Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class Ib protein binding

KIR2DS4 KIR2DL1 KIR2DL3

6.44e-0716223GO:0023029
GeneOntologyMolecularFunctionMHC class Ib receptor activity

KIR2DS4 KIR2DL1 KIR2DL3

1.11e-0619223GO:0032394
GeneOntologyMolecularFunctionimmune receptor activity

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL3

2.93e-05165224GO:0140375
GeneOntologyMolecularFunctionMHC protein binding

KIR2DS4 KIR2DL1 KIR2DL3

3.44e-0558223GO:0042287
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

KIR2DS4 KIR2DS5 KIR2DS2 PLXNA2 KIR2DL1 KIR2DL3 KIR2DS1

4.46e-041353227GO:0004888
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.34e-06615227GO:0002764
GeneOntologyBiologicalProcessregulation of immune response

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

9.28e-051085227GO:0050776
MousePhenoincreased T cell derived lymphoma incidence

COP1 LIG4 ZEB1

1.43e-0553133MP:0002024
MousePhenoincreased thymus tumor incidence

COP1 LIG4 ZEB1

1.52e-0554133MP:0010365
DomainImmunoglobulin

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.80e-11190218IPR013151
Domainig

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.80e-11190218PF00047
DomainIg_sub

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

9.82e-09421218IPR003599
DomainIG

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

9.82e-09421218SM00409
DomainIg-like_fold

KIR2DS4 KIR2DS5 KIR2DS2 PLXNA2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.93e-08706219IPR013783
DomainIG_LIKE

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.25e-08491218PS50835
DomainIg-like_dom

KIR2DS4 KIR2DS5 KIR2DS2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.91e-08503218IPR007110
Domain-

KIR2DS4 KIR2DS2 PLXNA2 SDK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.27e-076632182.60.40.10
DomainZnf_RING_CS

RNF10 COP1

1.43e-02163212IPR017907
DomainZnf_C3HC4_RING-type

RNF10 COP1

1.58e-02172212IPR018957
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.70e-1088186M16004
PathwayKEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.27e-08137186M5669
PathwayREACTOME_DAP12_INTERACTIONS

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DS1

2.94e-0746184M27151
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

KIR2DL1 KIR2DL2 KIR2DL3

1.81e-0541183M13519
PathwayREACTOME_DAP12_INTERACTIONS

KIR2DS4 KIR2DL1 KIR2DL3

4.16e-0554183MM14871
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS1

8.44e-05190184M8240
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

KIR2DS4 KIR2DL1 KIR2DL3

6.31e-04135183MM14781
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.12e-22822718681957
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.60e-211122719664392
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.10e-201222719936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.10e-201222719181658
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.10e-201222720371502
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.39e-201322718687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.39e-201322719934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.39e-201322719120281
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.78e-201422715896204
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.78e-201422719875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.78e-201422719421224
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522717498266
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522719326408
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522719926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522719850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522720207982
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522720082646
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522719493232
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522720643584
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.96e-201522720356536
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622719527230
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622719897003
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622720331834
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622720652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622718668235
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622716403292
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622719279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622717868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622718643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622719309280
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622719000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622720670355
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.59e-191622720210919
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DS4 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.12e-19722611169255
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722719169284
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722720173784
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722720173792
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722720878400
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722719218127
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722720483367
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722720650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722719450876
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722719968064
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.71e-191722719761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822719630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822720519398
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822720200544
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822720580654
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822719046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

4.43e-191822719846535
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

7.01e-191922718778326
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

7.01e-191922718848853
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

7.01e-191922718571006
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

7.01e-191922720600442
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.08e-182022720193031
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.62e-182122719861144
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.37e-182222720492596
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3

2.55e-1892267749980
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

6.37e-181022612559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3

1.40e-171122618830515
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.16e-172922720082482
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS1

2.80e-171222620137308
Pubmed

Diversity of the repertoire of p58 killer cell inhibitory receptors in a single individual.

KIR2DS4 KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS1

6.21e-17522510424431
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

6.21e-17522516112031
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

6.21e-17522518755860
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS4 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

9.09e-171422619489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DS1

9.09e-171422618945962
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

9.30e-173522719683555
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.74e-161722619032228
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3

5.61e-161822620210918
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DS1

1.17e-152022620426625
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2

1.30e-15722514607943
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL2 KIR2DL3

7.81e-1592258662091
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL3

4.91e-141222517490516
Pubmed

Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.20e-13422426542066
Pubmed

In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DS1

6.00e-13522419410616
Pubmed

Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1

1.80e-12622417882223
Pubmed

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.

KIR2DS4 KIR2DL1 KIR2DL2 KIR2DL3

8.39e-12822415730517
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DS4 KIR2DS2 KIR2DL2 KIR2DL3

8.39e-12822417200871
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS4 KIR2DS2 KIR2DL1 KIR2DS1

1.51e-11922418340360
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DS4 KIR2DS5 KIR2DL2 KIR2DS1

2.51e-111022421206914
Pubmed

Prognostic role of KIR genes and HLA-C after hematopoietic stem cell transplantation in a patient cohort with acute myeloid leukemia from a consanguineous community.

KIR2DS2 KIR2DL1 KIR2DS1

2.20e-10322329549293
Pubmed

Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

KIR2DS2 KIR2DL2 KIR2DL3

2.20e-10322330696053
Pubmed

Killer immunoglobulin receptor genes and their HLA-C ligand are associated with Type 1 diabetes in an Eastern Indian population.

KIR2DS4 KIR2DL2 KIR2DL3

2.20e-10322326031759
Pubmed

Associations of killer cell immunoglobulin- like receptor genes with rheumatoid arthritis.

KIR2DS2 KIR2DL2 KIR2DL3

2.20e-10322322960345
Pubmed

Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors.

KIR2DL1 KIR2DL2 KIR2DL3

2.20e-10322315879158
Pubmed

Homozygosity for killer immunoglobin-like receptor haplotype A predicts complete molecular response to treatment with tyrosine kinase inhibitors in chronic myeloid leukemia patients.

KIR2DS2 KIR2DL2 KIR2DS1

2.20e-10322323380384
Pubmed

Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer.

KIR2DS4 KIR2DS2 KIR2DL2

2.20e-10322338387251
Pubmed

Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population.

KIR2DS4 KIR2DL2 KIR2DL3

2.20e-10322332422377
Pubmed

Lack of killer immunoglobulin-like receptor 2DS2 (KIR2DS2) and KIR2DL2 is associated with poor responses to therapy of recurrent hepatitis C virus in liver transplant recipients.

KIR2DS2 KIR2DL2 KIR2DS1

2.20e-10322319877200
Pubmed

Imputation of KIR Types from SNP Variation Data.

KIR2DS2 KIR2DL2 KIR2DL3

2.20e-10322326430804
Pubmed

[Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line].

KIR2DL1 KIR2DL2 KIR2DL3

2.20e-10322319549382
Pubmed

Cutting edge: selective expression of inhibitory or activating killer cell Ig-like receptors in circulating CD4+ T lymphocytes.

KIR2DS2 KIR2DL2 KIR2DL3

2.20e-10322318292496
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL1 KIR2DL2 KIR2DL3

8.78e-10422318269867
Pubmed

B-lymphoma cells escape rituximab-triggered elimination by NK cells through increased HLA class I expression.

KIR2DL1 KIR2DL2 KIR2DL3

8.78e-10422320056126
Pubmed

[Analysis of HLA-Cw, KIR2D genetic variations in 2 Chinese populations].

KIR2DL1 KIR2DL2 KIR2DL3

8.78e-10422318543232
Pubmed

Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility.

KIR2DS2 KIR2DL2 KIR2DL3

8.78e-10422316929347
Pubmed

Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors.

KIR2DS4 KIR2DL1 KIR2DL3

8.78e-1042239378975
Pubmed

Genetic interactions of KIR and G1M immunoglobulin allotypes differ in obese from non-obese individuals with type 2 diabetes.

KIR2DS4 KIR2DL1 KIR2DL3

8.78e-10422318632158
Pubmed

Study of the KIR gene profiles and analysis of the phylogenetic relationships of Rajbanshi population of West Bengal, India.

KIR2DS4 KIR2DL1 KIR2DL3

8.78e-10422323354323
InteractionKIR3DP1 interactions

KIR2DS5 KIR2DS2 KIR2DL1

4.51e-094223int:KIR3DP1
InteractionKIR2DS3 interactions

KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2

5.10e-0920224int:KIR2DS3
InteractionKIR2DS2 interactions

KIR2DS5 KIR2DS2 KIR2DL2 KIR2DS1

6.87e-0837224int:KIR2DS2
InteractionKIR3DL1 interactions

KIR2DS2 KIR2DL1 KIR2DL2

3.21e-0713223int:KIR3DL1
InteractionKIR2DL2 interactions

KIR2DS2 KIR2DL1 KIR2DL2

3.21e-0713223int:KIR2DL2
InteractionHLA-C interactions

KIR2DS4 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.63e-06353226int:HLA-C
InteractionKIR2DS1 interactions

KIR2DS2 KIR2DS1

6.82e-064222int:KIR2DS1
InteractionLYPD2 interactions

CARS2 PLXNA2

4.08e-059222int:LYPD2
InteractionKIR2DS5 interactions

KIR2DS5 KIR2DS2

1.35e-0416222int:KIR2DS5
Cytoband19q13.4

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

5.68e-157922719q13.4
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.96e-1718207620
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.34e-07394207471
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.27e-1249226M40909
CoexpressionGSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN

KIR2DS4 KIR2DS5 KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1

9.08e-09190226M4662
CoexpressionGSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN

KIR2DS5 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3

5.69e-07199225M9885
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CD16_POS_NK_CELL

KIR2DL1 KIR2DL3

1.02e-0418222M45763
ToppCellASK454-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

BEAN1 KIR2DL1 KIR2DL2

4.91e-0517019384705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIR2DL1 KIR2DL2 KIR2DL3

5.00e-05171193adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellASK454-Immune-NK_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

BEAN1 KIR2DL1 KIR2DL2

5.09e-05172193c9e738c3540ee09b08805b1cdb66b4a0d9d40d33
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-innate_lymphocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

6.42e-05186193e84a0ba599935ca5e7af48e0fb0500e7ed195d55
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

6.42e-051861931590fe72badffc79f1d390deb3207116ac2281bb
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

6.83e-051901931f890be1ac8613a098b271945f25a58c3c2530ab
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

6.83e-05190193d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 KIR2DL1 KIR2DL3

7.16e-0519319300349d176fb6a46cbcc99c41d975651b6e9aaad4
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

7.27e-05194193ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIR2DS4 KIR2DL1 KIR2DL3

7.27e-051941933a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIR2DL1 KIR2DL2 KIR2DL3

7.49e-05196193cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCellsevere-Lymphocytic-NK_cells|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.61e-051971938bf88b10d49ac499e7d0ba5b7023909e1fd7b29a
ToppCellmild-Lymphocytic-NK_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.72e-051981931d20fc9948965de52a98f758035edfdd12cafc5f
ToppCellsevere-Lymphocytic-NK_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.72e-051981936ef22f33b43e9adceea11738e3cba0e8b59b4ec6
ToppCellcontrol-Lymphocytic-NK_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.72e-051981931c779101d0c5f29de5cc7170d784931d6e34bdcd
ToppCellmild-Lymphocytic-NK_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.72e-05198193dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCellcontrol-Lymphocytic-NK_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIR2DS4 KIR2DL1 KIR2DL3

7.84e-051991938aca7775b3d34fd26c7b23ddb23f5f2df72684b0
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.06e-03114192670c9802a59b39241abf6f2c12a3d1844c7db5e5
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Adenocarcinoma-8|TCGA-Lung / Sample_Type by Project: Shred V9

KIR2DS4 KIR2DL3

1.08e-0311519255a56828f86c004cd11d1a426a03e86246e949a3
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZEB1 NAT10

1.10e-0311619235d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-4|TCGA-Colorectal / Sample_Type by Project: Shred V9

CARS2 NAT10

1.35e-03129192003a3202053986c2eb10d5e84b90ab33b7ee37e3
ToppCellCTRL-Lymphoid-pDC|CTRL / Disease state, Lineage and Cell class

SDK2 ZEB1

1.57e-03139192bbc10812b0c5b8c85e78171c12316becde8895c3
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

ZEB1 PDE6C

1.72e-031461927fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|368C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.72e-031461920e38e1fa40b1fcd1bb61f7af7cc2206846c192ae
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|368C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.75e-031471923ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell368C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.82e-0315019217b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.84e-03151192512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.92e-03154192ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.92e-03154192a39877cdf7b441b5c953f744ed30f1d5acf4ea19
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|GI_small-bowel / Manually curated celltypes from each tissue

KIR2DL1 KIR2DL3

1.94e-031551921c67f58ed79331addbc012dab0cb09a7f350aedb
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

ZEB1 NAT10

1.94e-031551927e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPACA9 SDK2

1.94e-03155192b5d5c38b269e9318970fcce564df1c8ed7a7ccc6
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.97e-03156192e6798d2b9c2c1fc6525c24f596f25aa85a375651
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIG4 SDK2

1.97e-031561927ece590fd8f29382e349dd0e5e016d2926aeb518
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLK2 NAT10

1.97e-03156192af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.97e-03156192a1b9e7621b646d354c2ccd850ce6a4fa9ff8a026
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.99e-03157192f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCell368C-Lymphocytic-NK_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

1.99e-03157192ef5c0ace4cd500b6cc50fb7076298f3d3543b40c
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 BEAN1

2.01e-031581920edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCellfacs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 BEAN1

2.01e-031581929fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

KIR2DL1 KIR2DL2

2.04e-0315919297c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

CLK2 SPACA9

2.04e-0315919224f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

KIR2DL1 KIR2DL2

2.04e-03159192fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.07e-03160192f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellSevere-Lymphoid-NK-|Severe / Condition, Lineage, Cell class and cell subclass

KIR2DL1 KIR2DL3

2.07e-03160192d276c6cb8317d5fb19e7b4fe5238abaf0272d4c6
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.09e-03161192f7dc1e3326ab22f2eb1e94b632469a0682a3289c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.12e-031621923b89c3758835b7b9f9d4fb0bc8ed06da382fe48b
ToppCell367C-Lymphocytic-ILC-ILC-1|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.12e-0316219274cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIR2DL1 KIR2DL3

2.14e-0316319211cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.14e-03163192466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.17e-03164192ed7277f8980f96f5b3e4eed025d46d0942e123d7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.17e-03164192c4ad98106e8663caf7c1c15d30ec633d8bd8cf57
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.17e-031641924a834a7908d8aa643a2096c52430dad795898474
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARS2 NAT10

2.19e-03165192436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARS2 NAT10

2.19e-03165192242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 PDE6C

2.22e-0316619216d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 PDE6C

2.22e-0316619208d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXNA2 ZEB1

2.22e-031661928e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CLK2 SDK2

2.22e-03166192f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

BEAN1 ZEB1

2.22e-03166192c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

SDK2 KIR2DL1

2.22e-03166192aea2ae12e4746149ebc6da063ef694381c098f80
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SDK2 ZEB1

2.25e-0316719242b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

SDK2 ZEB1

2.25e-03167192d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SDK2 ZEB1

2.25e-0316719294642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

COP1 KIR2DL1

2.25e-03167192e242827999caad08b0894d88ab97bc1df41b7650
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SDK2 ZEB1

2.25e-03167192ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIR2DL1 KIR2DL3

2.27e-03168192696b31bedbc7d40817a733e8c6ec2633404be619
ToppCell367C-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.27e-0316819280233a13135fd159f5764336a1fe67fba237776b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.27e-03168192240ea32b64d86f9216785010d6b237d9adf052c9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.27e-03168192b4bb03efb601a61465260f93896c56861c588bef
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIR2DL1 KIR2DL3

2.30e-03169192a3234904d7ff8f451ca894e93badd61d75e3cd2a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.30e-03169192e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

CLDN12 SDK2

2.30e-031691926abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SDK2 KIR2DL1

2.33e-03170192776d4224a682b6c648041827efd69794f88906f0
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

PLXNA2 ZEB1

2.35e-03171192bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell356C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZEB1 KIR2DL1

2.35e-031711923d60e7ecf25e4b781ba2387671b2aad247fb75ff
ToppCellAT1-AT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CLK2 LIG4

2.35e-031711920b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLXNA2 KIR2DL1

2.35e-0317119270963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

KIR2DL1 KIR2DL3

2.35e-031711926be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|367C / Donor, Lineage, Cell class and subclass (all cells)

KIR2DL1 KIR2DL3

2.38e-031721926379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

KIR2DL1 KIR2DL3

2.38e-03172192701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.38e-03172192e3a8891694343b6b01e80a200ae338d24797e417
ToppCell15-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell|Trachea / Age, Tissue, Lineage and Cell class

KIR2DL2 KIR2DL3

2.41e-031731926884af1492e8a3bb92a33303d4d5ec3343e88b00
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIR2DL1 KIR2DL3

2.41e-0317319279d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

CLDN12 SDK2

2.41e-03173192d11705e56b6b21eec963ea224717f27680c781ed
ToppCellASK452-Immune-NK_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIR2DL1 KIR2DL2

2.44e-03174192b84e6dc1c003a677234ce3a818650ff58a45dd09
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZNF407 ZEB1

2.44e-03174192cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellHealthy_donor-Treg|World / disease group, cell group and cell class (v2)

ZEB1 ZNF563

2.44e-03174192dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

PLXNA2 SDK2

2.44e-03174192a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCellHealthy_donor-Treg|Healthy_donor / disease group, cell group and cell class (v2)

ZEB1 ZNF563

2.44e-031741921d76921c8404b5be5fbe9f3157d53578033f2ad2
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KIR2DL3

2.46e-031751928fb8c4b9e2d9b7d737f59cd9bd3dc2bca5a8dfc4
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 ZEB1

2.49e-031761929c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 ZEB1

2.49e-031761923d372c1d527fcc118d1e5809f2524fc387682472
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIR2DL1 KIR2DL3

2.49e-03176192ce85a13e10cf37f5cf38ca8b0bac6701b6d00ffd
ToppCellfacs-Skin-Telogen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPACA9 ZEB1

2.49e-031761927b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

KIR2DS4 KIR2DL1

2.49e-031761921870860a9ebe7a655c4ea8898427e1097ee23113
ToppCellwk_15-18-Hematologic_Lymphocytic-NK-Activated_NK|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIR2DL1 KIR2DL3

2.49e-031761926802ed40eb0f91674d4f0120a3d4888c8a2e9612
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIR2DL1 KIR2DL3

2.52e-03177192fcdd71e2a727ae24b726a39216ea02c06df1f593
ToppCellControl-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

SDK2 ZEB1

2.52e-03177192e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIR2DL1 KIR2DL3

2.52e-031771920f2616a81f8fbede77c860b2126e3fa826672da3
ComputationalNeighborhood of IL2RB

KIR2DS4 KIR2DS2 KIR2DL1

8.62e-0646103GNF2_IL2RB
DrugD-Au

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.77e-1177226CID000277822
DrugAa1

KIR2DS4 KIR2DS5 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.39e-1083226CID009549188
DrugAC1L1AQK

KIR2DS4 KIR2DS5 ZEB1 KIR2DL2 KIR2DL3 KIR2DS1

1.25e-09119226CID000001105
Drugpristane

KIR2DS4 KIR2DS5 ZEB1 KIR2DL2 KIR2DL3 KIR2DS1

5.48e-09152226CID000015979
Drug1xa5

KIR2DS4 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

2.54e-0893225CID000157684
Drug1c88

KIR2DS4 KIR2DS5 KIR2DL2 KIR2DL3 KIR2DS1

1.17e-07126225CID000444766
DrugNSC237521

KIR2DS4 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.48e-06210225CID000428410
DrugDNTB

KIR2DS4 KIR2DS5 KIR2DL2 KIR2DL3 KIR2DS1

1.69e-06216225CID000015325
Drug6-carboxyfluorescein diacetate

KIR2DL1 KIR2DL2 KIR2DL3

3.13e-0630223CID000151095
Drugglycoluril

KIR2DL1 KIR2DL2 KIR2DL3

1.78e-0553223CID000062347
Drugisopentenyl diphosphate

KIR2DS4 KIR2DS5 KIR2DS1

8.43e-0589223CID000001195
DrugAb-9

KIR2DL2 KIR2DL3

1.85e-0421222CID006540280
Diseaselevel of killer cell immunoglobulin-like receptor 2DS2 in blood serum

KIR2DL1 KIR2DL3

1.31e-063202OBA_2042107
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

KIR2DL1 KIR2DL3

4.56e-0515202EFO_0801746
Diseasecomplement factor D measurement

KIR2DL1 KIR2DL3

1.80e-0393202EFO_0020283
Diseasepursuit maintenance gain measurement

PLXNA2 SDK2

3.12e-03123202EFO_0008433
Diseaseirritable bowel syndrome

COP1 LIG4

3.53e-03131202EFO_0000555

Protein segments in the cluster

PeptideGeneStartEntry
YFSTRMSRISDDSRT

COP1

371

Q8NHY2
YHVRSRSSYDDRSSD

CLK2

51

P49760
SRSSYDMYHLSREGE

KIR2DS2

151

P43631
SRSSYDMYHLSREGE

KIR2DL2

151

P43627
SRSSYDMYHLSREGE

KIR2DS4

151

P43632
SRSSYDMYHLSREGE

KIR2DL3

151

P43628
TTSRDRMTSVASYVY

PLXNA2

426

O75051
LHHTSYMYNIESRRS

PDE6C

226

P51160
YTVTMDVHSRYRTEA

NAT10

161

Q9H0A0
SRSSYDMYHLSREGE

KIR2DS5

151

Q14953
SMFRRHTVYLDSYAV

LIG4

811

P49917
SMHTYSQPYSARSRL

CLDN12

216

P56749
YVSDEHTYSRSSRRM

BEAN1

96

Q3B7T3
HTYSRSSRRMRYACS

BEAN1

101

Q3B7T3
SLEYRYMITSLDRTH

SDK2

71

Q58EX2
SYMEHYCNSSTDRRV

SPACA9

51

Q96E40
SRSSYDMYHLSREGE

KIR2DL1

151

P43626
SRSSYDMYHLSREGE

KIR2DS1

151

Q14954
RSSYRSAIDYSDSAM

CARS2

346

Q9HA77
YSMSEDVRQRHRYLS

RNF10

551

Q8N5U6
SYTFAYRTQLERHMT

ZEB1

206

P37275
FYSSYRRHERMHTGE

ZNF563

236

Q8TA94
CDYYAVTRREMTRHA

ZNF407

1051

Q9C0G0