT7 PDCD10	6.41e-04	809	63	7	32129710
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	MRPS31 NEDD8 SBF1 ALG13	7.29e-04	223	63	4	33187986
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	GMPS LRPPRC DNAJC13 COPB1 SYNE2 DLD CCT7 SLC1A4 KIAA1143	7.63e-04	1367	63	9	32687490
Pubmed	LHX2 in germ cells control tubular organization in the developing mouse testis.	PDGFRA DDX4	7.97e-04	23	63	2	36796745
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZSCAN26 WRN MPHOSPH8 USP48 KIAA1143 DMAP1	8.13e-04	608	63	6	36089195
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	CNNM2 STXBP1 SCN1A DLD GABBR2	8.44e-04	405	63	5	38187761
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	SLC9A8 FZD5 SYNE2 CEP290	8.58e-04	233	63	4	32290105
Pubmed	Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.	PDGFRA PDCD10	8.69e-04	24	63	2	20371769
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CYLD CEP290 CASP8 DLD CCT7 CEP152 FERMT2	8.74e-04	853	63	7	28718761
Pubmed	Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver.	PDGFRA ERAP2 RPS6KA3	8.80e-04	103	63	3	11752456
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	STXBP1 DLD CCT7 DLG4 SLC1A4 DDX4	9.07e-04	621	63	6	22794259
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	GMPS LRPPRC STXBP1 DLD CCT7 AADAT PLEKHG5	9.11e-04	859	63	7	31536960
Pubmed	Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.	PRPSAP2 DNAJC13 COPB1	9.31e-04	105	63	3	29491746
Pubmed	Rheb1 is required for mTORC1 and myelination in postnatal brain development.	PDGFRA RHEB	9.43e-04	25	63	2	21238928
Pubmed	Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.	LRPPRC CASP8	9.43e-04	25	63	2	19372376
Pubmed	Proteomic characterization of the human centrosome by protein correlation profiling.	CEP290 CEP152	1.02e-03	26	63	2	14654843
Pubmed	Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.	SYNE2 SHCBP1L	1.02e-03	26	63	2	25820252
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	STXBP1 DLG4	1.02e-03	26	63	2	17124501
Pubmed	Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.	STXBP1 DLG4	1.10e-03	27	63	2	19723784
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MRPS31 NEDD8 LRPPRC STXBP1 PCDHGA1 SYNE2 ZSCAN26 DLD MPHOSPH8	1.11e-03	1442	63	9	35575683
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CYLD SYNE2 CEP152 ALG13	1.13e-03	251	63	4	29778605
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GMPS LRPPRC SBF1 COPB1 SYNE2 DLD	1.17e-03	653	63	6	22586326
Pubmed	TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.	CYLD CASP8	1.36e-03	30	63	2	30420664
Pubmed	Nuclear Gene-Encoded Leigh Syndrome Spectrum Overview	LRPPRC DLD	1.36e-03	30	63	2	26425749
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	STXBP1 DLG4	1.36e-03	30	63	2	16186258
Pubmed	Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.	NEDD8 ACAD11 ZYG11B	1.37e-03	120	63	3	27565346
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	CEP290 CCT7 POLK FERMT2 PLEKHG5 ABCC10 ALG13	1.40e-03	925	63	7	28986522
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	GMPS CASP8 PDCD10 PLEKHG5 RHEB	1.44e-03	457	63	5	32968282
Pubmed	Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.	PDGFRA DDX4	1.45e-03	31	63	2	36362374
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GMPS COPB1 DLD CCT7 FERMT2 KIAA1143 RHEB	1.47e-03	934	63	7	33916271
Pubmed	Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1.	STXBP1 DLG4	1.55e-03	32	63	2	26758845
Pubmed	Genome-wide association study identifies eight loci associated with blood pressure.	CYP1A1 CNNM2	1.55e-03	32	63	2	19430483
Pubmed	CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.	PRPSAP2 LRPPRC COPB1 SCN1A CEP290	1.60e-03	468	63	5	36042349
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	COPB1 RPS6KA3	1.64e-03	33	63	2	26296893
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	GMPS LRPPRC COPB1 DLD CCT7 PDCD10	1.76e-03	707	63	6	19738201
Cytoband	3q24	GMPS GRK7	8.40e-04	31	63	2	3q24
Cytoband	3q22.1	DNAJC13 ACAD11	1.54e-03	42	63	2	3q22.1
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	MRPS31 DNAJC13 SYNE2 MTERF3 CEP290 WRN MPHOSPH8 POLK PDCD10 USP48	3.48e-06	656	63	10	M18979
Coexpression	GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN	CYLD FZD5 GRK7 SPHKAP CASP8 CNGA1	6.27e-06	189	63	6	M9724
Coexpression	LEE_NEURAL_CREST_STEM_CELL_DN	DGLUCY FZD5 SYNE2 CEP290 SLC1A4	1.14e-05	122	63	5	M10276
Disease	Rett Syndrome, Atypical	STXBP1 GABBR2	4.47e-05	5	63	2	C2748910
Disease	Neurodevelopmental Disorders	STXBP1 SCN1A DLG4 ALG13	4.78e-05	93	63	4	C1535926
Disease	Early Childhood Epilepsy, Myoclonic	STXBP1 SCN1A	1.25e-04	8	63	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	STXBP1 SCN1A	1.25e-04	8	63	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	STXBP1 SCN1A	1.25e-04	8	63	2	C0338479
Disease	Myoclonic Encephalopathy	STXBP1 SCN1A	1.25e-04	8	63	2	C0438414
Disease	Leigh syndrome	LRPPRC DLD	1.25e-04	8	63	2	cv:C0023264
Disease	Benign Infantile Myoclonic Epilepsy	STXBP1 SCN1A	1.25e-04	8	63	2	C0751120
Disease	Myoclonic Absence Epilepsy	STXBP1 SCN1A	1.25e-04	8	63	2	C0393703
Disease	Myoclonic Epilepsy	STXBP1 SCN1A	1.60e-04	9	63	2	C0014550
Disease	C-C motif chemokine 21 measurement	DNAJC13 ACAD11	2.00e-04	10	63	2	EFO_0008048
Disease	Epilepsy, Myoclonic, Infantile	STXBP1 SCN1A	2.00e-04	10	63	2	C0917800
Disease	Myoclonic Astatic Epilepsy	STXBP1 SCN1A	2.44e-04	11	63	2	C0393702
Disease	Infantile Severe Myoclonic Epilepsy	STXBP1 SCN1A	3.45e-04	13	63	2	C0751122
Disease	Non-Small Cell Lung Carcinoma	CYLD SLC34A2 CASP8 RHEB	3.51e-04	156	63	4	C0007131
Disease	Early infantile epileptic encephalopathy with suppression bursts	STXBP1 SCN1A	5.28e-04	16	63	2	C0393706
Disease	heart disease (biomarker_via_orthology)	CYP1A1 CASP8	5.98e-04	17	63	2	DOID:114 (biomarker_via_orthology)
Disease	Epilepsy, Cryptogenic	STXBP1 SCN1A ALG13	7.28e-04	82	63	3	C0086237
Disease	Awakening Epilepsy	STXBP1 SCN1A ALG13	7.28e-04	82	63	3	C0751111
Disease	Aura	STXBP1 SCN1A ALG13	7.28e-04	82	63	3	C0236018
Disease	X-24309 measurement	DNAJC13 ACAD11	8.32e-04	20	63	2	EFO_0800872
Disease	disease of metabolism (implicated_via_orthology)	DLD RHEB	9.18e-04	21	63	2	DOID:0014667 (implicated_via_orthology)
Disease	Micronuclei, Chromosome-Defective	CYP1A1 POLK	1.41e-03	26	63	2	C1449861
Disease	Micronuclei, Genotoxicant-Induced	CYP1A1 POLK	1.41e-03	26	63	2	C1449862
Disease	Epilepsy	STXBP1 SCN1A ALG13	1.66e-03	109	63	3	C0014544
Disease	Glioblastoma Multiforme	PDGFRA RPS6KA3 POLK	1.75e-03	111	63	3	C1621958
Disease	Epileptic encephalopathy	GABBR2 ALG13	1.88e-03	30	63	2	C0543888

Protein segments in the cluster

Peptide	Gene	Start	Entry
VKELIEEKAVKMGVL	AADAT	366	Q8N5Z0
AIKGAMKKLEIELEL	CEP152	831	O94986
EKGKPLVVVINEKLM	ALG13	91	Q9NP73
LMDIIGKEKIGLKQI	DDX4	426	Q9NQI0
GKPLVIDKLKEMAKV	ACAD11	416	Q709F0
KVLSEKVIIFGMGKR	CYP1A1	441	P04798
GEVKGKGITMLEEIK	PDGFRA	251	P16234
KGITMLEEIKVPSIK	PDGFRA	256	P16234
LEVKKGMLVGIVGKV	ABCC10	621	Q5T3U5
MLIKVKTLTGKEIEI	NEDD8	1	Q15843
VKVVLKGLKVMNLLE	NLRP10	71	Q86W26
VLKKGDLSVEEVMKI	KIAA1143	61	Q96AT1
VVTELMKGGELLDKI	RPS6KA3	491	P51812
PGLTQDIIMKILEKK	PDCD10	56	Q9BUL8
ALKKVIIMILNGEKL	COPB1	41	P53618
KEKNVQGIIEILKGM	LRPPRC	451	P42704
TDIVKVMKIKLGPAL	L3MBTL4	581	Q8NA19
EGKMLEAKKLLPAVL	SBF1	576	O95248
IKVIHGKLLDMVGKV	RHEB	96	Q15382
ILAGLIGKKMGIEKL	FBXO43	481	Q4G163
IGKKMGIEKLDILTE	FBXO43	486	Q4G163
GGTKTDKLEKLMIRI	FZD5	436	Q13467
VVLKMVTEIKKIPGI	GMPS	661	P49915
KKIKALEQMLLELGV	DMAP1	336	Q9NPF5
TIPELEKTIGLMKKV	CEP290	2126	O15078
TKEKINLLKGIIGLM	EDDM13	31	A0A1B0GTR0
ALSLKKVPEKMVVIG	DLD	206	P09622
MEKRVILGEGKLDIL	CASP8	146	Q14790
AIIKGAGLVMKAIIE	DNAJC13	576	O75165
EKVMEIKLIKGPKGL	DLG4	156	P78352
KLLKLIELGMEGKVI	ERAP2	836	Q6P179
IIKDQKLLVIVGGML	GABBR2	591	O75899
KKIAERLGVEMGKVQ	PRPSAP2	36	O60256
IKEEKMLGILVQHKV	DGLUCY	566	Q7Z3D6
KEGLEIMIGKKKGIQ	CYLD	581	Q9NQC7
IGGVMLKLVEKLDVK	FERMT2	41	Q96AC1
GGEKMALLEKEILEK	GRK7	231	Q8WTQ7
LGVFKVKQMIEIIGL	CFAP47	481	Q6ZTR5
GEKKILAGKLEMTLE	DYSF	1976	O75923
VEKILDMKTEGGKVL	MPHOSPH8	61	Q99549
KDIKQMLLFLKDVGI	MTERF3	186	Q96E29
GLMAKVKVLIKVLDV	PCDHGA1	326	Q9Y5H4
KKDLLGIIKGMKVEL	MRPS31	96	Q92665
LMLVTVVAGVLIVKK	SORT1	766	Q99523
PMINELVEEKKILKG	SPHKAP	1571	Q2M3C7
KRGLLLLKEAGMEKI	RSAD2	106	Q8WXG1
GMVELVKIGKEKLAH	SYNE2	4746	Q8WXH0
IKKGDIIDIICKTPM	SAMSN1	186	Q9NSI8
DIIIKGVGKREEIMI	SHCBP1L	441	Q9BZQ2
LGILMGAVIKIIEFK	SLC9A8	96	Q9Y2E8
LDDLLQLKMIGIKKV	CCT7	186	Q99832
MLLENKAVKKAGVGI	WRN	126	Q14191
LKAVVGEKIMHDVIK	STXBP1	6	P61764
IGLKDKKIMEILATA	SDCBP2	241	Q9H190
KIKGGANLLIKEDMI	SCN1A	1946	P35498
LEEKGKQILMKDGLL	CNGA1	591	P29973
GIIEIEIKPLRKMEK	CNNM2	171	Q9H8M5
IMIVKILGSVLKGQV	SLC34A2	381	O95436
IVPAMKKKSLGEVLL	PLEKHG5	91	O94827
EKTKPEILKLVVTGM	ZYG11B	356	Q9C0D3
LVGSKIVEMKDIIVL	SLC1A4	276	P43007
AGMEGLDKEKINKII	POLK	26	Q9UBT6
GIGKVTEKMLKALGI	POLK	356	Q9UBT6
KQKILVEEMAPLKGV	ZSCAN26	146	Q16670
KMEGKKLQLGIEEDL	USP48	376	Q86UV5
ILKGKKCIVLVTELM	WNK3	216	Q9BYP7