Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 OR12D1 P2RY1 P2RY12 GPR158 FZD3 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4M2B OR4F6 OR1D2

1.53e-218846929GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 ABCA1 OR5AC1 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 OR12D1 P2RY1 P2RY12 GPR158 FZD3 AGTR2 PKD1 OR4M1 TRPV4 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4M2B OR4F6 OR1D2

1.12e-1913536932GO:0004888
GeneOntologyMolecularFunctiontransporter activity

SLC5A11 GPR89B ABCA1 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 SLC6A16 ABCA12 SLC26A2 CLN3 SLC6A17 SLC22A4 PKD1 KCNK1 GPR89A SLCO1B3 TRPV4 LRRC8B SLC13A2 SLCO6A1 SLC2A1 SLC6A14

3.72e-1312896925GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC5A11 GPR89B ABCA1 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 SLC6A16 ABCA12 SLC26A2 SLC6A17 SLC22A4 PKD1 KCNK1 GPR89A SLCO1B3 TRPV4 LRRC8B SLC13A2 SLCO6A1 SLC2A1 SLC6A14

4.64e-1311806924GO:0022857
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC5A11 SLC9A2 SLC12A3 SLC41A3 SLC15A2 SLC6A16 SLC26A2 SLC6A17 SLC22A4 SLCO1B3 SLC13A2 SLCO6A1 SLC6A14

2.36e-112966913GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC5A11 ABCA1 SLC9A2 SLC12A3 SLC41A3 SLC15A2 SLC6A16 ABCA12 SLC26A2 SLC6A17 SLC22A4 SLCO1B3 SLC13A2 SLCO6A1 SLC6A14

6.57e-114776915GO:0022804
GeneOntologyMolecularFunctionolfactory receptor activity

OR3A1 OR12D3 OR4M2 OR51B5 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

2.38e-094316913GO:0004984
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC5A11 GPR89B SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 SLC26A2 PKD1 KCNK1 GPR89A TRPV4 LRRC8B SLC13A2 SLC6A14

8.79e-097936916GO:0015075
GeneOntologyMolecularFunctionsymporter activity

SLC5A11 SLC12A3 SLC15A2 SLC6A16 SLC6A17 SLC22A4 SLC13A2 SLC6A14

4.77e-08150698GO:0015293
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 KCND1 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

5.24e-074656911GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

1.42e-066276912GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 SLC26A2 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

1.66e-067586913GO:0015318
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A11 SLC9A2 SLC12A3 SLC41A3 KCNK1 SLC13A2 SLC6A14

2.06e-06171697GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 KCND1 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

2.57e-066646912GO:0008324
GeneOntologyMolecularFunctionG protein-coupled ADP receptor activity

P2RY1 P2RY12

3.52e-053692GO:0001621
GeneOntologyMolecularFunctiontachykinin receptor activity

TACR2 TACR1

3.52e-053692GO:0004995
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A11 SLC12A3 SLC15A2 SLC13A2 SLC6A14

5.73e-05119695GO:0015294
GeneOntologyMolecularFunctionodorant binding

OR12D3 OR5AC1 OR8B4 OR12D2 OR12D1

7.80e-05127695GO:0005549
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC5A11 SLC9A2 SLC12A3 SLC41A3 SLC15A2 SLC13A2 SLC6A14

8.00e-05301697GO:0022853
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

AGTR2 TACR2 TACR1 SSTR4 F2RL2

9.71e-05133695GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

AGTR2 TACR2 TACR1 SSTR4 F2RL2

1.24e-04140695GO:0001653
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A4 SLC6A14

1.75e-046692GO:0015226
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GPR89B SLC12A3 SLC26A2 GPR89A LRRC8B

1.76e-04151695GO:0008509
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A11 SLC12A3 SLC13A2 SLC6A14

1.78e-0481694GO:0015370
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A TRPV4 LRRC8B

1.80e-04459698GO:0005216
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

GPR89B CATSPER1 KCND1 KCNK1 GPR89A

4.17e-04182695GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

GPR89B CATSPER1 KCND1 KCNK1 GPR89A

4.39e-04184695GO:0022832
GeneOntologyMolecularFunctionchannel activity

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A TRPV4 LRRC8B

4.43e-04525698GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A TRPV4 LRRC8B

4.48e-04526698GO:0022803
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A2 SLCO1B3 SLC13A2 SLCO6A1 SLC2A1 SLC6A14

5.24e-04293696GO:0008514
GeneOntologyMolecularFunctionlipid transporter activity

ABCA1 ABCA12 CLN3 SLCO1B3 SLC2A1

5.85e-04196695GO:0005319
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A2 SLCO1B3 SLC13A2 SLC2A1 SLC6A14

7.48e-04207695GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A2 SLCO1B3 SLC13A2 SLC2A1 SLC6A14

7.65e-04208695GO:0005342
GeneOntologyMolecularFunctionneuropeptide receptor activity

TACR2 TACR1 SSTR4

8.17e-0453693GO:0008188
GeneOntologyMolecularFunctionG protein-coupled purinergic nucleotide receptor activity

P2RY1 P2RY12

8.96e-0413692GO:0045028
GeneOntologyMolecularFunctiongated channel activity

GPR89B CATSPER1 KCND1 KCNK1 GPR89A TRPV4

1.04e-03334696GO:0022836
GeneOntologyMolecularFunctioncholesterol binding

ABCA1 SCAP TMEM97

1.06e-0358693GO:0015485
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A4 SLC6A14

1.20e-0315692GO:0015651
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLC15A2 SLCO1B3

1.37e-0316692GO:0035673
GeneOntologyMolecularFunctionWnt receptor activity

FZD3 PKD1

1.55e-0317692GO:0042813
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

GPR89B GPR89A

1.55e-0317692GO:0008308
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B3 SLCO6A1

1.74e-0318692GO:0015347
GeneOntologyMolecularFunctionsterol binding

ABCA1 SCAP TMEM97

1.91e-0371693GO:0032934
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCA12 SLCO1B3 SLC2A1

2.07e-0373693GO:0170055
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC6A16 SLC22A4

2.37e-0321692GO:0005326
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RY1 P2RY12

2.60e-0322692GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RY1 P2RY12

2.60e-0322692GO:0001614
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9A2 SLC12A3 KCND1 KCNK1

2.67e-03167694GO:0015079
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC5A11 SLC2A1

3.35e-0325692GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC5A11 SLC2A1

3.35e-0325692GO:0015149
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND1 KCNK1

3.91e-0327692GO:0015271
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC5A11 SLC2A1

3.91e-0327692GO:0015145
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R1 TAS2R9

3.91e-0327692GO:0033038
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA12

4.20e-0328692GO:0140326
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC5A11 SLC2A1

4.50e-0329692GO:0051119
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A2 SLC13A2

5.13e-0331692GO:0005310
GeneOntologyMolecularFunctionalcohol binding

ABCA1 SCAP TMEM97

5.31e-03102693GO:0043178
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GPR89B GPR89A LRRC8B

5.46e-03103693GO:0005253
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC22A4 SLC6A14

5.80e-0333692GO:0072349
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R1 TAS2R9

5.80e-0333692GO:0008527
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC13A2 SLC6A14

6.51e-0335692GO:0005343
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CATSPER1 KCND1 PKD1 KCNK1 TRPV4

6.65e-03343695GO:0005261
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC5A11 SLC2A1

9.27e-0342692GO:0015144
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLC15A2 SLCO1B3

9.27e-0342692GO:0042887
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A2 SLC41A3

9.70e-0343692GO:0140828
GeneOntologyMolecularFunctioncalcium channel activity

CATSPER1 PKD1 TRPV4

1.01e-02129693GO:0005262
GeneOntologyMolecularFunctionsteroid binding

ABCA1 SCAP TMEM97

1.10e-02133693GO:0005496
GeneOntologyMolecularFunctionantiporter activity

SLC9A2 SLC41A3 SLC26A2

1.21e-02138693GO:0015297
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA12

1.25e-0249692GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA12

1.35e-0251692GO:0140303
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 ABCA1 OR5AC1 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 OR12D1 P2RY1 P2RY12 GPR158 FZD3 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 ADCY7 OR4M2B OR4F6 OR1D2

1.27e-1813956931GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OPN4 OR4N2 OR8B4 OR12D2 OR12D1 PKD1 OR4M1 TACR1 OR4M2B OR4F6 OR1D2

1.63e-117226918GO:0051606
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC5A11 GPR89B SLC9A2 CATSPER1 SLC12A3 SLC41A3 P2RY1 SLC15A2 P2RY12 KCND1 SLC6A16 SLC26A2 SLC6A17 SLC22A4 PKD1 KCNK1 GPR89A SLCO1B3 TRPV4 TACR2 LRRC8B SLC13A2 SLC6A14

4.50e-1113746923GO:0006811
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

5.30e-114856915GO:0050907
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OPN4 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

6.31e-115826916GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

1.56e-105246915GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

2.83e-105476915GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR3A1 OR12D3 OR4M2 OR51B5 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

1.66e-094326913GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR3A1 OR12D3 OR4M2 OR51B5 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

4.03e-094656913GO:0007608
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GPR89B SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 P2RY12 KCND1 SLC6A16 SLC26A2 SLC6A17 PKD1 KCNK1 GPR89A TRPV4 LRRC8B SLC13A2 SLC6A14

1.69e-0811156918GO:0034220
GeneOntologyBiologicalProcesssodium ion transport

SLC5A11 SLC9A2 SLC12A3 SLC41A3 SLC6A16 SLC6A17 SLC22A4 KCNK1 SLC13A2 SLC6A14

2.56e-082756910GO:0006814
GeneOntologyBiologicalProcessorganic cation transport

P2RY1 P2RY12 CLN3 SLC6A17 SLC22A4 AGTR2 TACR2 SLC6A14

2.86e-08145698GO:0015695
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

OR4M2 ABCA1 HTR1D GPR61 P2RY1 P2RY12 OR4M1 GPR101 SSTR4 ADCY7

3.71e-082866910GO:0007188
GeneOntologyBiologicalProcessregulation of cilium movement involved in cell motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

1.45e-0737695GO:0060295
GeneOntologyBiologicalProcessregulation of cilium-dependent cell motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

1.45e-0737695GO:1902019
GeneOntologyBiologicalProcesspositive regulation of cilium-dependent cell motility

OR4M2 OR4M1 TACR2 TACR1

3.39e-0718694GO:2000155
GeneOntologyBiologicalProcesspositive regulation of flagellated sperm motility

OR4M2 OR4M1 TACR2 TACR1

3.39e-0718694GO:1902093
GeneOntologyBiologicalProcesssensory perception

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 TAS2R9 OR5AC1 OPN4 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4M2B OR4F6 OR1D2

3.59e-0710726916GO:0007600
GeneOntologyBiologicalProcesspositive regulation of cilium movement

OR4M2 OR4M1 TACR2 TACR1

4.28e-0719694GO:0003353
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A2 SLC12A3 SLC41A3 SLC6A16 SLC6A17 KCNK1 SLC13A2 SLC6A14

4.61e-07208698GO:0035725
GeneOntologyBiologicalProcessregulation of cilium movement

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

6.15e-0749695GO:0003352
GeneOntologyBiologicalProcessmetal ion transport

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 P2RY12 KCND1 SLC6A16 SLC6A17 SLC22A4 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

8.38e-0710006915GO:0030001
GeneOntologyBiologicalProcessimport across plasma membrane

SLC9A2 SLC12A3 SLC15A2 SLC22A4 TRPV4 LRRC8B SLC2A1 SLC6A14

9.86e-07230698GO:0098739
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC5A11 SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 P2RY12 KCND1 SLC6A16 SLC6A17 SLC22A4 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

9.90e-0711576916GO:0006812
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC26A2 CLN3 SLC6A17 AGTR2 SLCO1B3 LRRC8B SSTR4 SLC13A2 SLC2A1 SLC6A14

1.03e-064106910GO:0046942
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 P2RY12 KCND1 SLC6A16 SLC26A2 SLC6A17 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

1.04e-0610176915GO:0098660
GeneOntologyBiologicalProcessorganic anion transport

SLC26A2 CLN3 SLC6A17 AGTR2 SLCO1B3 LRRC8B SSTR4 SLC13A2 SLCO6A1 SLC2A1 SLC6A14

1.04e-065156911GO:0015711
GeneOntologyBiologicalProcessorganic acid transport

SLC26A2 CLN3 SLC6A17 AGTR2 SLCO1B3 LRRC8B SSTR4 SLC13A2 SLC2A1 SLC6A14

1.08e-064126910GO:0015849
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 P2RY12 KCND1 SLC6A16 SLC6A17 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

1.80e-069226914GO:0098662
GeneOntologyBiologicalProcessvascular process in circulatory system

HTR1D P2RY1 SLC15A2 SLC6A17 AGTR2 TRPV4 TACR2 TACR1 SLC2A1

2.11e-06344699GO:0003018
GeneOntologyBiologicalProcessregulation of flagellated sperm motility

OR4M2 OR4M1 TACR2 TACR1

2.21e-0628694GO:1901317
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC9A2 CATSPER1 SLC12A3 SLC41A3 SLC15A2 P2RY12 KCND1 SLC6A16 SLC6A17 PKD1 KCNK1 TRPV4 SLC13A2 SLC6A14

2.31e-069426914GO:0098655
GeneOntologyBiologicalProcessregulation of microtubule-based movement

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

3.20e-0668695GO:0060632
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

OR4M2 ABCA1 GPR61 OR4M1 GPR101 SSTR4 ADCY7

3.47e-06191697GO:0007189
GeneOntologyBiologicalProcessnegative regulation of norepinephrine secretion

P2RY1 P2RY12 AGTR2

5.80e-0611693GO:0010700
GeneOntologyBiologicalProcesssignal release

ABCA1 HTR1D P2RY1 P2RY12 GPR158 ABCA12 AGTR2 TRPV4 TACR2 TACR1 F2RL2

1.01e-056536911GO:0023061
GeneOntologyBiologicalProcessexport from cell

ABCA1 HTR1D RHBDF1 P2RY1 SLC15A2 P2RY12 GPR158 ABCA12 AGTR2 PKD1 TRPV4 TACR2 TACR1 F2RL2

2.31e-0511536914GO:0140352
GeneOntologyBiologicalProcessneurotransmitter transport

HTR1D P2RY1 GPR158 SLC6A16 SLC6A17 SLC22A4 TACR2

2.52e-05259697GO:0006836
GeneOntologyBiologicalProcessorganic hydroxy compound transport

SLC5A11 ABCA1 P2RY1 P2RY12 ABCA12 AGTR2 SLCO1B3 TMEM97

2.53e-05358698GO:0015850
GeneOntologyBiologicalProcessresponse to vitamin B3

ABCA1 SCAP

3.30e-053692GO:0033552
GeneOntologyBiologicalProcessmonoatomic anion transport

GPR89B SLC12A3 SLC26A2 GPR89A LRRC8B SLC6A14

3.39e-05183696GO:0006820
GeneOntologyBiologicalProcesspositive regulation of reproductive process

OR4M2 P2RY1 OR4M1 TACR2 TACR1

4.72e-05118695GO:2000243
GeneOntologyBiologicalProcessamino acid transport

SLC6A16 CLN3 SLC6A17 SLC22A4 LRRC8B SLC6A14

4.83e-05195696GO:0006865
GeneOntologyBiologicalProcessregulation of microtubule-based process

OR4M2 CATSPER1 PKD1 OR4M1 TRPV4 TACR2 TACR1

5.52e-05293697GO:0032886
GeneOntologyBiologicalProcesspositive regulation of vascular permeability

TRPV4 TACR2 TACR1

6.05e-0523693GO:0043117
GeneOntologyBiologicalProcessnegative regulation of catecholamine secretion

P2RY1 P2RY12 AGTR2

6.05e-0523693GO:0033604
GeneOntologyBiologicalProcessregulation of secretion

HTR1D RHBDF1 P2RY1 P2RY12 GPR158 ABCA12 AGTR2 TACR2 TACR1 SSTR4 F2RL2

6.59e-058016911GO:0051046
GeneOntologyBiologicalProcessamide transport

ABCA1 SLC15A2 ABCA12 CLN3 SLCO1B3 TRPV4 TACR2 F2RL2

7.81e-05420698GO:0042886
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

P2RY1 P2RY12 AGTR2

8.82e-0526693GO:0014061
GeneOntologyBiologicalProcessamine transport

P2RY1 P2RY12 AGTR2 TACR2 SLC6A14

9.60e-05137695GO:0015837
GeneOntologyBiologicalProcessoperant conditioning

TACR2 TACR1

1.10e-045692GO:0035106
GeneOntologyBiologicalProcessnorepinephrine secretion

P2RY1 P2RY12 AGTR2

1.11e-0428693GO:0048243
GeneOntologyBiologicalProcessrenal system process

SLC12A3 SLC15A2 CLN3 AGTR2 TACR1

1.42e-04149695GO:0003014
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GPR89B SLC12A3 SLC26A2 GPR89A LRRC8B

1.61e-04153695GO:0098656
GeneOntologyBiologicalProcessregulation of secretion by cell

HTR1D RHBDF1 P2RY1 P2RY12 GPR158 ABCA12 AGTR2 TACR2 TACR1 F2RL2

1.67e-047406910GO:1903530
GeneOntologyBiologicalProcesssecretion

ABCA1 HTR1D RHBDF1 P2RY1 P2RY12 GPR158 ABCA12 AGTR2 TRPV4 TACR2 TACR1 SSTR4 F2RL2

1.78e-0412216913GO:0046903
GeneOntologyBiologicalProcesssecretion by cell

ABCA1 HTR1D RHBDF1 P2RY1 P2RY12 GPR158 ABCA12 AGTR2 TRPV4 TACR2 TACR1 F2RL2

1.93e-0410646912GO:0032940
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

HTR1D P2RY1 P2RY12 ADCY7

1.98e-0486694GO:0007193
GeneOntologyBiologicalProcesschemical homeostasis

GPR89B OR4M2 ABCA1 SLC9A2 SLC12A3 P2RY1 ABCA12 CLN3 AGTR2 OR4M1 GPR89A TRPV4 TMEM97

2.23e-0412496913GO:0048878
GeneOntologyBiologicalProcesspositive regulation of response to food

OR4M2 OR4M1

2.29e-047692GO:0032097
GeneOntologyBiologicalProcesspositive regulation of appetite

OR4M2 OR4M1

2.29e-047692GO:0032100
GeneOntologyBiologicalProcesscarnitine transmembrane transport

SLC22A4 SLC6A14

2.29e-047692GO:1902603
GeneOntologyBiologicalProcessnorepinephrine transport

P2RY1 P2RY12 AGTR2

2.78e-0438693GO:0015874
GeneOntologyBiologicalProcessregulation of intracellular pH

GPR89B SLC9A2 CLN3 GPR89A

2.79e-0494694GO:0051453
GeneOntologyBiologicalProcesslipid transport

ABCA1 ABCA12 CLN3 AGTR2 SLCO1B3 TMEM97 SSTR4 SLC2A1

2.79e-04506698GO:0006869
GeneOntologyBiologicalProcessdelamination

ABCA12 TRPV4

3.05e-048692GO:0060232
GeneOntologyBiologicalProcesstachykinin receptor signaling pathway

TACR2 TACR1

3.05e-048692GO:0007217
GeneOntologyBiologicalProcesspositive regulation of response to nutrient levels

OR4M2 OR4M1

3.05e-048692GO:0032109
GeneOntologyBiologicalProcessregulation of lipid transport

ABCA1 ABCA12 AGTR2 TMEM97 SSTR4

3.34e-04179695GO:0032368
GeneOntologyBiologicalProcessregulation of cellular pH

GPR89B SLC9A2 CLN3 GPR89A

3.67e-04101694GO:0030641
GeneOntologyBiologicalProcesscell volume homeostasis

SLC12A3 CLN3 TRPV4

3.75e-0442693GO:0006884
GeneOntologyBiologicalProcesspositive regulation of uterine smooth muscle contraction

TACR2 TACR1

3.91e-049692GO:0070474
GeneOntologyBiologicalProcessbrain renin-angiotensin system

AGTR2 TACR1

3.91e-049692GO:0002035
GeneOntologyBiologicalProcesscarnitine transport

SLC22A4 SLC6A14

3.91e-049692GO:0015879
GeneOntologyBiologicalProcessflagellated sperm motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

3.98e-04186695GO:0030317
GeneOntologyBiologicalProcessnegative regulation of amine transport

P2RY1 P2RY12 AGTR2

4.02e-0443693GO:0051953
GeneOntologyBiologicalProcesssperm motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

4.71e-04193695GO:0097722
GeneOntologyBiologicalProcessintestine smooth muscle contraction

HTR1D TACR2

4.88e-0410692GO:0014827
GeneOntologyBiologicalProcesshormone secretion

P2RY1 ABCA12 AGTR2 TRPV4 TACR2 TACR1 F2RL2

5.02e-04420697GO:0046879
GeneOntologyBiologicalProcesslipid localization

ABCA1 ABCA12 CLN3 AGTR2 SLCO1B3 TMEM97 SSTR4 SLC2A1

5.81e-04565698GO:0010876
GeneOntologyBiologicalProcesshormone transport

P2RY1 ABCA12 AGTR2 TRPV4 TACR2 TACR1 F2RL2

5.94e-04432697GO:0009914
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

HTR1D P2RY1 GPR158 TACR2

6.61e-04118694GO:0046928
GeneOntologyBiologicalProcesscilium movement involved in cell motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

6.91e-04210695GO:0060294
GeneOntologyBiologicalProcessamino acid transmembrane transport

CLN3 SLC22A4 LRRC8B SLC6A14

7.04e-04120694GO:0003333
GeneOntologyBiologicalProcessregulation of pH

GPR89B SLC9A2 CLN3 GPR89A

7.04e-04120694GO:0006885
GeneOntologyBiologicalProcessregulation of uterine smooth muscle contraction

TACR2 TACR1

7.12e-0412692GO:0070472
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, cholinergic

TACR2 TACR1

7.12e-0412692GO:0032224
GeneOntologyBiologicalProcesscirculatory system process

HTR1D P2RY1 SLC15A2 SLC6A17 AGTR2 TRPV4 TACR2 TACR1 SLC2A1

7.25e-04733699GO:0003013
GeneOntologyBiologicalProcessintracellular lipid transport

ABCA1 ABCA12 TMEM97

7.45e-0453693GO:0032365
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

RHBDF1 P2RY1 P2RY12 AGTR2 TACR2

7.52e-04214695GO:1903531
GeneOntologyBiologicalProcessregulation of lipid localization

ABCA1 ABCA12 AGTR2 TMEM97 SSTR4

7.68e-04215695GO:1905952
GeneOntologyBiologicalProcesscilium-dependent cell motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

7.68e-04215695GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

OR4M2 CATSPER1 OR4M1 TACR2 TACR1

7.68e-04215695GO:0001539
GeneOntologyBiologicalProcessregulation of amine transport

P2RY1 P2RY12 AGTR2 TACR2

8.20e-04125694GO:0051952
GeneOntologyBiologicalProcessG protein-coupled purinergic receptor signaling pathway

P2RY1 P2RY12

8.40e-0413692GO:0035588
GeneOntologyBiologicalProcessG protein-coupled purinergic nucleotide receptor signaling pathway

P2RY1 P2RY12

8.40e-0413692GO:0035589
GeneOntologyBiologicalProcessuterine smooth muscle contraction

TACR2 TACR1

8.40e-0413692GO:0070471
GeneOntologyBiologicalProcessG protein-coupled adenosine receptor signaling pathway

P2RY1 P2RY12

8.40e-0413692GO:0001973
GeneOntologyBiologicalProcessacetate ester transport

SLC22A4 TACR2

8.40e-0413692GO:1901374
GeneOntologyBiologicalProcessregulation of intracellular lipid transport

ABCA12 TMEM97

8.40e-0413692GO:0032377
GeneOntologyCellularComponentapical plasma membrane

SLC5A11 SLC9A2 SLC12A3 P2RY1 SLC15A2 FZD3 SLC26A2 SLC22A4 KCNK1 TRPV4 SLC13A2 F2RL2 SLC2A1 SLC6A14

5.52e-104876914GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC5A11 SLC9A2 SLC12A3 P2RY1 SLC15A2 FZD3 SLC26A2 SLC22A4 KCNK1 TRPV4 SLC13A2 F2RL2 SLC2A1 SLC6A14

6.75e-095926914GO:0045177
GeneOntologyCellularComponentGolgi membrane

GPR89B CASD1 SCAP RHBDF1 FIG4 ABCA12 CLN3 HHAT PKD1 GPR89A LYSMD3 SLC2A1

3.76e-067216912GO:0000139
GeneOntologyCellularComponentbasal plasma membrane

ABCA1 P2RY1 P2RY12 SLC22A4 PKD1 SLCO1B3 SLCO6A1 SLC2A1

2.13e-05354698GO:0009925
GeneOntologyCellularComponentbasal part of cell

ABCA1 P2RY1 P2RY12 SLC22A4 PKD1 SLCO1B3 SLCO6A1 SLC2A1

3.39e-05378698GO:0045178
GeneOntologyCellularComponentmonoatomic ion channel complex

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A LRRC8B SLCO6A1

3.39e-05378698GO:0034702
GeneOntologyCellularComponenttransporter complex

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A LRRC8B SLCO6A1 SLC2A1

7.88e-05550699GO:1990351
GeneOntologyCellularComponentsperm head

OPN4 TACR2 TACR1

1.31e-0430693GO:0061827
GeneOntologyCellularComponenttransmembrane transporter complex

GPR89B CATSPER1 KCND1 PKD1 KCNK1 GPR89A LRRC8B SLCO6A1

3.19e-04523698GO:1902495
GeneOntologyCellularComponentbasolateral plasma membrane

ABCA1 P2RY1 PKD1 SLCO1B3 SLCO6A1 SLC2A1

6.55e-04320696GO:0016323
GeneOntologyCellularComponentcation channel complex

CATSPER1 KCND1 PKD1 KCNK1 SLCO6A1

1.08e-03235695GO:0034703
GeneOntologyCellularComponentGolgi-associated vesicle membrane

GPR89B PKD1 GPR89A

1.08e-0361693GO:0030660
GeneOntologyCellularComponentCatSper complex

CATSPER1 SLCO6A1

1.10e-0315692GO:0036128
GeneOntologyCellularComponentcalcium channel complex

CATSPER1 PKD1 SLCO6A1

1.81e-0373693GO:0034704
GeneOntologyCellularComponentcell projection membrane

P2RY12 SLC26A2 PKD1 KCNK1 TRPV4 SLC6A14

2.98e-03431696GO:0031253
GeneOntologyCellularComponentcytoplasmic vesicle membrane

GPR89B SCAP GPR61 SLC15A2 FIG4 ABCA12 CLN3 SLC6A17 PKD1 GPR89A RNF13

3.51e-0313076911GO:0030659
GeneOntologyCellularComponentvesicle membrane

GPR89B SCAP GPR61 SLC15A2 FIG4 ABCA12 CLN3 SLC6A17 PKD1 GPR89A RNF13

3.89e-0313256911GO:0012506
DomainGPCR_Rhodpsn_7TM

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R9 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 P2RY1 P2RY12 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4F6 OR1D2

2.18e-176706523IPR017452
DomainG_PROTEIN_RECEP_F1_2

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R9 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 P2RY1 P2RY12 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4F6 OR1D2

4.29e-176916523PS50262
DomainGPCR_Rhodpsn

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 TAS2R9 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 P2RY1 P2RY12 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4F6 OR1D2

4.43e-176926523IPR000276
Domain7tm_1

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 P2RY1 P2RY12 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4F6 OR1D2

4.04e-166776522PF00001
DomainG_PROTEIN_RECEP_F1_1

OR3A1 GPR146 OR12D3 OR4M2 OR51B5 OPN4 HTR1D OR4N2 OR8B4 GPR61 OR12D2 P2RY1 P2RY12 AGTR2 OR4M1 TACR2 TACR1 GPR101 SSTR4 F2RL2 OR4F6 OR1D2

5.16e-166856522PS00237
DomainOlfact_rcpt

OR3A1 OR12D3 OR4M2 OR51B5 OR4N2 OR8B4 OR12D2 OR4M1 OR4F6 OR1D2

9.69e-073936510IPR000725
DomainMFS_dom

SLC15A2 CLN3 SLC22A4 SLCO1B3 SLCO6A1 SLC2A1

7.11e-06134656IPR020846
DomainNA_NEUROTRAN_SYMP_2

SLC6A16 SLC6A17 SLC6A14

3.16e-0518653PS00754
DomainNeurokn_rcpt

TACR2 TACR1

3.57e-053652IPR001681
DomainNA_NEUROTRAN_SYMP_3

SLC6A16 SLC6A17 SLC6A14

3.75e-0519653PS50267
DomainSNF

SLC6A16 SLC6A17 SLC6A14

3.75e-0519653PF00209
DomainNa/ntran_symport

SLC6A16 SLC6A17 SLC6A14

3.75e-0519653IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A16 SLC6A17 SLC6A14

3.75e-0519653PS00610
DomainLYSM

LYSMD4 LYSMD3

1.77e-046652PS51782
DomainLysM

LYSMD4 LYSMD3

1.77e-046652PF01476
Domain-

LYSMD4 LYSMD3

1.77e-0466523.10.350.10
DomainLysM_dom

LYSMD4 LYSMD3

1.77e-046652IPR018392
DomainLysM

LYSMD4 LYSMD3

1.77e-046652SM00257
Domain7TM_GPCR_Srsx

OPN4 HTR1D TACR2 SSTR4

6.26e-04112654SM01381
DomainOA_transporter

SLCO1B3 SLCO6A1

7.70e-0412652IPR004156
DomainABC_A

ABCA1 ABCA12

7.70e-0412652IPR026082
DomainOATP

SLCO1B3 SLCO6A1

7.70e-0412652PF03137
DomainSSD

SCAP PTCHD4

9.08e-0413652PS50156
DomainSSD

SCAP PTCHD4

9.08e-0413652IPR000731
DomainSUGAR_TRANSPORT_1

SLC22A4 SLC2A1

3.13e-0324652PS00216
DomainTAS2R

TAS2R1 TAS2R9

3.67e-0326652PF05296
DomainT2R

TAS2R1 TAS2R9

3.67e-0326652IPR007960
DomainSugar_transporter_CS

SLC22A4 SLC2A1

5.53e-0332652IPR005829
DomainMFS

SLC22A4 SLCO1B3 SLC2A1

6.33e-03108653PS50850
DomainSugar_tr

SLC22A4 SLC2A1

6.96e-0336652PF00083
DomainMFS_sugar_transport-like

SLC22A4 SLC2A1

6.96e-0336652IPR005828
DomainKazal_2

SLCO1B3 SLCO6A1

6.96e-0336652PF07648
DomainIon_trans_dom

CATSPER1 KCND1 TRPV4

7.35e-03114653IPR005821
DomainIon_trans

CATSPER1 KCND1 TRPV4

7.35e-03114653PF00520
DomainABC_transporter_CS

ABCA1 ABCA12

9.39e-0342652IPR017871
DomainABC_TRANSPORTER_2

ABCA1 ABCA12

1.21e-0248652PS50893
DomainABC_tran

ABCA1 ABCA12

1.21e-0248652PF00005
DomainABC_TRANSPORTER_1

ABCA1 ABCA12

1.26e-0249652PS00211
PathwayWP_GPCRS_NONODORANT

TAS2R1 OPN4 HTR1D P2RY1 P2RY12 FZD3 AGTR2 TACR2 TACR1 SSTR4 F2RL2

7.52e-092665711MM15843
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC5A11 ABCA1 SLC9A2 SLC12A3 SLC15A2 ABCA12 SLC26A2 CLN3 SLC22A4 SLCO1B3 TRPV4 LRRC8B SLC13A2 ADCY7 SLC2A1 SLC6A14

2.01e-087365716M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A11 SLC9A2 SLC12A3 SLC15A2 SLC26A2 SLC22A4 SLCO1B3 SLC13A2 SLC2A1 SLC6A14

3.36e-082385710MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A11 SLC9A2 SLC12A3 SLC15A2 SLC26A2 SLC22A4 SLCO1B3 SLC13A2 SLC2A1 SLC6A14

5.14e-082495710M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC5A11 ABCA1 SLC9A2 SLC12A3 SLC15A2 ABCA12 SLC26A2 CLN3 SLC22A4 SLCO1B3 TRPV4 LRRC8B SLC13A2 SLC2A1 SLC6A14

5.18e-086815715MM14985
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR3A1 OR12D3 OPN4 HTR1D P2RY1 P2RY12 AGTR2 SSTR4 F2RL2 OR1D2

7.72e-082605710M39397
PathwayREACTOME_GPCR_LIGAND_BINDING

TAS2R1 TAS2R9 OPN4 HTR1D P2RY1 P2RY12 FZD3 AGTR2 TACR2 TACR1 SSTR4 F2RL2

2.52e-074635712M507
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR3A1 OR12D3 OR4M2 OR51B5 OR5AC1 OR4N2 OR8B4 OR12D2 OR4M1 OR4F6 OR1D2

7.21e-074175711M4072
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OPN4 HTR1D OR8B4 P2RY1 P2RY12 AGTR2 SSTR4 F2RL2

7.52e-07186578MM15994
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR3A1 OR12D3 OR4M2 OR51B5 OR4N2 OR8B4 OR12D2 OR4M1 OR4F6 OR1D2

3.10e-063895710M14091
PathwayREACTOME_SIGNALING_BY_GPCR

TAS2R1 TAS2R9 OPN4 HTR1D P2RY1 P2RY12 FZD3 AGTR2 TACR2 TACR1 SSTR4 F2RL2 ADCY7

3.33e-067025713M746
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OPN4 HTR1D P2RY1 P2RY12 AGTR2 TACR2 TACR1 SSTR4 F2RL2

6.33e-06330579M18334
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

ABCA1 SLC12A3 ABCA12 SLC26A2 SLCO1B3 SLC2A1 SLC6A14

6.80e-06177577M27476
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OPN4 HTR1D P2RY1 P2RY12 AGTR2 TACR2 TACR1 SSTR4 F2RL2

6.81e-06333579MM14963
PathwayREACTOME_SENSORY_PERCEPTION

OR3A1 OR12D3 OR4M2 OR51B5 TAS2R1 OR5AC1 OR4N2 OR8B4 OR12D2 OR4M1 OR4F6 OR1D2

7.02e-066365712M41834
PathwayREACTOME_GPCR_LIGAND_BINDING

TAS2R1 OPN4 HTR1D P2RY1 P2RY12 AGTR2 TACR2 TACR1 SSTR4 F2RL2

7.51e-064305710MM15160
PathwayWP_GPCRS_ODORANT

GPR146 GPR89B GPR61 GPR158 GPR89A GPR101

3.94e-05157576MM15872
PathwayREACTOME_SIGNALING_BY_GPCR

TAS2R1 OPN4 HTR1D P2RY1 P2RY12 AGTR2 TACR2 TACR1 SSTR4 F2RL2 ADCY7

4.62e-056465711MM14962
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC12A3 SLC26A2 SLCO1B3 SLC2A1 SLC6A14

4.84e-0599575M27474
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A2 SLC12A3 SLC15A2 SLC26A2 SLC6A14

7.33e-05108575M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A2 SLC12A3 SLC15A2 SLC26A2 SLC6A14

7.66e-05109575MM15074
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

HTR1D P2RY1 AGTR2 TACR2 TACR1 SSTR4 F2RL2

1.07e-04272577M13380
PathwayREACTOME_TACHYKININ_RECEPTORS_BIND_TACHYKININS

TACR2 TACR1

1.59e-045572M27277
PathwayREACTOME_TACHYKININ_RECEPTORS_BIND_TACHYKININS

TACR2 TACR1

1.59e-045572MM14977
PathwayWP_GPCRS_PEPTIDE

AGTR2 TACR2 TACR1 SSTR4

1.81e-0470574MM15959
PathwayWP_PEPTIDE_GPCRS

AGTR2 TACR2 TACR1 SSTR4

2.36e-0475574M39696
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A11 SLC22A4 SLC13A2 SLC6A14

2.48e-0476574MM15072
PathwayWP_NRF2_PATHWAY

SLC5A11 SLC6A16 SLC6A17 SLC2A1 SLC6A14

2.57e-04141575M39454
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

TAS2R1 TAS2R9 HTR1D P2RY12 AGTR2 SSTR4 ADCY7

2.59e-04314577M600
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A11 SLC22A4 SLC13A2 SLC6A14

3.64e-0484574M27334
PathwayWP_GPCRS_OTHER

OR3A1 GPR146 HTR1D OR1D2

6.05e-0496574MM15939
PathwayREACTOME_P2Y_RECEPTORS

P2RY1 P2RY12

8.63e-0411572MM15049
PathwayREACTOME_P2Y_RECEPTORS

P2RY1 P2RY12

1.03e-0312572M10960
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

TAS2R1 HTR1D P2RY12 AGTR2 SSTR4 ADCY7

1.06e-03289576MM15057
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

AGTR2 TACR2 TACR1 SSTR4 F2RL2

1.18e-03197575M12289
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

AGTR2 TACR2 TACR1 SSTR4 F2RL2

1.18e-03197575MM14970
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

OPN4 P2RY1 TACR2 TACR1 F2RL2

1.56e-03210575MM15043
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC5A11 SLC6A16 SLC26A2 SLC6A17 SLC2A1 SLC6A14

1.63e-03314576M39428
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

OPN4 P2RY1 TACR2 TACR1 F2RL2

1.80e-03217575M18437
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

P2RY1 P2RY12

1.86e-0316572M6786
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

P2RY1 P2RY12

1.86e-0316572MM15050
PathwayWP_GPCRS_ORPHAN

GPR89B GPR89A

2.63e-0319572MM15991
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR3A1 OR12D3 OR4M2 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4F6 OR1D2

7.30e-11340691111875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR3A1 OR12D3 OR4M2 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4F6 OR1D2

7.30e-11340691111802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR3A1 OR12D3 OR4M2 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4F6 OR1D2

8.01e-11343691132295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR3A1 OR12D3 OR4M2 OR5AC1 OR4N2 OR8B4 OR12D2 OR12D1 OR4M1 OR4F6 OR1D2

8.79e-11346691114611657
Pubmed

The human olfactory receptor gene family.

OR3A1 OR12D3 OR4M2 OR51B5 OR5AC1 OR4N2 OR8B4 OR12D2 OR4M1 OR4F6 OR1D2

9.42e-09541691114983052
Pubmed

Activation of platelet function through G protein-coupled receptors.

P2RY1 P2RY12 F2RL2

1.49e-07669317158345
Pubmed

Dissociation of heterotrimeric g proteins in cells.

OPN4 HTR1D P2RY1 P2RY12 AGTR2 SSTR4

1.57e-0617969618577758
Pubmed

Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.

OR12D3 OR12D2 OR12D1

2.11e-061369314506126
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

OPN4 HTR1D P2RY1 P2RY12 AGTR2 SSTR4

2.98e-0620069618240029
Pubmed

Association of genetic variations in neurokinin-2 receptor with enhanced cough sensitivity to capsaicin in chronic cough.

TACR2 TACR1

3.88e-06269216893949
Pubmed

Role for NK(1) and NK(2) receptors in the motor activity in mouse colon.

TACR2 TACR1

3.88e-06269217597603
Pubmed

Dimorphism in the P2Y1 ADP receptor gene is associated with increased platelet activation response to ADP.

P2RY1 P2RY12

3.88e-06269215514209
Pubmed

Effect of P2Y1 and P2Y12 genetic polymorphisms on the ADP-induced platelet aggregation in a Korean population.

P2RY1 P2RY12

3.88e-06269223849096
Pubmed

Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus.

TACR2 TACR1

3.88e-06269215647454
Pubmed

P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.

P2RY1 P2RY12

3.88e-06269215665114
Pubmed

Recurrent major depressive disorder: Imbalance of neurokinin (NK)-1 and NK-2 receptor expression in monocytes.

TACR2 TACR1

3.88e-06269223142211
Pubmed

Population-Specific Associations of Deleterious Rare Variants in Coding Region of P2RY1-P2RY12 Purinergic Receptor Genes in Large-Vessel Ischemic Stroke Patients.

P2RY1 P2RY12

3.88e-06269229232918
Pubmed

Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel.

P2RY1 P2RY12

3.88e-06269216581111
Pubmed

Both the ADP receptors P2Y1 and P2Y12, play a role in controlling shape change in human platelets.

P2RY1 P2RY12

3.88e-06269212623443
Pubmed

Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.

SLC15A2 SLCO1B3

3.88e-06269229234073
Pubmed

Clopidogrel resistance in North Indian patients of coronary artery disease and lack of its association with platelet ADP receptors P2Y1 and P2Y12 gene polymorphisms.

P2RY1 P2RY12

3.88e-06269222721490
Pubmed

GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.

GPR89B GPR89A

3.88e-06269222572823
Pubmed

P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions.

P2RY1 P2RY12

3.88e-06269220473398
Pubmed

P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells.

P2RY1 TRPV4

3.88e-06269226475857
Pubmed

A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation.

P2RY1 P2RY12

3.88e-06269216194206
Pubmed

Role of ADP receptors on platelets in the growth of ovarian cancer.

P2RY1 P2RY12

3.88e-06269228679740
Pubmed

P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease.

P2RY1 P2RY12

3.88e-06269222574824
Pubmed

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation.

P2RY1 P2RY12

3.88e-06269214644082
Pubmed

Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow.

P2RY1 P2RY12

3.88e-06269215284110
Pubmed

Platelet receptor Gene (P2Y12, P2Y1) and platelet glycoprotein Gene (GPIIIa) polymorphisms are associated with antiplatelet drug responsiveness and clinical outcomes after acute minor ischemic stroke.

P2RY1 P2RY12

3.88e-06269228091702
Pubmed

Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.

P2RY1 P2RY12

3.88e-06269215187029
Pubmed

Tachykinin NK1 and NK2 receptors mediate inhibitory vs excitatory motor responses in human isolated corpus cavernosum and spongiosum.

TACR2 TACR1

3.88e-06269211906947
Pubmed

Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation.

P2RY1 P2RY12

3.88e-06269236681816
Pubmed

Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?

P2RY1 P2RY12

3.88e-06269215602005
Pubmed

Nucleoside triphosphates inhibit ADP, collagen, and epinephrine-induced platelet aggregation: role of P2Y₁ and P2Y₁₂ receptors.

P2RY1 P2RY12

3.88e-06269224071464
Pubmed

Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells.

TACR2 TACR1

3.88e-06269226371842
Pubmed

GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

GPR89B GPR89A

3.88e-06269218794847
Pubmed

Identification of a tachykinin NK(2) receptor splice variant and its expression in human and rat tissues.

TACR2 TACR1

3.88e-06269212427486
Pubmed

Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.

P2RY1 P2RY12

3.88e-06269226743169
Pubmed

The Asprosin-OLFR734 hormonal signaling axis modulates male fertility.

OR4M2 OR4M1

1.16e-05369231798959
Pubmed

Autocrine proliferation of neuroblastoma cells is partly mediated through neurokinin receptors: relevance to bone marrow metastasis.

TACR2 TACR1

1.16e-05369215690122
Pubmed

The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.

P2RY1 P2RY12

1.16e-05369222996695
Pubmed

Hemokinin-1 and substance P stimulate production of inflammatory cytokines and chemokines in human colonic mucosa via both NK1 and NK2 tachykinin receptors.

TACR2 TACR1

1.16e-05369232600668
Pubmed

Combined blockade of ADP receptors and PI3-kinase p110β fully prevents platelet and leukocyte activation during hypothermic extracorporeal circulation.

P2RY1 P2RY12

1.16e-05369222701645
Pubmed

Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells and calcium ions.

P2RY1 P2RY12

1.16e-05369215203713
Pubmed

Association of genetic variants in tachykinins pathway genes with colorectal cancer risk.

TACR2 TACR1

1.16e-05369222733436
Pubmed

The Asprosin-OLFR734 module regulates appetitive behaviors.

OR4M2 OR4M1

1.16e-05369232337066
Pubmed

Functional characterisation of hemokinin-1 in mouse uterus.

TACR2 TACR1

1.16e-05369218977217
Pubmed

PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors.

TACR2 TACR1

1.16e-05369212801882
Pubmed

Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function.

P2RY1 P2RY12

1.16e-05369222079667
Pubmed

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.

GPR89B GPR89A

1.16e-05369232220963
Pubmed

Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells.

TACR2 TACR1

1.16e-05369218203813
Pubmed

Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis.

P2RY12 F2RL2

1.16e-05369220930120
Pubmed

Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.

TACR2 TACR1

1.16e-05369228030866
Pubmed

Molecular cloning of the murine substance K and substance P receptor genes.

TACR2 TACR1

1.16e-0536921370937
Pubmed

ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.

P2RY1 P2RY12

1.16e-05369222916275
Pubmed

Expression of the tachykinin receptor mRNAs in healthy human colon.

TACR2 TACR1

1.16e-05369218835556
Pubmed

Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function.

P2RY1 P2RY12

1.16e-05369216804093
Pubmed

Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs.

PKD1 TRPV4

1.16e-05369215858826
Pubmed

ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.

ABCA1 ABCA12

2.32e-05469223931754
Pubmed

Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.

AGTR2 TRPV4

2.32e-05469229976627
Pubmed

Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage.

TACR2 TACR1

2.32e-05469215084523
Pubmed

Expression of Tachykinins and Tachykinin Receptors and Interaction with Kisspeptin in Human Granulosa and Cumulus Cells.

TACR2 TACR1

2.32e-05469227146034
Pubmed

The effect of P2Y-mediated platelet activation on the release of VEGF and endostatin from platelets.

P2RY1 P2RY12

2.32e-05469220063989
Pubmed

Altered expression of the tachykinins substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors in uterine leiomyomata.

TACR2 TACR1

2.32e-05469227456549
Pubmed

Role of protease-activated and ADP receptor subtypes in thrombin generation on human platelets.

P2RY1 P2RY12

2.32e-05469215099288
Pubmed

A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis.

TACR2 TACR1

2.32e-0546927545574
Pubmed

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2.

RNF13 SLC2A1

2.32e-05469234465340
Pubmed

OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.

OR4M2 OR4M1

2.32e-05469231230984
Pubmed

Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice.

GPR89B GPR89A

2.32e-05469231118204
Pubmed

Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction.

SLC15A2 SLC22A4

3.86e-05569212388627
Pubmed

Transgenic mice ectopically expressing HOXA5 in the dorsal spinal cord show structural defects of the cervical spinal cord along with sensory and motor defects of the forelimb.

TACR2 TACR1

3.86e-05569215158076
Pubmed

Pharmacological profile of the novel mammalian tachykinin, hemokinin 1.

TACR2 TACR1

3.86e-05569211786503
Pubmed

Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.

P2RY1 P2RY12

3.86e-05569217673465
Pubmed

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

PKD1 TRPV4

5.79e-05669215692563
Pubmed

A role for tachykinins in female mouse and rat reproductive function.

TACR2 TACR1

5.79e-05669212773411
Pubmed

Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.

P2RY1 P2RY12

5.79e-05669215914557
Pubmed

β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function.

P2RY1 P2RY12

5.79e-05669222318609
Pubmed

Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.

SLC12A3 AGTR2

5.79e-05669217653210
Pubmed

Characterization of the endokinins: human tachykinins with cardiovascular activity.

TACR2 TACR1

5.79e-05669212716968
Pubmed

A role for tachykinins in the regulation of human sperm motility.

TACR2 TACR1

5.79e-05669217437961
Pubmed

Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.

ABCA1 SCAP

5.79e-05669232514064
Pubmed

Personal receptor repertoires: olfaction as a model.

OR8B4 OR12D2 OR12D1

6.00e-053869322908908
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC9A2 SLC12A3 SLCO1B3 SLCO6A1 SLC6A14

6.57e-0521269519521566
Pubmed

Genetics of platelet reactivity in normal, healthy individuals.

P2RY1 P2RY12

8.09e-05769219740098
Pubmed

Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.

P2RY1 KCND1

8.09e-05769225003238
Pubmed

Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.

P2RY1 P2RY12

8.09e-05769221413988
Pubmed

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.

OPN4 ADCY7

8.09e-05769238109525
Pubmed

Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.

GPR89B GPR89A

8.09e-05769216015370
Pubmed

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

AGTR2 TACR2 TACR1

8.71e-054369323597562
Pubmed

Integrative predictive model of coronary artery calcification in atherosclerosis.

ABCA1 SCAP AGTR2 KCNK1 SLC2A1

9.45e-0522969519948975
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR12D2 OR4M2B OR1D2

1.07e-044669332126975
Pubmed

Identification of G protein-coupled receptor genes from the human genome sequence.

GPR61 P2RY12 GPR101

1.07e-044669312044878
Pubmed

Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation.

TACR2 TACR1

1.08e-04869217448763
Pubmed

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

ABCA1 ABCA12

1.08e-04869224293640
Pubmed

Mouse-human orthology relationships in an olfactory receptor gene cluster.

OR3A1 OR1D2

1.08e-04869211170746
Pubmed

Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.

GPR89B CATSPER1 GPR89A

1.14e-044769329617656
Pubmed

RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.

ABCA1 SLC22A4

1.38e-04969222454430
Pubmed

ABCA12 regulates insulin secretion from β-cells.

ABCA1 ABCA12

1.73e-041069232072744
Pubmed

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.

TMEM97 SLC13A2

1.73e-041069211386760
InteractionPTDSS2 interactions

P2RY1 P2RY12 SLC22A4 KCNK1 TACR1

5.71e-0689585int:PTDSS2
InteractionYIPF3 interactions

P2RY1 P2RY12 SLC22A4 KCNK1 GPR89A TACR1

1.55e-05186586int:YIPF3
InteractionNHERF4 interactions

SLC41A3 SLC15A2 SLC22A4

3.35e-0522583int:NHERF4
InteractionTAC4 interactions

TACR2 TACR1

4.87e-054582int:TAC4
InteractionMT-ND1 interactions

P2RY12 SLC22A4 KCNK1 TACR1

5.49e-0572584int:MT-ND1
InteractionTMEM164 interactions

P2RY12 LRRC8B TACR1

1.64e-0437583int:TMEM164
InteractionVKORC1L1 interactions

P2RY1 P2RY12 KCNK1 TACR1

1.90e-0499584int:VKORC1L1
Cytoband6p22.2-p21.31

OR12D2 OR12D1

2.22e-0556926p22.2-p21.31
Cytoband16p12.1

SLC5A11 CLN3

6.53e-042569216p12.1
Cytoband15q26.3

LYSMD4 OR4F6

1.76e-034169215q26.3
CytobandEnsembl 112 genes in cytogenetic band chr3q25

P2RY1 P2RY12 RNF13

2.57e-03180693chr3q25
GeneFamilySolute carriers

SLC5A11 SLC9A2 SLC12A3 SLC41A3 SLC15A2 SLC6A16 SLC26A2 SLC6A17 SLC22A4 SLCO1B3 SLC13A2 SLCO6A1 SLC2A1 SLC6A14

3.13e-113956014752
GeneFamilyOlfactory receptors, family 12

OR12D3 OR12D2 OR12D1

3.47e-083603160
GeneFamilyTachykinin receptors

TACR2 TACR1

3.24e-053602258
GeneFamilyPurinergic receptors P2Y

P2RY1 P2RY12

4.79e-0410602213
GeneFamilyOlfactory receptors, family 4

OR4M2 OR4N2 OR4M1 OR4F6

8.86e-04129604151
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA12

9.61e-0414602805
GeneFamilyG protein-coupled receptors, Class A orphans

GPR146 GPR61 GPR101

2.21e-0378603262
GeneFamilyTaste 2 receptors

TAS2R1 TAS2R9

7.42e-03396021162
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

HTR1D P2RY1 PKD1 TACR1 GPR101

1.44e-0612668544b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A2 ABCA12 SLC26A2 SLC13A2 SLC6A14

7.39e-061766857622f5a8e7320cc7b593141854107ecaf4adff7f
ComputationalGenes in the cancer module 288.

AGTR2 TACR2 TACR1

1.58e-0437313MODULE_288
ComputationalNeighborhood of THRA

ABCA1 SLC13A2 SLC2A1

4.88e-0454313MORF_THRA
Drugsodium

SLC5A11 GPR89B SLC9A2 SLC12A3 SLC15A2 SLC6A16 SLC26A2 CLN3 SLC22A4 AGTR2 PKD1 KCNK1 SLCO1B3 TACR1 SLC13A2 ADCY7 SLC2A1 SLC6A14

1.17e-109446618CID000000923
Drugserotonin

TAS2R1 HTR1D GPR61 P2RY1 P2RY12 SLC6A16 CLN3 TACR1 GPR101 ADCY7 SLC6A14

5.13e-075546611CID000005202
Drugsumatriptan

HTR1D P2RY1 P2RY12 TACR1 ADCY7

3.57e-0680665CID000005358
Drugchloride

SLC5A11 SLC9A2 HTR1D SLC12A3 P2RY1 SLC15A2 SLC6A16 SLC26A2 PKD1 TACR1 SLC13A2 ADCY7 SLC6A14

6.70e-0610296613CID000000312
DrugGR 159897

TACR2 TACR1

8.28e-062662ctd:C092990
Drugpolygodial

TRPV4 TACR2 TACR1

8.28e-0614663CID000072503
DrugGR205171

HTR1D TACR2 TACR1

1.27e-0516663CID000122033
DrugAC1L1F6H

HTR1D P2RY1 P2RY12 TACR2 ADCY7

1.42e-05106665CID000003104
DrugNM-3

P2RY1 AGTR2 TACR2 TACR1

1.83e-0554664CID005493470
Drugmyo-inositol

SLC5A11 CATSPER1 RHBDF1 P2RY1 P2RY12 FIG4 AGTR2 PKD1 TACR2 TACR1 ADCY7

1.96e-058116611CID000000892
DrugGR 64349

HTR1D TACR2 TACR1

2.18e-0519663CID003036081
Drug(N-N'-bis-(2-(1H-indol-3-yl)-ethyl)-N,N'-bis-(3-thiomorpholin-4-yl-propyl)-phthalamide)

TACR2 TACR1

2.48e-053662ctd:C502587
Drugpotassium

SLC5A11 GPR89B SLC9A2 HTR1D CATSPER1 SLC12A3 P2RY1 KCND1 PKD1 KCNK1 TRPV4 ADCY7

2.87e-0510086612CID000000813
DrugSp(1-7)

AGTR2 TACR2 TACR1

3.44e-0522663CID000115322
Drugaganodine

HTR1D TACR2 TACR1

3.95e-0523663CID000176878
Drugnoradrealine

HTR1D CATSPER1 P2RY1 P2RY12 CLN3 AGTR2 PKD1 TACR1 ADCY7

4.03e-05575669CID000000951
DrugLopac-P-178

P2RY1 P2RY12 TACR2 TACR1

4.30e-0567664CID005478935
DrugPolyphenols

HTR1D FZD3 SLCO1B3 TRPV4 TACR1 POMT1 SLC13A2 SLC2A1

4.75e-05452668ctd:D059808
DrugMen10354

TACR2 TACR1

4.95e-054662CID003083370
DrugN-methylbenzamide

TACR2 TACR1

4.95e-054662CID000011954
Drugink 1

HTR1D TACR1

4.95e-054662CID000476801
DrugGTP[S]

OR3A1 HTR1D CATSPER1 P2RY1 AGTR2 PKD1 TACR1 SSTR4 ADCY7

4.99e-05591669CID000001764
DrugPCR 4099

P2RY1 P2RY12 CLN3 AGTR2 ADCY7

5.23e-05139665CID000002806
DrugAC1L1TSE

P2RY1 SLCO1B3 TACR2 TACR1

5.71e-0572664CID000060719
DrugL-733,060

HHAT TACR2 TACR1

5.77e-0526663CID000132846
Drug1 sulfonylurea

PPP1R3A ABCA1 PIGP CLN3 SLC2A1

5.98e-05143665CID011819083
Drug5(G)-TASP

AGTR2 TACR2 TACR1

8.05e-0529663CID000488931
DrugMEN 10627

TACR2 TACR1

8.23e-055662CID005311274
DrugMen11420

TACR2 TACR1

8.23e-055662CID005311275
DrugAC1L51LV

TACR2 TACR1

8.23e-055662CID000196380
DrugS 79-7

OR3A1 OR1D2

8.23e-055662CID002734809
DrugWIN 64821

TACR2 TACR1

8.23e-055662CID000158365
Drug2-(4-nitrophenyl)benzoxazole

TACR2 TACR1

8.23e-055662CID000070047
DrugRPR 100893

TACR2 TACR1

8.23e-055662CID000132961
DrugLyral

OR3A1 OR1D2

8.23e-055662CID000091604
Drugverapamil

ABCA1 CATSPER1 KCND1 ABCA12 SLC22A4 PKD1 KCNK1 ADCY7

8.36e-05490668CID000002520
DrugSpm-SP

TACR2 TACR1

1.23e-046662CID003081857
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

ABCA12 SLC26A2 KCNK1 TMEM97 ADCY7

1.35e-041706651631_UP
Drugglycylsarcosine

SLC9A2 SLC15A2 SLC22A4

1.42e-0435663CID000093131
Drugthiazolidinedione

PPP1R3A ABCA1 SLC12A3 PKD1 SLCO1B3 SLC2A1

1.43e-04274666CID000005437
DrugL-659,837

TACR2 TACR1

1.72e-047662CID006444163
DrugMen 10573

TACR2 TACR1

1.72e-047662CID000196939
DrugMen 10612

TACR2 TACR1

1.72e-047662CID000196940
DrugMen 10456

TACR2 TACR1

1.72e-047662CID000189859
DrugAC1O44I5

TACR2 TACR1

1.72e-047662CID006324620
Druggamma-undecalactone

OR3A1 OR1D2

1.72e-047662CID000007714
DrugGR159897

TACR2 TACR1

1.72e-047662CID003570748
DrugNeurokinin A-oh

TACR2 TACR1

1.72e-047662CID000147040
DrugLY303870

TACR2 TACR1

1.72e-047662CID003086681
DrugU46619

CATSPER1 P2RY1 P2RY12 AGTR2 PKD1 ADCY7

1.77e-04285666CID000005618
DrugNSC7524

HTR1D CATSPER1 PKD1 TACR1 ADCY7

1.86e-04182665CID000005657
DrugC09179

TRPV4 TACR2 TACR1

1.97e-0439663CID000442082
Drugcaffeine

TAS2R1 CATSPER1 P2RY1 P2RY12 AGTR2 PKD1 TMEM97 ADCY7

2.14e-04562668CID000002519
Drug3-isoreserpine

ABCA1 HTR1D ABCA12 CLN3 ADCY7

2.27e-04190665CID000005052
DrugK-Cl

HTR1D SLC12A3 P2RY1 FZD3 CLN3 TACR2 TACR1 ADCY7

2.27e-04567668CID000004873
DrugAC1L1DXE

HTR1D CATSPER1 PKD1 TRPV4 TACR2 TACR1

2.29e-04299666CID000002548
DrugMrs2279

P2RY1 P2RY12

2.29e-048662CID005311301
DrugLom-TK-I

TACR2 TACR1

2.29e-048662CID000195503
DrugAC1L4Z4R

TACR2 TACR1

2.29e-048662CID000194918
DrugBhsar-SP

TACR2 TACR1

2.29e-048662CID000163829
Drugbaclofen

HTR1D CATSPER1 PKD1 TACR1 ADCY7

2.33e-04191665CID000002284
DrugPHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A

ABCA1 SLC41A3 FIG4 CLN3 POMT1

2.33e-041916657086_DN
DrugH526

SLC12A3 SLC15A2 AGTR2 TACR2 TACR1

2.38e-04192665CID000002550
DrugFk 888

TRPV4 TACR2 TACR1

2.46e-0442663CID000107967
DrugPCMBS

SLC9A2 P2RY12 SLC13A2 SLC2A1

2.47e-04105664CID000011136
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

ABCA1 SLC9A2 CASD1 SLC41A3 CLN3

2.62e-041966655540_DN
DrugTerazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; HL60; HT_HG-U133A

PPP1R3A ABCA1 P2RY1 FZD3 SLC6A16

2.62e-041966652530_UP
Drugcopper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A

P2RY1 AGTR2 POMT1 SSTR4 SLC2A1

2.69e-04197665575_UP
DrugDoxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HT_HG-U133A

TAS2R1 SLC12A3 HHAT SSTR4 SLC2A1

2.75e-041986654235_UP
Drugtolbutamide

SLC5A11 PPP1R3A CLN3 ADCY7 SLC2A1

2.75e-04198665CID000005505
Drugtungstate

OPN4 SLC26A2 SLC13A2 ADCY7

2.75e-04108664CID000001152
Druginaperisone

TACR2 TACR1

2.94e-049662CID000065860
Drugbourgeonal

OR3A1 OR1D2

2.94e-049662CID000064832
DrugSp(7-11)

TACR2 TACR1

2.94e-049662CID003084967
DrugKY-234

TACR2 TACR1

2.94e-049662CID000133083
Drugphyllomedusin

TACR2 TACR1

2.94e-049662CID000168489
DrugAC1MIXOF

TACR2 TACR1

2.94e-049662CID003081850
Drugamiloride

SLC9A2 CATSPER1 RHBDF1 SLC12A3 PKD1 TRPV4

3.03e-04315666CID000016230
Drugguanethidine

P2RY1 AGTR2 TACR2 TACR1

3.27e-04113664CID000003518
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

SLC9A2 P2RY1 P2RY12 SLC26A2 SLC13A2

3.30e-04206665CID000040600
Drugbumetanide

SLC5A11 SLC9A2 SLC12A3 SLC15A2 SLC13A2

3.52e-04209665CID000002471
Drugts M

HHAT TACR2 TACR1

3.67e-0448663CID000428025
DrugR396

TACR2 TACR1

3.67e-0410662CID000164286
DrugAC1L2Y4S

TACR2 TACR1

3.67e-0410662CID000130848
DrugUperolein

TACR2 TACR1

3.67e-0410662CID003085088
Drug1-oxacyclohexadecan-2-one

OR3A1 OR1D2

3.67e-0410662CID000235414
DrugP2(+)

OR3A1 OR1D2

3.67e-0410662CID006857575
DrugR 487

TACR2 TACR1

3.67e-0410662CID000131469
DrugNSC186061

HTR1D TACR2 TACR1 ADCY7

3.86e-04118664CID000004163
Drugbeta-Neurokinin

AGTR2 TACR2 TACR1

3.90e-0449663CID000055583
Drughydrochlorothiazide

SLC12A3 SLC26A2 AGTR2 ADCY7

4.11e-04120664CID000003639
Drugcarbonyl cyanide

SLC5A11 SLC26A2 SLC2A1

4.14e-0450663CID000517957
DrugNka-(4-10)

TACR2 TACR1

4.48e-0411662CID000122230
DrugCilazapril

SLC15A2 AGTR2

4.48e-0411662ctd:D017315
DrugCp96

TACR2 TACR1

4.48e-0411662CID000086380
Drugmusk ambrette

OR3A1 OR1D2

4.48e-0411662CID000006753
Drugezlopitant

TACR2 TACR1

4.48e-0411662CID000188927
DrugAC1Q5XN5

TACR2 TACR1

4.48e-0411662CID000190946
DrugD1-G

SLC15A2 SLC22A4

4.48e-0411662CID011171679
DrugMdl 28,564

TACR2 TACR1

4.48e-0411662CID003081745
DiseaseBronchial Diseases

TACR2 TACR1

1.34e-053632C0006261
DiseaseCortical visual impairment

PIGP RNF13

4.47e-055632C4048268
DiseaseVisual Cortex Disorder

PIGP RNF13

4.47e-055632C0234398
DiseaseHereditary Motor and Sensory Neuropathy Type I

FIG4 TRPV4

1.25e-048632C0751036
DiseaseCharcot-Marie-Tooth Disease, Type Ib

FIG4 TRPV4

1.25e-048632C0270912
DiseaseCharcot-Marie-Tooth Disease, Type Ia (disorder)

FIG4 TRPV4

1.25e-048632C0270911
DiseaseRoussy-Levy Syndrome (disorder)

FIG4 TRPV4

1.25e-048632C0205713
Diseasehypoglycemia (is_implicated_in)

PPP1R3A AGTR2

1.25e-048632DOID:9993 (is_implicated_in)
DiseaseCharcot-Marie-Tooth Disease

FIG4 TRPV4

2.92e-0412632C0007959
DiseaseHereditary Motor and Sensory-Neuropathy Type II

FIG4 TRPV4

3.45e-0413632C0270914
Diseasetype 2 diabetes mellitus (is_implicated_in)

PPP1R3A ABCA1 P2RY12 SLC2A1

4.97e-04171634DOID:9352 (is_implicated_in)
DiseaseFeeding difficulties

PIGP RNF13

6.71e-0418632C0232466
Diseaselongitudinal BMI measurement

TAS2R1 P2RY1 HHAT

7.28e-0482633EFO_0005937
DiseaseMultiple Epiphyseal Dysplasia

SLC26A2 TRPV4

8.32e-0420632C0026760
Diseaseobesity (is_implicated_in)

ABCA1 SLC2A1 SLC6A14

9.86e-0491633DOID:9970 (is_implicated_in)
Diseasesystemic mastocytosis

OR51B5 ABCA1

1.30e-0325632MONDO_0016586
Diseasesensory perception of smell

OR51B5 PTCHD4

1.76e-0329632GO_0007608

Protein segments in the cluster

PeptideGeneStartEntry
YIIPILVIYIIIQYF

CATSPER1

646

Q8NEC5
LVPFIALIIAGFVLY

CSMD2

3416

Q7Z408
LIYIIAFFPFIVLVT

ABCA12

1181

Q86UK0
GIIYFTLYLPYVLCV

ABCA1

751

O95477
AIPILYYIIFVIGFL

AGTR2

46

P50052
VPFFLFIVFVVYTLL

ADCY7

126

P51828
PLFLLFLGIYVFTVV

OR8B4

26

Q96RC9
VLFVIFLSFYLFILP

OR4M2B

26

A0A0X1KG70
FYYLPAVYILVFIIG

P2RY1

51

P47900
LIDVVAILPYYIGLL

KCND1

266

Q9NSA2
QLFVVVFAVLYFLLP

GPR61

206

Q9BZJ8
LIVGIITPVFYLLYY

LYSMD3

226

Q7Z3D4
LLIGIVLPVFYLVYF

LYSMD4

226

Q5XG99
PYVFIIFTVLLVLFF

SLC2A1

431

P11166
GSLLLYFPVVILYFE

GPR158

461

Q5T848
LVLGYLLYLVFGAVV

KCNK1

26

O00180
YPAVLVVFIFVLDYL

OR51B5

196

Q9H339
LQPVVFVLFLFAYLV

OR3A1

26

P47881
VVVLVFGPLIFFYIF

OR4F6

246

Q8NGB9
VLFVIFLSFYLFILP

OR4M1

26

Q8NGD0
VLFVIFLSFYLFILP

OR4M2

26

Q8NGB6
LVFVLVLIFYFIILP

OR4N2

26

Q8NGD1
VLIFYFIILPGNFLI

OR4N2

31

Q8NGD1
VGYPLYIYGSIFIVI

FAM205A

11

Q6ZU69
IFIIIFSYVLSLGPY

GPR101

401

Q96P66
LQPFLFVVFLTIYFI

OR12D2

21

P58182
VLFPLLYTVLFFVGL

P2RY12

26

Q9H244
VILFVLIITYVPYFL

LRRC8B

266

Q6P9F7
FILRLAIYILTFPLY

METTL7A

6

Q9H8H3
LQPFFFGIFLIIYLI

OR12D3

21

Q9UGF7
LQPFLFVVFLTIYFI

OR12D1

21

P0DN82
LAFFGFLIPFVLIIY

F2RL2

266

O00254
FLIPFVLIIYCYAAI

F2RL2

271

O00254
IPYFLLFLIFLITVY

PPP1R3A

1076

Q16821
LFYTIIIPLLNPFIY

OR5AC1

276

P0C628
FYVKYLVLFGVPALL

HHAT

296

Q5VTY9
LPLLIIIYCYIFIFR

OPN4

246

Q9UHM6
VIPVVLYLLFFYVHL

POMT1

271

Q9Y6A1
SFFIPIIYILVLGVF

CASD1

401

Q96PB1
PFYIGYFIVSNIRLL

GPR89A

91

B7ZAQ6
PFYIGYFIVSNIRLL

GPR89B

91

P0CG08
VGFVRFLEGYYIVLI

FIG4

96

Q92562
FYIPSVLLIILYGRI

HTR1D

206

P28221
ILYLVPLLVVIGCYF

FZD3

426

Q9NPG1
LVFIGYVVPALATLY

GPR146

191

Q96CH1
YRSYLIVFFVPILLL

SLC13A2

11

Q13183
LVLIFIPLFDFVIYR

SLC15A2

351

Q16348
IPLVTTYIILFAYIY

SCAP

286

Q12770
VLLFIQLVPVDYYFL

SLC22A4

411

Q9H015
ALPVYLLIAIVIGYV

PIGP

81

P57054
LYHLVVIALIYFLPL

TACR2

196

P21452
VVVYPVYLAILFLFR

PKD1

3331

P98161
IFLIPFGFVIISYVL

OR1D2

206

P34982
LFAIVILPIPAYFVY

SLC6A16

666

Q9GZN6
TVLIYFLPLLVIGYA

TACR1

201

P25103
FLPLLVIGYAYTVVG

TACR1

206

P25103
IYVKPFVVILYLIYA

PTCHD4

461

Q6ZW05
FLGLLAGLVVLFYVY

RHBDF1

811

Q96CC6
FSLPLEYYLIPFLII

RNF13

176

O43567
EYYLIPFLIIVGICL

RNF13

181

O43567
FVVYTFLLGFLLPVL

SSTR4

211

P31391
YLVIIGASEFLPIYL

SLCO6A1

396

Q86UG4
IPIILAVLYLFIYIF

SLC5A11

141

Q8WWX8
LVVPGHLIFFYIIYL

SLC41A3

381

Q96GZ6
GFLPSIYLVFLIILY

CLN3

366

Q13286
IYLVFLIILYEGLLG

CLN3

371

Q13286
RFIFLFFILVIGIYP

TAS2R1

256

Q9NYW7
IRVIEPLFVFLYSYL

SLC9A2

306

Q9UBY0
PGIKIFRFVAPLYYI

SLC26A2

576

P50443
IFLLLLIVYYPVFLV

TAS2R9

236

Q9NYW1
ALRFPALVLYIVFIF

SLCO1B3

631

Q9NPD5
IAIGVVLFLLLYVIY

SLC12A3

591

P55017
VYAPYLLIPFILLIF

TMEM97

146

Q5BJF2
GAYLVPYLVLLIIIG

SLC6A17

96

Q9H1V8
YFTALFPYVVLLILL

SLC6A14

266

Q9UN76
YPVVFIILLVTYIIL

TRPV4

691

Q9HBA0