Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II C-terminal domain binding	SCAF1 HNRNPU	2.82e-04	11	46	2	GO:0099122
GeneOntologyMolecularFunction	tubulin binding	KIF21B NEFH DST CCDC88B GOLGA2 NISCH	4.24e-04	428	46	6	GO:0015631
GeneOntologyMolecularFunction	microtubule binding	KIF21B NEFH DST CCDC88B GOLGA2	6.90e-04	308	46	5	GO:0008017
GeneOntologyMolecularFunction	integrin binding	THBS4 DST COMP NISCH	6.98e-04	175	46	4	GO:0005178
Domain	TSP_3	THBS2 THBS4 COMP	1.39e-07	5	46	3	PF02412
Domain	TSP3	THBS2 THBS4 COMP	1.39e-07	5	46	3	PS51234
Domain	TSP_CTER	THBS2 THBS4 COMP	1.39e-07	5	46	3	PS51236
Domain	-	THBS2 THBS4 COMP	1.39e-07	5	46	3	4.10.1080.10
Domain	Thrombospondin_C	THBS2 THBS4 COMP	1.39e-07	5	46	3	IPR008859
Domain	TSP_C	THBS2 THBS4 COMP	1.39e-07	5	46	3	PF05735
Domain	Thrombospondin_3_rpt	THBS2 THBS4 COMP	1.39e-07	5	46	3	IPR017897
Domain	Thrombospondin_3-like_rpt	THBS2 THBS4 COMP	1.39e-07	5	46	3	IPR003367
Domain	TSP_type-3_rpt	THBS2 THBS4 COMP	1.39e-07	5	46	3	IPR028974
Domain	ConA-like_dom	THBS2 THBS4 COMP TRIM41 RYR1 HNRNPU	1.54e-05	219	46	6	IPR013320
Domain	Thbs/COMP_coiled-coil	THBS4 COMP	1.78e-05	3	46	2	IPR024665
Domain	COMP	THBS4 COMP	1.78e-05	3	46	2	PF11598
Domain	GOLGA2L5	GOLGA6L2 GOLGA2	8.85e-04	18	46	2	PF15070
Domain	Golgin_A	GOLGA6L2 GOLGA2	8.85e-04	18	46	2	IPR024858
Domain	EGF_CA	THBS2 THBS4 COMP	1.24e-03	86	46	3	PF07645
Domain	SPRY	TRIM41 RYR1 HNRNPU	1.28e-03	87	46	3	SM00449
Domain	ARM-type_fold	RIPOR2 USP35 SAAL1 UPF2 ARMC5	1.42e-03	339	46	5	IPR016024
Domain	TSPN	THBS2 THBS4	1.45e-03	23	46	2	SM00210
Domain	SPRY	TRIM41 RYR1 HNRNPU	1.60e-03	94	46	3	PF00622
Domain	SPRY_dom	TRIM41 RYR1 HNRNPU	1.60e-03	94	46	3	IPR003877
Domain	B30.2/SPRY	TRIM41 RYR1 HNRNPU	1.65e-03	95	46	3	IPR001870
Domain	B302_SPRY	TRIM41 RYR1 HNRNPU	1.65e-03	95	46	3	PS50188
Domain	-	THBS2 THBS4 COMP	1.65e-03	95	46	3	2.60.120.200
Domain	EGF_CA	THBS2 THBS4 COMP	3.36e-03	122	46	3	SM00179
Domain	EGF-like_Ca-bd_dom	THBS2 THBS4 COMP	3.52e-03	124	46	3	IPR001881
Domain	ARM-like	RIPOR2 USP35 SAAL1 ARMC5	4.33e-03	270	46	4	IPR011989
Domain	PTB	ANKS1B FAM43A	4.36e-03	40	46	2	SM00462
Domain	PTB/PI_dom	ANKS1B FAM43A	4.58e-03	41	46	2	IPR006020
Domain	-	ZCCHC2 NISCH	7.01e-03	51	46	2	3.30.1520.10
Domain	Phox	ZCCHC2 NISCH	7.28e-03	52	46	2	IPR001683
Domain	Laminin_G	THBS2 THBS4	8.99e-03	58	46	2	IPR001791
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST LEMD3 NISCH	1.26e-04	42	33	3	M41826
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST LEMD3 NISCH	1.35e-04	43	33	3	M41827
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	THBS2 THBS4 COMP	2.31e-08	5	47	3	30622267
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	THBS2 THBS4 COMP	1.29e-07	8	47	3	24460873
Pubmed	Biophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2.	THBS2 THBS4	1.79e-06	2	47	2	16246837
Pubmed	Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.	COMP F2	1.79e-06	2	47	2	26045608
Pubmed	Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.	THBS2 THBS4	1.79e-06	2	47	2	27160021
Pubmed	Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.	THBS2 COMP	1.79e-06	2	47	2	23875975
Pubmed	COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.	THBS4 COMP	1.79e-06	2	47	2	30464261
Pubmed	Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.	THBS2 THBS4	1.79e-06	2	47	2	17182969
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANKS1B KIF21B NEFH NES DST HCN4 GOLGA2 NISCH HNRNPU	4.88e-06	963	47	9	28671696
Pubmed	Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.	THBS2 THBS4	5.36e-06	3	47	2	15121769
Pubmed	Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.	THBS4 COMP	5.36e-06	3	47	2	33910854
Pubmed	Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.	THBS2 THBS4	5.36e-06	3	47	2	12482844
Pubmed	Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.	THBS2 COMP	5.36e-06	3	47	2	26168731
Pubmed	Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.	THBS2 THBS4	5.36e-06	3	47	2	25976449
Pubmed	Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.	THBS2 THBS4	5.36e-06	3	47	2	18178577
Pubmed	Developmental expression of BPAG1-n: insights into the spastic ataxia and gross neurologic degeneration in dystonia musculorum mice.	NEFH DST	5.36e-06	3	47	2	9242412
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	KDM2A THBS4 COMP	1.01e-05	31	47	3	31550482
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS2 THBS4	1.07e-05	4	47	2	6338048
Pubmed	Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development.	NEFH NES	1.07e-05	4	47	2	8951795
Pubmed	Characterization of long cDNA clones from human adult spleen.	KDM2A OGFR ARMC5	1.23e-05	33	47	3	11214971
Pubmed	Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.	NES THBS2 THBS4	1.47e-05	35	47	3	35858542
Pubmed	Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein.	NEFH NES	1.78e-05	5	47	2	20353824
Pubmed	The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons.	NEFH DST	1.78e-05	5	47	2	9971739
Pubmed	Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.	THBS4 COMP	1.78e-05	5	47	2	18467703
Pubmed	Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.	NEFH RYR1	2.67e-05	6	47	2	31804576
Pubmed	Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions.	NEFH NES	4.98e-05	8	47	2	21832185
Pubmed	Expression of olig2 in retinal progenitor cells.	NEFH NES	4.98e-05	8	47	2	16514356
Pubmed	Association of common promoter polymorphisms of MCP1 with hepatitis B virus clearance.	THBS2 THBS4	4.98e-05	8	47	2	17202846
Pubmed	Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a.	SETD1A NES	6.40e-05	9	47	2	38971831
Pubmed	Expression dynamics of lymphoid enhancer-binding factor 1 in terminal Schwann cells, dermal papilla, and interfollicular epidermis.	NEFH NES	6.40e-05	9	47	2	36576725
Pubmed	Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system.	NEFH NES	6.40e-05	9	47	2	7720210
Pubmed	Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex.	NEFH NES	7.99e-05	10	47	2	11516395
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	NEFH DST UPF2 LEMD3 GOLGA2 HNRNPU	8.35e-05	538	47	6	28524877
Pubmed	Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.	NEFH RYR1	9.75e-05	11	47	2	31199454
Pubmed	Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA.	NEFH NES	9.75e-05	11	47	2	31577226
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	WRNIP1 ANKS1B NEFH NES THBS4 DST UPF2 NISCH HNRNPU	1.09e-04	1431	47	9	37142655
Pubmed	Transcriptomic analysis of mouse limb tendon cells during development.	THBS2 THBS4	1.17e-04	12	47	2	25249460
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	KIF21B NEFH DST HNRNPU	1.20e-04	187	47	4	26460568
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	NES KDM2A DST GOLGA2 HNRNPU	1.24e-04	360	47	5	33111431
Pubmed	Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1).	NEFH RYR1	1.38e-04	13	47	2	30870432
Pubmed	Fate-restricted neural progenitors in the mammalian cerebral cortex.	NEFH NES	1.38e-04	13	47	2	22879516
Pubmed	ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells.	NEFH IRX4	1.38e-04	13	47	2	18434421
Pubmed	MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex.	NEFH NES	1.61e-04	14	47	2	29082311
Pubmed	Perlecan maintains the integrity of cartilage and some basement membranes.	NES COMP	1.86e-04	15	47	2	10579729
Pubmed	Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor.	NEFH NES	1.86e-04	15	47	2	22241839
Pubmed	The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.	NES KDM2A	1.86e-04	15	47	2	25463925
Pubmed	Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.	NEFH IRX4	2.12e-04	16	47	2	15647317
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DST UPF2 GOLGA2 NISCH ARMC5 HNRNPU	2.33e-04	650	47	6	38777146
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	RIPOR2 ARMC5	2.40e-04	17	47	2	28169274
Pubmed	Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex.	NEFH NES	2.40e-04	17	47	2	18940588
Pubmed	Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.	NEFH NES	2.40e-04	17	47	2	21315259
Pubmed	N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.	NES GOLGA2	2.70e-04	18	47	2	24227724
Pubmed	A physical interaction network of dengue virus and human proteins.	DST GOLGA2	2.70e-04	18	47	2	21911577
Pubmed	Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons.	NEFH NES	2.70e-04	18	47	2	17913789
Pubmed	Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.	NEFH NES	2.70e-04	18	47	2	17589506
Pubmed	Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice.	NEFH NES	3.01e-04	19	47	2	21844226
Pubmed	ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.	NEFH NES	3.01e-04	19	47	2	20619750
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ZNF787 PRMT6 FGD5 LEMD3 ZC3H6 ZNF646	3.18e-04	689	47	6	36543142
Pubmed	Dual embryonic origin of the mammalian enteric nervous system.	NEFH NES	3.34e-04	20	47	2	30472119
Pubmed	Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments.	NEFH NES	3.34e-04	20	47	2	34091985
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SCAF1 DST CENPB OGFR NISCH ANO8	3.38e-04	697	47	6	28298427
Pubmed	Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.	THBS2 THBS4	3.69e-04	21	47	2	20227257
Pubmed	Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.	NEFH NES	3.69e-04	21	47	2	25382142
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A RIPOR2 ZNF646	3.83e-04	104	47	3	9205841
Pubmed	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	ANKS1B MAP3K9	4.06e-04	22	47	2	21107309
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	WRNIP1 ZCCHC2 GPR162 OGFR TRIM41 ANO8 HNRNPU	4.15e-04	1021	47	7	26760575
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MAP3K9 SCAF1 THBS4 DST RYR1 HNRNPU	4.52e-04	736	47	6	29676528
Pubmed	Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.	NES GOLGA2	4.84e-04	24	47	2	26060116
Pubmed	Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice.	NES GOLGA2	4.84e-04	24	47	2	18434600
Pubmed	Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation.	HCN4 ARID3B	4.84e-04	24	47	2	34062094
Pubmed	A human MAP kinase interactome.	KDM2A RIPOR2 DST CCDC88B GOLGA2	4.94e-04	486	47	5	20936779
Pubmed	Zbtb20 modulates the sequential generation of neuronal layers in developing cortex.	NEFH NES	5.26e-04	25	47	2	27282384
Pubmed	A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.	NES GOLGA2	5.26e-04	25	47	2	29587143
Pubmed	Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.	NES NISCH	5.26e-04	25	47	2	29311744
Pubmed	Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.	NEFH NES	5.26e-04	25	47	2	24595293
Pubmed	CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.	NES GOLGA2	5.69e-04	26	47	2	22806269
Pubmed	Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo.	NES GOLGA2	5.69e-04	26	47	2	31655624
Pubmed	Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.	NEFH NES	5.69e-04	26	47	2	17875933
Pubmed	The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.	KIF21B NES	6.61e-04	28	47	2	24448406
Pubmed	Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.	NEFH NES	7.09e-04	29	47	2	29874580
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	WRNIP1 SETD1A ARID3B	8.01e-04	134	47	3	25452129
Pubmed	Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.	NES GOLGA2	8.11e-04	31	47	2	17765678
Pubmed	Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice.	NEFH NES	8.64e-04	32	47	2	19571125
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	WRNIP1 ZCCHC2 CCDC88B GPR162 GOLGA2	9.34e-04	560	47	5	21653829
Pubmed	SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.	NES GOLGA2	1.03e-03	35	47	2	39366759
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	DST HNRNPU	1.03e-03	35	47	2	22337587
Pubmed	Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse.	COMP GOLGA2	1.28e-03	39	47	2	21606205
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	WRNIP1 ZNF787 KIF21B SCAF1 THBS2	1.31e-03	604	47	5	38803224
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	KIF21B NEFH	1.35e-03	40	47	2	29078390
Cytoband	16p11.2	SETD1A ARMC5 ZNF646	1.00e-03	191	47	3	16p11.2
GeneFamily	Intermediate filaments Type IV	NEFH NES	4.25e-05	6	31	2	611
Coexpression	NABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS	THBS2 COMP F2	2.12e-05	30	47	3	M47990
Coexpression	GSE11924_TFH_VS_TH2_CD4_TCELL_UP	UPF2 CCDC88B NISCH TRIM41 ZNF646	2.91e-05	200	47	5	M3153
ToppCell	P07-Endothelial-lymphatic_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS4 COMP SLC24A1 FAM43A	2.62e-05	163	47	4	5cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCell	P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS4 COMP SLC24A1 FAM43A	2.62e-05	163	47	4	322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS4 COMP FAM43A	3.46e-05	175	47	4	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS4 COMP FAM43A	3.46e-05	175	47	4	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NES KDM2A THBS2 COMP	3.70e-05	178	47	4	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	THBS4 DST DMRT2 FAM43A	4.12e-05	183	47	4	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	THBS4 DST DMRT2 FAM43A	4.21e-05	184	47	4	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	THBS4 DST DMRT2 FAM43A	4.48e-05	187	47	4	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	moderate-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	THBS4 DST DMRT2 FAM43A	4.67e-05	189	47	4	6011b747e27d61d222380a7bffdd921a68e9b657
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	THBS4 DST DMRT2 FAM43A	4.77e-05	190	47	4	05a2c3549b68f49081723bf35db14974274419d5
Disease	Nephrosis	NES F2	2.46e-04	15	46	2	C0027720
Disease	leprosy	PRMT6 ANKS1B CCDC88B	5.62e-04	103	46	3	EFO_0001054
Disease	congestive heart failure (is_implicated_in)	NISCH RYR1	8.14e-04	27	46	2	DOID:6000 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGLEDEDGDDEVAEV	ARID3B	96	Q8IVW6
GLVGEAEDSEGEEEE	CCDC88B	26	A6NC98
GRGDACDDDIDGDRI	COMP	366	P49747
CGEAGEEEEEGREAA	ARMC5	421	Q96C12
EEDEEEGEEGGLLDC	ANO8	596	Q9HCE9
YAEGEEEEGGEEEAR	IRX4	221	P78413
AVEDEEGEGEDGEER	LEMD3	216	Q9Y2U8
PGEVEEEDDDENTCG	ANKS1B	386	Q7Z6G8
GEECEDENEAEGKGD	SLC24A1	791	O60721
RLEDEEDEEEAEGGG	GPR162	461	Q16538
DDDDGIDEEGGGIRD	DST	2596	Q03001
AEEEEEREEGGEACG	FGD5	96	Q6ZNL6
EEERDESGCEEEEGR	KIF21B	591	O75037
ESGCEEEEGREDEDE	KIF21B	596	O75037
GEDELGDEEEGAGDE	HNRNPU	141	Q00839
EGEEGEEECGRDSDL	NES	1351	P48681
EESGEEGEEDQEEGR	NES	1416	P48681
EEDAGGEDAGAARED	GOLGA6L2	761	Q8N9W4
GEGDGLDREEEEDEE	GOLGA2	696	Q08379
MDEEEDAEEEGAGGR	HCN4	26	Q9Y3Q4
EEGGEEEEAEGGEEE	NEFH	486	P12036
NDGEVDGEEDEEELG	ANP32C	211	O43423
DGEEDEEELGEEERG	ANP32C	216	O43423
EEEEEGGEGEELGEE	CENPB	431	P07199
GGEGEELGEEEEVEE	CENPB	436	P07199
QRGDEEGLGGEEEEE	KDM2A	846	Q9Y2K7
PADGDCEDDEDDDGV	DMRT2	41	Q9Y5R5
QGDGEEEEEEERGRG	FERD3L	71	Q96RJ6
EGGEGTEEEDGAERE	PRMT6	16	Q96LA8
EGCPEEEENRAAEGD	FAM43A	276	Q8N2R8
GRDKEEEEEVAGGDC	SAAL1	11	Q96ER3
EEGGENGEAEEEVEV	RYR1	3736	P21817
GEDGAGAGAEEEEEE	MAP3K9	21	P80192
GENLEEDEEEEEGGA	UPF2	1026	Q9HAU5
EDEDCEDGEAAGARD	OGFR	21	Q9NZT2
GEEEGEEEEEAEGGR	RSPH4A	506	Q5TD94
EDGEEEEVEAVGAGA	TRIM41	66	Q8WV44
QQREEGEEEGEEEGE	SETD1A	1356	O15047
DFDEEEDGDEVCNVG	RIPOR2	671	Q9Y4F9
GAEDERGEDGDGEQD	ZCCHC2	216	Q9C0B9
EDADRDGIGDACDED	THBS4	496	P35443
REDGELEDGEIDDAG	ZC3H6	11	P61129
GVRGGAEEEEEEEEE	SCAF1	1016	Q9H7N4
EEVGEEEESTRGEGE	USP35	691	Q9P2H5
DVEEEEGGGQGEEEE	NISCH	661	Q9Y2I1
EGGGQGEEEEEEEED	NISCH	666	Q9Y2I1
EGSEEEGEEEGVAEA	ZNF646	911	O15015
EEEEEEEEEGGGSGR	ZBTB47	286	Q9UFB7
EEEEGGGSGREEEEE	ZBTB47	291	Q9UFB7
EAQEEEEAVGDGDGD	WRNIP1	161	Q96S55
GGVCTEGAAEEEEEA	TEX13A	166	Q9BXU3
CEEAVEEETGDGLDE	F2	291	P00734
EDLDGDGRGDICKDD	THBS2	921	P35442
RAGGEEEDDDDEAAG	ZNF787	356	Q6DD87
EEDDDDEAAGGRCPE	ZNF787	361	Q6DD87