Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponenttransferase complex

MED24 ANAPC11 AMFR IGF1R WDFY3 REV3L PHF20 PHF20L1 CXXC1

8.32e-05963419GO:1990234
GeneOntologyCellularComponentNSL complex

PHF20 PHF20L1

2.04e-0411412GO:0044545
DomainZnf_FYVE_PHD

ZFYVE26 RIMS1 WDFY3 PHF20 PHF20L1 CXXC1

7.69e-07147416IPR011011
DomainDUF3776

PHF20 PHF20L1

4.70e-062412PF12618
DomainDUF3776

PHF20 PHF20L1

4.70e-062412IPR022255
Domain-

ANAPC11 AMFR ZFYVE26 RIMS1 WDFY3 PHF20 PHF20L1 CXXC1

4.99e-064494183.30.40.10
DomainZnf_RING/FYVE/PHD

ANAPC11 AMFR ZFYVE26 RIMS1 WDFY3 PHF20 PHF20L1 CXXC1

5.87e-06459418IPR013083
DomainZnf_FYVE-rel

ZFYVE26 RIMS1 WDFY3

5.60e-0534413IPR017455
DomainZnf_FYVE

ZFYVE26 RIMS1 WDFY3

7.85e-0538413IPR000306
DomainZF_FYVE

ZFYVE26 RIMS1 WDFY3

9.17e-0540413PS50178
DomainZinc_finger_PHD-type_CS

PHF20 PHF20L1 CXXC1

3.90e-0465413IPR019786
DomainSpectrin

SPTA1 SYNE2

1.16e-0323412PF00435
DomainZF_PHD_1

PHF20 PHF20L1 CXXC1

1.22e-0396413PS01359
DomainTUDOR

PHF20 PHF20L1

1.59e-0327412SM00333
DomainFYVE

ZFYVE26 WDFY3

1.84e-0329412PF01363
DomainFYVE

ZFYVE26 WDFY3

1.84e-0329412SM00064
DomainSpectrin_repeat

SPTA1 SYNE2

1.84e-0329412IPR002017
DomainTudor

PHF20 PHF20L1

1.97e-0330412IPR002999
DomainSpectrin/alpha-actinin

SPTA1 SYNE2

2.24e-0332412IPR018159
DomainSPEC

SPTA1 SYNE2

2.24e-0332412SM00150
DomainPHD

PHF20 CXXC1

1.18e-0275412PF00628
DomainZnf_PHD-finger

PHF20 CXXC1

1.30e-0279412IPR019787
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

PHF20 PHF20L1 CXXC1

7.71e-0538313MM17073
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

PHF20 PHF20L1 CXXC1

1.04e-0442313M48018
Pubmed

Complex Modes of Inheritance in Hereditary Red Blood Cell Disorders: A Case Series Study of 155 Patients.

PIEZO1 SPTA1

1.42e-06242234201899
Pubmed

Identification of substrates of human protein-tyrosine phosphatase PTPN22.

LCK SPTA1

5.10e-05942216461343
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

MED24 AMFR LCK GTF3C1 LCORL SOBP TDP2 SYNE2

5.16e-05112442821900206
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

RIMS1 WDFY3

9.32e-051242227824329
Pubmed

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

PHF20 PHF20L1

1.91e-041742220479123
Pubmed

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

BCAS2 SYNE2

2.15e-041842233361760
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZFYVE26 RIMS1 TRANK1

2.74e-041044239205841
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

IFT122 MYOM2 RIMS1 GTF3C1 PHF20L1 CXXC1 SPTA1 SYNE2

2.87e-04144242835575683
Pubmed

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

IFT122 RFX3

3.24e-042242225294941
Pubmed

The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.

LCK SPTA1

4.90e-04274228390965
Pubmed

Analysis of mouse embryonic patterning and morphogenesis by forward genetics.

IFT122 DISP1

7.34e-043342215755804
Pubmed

Tudor, MBT and chromo domains gauge the degree of lysine methylation.

PHF20 PHF20L1

7.34e-043342216415788
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

N4BP2L2 SPOCK2 IFT122 WDFY3 REV3L TDP2 TNPO2

8.04e-04128542735914814
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

C17orf75 WDFY3 REV3L HUS1 SYNE2

9.93e-0463842531182584
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

IGF1R LCK MYLK3 CXXC1

1.05e-0337242422939624
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

IGF1R PHF20L1 TNPO2

1.05e-0316542316107646
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

IFT122 RFX3

1.08e-034042232317081
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

PHF20L1 BCAS2 SYNE2

1.15e-0317042323314748
GeneFamilyPHD finger proteins

PHF20 PHF20L1 CXXC1

4.39e-049030388
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE26 WDFY3

1.20e-033130281
GeneFamilyTudor domain containing

PHF20 PHF20L1

1.71e-0337302780
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

N4BP2L2 SPOCK2 TRANK1 REV3L LCK CDC42SE2 PHF20 PHF20L1 SSH1 TDP2 PIEZO1

1.63e-0514924211M40023
CoexpressionGSE4142_PLASMA_CELL_VS_GC_BCELL_UP

PDE3A C17orf75 PHF20L1 TDP2 CD163

1.66e-05200425M6390
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

5.36e-071694256d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCellHealthy_donor-MAIT|World / disease group, cell group and cell class (v2)

SPOCK2 LCK GTF3C1 BCAS2 SYNE2

5.84e-071724256524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCellmild_COVID-19_(asymptomatic)-gd_T|World / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

6.01e-07173425b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 CDC42SE2 PHF20 BCAS2 SYNE2

6.36e-07175425f456d8d958b71f7a942b718605712593d9de1bfd
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

7.72e-071824259ba85f621a846531a2a7861e9df695d288c9e149
ToppCellmild_COVID-19_(asymptomatic)-gd_T|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

8.60e-071864255fa3ed834898aa06aae15a8ade7ab93a6e4744f8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

9.80e-07191425142f98cabf8737b28369315b3d7a0797ded88e03
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.01e-0619242558a7829b411b02b422ef75e2277a868969cc23e8
ToppCell(210)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.01e-0619242508dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell(21)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.01e-06192425b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.01e-06192425ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPOCK2 TRANK1 LCK CDC42SE2 SYNE2

1.08e-06195425662b50a2aa97373bf343b88caace9717049c722a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPOCK2 TRANK1 LCK CDC42SE2 SYNE2

1.08e-061954259b7157b5e4b81bc35b0e6d9b954279160ea57324
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.08e-061954259990440bda7fac5d00ef80444fab07459be625e1
ToppCellHealthy/Control-gd_T|Healthy/Control / Disease group and Cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.11e-06196425a6f9e55cd1cd7facadb3f508bded68023c997f3f
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.11e-061964256beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.11e-06196425c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 IGF1R LCK CDC42SE2 SYNE2

1.11e-06196425c4e7133c609bcbc48c4947ea0aa1a7d9d7251b04
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.11e-06196425418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.11e-06196425581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellInfluenza_Severe-NK|Influenza_Severe / Disease group and Cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.14e-06197425d0f58ee4c02573d214deb210bb7efd3d6118f267
ToppCellT_cells-CCR7+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

1.14e-06197425904430779c42b51d3eec62cf0cdd501b17058d8b
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 TRANK1 LCK CDC42SE2 SYNE2

1.14e-061974250b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 TRANK1 LCK CDC42SE2 SYNE2

1.14e-06197425b3876076684781fb8384117f2cf367d828985986
ToppCellICU-NoSEP-Lymphocyte-T_NK|ICU-NoSEP / Disease, Lineage and Cell Type

SPOCK2 MYOM2 LCK CDC42SE2 SYNE2

1.14e-06197425951bb4c1e6f5c5fd7e7d58b36eb3f31e9201fb66
ToppCellHealthy_donor-CD4+_CTL|World / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK CDC42SE2 SYNE2

1.14e-061974251dee9b905ef36e567acc1094a3c0e41f56d1261e
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-06198425a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell356C-Lymphocytic|356C / Donor, Lineage, Cell class and subclass (all cells)

SPOCK2 MYOM2 LCK CDC42SE2 SYNE2

1.17e-06198425d5f73f6abaf91780fbc16a1144a73ad863abb398
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

1.17e-061984258a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-06198425a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCellCOVID_vent-Lymphocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

SPOCK2 TRANK1 LCK CDC42SE2 SYNE2

1.17e-06198425ee80f647317377081b4bd194ee2801f556b3a53b
ToppCellsevere_influenza-NK|severe_influenza / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-06198425d431beb870ff5e165d98febfb27049d729e37dc8
ToppCellHealthy_donor-gd_T|World / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-061984250c3475936f148f2c026501c61b43bcb94d320c48
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-0619842576aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-06198425df399674345c45738d765a8354ea8d1484572c34
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPOCK2 LCK CDC42SE2 SCN2B SYNE2

1.17e-061984257608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCellCOVID-19_Mild-Lymphoid_T/NK-gd_T|COVID-19_Mild / Disease group, lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.17e-061984256aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

1.17e-0619842533a3b279c9ff3b762e52d060dae062167ca2239b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

N4BP2L2 SPOCK2 LCK CDC42SE2 SYNE2

1.20e-06199425db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 BCAS2 SYNE2

1.20e-061994253003badee037d4d63a8018a74c0aea213d049e43
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-gd_T|Influenza_Severe / Disease, condition lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.20e-06199425b1ecc8aa5a98fe42d678ab07b310d62ebaacdecf
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T|COVID-19_Mild / Disease, condition lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.23e-062004256560753d3df2f87860b52052d4881aa45410f666
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-NK|Influenza_Severe / Disease, condition lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.23e-0620042504ac14414d550b14dc46d682e7af9dd43982211a
ToppCellsevere-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPOCK2 LCK CDC42SE2 GTF3C1 SYNE2

1.23e-062004258a849d0ef244aa2666da2d31bd0731fb04e40911
ToppCellsevere-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPOCK2 LCK CDC42SE2 GTF3C1 SYNE2

1.23e-062004256aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK|ICU-NoSEP / Disease, condition lineage and cell class

SPOCK2 MYOM2 LCK CDC42SE2 SYNE2

1.23e-0620042531c06b73292015e69038e52ae67322f458f37c71
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

SPOCK2 MYOM2 LCK GTF3C1 SYNE2

1.23e-06200425f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellsevere_COVID-19-gd_T|World / disease group, cell group and cell class (v2)

SPOCK2 LCK TECTA SYNE2

9.43e-06141424d2575900775ce6801364c2d4eed8d213f30fa0e0
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|367C / Donor, Lineage, Cell class and subclass (all cells)

SPOCK2 LCK C12orf50 SYNE2

1.05e-0514542429422c908d58081e6a748e362a7ac41bf001444c
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

LANCL3 C17orf75 LCK SYNE2

1.27e-05152424b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-MAIT|Lung / Manually curated celltypes from each tissue

SPOCK2 LCK GTF3C1 SYNE2

1.37e-0515542472c61be0a8d3ee10600a33c58fb01c35fd3f14d4
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

SPOCK2 MYOM2 LCK SYNE2

1.59e-05161424b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 REV3L CDC42SE2 SYNE2

1.63e-0516242480317c4253bf8e897782e562f29835f181c65b98
ToppCellsevere_COVID-19-gd_T|severe_COVID-19 / disease group, cell group and cell class (v2)

SPOCK2 LCK TECTA SYNE2

1.75e-0516542449f31173da71c1841616d69b7062852ad7a5090f
ToppCellBAL-Severe-cDC_2|Severe / Compartment, Disease Groups and Clusters

LANCL3 SPOCK2 LCK SYNE2

1.79e-05166424602a72a607534d5f21eddd2c7a52a57084f4920f
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPOCK2 TRANK1 LCK TNPO2

1.84e-05167424dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellControl-Lymphocyte-T_NK-MAIT|Control / Disease, Lineage and Cell Type

SPOCK2 LCK GTF3C1 SYNE2

1.92e-051694248c2aac193a9c500f01a99a2ee530839c851b6222
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A MYOM2 MYLK3 CD163

1.97e-051704243f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellInfluenza_Severe-gd_T|Influenza_Severe / Disease group and Cell class

SPOCK2 MYOM2 LCK SYNE2

1.97e-0517042459009c5a504ea8c6b4f6697299db219fd5edf7d6
ToppCellHealthy/Control-MAIT|World / Disease group and Cell class

SPOCK2 GTF3C1 BCAS2 SYNE2

2.01e-0517142461515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPOCK2 LCK CDC42SE2 SYNE2

2.21e-051754248269721389a3ce98681460e6393f2cff816eaa25
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPOCK2 LCK GTF3C1 SYNE2

2.21e-05175424cc2428150987911d0d382e8177918724aa69f85c
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CXXC1 SYNE2

2.26e-051764246b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPOCK2 LCK GTF3C1 SYNE2

2.26e-05176424003076f1a983409ddf31b9c19e61c1facdd72566
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPOCK2 LCK GTF3C1 SYNE2

2.31e-05177424605f71515c877bb4de4121675ec8c1318a2500a7
ToppCellControl-Lymphocyte-T_NK-CD4_CTL|Control / Disease, Lineage and Cell Type

SPOCK2 LCK GTF3C1 SYNE2

2.36e-0517842432fbb7a8d7daa7cb37f42923514acbb9090e6811
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 IGF1R CDC42SE2 SYNE2

2.36e-0517842473936c2e7e8855b4ab65cad425686513dba331a3
ToppCellIIF-Lymphocyte-T_NK-gdT|IIF / Disease, Lineage and Cell Type

SPOCK2 LCK GTF3C1 SYNE2

2.36e-051784243344d1328fd9c570c3a4b2629edec627a442d0e0
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 SYNE2

2.41e-05179424b0585a8e596c3d8e434af943e65207fa5877600d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK CDC42SE2 SYNE2

2.46e-0518042405f14cd367021891166825a8aac171227e2bcd97
ToppCellAdult-Immune-natural_killer_cell-D175|Adult / Lineage, Cell type, age group and donor

MYOM2 LCK CDC42SE2 SYNE2

2.46e-05180424fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

SPOCK2 LCK CDC42SE2 SYNE2

2.46e-0518042451a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPOCK2 GTF3C1 C12orf50 SYNE2

2.46e-05180424e53e9f3ebd48fb8237515e740ba5d9880ed6ade3
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

SPOCK2 LCK CDC42SE2 SYNE2

2.46e-0518042447036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPOCK2 GTF3C1 C12orf50 SYNE2

2.46e-051804249d18aa1044945fe6481ea3284037a777657fd837
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

SPOCK2 LCK CDC42SE2 SYNE2

2.52e-05181424534659cf754326c6a73c0daa30e9d610612a0292
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 LCK GTF3C1 SYNE2

2.57e-05182424f30e5a21b49f30b82e2b6f1fd2daefd805a40083
ToppCellControl-Lymphoid-T_Regulatory|Control / Disease state, Lineage and Cell class

SPOCK2 LCK CDC42SE2 SYNE2

2.57e-0518242431bb838cc2900f3c9da9f835d79d557a08abb928
ToppCellfacs-Spleen-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LANCL3 SPOCK2 IGF1R LCK

2.57e-05182424fbe5bdd642b86010dbef0a567b25c69c7335688f
ToppCellHealthy_donor-MAIT|Healthy_donor / disease group, cell group and cell class (v2)

SPOCK2 GTF3C1 BCAS2 SYNE2

2.57e-05182424ac7c83464487ecde3df6804a99551307bd768f21
ToppCellCOVID-19_Severe-Lymphoid_T/NK-MAIT|COVID-19_Severe / Disease group, lineage and cell class

SPOCK2 LCK GTF3C1 SYNE2

2.57e-0518242419045db5c726c06ec6e4feb4311633c8164ddb3c
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPOCK2 LCK GTF3C1 SYNE2

2.57e-051824241444cdc4522a70a40d697ccadf54cf26d327ade0
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

MYOM2 LCK GTF3C1 SYNE2

2.57e-0518242452baef8173df0a55307c375674a37c2488066738
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPOCK2 LCK GTF3C1 SYNE2

2.57e-05182424cccac9f85825f4e310b86e37ee6320769a670501
ToppCellfacs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LANCL3 SPOCK2 IGF1R LCK

2.57e-05182424da3e9093cba791c7c282eb044656046252a32789
ToppCellsevere_influenza-gd_T|severe_influenza / disease group, cell group and cell class (v2)

SPOCK2 MYOM2 LCK SYNE2

2.57e-05182424b6b44c90af3f0c0dddb2b171087865d8c15a3973
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPOCK2 LCK GTF3C1 SYNE2

2.57e-0518242449eced222e8f90c2b59bcc7d56b62c3e703fcce5
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

SPOCK2 MYOM2 GTF3C1 SYNE2

2.63e-05183424f593a89b0aa8fffdfa403769916facfd30358521
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPOCK2 LCK CDC42SE2 SYNE2

2.63e-05183424f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

AMFR TRANK1 RFX3 SOBP

2.63e-05183424dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 IGF1R LCK SYNE2

2.63e-05183424f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell|356C / Donor, Lineage, Cell class and subclass (all cells)

SPOCK2 LCK CDC42SE2 SYNE2

2.68e-051844245b4f18b26d03e8e5798cac70d124534749fc4cc0
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 SPOCK2 LCK SYNE2

2.74e-05185424406b52516b26e9fe2c9e768950af447ec7ad5f3e
ToppCellControl-Lymphocyte-T_NK-CD4_TEM|Control / Disease, Lineage and Cell Type

SPOCK2 LCK CDC42SE2 SYNE2

2.74e-051854248d6a089dcb4bfb0e74b6316fb7221688c1835e6e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 IGF1R CDC42SE2 SYNE2

2.74e-05185424847257d232b9993cad50c814fd4ffeef52385295
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 SPOCK2 LCK SYNE2

2.74e-05185424f2ebd099c8dfcfaca4298bcdd618c50701a9c2c8
ToppCellIPF-Lymphoid-T_Regulatory|IPF / Disease state, Lineage and Cell class

SPOCK2 LCK CDC42SE2 SYNE2

2.74e-05185424221cbd09d94cc0947d0e3c1aa14716d17cb2068d
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

SPOCK2 LCK CDC42SE2 SYNE2

2.74e-05185424846403edd4c8f646201d519055198fc38b7ffff9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 IGF1R LCK SYNE2

2.80e-05186424c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPOCK2 LCK GTF3C1 SYNE2

2.86e-05187424f1ba41f2ec703251a81c46e08d45e70210f298e7
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

N4BP2L2 LCK SYNE2

2.86e-0450283GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_UNASSIGNED_1
DrugEtodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A

AMFR IGF1R GTF3C1 SOBP TNPO2 PIEZO1

1.67e-061994267246_DN
Diseaseapolipoprotein A 1 measurement

MED24 AMFR PDE3A TRANK1 CDC42SE2 CXXC1 CD163

7.66e-05848377EFO_0004614
Diseasehemoglobin A1 measurement

PDE3A LCORL PIEZO1 SPTA1 SYNE2

4.56e-04520375EFO_0007629
Diseasecardioembolic stroke

IGF1R PHF20 SYNE2

1.26e-03170373EFO_1001976
Diseasemean platelet volume

N4BP2L2 TRANK1 PHF20 SSH1 SPTA1 SYNE2

1.56e-031020376EFO_0004584
Diseasehemolysis

PIEZO1 SPTA1

1.60e-0347372EFO_0009473
Diseasenon-high density lipoprotein cholesterol measurement

SSH1 LCORL SPTA1 CD163 SYNE2

1.87e-03713375EFO_0005689
Diseaseresponse to TNF antagonist

PDE3A RIMS1

2.10e-0354372EFO_0004653
Diseasebilirubin measurement

PDE3A REV3L PIEZO1 SPTA1

2.22e-03442374EFO_0004570
Diseasesexual dimorphism measurement

MED24 IGF1R TRANK1 LCK PHF20 LCORL

2.35e-031106376EFO_0021796

Protein segments in the cluster

PeptideGeneStartEntry
WVANDENCGICRMAF

ANAPC11

16

Q9NYG5
CFIETFKQWMENQDC

DISP1

851

Q96F81
NSVAWNTQCEDMLCF

IFT122

556

Q9HBG6
TDWSMDEKCSFCNLQ

LCORL

81

Q8N3X6
MSEFWLCFNCCIAEQ

CDC42SE2

1

Q9NRR3
QDACGSNSWNMVDVD

IGF1R

541

P08069
TDAETMNFIVNCSWD

MYLK3

716

Q32MK0
MNFIVNCSWDFDADT

MYLK3

721

Q32MK0
DWTNENDRLLVCQMC

PDE3A

931

Q14432
WQSVDFLMEQEQNCN

LANCL3

261

Q6ZV70
DDWMENIDVCENCHY

LCK

11

P06239
QFCNAGSNRFCEDWM

C17orf75

286

Q9HAS0
SNNEDKVVMWVCNLC

RIMS1

151

Q86UR5
INCFMIGCDNCNEWF

CXXC1

36

Q9P0U4
CNNGWSMEAVSVICN

CD163

76

Q86VB7
ENGFMIQCEECLCWQ

PHF20L1

691

A8MW92
EENDFMIQCEECQCW

PHF20

661

Q9BVI0
NCEAFQEQVWAEMCS

SYNE2

3191

Q8WXH0
EQASWVCQCDDNMVQ

RFX3

536

P48380
CFDTSNEDDCNWMML

PRDM15

471

P57071
GVSMWCELEQENFFN

HUS1

51

O60921
TQFVQWFMEECVDCL

MED24

921

O75448
TAWQECVNNSMAQLE

BCAS2

101

O75934
SEQSCINEWNAMQDL

SSH1

216

Q8WYL5
VNNDDCAICWDSMQA

AMFR

336

Q9UKV5
MVWFCNSADCQFSVF

CLDN34

1

H7C241
MEMQQNCSISCFWET

C12orf50

1

Q8NA57
VQECMAQHQDWRQCQ

COA4

41

Q9NYJ1
MGEFFWATANCTVQC

TECTA

661

O75443
NWTYQECNNCSEEMF

SCN2B

66

O60939
ICCCMSEMNEWDTQN

WDFY3

3216

Q8IZQ1
NSIMDSFCVQQAEDC

REV3L

1756

O60673
EDDVSNVQIMCAWCQ

SOBP

141

A7XYQ1
VCNNATWAIGEICMQ

TNPO2

721

O14787
AVAQCFLAENDWEME

TDP2

41

O95551
ELQMFQGNCDQVESW

SPTA1

1396

P02549
ACVFVEQMQTGFCWV

PIEZO1

1236

Q92508
CLQDFDNMTWEIECT

TRANK1

781

O15050
MQDVENYWFDLQCVC

GTF3C1

1031

Q12789
AMAAFDLACSQCQLW

ZFYVE26

971

Q68DK2
MQCDQSSGDCWCVDQ

SPOCK2

346

Q92563
WNCMTFDQNNEYTDC

N4BP2L2

326

Q92802
DCQEMTDASQFTWCK

MYOM2

931

P54296