Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

TBXAS1 PECR PTGR2

1.24e-0434573GO:0016628
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

TBXAS1 PECR PTGR2

7.40e-0462573GO:0016627
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

NEIL2 ASAH2 LCT KLB

7.62e-04144574GO:0016798
GeneOntologyMolecularFunctioncalcium ion binding

TGM2 EYS ASAH2 PKD2L1 ADGRE5 CLSTN2 DYSF GSN

1.23e-03749578GO:0005509
GeneOntologyMolecularFunctionhexosyltransferase activity

GALNT9 FUT1 B4GALT5 PIGM

3.09e-03211574GO:0016758
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

ASAH2 LCT KLB

3.19e-03103573GO:0004553
DomainGLYCOSYL_HYDROL_F1_2

LCT KLB

9.42e-055582PS00653
DomainGLYCOSYL_HYDROL_F1_1

LCT KLB

9.42e-055582PS00572
DomainGlyco_hydro_1

LCT KLB

9.42e-055582PF00232
DomainGlyco_hydro_1

LCT KLB

9.42e-055582IPR001360
DomainVillin/Gelsolin

FLII GSN

2.62e-048582IPR007122
DomainGEL

FLII GSN

2.62e-048582SM00262
DomainGelsolin

FLII GSN

8.42e-0414582PF00626
DomainGelsolin-like_dom

FLII GSN

8.42e-0414582IPR007123
DomainADF-H/Gelsolin-like_dom

FLII GSN

2.50e-0324582IPR029006
Domain-

FLII GSN

2.50e-03245823.40.20.10
DomainGroES-like

ZDHHC6 PTGR2

2.50e-0324582IPR011032
Domain-

LCT KLB

5.28e-03355823.20.20.80
DomainGlyco_hydro_catalytic_dom

LCT KLB

6.20e-0338582IPR013781
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

ASAH2 FUT1 ARSG B4GALT5

1.97e-0553434MM14647
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

ASAH2 FUT1 ARSG B4GALT5

2.82e-0558434M576
PathwayREACTOME_SPHINGOLIPID_METABOLISM

ASAH2 FUT1 ARSG B4GALT5

1.73e-0492434MM15086
PathwayREACTOME_SPHINGOLIPID_METABOLISM

ASAH2 FUT1 ARSG B4GALT5

3.08e-04107434M14857
Pubmed

Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells.

LAMP2 FUT1

8.77e-06360227560716
Pubmed

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

CNOT4 CNOT8

6.11e-05760210637334
Pubmed

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.

CNOT4 CNOT8

6.11e-05760230692204
Pubmed

The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins.

HTR2C PATJ

8.14e-05860214988405
Pubmed

A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.

FLII GSN

1.05e-04960237126682
Pubmed

The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.

CYP26B1 RDH11

1.05e-04960224733397
Pubmed

Human Ccr4-Not complexes contain variable deadenylase subunits.

CNOT4 CNOT8

1.91e-041260219558367
Pubmed

Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation.

CNOT4 CNOT8

1.91e-041260231320642
Pubmed

l7Rn6 encodes a novel protein required for clara cell function in mouse lung development.

EED LAMP2

1.91e-041260216157679
Pubmed

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome.

CYP26B1 GCM2

2.26e-041360216399080
Pubmed

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.

OCA2 SLC1A2

4.91e-041960222561518
Pubmed

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.

CLSTN2 LCT

6.61e-042260219174780
Pubmed

Human gingiva transcriptome during wound healing.

TGM2 MMP10 DYSF

8.53e-0410760328005267
Pubmed

Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands.

CYP26B1 RDH11

8.56e-042560231562240
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TGM2 ZDHHC6 LAMP2 ADGRE5 BACE2 PPP6R2 B4GALT5 ITFG1

1.03e-03120160835696571
Pubmed

Genetic risk profiling and prediction of disease course in Crohn's disease patients.

CLSTN2 LCT

1.07e-032860219422935
Pubmed

Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.

EED CYP26B1

1.15e-032960228049658
Pubmed

HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.

RDH11 DYSF GSN

1.67e-0313560323874603
Pubmed

Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging.

LAMP2 KLB

1.68e-033560230818059
Cytoband17q24.2

ABCA9 ARSG

7.14e-043060217q24.2
GeneFamilyGelsolin/villins

FLII GSN

1.33e-048402950
GeneFamilyCCR4-NOT transcription complex

CNOT4 CNOT8

2.59e-04114021023
GeneFamilyShort chain dehydrogenase/reductase superfamily

PECR RDH11

1.23e-0276402743
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 EYS PDE6A TSEN54 BACE2 B4GALT5

1.09e-071725963a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 EYS PDE6A TSEN54 BACE2 B4GALT5

1.09e-07172596cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 SEL1L2 FUT1 TEAD4 DYSF

3.96e-061795959fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EYS ZFHX3 CLSTN2 ABCA9 GSN

5.44e-0619159570c067c54084bfb02c29bab085f4defd477194fb
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Early_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYP26B1 ULBP1 TEAD4 MMP10 DYSF

5.58e-061925954986ef70a665fdfa1df86f7f8a15117487eae159
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TGM2 BACE2 SLC13A2 B4GALT5 GSN

6.17e-06196595057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TGM2 CYP26B1 FUT1 MMP10 DYSF

6.17e-0619659585b697db1c925eff8bbef9d74565c82be5a0ddcc
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TGM2 BACE2 SLC13A2 B4GALT5 GSN

6.32e-061975953f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

3.58e-05140594b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYS HTR2C SEL1L2 NKAIN3

4.68e-051505940205318a870e091add66ee4305747dda9f51510d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 FSCN3 CDC14A WDR49

5.32e-0515559490e629681a72baacc7981b82883866a487638dbc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 FSCN3 CDC14A WDR49

5.32e-05155594e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 FSCN3 CDC14A WDR49

5.32e-051555945a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMEL1 CYP26B1 PKD2L1 SLC1A2

5.73e-05158594f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMEL1 CYP26B1 PKD2L1 SLC1A2

5.73e-051585948c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

EYS PDE6A SEL1L2 NKAIN3

6.47e-0516359419c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 CLSTN2 LCT KLB

7.11e-051675943dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 CLSTN2 LCT KLB

7.11e-0516759495b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 CLSTN2 LCT KLB

7.11e-051675949480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCelldroplet-Lung-21m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBXAS1 NEURL1 ZFHX3 ABCA9

7.27e-05168594aaafa7243c44e6852d92e3445335fc4a1018f416
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 PKD2L1 CDC14A WDR49

7.97e-05172594381ae1c3c07d0a424f43455ec571653b192a946a
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 NEURL1 ZFHX3 ABCA9

8.15e-0517359431ea04e65876c42b90245d280f0b6439bfffbace
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 NEURL1 ZFHX3 ABCA9

8.15e-051735941cff815536f620e32b9805666e1aa711462c2d25
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 PKD2L1 CDC14A WDR49

8.33e-05174594dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 BACE2 DYSF CDC14A

8.71e-051765945386386619cf173939d3c117b20e6f27ab397993
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 BACE2 DYSF CDC14A

8.71e-05176594820edade963768e4bfd86b554da4cd7100567ac8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 PKD2L1 CDC14A WDR49

9.29e-051795947394e77e665bf16d3733df91bb12907be460ab44
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

9.29e-05179594fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FMN1 PKD2L1 CLSTN2 OCA2

9.29e-0517959453e700494d251ec5649b2dea5fc7d5aeeeed572b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

9.29e-051795947db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

9.50e-05180594b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

9.70e-051815940513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

9.70e-051815942b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 PKD2L1 CDC14A WDR49

9.70e-051815945bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 PKD2L1 CDC14A WDR49

9.70e-051815948e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC6 OCA2 CDC14A WDR49

1.01e-04183594848fc6dd129150897ee339343e83c645b6e779eb
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

1.01e-04183594e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

1.03e-04184594ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TGM2 ZFHX3 BACE2 GSN

1.06e-041855947dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBXAS1 TGM2 ZFHX3 BACE2

1.06e-041855949f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CYP26B1 FUT1 MMP10 DYSF

1.08e-041865940cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

TBXAS1 MMEL1 TEAD4 GSN

1.08e-04186594acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TGM2 ZFHX3 BACE2 GSN

1.10e-041875945258674d0346e5c51a4b965efcdc1790c970845d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TBXAS1 TGM2 ZFHX3 BACE2

1.10e-0418759413731298bc562ec29582f5da1b4c97261284f6f1
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMN1 CLSTN2 PATJ SLC13A2

1.12e-041885944bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM2 MMEL1 BACE2 GSN

1.12e-041885945901b276f2379abf486b8285957277e95f08464e
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FUT1 TEAD4 MMP10 DYSF

1.12e-04188594986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TBXAS1 PKD2L1 ADGRE5 WDR49

1.12e-04188594d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TGM2 ZFHX3 BACE2 GSN

1.15e-041895944f9608b84d135268a17455661870c46ae8554a24
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CYP26B1 FUT1 MMP10 DYSF

1.15e-041895944bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TBXAS1 ZFHX3 CDC14A GSN

1.15e-0418959442ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PECR SLC1A2 GSN KLB

1.17e-04190594b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMN1 OXNAD1 PATJ CDC14A

1.19e-04191594142f98cabf8737b28369315b3d7a0797ded88e03
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TGM2 CYP26B1 MMP10 DYSF

1.19e-0419159454029b68fb78163c969890886ab0f8fb0dcf3c20
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.22e-04192594356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMN1 OXNAD1 PATJ CDC14A

1.22e-041925947ab626a516b07d899175ff12f1c8257688324e4b
ToppCellmild_COVID-19_(asymptomatic)-CD4+_Tcm|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FMN1 OXNAD1 PATJ CDC14A

1.24e-04193594498d3a83bce6deff69aea71b18a43688e0a8ed7d
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMN1 OXNAD1 PATJ CDC14A

1.24e-04193594194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

FMN1 OXNAD1 PATJ CDC14A

1.24e-04193594725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellLA|World / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.24e-04193594d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.24e-04193594dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMN1 OXNAD1 PATJ CDC14A

1.24e-04193594c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP26B1 CLSTN2 SLC1A2 ABCA9

1.24e-04193594261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.27e-0419459411c79a8c56ece42713b04b321982e41e239f07a5
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.27e-04194594014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellRA|World / Chamber and Cluster_Paper

TGM2 BACE2 WDR49 GSN

1.27e-0419459408f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMN1 OXNAD1 PATJ CDC14A

1.27e-04194594a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TGM2 CYP26B1 FUT1 DYSF

1.29e-0419559454fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.29e-04195594a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.29e-041955946a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 CLSTN2 SEL1L2 DYSF

1.32e-04196594b71d711be5609115b00a57700885aca608920896
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM2 MMEL1 BACE2 GSN

1.32e-04196594020110cd79453df9546fb20802fe38ecadd9fe74
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Early_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYP26B1 ULBP1 TEAD4 DYSF

1.32e-041965940f00aac6dac699507ce336020b2e96fd192de0be
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

ZFHX3 CLSTN2 ABCA9 GSN

1.32e-04196594e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 CLSTN2 SLC1A2 ABCA9

1.34e-04197594b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 CLSTN2 SLC1A2 ABCA9

1.34e-04197594c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell21-Trachea-Epithelial-Club-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

BACE2 SLC13A2 B4GALT5 GSN

1.37e-04198594e735d82e5151c98b5724c543f8ad633c8ed824d2
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A2 ARSG GSN ITFG1

1.37e-04198594a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 ULBP1 ADGRE5 SLC13A2

1.37e-041985942b724d2a36843801984d46a969d33149b76c9771
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMP2 DYSF B4GALT5 GSN

1.37e-04198594df546a9afc0e15398f33c1b511c7281771f9aea0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM2 MMEL1 BACE2 GSN

1.37e-04198594778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM2 MMEL1 BACE2 GSN

1.37e-041985947896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 CYP26B1 DYSF GSN

1.40e-041995948b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMP2 DYSF B4GALT5 GSN

1.40e-04199594b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCellNeuronal-Excitatory-eD(FEZF2)|Neuronal / cells hierarchy compared to all cells using T-Statistic

HTR2C ZFHX3 CLSTN2 SLC1A2

1.42e-042005941b485ff2435c6732be58cbc9eb2f5c273f9c4bf2
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMP2 DYSF B4GALT5 GSN

1.42e-04200594808571d74bb5c4d765ff13fc9393f88020d4e90d
DrugPyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A

TGM2 EED ASAP3 TEAD4 PPP6R2 GSN

1.20e-051975962839_UP
DrugDexamethasone acetate [1177-87-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A

TGM2 ADGRE5 CLSTN2 PATJ CDC14A CNOT4

1.23e-051985962242_DN
DrugCaffeic acid [3331-39-5]; Up 200; 22.2uM; PC3; HT_HG-U133A

HTR2C FSCN3 ULBP1 PATJ LCT CDC14A

1.27e-051995966753_UP
DiseaseColorectal Carcinoma

TGM2 NEURL1 ASAP3 CLSTN2 CDC14A WDR49 ABCA9

4.39e-04702587C0009402
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

ZFHX3 TEAD4

7.05e-0420582EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Diseaseenergy expenditure

TBXAS1 PATJ

1.29e-0327582EFO_0005109
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS PDE6A

1.29e-0327582DOID:10584 (implicated_via_orthology)
Diseasecardiac arrhythmia

NEURL1 ZFHX3

1.59e-0330582EFO_0004269
Diseasecolorectal adenoma

CYP26B1 BACE2

1.93e-0333582EFO_0005406

Protein segments in the cluster

PeptideGeneStartEntry
SPLQGKDWVFFQSFI

ERVPABLB-1

101

P60509
FESENFFLPGIKWNG

BACE2

181

Q9Y5Z0
FQDGWKAAQSLFPFI

ASAP3

226

Q8TDY4
ENGDFNWIVPGKFLA

CDC14A

176

Q9UNH5
NGRKNSGIWSFFFLI

ABCA9

1131

Q8IUA7
SDGGRFKFPDGVQNW

HTR2C

41

P28335
LDFEQGFLWSFLGPV

ADGRE5

686

P48960
VKENTFLWFTGDNGP

ARSG

291

Q96EG1
SQEAEPVAGFKWGFL

C1orf232

156

A0A0U1RR37
WQGGEVTKPQFAQFF

CLSTN2

501

Q9H4D0
EQFRKINGFPNAFWG

B4GALT5

281

O43286
FDLKTGFCPLNSFQW

ASTE1

166

Q2TB18
WAPAGQEFASFLTKG

OCA2

61

Q04671
SEGFPWDGFNEQTPK

FMN1

626

Q68DA7
PKNWSLFAVNFFVGA

MPC2

91

O95563
VFIFKGNEFWAIRGN

MMP10

351

P09238
IFDFLGFQWAPILGN

NKAIN3

26

Q8N8D7
ENFFWVGIGAQKPYD

FLII

1141

Q13045
DKGPAQFEYVWQLGF

EYS

471

Q5T1H1
EFSTAWLQGKFQGRP

NEIL2

266

Q969S2
QGWKAATAPVVGFFD

GALNT9

231

Q9HCQ5
GLNFTQGKTEGDPFW

ASAH2

466

Q9NR71
LQTFELDGFQIPKGW

CYP26B1

376

Q9NR63
DFFAFQKEPLDESGW

PDE6A

366

P16499
WGQSFFEGSFQKIPA

PECR

216

Q9BY49
AFLQDTFPEGFLWGA

LCT

376

P09848
QFGPGFSWIANFTKA

LAMP2

91

P13473
LFGVQFNWHSKEGDP

EED

96

O75530
QSQFGLKGFNWTLFI

MMEL1

341

Q495T6
SFKAGQWVDFFIPGV

OXNAD1

91

Q96HP4
DLFQDVKWSDFGFPG

HSPBAP1

141

Q96EW2
VKWSDFGFPGRNGQE

HSPBAP1

146

Q96EW2
RKNPFSFFAGIFQAW

SLC1A2

341

P43004
SFGTFRPWGKFALNF

FSCN3

441

Q9NQT6
QFEIAWFAEPLFKTG

KLB

766

Q86Z14
GEYPSGINTWQFNFK

CNOT8

86

Q9UFF9
QFFKNWRDPDQTDGL

GSN

391

P06396
FLGWGNLAFPNAKGE

SLC13A2

351

Q13183
LGGEGNFNWRFIFPF

DYSF

1861

O75923
PEEKGWAKFTDFQPF

PPP6R2

746

O75170
QGFFAQNGVNPDWEK

MCMBP

16

Q9BTE3
FAGDGQEATPWKDFA

FUT1

281

P19526
WLFSFFIKTPQQGAQ

RDH11

251

Q8TC12
EGFVELKSPAGKFWQ

TSEN54

86

Q7Z6J9
AAEKGWPDAQFQLGF

SEL1L2

401

Q5TEA6
FWRLDGNAIFFQAKG

GCM2

141

O75603
DWQAAFGFGSSKQPE

CNOT4

386

O95628
SAKFIKNIPWNFGQF

TGM2

171

P21980
KNIPWNFGQFEDGIL

TGM2

176

P21980
NFKQVFTWSGVPEGD

ZDHHC6

271

Q9H6R6
PFIGNLTFFRQGFWE

TBXAS1

51

P24557
GFWAKALPEEFANEG

NEURL1

151

O76050
GLFPWTPKLGNEDFN

PATJ

106

Q8NI35
SQGVWGLDDFQFLPF

PTPA

241

Q15257
GLDDFQFLPFIWGSS

PTPA

246

Q15257
FNQFFIQPEEWKGGI

WDR49

266

Q8IV35
ERGPSNAFFLVKFWA

TEAD4

286

Q15561
KEEQLPFGPFNGTAW

PKD2L1

231

Q9P0L9
RGSWQFLFNGQKFLL

ULBP1

136

Q9BZM6
DFSNKGTLWGFVPFV

ITFG1

306

Q8TB96
QGKNTFLFIWLAGLF

PIGM

381

Q9H3S5
FEPGILQLSQWFKEG

PTGR2

296

Q8N8N7
ASSFGKWFEGPDQAF

ZFHX3

201

Q15911