Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	type I interferon receptor binding	IFNA4 IFNA7 IFNA10 IFNA17	9.15e-06	17	162	4	GO:0005132
GeneOntologyMolecularFunction	kinase binding	TOM1L2 IL12RB2 FMR1 WARS1 WWC3 PPP1R12B TNS2 GCKR RGS14 KAT2B LDB3 PTPRF SIPA1L1 SMO LRRC7 CEP152 NBR1 BANK1 TOP2A HTT	1.17e-04	969	162	20	GO:0019900
GeneOntologyMolecularFunction	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	PDE1C PDE1B	1.95e-04	3	162	2	GO:0048101
GeneOntologyMolecularFunction	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	PDE1C PDE1B	1.95e-04	3	162	2	GO:0004117
GeneOntologyMolecularFunction	myosin VI binding	TOM1 LMTK2	1.95e-04	3	162	2	GO:0070853
GeneOntologyMolecularFunction	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	SPO11 TOP2A	3.88e-04	4	162	2	GO:0003918
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	WRNIP1 SPO11 CHD3 ZRANB3 HELB TOP2A	5.99e-04	127	162	6	GO:0008094
GeneOntologyMolecularFunction	kinase inhibitor activity	CDKN1C WARS1 GCKR KAT2B SMO	6.78e-04	86	162	5	GO:0019210
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE1C PDE4A PDE1B	7.21e-04	22	162	3	GO:0004115
GeneOntologyMolecularFunction	protein kinase binding	TOM1L2 IL12RB2 FMR1 WARS1 PPP1R12B TNS2 RGS14 KAT2B LDB3 PTPRF SIPA1L1 SMO LRRC7 CEP152 NBR1 BANK1 TOP2A	7.53e-04	873	162	17	GO:0019901
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	XRN2 WARS1 DHX38 WRNIP1 SPO11 CHD3 VARS2 ZRANB3 HELB MRM3 MBLAC1 PDE12 RNASE10 TOP2A	7.99e-04	645	162	14	GO:0140640
GeneOntologyMolecularFunction	enzyme inhibitor activity	CDKN1C COL7A1 WARS1 PPP1R12B LMTK2 GCKR APOC3 SERPINA6 KAT2B AGT SMO	8.70e-04	435	162	11	GO:0004857
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE1C PDE4A PDE1B	9.36e-04	24	162	3	GO:0047555
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE1C PDE4A PDE1B	1.06e-03	25	162	3	GO:0004114
GeneOntologyMolecularFunction	molecular function inhibitor activity	CDKN1C COL7A1 WARS1 PPP1R12B LMTK2 GCKR APOC3 SERPINA6 KAT2B AGT NFKBIL1 FNIP1 SMO	1.17e-03	596	162	13	GO:0140678
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE1C PDE4A PDE1B	1.33e-03	27	162	3	GO:0004112
GeneOntologyMolecularFunction	ATP-dependent activity	DHX38 WRNIP1 PEX1 SPO11 ABCC9 CHD3 ZRANB3 HELB MDN1 STARD9 TOP2A ABCC10 DYNC1I1	1.53e-03	614	162	13	GO:0140657
GeneOntologyBiologicalProcess	positive regulation of peptidyl-serine phosphorylation of STAT protein	IFNA4 IFNA7 IFNA10 IFNA17	1.88e-05	21	160	4	GO:0033141
GeneOntologyBiologicalProcess	regulation of peptidyl-serine phosphorylation of STAT protein	IFNA4 IFNA7 IFNA10 IFNA17	3.28e-05	24	160	4	GO:0033139
GeneOntologyBiologicalProcess	neuron development	EPHB6 CDKN1C CNTN4 FAT4 ARHGEF28 FMR1 SZT2 PACSIN1 DDR2 APBB1 DOCK10 LMTK2 PLXND1 CUL7 POSTN KAT2B ALMS1 PTPRF SIPA1L1 AGT CAPRIN2 SMO LRRC7 RP1 HTT EPHB1	5.96e-05	1463	160	26	GO:0048666
GeneOntologyBiologicalProcess	ephrin receptor signaling pathway	EPHB6 ARHGEF28 ANKS1B SIPA1L1 EPHB1	6.14e-05	54	160	5	GO:0048013
GeneOntologyBiologicalProcess	serine phosphorylation of STAT protein	IFNA4 IFNA7 IFNA10 IFNA17	6.18e-05	28	160	4	GO:0042501
GeneOntologyBiologicalProcess	microtubule-based process	XRN2 FMR1 KIAA0319L PEX1 CHD3 CUL7 MREG RGS14 KAT2B ALMS1 STARD9 RNASE10 TLE6 TEKT1 TXNDC9 CEP152 RP1 AP3D1 DYNC1I1 HTT NLRP5	7.19e-05	1058	160	21	GO:0007017
GeneOntologyBiologicalProcess	cellular response to virus	FMR1 IFNA4 IFNLR1 IFNA7 IFNA10 IFNA17	7.22e-05	90	160	6	GO:0098586
GeneOntologyBiologicalProcess	response to dsRNA	IFNA4 IFNA7 IFNA10 IFNA17 PDE12	1.29e-04	63	160	5	GO:0043331
GeneOntologyBiologicalProcess	regulation of defense response to virus by host	IFNA4 IFNLR1 IFNA7 IFNA10 IFNA17	1.29e-04	63	160	5	GO:0050691
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	FMR1 PACSIN1 DDR2 APBB1 PLXND1 CUL7 KAT2B PTPRF AGT CAPRIN2 LRRC7 RP1 HTT	1.31e-04	494	160	13	GO:0031346
GeneOntologyBiologicalProcess	positive regulation of peptidyl-serine phosphorylation	IFNA4 IFNA7 IFNA10 IFNA17 AGT FNIP1	1.37e-04	101	160	6	GO:0033138
GeneOntologyBiologicalProcess	neuron projection development	EPHB6 CNTN4 FAT4 ARHGEF28 FMR1 SZT2 PACSIN1 DDR2 APBB1 DOCK10 LMTK2 PLXND1 CUL7 POSTN KAT2B ALMS1 PTPRF SIPA1L1 AGT CAPRIN2 SMO LRRC7 EPHB1	1.50e-04	1285	160	23	GO:0031175
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	2.69e-06	4	165	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	2.69e-06	4	165	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	2.69e-06	4	165	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	2.69e-06	4	165	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	2.69e-06	4	165	3	IPR015753
Domain	-	EPHB6 MANBA GLB1L DDR2 CUL7 SUCO EPHB1	3.69e-06	73	165	7	2.60.120.260
Domain	Interferon	IFNA4 IFNA7 IFNA10 IFNA17	1.28e-05	17	165	4	PF00143
Domain	INTERFERON_A_B_D	IFNA4 IFNA7 IFNA10 IFNA17	1.28e-05	17	165	4	PS00252
Domain	Interferon_alpha/beta/delta	IFNA4 IFNA7 IFNA10 IFNA17	1.28e-05	17	165	4	IPR000471
Domain	IFabd	IFNA4 IFNA7 IFNA10 IFNA17	1.28e-05	17	165	4	SM00076
Domain	Galactose-bd-like	EPHB6 MANBA GLB1L DDR2 CUL7 SUCO EPHB1	1.99e-05	94	165	7	IPR008979
Domain	Ser-Thr/Tyr_kinase_cat_dom	EPHB6 FLT4 DDR2 LMTK2 BMX PRKY EPHB1	2.27e-04	138	165	7	IPR001245
Domain	TOM1	TOM1L2 TOM1	2.31e-04	3	165	2	IPR014645
Domain	PDEase_N	PDE1C PDE1B	2.31e-04	3	165	2	IPR013706
Domain	PDEase_I_N	PDE1C PDE1B	2.31e-04	3	165	2	PF08499
Domain	FN3_dom	EPHB6 CNTN4 IL12RB2 COL7A1 KIAA0319L IFNLR1 PTPRF EPHB1	5.50e-04	209	165	8	IPR003961
Domain	PDEase	PDE1C PDE4A PDE1B	5.91e-04	19	165	3	IPR023088
Domain	PDEase_I	PDE1C PDE4A PDE1B	8.01e-04	21	165	3	PF00233
Domain	PDEASE_I	PDE1C PDE4A PDE1B	8.01e-04	21	165	3	PS00126
Domain	PDEase_CS	PDE1C PDE4A PDE1B	8.01e-04	21	165	3	IPR023174
Domain	-	PDE1C PDE4A PDE1B	9.22e-04	22	165	3	1.10.1300.10
Domain	-	IFNA4 IFNA7 IFNA10 IFNA17	9.86e-04	50	165	4	1.20.1250.10
Domain	Pkinase_Tyr	EPHB6 FLT4 DDR2 LMTK2 BMX EPHB1	1.01e-03	129	165	6	PF07714
Domain	PDEase_catalytic_dom	PDE1C PDE4A PDE1B	1.05e-03	23	165	3	IPR002073
Domain	4_helix_cytokine_core	IFNA4 IFNA7 IFNA10 IFNA17	1.06e-03	51	165	4	IPR012351
Domain	GAT_dom	TOM1L2 TOM1	1.14e-03	6	165	2	IPR004152
Domain	-	TOM1L2 TOM1	1.14e-03	6	165	2	1.20.58.160
Domain	GAT	TOM1L2 TOM1	1.14e-03	6	165	2	PS50909
Domain	GAT	TOM1L2 TOM1	1.14e-03	6	165	2	PF03127
Domain	HD/PDEase_dom	PDE1C PDE4A PDE1B	1.20e-03	24	165	3	IPR003607
Domain	HDc	PDE1C PDE4A PDE1B	1.20e-03	24	165	3	SM00471
Domain	FN3	EPHB6 CNTN4 IL12RB2 COL7A1 KIAA0319L PTPRF EPHB1	1.30e-03	185	165	7	SM00060
Pathway	KEGG_REGULATION_OF_AUTOPHAGY	IFNA4 IFNA7 IFNA10 IFNA17 ATG4C	9.22e-06	35	116	5	M6382
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	9.54e-06	17	116	4	M47564
Pathway	KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.22e-05	18	116	4	M47539
Pathway	WP_INTERFERONMEDIATED_SIGNALING	IFNA4 IFNLR1 IFNA7 IFNA10 IFNA17	1.22e-05	37	116	5	M39785
Pathway	BIOCARTA_IFNA_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.53e-05	19	116	4	MM1571
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.53e-05	19	116	4	M47450
Pathway	KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.90e-05	20	116	4	M47617
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	2.34e-05	21	116	4	M47909
Pathway	KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	2.84e-05	22	116	4	M47897
Pathway	KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	2.84e-05	22	116	4	M47616
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	3.42e-05	23	116	4	M47452
Pathway	REACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING	IFNA4 IFNA7 IFNA10 IFNA17	3.42e-05	23	116	4	MM15634
Pathway	KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	4.07e-05	24	116	4	M47576
Pathway	KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	4.07e-05	24	116	4	M47782
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	4.07e-05	24	116	4	M47908
Pathway	REACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING	IFNA4 IFNA7 IFNA10 IFNA17	5.66e-05	26	116	4	M982
Pathway	BIOCARTA_CYTOKINE_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	7.65e-05	28	116	4	MM1378
Pathway	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	IFNA4 IFNA7 IFNA10 IFNA17	1.01e-04	30	116	4	M936
Pathway	WP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY	IFNA4 IFNA7 IFNA10 IFNA17	1.15e-04	31	116	4	M39897
Pathway	KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.15e-04	31	116	4	M47964
Pathway	BIOCARTA_INFLAM_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.48e-04	33	116	4	MM1379
Pathway	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	IFNA4 IFNA7 IFNA10 IFNA17	1.67e-04	34	116	4	MM15631
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	IFNA4 IFNA7 IFNA10 IFNA17	1.87e-04	35	116	4	M48246
Pathway	WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE	IFNA4 IFNA7 IFNA10 IFNA17	2.87e-04	39	116	4	MM15914
Pathway	BIOCARTA_IL1R_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	3.49e-04	41	116	4	MM1493
Pathway	WP_15Q25_COPY_NUMBER_VARIATION	SYNJ1 SLC28A1 AP3D1 HTT	5.44e-04	46	116	4	M48105
Pathway	KEGG_AUTOIMMUNE_THYROID_DISEASE	IFNA4 IFNA7 IFNA10 IFNA17	8.69e-04	52	116	4	M13103
Pathway	REACTOME_CAM_PDE_1_ACTIVATION	PDE1C PDE1B	9.85e-04	6	116	2	MM14494
Pathway	WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION	PDE1C PDE4A PDE1B PDE12	1.07e-03	55	116	4	M39763
Pathway	KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY	IFNA4 IFNA7 IFNA10 IFNA17	1.07e-03	55	116	4	M11844
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NES STIM2 ARHGEF28 HJURP APBB1 ANKRD26 LMTK2 KIAA1671 RADIL BMX MDN1 ALMS1 SYNJ1 STARD9 SIPA1L1 EIF4B FNIP1 CEP152 SSH2 GAB1 CCDC102A	1.52e-09	861	169	21	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 PDE4A B4GALNT4 SZT2 UBE3B UBR4 KIAA0319L AKNA LMTK2 TTYH3 PLXND1 IFNLR1 ARHGEF10L RADIL MDN1 PTPRF MROH6 SYNJ1 ZNF839 GCN1 AP3D1 ABCC10 HTT	4.81e-09	1105	169	23	35748872
Pubmed	Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses.	IL12RB2 IFNA4 IFNA7 IFNA10 IFNA17	4.93e-09	14	169	5	22815848
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CNTN4 STIM2 ARHGEF28 DHX38 PTDSS1 ANKRD26 TTYH3 VARS2 CUL7 RADIL LDB3 ALMS1 CEP152 SSH2 KLHL18	2.18e-08	493	169	15	15368895
Pubmed	Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	18835032
Pubmed	High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	6444699
Pubmed	Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	10448195
Pubmed	IFN-alpha can both protect against and promote the development of type 1 diabetes.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	19120292
Pubmed	Effect of interferon-alpha on immediate early gene expression of murine cytomegalovirus.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	8389790
Pubmed	The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	3456887
Pubmed	Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	36681180
Pubmed	Type I interferon dependence of plasmacytoid dendritic cell activation and migration.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	15795237
Pubmed	Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	9794439
Pubmed	Recombinant rabies virus expressing IFNα1 enhanced immune responses resulting in its attenuation and stronger immunogenicity.	IFNA4 IFNA7 IFNA10 IFNA17	1.73e-07	11	169	4	25310498
Pubmed	Decoding type I and III interferon signalling during viral infection.	IFNA4 IFNLR1 IFNA7 IFNA10 IFNA17	1.89e-07	27	169	5	30936491
Pubmed	Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	16565497
Pubmed	Regulation of effector and memory T-cell functions by type I interferon.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	21320124
Pubmed	MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	33123150
Pubmed	A novel anti-viral role for STAT3 in IFN-α signalling responses.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	27988795
Pubmed	Evolution of the interferon alpha gene family in eutherian mammals.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	17512142
Pubmed	Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	9425112
Pubmed	IFN-alpha-mediated suppression of low-affinity FC(epsilon) receptors on Peyer's patch lymphocytes and augmentation of soluble CD23: implications for IgE responses.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	8656058
Pubmed	Repression of the murine interferon alpha 11 gene: identification of negatively acting sequences.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	1886773
Pubmed	The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	2572648
Pubmed	Developmental control of IFN-alpha expression in murine embryos.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	7925651
Pubmed	The role of type 1 interferons in coagulation induced by gram-negative bacteria.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	32016282
Pubmed	Multiple pathways of interferon-induced gene expression in murine macrophages.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	7684767
Pubmed	Structure and expression of cloned murine IFN-alpha genes.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	6188104
Pubmed	Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	26277892
Pubmed	Mapping of murine interferon-alpha genes to chromosome 4.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	6689487
Pubmed	Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	18716002
Pubmed	Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	16611902
Pubmed	Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	30967261
Pubmed	Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	22912583
Pubmed	The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	23747509
Pubmed	Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	17434974
Pubmed	Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	18937499
Pubmed	Structure and expression of a new murine interferon-alpha gene: MuIFN-alpha I9.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	3758677
Pubmed	GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	19406830
Pubmed	Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	8245849
Pubmed	AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	22685550
Pubmed	Sequence and expression of a novel murine interferon alpha gene--homology with enhancer elements in the regulatory region of the gene.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	3017340
Pubmed	Interferon-alpha/beta genes are up-regulated in murine brain astrocytes after infection with Theiler's murine encephalomyelitis virus.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	20038206
Pubmed	Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	8304945
Pubmed	The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	11846978
Pubmed	Identification of distal silencing elements in the murine interferon-A11 gene promoter.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	8760352
Pubmed	Behavioral effects of mouse interferons-alpha and -gamma and human interferon-alpha in mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	1422836
Pubmed	Role of interferons in the regulation of cell proliferation, differentiation, and development.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	7530016
Pubmed	Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	17277125
Pubmed	Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	9794206
Pubmed	Isolation and mapping of four new DNA markers from mouse chromosome 4.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	1360280
Pubmed	Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	17451966
Pubmed	Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	25897172
Pubmed	A polymorphic trinucleotide repeat sequence mapping to distal mouse chromosome 4.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	8672140
Pubmed	Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice.	IFNA4 IFNA7 IFNA10 IFNA17	2.58e-07	12	169	4	7601556
Pubmed	Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	12930842
Pubmed	Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	2014240
Pubmed	An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	18005734
Pubmed	Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	12050368
Pubmed	Isolation and bacterial expression of a murine alpha leukocyte interferon gene.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	6094686
Pubmed	Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	2993652
Pubmed	Isolation and characterization of a novel interferon-alpha-encoding gene, IFN-alpha 11, within a murine IFN cluster.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	1655578
Pubmed	Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	2471809
Pubmed	IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	21263073
Pubmed	Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	8438572
Pubmed	Interferon alpha promotes caspase-8 dependent ultraviolet light-mediated keratinocyte apoptosis via interferon regulatory factor 1.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	38660315
Pubmed	Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	9343822
Pubmed	Evidence for a different susceptibility of primate lentiviruses to type I interferons.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	23255800
Pubmed	Distinction of mouse interferon-alpha subtypes by polymerase chain reaction utilizing consensus primers and type-specific oligonucleotide probes.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	7523540
Pubmed	Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	19635904
Pubmed	Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	19706714
Pubmed	Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	23804712
Pubmed	Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	22431588
Pubmed	Mouse interferon alpha and beta genes are linked at the centromere proximal region of chromosome 4.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	3973562
Pubmed	Organization, structure and expression of murine interferon alpha genes.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	2987810
Pubmed	Anti-retroviral effects of type I IFN subtypes in vivo.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	19130550
Pubmed	Type I IFN protects against antigen-induced arthritis.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	21469099
Pubmed	HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	22739040
Pubmed	Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	20065291
Pubmed	Effects of IFN alpha on late stages of HIV-1 replication cycle.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	9865497
Pubmed	Obstruction of HIV-1 particle release by interferon-alpha occurs before viral protease processing and is independent of envelope glycoprotein.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	9181467
Pubmed	Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	17723216
Pubmed	Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	20427526
Pubmed	Sequencing and bacterial expression of a novel murine alpha interferon gene.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	18726328
Pubmed	Distinct signature type I interferon responses are determined by the infecting virus and the target cell.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	18572754
Pubmed	Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.	IFNA4 IFNA7 IFNA10 IFNA17	3.72e-07	13	169	4	15723075
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	4.49e-07	4	169	3	22419166
Pubmed	Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	18981154
Pubmed	Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	8668211
Pubmed	Regulation of inflammatory monocyte/macrophage recruitment from the bone marrow during murine cytomegalovirus infection: role for type I interferons in localized induction of CCR2 ligands.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	19620305
Pubmed	Interferon induction by HIV glycoprotein 120: role of the V3 loop.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	7526537
Pubmed	Exogenous HIV-1 Vpr disrupts IFN-alpha response by plasmacytoid dendritic cells (pDCs) and subsequent pDC/NK interplay.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	19559726
Pubmed	Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	15240719
Pubmed	Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	16418394
Pubmed	APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	18272764
Pubmed	Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	11884139
Pubmed	Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	19004943
Pubmed	Differential constitutive expression of interferon genes in early mouse embryos.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	7654369
Pubmed	Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	2552026
Pubmed	Modulation of interferon-mediated inhibition of human immunodeficiency virus type 1 by Tat.	IFNA4 IFNA7 IFNA10 IFNA17	5.19e-07	14	169	4	7532202
Cytoband	9p22	IFNA4 IFNA7 IFNA10 IFNA17	2.11e-06	25	169	4	9p22
Cytoband	17q21.31	LRRC37A2 LRRC37A NBR1 SPPL2C	2.48e-04	82	169	4	17q21.31
GeneFamily	Interferons	IFNA4 IFNA7 IFNA10 IFNA17	3.04e-05	32	102	4	598
GeneFamily	Fibronectin type III domain containing	EPHB6 CNTN4 IL12RB2 COL7A1 PTPRF EPHB1	2.92e-04	160	102	6	555
GeneFamily	Phosphodiesterases	PDE1C PDE4A PDE1B	3.24e-04	24	102	3	681
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT4 DDR2 LMTK2	1.48e-03	40	102	3	321
GeneFamily	Sterile alpha motif domain containing	EPHB6 STIM2 ANKS1B EPHB1	1.55e-03	88	102	4	760
GeneFamily	PDZ domain containing	RADIL LDB3 SIPA1L1 LRRC7 FRMPD2B	1.70e-03	152	102	5	1220
GeneFamily	ATP binding cassette subfamily C	ABCC9 ABCC10	2.36e-03	13	102	2	807
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB6 EPHB1	2.74e-03	14	102	2	1095
GeneFamily	AAA ATPases	WRNIP1 PEX1 MDN1	3.33e-03	53	102	3	413
GeneFamily	Aminoacyl tRNA synthetases, Class I	WARS1 VARS2	5.06e-03	19	102	2	131
GeneFamily	Regulators of G-protein signaling	RGS14 RGS8	6.17e-03	21	102	2	720
Coexpression	LEE_CALORIE_RESTRICTION_NEOCORTEX_DN	DDR2 SERPINA6 IFNA4 IFNA7 IFNA10 IFNA17	1.89e-05	85	169	6	MM684
Coexpression	MIKKELSEN_MEF_LCP_WITH_H3K4ME3	WARS1 AKNA TNS2 KIAA1671 POSTN LDB3 RNASE10	2.01e-05	128	169	7	M1966
Coexpression	FAN_EMBRYONIC_CTX_OLIG	TOM1L2 CDKN1C APBB1 ANKS1B DOCK10 TNS2 AGPS LDB3 FNIP1 ATG4C TXNDC9 SSH2 QDPR NBR1 FAM131B GAB1	3.21e-05	754	169	16	M39037
Coexpression	GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	CADM3 PDE1C DDR2 APBB1 TMEM179B SLC28A1 GAS8-AS1 DYNC1I1	3.27e-05	189	169	8	M7266
Coexpression	SHIN_B_CELL_LYMPHOMA_CLUSTER_5	IFNA4 IFNA7 IFNA10 IFNA17	3.49e-05	29	169	4	MM586
Coexpression	MIKKELSEN_MEF_LCP_WITH_H3K4ME3	WARS1 AKNA TNS2 KIAA1671 POSTN LDB3 RNASE10	3.92e-05	142	169	7	MM840
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP	CDKN1C MANBA ANK1 PPP1R12B APBB1 PLXND1 RGS14 GAB1	4.71e-05	199	169	8	M8390
Coexpression	GSE360_DC_VS_MAC_L_MAJOR_DN	FLT4 PPP1R12B PLXND1 CHRNA5 MDN1 ENPEP FAM131B DYNC1I1	4.71e-05	199	169	8	M5182
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP	COL7A1 TAF1B APOC3 CUL7 RGS14 BMX SUCO ABCC10	4.71e-05	199	169	8	M5213
Coexpression	ZHONG_PFC_C3_ASTROCYTE	TOM1L2 CNTN4 PDE1C B4GALNT4 FMR1 VARS2 MDN1 LRRC7 GCN1 FAM131B DYNC1I1	4.76e-05	389	169	11	M39102
Coexpression	GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN	ANK1 PPP1R12B APBB1 ABCC9 LCT RGS14 LDB3 GAB1	4.88e-05	200	169	8	M8398
Coexpression	GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	STIM2 B4GALNT4 FMR1 AKNA APOC3 ZRANB3 MREG TEKT1	4.88e-05	200	169	8	M6537
Coexpression	GSE7831_1H_VS_4H_CPG_STIM_PDC_UP	TOM1L2 APBB1 SPO11 BMX C11orf68 FADS2 TMEM143 NBR1	4.88e-05	200	169	8	M6960
Coexpression	GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN	STIM2 SZT2 ZFPL1 MRM3 RGS14 NFKBIL1 SNAPC3	9.02e-05	162	169	7	M8827
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	CNTN4 ARHGEF28 ZC3H13 ANKS1B ANKRD26 SIPA1L1 SLC28A1 ENPEP	9.82e-05	221	169	8	M39222
Coexpression	ERWIN_COHEN_PBMC_TC_83_AGE_18_45YO_NAIVE_NOT_PREVIOUSLY_IMMUNIZED_24HR_DEG_CANONICAL_PATHWAY_MEMBERS_UP	IFNA4 IFNA7 IFNA10 IFNA17	1.15e-04	39	169	4	M41095
Coexpression	LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP	LRRC66 COL7A1 ANKS1B PTPRF SMO	1.18e-04	74	169	5	M515
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CADM3 B4GALNT4 PDE1B PACSIN1 RGS8 SYNJ1 LRRC7 DYNC1I1	5.80e-07	186	169	8	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKN1C FLT4 WRNIP1 TTYH3 PLXND1 STARD9 PDGFD STON2	8.95e-07	197	169	8	789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 B4GALNT4 LRRC37A3 CCDC168 BMX STON2 EPHB1	3.42e-06	166	169	7	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 B4GALNT4 LRRC37A3 CCDC168 BMX STON2 EPHB1	3.42e-06	166	169	7	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	droplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 KIAA1549 ZRANB3 LRRC27 TOP2A ABCC10 NLRP5	3.56e-06	167	169	7	bad33497ceeab968a7eb8a48b921c6f936390743
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 FAT4 FLT4 APBB1 ARHGEF10L CAPRIN2 NLRP5	3.56e-06	167	169	7	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 RADIL BMX USHBP1 STON2 TDRD10 EPHB1	6.50e-06	183	169	7	38a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C ARHGEF28 PLXND1 KIAA1671 BMX FADS2 EPHB1	7.22e-06	186	169	7	1e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SLC7A13 ANKS1B KIAA1549 TTYH3 SLC28A1 ENPEP	7.22e-06	186	169	7	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	CNTN4 NES COL7A1 DDR2 TNS2 LDB3 STARD9	7.48e-06	187	169	7	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	IL12RB2 DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	7.48e-06	187	169	7	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	IL12RB2 DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	8.30e-06	190	169	7	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 WARS1 PLXND1 RADIL BMX USHBP1 STON2	8.30e-06	190	169	7	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	IL12RB2 DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	8.59e-06	191	169	7	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	IL12RB2 DOCK10 AKNA UBASH3A KAT2B TOP2A MYBL1	8.59e-06	191	169	7	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB2 DOCK10 AKNA CCDC168 PDGFD PLCB2 MYBL1	1.12e-05	199	169	7	598937913fe1f12d741fa49e23ae195a7be5cbe3
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 PDE1C SERPINA6 UBASH3A RGS8 ALMS1	3.75e-05	163	169	6	385b24e18df5ef92108483de312d6c85a1e6d145
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 PDE1C SERPINA6 UBASH3A RGS8 ALMS1	3.75e-05	163	169	6	8004cc0b3428be08b89957b563cd8799f822d931
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|metastatic_Brain / Location, Cell class and cell subclass	PACSIN1 GCKR FAM186B LRRC37A CEP152 EPHB1	3.88e-05	164	169	6	06db4cc064f0765c481ce880207823872c27bfa9
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL7A1 FAT4 PDE1C INSYN1 TNS2 POSTN	4.59e-05	169	169	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL7A1 PDE4A PLXND1 TLE6 LRRC7	5.22e-05	173	169	6	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	CNTN4 NES LRRC66 DDR2 MBLAC1 LDB3	5.22e-05	173	169	6	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL7A1 PDE4A PLXND1 TLE6 LRRC7	5.22e-05	173	169	6	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL7A1 PDE4A PLXND1 TLE6 LRRC7	5.39e-05	174	169	6	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 ANKS1B UBASH3A FAM186B LDB3 DYNC1I1	5.39e-05	174	169	6	ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL7A1 CHD3 TTYH3 OTOF SMO TOP2A	5.39e-05	174	169	6	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL7A1 PDE4A PLXND1 TLE6 LRRC7	5.39e-05	174	169	6	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FOXR1 FLT4 KIAA1671 POSTN PDGFD TDRD10	5.75e-05	176	169	6	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C FAT4 ANK1 DOCK10 RGS8 AGT	5.93e-05	177	169	6	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXR1 PDE1B DOCK10 OTOF PLCB2 CEP152	6.12e-05	178	169	6	8c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB2 PDE4A DOCK10 UBASH3A PDGFD BANK1	6.31e-05	179	169	6	de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB2 PDE4A DOCK10 UBASH3A PDGFD BANK1	6.31e-05	179	169	6	def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SLC7A13 ANKS1B KIAA1549 SLC28A1 ENPEP	6.31e-05	179	169	6	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C ANK1 MREG LDB3 COQ9 DYNC1I1	6.71e-05	181	169	6	09a574a3257e25c8b05a2ab20623a6b07331411a
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C ANK1 MREG LDB3 COQ9 DYNC1I1	6.71e-05	181	169	6	ac4142aa93706b7067f63d2d38e2456859e60768
ToppCell	Adult-Immune-natural_killer_cell-D231\|Adult / Lineage, Cell type, age group and donor	IL12RB2 AKNA KAT2B PDGFD FAM131B MYBL1	6.92e-05	182	169	6	dbf47bf4754d8ec3bc3ab1d5be7a6c47a7afbf43
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 RADIL BMX USHBP1 STON2 EPHB1	7.13e-05	183	169	6	764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 CDKN1C RADIL AGT RNASE10 DYNC1I1	7.13e-05	183	169	6	b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCell	droplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 CDKN1C RADIL AGT RNASE10 DYNC1I1	7.13e-05	183	169	6	19e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 ANKS1B KIAA1549 TTYH3 SLC28A1 ENPEP	7.35e-05	184	169	6	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 SLC7A13 ANKS1B KIAA1549 SLC28A1 ENPEP	7.35e-05	184	169	6	9434731f651820b05335085582960f08fbf895de
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB6 CADM3 ZRANB3 IFNLR1 POSTN RASGEF1C	7.57e-05	185	169	6	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 KIAA1671 RADIL STON2 TDRD10 EPHB1	7.57e-05	185	169	6	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 PLXND1 BMX USHBP1 STON2 EPHB1	7.57e-05	185	169	6	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 HJURP MAGEE2 ZRANB3 MDN1 STON2	7.57e-05	185	169	6	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	(5)_Pericytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PDE1B PPP1R12B DOCK10 POSTN LDB3 ENPEP	7.80e-05	186	169	6	acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell	(5)_Pericytes-(50)_Pericytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	PDE1B PPP1R12B DOCK10 POSTN LDB3 ENPEP	7.80e-05	186	169	6	67b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	7.80e-05	186	169	6	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLT4 ARHGEF28 PLXND1 KIAA1671 STON2 TDRD10	7.80e-05	186	169	6	86b218a400f9c64f92b050f00b49f09647b17437
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLT4 ARHGEF28 PLXND1 KIAA1671 STON2 TDRD10	7.80e-05	186	169	6	f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	7.80e-05	186	169	6	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CDKN1C NES FAT4 POSTN BMX CAPRIN2	8.03e-05	187	169	6	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 KIAA1549 TTYH3 STON2 SLC28A1 ENPEP	8.03e-05	187	169	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1B DOCK10 KIAA1549 TNS2 POSTN STARD9	8.03e-05	187	169	6	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 ARHGEF28 PLXND1 KIAA1671 USHBP1 TDRD10	8.03e-05	187	169	6	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1B DOCK10 KIAA1549 TNS2 POSTN STARD9	8.03e-05	187	169	6	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 ANKS1B KIAA1549 TTYH3 SLC28A1 ENPEP	8.27e-05	188	169	6	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 ANKS1B KIAA1549 TTYH3 SLC28A1 ENPEP	8.27e-05	188	169	6	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C ABCC9 RADIL AGT RNASE10 DYNC1I1	8.52e-05	189	169	6	cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C ABCC9 RADIL AGT RNASE10 DYNC1I1	8.52e-05	189	169	6	102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APBB1 LMTK2 TNS2 POSTN SUCO EPHB1	8.52e-05	189	169	6	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 NES FLT4 PLXND1 PDGFD GAB1	8.52e-05	189	169	6	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	IL12RB2 DOCK10 AKNA KAT2B PDGFD MYBL1	8.52e-05	189	169	6	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C ABCC9 RADIL AGT RNASE10 DYNC1I1	8.52e-05	189	169	6	6e83bf855d4771885b60bb8992df2f9b508eef97
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B ANKS1B ABCC9 LDB3 LRRC7 DYNC1I1	8.77e-05	190	169	6	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 ABCC9 FAM186B MDN1 TLE6	8.77e-05	190	169	6	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 PLXND1 RADIL BMX USHBP1 STON2	8.77e-05	190	169	6	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 DDR2 ABCC9 FAM186B MDN1 TLE6	8.77e-05	190	169	6	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	IL12RB2 PDE1C APBB1 UBASH3A PDGFD MYBL1	8.77e-05	190	169	6	251d50a77e5118a9ad19ea01a7c7c862230ed63c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B ANKS1B ABCC9 LDB3 LRRC7 DYNC1I1	8.77e-05	190	169	6	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL12RB2 DOCK10 AKNA UBASH3A HELB KAT2B	9.02e-05	191	169	6	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C DDR2 ABCC9 POSTN AGT FAM131B	9.02e-05	191	169	6	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	IL12RB2 DOCK10 AKNA UBASH3A HELB KAT2B	9.02e-05	191	169	6	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 PLXND1 BMX USHBP1 STON2 EPHB1	9.29e-05	192	169	6	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	facs-Thymus-Epithelium-24m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 NES TNS2 KIAA1671 USHBP1 PDGFD	9.29e-05	192	169	6	39afea574725ce0c67afdd79facdb34f819a828d
ToppCell	facs-Thymus-Epithelium-24m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 NES TNS2 KIAA1671 USHBP1 PDGFD	9.29e-05	192	169	6	597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCell	facs-Thymus-Epithelium-24m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 NES TNS2 KIAA1671 USHBP1 PDGFD	9.29e-05	192	169	6	bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 PLXND1 BMX USHBP1 STON2 EPHB1	9.29e-05	192	169	6	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C FAT4 FLT4 PLXND1 USHBP1 PDGFD	9.55e-05	193	169	6	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C FAT4 FLT4 PLXND1 USHBP1 PDGFD	9.55e-05	193	169	6	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C FAT4 FLT4 PLXND1 USHBP1 PDGFD	9.55e-05	193	169	6	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	Adult-Immune-T_lymphocyte\|Adult / Lineage, Cell type, age group and donor	IL12RB2 DOCK10 AKNA UBASH3A KAT2B MYBL1	9.55e-05	193	169	6	26df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCell	COVID-19-lung-CD8+_T_cells\|lung / Disease (COVID-19 only), tissue and cell type	IL12RB2 DOCK10 AKNA UBASH3A HELB MYBL1	9.55e-05	193	169	6	780e23e2705fc5c1b70e37568b79731ced5038bd
ToppCell	COVID-19-kidney-T-cells-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL12RB2 DOCK10 AKNA UBASH3A HELB MYBL1	9.55e-05	193	169	6	5b84fa640cf30dea55fde53b810f850ff946d253
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK10 AKNA UBASH3A HELB KAT2B MYBL1	9.83e-05	194	169	6	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	Adult-Immune-T_lymphocyte-D231\|Adult / Lineage, Cell type, age group and donor	IL12RB2 DOCK10 AKNA UBASH3A KAT2B MYBL1	9.83e-05	194	169	6	5c1dca33f382f37a7deb23e573578343c3b54986
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKNA MDN1 KLHL8 DCUN1D3 PRKY MYBL1	1.01e-04	195	169	6	83c125223e7ca0f08a31414b3a16347912564765
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B DDR2 POSTN LDB3 LRRC7 DYNC1I1	1.04e-04	196	169	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	ASK454-Endothelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	NES FAT4 FLT4 PLXND1 POSTN USHBP1	1.04e-04	196	169	6	14dd6956ef420b660be0baf52a66960e57d75d16
ToppCell	ASK454-Endothelial-Endothelium\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	NES FAT4 FLT4 PLXND1 POSTN USHBP1	1.04e-04	196	169	6	2b777a2026b56839112fd179f2db482c49f4594a
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWA5B2 FOXR1 PDE1C POSTN PDGFD FAM131B	1.04e-04	196	169	6	72b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B DDR2 POSTN LDB3 LRRC7 DYNC1I1	1.04e-04	196	169	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTN4 NES GCM2 DDR2 LDB3 STARD9	1.07e-04	197	169	6	f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 WARS1 PLXND1 KIAA1671 STARD9 TDRD10	1.07e-04	197	169	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTN4 FAT4 WARS1 TNS2 POSTN PDGFD	1.07e-04	197	169	6	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	3'-Adult-SmallIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APOC3 LCT POSTN SLC28A1 ENPEP BANK1	1.07e-04	197	169	6	1614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTN4 NES GCM2 DDR2 LDB3 STARD9	1.07e-04	197	169	6	41dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 WARS1 PLXND1 KIAA1671 STARD9 TDRD10	1.07e-04	197	169	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ZC3H13 ANKRD26 CAPRIN2 CEP152 PRRC2A TOP2A	1.07e-04	197	169	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C PDE1C APBB1 ANKS1B LDB3 QDPR	1.10e-04	198	169	6	bdabdb11217ea16e5863aa6bfb0f04d48b17f81e
Drug	Yfrkd	IFNA4 IFNA7 IFNA10 IFNA17	9.84e-08	7	168	4	CID000129984
Drug	bromcresol green	IL12RB2 DDR2 F11 IFNA4 IFNA7 IFNA10 IFNA17 AGT NFKBIL1	1.28e-07	110	168	9	CID000006451
Drug	1hiv	IFNA4 IFNA7 IFNA10 IFNA17	1.96e-07	8	168	4	CID005479205
Drug	Chebi:36708	IFNA4 IFNA7 IFNA10 IFNA17	1.96e-07	8	168	4	CID011966289
Drug	pipobroman	IFNA4 IFNA7 IFNA10 IFNA17	5.80e-07	10	168	4	CID000004842
Drug	flesinoxan	IFNA4 IFNA7 IFNA10 IFNA17	9.07e-07	11	168	4	CID000057347
Drug	barium iodide	IFNA4 IFNA7 IFNA10	1.57e-06	4	168	3	CID000083684
Drug	R 842	IFNA4 IFNA7 IFNA10 IFNA17	1.94e-06	13	168	4	CID000130714
Drug	AC1O52EF	IFNA4 IFNA7 IFNA10 IFNA17	1.94e-06	13	168	4	CID006450817
Drug	DTIC	PDE1C PDE4A PDE1B IFNA4 IFNA7 IFNA10 IFNA17	2.31e-06	81	168	7	CID005281007
Drug	Lanicemine	IFNA4 IFNA7 IFNA10 IFNA17	2.70e-06	14	168	4	CID003038485
Drug	gunacin	IFNA4 IFNA7 IFNA10 IFNA17	2.70e-06	14	168	4	CID000198547
Drug	CHEMBL466993	IFNA4 IFNA7 IFNA10 IFNA17 QDPR	3.53e-06	32	168	5	CID005320808
Drug	pppA2'-5'A2'-5'A	IFNA4 IFNA7 IFNA10 IFNA17	3.66e-06	15	168	4	CID000125229
Drug	B132	IFNA4 IFNA7 IFNA10	3.90e-06	5	168	3	CID002734031
Drug	YNK01	IFNA4 IFNA7 IFNA10 IFNA17	6.32e-06	17	168	4	CID000084071
Drug	HCV-371	IFNA4 IFNA7 IFNA10	7.77e-06	6	168	3	CID003013096
Drug	p203	IFNA4 IFNA7 IFNA10 IFNA17	8.07e-06	18	168	4	CID000019228
Drug	podophyllin	IFNA4 IFNA7 IFNA10 IFNA17	8.07e-06	18	168	4	CID011979494
Drug	Nyco	IFNA4 IFNA7 IFNA10 IFNA17	8.07e-06	18	168	4	CID000071618
Drug	isofagomine lactam	MANBA IFNA4 IFNA7 IFNA10 IFNA17	9.68e-06	39	168	5	CID000448980
Drug	Ciluprevir [USAN]	IFNA4 IFNA7 IFNA10 IFNA17	1.26e-05	20	168	4	CID006450803
Drug	val-mCyd	IFNA4 IFNA7 IFNA10 IFNA17	1.26e-05	20	168	4	CID006918726
Drug	L DO	IFNA4 IFNA7 IFNA10 IFNA17	1.55e-05	21	168	4	CID000097725
Drug	Murabutida	IFNA4 IFNA7 IFNA10 IFNA17 ENPEP	1.58e-05	43	168	5	CID005362018
Drug	WY-14643; Down 200; 100uM; MCF7; HG-U133A	CDKN1C SZT2 APBB1 ABCC9 F11 POSTN LDB3 SNAPC3 GAB1	1.70e-05	198	168	9	368_DN
Drug	Solanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A	PDE1C MANBA PEX1 ABCC9 PLXND1 ZFPL1 PDE12 SYNJ1 GAB1	1.77e-05	199	168	9	4087_DN
Drug	formosanin C	IFNA4 IFNA7 IFNA10 IFNA17	1.89e-05	22	168	4	CID000073597
Drug	AC1LAD6M	IFNA4 IFNA7 IFNA10	2.15e-05	8	168	3	CID000511663
Drug	O4-[3-[(1S)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxyphenyl)-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] O1-[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (Z)-2-chlorobut-2-enedioate	IFNA4 IFNA7 IFNA10	2.15e-05	8	168	3	CID010011375
Drug	AC1L9AL3	IL12RB2 IFNA4 IFNA7 IFNA10 IFNA17	2.21e-05	46	168	5	CID000441122
Drug	Hiltonol	IFNA4 IFNA7 IFNA10 IFNA17	2.27e-05	23	168	4	CID000431963
Drug	AC1L1ZCT	IFNA4 IFNA7 IFNA10 IFNA17	2.71e-05	24	168	4	CID000038235
Drug	cycloferon	IFNA4 IFNA7 IFNA10 IFNA17	2.71e-05	24	168	4	CID000038072
Drug	NSC289637	IFNA4 IFNA7 IFNA10 IFNA17 SLC28A1	2.73e-05	48	168	5	CID000004213
Drug	hycanthone	IFNA4 IFNA7 IFNA10 IFNA17	3.21e-05	25	168	4	CID000003634
Drug	LB80380	IFNA4 IFNA7 IFNA10 IFNA17	3.21e-05	25	168	4	CID006480442
Drug	Telaprevir	IFNA4 IFNA7 IFNA10	3.21e-05	9	168	3	CID003010818
Drug	boceprevir	IFNA4 IFNA7 IFNA10	3.21e-05	9	168	3	CID010324367
Drug	ABMP	IFNA4 IFNA7 IFNA10 IFNA17	3.77e-05	26	168	4	CID000080567
Drug	famciclovir	IFNA4 IFNA7 IFNA10 IFNA17 EIF4B	4.05e-05	52	168	5	CID000003324
Drug	inosiplex	IFNA4 IFNA7 IFNA10 IFNA17	4.40e-05	27	168	4	CID000037510
Drug	VX-497	IFNA4 IFNA7 IFNA10 IFNA17	4.40e-05	27	168	4	CID000153241
Drug	AC1NRD2B	IFNA4 IFNA7 IFNA10 IFNA17	5.10e-05	28	168	4	CID005289317
Drug	NSC229609	LCT SUOX	5.41e-05	2	168	2	CID000069530
Drug	NSC141633	IFNA4 IFNA7 IFNA10 IFNA17	5.88e-05	29	168	4	CID000003628
Drug	NM 108	IFNA4 IFNA7 IFNA10 IFNA17	5.88e-05	29	168	4	CID000500901
Drug	SC-57099B	IFNA4 IFNA7 IFNA10	6.23e-05	11	168	3	CID000178079
Drug	penciclovir	IFNA4 IFNA7 IFNA10 IFNA17	6.75e-05	30	168	4	CID000004725
Drug	DZNep	IFNA4 IFNA7 IFNA10 IFNA17	6.75e-05	30	168	4	CID000073087
Drug	poly rI:rC	IFNA4 IFNA7 IFNA10 IFNA17	6.75e-05	30	168	4	CID011979660
Drug	2-nitroaniline	PACSIN1 APBB1 KAT2B QDPR DYNC1I1 HTT MYBL1	7.92e-05	139	168	7	CID000006946
Drug	casopitant	IFNA4 IFNA7 IFNA10	8.27e-05	12	168	3	CID009917021
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A	CADM3 PDE1C ARHGEF28 GLB1L ANKRD26 LDB3 FADS2 GAB1	1.00e-04	194	168	8	2893_UP
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; HL60; HT_HG-U133A	NES PDE4A SZT2 ZC3H13 ABCC9 ZC3H3 ZFPL1 PDGFD	1.04e-04	195	168	8	2924_UP
Drug	Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A	FAT4 UBE3B KIAA0319L CHD3 PLXND1 CUL7 KLHL18 HTT	1.04e-04	195	168	8	7377_UP
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A	EPHB6 UBE3B ANKRD26 CUL7 RGS14 PDE12 PLCB2 MYBL1	1.07e-04	196	168	8	2441_DN
Drug	Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A	CDKN1C SZT2 APBB1 PLXND1 CUL7 ZFPL1 RGS14 SMO	1.07e-04	196	168	8	4283_UP
Drug	AC1L1HZP	IFNA4 IFNA7 IFNA10 IFNA17 POSTN	1.11e-04	64	168	5	CID000004361
Drug	adefovir	IFNA4 IFNA7 IFNA10 IFNA17 ABCC10	1.11e-04	64	168	5	CID000060172
Drug	5H-purin-2-amine	IFNA4 IFNA7 IFNA10 IFNA17 PRRC2A HTT	1.11e-04	102	168	6	CID000409844
Drug	S-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; HL60; HT_HG-U133A	COL7A1 ZC3H13 PEX1 CHRNA5 ZFPL1 ERCC8 RGS14 KLHL18	1.11e-04	197	168	8	3094_UP
Drug	Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; HL60; HT_HG-U133A	CADM3 COL7A1 PDE1C ANK1 GLB1L ZFPL1 GAB1 EPHB1	1.11e-04	197	168	8	2151_UP
Drug	Trimeprazine tartrate [4330-99-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A	PDE4A KIAA0319L CHD3 ZFPL1 CEP152 ZNF839 ENPEP PRRC2A	1.11e-04	197	168	8	3478_DN
Drug	carprofen	IFNA4 IFNA7 IFNA10 IFNA17	1.12e-04	34	168	4	CID000002581
Drug	oxymatrine	IFNA4 IFNA7 IFNA10 IFNA17	1.12e-04	34	168	4	CID000114850
Drug	tenofovir disoproxil fumarate	IFNA4 IFNA7 IFNA10 IFNA17	1.12e-04	34	168	4	CID005481350
Drug	emtricitabine	PDE1C PDE4A IFNA4 IFNA7 IFNA10 IFNA17 AGT	1.13e-04	147	168	7	CID000060877
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	NES TAF1B UBE3B DHX38 ATG2B ZFPL1 ALMS1 C11orf68	1.15e-04	198	168	8	7010_DN
Drug	Methantheline bromide [53-46-3]; Down 200; 9.6uM; HL60; HT_HG-U133A	EPHB6 CDKN1C COL7A1 MREG ERCC8 PDE12 PDGFD KLHL18	1.15e-04	198	168	8	6137_DN
Drug	Methimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A	IL12RB2 GLB1L ANKRD26 PEX1 CUL7 ZFPL1 SMO GAB1	1.15e-04	198	168	8	4550_UP
Drug	retinoic acid; Up 200; 1uM; PC3; HT_HG-U133A	ANK1 DOCK10 ABCC9 ZFPL1 POSTN ALMS1 AGT KLHL18	1.19e-04	199	168	8	4435_UP
Drug	tilorone	IFNA4 IFNA7 IFNA10 IFNA17	1.25e-04	35	168	4	CID000005475
Drug	lobucavir	IFNA4 IFNA7 IFNA10 IFNA17	1.25e-04	35	168	4	CID000060786
Drug	AC1O51IP	IFNA4 IFNA7 IFNA10 IFNA17 PDGFD	1.28e-04	66	168	5	CID006450363
Drug	copolymer 1	IL12RB2 IFNA4 IFNA7 IFNA10 IFNA17	1.28e-04	66	168	5	CID003081884
Drug	MCNU	IFNA4 IFNA7 IFNA10 IFNA17	1.40e-04	36	168	4	CID000071741
Drug	A809128	IFNA4 IFNA7 IFNA10 IFNA17	1.40e-04	36	168	4	CID003392279
Drug	pyran	IFNA4 IFNA7 IFNA10 IFNA17	1.56e-04	37	168	4	CID000033703
Drug	FMAU	IFNA4 IFNA7 IFNA10 IFNA17	1.56e-04	37	168	4	CID000072327
Drug	2-[amino-[(2R,3R)-4-(dibenzylamino)-3-hydroxy-4-oxo-2-sulfanylbutanoyl]amino]acetic acid	IL12RB2 IFNA4 IFNA7 IFNA10	1.56e-04	37	168	4	CID016040231
Drug	cycloleucine	IFNA4 IFNA7 IFNA10 IFNA17 RGS8	1.58e-04	69	168	5	CID000002901
Drug	21-dehydrocortisol	SERPINA6 AGT	1.62e-04	3	168	2	CID000225755
Drug	AC1LCVPZ	PEX1 IFNA4 IFNLR1 IFNA7 IFNA10 IFNA17	1.68e-04	110	168	6	CID000656926
Drug	anagrelide	IFNA4 IFNA7 IFNA10 IFNA17	1.74e-04	38	168	4	CID000002182
Drug	fotemustine	IFNA4 IFNA7 IFNA10 IFNA17	1.74e-04	38	168	4	CID000104799
Drug	dipyridamole	PDE1C PDE1B IFNA4 IFNA7 IFNA10 IFNA17 SLC28A1	2.05e-04	162	168	7	CID000003108
Drug	AC1L1GHH	IFNA4 IFNA7 IFNA10 IFNA17 ABCC10	2.20e-04	74	168	5	CID000003685
Drug	p-nitrophenyl-alpha-D-glucopyranoside	FLT4 MANBA GLB1L TNS2 LCT POSTN	2.24e-04	116	168	6	CID000065115
Drug	dideoxyinosine	IFNA4 IFNA7 IFNA10 IFNA17 SLC28A1	2.34e-04	75	168	5	CID000003043
Drug	2',3'-dideoxycytidine (ddC	IFNA4 IFNA7 IFNA10 IFNA17 SLC28A1	2.49e-04	76	168	5	CID000005718
Drug	1 ind	IFNA4 IFNA7 IFNA10 IFNA17	2.57e-04	42	168	4	CID003037877
Drug	TORCH	IFNA4 IFNA7 IFNA10 IFNA17 HELB	2.65e-04	77	168	5	CID000015531
Drug	AC1MMF4B	F11 IFNA4 IFNA7 IFNA10 IFNA17	2.65e-04	77	168	5	CID003260010
Drug	AC1NRBRB	IFNA4 IFNA7 IFNA10 IFNA17	2.82e-04	43	168	4	CID005288597
Drug	NSC 312887	IFNA4 IFNA7 IFNA10 IFNA17	2.82e-04	43	168	4	CID000003368
Drug	Sesquimustard	IFNA4 IFNA7 IFNA10 IFNA17	2.82e-04	43	168	4	CID000019092
Drug	AC1L1J7E	COL7A1 SERPINA6 IFNA4 IFNA7 IFNA10 IFNA17 BANK1	2.86e-04	171	168	7	CID000004900
Disease	hyperinsulinism (is_implicated_in)	CDKN1C PTPRF AGT	3.38e-05	12	161	3	DOID:2018 (is_implicated_in)
Disease	bilirubin measurement	FAT4 ANK1 HJURP ABCC9 CHD3 GCKR FADS2 ATG4C KLHL8 EPHB1	1.67e-04	442	161	10	EFO_0004570
Disease	inflammatory bowel disease	IL12RB2 ZC3H13 UBR4 TOM1 GCKR UBASH3A RGS14 FADS2 PRRC2A BANK1	1.90e-04	449	161	10	EFO_0003767
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	GCKR FADS2 ATG4C	2.61e-04	23	161	3	OBA_2045158
Disease	1-myristoyl-2-linoleoyl-GPC (14:0/18:2) measurement	GCKR FADS2	2.93e-04	5	161	2	EFO_0800452
Disease	alpha-linolenic acid measurement	LCT FADS2 NLRP5	3.36e-04	25	161	3	EFO_0007759
Disease	3-hydroxybutyrate measurement	DHX38 APOC3 SERPINA6	3.36e-04	25	161	3	EFO_0010982
Disease	diacylglycerol 34:2 measurement	GCKR APOC3 FADS2	3.36e-04	25	161	3	EFO_0010353
Disease	urate measurement	COL7A1 DHX38 DDR2 LMTK2 CHD3 GCKR VARS2 CHRNA5 RGS14 PTPRF C11orf68 SLC28A1 FADS2 BANK1	4.14e-04	895	161	14	EFO_0004531
Disease	docosapentaenoic acid measurement	STIM2 GCKR FADS2	4.24e-04	27	161	3	EFO_0006809
Disease	gondoic acid measurement	GCKR FADS2	4.37e-04	6	161	2	EFO_0007975
Disease	triacylglycerol 54:7 measurement	CNTN4 GCKR FADS2	4.72e-04	28	161	3	EFO_0010425
Disease	cholesteryl ester 24:4 measurement	TNS2 FADS2	6.10e-04	7	161	2	EFO_0021447
Disease	Antihypertensive use measurement	STIM2 UBE3B DDR2 KAT2B AGT ENPEP ABCC10	6.56e-04	265	161	7	EFO_0009927
Disease	Large cell carcinoma of lung	DDR2 LMTK2 BMX	7.04e-04	32	161	3	C0345958
Disease	apolipoprotein A 1 measurement	COL7A1 ARHGEF28 DHX38 AKNA GCKR APOC3 ZRANB3 LDB3 PDGFD FADS2 ATG4C BANK1 CCDC102A	8.02e-04	848	161	13	EFO_0004614
Disease	1-stearoyl-2-docosapentaenoyl-GPC (18:0/22:5n3) measurement	GCKR FADS2	8.11e-04	8	161	2	EFO_0800455
Disease	Malignant neoplasm of breast	COL7A1 WARS1 ANK1 PPP1R12B UBR4 LRRC37A2 LRRC37A OTOF SIPA1L1 SLC28A1 LRRC7 ENPEP PRRC2A TOP2A GAB1	8.30e-04	1074	161	15	C0006142
Disease	phosphatidylcholine 32:1 measurement	HJURP GCKR FADS2	1.17e-03	38	161	3	EFO_0010373
Disease	obesity (implicated_via_orthology)	FAT4 STIM2 ANKRD26 PLXND1 ALMS1 PLCB2	1.20e-03	215	161	6	DOID:9970 (implicated_via_orthology)
Disease	1-palmitoyl-2-oleoyl-GPE (16:0/18:1) measurement	GCKR FADS2	1.29e-03	10	161	2	EFO_0800608
Disease	oleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement	GCKR FADS2	1.29e-03	10	161	2	EFO_0800507
Disease	1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) measurement	GCKR FADS2	1.29e-03	10	161	2	EFO_0800464
Disease	level of Sterol ester (27:1/18:3) in blood serum	GCKR FADS2	1.29e-03	10	161	2	OBA_2045193
Disease	level of phosphatidylcholine	GCKR FADS2	1.29e-03	10	161	2	OBA_2040179
Disease	1-stearoyl-2-oleoyl-GPE (18:0/18:1) measurement	GCKR FADS2	1.58e-03	11	161	2	EFO_0800269
Disease	mean arterial pressure	STIM2 WARS1 SZT2 DOCK10 TNS2 AGT SLC28A1 ENPEP ABCC10	1.75e-03	499	161	9	EFO_0006340
Disease	platelet measurement	GLB1L DOCK10 GCKR ERCC8 PTPRF FADS2 BANK1	1.78e-03	315	161	7	EFO_0005036
Disease	phosphatidylcholine 34:4 measurement	GCKR FADS2	1.88e-03	12	161	2	EFO_0010378
Disease	triacylglycerol 53:2 measurement	GCKR FADS2	1.88e-03	12	161	2	EFO_0021484
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	GCKR FADS2	1.88e-03	12	161	2	EFO_0800453
Disease	cholesteryl ester 24:5 measurement	TNS2 FADS2	1.88e-03	12	161	2	EFO_0021448
Disease	level of Phosphatidylcholine (16:0_20:2) in blood serum	GCKR FADS2	1.88e-03	12	161	2	OBA_2045074
Disease	QRS complex, QRS duration	DDR2 SIPA1L1 FADS2	1.91e-03	45	161	3	EFO_0005054, EFO_0005055
Disease	smoking cessation	TOM1L2 PDE1C TOM1 ANKS1B CHRNA5 ALMS1 PTPRF	2.12e-03	325	161	7	EFO_0004319
Disease	autism spectrum disorder, schizophrenia	CNTN4 CHRNA5 PTPRF SIPA1L1 PRRC2A BANK1 ABCC10	2.19e-03	327	161	7	EFO_0003756, MONDO_0005090
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	GCKR FADS2	2.22e-03	13	161	2	OBA_2045072
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	GCKR FADS2	2.22e-03	13	161	2	OBA_2045082
Disease	sleep duration, triglyceride measurement	GCKR APOC3 FADS2 KLHL8	2.57e-03	104	161	4	EFO_0004530, EFO_0005271
Disease	1-methylurate measurement	CNTN4 PTPRF	2.58e-03	14	161	2	EFO_0021173
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	FADS2 ATG4C	2.58e-03	14	161	2	OBA_2045100
Disease	level of Phosphatidylethanolamine (18:2_0:0) in blood serum	GCKR FADS2	2.58e-03	14	161	2	OBA_2045143
Disease	polyunsaturated fatty acids to total fatty acids percentage	GCKR FADS2 KLHL8	2.59e-03	50	161	3	EFO_0022303
Disease	phosphatidylethanolamine measurement	ABCC9 GCKR APOC3 ERCC8 FADS2	2.65e-03	173	161	5	EFO_0010228
Disease	Nephrosis	NES AGT	2.97e-03	15	161	2	C0027720
Disease	amyotrophic lateral sclerosis, age at onset	ANKS1B PTPRF	2.97e-03	15	161	2	EFO_0004847, MONDO_0004976
Disease	tumor necrosis factor measurement	APBB1 NFKBIL1	2.97e-03	15	161	2	EFO_0010834
Disease	level of Triacylglycerol (53:3) in blood serum	GCKR FADS2	2.97e-03	15	161	2	OBA_2045165
Disease	lung small cell carcinoma (is_marker_for)	APOC3 CHRNA5	3.38e-03	16	161	2	DOID:5409 (is_marker_for)
Disease	vitamin C measurement	RGS14 FADS2	3.38e-03	16	161	2	EFO_0600003
Disease	phosphatidylcholine 32:2 measurement	GCKR FADS2	3.38e-03	16	161	2	EFO_0010374
Disease	diacylglycerol 36:2 measurement	APOC3 FADS2	3.38e-03	16	161	2	EFO_0010355
Disease	level of Sterol ester (27:1/18:0) in blood serum	EIF4B FADS2	3.38e-03	16	161	2	OBA_2045196
Disease	diacylglycerol 44:7 measurement	GCKR APOC3	3.38e-03	16	161	2	EFO_0020069
Disease	response to acetylsalicylate	KLHL18 EPHB1	3.38e-03	16	161	2	GO_1903492
Disease	sex interaction measurement, inflammatory bowel disease	GCKR UBASH3A PRRC2A	3.40e-03	55	161	3	EFO_0003767, EFO_0008343
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	GCKR F11 FNIP1	3.58e-03	56	161	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	apolipoprotein B measurement	ANK1 DHX38 GCKR APOC3 SERPINA6 PDGFD FADS2 ATG4C RP1 HTT	3.59e-03	663	161	10	EFO_0004615
Disease	erythritol measurement	DDR2 BANK1	3.81e-03	17	161	2	EFO_0021171
Disease	level of Phosphatidylcholine (14:0_18:2) in blood serum	GCKR FADS2	3.81e-03	17	161	2	OBA_2045063
Disease	response to carboplatin	STIM2 IFNLR1 QDPR	3.95e-03	58	161	3	GO_0097328
Disease	serum urea measurement	GCKR RGS14 C11orf68 ABCC10 EPHB1	4.42e-03	195	161	5	EFO_0009795
Disease	chronic obstructive pulmonary disease	ARHGEF28 PPP1R12B LRRC37A2 DOCK10 VARS2 CHRNA5 NFKBIL1 RASGEF1C SSH2 SPPL2C	4.65e-03	688	161	10	EFO_0000341
Disease	level of Phosphatidylethanolamine (18:0_20:4) in blood serum	APOC3 FADS2	4.76e-03	19	161	2	OBA_2045140
Disease	ovulation	GCM2 PRRC2A	4.76e-03	19	161	2	GO_0030728
Disease	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa	CNTN4 ANKS1B PTPRF FADS2 BANK1	4.91e-03	200	161	5	EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Disease	triglycerides to total lipids in IDL percentage	GCKR FADS2 BANK1	4.98e-03	63	161	3	EFO_0022329
Disease	chronic kidney disease (is_marker_for)	APOC3 POSTN	5.27e-03	20	161	2	DOID:784 (is_marker_for)
Disease	level of Phosphatidylcholine (16:0_18:2) in blood serum	FADS2 ATG4C	5.27e-03	20	161	2	OBA_2045071
Disease	esterified cholesterol measurement	DHX38 GCKR APOC3 FADS2	5.39e-03	128	161	4	EFO_0008589

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEADREPWETQDSFS	USHBP1	246	Q8N6Y0
AVWSQRPFSDLEDLE	URAD	31	A6NGE7
SQSRWEISTEQEPED	BANK1	131	Q8NDB2
PRQAEDLGWSSSEFE	ARHGEF10L	161	Q9HCE6
QLWPESSTSDVVRDD	CEP152	606	O94986
SWEFPESSSSEEEEN	BMX	276	P51813
TWTEQPEAESSQADR	ANK1	1761	P16157
VSAFDSDSIPSWSRF	FAT4	3426	Q6V0I7
WSSRPSEVSEALFQA	ALMS1	266	Q8TCU4
RSLSATDIEVFWASP	CNTN4	811	Q8IWV2
DDSWRTGESSLPFES	ABCC9	616	O60706
WSNVNESEPSFEATR	ABCC9	731	O60706
DSFWNPNAFETDSDL	APBB1	241	O00213
ESSRQVTSESQEEPW	FAM186B	466	Q8IYM0
DSWPTSDDEDLNFDT	ANKRD26	256	Q9UPS8
LSQDDSQPWTSDETV	CADM3	26	Q8N126
EADFSSWTPLEFLVE	QDPR	196	P09417
SEDEAWPSLFDTFVE	DCUN1D3	261	Q8IWE4
DTTSSDDFDWPRIVL	ATG2B	836	Q96BY7
PDALNIENSDSESWT	ATG4C	136	Q96DT6
AEPQEFWVDNSTSVS	AGT	286	P01019
WINEPLSDSESEDER	AP3D1	626	O14617
ATSDQEESVAWALAP	HJURP	121	Q8NCD3
TSDFDFELEPDDWTT	INSYN1	61	Q2T9L4
AFTPDWESREVSTGT	PSMB6	21	P28072
PEEVWATSADRYTDV	KIAA1549	311	Q9HCM3
FQTERRESWSSAPEL	RADIL	591	Q96JH8
VDSSLWSDLSSDAQE	ARHGEF28	811	Q8N1W1
ERTPSFTSEWEEIDK	ANKS1B	771	Q7Z6G8
AAEREVSVPTFSWEE	FADS2	11	O95864
SIPDFTAFTTVDDWL	EPHB1	906	P54762
PEVAEDGESWLSRFS	ABCC10	211	Q5T3U5
FSTEDSSAAWEQSLL	IFNA10	91	P01566
ESTENLVPFLDTWDS	LRRC37A3	101	O60309
SPEEITSLWSELFNS	MDN1	3001	Q9NU22
ERSLTAGLEFWSEDT	MAGEE2	296	Q8TD90
SESRSPLEDETDNTW	KIAA1671	1671	Q9BY89
ESTENLVPFLDTWDS	LRRC37A2	101	A6NM11
ESTENLVPFLDTWDS	LRRC37A	101	A6NMS7
PEDEADEWARRSSNL	LDB3	256	O75112
FLEELPEDNLSSWAT	IFNLR1	436	Q8IU57
NSPIWDQDFLSASSR	KAT2B	361	Q92831
DFQSDSDSFNPTLWE	LRRC7	436	Q96NW7
FRSEASEWEPNAISF	DDR2	306	Q16832
ELDSDDAIFTWPDRE	KIAA0319L	1006	Q8IZA0
AWTDGRQSTESETPA	GAB1	676	Q13480
NFFTDLIQDWSSDSP	KIAA1109	496	Q2LD37
SDWSESLRAQTPEEE	IL12RB2	306	Q99665
WDTDPSVLQLQSDSE	DYNC1I1	126	O14576
RNPVFQDSWDTESSG	FAM104A	96	Q969W3
EDFQPAAASETNWES	PDGFD	171	Q9GZP0
PRAEDVDLEWFASST	PLXND1	1601	Q9Y4D7
ERYDIESDQWSTVAP	KLHL8	431	Q9P2G9
PSSSWTETDVEERVY	PDE12	221	Q6L8Q7
DAVPSEVRDWLASTF	PDE1B	91	Q01064
SDIQSDAVPSEVRDW	PDE1C	91	Q14123
DAVPSEVRDWLASTF	PDE1C	96	Q14123
LDATIAWEASPAQES	PDE4A	746	P27815
NNFLTSSWRDDDFVP	CUL7	1156	Q14999
FSTEDSSAAWEQSLL	IFNA7	91	P01567
EFLESDSVSVSVPWD	NES	1456	P48681
DWESDRNFISTAGPL	LCT	21	P09848
DEASSPWSVLNAELS	LMTK2	1196	Q8IWU2
FNDSSPVVLEESWDA	GCN1	2201	Q92616
SVTEFISREWPDSQA	NLRP5	331	P59047
DPSRDAAESSEWTLA	MROH6	541	A6NGR9
TSDFWAALEEASRLP	ENPEP	516	Q07075
ETQEPESFSAWSDRL	NFKBIL1	191	Q9UBC1
LNPAFEDAWSSSDEE	ERCC8	381	Q13216
SDAWEASDQSLIASP	FAM131B	201	Q86XD5
ENASDTDRSEGLSPW	LRRC66	791	Q68CR7
DEASLAPEETTDSFW	PACSIN1	6	Q9BY11
NDPIEDWSSTFRQVA	GCKR	216	Q14397
DSVWTPDIVLFDNAD	CHRNA5	126	P30532
SDWSLAPTEEERESF	FMR1	511	Q06787
RSSWASEEEANPAAT	HTT	1106	P42858
STVEAYNPETDTWTR	KLHL18	351	O94889
PSDDFSAATVSWDIR	DOCK10	76	Q96BY6
QPSSSSEDSDEEWRR	CUSTOS	146	Q96C57
RLQWTEVDSDSVPAF	CDKN1C	76	P49918
ATADTVIIFDSDWNP	CHD3	1146	Q12873
SPILDQEDSWRDSAS	FRMPD2B	211	Q6IN97
VFPRWSIEESFNLSD	FNIP1	301	Q8TF40
RLPWEDTAATEEEAS	CCDC102A	236	Q96A19
AFSPSTWELTEEEEA	FOXR1	121	Q6PIV2
RTSDPDFLAAVDSWF	GLB1L	146	Q6UWU2
FTAESPSEDPTRWFT	F11	61	P03951
SSSQSWEEERLFPNA	AKNA	36	Q7Z591
WLPENRDISEDQSSA	AKNA	546	Q7Z591
WSDSSQVSSPERDNE	CAPRIN2	941	Q6IMN6
NWIPADSFQDRVTSE	MANBA	356	O00462
DSWQALSEDPAAQER	MBLAC1	201	A4D2B0
DSSPDFEDTWRFLEN	COQ9	261	O75208
LREIVETWDESSGSF	COL7A1	1956	Q02388
FSREILWSGTSESED	CCDC168	131	Q8NDH2
PIFQDSQDTEFSWSD	FAM104B	31	Q5XKR9
TRPSISEDDWKNFAE	PEX1	1241	O43933
TWTQPFDLASTREEN	SERPINA6	206	P08185
TPFSVRRSWDSLNED	C4orf19	231	Q8IY42
NDVTWSEASSPDERT	HELB	996	Q8NG08
FSTEDSSAAWEQSLL	IFNA17	91	P01571
ESDPVAWSDVTSFDI	MYBL1	366	P10243
VADFDETFRWPVASS	OTOF	41	Q9HC10
QWRPEESEDYETTIS	PTPRF	771	P10586
ATQGPLAESTEDFWR	PTPRF	1711	P10586
DTDWRARPATDSFDD	EIF4B	196	P23588
PVTSDWSDYRPDSDS	RP1	1586	P56715
EEDFVDPWTVQTSSA	WARS1	81	P23381
LERDPDVLDTWFSSA	VARS2	576	Q5ST30
VAESEEDLWRSETPF	SZT2	1986	Q5T011
STEEATRWADSFDVL	RGS8	46	P57771
DPEWSSETDALVGSR	TMEM179B	201	Q7Z7N9
ENSTSATWEEREESP	TDRD6	296	O60522
PFRAKSEESEATSWF	SYNJ1	1416	O43426
SADSSENWPSEEEIR	LRRC27	246	Q9C0I9
QSFLVSDPENTTWAD	NBR1	16	Q14596
LEESASRAPSTWEES	MRM3	76	Q9HC36
SPSSFQFNWTEEDTD	TAF1B	471	Q53T94
PVQSLRSLDSDDFWT	TDRD10	291	Q5VZ19
EETNIFPTSWELSER	MREG	151	Q8N565
LSPQEWEADRETGSS	GAS8-AS1	86	O95177
RWTKVDTIAADESFP	EPHB6	151	O15197
EPVSSRTDEAETWDV	GCM2	466	O75603
SREVTEDAADWAPAL	PRKY	16	O43930
SRDWELLPSAAASAE	PRRC2A	1796	P48634
ATNPEDRSDSSEGWS	SPPL2C	591	Q8IUH8
SDLEDNRSEDSVRPW	SIPA1L1	311	O43166
PDTAADLDWSNLVDA	SIPA1L1	1671	O43166
SVSLEDWLDFSSTNV	TEKT1	211	Q969V4
SFESLPNTETDREPW	STARD9	2646	Q9P2P6
FSTEDSSAAWEQSLL	IFNA4	91	P05014
TARWVTNNDSFAPED	SNAPC3	361	Q92966
SARFPSWVTFDDNEV	STON2	226	Q8WXE9
SEFWLSLDESPAAAQ	B4GALNT4	191	Q76KP1
ESFETSAPWDRVVDL	AGPS	526	O00116
FSEFWDLDPEVRPTS	APOC3	81	P02656
FDARTTPATELDAWL	C11orf68	81	Q9H3H3
DDPTSKREQWFRFST	TSGA13	166	Q96PP4
AQRGSLEEFEETPWS	ZC3H3	141	Q8IXZ2
SSFTRDLWPEQDIKD	ZNF714	51	Q96N38
ESDQPLNEFWSSDSQ	RNASE10	36	Q5GAN6
SPEETSRWLRSEVEN	TMEM143	386	Q96AN5
EQVSWEESQESPLSS	SSH2	1156	Q76I76
EAPAFTIDNRSSWEN	SPO11	66	Q9Y5K1
EKEFELRSSWSVPDA	STIM2	336	Q9P246
IQSWADAFRSSPDLT	TOM1	121	O60784
EWTETFPRDFQEEST	RASGEF1C	116	Q8N431
DDPRDVSSQWASSVN	ZSCAN5B	156	A6NJL1
ESTDSSIPWFLRVQE	ZNF410	156	Q86VK4
DAVNPIESLDTWTEF	FLT4	496	P35916
SLPFTFDVERSIDDW	XRN2	321	Q9H0D6
DAATPSRSTWEEEDS	DHX38	206	Q92620
TEEQPVASWALSFER	RGS14	56	O43566
SSDAVAITWADRAFP	SLC7A13	271	Q8TCU3
QEDESSPWFESETQI	SUCO	601	Q9UBS9
DLNEPSADVSSAWAQ	SMO	606	Q99835
ERFIKWDDETTVASP	PLCB2	21	Q00722
DLSPAEIRSSWSEAA	SLC28A1	41	O00337
SSDQDTWDSLRSPGF	ZNF839	616	A8K0R7
RNPWSDSESDRSSDE	TOP2A	1291	P11388
SASPRSWDEAEAQEE	WRNIP1	151	Q96S55
LWDILASDFTPDERA	UBE3B	956	Q7Z3V4
SAELSSPWAARDSEQ	VWA5B2	616	Q8N398
SPWAARDSEQSTDAL	VWA5B2	621	Q8N398
LDREWEEEPLSTATF	WDR93	341	Q6P2C0
PTSRETSESWTNQDD	nan	21	Q6ZS52
SVDWETVDFDSAPSI	SUOX	406	P51687
APSNEAWDNLDSDIR	POSTN	136	Q15063
IQAWADAFRSSPDLT	TOM1L2	121	Q6ZVM7
SWRNAFANDTIPSES	UBR4	1246	Q5T4S7
FDLSWEATSSQFRPE	TTYH3	21	Q9C0H2
NTDDFTTETLEWRLG	TXNDC9	166	O14530
FAFTRDDSVPEDNIW	PTDSS1	56	P48651
SVDYNTTEPAVRWDS	TNS2	441	Q63HR2
DNESWPSTAEADRDR	WWC3	256	Q9ULE0
EPLNTSDFSDWSSFN	ZFPL1	146	O95159
DTAFSDWSDEDVPDR	ZC3H13	1061	Q5T200
SRFLQSISWDPEDFE	TLE6	241	Q9H808
LPENYTDRASESDTW	UBASH3A	331	P57075
QFAEAWTPNDSSEEL	ZRANB3	491	Q5FWF4
WTNRFSVPDSESSET	PPP1R12B	751	O60237