Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2A	2.30e-04	8	58	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2A	3.68e-04	10	58	2	GO:0140999
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2A MECP2	3.68e-04	10	58	2	GO:0045322
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	DDX17 MRPL44 DDX42 DDX51 TFB2M NOP2	1.29e-03	417	58	6	GO:0140098
GeneOntologyMolecularFunction	chromatin DNA binding	H1-8 DDX17 KDM3B MECP2	1.41e-03	167	58	4	GO:0031490
GeneOntologyMolecularFunction	transcription factor binding	NOLC1 FLNA BAZ2A KMT2A TACC1 TAF4 SIX3 MECP2	1.42e-03	753	58	8	GO:0008134
GeneOntologyMolecularFunction	RNA helicase activity	DDX17 DDX42 DDX51	1.52e-03	78	58	3	GO:0003724
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2C KMT2A	1.52e-03	20	58	2	GO:0042800
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	KMT2C KMT2A TFB2M NOP2	1.57e-03	172	58	4	GO:0008757
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX17 DDX42 DDX51	1.63e-03	80	58	3	GO:0008186
GeneOntologyMolecularFunction	immunoglobulin receptor binding	FLNA CR2	1.68e-03	21	58	2	GO:0034987
GeneOntologyMolecularFunction	rRNA methyltransferase activity	TFB2M NOP2	2.20e-03	24	58	2	GO:0008649
GeneOntologyMolecularFunction	catalytic activity, acting on a rRNA	TFB2M NOP2	2.38e-03	25	58	2	GO:0140102
GeneOntologyBiologicalProcess	telencephalon development	FLNA FOXB1 POMGNT1 TACC1 SIX3 MECP2 AGTPBP1	2.75e-05	332	55	7	GO:0021537
GeneOntologyBiologicalProcess	rRNA processing	NOLC1 DDX17 MRPL44 DDX51 TFB2M NOP2	3.31e-05	230	55	6	GO:0006364
GeneOntologyBiologicalProcess	rRNA metabolic process	NOLC1 DDX17 MRPL44 DDX51 TFB2M NOP2	8.91e-05	275	55	6	GO:0016072
Domain	AT_hook	KMT2C BAZ2A KMT2A MECP2 SCML4	1.55e-08	27	56	5	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2C BAZ2A KMT2A MECP2 SCML4	1.55e-08	27	56	5	IPR017956
Domain	AT_hook	KMT2C BAZ2A KMT2A MECP2	1.28e-07	16	56	4	PF02178
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	5.28e-05	4	56	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	5.28e-05	4	56	2	PF01557
Domain	-	FAHD2B FAHD2A	5.28e-05	4	56	2	3.90.850.10
Domain	FYrich_C	KMT2C KMT2A	8.78e-05	5	56	2	IPR003889
Domain	FYrich_N	KMT2C KMT2A	8.78e-05	5	56	2	IPR003888
Domain	FYRC	KMT2C KMT2A	8.78e-05	5	56	2	SM00542
Domain	FYRN	KMT2C KMT2A	8.78e-05	5	56	2	SM00541
Domain	FYRN	KMT2C KMT2A	8.78e-05	5	56	2	PF05964
Domain	FYRC	KMT2C KMT2A	8.78e-05	5	56	2	PF05965
Domain	FYRC	KMT2C KMT2A	8.78e-05	5	56	2	PS51543
Domain	FYRN	KMT2C KMT2A	8.78e-05	5	56	2	PS51542
Domain	HMGI/Y_DNA-bd_CS	KMT2C BAZ2A MECP2	1.08e-04	31	56	3	IPR000637
Domain	DEAD_ATP_HELICASE	DDX17 DDX42 DDX51	1.08e-04	31	56	3	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX17 DDX42 DDX51	1.31e-04	33	56	3	IPR000629
Domain	SIX1_SD	SIX3 SIX6	1.84e-04	7	56	2	PF16878
Domain	SIX1_SD	SIX3 SIX6	1.84e-04	7	56	2	IPR031701
Domain	-	BAZ2A MECP2	2.44e-04	8	56	2	3.30.890.10
Domain	TF_fork_head_CS_2	FOXB1 FOXB2 FOXL1	3.54e-04	46	56	3	IPR030456
Domain	TF_fork_head_CS_1	FOXB1 FOXB2 FOXL1	3.77e-04	47	56	3	IPR018122
Domain	IG_FLMN	FLNA FLNC	3.91e-04	10	56	2	SM00557
Domain	FH	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	SM00339
Domain	FORK_HEAD_1	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	PS00657
Domain	FORK_HEAD_2	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	PS00658
Domain	Fork_head_dom	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	IPR001766
Domain	FORK_HEAD_3	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	PS50039
Domain	Forkhead	FOXB1 FOXB2 FOXL1	4.27e-04	49	56	3	PF00250
Domain	Filamin	FLNA FLNC	4.77e-04	11	56	2	PF00630
Domain	Methyl_CpG_DNA-bd	BAZ2A MECP2	4.77e-04	11	56	2	IPR001739
Domain	MBD	BAZ2A MECP2	4.77e-04	11	56	2	PF01429
Domain	FILAMIN_REPEAT	FLNA FLNC	4.77e-04	11	56	2	PS50194
Domain	DNA-bd_dom	BAZ2A MECP2	4.77e-04	11	56	2	IPR016177
Domain	Filamin/ABP280_rpt	FLNA FLNC	4.77e-04	11	56	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC	4.77e-04	11	56	2	IPR017868
Domain	MBD	BAZ2A MECP2	4.77e-04	11	56	2	SM00391
Domain	MBD	BAZ2A MECP2	4.77e-04	11	56	2	PS50982
Domain	Znf_FYVE_PHD	KMT2C BAZ2A KMT2A MLPH	9.85e-04	147	56	4	IPR011011
Domain	Post-SET_dom	KMT2C KMT2A	1.03e-03	16	56	2	IPR003616
Domain	PostSET	KMT2C KMT2A	1.03e-03	16	56	2	SM00508
Domain	POST_SET	KMT2C KMT2A	1.03e-03	16	56	2	PS50868
Domain	-	FLNA FLNC CEP95	1.26e-03	71	56	3	1.10.418.10
Domain	DEAD/DEAH_box_helicase_dom	DDX17 DDX42 DDX51	1.37e-03	73	56	3	IPR011545
Domain	DEAD	DDX17 DDX42 DDX51	1.37e-03	73	56	3	PF00270
Domain	PHD	KMT2C BAZ2A KMT2A	1.48e-03	75	56	3	PF00628
Domain	CH-domain	FLNA FLNC CEP95	1.48e-03	75	56	3	IPR001715
Domain	Znf_PHD-finger	KMT2C BAZ2A KMT2A	1.72e-03	79	56	3	IPR019787
Domain	DS_RBD	ILF3 MRPL44	1.79e-03	21	56	2	PS50137
Domain	EPHD	KMT2C KMT2A	1.96e-03	22	56	2	PS51805
Domain	Actinin_actin-bd_CS	FLNA FLNC	2.15e-03	23	56	2	IPR001589
Domain	ACTININ_2	FLNA FLNC	2.15e-03	23	56	2	PS00020
Domain	ACTININ_1	FLNA FLNC	2.15e-03	23	56	2	PS00019
Domain	PHD	KMT2C BAZ2A KMT2A	2.42e-03	89	56	3	SM00249
Domain	DHHC	KMT2C ZDHHC5	2.53e-03	25	56	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	KMT2C ZDHHC5	2.53e-03	25	56	2	IPR001594
Domain	Znf_PHD	KMT2C BAZ2A KMT2A	2.57e-03	91	56	3	IPR001965
Domain	ZF_PHD_2	KMT2C BAZ2A KMT2A	2.91e-03	95	56	3	PS50016
Domain	-	ILF3 MRPL44	2.95e-03	27	56	2	3.30.160.20
Domain	ZF_PHD_1	KMT2C BAZ2A KMT2A	3.00e-03	96	56	3	PS01359
Domain	dsRBD_dom	ILF3 MRPL44	3.17e-03	28	56	2	IPR014720
Domain	Helicase_C	DDX17 DDX42 DDX51	4.07e-03	107	56	3	PF00271
Domain	HELICc	DDX17 DDX42 DDX51	4.07e-03	107	56	3	SM00490
Domain	-	FOXB1 H1-8 FOXB2 FOXL1	4.13e-03	218	56	4	1.10.10.10
Domain	Helicase_C	DDX17 DDX42 DDX51	4.17e-03	108	56	3	IPR001650
Domain	HELICASE_CTER	DDX17 DDX42 DDX51	4.28e-03	109	56	3	PS51194
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RALY NOLC1 FLNA ILF3 DDX17 TRNAU1AP MRPL44 DDX42 DDX51 CHCHD1 TFB2M NOP2 RPL15	6.19e-10	807	58	13	22681889
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RALY NOLC1 FLNA FLNC ILF3 DDX17 DDX42 KMT2A TAF4 MLPH ATP2B1 MECP2 CFAP46 BAHCC1 SCML4	9.49e-09	1442	58	15	35575683
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NOLC1 FLNA ILF3 BAZ2A PDPK1 KDM3B KMT2A DDX51 NOP2 MECP2 AGTPBP1	5.43e-08	774	58	11	15302935
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RALY NOLC1 FLNA FLNC ILF3 DDX17 DDX42 C19orf47 NOP2 F5 ATP2B1 RPL15	1.02e-07	1024	58	12	24711643
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	RALY NOLC1 FLNA FLNC ILF3 DDX17 TRNAU1AP NOP2 RPL15	1.26e-07	494	58	9	26831064
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RALY NOLC1 KMT2C ILF3 DDX17 BAZ2A DDX42 KMT2A DDX51 TAF4 NOP2 MECP2 RPL15	1.64e-07	1294	58	13	30804502
Pubmed	Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.	NOLC1 FLNA FLNC DDX17 RPL15 BAHCC1	2.76e-07	159	58	6	34537242
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NOLC1 FLNA ILF3 DDX17 BAZ2A DDX42 KDM3B KMT2A TACC1 NOP2 RPL15	3.55e-07	934	58	11	33916271
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	RALY ILF3 DDX17 BAZ2A DDX42 NOP2 MECP2	4.63e-07	283	58	7	30585729
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	NOLC1 ILF3 DDX17 DDX42 C19orf47 KMT2A DDX51 NOP2 RPL15	6.85e-07	605	58	9	28977666
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	NOLC1 FLNA ILF3 DDX17 TAF4 NOP2 MECP2 RPL15	6.91e-07	441	58	8	31239290
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALY NOLC1 ILF3 BAZ2A MRPL44 DDX42 ZDHHC5 TACC1 DNAJB5 NOP2 ATP2B1 AGTPBP1 RPL15	7.92e-07	1487	58	13	33957083
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NOLC1 FLNA FLNC BAZ2A DDX42 KMT2A DDX51 NOP2 RPL15	1.29e-06	653	58	9	22586326
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	RALY NOLC1 ILF3 DDX17 BAZ2A NOP2 MECP2	1.29e-06	330	58	7	33301849
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	RALY NOLC1 FLNA ILF3 DDX17 DDX42 ZDHHC5 NOP2 F5	1.41e-06	660	58	9	32780723
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RALY NOLC1 FLNA ILF3 DDX17 BAZ2A C19orf47 KDM3B KMT2A TAF4 NOP2 RPL15	1.48e-06	1318	58	12	30463901
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NOLC1 ILF3 BAZ2A DDX42 KDM3B KMT2A NOP2	1.60e-06	341	58	7	32971831
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXB1 FOXB2 FOXL1	1.97e-06	15	58	3	7689224
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	RALY ILF3 DDX17 MRPL44 NOP2 RPL15	1.99e-06	223	58	6	20020773
Pubmed	SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus.	SIX3 MECP2 SIX6	2.43e-06	16	58	3	35008655
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	2.73e-06	2	58	2	15774318
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	2.73e-06	2	58	2	7689010
Pubmed	Comparative analysis of Six 3 and Six 6 distribution in the developing and adult mouse brain.	SIX3 SIX6	2.73e-06	2	58	2	15973738
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	2.73e-06	2	58	2	10679933
Pubmed	Six3 and Six6 jointly control diverse target genes in multiple cell populations over developmental trajectories of mouse embryonic retinal progenitor cells.	SIX3 SIX6	2.73e-06	2	58	2	39446806
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	2.73e-06	2	58	2	24469451
Pubmed	Screening E3 substrates using a live phage display library.	NOLC1 DDX42 RPL15	2.94e-06	17	58	3	24124579
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	NOLC1 ILF3 DDX17 TRNAU1AP MRPL44 DDX42 NOP2 MECP2 RPL15	2.96e-06	723	58	9	34133714
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	FLNA FLNC ILF3 DDX17 MRPL44 TFB2M NOP2 ATP2B1 RPL15	3.03e-06	725	58	9	27025967
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RALY NOLC1 FLNA ILF3 DDX17 DDX51 TAF4 NOP2 SHC3 RPL15	3.48e-06	949	58	10	36574265
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	RALY FLNA FLNC ILF3 DDX17 DDX42 TAF4 NOP2	3.61e-06	551	58	8	34728620
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NOLC1 FLNA ILF3 DDX17 BAZ2A DDX42 KMT2A TAF4 NOP2 MECP2	3.64e-06	954	58	10	36373674
Pubmed	The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules.	RALY NOLC1 ILF3 NOP2	4.37e-06	65	58	4	32521226
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	RALY NOLC1 ILF3 DDX42 NOP2	4.98e-06	148	58	5	32538781
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	FLNA BAZ2A MECP2 RPL15	6.58e-06	72	58	4	31248990
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	RALY NOLC1 ILF3 DDX17 NOP2 MECP2 RPL15	7.34e-06	430	58	7	38172120
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNC	8.19e-06	3	58	2	11252955
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	8.19e-06	3	58	2	12704190
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	8.19e-06	3	58	2	11038172
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2A	8.19e-06	3	58	2	23932714
Pubmed	The clinical variability of the MECP2 duplication syndrome: description of two families with duplications excluding L1CAM and FLNA.	FLNA MECP2	8.19e-06	3	58	2	19018795
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	8.19e-06	3	58	2	38287013
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	8.19e-06	3	58	2	11102480
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	8.19e-06	3	58	2	17825253
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNC	8.19e-06	3	58	2	12393796
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	8.19e-06	3	58	2	9412467
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNC	8.19e-06	3	58	2	11153914
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	RALY FLNA ILF3 DDX17 NOP2 RPL15	9.89e-06	295	58	6	26209609
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RALY NOLC1 FLNC ILF3 DDX17 MRPL44 DDX42 MECP2 ARHGAP33 RPL15	1.10e-05	1082	58	10	38697112
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	NOLC1 FLNA ILF3 DDX17 NOP2 ATP2B1 RPL15	1.19e-05	463	58	7	34901782
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RALY NOLC1 FLNA FLNC ILF3 DDX17 BAZ2A DDX51 NOP2 ATP2B1 RPL15	1.26e-05	1353	58	11	29467282
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	NOLC1 FLNA ILF3 DDX17 TFB2M TAF4 NOP2 RPL15	1.27e-05	655	58	8	35819319
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NOLC1 FLNA KMT2C ILF3 DDX17 KDM3B KMT2A TAF4 NOP2 MECP2	1.29e-05	1103	58	10	34189442
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RALY FLNA ILF3 TRNAU1AP KMT2A CHCHD1 NOP2 MECP2 SHC3 AGTPBP1 RPL15	1.42e-05	1371	58	11	36244648
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	FLNA ILF3 DDX51 TAF4 NOP2 RPL15	1.46e-05	316	58	6	31665637
Pubmed	The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.	FLNA FLNC	1.64e-05	4	58	2	20554076
Pubmed	The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice.	SIX3 SIX6	1.64e-05	4	58	2	39025297
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNC	1.64e-05	4	58	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNC	1.64e-05	4	58	2	22802962
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2A	1.64e-05	4	58	2	23129768
Pubmed	Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.	KMT2C KMT2A	1.64e-05	4	58	2	19703992
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2A	1.64e-05	4	58	2	24081332
Pubmed	Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk.	SIX3 SIX6	1.64e-05	4	58	2	10473118
Pubmed	Phosphoinositide-dependent kinase 1 regulates leukemia stem cell maintenance in MLL-AF9-induced murine acute myeloid leukemia.	PDPK1 KMT2A	1.64e-05	4	58	2	25769952
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	ILF3 DDX17 KMT2A NOP2 ATP2B1	2.24e-05	202	58	5	24639526
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	RALY FLNA KMT2C ILF3 DDX17 KMT2A NOP2 RPL15	2.28e-05	711	58	8	33022573
Pubmed	Genomic code for Sox2 binding uncovers its regulatory role in Six3 activation in the forebrain.	SIX3 SIX6	2.72e-05	5	58	2	23792023
Pubmed	Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders.	SIX3 SIX6	2.72e-05	5	58	2	26034287
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNC	2.72e-05	5	58	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNC	2.72e-05	5	58	2	12006559
Pubmed	The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation.	SIX3 SIX6	2.72e-05	5	58	2	19146846
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNC	2.72e-05	5	58	2	17360453
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	RALY FLNA FLNC MRPL44 MLPH	2.96e-05	214	58	5	22199357
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	NOLC1 ILF3 DDX17 NOP2 RPL15	3.38e-05	220	58	5	34091597
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	ILF3 DDX17 NOP2 RPL15	3.40e-05	109	58	4	29511296
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	NOLC1 FLNA FLNC ILF3 DDX17 DDX42 DDX51 NOP2 RPL15	3.58e-05	989	58	9	36424410
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RALY NOLC1 DDX17 MRPL44 C19orf47 DDX51 NOP2 AGTPBP1	3.63e-05	759	58	8	35915203
Pubmed	Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation.	ILF3 DDX17 NOP2 RPL15	3.78e-05	112	58	4	28416769
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	FLNA FLNC ILF3 DDX17 MRPL44 NOP2 RPL15	3.90e-05	558	58	7	27591049
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RALY NOLC1 FLNA ILF3 DDX17 TFB2M NOP2 F5 MECP2 RPL15	3.95e-05	1257	58	10	36526897
Pubmed	Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function.	SIX3 SIX6	4.08e-05	6	58	2	16470613
Pubmed	Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.	SIX3 SIX6	4.08e-05	6	58	2	12050133
Pubmed	Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.	SIX3 SIX6	4.08e-05	6	58	2	20074369
Pubmed	The expression profile and clinic significance of the SIX family in non-small cell lung cancer.	SIX3 SIX6	4.08e-05	6	58	2	27821176
Pubmed	Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development.	SIX3 SIX6	4.08e-05	6	58	2	19900183
Pubmed	Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.	FLNA FLNC	4.08e-05	6	58	2	9006895
Pubmed	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.	FLNA FLNC	4.08e-05	6	58	2	12679033
Pubmed	Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication.	RALY ILF3 NOP2 RPL15	5.11e-05	121	58	4	34029587
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	KMT2C PDPK1 KMT2A	5.18e-05	43	58	3	33472061
Pubmed	Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.	NOLC1 ILF3 DDX17 TAF4	5.45e-05	123	58	4	35583604
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KMT2C KDM3B KMT2A	5.55e-05	44	58	3	24183668
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	FLNA FLNC ILF3 DDX17 BAZ2A MRPL44 NOP2 RPL15	5.68e-05	809	58	8	32129710
Pubmed	HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.	FLNA FLNC	5.71e-05	7	58	2	26929074
Pubmed	Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.	SIX3 SIX6	5.71e-05	7	58	2	18836447
Pubmed	Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.	KMT2C KMT2A	5.71e-05	7	58	2	36598580
Pubmed	Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.	KMT2C KMT2A	5.71e-05	7	58	2	26324722
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNC	5.71e-05	7	58	2	16076904
Pubmed	Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man.	SIX3 MLPH SIX6	5.94e-05	45	58	3	35951005
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	RALY NOLC1 ILF3 DDX17 NOP2 F5 RPL15	6.43e-05	604	58	7	37616343
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	RALY ILF3 DDX17 DDX51 NOP2 RPL15	6.85e-05	417	58	6	36537216
Interaction	NAA40 interactions	NOLC1 FLNA FOXB1 ILF3 DDX17 BAZ2A DDX42 KDM3B KMT2A TACC1 NOP2 MECP2 RPL15 FOXL1	3.99e-07	978	57	14	int:NAA40
Interaction	MEN1 interactions	RALY NOLC1 KMT2C FOXB1 ILF3 DDX17 BAZ2A DDX42 KDM3B KMT2A DDX51 NOP2 RPL15	4.47e-06	1029	57	13	int:MEN1
Interaction	ZNF385D interactions	ZNF385D RPL15	7.86e-06	2	57	2	int:ZNF385D
Interaction	TLE3 interactions	FLNA FOXB1 DDX17 KMT2A TAF4 SIX3 FOXL1 SIX6	1.01e-05	376	57	8	int:TLE3
Interaction	MTDH interactions	RALY FLNA FLNC ILF3 MRPL44 NOP2 MLPH MECP2 RPL15	1.12e-05	505	57	9	int:MTDH
Interaction	DDX51 interactions	ILF3 DDX51 NOP2 MECP2 RPL15	1.35e-05	108	57	5	int:DDX51
Interaction	SSRP1 interactions	RALY NOLC1 ILF3 DDX17 DDX42 KMT2A CHCHD1 NOP2 ATP2B1 MECP2	1.96e-05	685	57	10	int:SSRP1
Interaction	BRIX1 interactions	NOLC1 H1-8 ILF3 CHCHD1 NOP2 MECP2 RPL15	2.11e-05	300	57	7	int:BRIX1
Interaction	KCNA3 interactions	KMT2C ILF3 DDX17 CEP95 ZDHHC5 ARHGEF12 KMT2A FCHO2 ATP2B1 SHC3 RPL15	2.75e-05	871	57	11	int:KCNA3
Interaction	MRPL45 interactions	FOXB1 ILF3 MRPL44 CHCHD1 MECP2 FOXL1	3.01e-05	213	57	6	int:MRPL45
Interaction	NOL8 interactions	ILF3 DDX51 NOP2 MECP2 RPL15	3.07e-05	128	57	5	int:NOL8
Interaction	NLE1 interactions	FLNA DDX17 BAZ2A TAF4 MECP2 RPL15	4.40e-05	228	57	6	int:NLE1
Interaction	CHD3 interactions	NOLC1 FLNA ILF3 DDX17 DDX42 C19orf47 KMT2A DDX51 NOP2 RPL15	4.60e-05	757	57	10	int:CHD3
Interaction	SF3A3 interactions	FLNC FOXB1 DDX17 DDX42 TAF4 MECP2 RPL15	4.69e-05	340	57	7	int:SF3A3
Interaction	LMNB2 interactions	FOXB1 TRNAU1AP KDM3B DDX51 MECP2 FOXL1	5.09e-05	234	57	6	int:LMNB2
Interaction	RRS1 interactions	NOLC1 H1-8 ILF3 CHCHD1 NOP2 MECP2 RPL15	5.14e-05	345	57	7	int:RRS1
Interaction	PHB1 interactions	FLNA FLNC ILF3 DDX17 MRPL44 CHCHD1 TFB2M NOP2 ATP2B1 MECP2 RPL15 FOXL1	5.80e-05	1123	57	12	int:PHB1
Interaction	RALY interactions	RALY FOXB1 ILF3 DDX17 CHCHD1 MECP2 FOXL1	6.26e-05	356	57	7	int:RALY
Interaction	CHCHD1 interactions	RALY NOLC1 BAZ2A MRPL44 CHCHD1 NOP2	6.27e-05	243	57	6	int:CHCHD1
Interaction	MRPL38 interactions	RALY FOXB1 ILF3 MRPL44 KDM3B FOXL1	6.86e-05	247	57	6	int:MRPL38
Interaction	PRC1 interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 DDX51 NOP2 MECP2 ARHGAP33 RPL15	7.52e-05	973	57	11	int:PRC1
Interaction	RPL36 interactions	RALY ILF3 DDX42 KMT2A DDX51 NOP2 MECP2 RPL15	8.15e-05	504	57	8	int:RPL36
Interaction	KAT6A interactions	RALY FLNA ILF3 DDX17 KMT2A DDX51 NOP2 RPL15	8.85e-05	510	57	8	int:KAT6A
Interaction	RRP8 interactions	H1-8 ILF3 DDX51 NOP2 MECP2 RPL15	8.91e-05	259	57	6	int:RRP8
Interaction	RPL15 interactions	NOLC1 ZNF385D H1-8 ILF3 DDX51 NOP2 MECP2 RPL15	1.15e-04	530	57	8	int:RPL15
Interaction	NR2C2 interactions	RALY NOLC1 FLNA ILF3 DDX17 BAZ2A C19orf47 KDM3B KMT2A TAF4 NOP2 RPL15 FOXL1	1.16e-04	1403	57	13	int:NR2C2
Interaction	NUPR1 interactions	RALY NOLC1 FLNA ILF3 DDX17 DDX42 ZDHHC5 NOP2 F5	1.17e-04	683	57	9	int:NUPR1
Interaction	CDK9 interactions	RALY FLNA ILF3 DDX17 DDX42 KMT2A NOP2 MECP2 RPL15	1.20e-04	685	57	9	int:CDK9
Interaction	TLE4 interactions	FOXB1 SIX3 FOXL1 SIX6	1.34e-04	92	57	4	int:TLE4
Interaction	MRPL20 interactions	FOXB1 ILF3 MRPL44 CHCHD1 MECP2	1.39e-04	176	57	5	int:MRPL20
Interaction	MPHOSPH8 interactions	NOLC1 ILF3 NOP2 MECP2	1.39e-04	93	57	4	int:MPHOSPH8
Interaction	CEBPZ interactions	NOLC1 ILF3 DDX17 NOP2 MECP2 RPL15	1.39e-04	281	57	6	int:CEBPZ
Interaction	NOC2L interactions	FOXB1 ILF3 NOP2 MECP2 RPL15 FOXL1	1.42e-04	282	57	6	int:NOC2L
Interaction	RBBP5 interactions	FLNA KMT2C PDPK1 KMT2A TAF4 MECP2	1.56e-04	287	57	6	int:RBBP5
Interaction	BRCA1 interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 TRNAU1AP DDX42 ZDHHC5 POMGNT1 NOP2 RPL15	1.60e-04	1249	57	12	int:BRCA1
Interaction	METTL14 interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 NOP2 RPL15	1.64e-04	558	57	8	int:METTL14
Interaction	NOP2 interactions	NOLC1 H1-8 DDX51 CHCHD1 NOP2 MECP2 RPL15	1.65e-04	416	57	7	int:NOP2
Interaction	CHMP4B interactions	NOLC1 FLNA FLNC ILF3 DDX17 KDM3B NOP2 MECP2 RPL15	1.88e-04	727	57	9	int:CHMP4B
Interaction	SURF6 interactions	H1-8 ILF3 DDX51 CHCHD1 NOP2 MECP2 RPL15	1.91e-04	426	57	7	int:SURF6
Interaction	OBSL1 interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 DDX42 NOP2 AGTPBP1 RPL15	1.95e-04	902	57	10	int:OBSL1
Interaction	SENP3 interactions	ILF3 DDX17 PDPK1 KMT2A DDX51 RPL15	2.02e-04	301	57	6	int:SENP3
Interaction	NIFK interactions	NOLC1 ILF3 KBTBD6 CHCHD1 NOP2 MECP2 RPL15	2.05e-04	431	57	7	int:NIFK
Interaction	URB2 interactions	ILF3 NOP2 MECP2 RPL15	2.06e-04	103	57	4	int:URB2
Interaction	MECP2 interactions	RALY NOLC1 FLNC ILF3 DDX17 MRPL44 DDX42 DDX51 NOP2 MECP2 ARHGAP33 RPL15	2.11e-04	1287	57	12	int:MECP2
Interaction	SIRT7 interactions	NOLC1 FLNA FLNC BAZ2A DDX42 KMT2A DDX51 NOP2 RPL15	2.23e-04	744	57	9	int:SIRT7
Interaction	PLXNB1 interactions	ARHGEF12 KMT2A MECP2	2.44e-04	43	57	3	int:PLXNB1
Interaction	BBX interactions	ILF3 NOP2 MECP2 RPL15	2.48e-04	108	57	4	int:BBX
Interaction	PML interactions	NOLC1 FLNA FLNC ILF3 DDX42 KDM3B KMT2A TAF4 NOP2 RPL15	2.57e-04	933	57	10	int:PML
Interaction	H1-8 interactions	H1-8 NOP2 RPL15	2.62e-04	44	57	3	int:H1-8
Interaction	TTF1 interactions	ILF3 BAZ2A NOP2 RPL15	2.66e-04	110	57	4	int:TTF1
Interaction	ZBTB2 interactions	RALY NOLC1 ILF3 DDX17 BAZ2A NOP2 MECP2	2.66e-04	450	57	7	int:ZBTB2
Interaction	CHD4 interactions	NOLC1 ILF3 DDX17 BAZ2A PDPK1 DDX42 KMT2A NOP2 MECP2 RPL15	2.68e-04	938	57	10	int:CHD4
Interaction	YY1 interactions	FOXB1 ILF3 DDX42 KMT2A TAF4 MECP2 FOXL1	2.81e-04	454	57	7	int:YY1
Interaction	WDR36 interactions	NOLC1 ILF3 CHCHD1 NOP2 MECP2	3.02e-04	208	57	5	int:WDR36
Interaction	WDR82 interactions	FLNA KMT2C DDX42 KMT2A MECP2	3.37e-04	213	57	5	int:WDR82
Interaction	DUX4 interactions	FLNA ILF3 DDX17 NOP2 RPL15	3.44e-04	214	57	5	int:DUX4
Interaction	SCARNA22 interactions	NOLC1 ILF3 DDX17 MECP2	3.47e-04	118	57	4	int:SCARNA22
Interaction	TRIM64 interactions	FLNA NOP2	3.49e-04	10	57	2	int:TRIM64
Interaction	PMFBP1 interactions	TACC1 RPL15	3.49e-04	10	57	2	int:PMFBP1
Interaction	FBXW11 interactions	RALY FLNA FLNC ILF3 TACC1 DNAJB5 GARRE1	3.60e-04	473	57	7	int:FBXW11
Interaction	BMS1 interactions	ILF3 CHCHD1 NOP2 MECP2 RPL15	3.75e-04	218	57	5	int:BMS1
Interaction	CENPV interactions	ILF3 CHCHD1 NOP2 MECP2	3.82e-04	121	57	4	int:CENPV
Interaction	NUP50 interactions	BAZ2A DDX42 KDM3B KMT2A TAF4 MECP2	3.94e-04	341	57	6	int:NUP50
Interaction	SNRNP40 interactions	RALY FLNA ILF3 DDX17 BAZ2A KMT2A TAF4 MECP2	4.02e-04	637	57	8	int:SNRNP40
Interaction	RPP40 interactions	RALY ILF3 MECP2	4.06e-04	51	57	3	int:RPP40
Interaction	MTF1 interactions	ILF3 DDX17 NOP2 RPL15	4.06e-04	123	57	4	int:MTF1
Interaction	SIX6 interactions	SIX3 SIX6	4.25e-04	11	57	2	int:SIX6
Interaction	MAMDC2 interactions	FLNA MECP2	4.25e-04	11	57	2	int:MAMDC2
Interaction	POLR1G interactions	NOLC1 KMT2A DDX51 NOP2 MECP2 AGTPBP1 RPL15	4.39e-04	489	57	7	int:POLR1G
Interaction	RCL1 interactions	DDX42 ARHGEF12 CHCHD1 MECP2	4.45e-04	126	57	4	int:RCL1
Interaction	SMC5 interactions	NOLC1 FLNA ILF3 DDX17 BAZ2A DDX42 KMT2A TAF4 NOP2 MECP2	4.45e-04	1000	57	10	int:SMC5
Interaction	PHF20 interactions	KMT2C DDX42 KMT2A	4.55e-04	53	57	3	int:PHF20
Interaction	FOXC1 interactions	RALY ILF3 DDX17 MECP2 FOXL1	4.60e-04	228	57	5	int:FOXC1
Interaction	U2AF2 interactions	RALY FLNA ILF3 DDX17 DDX42 CHCHD1 MECP2 RPL15	4.64e-04	651	57	8	int:U2AF2
Interaction	PIAS1 interactions	NOLC1 FLNA FLNC DDX17 RPL15 BAHCC1	4.73e-04	353	57	6	int:PIAS1
Interaction	UTP14A interactions	NOLC1 ILF3 CHCHD1 NOP2 MECP2	4.79e-04	230	57	5	int:UTP14A
Interaction	CCDC8 interactions	RALY FLNA ILF3 DDX17 C19orf47 NOP2 F5 ATP2B1	4.88e-04	656	57	8	int:CCDC8
Interaction	NPHP1 interactions	FLNA FLNC FCHO2 ATP2B1	5.01e-04	130	57	4	int:NPHP1
Interaction	FAHD2B interactions	FAHD2B FAHD2A	5.09e-04	12	57	2	int:FAHD2B
Interaction	ITGB2 interactions	FLNA FLNC KMT2A RPL15	5.31e-04	132	57	4	int:ITGB2
Interaction	RPF1 interactions	H1-8 NOP2 MECP2 RPL15	5.31e-04	132	57	4	int:RPF1
Interaction	RANBP2 interactions	RALY FLNA FOXB1 DDX17 MECP2 FOXL1	5.33e-04	361	57	6	int:RANBP2
Interaction	CUL7 interactions	RALY NOLC1 FLNA ILF3 DDX17 DDX42 CHCHD1 NOP2 RPL15	5.66e-04	845	57	9	int:CUL7
Interaction	URB1 interactions	ILF3 NOP2 MECP2 RPL15	5.78e-04	135	57	4	int:URB1
Interaction	RBM5 interactions	ILF3 DDX17 MECP2 RPL15	5.78e-04	135	57	4	int:RBM5
Interaction	RBM28 interactions	ILF3 DDX17 CHCHD1 NOP2 MECP2 RPL15	5.89e-04	368	57	6	int:RBM28
Interaction	GTPBP10 interactions	ILF3 CHCHD1 NOP2 MECP2	5.94e-04	136	57	4	int:GTPBP10
Interaction	DGCR8 interactions	RALY ILF3 DDX17 NOP2 MECP2	6.03e-04	242	57	5	int:DGCR8
Interaction	CIT interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 DDX42 KMT2A DDX51 TFB2M NOP2 RPL15	6.26e-04	1450	57	12	int:CIT
Interaction	TARDBP interactions	RALY ILF3 DDX17 MRPL44 NOP2 MECP2 RPL15	6.33e-04	520	57	7	int:TARDBP
Interaction	PDS5A interactions	FLNA FOXB1 KDM3B MECP2 FOXL1	6.38e-04	245	57	5	int:PDS5A
Interaction	AATF interactions	RALY NOLC1 ILF3 DDX17 CHCHD1 NOP2	6.59e-04	376	57	6	int:AATF
Interaction	CHMP4C interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 NOP2 RPL15	6.61e-04	687	57	8	int:CHMP4C
Interaction	KIF20A interactions	RALY NOLC1 FLNA FLNC ILF3 DDX17 TRIM75 DDX51 NOP2 RPL15	6.62e-04	1052	57	10	int:KIF20A
Interaction	CBX8 interactions	ILF3 BAZ2A KMT2A NOP2 MECP2	6.86e-04	249	57	5	int:CBX8
Interaction	CYLD interactions	FLNA FLNC ILF3 DDX17 MRPL44 ARHGEF12 NOP2 GARRE1 RPL15	6.86e-04	868	57	9	int:CYLD
Interaction	RNF113A interactions	NOLC1 FLNA ILF3 DDX17 TFB2M TAF4 NOP2 RPL15	6.94e-04	692	57	8	int:RNF113A
Interaction	TOP1 interactions	RALY ILF3 DDX17 DDX42 KMT2A NOP2 MECP2 RPL15	7.20e-04	696	57	8	int:TOP1
Interaction	ELF5 interactions	KMT2C FLNC ILF3 RPL15	7.95e-04	147	57	4	int:ELF5
Interaction	ZNF48 interactions	ILF3 TACC1 NOP2 RPL15	8.36e-04	149	57	4	int:ZNF48
Cytoband	2q11.2	FAHD2B FAHD2A VWA3B	1.02e-04	72	57	3	2q11.2
Cytoband	17q23.3	CEP95 DDX42	6.44e-04	30	57	2	17q23.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q11	FAHD2B FAHD2A VWA3B	9.31e-04	153	57	3	chr2q11
GeneFamily	SINE class homeoboxes	SIX3 SIX6	5.43e-05	6	35	2	525
GeneFamily	DEAD-box helicases	DDX17 DDX42 DDX51	7.24e-05	42	35	3	499
GeneFamily	Forkhead boxes	FOXB1 FOXB2 FOXL1	7.78e-05	43	35	3	508
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	BAZ2A MECP2	1.98e-04	11	35	2	1025
GeneFamily	PHD finger proteins	KMT2C BAZ2A KMT2A	6.96e-04	90	35	3	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C KMT2A	1.96e-03	34	35	2	487
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF385D FLNA FLNC H1-8 ALPK3 TACC1	1.97e-07	197	57	6	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF385D FLNA FLNC ALPK3 TACC1	5.46e-06	198	57	5	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	FLNA KMT2C ILF3 KMT2A TACC1	5.73e-06	200	57	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
Computational	Genes in the cancer module 197.	NOLC1 ILF3 KMT2A TAF4 SIX3 SIX6	7.10e-06	174	30	6	MODULE_197
Computational	Neighborhood of NUMA1	BAZ2A KDM3B KMT2A	4.92e-04	56	30	3	GCM_NUMA1
Computational	Genes in the cancer module 123.	ILF3 KMT2A TAF4 MECP2 SIX6	5.48e-04	247	30	5	MODULE_123
Drug	Antimycin A [1397-94-0]; Down 200; 7.2uM; HL60; HG-U133A	RALY BAZ2A PDPK1 TACC1 TFB2M ATP2B1	7.48e-06	188	57	6	1414_DN
Drug	Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A	DDX17 BAZ2A MRPL44 KMT2A DNAJB5 ARHGAP33	7.95e-06	190	57	6	4507_DN
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	1.02e-05	3	55	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	1.02e-05	3	55	2	DOID:0111190 (implicated_via_orthology)
Disease	Anophthalmia-microphthalmia syndrome	SIX3 SIX6	7.00e-04	21	55	2	cv:C5680330
Disease	Neurodevelopmental Disorders	KMT2C KMT2A MECP2	7.06e-04	93	55	3	C1535926
Disease	Antiglaucoma preparations and miotics use measurement	KMT2A SIX6	1.08e-03	26	55	2	EFO_0009944
Disease	factor VIII measurement, venous thromboembolism	FCHO2 F5	1.84e-03	34	55	2	EFO_0004286, EFO_0004630

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKPKPVPLRKKAIGG	TACC1	231	O75410
IKAFPRAGVKGKGPV	ZNF385D	241	Q9H6B1
ALVGKDKKGRAPIPP	BAHCC1	2281	Q9P281
VKRLRGEGLPFPKVP	DNAJB5	301	O75953
RSFKFRPKGKPCPKE	ERVK-19	216	O71037
KKLGRGPAKASPQPA	C19orf47	296	Q8N9M1
LGQPKRRGRPPSKFF	BAZ2A	1401	Q9UIF9
GIKPRKRKTFALPGI	FCHO2	281	Q0JRZ9
NRKRFAPPKPKGEAT	ALPK3	681	Q96L96
AKKGRKGSIPRTIPP	CFAP46	2391	Q8IYW2
KEPKPFVFEGKVRGP	AGTPBP1	441	Q9UPW5
REAVFGKNFIPPKKP	ATP2B1	81	P20020
KGKRRGFPSILGPPR	ARHGEF12	591	Q9NZN5
GEPKPDRPKGLKRAA	RALY	91	Q9UKM9
PAKKAAVPAKRVGLP	NOLC1	101	Q14978
QPRGSFKKPSAKPLR	FHDC1	976	Q9C0D6
FIKIPRRPDQPGKGS	FOXB2	71	Q5VYV0
PRRAGEAKGKGPKKP	H1-8	146	Q8IZA3
APKGPRKAGLPIKAS	H1-8	321	Q8IZA3
GKPAITKRKFSPGRP	KMT2C	826	Q8NEZ4
KKRKRKPYRPGIGGF	KMT2C	1271	Q8NEZ4
DGFAVPEPPKRKKSR	DDX42	921	Q86XP3
QFPKAKLKPGAPVRS	FLNC	256	Q14315
KGKQAPKGRPRTAPL	KDM3B	861	Q7LBC6
PGVGVFRKPPVFLKK	FAHD2A	281	Q96GK7
KPERKFAPPRKFFPG	MCIDAS	36	D6RGH6
FIKIPRRPDQPGKGS	FOXB1	71	Q99853
PSVKGKPGKRLSAPR	ARHGAP33	26	O14559
ARFGNPRKPVLKPNK	CHCHD1	11	Q96BP2
KSLGRFPNGKVKEPP	CR2	216	P20023
FPNGKVKEPPILRVG	CR2	221	P20023
PGVGVFRKPPVFLKK	FAHD2B	281	Q6P2I3
FGKRKAPKVQPFLPR	DDX51	166	Q8N8A6
RPKLNPKKARAYGPG	FLNA	276	P21333
KGFKAFPGKGERRPA	GARRE1	1051	O15063
KKRAPVPVRGGPKFA	ILF3	601	Q12906
AQVQGPRTRKPPKGK	CEP95	326	Q96GE4
CFVKVPREKGRPGKG	FOXL1	106	Q12952
KSIEKKRGRPPTFPG	KMT2A	216	Q03164
KRGRPPTFPGVKIKI	KMT2A	221	Q03164
PPKKFGNPGERLRKK	DDX17	106	Q92841
KFVDPSRRAPPGKCK	HHIPL2	596	Q6UWX4
SRRAPPGKCKYKPVP	HHIPL2	601	Q6UWX4
KPSGKPRRKSNLPIF	MLPH	501	Q9BV36
PRGGKRPKKIHKPTV	KBTBD6	16	Q86V97
PQAIPKKRGRKPGSV	MECP2	261	P51608
AIGPRKKRKVDCPGP	TAF4	1011	O00268
APKLVPPVRGVKKGF	MRPL44	21	Q9H9J2
NGKPLPGATPAKRFK	TRNAU1AP	66	Q9NX07
KPGKQSGHPKFPRVR	F5	991	P12259
PPQPRKKRPEDFKFG	PDPK1	71	O15530
PSPLIKPFGARKKRS	POMGNT1	6	Q8WZA1
AVPGAKGAFKKRKPP	SHC3	191	Q92529
GPVDKYRVRKKFPLP	SIX3	186	O95343
PLGPVDKYRVRKKFP	SIX6	106	O95475
FFKLDPRSGGVIKPP	TFB2M	151	Q9H5Q4
SLFNAPRGKKRPAPG	NOP2	96	P46087
RKRPVPKGATYGKPV	RPL15	71	P61313
PLQGPRARFRKKPKA	ROBO3	1241	Q96MS0
PGFPKRFTVKPVVLG	TRIM75	326	A6NK02
GKTPLGRPAVPRFGK	ZDHHC5	596	Q9C0B5
RKLKGKLPPGAGVRE	VWA3B	321	Q502W6
LPAVKIPKKRGRKPG	SCML4	36	Q8N228