Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

NID2 EFEMP2 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1 FBN3

3.67e-07188989GO:0005201
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

EFEMP2 FBN1 FBN2

2.44e-0512983GO:0030023
GeneOntologyMolecularFunctionsulfur compound binding

ADAMTS3 EFEMP2 CXCL13 CCN6 ZCCHC4 CCN4 NELL1 FBN1 DMBT1

3.02e-05323989GO:1901681
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

EFEMP2 FBN1 FBN2

4.01e-0514983GO:0097493
GeneOntologyMolecularFunctionheparin binding

ADAMTS3 EFEMP2 CXCL13 CCN6 CCN4 NELL1 FBN1

4.50e-05192987GO:0008201
GeneOntologyMolecularFunctionglycosaminoglycan binding

ADAMTS3 EFEMP2 CXCL13 CCN6 CCN4 NELL1 FBN1 DMBT1

5.26e-05268988GO:0005539
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A7 SLC17A6

7.13e-053982GO:0140788
GeneOntologyMolecularFunctionstructural molecule activity

NID2 KRT81 KRT83 KRT86 EFEMP2 EVPL KRTAP16-1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1 FBN3

1.12e-048919814GO:0005198
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A7 SLC17A6

2.36e-045982GO:0022810
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

PDGFRB ACVR1B LTBP1 EPHB1

8.15e-0485984GO:0019199
GeneOntologyMolecularFunctionpore-forming activity

DEFA1 DEFA3

1.05e-0310982GO:0140911
GeneOntologyMolecularFunctionuniporter activity

SLC17A7 SLC17A6

1.05e-0310982GO:0015292
GeneOntologyMolecularFunctioncalcium ion binding

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

1.11e-037499811GO:0005509
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT81 KRT83 KRT86

1.23e-0343983GO:0030280
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A7 SLC17A6

1.52e-0312982GO:0005436
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

MECOM PRDM2

1.80e-0313982GO:0046974
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC17A7 SLC17A6

2.09e-0314982GO:0015386
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC17A7 SLC17A6

2.40e-0315982GO:0005313
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2 LTBP1

3.90e-074963GO:0035583
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2 LTBP1

5.38e-068963GO:0071694
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2 LTBP1

1.57e-0511963GO:0035581
GeneOntologyBiologicalProcessdefense response to bacterium

DEFB104A CXCL13 RNASE12 OAS1 EVPL MUC5B DEFB103A DEFA1 DEFA3 DMBT1

1.91e-054059610GO:0042742
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2 LTBP1

2.70e-0513963GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2 LTBP1

2.70e-0513963GO:1900116
GeneOntologyBiologicalProcessdefense response to Gram-positive bacterium

DEFB104A RNASE12 DEFB103A DEFA1 DEFA3 DMBT1

7.24e-05150966GO:0050830
GeneOntologyCellularComponentmicrofibril

EFEMP2 MFAP2 FBN1 FBN2 LTBP1 FBN3

1.52e-1113986GO:0001527
GeneOntologyCellularComponentextracellular matrix

NID2 ADAMTS3 ADAMTS2 EFEMP2 MUC5B DEFA1 CCN6 CCN4 MFAP2 FBN1 FBN2 HMCN1 CCBE1 LTBP1 DMBT1 FBN3

6.41e-086569816GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NID2 ADAMTS3 ADAMTS2 EFEMP2 MUC5B DEFA1 CCN6 CCN4 MFAP2 FBN1 FBN2 HMCN1 CCBE1 LTBP1 DMBT1 FBN3

6.68e-086589816GO:0030312
GeneOntologyCellularComponentkeratin filament

KRTAP9-4 KRT81 KRT83 KRT86 KRTAP16-1 KRTAP9-2 KRTAP9-9

3.65e-0797987GO:0045095
GeneOntologyCellularComponentintermediate filament

KRTAP9-4 KRT81 KRT83 KRT86 EVPL KRTAP16-1 KRTAP9-2 KRTAP9-9

1.16e-05227988GO:0005882
GeneOntologyCellularComponentsupramolecular fiber

KRTAP9-4 KRT81 KRT83 KRT86 EFEMP2 OBSL1 EVPL KRTAP16-1 MFAP2 FBN1 FBN2 SQSTM1 KRTAP9-2 KRTAP9-9 LTBP1 CKAP2 FBN3

3.15e-0511799817GO:0099512
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRTAP9-4 KRT81 KRT83 KRT86 EVPL KRTAP16-1 KRTAP9-2 KRTAP9-9

3.34e-05263988GO:0045111
GeneOntologyCellularComponentsupramolecular polymer

KRTAP9-4 KRT81 KRT83 KRT86 EFEMP2 OBSL1 EVPL KRTAP16-1 MFAP2 FBN1 FBN2 SQSTM1 KRTAP9-2 KRTAP9-9 LTBP1 CKAP2 FBN3

3.43e-0511879817GO:0099081
GeneOntologyCellularComponentcollagen-containing extracellular matrix

NID2 ADAMTS3 ADAMTS2 EFEMP2 DEFA1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1

3.84e-055309811GO:0062023
GeneOntologyCellularComponentGolgi lumen

MUC5B DEFB103A DEFA1 DEFA3

1.73e-03109984GO:0005796
HumanPhenoPerifollicular hyperkeratosis

KRT81 KRT83 KRT86

1.40e-064373HP:0007468
HumanPhenoAbnormal perifollicular morphology

KRT81 KRT83 KRT86

6.95e-066373HP:0031285
MousePhenoabnormal tendon collagen fibril morphology

ADAMTS2 EFEMP2 MECOM

5.32e-067763MP:0011643
MousePhenoabnormal tendon morphology

ADAMTS2 EFEMP2 MECOM FBN1

2.27e-0531764MP:0005503
MousePhenoabnormal viscerocranium morphology

ZEB1 KRTAP9-4 ADAMTS2 PDGFRB MECOM OAS1 NELL1 FBN1 FBN2 KRTAP9-2 KRTAP9-9 LTBP1

7.85e-055937612MP:0005274
MousePhenoabnormal cranium morphology

ZEB1 KRTAP9-4 ADAMTS3 ADAMTS2 PDGFRB MECOM OAS1 NELL1 NEK1 FBN1 FBN2 KRTAP9-2 KRTAP9-9 LTBP1

1.07e-048137614MP:0000438
MousePhenoabnormal endocrine gland morphology

ZEB1 KRTAP9-4 ACD ADAMTS3 PDGFRB OAS1 PLPPR5 ACVR1B PRDM2 NELL1 SIDT2 FBN1 FBXO9 KRTAP9-2 DIP2C KRTAP9-9 RNF208

1.09e-0411447617MP:0013560
MousePhenoabnormal craniofacial bone morphology

ZEB1 KRTAP9-4 ADAMTS3 ADAMTS2 PDGFRB MECOM OAS1 NELL1 NEK1 FBN1 FBN2 KRTAP9-2 KRTAP9-9 LTBP1

1.28e-048277614MP:0002116
MousePhenoabnormal jaw morphology

ZEB1 KRTAP9-4 ADAMTS2 PDGFRB MECOM OAS1 FBN1 FBN2 KRTAP9-2 KRTAP9-9 LTBP1

1.29e-045307611MP:0000454
MousePhenoabnormal distal visceral endoderm morphology

ACVR1B BPTF

1.74e-044762MP:0010126
MousePhenoeffusion

ZEB1 ADAMTS3 DLL4 MECOM MUC5B FBN1

1.75e-04152766MP:0021205
MousePhenoabnormal aorta morphology

ADAMTS3 PDGFRB DLL4 EFEMP2 MECOM FBN1 LTBP1

2.17e-04225767MP:0000272
MousePhenoabnormal ascending aorta morphology

EFEMP2 FBN1 LTBP1

2.21e-0422763MP:0009867
MousePhenosmall adrenal glands

ACD ACVR1B NELL1 FBXO9

2.56e-0457764MP:0002768
MousePhenoabsent lymphatic vessels

ADAMTS3 CCBE1

2.89e-045762MP:0010194
MousePhenoascending aorta aneurysm

EFEMP2 FBN1

2.89e-045762MP:0010661
MousePhenoabnormal craniofacial morphology

ZEB1 KRTAP9-4 ACD ADAMTS3 ADAMTS2 PDGFRB MECOM OAS1 ZEB2 NELL1 NEK1 FBN1 FBN2 CCBE1 KRTAP9-2 UHRF1 KRTAP9-9 LTBP1

3.16e-0413727618MP:0000428
MousePhenocraniofacial phenotype

ZEB1 KRTAP9-4 ACD ADAMTS3 ADAMTS2 PDGFRB MECOM OAS1 ZEB2 NELL1 NEK1 FBN1 FBN2 CCBE1 KRTAP9-2 UHRF1 KRTAP9-9 LTBP1

3.16e-0413727618MP:0005382
MousePhenoabnormal cutaneous collagen fibril morphology

ADAMTS2 EFEMP2 FBN1

4.11e-0427763MP:0008438
MousePhenothoracic aorta aneurysm

EFEMP2 FBN1

4.31e-046762MP:0010658
DomainGrowth_fac_rcpt_

NID2 DLL4 KRT83 EFEMP2 CCN6 CCN4 NELL1 FBN1 FBN2 SCUBE2 HMCN1 LTBP1 FBN3 EPHB1

5.91e-141569614IPR009030
DomaincEGF

NID2 EFEMP2 FBN1 FBN2 SCUBE2 HMCN1 LTBP1 FBN3

5.24e-1326968IPR026823
DomaincEGF

NID2 EFEMP2 FBN1 FBN2 SCUBE2 HMCN1 LTBP1 FBN3

5.24e-1326968PF12662
DomainASX_HYDROXYL

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

3.57e-121009611PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

6.84e-121069611IPR000152
DomainEGF_CA

NID2 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

2.04e-11869610PF07645
DomainEGF_CA

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

3.23e-111229611SM00179
DomainEGF-like_Ca-bd_dom

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

3.86e-111249611IPR001881
DomainEGF_Ca-bd_CS

NID2 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

6.93e-11979610IPR018097
DomainEGF_CA

NID2 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

8.52e-11999610PS01187
DomainEGF-like_CS

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3 EPHB1

9.51e-092619612IPR013032
DomainEGF_2

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3 EPHB1

1.13e-082659612PS01186
DomainTB

FBN1 FBN2 LTBP1 FBN3

2.27e-087964PF00683
DomainEGF_3

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

3.41e-082359611PS50026
DomainEGF

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

3.41e-082359611SM00181
Domain-

FBN1 FBN2 LTBP1 FBN3

4.52e-0889643.90.290.10
DomainEGF-like_dom

NID2 DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

6.16e-082499611IPR000742
DomainTB

FBN1 FBN2 LTBP1 FBN3

8.10e-089964PS51364
DomainTB_dom

FBN1 FBN2 LTBP1 FBN3

8.10e-089964IPR017878
DomainFBN

FBN1 FBN2 FBN3

1.32e-073963IPR011398
DomainEGF_1

DLL4 EFEMP2 NELL1 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 FBN3

7.60e-072559610PS00022
DomainTSP_1

ADAMTS3 ADAMTS2 CCN6 CCN4 HMCN1

1.79e-0563965PF00090
DomainTSP1

ADAMTS3 ADAMTS2 CCN6 CCN4 HMCN1

2.09e-0565965SM00209
DomainTSP1_rpt

ADAMTS3 ADAMTS2 CCN6 CCN4 HMCN1

2.09e-0565965IPR000884
DomainTSP1

ADAMTS3 ADAMTS2 CCN6 CCN4 HMCN1

2.09e-0565965PS50092
DomainEGF_3

NID2 NELL1 SCUBE2

2.80e-0512963PF12947
DomainEGF_dom

NID2 NELL1 SCUBE2

2.80e-0512963IPR024731
DomainKeratin_B2_2

KRTAP9-4 KRTAP16-1 KRTAP9-2 KRTAP9-9

4.70e-0539964PF13885
DomainEGF

NID2 DLL4 SCUBE2 HMCN1 LTBP1 FBN3

4.72e-05126966PF00008
DomainGlyco_hormone_CN

MUC5B CCN6 CCN4

5.73e-0515963IPR006208
DomainCys_knot

MUC5B CCN6 CCN4

5.73e-0515963PF00007
DomainG2F

NID2 HMCN1

7.82e-053962SM00682
DomainCTCK_1

MUC5B CCN6 CCN4

1.02e-0418963PS01185
DomainGFP

NID2 HMCN1

1.56e-044962IPR009017
DomainG2F

NID2 HMCN1

1.56e-044962PF07474
DomainG2_nidogen/fibulin_G2F

NID2 HMCN1

1.56e-044962IPR006605
DomainNIDOGEN_G2

NID2 HMCN1

1.56e-044962PS50993
DomainCT

MUC5B CCN6 CCN4

1.89e-0422963SM00041
DomainKAP

KRTAP9-4 KRTAP16-1 KRTAP9-2 KRTAP9-9

2.25e-0458964IPR002494
DomainKeratin_2_head

KRT81 KRT83 KRT86

2.46e-0424963IPR032444
DomainKeratin_2_head

KRT81 KRT83 KRT86

2.46e-0424963PF16208
DomainDefensin_propep

DEFA1 DEFA3

2.59e-045962PF00879
DomainAlpha-defensin

DEFA1 DEFA3

2.59e-045962IPR006081
DomainDefensin_1

DEFA1 DEFA3

2.59e-045962PF00323
DomainAlpha-defensin_pro

DEFA1 DEFA3

2.59e-045962IPR016327
DomainDEFENSIN

DEFA1 DEFA3

2.59e-045962PS00269
DomainDefensin_propep

DEFA1 DEFA3

2.59e-045962IPR002366
DomainIGFBP_CNN

CCN6 CCN4

2.59e-045962IPR012395
DomainCys_knot_C

MUC5B CCN6 CCN4

2.79e-0425963IPR006207
DomainCTCK_2

MUC5B CCN6 CCN4

2.79e-0425963PS01225
DomainKeratin_II

KRT81 KRT83 KRT86

3.14e-0426963IPR003054
DomainVWC

MUC5B CCN4 NELL1

3.93e-0428963PF00093
DomainDi19_Zn_binding_dom

ZEB1 ZEB2

5.40e-047962IPR008598
Domainzf-Di19

ZEB1 ZEB2

5.40e-047962PF05605
DomainDefensin_beta/alpha

DEFA1 DEFA3

7.17e-048962IPR006080
DomainDEFSN

DEFA1 DEFA3

7.17e-048962SM00048
DomainVWFC_1

MUC5B CCN4 NELL1

8.31e-0436963PS01208
DomainVWC

MUC5B CCN4 NELL1

9.74e-0438963SM00214
DomainVWFC_2

MUC5B CCN4 NELL1

9.74e-0438963PS50184
DomainKeratin_B2

KRTAP9-4 KRTAP9-2 KRTAP9-9

1.13e-0340963PF01500
DomainVWF_dom

MUC5B CCN4 NELL1

1.31e-0342963IPR001007
Domain-

NID2 HMCN1

1.40e-03119622.40.155.10
DomainGFP-like

NID2 HMCN1

1.40e-0311962IPR023413
DomainInsulin_GF-bd_Cys-rich_CS

CCN6 CCN4

1.40e-0311962IPR017891
DomainIGFBP_N_1

CCN6 CCN4

1.67e-0312962PS00222
DomainuDENN

DENND2A DENND2B

2.29e-0314962SM00800
DomainuDENN

DENND2A DENND2B

2.63e-0315962PF03456
DomainUDENN

DENND2A DENND2B

2.99e-0316962PS50946
DomainDDENN

DENND2A DENND2B

2.99e-0316962PS50947
DomainDENN

DENND2A DENND2B

2.99e-0316962SM00799
DomaindDENN

DENND2A DENND2B

2.99e-0316962SM00801
DomainDENN

DENND2A DENND2B

2.99e-0316962PF02141
DomaindDENN_dom

DENND2A DENND2B

2.99e-0316962IPR005112
DomainuDENN_dom

DENND2A DENND2B

2.99e-0316962IPR005113
DomaindDENN

DENND2A DENND2B

2.99e-0316962PF03455
DomainDENN

DENND2A DENND2B

2.99e-0316962PS50211
DomainDENN_dom

DENND2A DENND2B

2.99e-0316962IPR001194
DomainIB

CCN6 CCN4

3.79e-0318962SM00121
DomainIntermediate_filament_CS

KRT81 KRT83 KRT86

4.18e-0363963IPR018039
DomainVWC_out

MUC5B NELL1

4.22e-0319962SM00215
DomainPLAC

ADAMTS3 ADAMTS2

4.22e-0319962PS50900
DomainPLAC

ADAMTS3 ADAMTS2

4.22e-0319962IPR010909
DomainIGFBP-like

CCN6 CCN4

4.68e-0320962IPR000867
DomainIGFBP

CCN6 CCN4

4.68e-0320962PF00219
DomainIGFBP_N_2

CCN6 CCN4

4.68e-0320962PS51323
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

EFEMP2 MFAP2 FBN1 FBN2 LTBP1 FBN3

4.43e-0837776M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

EFEMP2 MFAP2 FBN1 FBN2 LTBP1 FBN3

1.30e-0744776M26969
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

EFEMP2 MFAP2 FBN1 FBN2 LTBP1

7.65e-0732775MM14854
PathwayREACTOME_KERATINIZATION

KRTAP9-4 KRT81 KRT83 KRT86 EVPL KRTAP16-1 KRTAP9-2 KRTAP9-9

1.79e-06153778MM15343
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

EFEMP2 MFAP2 FBN1 FBN2 LTBP1

2.12e-0639775MM14601
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2 LTBP1 FBN3

9.54e-0625774M39713
PathwayREACTOME_KERATINIZATION

KRTAP9-4 KRT81 KRT83 KRT86 EVPL KRTAP16-1 KRTAP9-2 KRTAP9-9

2.34e-05217778M27640
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 ADAMTS3 ADAMTS2 EFEMP2 MFAP2 FBN1 FBN2 LTBP1 FBN3

3.60e-05300779M610
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 ADAMTS3 ADAMTS2 EFEMP2 MFAP2 FBN1 FBN2 LTBP1

7.99e-05258778MM14572
PathwayREACTOME_DEFENSINS

DEFB104A DEFB103A DEFA1 DEFA3

1.97e-0453774M557
PathwayREACTOME_DEFENSINS

DEFB103A DEFA1 DEFA3

6.31e-0431773MM14568
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP1

8.07e-048772M47850
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT83 KRT86

2.17e-0839831372089
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT83 KRT86

2.17e-0839831712823
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT83 KRT86

2.17e-08398325557232
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2 LTBP1

8.66e-08498312429738
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

MFAP2 FBN1 FBN2

8.66e-08498325406291
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2 FBN3

8.66e-08498325034023
Pubmed

Keratins of the human hair follicle.

KRT81 KRT83 KRT86

8.66e-08498315797458
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

NID2 EFEMP2 MFAP2 FBN1 FBN2 LTBP1

1.68e-078698628327460
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

EFEMP2 FBN1 FBN2

2.16e-07598317255108
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 FBN2 LTBP1

2.16e-07598334411563
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

MFAP2 FBN1 FBN2

2.16e-07598323493297
Pubmed

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

EFEMP2 FBN1 LTBP1

4.31e-07698319349279
Pubmed

Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.

PDGFRB FBN1 FBN2

4.31e-0769837873879
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

NID2 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1

6.81e-0717598728071719
Pubmed

An ultra-high sulfur keratin gene is expressed specifically during hair growth.

KRTAP9-4 KRTAP9-2 KRTAP9-9

1.20e-0689832465353
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

EFEMP2 FBN1 FBN2 LTBP1

1.54e-063098432882513
Pubmed

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

MFAP2 FBN1 FBN2 LTBP1

1.76e-063198425762570
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FBN2 LTBP1

1.80e-06998338844137
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS3 ADAMTS2 CCN6 CCN4 HMCN1

2.37e-067598520637190
Pubmed

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.

KRTAP9-4 KRTAP16-1 KRTAP9-2 KRTAP9-9

3.64e-063798411279113
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT81 KRT83 KRT86

4.69e-061298310692104
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

MFAP2 FBN1 FBN2

4.69e-061298326405179
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

7.86e-06298212399449
Pubmed

Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro.

DEFA1 DEFA3

7.86e-06298212871849
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

7.86e-06298221851253
Pubmed

Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter.

SLC17A7 SLC17A6

7.86e-06298210820226
Pubmed

Disruption of VGLUT1 in Cholinergic Medial Habenula Projections Increases Nicotine Self-Administration.

SLC17A7 SLC17A6

7.86e-06298234876472
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

7.86e-06298212429739
Pubmed

alpha-Defensins 1, 2, and 3 are expressed by granulocytes in lymphoid tissues of HIV-1-seropositive and -seronegative individuals.

DEFA1 DEFA3

7.86e-06298216837860
Pubmed

ZEBs: Novel Players in Immune Cell Development and Function.

ZEB1 ZEB2

7.86e-06298230956067
Pubmed

Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.

ZEB1 ZEB2

7.86e-06298228416756
Pubmed

Interplay between VGLUT isoforms and endophilin A1 regulates neurotransmitter release and short-term plasticity.

SLC17A7 SLC17A6

7.86e-06298221435559
Pubmed

Vesicular glutamate transporters VGLUT1 and VGLUT2 in the developing mouse barrel cortex.

SLC17A7 SLC17A6

7.86e-06298217289331
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

7.86e-06298230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

7.86e-06298221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

7.86e-06298215131124
Pubmed

Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites.

SLC17A7 SLC17A6

7.86e-06298215118123
Pubmed

Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development.

ZEB1 ZEB2

7.86e-06298212609600
Pubmed

Expression of miRNAs and ZEB1 and ZEB2 correlates with histopathological grade in papillary urothelial tumors of the urinary bladder.

ZEB1 ZEB2

7.86e-06298224306957
Pubmed

Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse.

SLC17A7 SLC17A6

7.86e-06298218181146
Pubmed

Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis.

DEFA1 DEFA3

7.86e-06298215208269
Pubmed

Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.

ZEB1 ZEB2

7.86e-06298220375168
Pubmed

Prognostic Significance of Zinc Finger E-Box-Binding Homeobox Family in Glioblastoma.

ZEB1 ZEB2

7.86e-06298229476046
Pubmed

Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer.

ZEB1 ZEB2

7.86e-06298222213144
Pubmed

Plasma human neutrophil proteins-1, -2, and -3 levels in patients with bladder cancer.

DEFA1 DEFA3

7.86e-06298223011762
Pubmed

Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development.

ZEB1 ZEB2

7.86e-06298216957952
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

7.86e-06298212524050
Pubmed

Human Neutrophil Peptides 1-3--early markers in development of colorectal adenomas and carcinomas.

DEFA1 DEFA3

7.86e-06298218957723
Pubmed

Expression of α-defensin 1-3 in T cells from severe cutaneous drug-induced hypersensitivity reactions.

DEFA1 DEFA3

7.86e-06298220880148
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

7.86e-06298220404337
Pubmed

The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.

FBN1 LTBP1

7.86e-06298228669633
Pubmed

A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.

KRT83 KRT86

7.86e-06298215744029
Pubmed

Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.

DEFA1 DEFA3

7.86e-06298220195543
Pubmed

Characterization of metabolic health in mouse models of fibrillin-1 perturbation.

MFAP2 FBN1

7.86e-06298226902431
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

7.86e-0629828791520
Pubmed

Transiently increased colocalization of vesicular glutamate transporters 1 and 2 at single axon terminals during postnatal development of mouse neocortex: a quantitative analysis with correlation coefficient.

SLC17A7 SLC17A6

7.86e-06298218028110
Pubmed

The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.

ZEB1 ZEB2

7.86e-06298237819755
Pubmed

Salivary levels of HNP 1-3 are related to oral ulcer activity in Behçet's disease.

DEFA1 DEFA3

7.86e-06298222861387
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

7.86e-0629828120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

7.86e-06298235419902
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

7.86e-0629828307578
Pubmed

Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease.

SLC17A7 SLC17A6

7.86e-06298217531353
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

7.86e-06298210504303
Pubmed

The putative role of human peritoneal adipocytes in the fight against bacteria: synthesis of the antimicrobial active peptide DEFA1-3.

DEFA1 DEFA3

7.86e-06298220424487
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

7.86e-06298215221638
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

7.86e-0629827744963
Pubmed

Defensins: antimicrobial and cytotoxic peptides of mammalian cells.

DEFA1 DEFA3

7.86e-0629828476558
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

7.86e-06298226408953
Pubmed

Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer.

ZEB1 ZEB2

7.86e-06298222892238
Pubmed

Detection of colorectal disease by stool defensin assay: an exploratory study.

DEFA1 DEFA3

7.86e-06298217531545
Pubmed

Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum.

SLC17A7 SLC17A6

7.86e-06298221800314
Pubmed

Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult.

SLC17A7 SLC17A6

7.86e-06298226705736
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

7.86e-06298218006876
Pubmed

The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery.

ZEB1 ZEB2

7.86e-06298225082886
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

7.86e-06298224833718
Pubmed

Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells.

CCN6 CCN4

7.86e-06298215650268
Pubmed

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway.

ZEB1 ZEB2

7.86e-06298220025777
Pubmed

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

ZEB1 ZEB2

7.86e-06298220424117
Pubmed

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients.

DEFA1 DEFA3

7.86e-06298229950924
Pubmed

Increased levels of human neutrophil alpha-defensins in chronic venous leg ulcers.

DEFA1 DEFA3

7.86e-06298218472248
Pubmed

Identification of a major microfibril-associated glycoprotein-1-binding domain in fibrillin-2.

MFAP2 FBN2

7.86e-06298215044481
Pubmed

Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization.

DEFA1 DEFA3

7.86e-0629822006422
Pubmed

Localization of human neutrophil peptide (HNP) and its messenger RNA in neutrophil series.

DEFA1 DEFA3

7.86e-0629828080882
Pubmed

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.

ZEB1 ZEB2

7.86e-06298221747944
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

7.86e-06298224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

7.86e-06298220529844
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

7.86e-06298225524144
Pubmed

Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1.

MFAP2 FBN1

7.86e-06298211481325
Pubmed

Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia.

SLC17A7 SLC17A6

7.86e-06298218155679
Pubmed

The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3.

DEFA1 DEFA3

7.86e-06298218474654
Pubmed

A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.

KRT81 KRT86

7.86e-0629829665406
Pubmed

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

DEFA1 DEFA3

7.86e-06298219864642
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

7.86e-06298223133647
Pubmed

The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.

ZEB1 ZEB2

7.86e-06298237948583
Pubmed

Multidrug-resistant tuberculosis is associated with low plasma concentrations of human neutrophil peptides 1-3.

DEFA1 DEFA3

7.86e-06298221333105
Pubmed

Increased levels of alpha-defensin (-1, -2 and -3) in type 1 diabetic patients with nephropathy.

DEFA1 DEFA3

7.86e-06298218003664
Pubmed

CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer.

ZEB1 CCN6

7.86e-06298221525039
Pubmed

Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity.

SLC17A7 SLC17A6

7.86e-06298219171494
Pubmed

The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.

ZEB1 ZEB2

7.86e-06298228133913
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

7.86e-06298216407178
InteractionHOXA1 interactions

KRTAP9-4 KRT81 KRT83 EFEMP2 CCN4 NELL1 MFAP2 FBN1 KRTAP9-2 LTBP1 RNF208

9.30e-073569511int:HOXA1
InteractionELN interactions

NID2 MFAP2 FBN1 FBN2

1.01e-0529954int:ELN
InteractionMFAP2 interactions

MFAP2 FBN1 FBN2

2.16e-0512953int:MFAP2
Cytoband12q13

KRT81 KRT83 KRT86 ACVR1B

1.70e-057198412q13
Cytoband17q12-q21

KRTAP9-4 KRTAP9-2 COASY

4.47e-053298317q12-q21
Cytoband8p23.1

DEFB104A DEFB103A DEFA1 DEFA3

3.44e-041549848p23.1
Cytoband17q21.2

KRTAP16-1 KRTAP9-9 HOXB13

4.65e-047098317q21.2
CytobandEnsembl 112 genes in cytogenetic band chr17q21

KRTAP9-4 KRTAP16-1 KRTAP9-2 KRTAP9-9 COASY HOXB13

5.49e-04473986chr17q21
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR5P3 MUC5B DENND2B NELL1 SCUBE2 CHRNA10

1.36e-03564986chr11p15
CytobandEnsembl 112 genes in cytogenetic band chr8p23

DEFB104A DEFB103A DEFA1 DEFA3

1.63e-03234984chr8p23
CytobandEnsembl 112 genes in cytogenetic band chr12q13

INHBC KRT81 KRT83 KRT86 ACVR1B

2.18e-03423985chr12q13
Cytoband3q25.1

ANKUB1 MED12L

2.28e-03339823q25.1
CytobandXq25

DCAF12L2 DCAF12L1

3.50e-0341982Xq25
CytobandEnsembl 112 genes in cytogenetic band chrXq25

DCAF12L2 DCAF12L1

4.77e-0348982chrXq25
GeneFamilyKeratins, type II

KRT81 KRT83 KRT86

1.46e-0427693609
GeneFamilyCYR61/CTGF/NOV matricellular proteins

CCN6 CCN4

2.13e-0466921046
GeneFamilyFibulins

EFEMP2 HMCN1

3.96e-048692556
GeneFamilyKeratin associated proteins

KRTAP9-4 KRTAP16-1 KRTAP9-2 KRTAP9-9

7.99e-04109694619
GeneFamilyDefensins, alpha

DEFA1 DEFA3

9.24e-0412692502
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB1 ZEB2

1.46e-0315692529
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

MECOM PRDM2

1.88e-03176921197
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS3 ADAMTS2

2.35e-031969250
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2A DENND2B

4.07e-0325692504
GeneFamilyPHD finger proteins

PHF8 BPTF UHRF1

4.93e-039069388
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

MECOM PRDM2

7.44e-0334692487
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 EFEMP2 CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1 FBN3

7.86e-121969612M3008
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 EFEMP2 CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1

1.19e-101919611MM17059
CoexpressionNABA_CORE_MATRISOME

NID2 EFEMP2 CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1 FBN3

4.00e-102759612M5884
CoexpressionNABA_CORE_MATRISOME

NID2 EFEMP2 CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 HMCN1 LTBP1 DMBT1

4.60e-092709611MM17057
CoexpressionNABA_MATRISOME

NID2 ADAMTS3 ADAMTS2 INHBC EFEMP2 CXCL13 MUC5B CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 DMBT1 FBN3

5.00e-0910269619M5889
CoexpressionNABA_MATRISOME

NID2 ADAMTS3 ADAMTS2 INHBC EFEMP2 CXCL13 MUC5B CCN6 CCN4 NELL1 MFAP2 FBN1 FBN2 SCUBE2 HMCN1 CCBE1 LTBP1 DMBT1

2.35e-0810089618MM17056
CoexpressionSCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP

NID2 ZEB1 PDGFRB EFEMP2 ZEB2 CCN4 MFAP2 FBN1 FBN2

5.96e-06352969M17471
CoexpressionROVERSI_GLIOMA_LOH_REGIONS

ADAMTS3 PRDM2 NELL1 SLC17A6

2.24e-0545964M6712
CoexpressionZHONG_PFC_C3_ASTROCYTE

ACD ZEB2 PRDM2 TAF6L BPTF CCBE1 DIP2C FBN3

9.31e-05389968M39102
CoexpressionGSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN

EFEMP2 OBSL1 MECOM DENND2B TAF6L MFAP2

9.60e-05200966M5153
CoexpressionNOUZOVA_METHYLATED_IN_APL

KLF11 VPS8 HOXB13 ZNF304

1.02e-0466964M16097
CoexpressionMARTINEZ_RB1_TARGETS_DN

KRTAP9-4 KRT81 KRT83 KRT86 RXYLT1 FBN2 KRTAP9-2 KRTAP9-9 LTBP1 HNRNPLL

1.06e-046309610MM1038
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRTAP9-4 KRT81 KRT83 KRT86 KRTAP9-2 KRTAP9-9

1.07e-04204966MM966
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 PDGFRB EFEMP2 ZEB2 CCN4 MFAP2 FBN1 FBN2 HMCN1 UHRF1

1.01e-073109211gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

DENND2A PDGFRB ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

2.89e-07207929gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 SZT2 PDGFRB OBSL1 DENND2B ZEB2 NELL1 MFAP2 FBN1 FBN2 HMCN1 DIP2C LTBP1

3.51e-067409214gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

ADAMTS2 CCN4 NEK1 FBN1 FBN2 DCAF12L1 TMLHE SOCS5 ARAP1

4.45e-06288929gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 PDGFRB EFEMP2 OBSL1 PHF8 DENND2B ZEB2 CCN4 MFAP2 FBN1 FBN2 HMCN1 UHRF1

5.37e-067689214gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

DENND2A SZT2 PDGFRB OBSL1 RNASE12 PHF8 DENND2B ZEB2 NELL1 MFAP2 FBN1 FBN2 HMCN1 LTBP1

6.70e-067839214gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

ZEB1 ADAMTS3 ADAMTS2 PDGFRB OBSL1 PHF8 DENND2B ZEB2 CCN4 MFAP2 FBN1 HMCN1 UHRF1 CKAP2

7.74e-067939214gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

DENND2A ZEB1 ADAMTS3 ADAMTS2 PDGFRB OBSL1 DENND2B NELL1 MFAP2 FBN1 FBN2 DCAF12L1 HMCN1 CCBE1

8.19e-067979214gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

ZEB1 ADAMTS3 ADAMTS2 PDGFRB MFAP2 FBN1 HMCN1

8.53e-06168927gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000

NID2 KLF11 ADAMTS2 PLPPR5 CCN4 DCAF12L1 CKAP2 ARAP1 EPHB1

1.12e-05323929gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

DENND2A PDGFRB ZEB2 MFAP2 FBN1 HMCN1 CCBE1 UHRF1 LTBP1

1.24e-05327929gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

DENND2A PDGFRB DENND2B ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

1.34e-054189210gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 PDGFRB EFEMP2 ZEB2 MFAP2 FBN1 HMCN1 UHRF1

1.53e-05336929gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

DENND2A PDGFRB ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

1.57e-05337929gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

ZEB1 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 HMCN1

1.96e-05191927gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 PDGFRB ZEB2 MFAP2 FBN1 FBN2 HMCN1

1.99e-05265928gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#2_top-relative-expression-ranked_500

NID2 ADAMTS2 PLPPR5 CCN4 DCAF12L1 EPHB1

2.08e-05129926gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k2
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

ADAMTS2 PDGFRB ZEB2 MFAP2 FBN1 HMCN1

2.17e-05130926gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

ADAMTS3 PDGFRB ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

2.31e-05354929gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

ADAMTS3 ADAMTS2 PDGFRB EFEMP2 OBSL1 PHF8 DENND2B ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1

2.81e-057739213gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

ADAMTS3 PDGFRB OBSL1 PHF8 DENND2B ZEB2 FBN1 HMCN1 UHRF1

2.88e-05364929gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

ZEB1 ADAMTS2 PDGFRB EFEMP2 DENND2B ZEB2 CCN4 MFAP2 FBN1 FBN2 HMCN1 CCBE1 CKAP2

2.96e-057779213gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

ADAMTS2 PDGFRB OBSL1 DENND2B ZEB2 MFAP2 FBN1 HMCN1 UHRF1

3.48e-05373929gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

DENND2A PDGFRB FBN1 FBN2 HMCN1 LTBP1

4.18e-05146926gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

DENND2A SZT2 PDGFRB DENND2B NELL1 FBN1 FBN2 HMCN1 LTBP1

4.73e-05388929gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

ADAMTS2 PDGFRB ZEB2 MFAP2 FBN1 HMCN1

6.05e-05156926gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500

NID2 KLF11 ADAMTS3 ADAMTS2 PLPPR5 CCN4 DCAF12L1 CKAP2 EPHB1

8.68e-05420929gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

PDGFRB ZEB2 MFAP2 FBN1 HMCN1

1.03e-04107925gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

ADAMTS3 ADAMTS2 PDGFRB ZEB2 MFAP2 FBN1 FBN2 HMCN1

1.58e-04356928gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

NID2 DENND2A KLF11 PDGFRB EFEMP2 PHF8 DENND2B ZEB2 CDAN1 SIDT2 FBN1 FBN2 SCUBE2 CCBE1 TMLHE LTBP1 FBN3

1.67e-0414669217PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

PDGFRB MFAP2 FBN1 FBN2 HMCN1

1.90e-04122925gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_1000

ADAMTS2 OBSL1 ZEB2 CCN4 ARAP1

1.98e-04123925gudmap_developingGonad_e16.5_epididymis_1000_k3
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_100

PDGFRB FBN1 HMCN1

2.14e-0427923gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

DENND2A PDGFRB OBSL1 PHF8 DENND2B ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

2.33e-048279212gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

ADAMTS3 SZT2 PDGFRB OBSL1 DENND2B ZEB2 MFAP2 FBN1 FBN2 HMCN1 UHRF1 LTBP1

2.44e-048319212gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000

NID2 KLF11 ADAMTS3 ADAMTS2 PLPPR5 CCN4 FBN2 DCAF12L1 LTBP1 CKAP2 ARAP1 EPHB1

2.61e-048379212gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000

DENND2A KLF11 PDGFRB OBSL1 DENND2B ZEB2 MFAP2 FBN1 HMCN1 CCBE1 UHRF1 LTBP1

3.26e-048589212gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000

ADAMTS3 PDGFRB CXCL13 ZMAT4 NELL1 MFAP2 FBN1 FBN2 FNDC10 HMCN1 LTBP1

3.29e-047349211gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlasgudmap_RNAseq_e15.5_Podocytes_2500_K0

ABHD17A NID2 ADAMTS2 EFEMP2 VPS8 COMTD1 CCN4 NELL1 MFAP2 FBN1 CCBE1 SQSTM1 LTBP1 ARAP1

3.91e-0411439214gudmap_RNAseq_e15.5_Podocytes_2500_K0
CoexpressionAtlaskidney_adult_RenCorpuscGlomer_k-means-cluster#4_top-relative-expression-ranked_1000

PDGFRB CXCL13 MECOM ZMAT4 ZEB2

4.64e-04148925gudmap_kidney_adult_RenCorpuscGlomer_k4_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

ADAMTS3 PDGFRB ZEB2 MFAP2 FBN1 FBN2 UHRF1 LTBP1

5.02e-04423928gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

ADAMTS2 CCN4 MFAP2 NEK1 FBN1 FBN2 DCAF12L1 HMCN1 TMLHE SOCS5 ARAP1

6.16e-047919211gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000

ADAMTS3 CXCL13 NELL1 HMCN1

6.61e-0491924gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

PDGFRB ZEB2 FBN1 HMCN1 UHRF1

7.61e-04165925gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

RNASE12 MECOM FBN2 HMCN1 LTBP1

7.82e-04166925gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_100

DCAF12L1 TMLHE

8.17e-0410922gudmap_developingGonad_e18.5_ovary_100_k3
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

PDGFRB DENND2B NELL1 MFAP2 FBN1 FBN2 HMCN1

9.23e-04357927gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

ADAMTS2 PDGFRB EFEMP2 CXCL13 DENND2B FBN1 HMCN1 LTBP1

9.42e-04466928GSM777050_500
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

PDGFRB MFAP2 FBN1 FBN2 HMCN1 LTBP1

9.61e-04261926gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#1_top-relative-expression-ranked_200

RNASE12 FBN2 LTBP1

1.11e-0347923gudmap_kidney_P4_CapMesRenVes_Crym_k1_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

ADAMTS3 ADAMTS2 PDGFRB ZEB2 FBN1

1.18e-03182925gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_1000

ADAMTS2 OBSL1 ZEB2 CCN4 ARAP1

1.24e-03184925gudmap_developingGonad_e14.5_ epididymis_1000_k2
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NID2 DENND2A ZEB1 ADAMTS2 PDGFRB ZEB2 FBN1 HMCN1 CCBE1 LTBP1

2.16e-1120097103dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ZEB1 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 LTBP1

3.84e-10191979107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

NID2 ADAMTS2 PDGFRB EFEMP2 PLPPR5 CCN4 MFAP2 FBN1 HMCN1

3.84e-10191979aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ZEB1 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 LTBP1

3.84e-10191979bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS2 PDGFRB EFEMP2 CCN4 NELL1 FBN1 SCUBE2 CCBE1

4.02e-10192979ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 ADAMTS2 PDGFRB CXCL13 PLPPR5 MFAP2 FBN1 HMCN1 CCBE1

4.21e-1019397959b8186d0221fba06a16157e9d148399ed801f38
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 ADAMTS2 PDGFRB CXCL13 PLPPR5 MFAP2 FBN1 HMCN1 CCBE1

4.21e-10193979dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 ADAMTS2 PDGFRB CXCL13 PLPPR5 MFAP2 FBN1 HMCN1 CCBE1

4.21e-1019397903678162648bd5b1d65a5450b60c8863edbf95c7
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

5.77e-102009794dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ZEB1 PDGFRB CXCL13 CCN4 FBN1 HMCN1 CCBE1 LTBP1

5.77e-102009798ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

5.77e-10200979bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

5.77e-10200979ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

5.77e-102009798256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ZEB1 ADAMTS2 PDGFRB ZEB2 FBN1 HMCN1 CCBE1 LTBP1

5.77e-10200979b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 ADAMTS3 PDGFRB EFEMP2 NELL1 FBN1 SCUBE2 CCBE1 LTBP1

5.77e-10200979a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ZEB1 PDGFRB ZEB2 CCN4 FBN1 HMCN1 CCBE1 LTBP1

5.77e-1020097958b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NID2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

7.42e-0918597887c416d14ca6255bee39b16e7571553e36ee3069
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 FBN2 HMCN1

7.74e-0918697894d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

9.53e-09191978a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 CXCL13 PLPPR5 CCN4 NELL1 MFAP2 FBN1 ARAP1

9.53e-09191978053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NID2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

9.53e-091919780fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

9.93e-091929789093a9e94a25682d109a7f6edc256a25a61103a0
ToppCelldroplet-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB DEFB104A EFEMP2 CCN4 MFAP2 FBN1

9.93e-0919297838d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

9.93e-09192978d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

9.93e-091929789ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB DEFB104A EFEMP2 CCN4 MFAP2 FBN1

9.93e-0919297804d155897ed075c359933080e36a4ab2150b6e9f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS2 CCN4 NELL1 FBN1 SCUBE2 CCBE1 LTBP1

9.93e-09192978df1545670370fb1010c567cd059c2783eab315f7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS3 ADAMTS2 EFEMP2 NELL1 FBN1 SCUBE2 CCBE1

9.93e-09192978dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB DEFB104A EFEMP2 CCN4 MFAP2 FBN1

9.93e-0919297884149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.03e-08193978f1199518c3626fd29bfce65070dd21a660671213
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

DENND2A ADAMTS2 PDGFRB CCN4 FBN1 HMCN1 CCBE1 LTBP1

1.08e-0819497803a269f75a481ea54aea8e6444605db8d6df493d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.12e-08195978edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS3 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.12e-081959783c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 LTBP1

1.17e-08196978b8759e6231e0254797d6c30930407b79440c57bb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 ADRA2C CCBE1 LTBP1

1.17e-08196978ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 ADRA2C CCBE1 LTBP1

1.17e-0819697830ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

NID2 ADAMTS2 PDGFRB EFEMP2 MFAP2 FBN1 HMCN1 LTBP1

1.17e-08196978275e153347caf94edc0c50021bbab49c8696fecb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.21e-08197978ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.21e-0819797837f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ZEB1 PDGFRB CCN4 FBN1 HMCN1 CCBE1 LTBP1

1.21e-0819797844673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS2 PDGFRB EFEMP2 CXCL13 DENND2B CCN4 MFAP2 FBN1

1.26e-08198978229588189825b1080181db9515185677b742c668
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.26e-08198978ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS2 PDGFRB ZEB2 CCN4 MFAP2 FBN1 FBN2 HMCN1

1.26e-08198978a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

NID2 ADAMTS2 PDGFRB EFEMP2 OBSL1 DENND2B FBN1 LTBP1

1.26e-08198978e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NID2 PDGFRB CCN4 MFAP2 FBN1 HMCN1 CCBE1 LTBP1

1.31e-081999787a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 DENND2A PDGFRB EFEMP2 CCN4 FBN1 CCBE1 LTBP1

1.31e-08199978fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 DENND2A PDGFRB EFEMP2 CCN4 FBN1 CCBE1 LTBP1

1.31e-08199978a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 DENND2A PDGFRB EFEMP2 CCN4 FBN1 CCBE1 LTBP1

1.31e-08199978211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS3 PDGFRB EFEMP2 ZEB2 NELL1 FBN1 CCBE1 LTBP1

1.31e-0819997830d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 LTBP1

1.31e-0819997821335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZEB1 PDGFRB EFEMP2 NELL1 MFAP2 FBN1 FBN2 SCUBE2

1.31e-08199978e78f661b40da34768469549b6e755d330be6bbd8
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 DENND2A PDGFRB EFEMP2 CCN4 FBN1 CCBE1 LTBP1

1.31e-081999781a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.31e-081999789503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 CCBE1 LTBP1

1.36e-08200978e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS3 PDGFRB EFEMP2 NELL1 FBN1 SCUBE2 CCBE1 LTBP1

1.36e-082009789b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

NID2 ADAMTS2 PDGFRB EFEMP2 CCN4 FBN1 HMCN1 LTBP1

1.36e-082009784f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS2 PDGFRB EFEMP2 MFAP2 FBN1 HMCN1 CCBE1 LTBP1

1.36e-082009786e3d1ae0ef84d3075afa40129a41169996462672
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS2 PDGFRB EFEMP2 ZEB2 CCN4 MFAP2 FBN1 FBN2

1.36e-082009783dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ADAMTS2 PDGFRB ZEB2 FBN1 HMCN1 CCBE1 LTBP1

1.36e-08200978cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ADAMTS2 PDGFRB ZEB2 FBN1 HMCN1 CCBE1 LTBP1

1.36e-08200978311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS2 PDGFRB EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

1.36e-0820097854806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

NID2 ZEB1 PDGFRB CCN4 FBN1 HMCN1 LTBP1

8.30e-08167977d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NID2 DENND2A ZEB1 PDGFRB MECOM FBN1 LTBP1

1.49e-07182977fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ADAMTS2 EFEMP2 CCN4 MFAP2 FBN1 HMCN1 LTBP1

1.61e-071849770b336489c10e8c3c957795dd845454f03404382b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.61e-07184977e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADAMTS2 DENND2B CCN4 MFAP2 FBN1 FBN2 HMCN1

1.67e-07185977427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZEB1 MECOM ZEB2 FBN1 SCUBE2 LTBP1 EPHB1

1.67e-071859771ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 PDGFRB EFEMP2 MFAP2 FBN1 FBN2 HMCN1

1.67e-07185977785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 PDGFRB EFEMP2 MFAP2 FBN1 FBN2 HMCN1

1.67e-0718597797a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAMTS2 PDGFRB DENND2B ZEB2 FBN1 CCBE1 LTBP1

1.73e-07186977a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAMTS2 PDGFRB DENND2B ZEB2 FBN1 CCBE1 LTBP1

1.73e-07186977f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

DENND2A ZEB1 ADAMTS2 FBN1 HMCN1 CCBE1 LTBP1

1.79e-07187977bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1

1.93e-0718997771397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1

1.93e-071899774eea4759520c312bd17a681034d8074e47093d2b
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB EFEMP2 DCAF12L2 MFAP2 FBN1

1.93e-07189977bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS3 EFEMP2 NELL1 FBN1 SCUBE2 CCBE1

1.93e-07189977a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A PDGFRB EFEMP2 NELL1 FBN1 SCUBE2 CCBE1

1.93e-07189977e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB EFEMP2 DCAF12L2 MFAP2 FBN1

1.93e-07189977cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ADAMTS2 PDGFRB EFEMP2 DCAF12L2 MFAP2 FBN1

1.93e-0718997787323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS3 PDGFRB NELL1 FBN1 SCUBE2 CCBE1

1.93e-071899772a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

1.93e-07189977c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

2.00e-071909772e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 LTBP1

2.00e-0719097770c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

2.00e-07190977445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 CCBE1

2.07e-07191977a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS3 PDGFRB NELL1 FBN1 SCUBE2 CCBE1

2.07e-07191977b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

2.07e-07191977806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1

2.07e-0719197739092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 LTBP1

2.07e-071919777b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 CCBE1

2.07e-071919778f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1

2.07e-07191977ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 LTBP1

2.07e-07191977cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ADAMTS3 PDGFRB EFEMP2 NELL1 FBN1 CCBE1

2.15e-071929776f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1

2.15e-07192977bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ADAMTS2 PDGFRB ZEB2 CCN4 FBN1 CCBE1

2.15e-071929775105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

NID2 EFEMP2 DENND2B ZEB2 MFAP2 FBN1 LTBP1

2.15e-071929777a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A PDGFRB EFEMP2 CCN4 NELL1 FBN1 CCBE1

2.15e-07192977162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NID2 PDGFRB DCAF12L2 MFAP2 FBN1 CCBE1 LTBP1

2.15e-07192977b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PDGFRB ZEB2 CCN4 FBN1 CCBE1 LTBP1

2.15e-071929779333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 PDGFRB DENND2B ZEB2 CCN4 FBN1 CCBE1

2.15e-071929770ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
Drugflufenacet

DEFA1 DEFA3 COASY

1.53e-066983CID000086429
Drugdesmosine

EFEMP2 MFAP2 FBN1 FBN2 FBN3

3.25e-0653985CID000025435
Drug1xqc

PDGFRB FBN2 FBN3

1.24e-0511983CID005287617
Drug2-methoxyethoxy)acetic acid

DEFA1 DEFA3

1.83e-052982CID000027642
Drugp-sulfobenzyl alcohol

DEFA1 DEFA3

1.83e-052982CID000441138
Drugtebuquine

KRT81 KRT83

1.83e-052982CID000071991
Drug3,5-di-O-galloylquinic acid

KRT81 KRT83

1.83e-052982CID000460896
Drugmelicopicine

KRT81 KRT83

1.83e-052982CID000101253
Drug1,2,5,6-tetramethylnaphthalene

DEFA1 DEFA3

1.83e-052982CID006427081
Drug1,4,5-trimethylnaphthalene

DEFA1 DEFA3

1.83e-052982CID000016478
DrugChrysin [480-40-0]; Up 200; 15.8uM; HL60; HT_HG-U133A

INHBC ACVR1B PRDM2 ZNF668 FBN1 SCUBE2 SLC17A7

2.25e-051969873106_UP
DrugPentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A

INHBC KRT83 MUC5B ACVR1B FBN2 SLC17A6 EPHB1

2.25e-051969875629_UP
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

SZT2 OAS1 ACVR1B TAF6L NEK1 ARAP1 ZNF304

2.32e-051979875276_UP
DrugAndrosterone [53-41-8]; Up 200; 13.8uM; PC3; HT_HG-U133A

SZT2 ZNF629 OAS1 ACVR1B HES2 SIDT2 KRTAP9-9

2.32e-051979874635_UP
DrugAzathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

ZEB1 EFEMP2 OAS1 SIDT2 FBN2 CHRNA10 ARAP1

2.32e-051979875262_UP
DrugLGD2226

ADAMTS2 PRDM2 SLC17A7 SLC17A6

4.58e-0546984CID011560224
Drug4-ethylbenzoate

DEFA1 DEFA3

5.49e-053982CID000012086
Drugsulfonamide-3

KRT81 KRT83

5.49e-053982CID009847197
DrugATBI

KRT81 KRT83 KRT86

6.02e-0518983CID000505862
DrugTAAD

ACVR1B FBN1 FBN2

9.72e-0521983CID000133445
Druglactucin

KRT81 KRT83

1.09e-044982CID000442266
DrugLactupicrin

KRT81 KRT83

1.09e-044982CID000174880
Drugtopanol A

DEFA1 DEFA3

1.09e-044982CID000015884
Drug4-fluorobenzoyl chloride

DEFA1 DEFA3

1.09e-044982CID000067879
Drugxenognosin B

DEFA1 DEFA3

1.09e-044982CID005280551
DrugAC1L3OZP

DEFA1 DEFA3

1.09e-044982CID000092862
Drugsperabillin A

DEFA1 DEFA3

1.09e-044982CID006441177
DiseaseBeaded hair

KRT81 KRT83 KRT86

2.39e-083863cv:C0546966
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2 FBN3

2.39e-083863DOID:65 (implicated_via_orthology)
DiseaseMONILETHRIX

KRT81 KRT83 KRT86

2.39e-083863158000
Diseasemonilethrix (is_implicated_in)

KRT81 KRT83 KRT86

2.39e-083863DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT83 KRT86

9.54e-084863C0546966
Diseasedepressive symptom measurement, response to antidepressant

CXCL13 EVPL MUC5B DCAF12L2 DIP2C

6.06e-0688865EFO_0007006, GO_0036276
Diseasehair disease (is_implicated_in)

KRT81 KRT86

8.40e-062862DOID:421 (is_implicated_in)
DiseaseHennekam syndrome (is_implicated_in)

ADAMTS3 CCBE1

2.51e-053862DOID:0060366 (is_implicated_in)
DiseaseHennekam lymphangiectasia-lymphedema syndrome

ADAMTS3 CCBE1

2.51e-053862C0340834
Diseaseaortic aneurysm (is_implicated_in)

EFEMP2 FBN1

2.51e-053862DOID:3627 (is_implicated_in)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

5.02e-054862DOID:0060249 (is_implicated_in)
DiseaseOsteoarthritis, Knee

SBNO1 LTBP1

5.02e-054862C0409959
DiseaseFEV/FEC ratio

ABHD17A NID2 ADAMTS2 MECOM ACVR1B DENND2B ZEB2 MFAP2 FBN1 HMCN1 LTBP1 DMBT1 ARAP1

5.45e-0512288613EFO_0004713
Diseaseaortic dissection (is_marker_for)

EFEMP2 EPHB1

2.32e-048862DOID:0080685 (is_marker_for)
DiseaseOsteitis Deformans

SQSTM1 ZNF687

2.98e-049862C0029401
Diseaseglycerophospholipid measurement

PAQR9 SIDT2 FBN3

4.00e-0449863EFO_0007630
DiseaseLiver Cirrhosis, Experimental

PAQR9 NID2 PDGFRB INHBC CXCL13 ZEB2 FBN1 FBXO9 LTBP1

4.26e-04774869C0023893
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

EFEMP2 FBN1 FBN2

5.04e-0453863C4707243
DiseaseHeschl's gyrus morphology measurement

VPS8 FBN2 MED12L

5.04e-0453863EFO_0005852
Diseaserheumatic heart disease (biomarker_via_orthology)

ZEB1 ZEB2

5.44e-0412862DOID:0050827 (biomarker_via_orthology)
DiseaseFamilial Nonmedullary Thyroid Cancer

ZEB1 ZEB2 BEGAIN

7.61e-0461863C3501844
DiseaseNonmedullary Thyroid Carcinoma

ZEB1 ZEB2 BEGAIN

7.61e-0461863C3501843
Diseaseascending aortic diameter

C3orf20 FBN1 FBN2 HMCN1

7.63e-04140864EFO_0021787
Diseasesevere aplastic anemia

ZMAT4 FBN2

8.60e-0415862EFO_0006927
DiseaseMalignant neoplasm of breast

NID2 ZEB1 DLL4 MECOM ZEB2 ZNF668 SBNO1 DIP2C HOXB13 SLC17A6

1.13e-0310748610C0006142
Diseasetransient cerebral ischemia (biomarker_via_orthology)

DLL4 SLC17A7 LTBP1 SLC17A6

1.17e-03157864DOID:224 (biomarker_via_orthology)
DiseaseDisease Exacerbation

ZEB1 ABCA13 XPC ZEB2

1.40e-03165864C0235874
DiseaseDisproportionate short stature

OBSL1 NEK1 FBN1

1.50e-0377863C0878659
Diseaseunipolar depression, bipolar disorder, schizophrenia

ADAMTS2 CCBE1

1.54e-0320862EFO_0003761, MONDO_0004985, MONDO_0005090
Diseaseglomerulonephritis (biomarker_via_orthology)

FBN1 LTBP1

1.54e-0320862DOID:2921 (biomarker_via_orthology)
Diseasemonocyte count

SZT2 PDGFRB INHBC EFEMP2 RNASE12 MECOM DENND2B DEFA3 SQSTM1 MED12L HNRNPLL

1.55e-0313208611EFO_0005091
DiseasePapillary thyroid carcinoma

ZEB1 ZEB2 BEGAIN

2.05e-0386863C0238463
DiseaseNeoplasm Invasiveness

ZEB1 XPC ZEB2 HOXB13

2.09e-03184864C0027626
Diseasedental caries

ADAMTS3 ADAMTS2 PLPPR5 C3orf20

2.21e-03187864EFO_0003819
Diseaseglioblastoma (is_implicated_in)

PDGFRB DMBT1

2.22e-0324862DOID:3068 (is_implicated_in)
Diseasecoronary artery disease

ZEB1 ADAMTS3 INHBC RNASE12 MECOM DENND2B ZEB2 NELL1 FBN2 UHRF1

2.47e-0311948610EFO_0001645

Protein segments in the cluster

PeptideGeneStartEntry
RRVLTYGCCSEPYPD

CHRNA10

211

Q9GZZ6
RYYRLLQSPLCAGCS

ANAPC2

211

Q9UJX6
IYCSDTALYCPEERR

BEGAIN

226

Q9BUH8
CYTDYCNRIDLRVPS

ACVR1B

96

P36896
SYSLYGICREACQVP

ADRA2C

401

P18825
RSYTCTCRPGYTGVD

DLL4

306

Q9NR61
YYCSLRGIPRQCIPE

ABCA13

4821

Q86UQ4
CMYVRCVPGARYTVL

ABHD17A

101

Q96GS6
CDYSGDRPRYAIGVC

CCN4

101

O95388
INIPGSYRCKCTRGY

FBN3

1781

Q75N90
GSYLCTCPAGYTLRE

FBN3

2186

Q75N90
RLPEVYCVISRLGCF

DENND2B

791

P78524
YGIRSEYCIRKIICP

BPTF

1956

Q12830
YTCCPYIGELRKLLA

CDAN1

796

Q8IWY9
CRMEVLSRYCSIPGY

ADAMTS2

1071

O95450
VCRPNAALCRVYYEA

CKAP2

666

Q8WWK9
YAYVVDACQPTCRGL

MUC5B

701

Q9HC84
YAGCCTLKIEYARPT

HNRNPLL

231

Q8WVV9
RYTCRYCGKIFPRSA

MECOM

911

Q03112
CVPSEGDYRFRICTV

OBSL1

581

O75147
EASPICTCRTGYYRA

EPHB1

296

P54762
SRRVCICLATFPYVY

OR5M11

136

Q96RB7
CSSPERCILAYLYDL

MED12L

921

Q86YW9
RTCIGTPYYLSPEIC

NEK1

161

Q96PY6
RCQYVVTCAGLYSDR

L2HGDH

251

Q9H9P8
LPCDSYREGYSACVA

HES2

81

Q9Y543
CCVPTARRPLSLLYY

INHBC

316

P55103
CITAAPYRGISCYRG

KRT86

26

O43790
IRLPYCRENVCLTYC

DCAF12L2

301

Q5VW00
TGDCCYINPLVRRTV

PLPPR5

106

Q32ZL2
NLPVRYTCICYEGYR

LTBP1

891

Q14766
EGYRCYRSASPTVPR

EVPL

2016

Q92817
LKERCFRGSSYPVCV

OAS1

41

P00973
QGVLEVYYTSLRCRC

CXCL13

21

O43927
GLYRCDCVPGYIRVD

NELL1

456

Q92832
ECFILSGYRRLPCTA

PAQR9

56

Q6ZVX9
NTRGSYRCVCPRGYR

HMCN1

5291

Q96RW7
LPGSYRCECRSGYEF

NID2

821

Q14112
RPRYETGVCAYLVAV

CCN6

106

O95389
SYKDPYSICVRGECV

ADAMTS3

671

O15072
CYCRIPACIAGERRY

DEFA1

66

P59665
PACIAGERRYGTCIY

DEFA1

71

P59665
CYCRIPACIAGERRY

DEFA3

66

P59666
PACIAGERRYGTCIY

DEFA3

71

P59666
LPEVYCIVSRLGCFS

DENND2A

661

Q9ULE3
LSLVCRGFYICARDP

FBXO9

216

Q9UK97
TRCIDVRPGYCYTAL

FBN1

326

P35555
VRPGYCYTALTNGRC

FBN1

331

P35555
CRCPTGYYLNEDTRV

FBN1

1631

P35555
YTRFPCERVLLGASC

FNDC10

116

F2Z333
GRGSPCIQCRYDSYR

C3orf20

741

Q8ND61
INTLGSYRCECREGY

CCBE1

151

Q6UXH8
CSAYYERCLQLLRPG

COMTD1

191

Q86VU5
YRIGRCPNTYACCLR

DEFB104A

46

Q8WTQ1
YPSREVAICLDPYCG

DIP2C

1171

Q9Y2E4
RRNYVCSFPGCRKTY

KLF11

391

O14901
CRRTCYYPTTVCLPG

KRTAP9-2

116

Q9BYQ4
CRRTCYYPTTVCLPG

KRTAP9-4

101

Q9BYQ2
CRPICSGLLTYRQPY

KRTAP16-1

401

A8MUX0
YRPCYSILRRPACVT

KRTAP16-1

426

A8MUX0
PACVTSYSCRPVYFR

KRTAP16-1

436

A8MUX0
SYSCRPVYFRPSCTE

KRTAP16-1

441

A8MUX0
CRRTCYYPTTVCLPG

KRTAP9-9

96

Q9BYP9
IRLPYFRDNVCLTYC

DCAF12L1

301

Q5VU92
ECPQGYYLSEDTRIC

FBN2

1676

P35556
GYRCVDTNRCVEPYI

EFEMP2

306

O95967
GYYSCRVSRSSLKPC

HOXB13

86

Q92826
RAYDPSSRCYRGCVL

DMBT1

2366

Q9UGM3
TVCQLIEGTRYPACR

RNASE12

106

Q5GAN4
CRAGTYYDGARERCI

SCUBE2

641

Q9NQ36
LGLVCEIGLRCRTYY

SBNO1

1291

A3KN83
EIGLRCRTYYVLCGS

SBNO1

1296

A3KN83
PVGVNTECYRIYEAC

RXYLT1

331

Q9Y2B1
YYCRVRGGRCAVLSC

DEFB103A

31

P81534
DCREEQYPCTRLYSI

MFAP2

96

P55001
CITAAPYRGISCYRG

KRT83

31

P78385
ICPYCNREFTYIGSL

PRDM2

1456

Q13029
CTKGGPIYIITEYCR

PDGFRB

671

P09619
QYGCCSLVYLRPRSS

OR10Q1

256

Q8NGQ4
LGPYVRCLVGSVLYC

TAF6L

231

Q9Y6J9
DGPRTRCPVYIYSCS

SZT2

1231

Q5T011
RCPVYIYSCSLEALR

SZT2

1236

Q5T011
VLYTDCIRQCSGPLY

SIDT2

671

Q8NBJ9
YICRAVICRCTTYDG

SOCS5

486

O75159
VVDCTCFGLPRRYII

SLC17A7

51

Q9P2U7
LVYISCCLAGRAYPL

VPS8

726

Q8N3P4
DRYVAICSPLLYSTC

OR5P3

121

Q8WZ94
VGTRYKCSVCPDYDL

SQSTM1

136

Q13501
YEYEPPCTSLCARVQ

ACD

416

Q96AP0
PVIVYRCVDYITQCG

ARAP1

971

Q96P48
VYCLRTPRGLEMYDC

ANKUB1

126

A6NFN9
YSCCPRLASVLLYSD

COASY

141

Q13057
DCTCFGLPRRYIIAI

SLC17A6

61

Q9P2U8
AGLRPYSCERCGKAY

ZNF668

191

Q96K58
CPTCRRETVLFTDYG

RNF208

186

Q9H0X6
TCPYCDRGYKRFTSL

ZEB1

171

P37275
VFSCPACRYDLGRSY

UHRF1

756

Q96T88
GYRFCSPCQRYVSLE

ZCCHC4

376

Q9H5U6
RVYPCRYCTEGKRTF

ZNF687

1021

Q8N1G0
PVYCLCRLPYDVTRF

PHF8

41

Q9UPP1
ARPYVCSECGKAYIS

ZNF304

556

Q9HCX3
ILGYCRGEAVYSRDC

XPC

666

Q01831
LTCPYCDRGYKRLTS

ZEB2

211

O60315
PYKCGECRRAFYRSS

ZNF629

261

Q9UEG4
GYRQLCGCYLTRDDV

TMLHE

396

Q9NVH6
SPYQRRDSDRYCGLC

ZMAT4

136

Q9H898
CITAAPYRGISCYRG

KRT81

26

Q14533
TYGPFCAERLRRTYA

MYO7B

1161

Q6PIF6