Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesschromatin remodeling

KMT2A CTR9 MYOCD MPHOSPH8 PBRM1 ZNF274

5.30e-05741206GO:0006338
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell differentiation

MYOCD PBRM1

1.35e-0418202GO:0060947
GeneOntologyBiologicalProcesschromatin organization

KMT2A CTR9 MYOCD MPHOSPH8 PBRM1 ZNF274

1.52e-04896206GO:0006325
GeneOntologyBiologicalProcessregulation of heterochromatin formation

KMT2A MPHOSPH8

2.43e-0424202GO:0031445
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

KMT2A CTR9 MYOCD MPHOSPH8

2.55e-04330204GO:0040029
GeneOntologyBiologicalProcessprotein-DNA complex organization

KMT2A CTR9 MYOCD MPHOSPH8 PBRM1 ZNF274

2.74e-04999206GO:0071824
DomainBROMODOMAIN_2

KMT2A PBRM1

7.85e-0441192PS50014
DomainBROMO

KMT2A PBRM1

8.24e-0442192SM00297
DomainBromodomain

KMT2A PBRM1

8.24e-0442192IPR001487
Domain-

KMT2A PBRM1

8.24e-04421921.20.920.10
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

KMT2A ZNF277 CTR9 MPHOSPH8 TAF15 PBRM1 EDC4 EIF4G2

9.16e-07149720831527615
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

KMT2A TAF15 PBRM1 EDC4

4.33e-0619520419454010
Pubmed

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

KMT2A CTR9

4.71e-06620220541477
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KMT2A CTR9 OSBPL3 MPHOSPH8 TAF15 PBRM1 EIF4G2

4.92e-06129420730804502
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

KMT2A CTR9 PBRM1

5.73e-066120320305087
Pubmed

MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation.

EDC4 EIF4G2

6.59e-06720219114715
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

KMT2A CTR9 PBRM1

8.32e-066920328481362
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

KMT2A CTR9 MPHOSPH8 TAF15 PBRM1 EIF4G2

1.65e-05101420632416067
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

KMT2A CTR9 TAF15 PBRM1 EIF4G2

1.96e-0560520528977666
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

KMT2A MPHOSPH8 KIF5A PBRM1 EDC4

2.66e-0564520525281560
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

CTR9 PBRM1 EDC4 EIF4G2

3.50e-0533220432786267
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

TSHZ2 PBRM1 EIF4G2 ZNF274

4.95e-0536320414691545
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

TAF15 PBRM1

7.89e-052320230962207
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

CTR9 TAF15 EIF4G2 ZNF274

1.74e-0450320436217030
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

OSBPL3 TAF15 KIF5A PBRM1 EDC4

1.77e-0496320528671696
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

MYOCD PBRM1

2.07e-043720224335282
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

KMT2A PBRM1

2.67e-044220235705031
Pubmed

Functional proteomics mapping of a human signaling pathway.

TOPORS CTR9 PBRM1 EIF4G2

3.22e-0459120415231748
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

CTR9 TAF15 PBRM1

3.56e-0424420329884807
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

DSPP CTR9 TAF15 KIF5A EDC4

4.06e-04115320529845934
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

ZNF277 OSBPL3 EIF4G2

4.19e-0425820337794589
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

KMT2A CTR9 PBRM1

4.68e-0426820333640491
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

KMT2A TAF15 PBRM1 EDC4

4.70e-0465320422586326
Pubmed

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.

CTR9 PBRM1

5.09e-045820227869233
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

KMT2A CTR9 PBRM1

5.37e-0428120324163370
InteractionCDK9 interactions

KMT2A CTR9 BCL10 TAF15 EDC4 EIF4G2

3.89e-05685206int:CDK9
InteractionTOP1 interactions

TOPORS KMT2A CTR9 MPHOSPH8 TAF15 PBRM1

4.25e-05696206int:TOP1
InteractionRNF8 interactions

CTR9 BCL10 TAF15 C2CD6 PBRM1

4.65e-05421205int:RNF8
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TSHZ2 MYOCD FAM110B

6.94e-051812037e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ2 KMT2A MPHOSPH8

7.29e-051842035350b58aa9979631228835d11eb45ddf81d08bff
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYT1L TOPORS KIF5A

7.89e-051892038e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MYOCD FAM110B

8.92e-051972035f6fce382f273e789ffbb75b63e9b4e87519918e
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MYOCD FAM110B

8.92e-05197203c7b33d64e5cba3a8fc6f2d6aa85ebc83893195de
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TSHZ2 KMT2A MPHOSPH8

9.19e-051992033e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DSPP MYOCD KIF5A

9.19e-05199203b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCellmild-CD4+_Tcm|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TSHZ2 KMT2A MPHOSPH8

9.19e-0519920306c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L FAM110B EIF4G2

9.33e-0520020384e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

MYT1L KIF5A EIF4G2

9.33e-05200203979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L FAM110B EIF4G2

9.33e-052002031decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L EIF4G2

4.97e-0474202a50df7f4f7847b8aeff3fc6d521a69b50e05c719
ToppCell(04)_Pre-ciliated-(4)_1wkpi|(04)_Pre-ciliated / shred by cell type and Timepoint

MYT1L MYOCD

7.18e-0489202846c2fec66981bf41be64a2e1812ec1b1b833961
ToppCell368C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

BCL10 TAF15

8.01e-049420256176a9435ef197f07034bbbd16b85016a89ad3c
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TSHZ2 DSPP

8.18e-0495202ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

DSPP MYOCD

8.35e-049620231ed9e073e30d740b46c8b3f01ba0de94a701995
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

DSPP MYOCD

8.35e-0496202cd0b9812727cad937cf840360a87a2382e570d39
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DSPP MYOCD

8.35e-0496202f31bed26ed9bcaf82d443de304372991136b11e7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L EIF4G2

8.35e-049620256e993d37b7958abe56682422536045550e29b41
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MYT1L EIF4G2

1.13e-031122029c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOCD C2CD6

1.32e-03121202da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

TSHZ2 ZNF277

1.71e-0313820205de2cef97c0912fb23f138dd45348f565a14d74
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYT1L TSHZ2

2.02e-031502027a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYT1L TSHZ2

2.02e-03150202e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

TSHZ2 KMT2A

2.04e-03151202999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

TOPORS FAM110B

2.15e-031552029d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD6 KIF5A

2.15e-03155202441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 MYOCD

2.18e-03156202d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 MYOCD

2.18e-03156202363f1b661048d25895e2b8681c82894c957b29c0
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|World / disease group, cell group and cell class (v2)

TSHZ2 C2CD6

2.21e-0315720223879e65a6acc33d9aad096cd23604a77b0ac9c2
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

MYOCD KIF5A

2.29e-03160202d783d29150033e9181c0e30870070268fed3fd85
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L KIF5A

2.32e-0316120269f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KMT2A EDC4

2.32e-031612022849fbc9611af208241b33da3cd18290aafe426b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ2 REV3L

2.35e-0316220280317c4253bf8e897782e562f29835f181c65b98
ToppCellICU-SEP-Lymphocyte-T_NK-CD4_Naive|ICU-SEP / Disease, Lineage and Cell Type

TSHZ2 C2CD6

2.37e-03163202415e67aaae7ccd97a003b4b31b27eed94737deca
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYT1L KIF5A

2.40e-03164202be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L KIF5A

2.43e-0316520202cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L KIF5A

2.43e-031652026d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF277 REV3L

2.46e-03166202b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF277 REV3L

2.46e-0316620213027ae342994db4540e64eb910df1f42b160931
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.49e-03167202c7d1e84af1f4d7430858287520ac2cfa36203642
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TSHZ2 ZNF274

2.49e-0316720278d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.49e-031672024e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.49e-0316720218ad85751bd892309627eefc357eb28ec5a7c300
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ2 KIF5A

2.49e-03167202ced6ed9b412739c6ced622523347c10295edbf53
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.52e-031682024a2e08b047f7170ae4b95eac9b2b128e55beee4a
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYT1L OSBPL3

2.52e-031682026c758eb120faf06ff72d157b495e399191c79ec9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.52e-031682023e09516e819cf140a6dbf8f85247d3f08aa35bb8
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM110B REV3L

2.55e-03169202c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYT1L KIF5A

2.55e-03169202b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 OSBPL3

2.58e-031702023174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.58e-03170202ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYT1L FAM110B

2.58e-031702025570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.58e-031702024aa9e597f6550ac8cac3137a98be58e71efd07d6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.58e-03170202ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MYT1L MYOCD

2.61e-03171202bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.61e-031712020417fa805ca0acb7e9f6a30bc7b6bdbaba77844d
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

OSBPL3 EDC4

2.61e-0317120226b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD FAM110B

2.67e-031732021cff815536f620e32b9805666e1aa711462c2d25
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD FAM110B

2.67e-0317320231ea04e65876c42b90245d280f0b6439bfffbace
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 OSBPL3

2.67e-031732028335b77f730ed43fc348a005566e73a103c6774b
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYT1L KIF5A

2.70e-03174202742c73c9e090848b464323cb17579b86658c6792
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.70e-03174202271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYT1L KIF5A

2.70e-031742027fed9722e64c60843092f2ba71256e3043011ef6
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TSHZ2 EDC4

2.70e-03174202263e6d9c3d59ffc1e88baa1fd20b8c0e5be46ffa
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOCD FAM110B

2.73e-03175202798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOCD FAM110B

2.73e-03175202294a70786260c9a2b1ba16c88819d786698609e7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 MYOCD

2.73e-03175202d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

MYT1L OSBPL3

2.76e-03176202d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.76e-0317620204dad262929581872e5bbc66cd8182c963e7e52f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KMT2A EDC4

2.79e-031772029edfb50856f5e10672ab194ce0076d6a190e64de
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MYOCD

2.82e-031782020fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.85e-03179202228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OSBPL3 FAM110B

2.85e-03179202d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYT1L KIF5A

2.85e-03179202af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 FAM110B

2.85e-0317920240c65e8623547aeb80f9cd2366e29072467ce069
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSHZ2 MYOCD

2.85e-0317920202c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.85e-03179202b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.88e-03180202368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 KMT2A

2.88e-03180202423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 KMT2A

2.88e-03180202dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TSHZ2 FAM110B

2.92e-031812029b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.92e-031812027f99002a6411117cc2361334c7c9228e20c574b4
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

TSHZ2 OSBPL3

2.92e-03181202f2315414e714ac86211546a935660c4be6e85f1b
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L KIF5A

2.92e-03181202fb4df9a128761abe5c6310a30d7b2f7f2fdef46d
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KMT2A OSBPL3

2.95e-03182202626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 FAM110B

2.95e-031822023dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOCD REV3L

2.95e-0318220252274af3136d4fd4a495f5882618444661421f0f
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOCD REV3L

2.95e-03182202dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSHZ2 REV3L

2.95e-03182202ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KMT2A OSBPL3

2.95e-03182202a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

TSHZ2 MYOCD

2.98e-03183202de08f9ea02b7244d5a8788064631d10f06565337
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSHZ2 MYOCD

2.98e-0318320212daaea821e49bc94a01e2496331e92a80d27339
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TSHZ2 FAM110B

2.98e-03183202f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSHZ2 MYOCD

2.98e-031832027eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD KIF5A

3.01e-03184202ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYT1L KIF5A

3.01e-031842023e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD KIF5A

3.01e-031842022cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MYT1L KIF5A

3.01e-03184202eac2a9089913f33a961ba11519b53645790f2056
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD KIF5A

3.01e-031842022b19a8c5f823e00812908b23e66bb4e563278aff
Diseasenon-Hodgkin lymphoma (is_implicated_in)

KMT2A BCL10

5.90e-0517202DOID:0060060 (is_implicated_in)
Diseaseinterleukin-8 measurement

MYT1L KMT2A

2.01e-0431202EFO_0004811
Diseaseeye morphology measurement

MYT1L FAM110B EIF4G2

4.13e-04218203EFO_0007858
DiseaseOsteosarcoma

TOPORS TAF15

4.63e-0447202C0029463
Diseaserisk-taking behaviour

MYT1L TSHZ2 PBRM1 REV3L

1.55e-03764204EFO_0008579
DiseaseNeurodevelopmental Disorders

MYT1L KMT2A

1.80e-0393202C1535926
Diseasespontaneous preterm birth

MYT1L TOPORS

2.12e-03101202EFO_0006917
Diseaseinsomnia measurement

MYT1L KMT2A PBRM1

3.17e-03443203EFO_0007876
Diseasecoronary artery calcification

MYT1L OSBPL3 EIF4G2

3.31e-03450203EFO_0004723

Protein segments in the cluster

PeptideGeneStartEntry
SNGNDDANSESDNNS

DSPP

471

Q9NZW4
DANSESDNNSSSRGD

DSPP

476

Q9NZW4
RTDADSESDNSDNNT

TAF15

221

Q92804
LQQRDSQDASAEQSD

EDC4

866

Q6P2E9
KNTDNSEDSRAEDNF

PBRM1

1111

Q86U86
TLNQSDQDNSTADAS

C2CD6

416

Q53TS8
DQDNSTADASKNDES

C2CD6

421

Q53TS8
TRRDDNSAANNSANE

EIF4G2

56

P78344
NQDLASGSENDRNDS

MYOCD

196

Q8IZQ8
NNLSRSNSDESNFSE

BCL10

131

O95999
NSNSNSDSDEDEQRK

CTR9

1036

Q6PD62
SDCEQSQDSNSDLRN

FAM110B

316

Q8TC76
SQDSNSDLRNDDSAN

FAM110B

321

Q8TC76
DNGNATDINDNRSDL

KIF5A

996

Q12840
SDSDNNNSDDCGNIL

KMT2A

2831

Q03164
SLNNDIFEANSDSDQ

MPHOSPH8

126

Q99549
SDISDNLSLDNLSND

OSBPL3

476

Q9H4L5
LQNSSQLDNSVSDDS

REV3L

1606

O60673
DNRESQANSGALDTN

ZNF274

401

Q96GC6
NQDAENESLLSDASD

TSHZ2

76

Q9NRE2
SDSESDLTAQEQNEN

ZNF277

411

Q9NRM2
VQTNDDLNNDSDDSS

TOPORS

461

Q9NS56
NSNTSNSLEDDSDKN

MYT1L

226

Q9UL68